CN111544668A - Multi-parameter thyroid postoperative drainage information active monitoring system based on Internet of things technology - Google Patents
Multi-parameter thyroid postoperative drainage information active monitoring system based on Internet of things technology Download PDFInfo
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Abstract
The invention relates to the technical field of medical monitoring systems, in particular to an active monitoring system for drainage information after multi-parameter thyroid surgery based on the technology of Internet of things, which comprises: the system comprises a drainage tube, a wireless pressure detection system, a drainage liquid color intelligent identification system, a multi-parameter fusion acquisition system and an integration system, wherein the integration system is used for integrating the acquired pressure values, colors and flow signals and sending the signals to a mobile phone client and a computer cloud; and an alarm system. From the clinical application of the intelligent drainage monitoring system after thyroid operation, the invention explores a whole set of intelligent monitoring and early warning system through a heparin coating technology, a wireless pressure sensing technology, a flow meter system, a color identification sensing technology and an Internet of things technology, so as to prevent various dangerous complications, accelerate the early removal of a drainage tube during the recovery of a patient, increase the safety of medical treatment and assist the rapid recovery and the implementation of day surgery.
Description
Technical Field
The invention relates to the technical field of medical monitoring systems, in particular to an active monitoring system for drainage information after a multi-parameter thyroid operation based on the technology of the Internet of things.
Background
In recent years, the incidence of thyroid diseases is increasing year by year, the number of patients who receive thyroid surgery is increasing, and hospitals in provinces and cities successively establish departments or centers of head and neck specialties and even thyroid sub-specialties. With the development of surgical techniques, the popularization and application of new instruments and the increasingly mature specialized process, the thyroid surgery basically achieves the minimally invasive, functional and bloodless state, but the technical level is different between each region and medical units. The two most common critical complications after thyroid surgery are bleeding and dyspnea. With the popularization of nerve monitors and the improvement of surgical skills, the probability of recurrent laryngeal nerve injury is greatly reduced. While the other complication, bleeding problem is still more common, especially under the influence of uncertain factors such as anatomical variation, blood coagulation dysfunction and the like, even the most experienced surgeons cannot completely avoid the bleeding after the thyroid operation, if the bleeding is not treated timely due to the sealing of the neck cavity and the particularity of the thyroid anatomical structure, a small amount of bleeding (100 ml) in a short period can generate tracheal compression symptoms, 300-500 ml can cause the serious consequences of dyspnea, laryngeal edema and asphyxia death, the traditional drainage tube only plays a role in drainage and aims to lead the bleeding and the seepage in the operation area out of the neck, once the drainage fluid properties change, the change is usually found by family members or caregivers who accompany the drainage fluid without medical general knowledge in the first time, and the opportunity of reoperation is judged by palpation and visual perception of doctors and nurses, so that quantitative evaluation standards and accurate early warning cannot be achieved. Particularly, at night, the medical staff often cannot be found at the first time, and the number of the medical staff is insufficient at night, so that more serious results are easily caused. Moreover, until now, no reliable method can completely avoid postoperative bleeding of the thyroid gland, and the postoperative bleeding is still rare particularly under the conditions of total thyroidectomy, combined cervical lymph node cleaning, secondary operation and the like. Therefore, the development of the intelligent monitoring system after thyroid operation has urgent and very important practical significance.
The shortcomings of current post-operative medical monitoring modalities:
1. the bleeding early warning mechanism can not be established, the visual observation of medical or non-medical personnel is taken as the main point, and the intervention is started after the clinical symptoms are generated.
2. The tube drawing time can not be individualized, the tube drawing finger syndrome can not be unified and homogenized, the tube drawing finger syndrome commonly used in clinic at present is that the drainage tube is less than 10ml-20ml in 24 hours, and the drainage tube can be drawn out in 2-5 days after a doctor operates regardless of the amount of a drainage sample. Most patients discharged from hospital need 3-7 days after operation to meet the requirement, and whether tube drawing is safe and feasible when the drainage volume is larger is not supported by systematic data at present.
3. Negative pressure drainage is generally used in surgical operations, the principle is that body fluid exuded from a wound is collected into a drainage container under the action of a negative pressure source, only the pressure of the negative pressure source is controlled in the process, the flow velocity and the flow of the drainage fluid cannot be measured and controlled, faults affecting the drainage effect due to pipeline blockage and the like caused by various reasons in the using process cannot be found and processed in time, normal recovery of patients after the operation is affected, and even serious consequences such as complications are caused.
