CN111569248A - Treatment method and treatment system for patients with autism - Google Patents

Treatment method and treatment system for patients with autism Download PDF

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CN111569248A
CN111569248A CN202010446012.2A CN202010446012A CN111569248A CN 111569248 A CN111569248 A CN 111569248A CN 202010446012 A CN202010446012 A CN 202010446012A CN 111569248 A CN111569248 A CN 111569248A
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李玉榕
袁丁
***
杜民
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Fuzhou University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/398Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
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Abstract

A method and system for treating an autistic patient is provided. The treatment method comprises the following steps: acquiring an electro-oculogram signal to be compared of a patient to be treated within a preset time, an electro-oculogram template corresponding to the patient to be treated and an error threshold corresponding to the electro-oculogram template; acquiring a comparison difference value between an electro-oculogram signal to be compared and an electro-oculogram template; if the comparison difference is smaller than the error threshold, sending a starting command to the electrotherapy device installed on the affected part through wireless communication; the electrotherapy device is started according to the starting command. By implementing the embodiment of the invention, the electrotherapy equipment can start electrotherapy only when a patient is conscious, thereby improving the effect of electrotherapy.

Description

Treatment method and treatment system for patients with autism
Technical Field
The application belongs to the field of electrotherapy, and particularly relates to a treatment method and a treatment system for patients with autism.
Background
Autism Spectrum Disorder (ASD), also known as pervasive developmental disorder or autism, is defined as a developmental disorder characterized primarily by social interaction and communication disorders, a narrow range of interest, and repetitive stereotyped behaviors. Medical research shows that acupuncture on points with long strength can improve mental retardation of various children including autism. Moreover, according to clinical experience, the acupuncture treatment can be performed with half the effort if the children with autism can consciously perform the acupuncture treatment. The current acupuncture treatment scheme for autism in clinic is that a child gets to a hospital and receives acupuncture treatment of a doctor, and the following problems exist: electrotherapy is usually performed randomly, and doctors cannot continuously observe the mental state of the children with autism, so that the doctors cannot judge the conscious moment of the children patients in real time to perform the electro-acupuncture stimulation treatment.
Chinese patent application No. CN201820627380.5 discloses that whether the autism patient has consciousness or not is judged through the eye electrical signal, and then the device for electric shock treatment is carried out, and the device compares the eye electrical signal to be compared of all the patients with the same eye electrical template to judge whether the autism patient has consciousness or not, and does not separately set the eye electrical template for different patients, which may cause the consciousness judgment to have an error, affecting the treatment effect.
Disclosure of Invention
The invention mainly aims to provide a method and a system for treating patients with autism.
In a first aspect, there is provided a method of treatment of a patient with autism comprising:
acquiring an electro-oculogram signal to be compared of a patient to be treated within a preset time, an electro-oculogram template corresponding to the patient to be treated and an error threshold corresponding to the electro-oculogram template;
acquiring a comparison difference value between an electro-oculogram signal to be compared and an electro-oculogram template;
if the comparison difference is smaller than the error threshold, sending a starting command to the electrotherapy device installed on the affected part through wireless communication;
the electrotherapy device is started according to the start command.
In one possible implementation, the electro-ocular template and the error threshold corresponding to the electro-ocular template are established based on the patient's electro-ocular signals over a conscious time interval.
In another possible implementation, acquiring an electrooculogram template of a patient to be treated and an error threshold corresponding to the electrooculogram template includes:
setting a total sampling period of an electro-oculogram template of a patient to be treated, and dividing the total sampling period into a plurality of sampling sub-periods with the same time in half;
collecting the electro-ocular signals in a plurality of sampling sub-periods;
acquiring a sampling sub-period of which the existence time of the electro-oculogram signal is greater than a preset time threshold, and setting the sampling sub-period as an electro-oculogram pre-template;
acquiring a sampling sub-period with maximum intensity and minimum intensity of an electro-oculogram signal from the electro-oculogram pre-template;
and setting the eye electrical signal with the maximum intensity as an eye electrical template, and setting the difference value of the eye electrical signal with the maximum intensity and the eye electrical signal with the minimum intensity as an error threshold value.
In another possible implementation, the preset time is a play period of the visual stimulation system.
In another possible implementation, the comparison difference or the difference is calculated by a dynamic time warping algorithm DTW.
In a second aspect, there is provided a treatment system for an autistic patient, the treatment system comprising:
the system comprises an acquisition module, a comparison module and a comparison module, wherein the acquisition module is used for acquiring an electro-oculogram signal to be compared of a patient to be treated within preset time, an electro-oculogram template corresponding to the patient to be treated and an error threshold corresponding to the electro-oculogram template;
a comparison difference value acquisition module for acquiring the comparison difference value between the electro-oculogram signal to be compared and the electro-oculogram template
A start command transmitting module for transmitting a start command to the electrotherapy apparatus installed at the affected part through wireless communication if the comparison difference is smaller than the error threshold;
and the starting module is used for starting the electrotherapy equipment according to the starting command.
In one possible implementation, the electro-ocular template and the error threshold corresponding to the electro-ocular template are established based on the patient's electro-ocular signals over a conscious time interval.
In another possible implementation, acquiring an electrooculogram template of a patient to be treated and an error threshold corresponding to the electrooculogram template includes:
setting a total sampling period of an electro-oculogram template of a patient to be treated, and dividing the total sampling period into a plurality of sampling sub-periods with the same time in half;
collecting the electro-ocular signals in a plurality of sampling sub-periods;
acquiring a sampling sub-period of which the existence time of the electro-oculogram signal is greater than a preset time threshold, and setting the sampling sub-period as an electro-oculogram pre-template;
acquiring a sampling sub-period with maximum intensity and minimum intensity of an electro-oculogram signal from the electro-oculogram pre-template;
and setting the eye electrical signal with the maximum intensity as an eye electrical template, and setting the difference value of the eye electrical signal with the maximum intensity and the eye electrical signal with the minimum intensity as an error threshold value.
In another possible implementation, the preset time is a play period of the visual stimulation system.
In another possible implementation, the comparison difference or the difference is calculated by a dynamic time warping algorithm DTW.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings used in the description of the embodiments of the present application will be briefly described below.
FIG. 1 is a flow chart of a method of treating an autism patient according to one embodiment of the present invention;
fig. 2 is a block diagram of a system for treating an autism patient in accordance with an embodiment of the present invention.
Detailed Description
Reference will now be made in detail to embodiments of the present application, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar modules or modules having the same or similar functionality throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present application and are not to be construed as limiting the present invention.
As used herein, the singular forms "a", "an", "the" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, modules, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, modules, components, and/or groups thereof. It will be understood that when a module is referred to as being "connected" or "coupled" to another module, it can be directly connected or coupled to the other module or intervening modules may also be present. Further, "connected" or "coupled" as used herein may include wirelessly connected or wirelessly coupled. As used herein, the term "and/or" includes all or any element and all combinations of one or more of the associated listed items.
To make the objects, technical solutions and advantages of the present application more clear, embodiments of the present application will be described in further detail below with reference to the accompanying drawings.
The technical solutions of the present application and the technical solutions of the present application, for example, to solve the above technical problems, will be described in detail with specific examples. The following several specific embodiments may be combined with each other, and details of the same or similar concepts or processes may not be repeated in some embodiments. Embodiments of the present application will be described below with reference to the accompanying drawings.
Example one
Fig. 1 is a flowchart of a method for treating an autism patient according to an embodiment of the present invention, which includes:
step S101, acquiring an electro-oculogram signal to be compared of a patient to be treated within a preset time, an electro-oculogram template corresponding to the patient to be treated and an error threshold corresponding to the electro-oculogram template.
In the embodiment of the invention, the corresponding electro-ocular template and the error threshold corresponding to the electro-ocular template are respectively set for each patient, and whether the patient consciously judges can be more accurate by comparing the corresponding electro-ocular template with the corresponding electro-ocular template.
The acquiring an electro-oculogram template of a patient to be treated and an error threshold corresponding to the electro-oculogram template includes:
setting a sampling total period of the electro-oculogram template of the patient to be treated, and dividing the sampling total period into a plurality of sampling sub-periods with the same time in half;
acquiring the electro-ocular signals in the plurality of sampling sub-periods;
acquiring a sampling sub-period of which the existence time of the electro-oculogram signal is greater than a preset time threshold, and setting the sampling sub-period as an electro-oculogram pre-template;
acquiring a sampling sub-period with maximum intensity and minimum intensity of an electro-oculogram signal from the electro-oculogram pre-template;
and setting the eye electrical signal with the maximum intensity as an eye electrical template, and setting the difference value of the eye electrical signal with the maximum intensity and the eye electrical signal with the minimum intensity as an error threshold value.
In the embodiment of the invention, a sampling total period (for example, 60 seconds) is set, the sampling total period is divided into a plurality of sampling sub-periods with the same time (for example, 10 sampling sub-periods are divided into, the duration of each sampling sub-period is 6 seconds), the electro-ocular signals of the plurality of sampling sub-periods are acquired through an electro-ocular signal acquisition device, the sampling sub-period of which the existence time of the electro-ocular signals is greater than a preset time threshold is acquired and set as an electro-ocular signal pre-template (for example, the time threshold is set to be 3 seconds, namely, the time of acquiring the electro-ocular signals in one sampling sub-period is greater than or equal to 3 seconds), the sampling sub-period with the maximum strength and the minimum strength of the electro-ocular signals is acquired from the electro-ocular signal pre-template, the electro-ocular signals with the maximum strength are set as the electro-ocular template, and the difference value between the electro.
Step S102, obtaining a comparison difference value between the electro-oculogram signal to be compared and the electro-oculogram template.
In an embodiment of the invention, a signal acquisition device mounted on the head of a patient to be treated acquires an ocular electrical signal to be compared of the patient in real time. The collection equipment usually attaches the metal electrode slice to the edge of the outer side of human eyes to realize the collection of the eye electrical signals. And comparing the collected electro-oculogram signals to be compared with a preset electro-oculogram template, and calculating a comparison difference value between the collected electro-oculogram signals to be compared and the electro-oculogram template.
And step S103, if the comparison difference value is smaller than a preset error threshold value, transmitting a starting command to the electrotherapy device installed at the affected part through wireless communication.
In the embodiment of the invention, the comparison difference between the electro-oculogram signal to be compared and the electro-oculogram template is obtained, if the comparison difference is smaller than the error threshold, the patient is conscious at the moment, the starting command is sent to the medical equipment installed at the affected part through wireless communication, and if the comparison difference is larger than the error threshold, the patient is unconscious at the moment, and the starting command is not sent.
Wherein the comparison difference and the difference are calculated by a dynamic time warping algorithm DTW.
DTW (Dynamic Time Warping) is the most common similarity measurement method in Time series classification, and can overcome phase distortion and match two given Time series with similar waveforms but unmatched Time lengths. DTW uses dynamic programming techniques to find the minimum distance between two time series where the series is distorted in size by stretching or shrinking the time. When the patient consciously watches the visual stimulation system under the guidance of the language to generate eye movement, the waveforms of the eye electrical signals have similarity, and when the patient is inactive, the eye movement is basically avoided. Therefore, the DTW is suitable for measuring the similarity between the collected electro-ocular signal and the electro-ocular signal template, and judging whether the electro-ocular signal is the target signal in conscious according to the magnitude relation between the DTW distance and the threshold value.
Step S104, starting the electrotherapy equipment according to the starting command.
In the embodiment of the invention, in order to reduce the discomfort caused by the electric wire for the patient, the data transmission is realized between the electrotherapy device and the signal acquisition device through wireless communication. For the wireless mode, the present application is not limited, and preferably, the wireless communication includes but is not limited to: bluetooth and WiFi.
Wherein the electro-ocular template is established based on the patient's electro-ocular signals over a conscious time interval. And the error threshold is obtained by calculating the difference value between the collected electrooculogram signals in the conscious interval and the electrooculogram template. The preset time is the playing period of the visual stimulation system.
According to the embodiment of the invention, the electro-oculogram signal of the patient to be treated is acquired, the difference value between the electro-oculogram signal acquired in unit time and the preset electro-oculogram template is calculated, if the difference value is smaller than the preset error threshold value, the starting command is sent to the electrotherapy equipment installed at the affected part through wireless communication, the electrotherapy equipment is started according to the starting command, so that the electrotherapy equipment starts electrotherapy when the patient is conscious, and the electrotherapy effect is improved.
As an optional embodiment of the present invention, after the acquiring an ocular electrical signal to be compared of a patient to be treated, an ocular electrical template corresponding to the patient to be treated, and an error threshold corresponding to the ocular electrical template, the treatment method further includes:
preprocessing the electro-ocular signals to be compared, wherein the preprocessing comprises the following steps: filtering processing, amplifying processing and A/D conversion.
In the embodiment of the present invention, the eye electrical signals acquired by the signal acquisition device are usually weak and include more interference signals, so that the acquired signals need to be filtered and amplified. The processed electrooculogram signals are converted into digital signals through A/D, and then the steps can be carried out.
Example two
Fig. 2 is a block diagram of a system for treating an autism patient according to an embodiment of the present invention, which includes:
the acquiring module 201 is configured to acquire an electro-oculogram signal to be compared of a patient to be treated within a preset time, an electro-oculogram template corresponding to the patient to be treated, and an error threshold corresponding to the electro-oculogram template.
In the embodiment of the invention, the treatment system respectively sets the corresponding electro-ocular template and the error threshold corresponding to the electro-ocular template for each patient, and whether the patient consciously judges can be more accurate through comparison with the corresponding electro-ocular template.
The acquiring an electro-oculogram template of a patient to be treated and an error threshold corresponding to the electro-oculogram template includes:
setting a sampling total period of the electro-oculogram template of the patient to be treated, and dividing the sampling total period into a plurality of sampling sub-periods with the same time in half;
acquiring the electro-ocular signals in the plurality of sampling sub-periods;
acquiring a sampling sub-period of which the existence time of the electro-oculogram signal is greater than a preset time threshold, and setting the sampling sub-period as an electro-oculogram pre-template;
acquiring a sampling sub-period with maximum intensity and minimum intensity of an electro-oculogram signal from the electro-oculogram pre-template;
and setting the eye electrical signal with the maximum intensity as an eye electrical template, and setting the difference value of the eye electrical signal with the maximum intensity and the eye electrical signal with the minimum intensity as an error threshold value.
In the embodiment of the invention, a sampling total period (for example, 60 seconds) is set, the sampling total period is divided into a plurality of sampling sub-periods with the same time (for example, 10 sampling sub-periods are divided into, the duration of each sampling sub-period is 6 seconds), the electro-ocular signals of the plurality of sampling sub-periods are acquired through an electro-ocular signal acquisition device, the sampling sub-period of which the existence time of the electro-ocular signals is greater than a preset time threshold is acquired and set as an electro-ocular signal pre-template (for example, the time threshold is set to be 3 seconds, namely, the time of acquiring the electro-ocular signals in one sampling sub-period is greater than or equal to 3 seconds), the sampling sub-period with the maximum strength and the minimum strength of the electro-ocular signals is acquired from the electro-ocular signal pre-template, the electro-ocular signals with the maximum strength are set as the electro-ocular template, and the difference value between the electro.
A comparison difference obtaining module 202, configured to obtain a comparison difference between the to-be-compared electro-oculogram signal and the electro-oculogram template.
In an embodiment of the invention, the treatment system acquires the ocular electrical signals to be compared of the patient in real time through a signal acquisition device mounted on the head of the patient to be treated. The collecting device usually attaches the metal electrode plate to the edge of the outer side of human eyes to collect the eye electrical signals, compares the collected eye electrical signals to be compared with a preset eye electrical template, and calculates the comparison difference value between the collected eye electrical signals to be compared and the eye electrical template. .
And a starting command sending module 203 for sending a starting command to the electrotherapy device installed at the affected part through wireless communication if the comparison difference is smaller than the error threshold.
In the embodiment of the invention, the treatment system acquires the comparison difference between the electro-oculogram signal to be compared and the electro-oculogram template, if the comparison difference is smaller than the error threshold, the patient is conscious at the moment, the starting command is sent to the medical equipment installed at the affected part through wireless communication, and if the comparison difference is larger than the error threshold, the patient is not conscious at the moment, the starting command is not sent.
Wherein the comparison difference and the difference are calculated by a dynamic time warping algorithm DTW.
DTW (Dynamic Time Warping) is the most common similarity measurement method in Time series classification, and can overcome phase distortion and match two given Time series with similar waveforms but unmatched Time lengths. DTW uses dynamic programming techniques to find the minimum distance between two time series where the series is distorted in size by stretching or shrinking the time. When the patient consciously watches the visual stimulation system under the guidance of the language to generate eye movement, the waveforms of the eye electrical signals have similarity, and when the patient is inactive, the eye movement is basically avoided. Therefore, the DTW is suitable for measuring the similarity between the collected electro-ocular signal and the electro-ocular signal template, and judging whether the electro-ocular signal is the target signal in conscious according to the magnitude relation between the DTW distance and the threshold value.
A starting module 204, configured to start the electrotherapy device according to the start command.
In the embodiment of the invention, in order to reduce the discomfort caused by the electric wire for the patient, the data transmission is realized between the electrotherapy device and the signal acquisition device through wireless communication. For the wireless mode, the present application is not limited, and preferably, the wireless communication includes but is not limited to: bluetooth and WiFi.
Wherein the electro-ocular template is established based on the patient's electro-ocular signals over a conscious time interval. And the error threshold is obtained by calculating the difference value between the collected electrooculogram signals in the conscious interval and the electrooculogram template. The preset time is the playing period of the visual stimulation system.
According to the embodiment of the invention, the electro-oculogram signal of the patient to be treated is acquired, the difference value between the electro-oculogram signal acquired in unit time and the preset electro-oculogram template is calculated, if the difference value is smaller than the preset error threshold value, the starting command is sent to the electrotherapy equipment installed at the affected part through wireless communication, the electrotherapy equipment is started according to the starting command, so that the electrotherapy equipment starts electrotherapy when the patient is conscious, and the electrotherapy effect is improved.
As an alternative embodiment of the invention, the treatment system further comprises:
the preprocessing module is used for preprocessing the electro-ocular signal to be compared, and the preprocessing comprises the following steps: filtering processing, amplifying processing and A/D conversion.
In the embodiment of the present invention, the eye electrical signals acquired by the signal acquisition device are usually weak and include more interference signals, so that the acquired signals need to be filtered and amplified. The processed electrooculogram signals are converted into digital signals through A/D, and then the steps can be carried out.
It should be understood that, although the steps in the flowcharts of the figures are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and may be performed in other orders unless explicitly stated herein. Moreover, at least a portion of the steps in the flow chart of the figure may include multiple sub-steps or multiple stages, which are not necessarily performed at the same time, but may be performed at different times, which are not necessarily performed in sequence, but may be performed alternately or alternately with other steps or at least a portion of the sub-steps or stages of other steps.
The foregoing is only a partial embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (10)

1. A method of treating an autistic patient, comprising:
acquiring an electro-oculogram signal to be compared of a patient to be treated within a preset time, an electro-oculogram template corresponding to the patient to be treated and an error threshold corresponding to the electro-oculogram template;
acquiring a comparison difference value between the electro-oculogram signal to be compared and the electro-oculogram template;
if the comparison difference is smaller than the error threshold, sending a starting command to an electrotherapy device installed at the affected part through wireless communication;
and starting the electrotherapy equipment according to the starting command.
2. The method of treatment of claim 1, wherein the electro-ocular template and the error threshold corresponding to the electro-ocular template are established based on an electro-ocular signal of the patient over a conscious time interval.
3. The method of claim 2, wherein the obtaining an electro-ocular template of the patient to be treated and an error threshold corresponding to the electro-ocular template comprises:
setting a sampling total period of the electro-oculogram template of the patient to be treated, and dividing the sampling total period into a plurality of sampling sub-periods with the same time in half;
acquiring the electro-ocular signals in the plurality of sampling sub-periods;
acquiring a sampling sub-period of which the existence time of the electro-oculogram signal is greater than a preset time threshold, and setting the sampling sub-period as an electro-oculogram pre-template;
acquiring a sampling sub-period with maximum intensity and minimum intensity of an electro-oculogram signal from the electro-oculogram pre-template;
and setting the eye electrical signal with the maximum intensity as an eye electrical template, and setting the difference value of the eye electrical signal with the maximum intensity and the eye electrical signal with the minimum intensity as an error threshold value.
4. The treatment method of claim 1, wherein the predetermined time is a play period of the visual stimulation system.
5. The treatment of any one of claims 1 to 4, wherein the comparison difference or differences are calculated by a dynamic time warping algorithm DTW.
6. A treatment system for an autistic patient, the treatment system comprising:
the system comprises an acquisition module, a comparison module and an error threshold value acquisition module, wherein the acquisition module is used for acquiring an electro-oculogram signal to be compared of a patient to be treated within preset time, an electro-oculogram template corresponding to the patient to be treated and the error threshold value corresponding to the electro-oculogram template;
the comparison difference value acquisition module is used for acquiring a comparison difference value between the electro-oculogram signal to be compared and the electro-oculogram template;
a starting command sending module for sending a starting command to the electrotherapy device installed on the affected part through wireless communication if the comparison difference is smaller than the error threshold;
and the starting module is used for starting the electrotherapy equipment according to the starting command.
7. The treatment system of claim 6, wherein the electro-ocular template and the error threshold corresponding to the electro-ocular template are established based on an electro-ocular signal of the patient over a conscious time interval.
8. The treatment system of claim 7, wherein the obtaining of the electro-ocular template of the patient to be treated and the error threshold corresponding to the electro-ocular template comprises:
setting a sampling total period of the electro-oculogram template of the patient to be treated, and dividing the sampling total period into a plurality of sampling sub-periods with the same time in half;
acquiring the electro-ocular signals in the plurality of sampling sub-periods;
acquiring a sampling sub-period of which the existence time of the electro-oculogram signal is greater than a preset time threshold, and setting the sampling sub-period as an electro-oculogram pre-template;
acquiring a sampling sub-period with maximum intensity and minimum intensity of an electro-oculogram signal from the electro-oculogram pre-template;
and setting the eye electrical signal with the maximum intensity as an eye electrical template, and setting the difference value of the eye electrical signal with the maximum intensity and the eye electrical signal with the minimum intensity as an error threshold value.
9. The treatment system of claim 6, wherein the predetermined time is a play period of the visual stimulation system.
10. A therapeutic system according to any one of claims 6 to 9 wherein the comparison difference or differences are calculated by a dynamic time warping algorithm DTW.
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