In summary, after an operation, no matter during hospitalization or after discharge, we can not actively monitor the neck condition and drainage condition of a patient, but manually count and monitor at a certain time node, and once serious complications occur, early warning and timely treatment cannot be performed frequently, and the consequences are not imaginable. How to utilize the existing wireless communication technology, the internet of things technology and the medicine coating technology to carry out multi-parameter fusion early warning is a problem that people always think for better monitoring the postoperative recovery condition of patients for medical care.
At present, some medical monitoring systems exist, for example, a special drainage liquid rapid monitoring system for postoperative galactophore surgery disclosed in 2018, 10 months and 2 days of chinese patent application with an authorization publication number CN106215252B, but is not suitable for postoperative thyroid gland monitoring.
Disclosure of Invention
The invention aims to provide a multi-parameter thyroid postoperative drainage information active monitoring system based on the internet of things technology, which provides early warning for high-risk complications of thyroid postoperative patients, enables medical staff to monitor neck conditions and vital signs of the patients in a 24-hour long distance, increases medical safety, can assist rapid rehabilitation and daily operation, and further provides reference experience and research basis for further development of other intelligent drainage tubes.
In order to achieve the above object, the present invention adopts the following technical scheme, a multi-parameter active monitoring system for postoperative drainage information of thyroid based on internet of things technology, comprising:
a drainage tube for draining fluid from the thyroid gland;
set up in drainage tube head end and arrange in thyroid bed and be used for monitoring the wireless pressure detection system of thyroid bed pressure:
the drainage liquid color intelligent identification system is used for collecting the color of the fluid in the drainage tube and analyzing the properties of the drainage liquid;
the multi-parameter fusion acquisition system is used for analyzing and counting the daily drainage quantity, the accumulated drainage quantity and the flow rate of the drainage tube;
the integration system is used for integrating the acquired pressure value, color and flow signal and sending the pressure value, color and flow signal to the mobile phone client and the computer cloud;
and an alarm system;
the drainage liquid color intelligent identification system and the multi-parameter fusion acquisition system are arranged at the relative positions of the drainage tube;
the alarm system, the wireless pressure detection system, the drainage liquid color intelligent identification system and the multi-parameter fusion acquisition system are connected with the integration system.
Preferably, the wireless pressure detection system is composed of the following four parts: the implanted wireless blood pressure sensor, the energy transmitting coil, the data reader and the data processing platform have the following working principles: the wireless blood pressure sensor is arranged on the neck thyroid bed through being fixed at the head end of the drainage tube; the data reader drives the energy transmitting coil to work, the energy transmitting coil starts to wirelessly transmit energy, and the wireless blood pressure sensor immediately starts to work; the wireless blood pressure sensor wirelessly transmits the detected intracavity pressure to the outside of the body, and the data reader receives and sends the intracavity pressure to the computer.
The implanted wireless blood pressure sensor is arranged on the neck thyroid bed through being fixed at the head end of the drainage tube; the data reader drives the energy transmitting coil to work, the energy transmitting coil starts to wirelessly transmit energy, and the wireless blood pressure sensor immediately starts to work; the wireless blood pressure sensor wirelessly transmits the detected intracavity pressure to the outside of the body, and the data reader receives and sends the intracavity pressure to the computer.
Preferably, the data reader consists of a receiving antenna, a radio frequency communication module, a special micro-processing chip and a data interface. The data is received from the wireless sensor in the body in real time in a wireless communication mode, and the data is transmitted to the data processing station through the data interface. And the pressure data in the cavity is stored, analyzed and displayed through a data processing platform and processing software.
Preferably, the alarm system comprises a bedside alarm system, a ward medical alarm system and a mobile phone intelligent alarm system for medical supervision.
Preferably, a heparin coating is arranged on the surface of the drainage tube. Heparin is fixedly attached to the surface of the biological material by adopting a specific method, so that the biocompatibility and the anticoagulation activity of the surface of the biological material are improved, and the postoperative systemic inflammatory reaction is reduced. The technology is applied to the inner membrane of the drainage tube, so that the formation probability of blood clots is reduced, and the drainage of the drainage tube is kept smooth to the greatest extent, so that the neck airway compression and local hematocele hydrops caused by the blockage of the drainage tube are reduced.
More optionally, a vertical groove is arranged on the wall of the drainage tube and positioned at the lower part of the drainage tube to replace the existing drainage tube side hole as a drainage inlet, so that the drainage tube is not easy to block.
Preferably, the surface of the drainage tube is provided with a heparin coating, and the heparin coating is formed according to the following method: adding 1, 1, 2-trifluorotrichloroethane and absolute ethyl alcohol into a polyethyleneimine water solution to prepare a polyethyleneimine ethanol solution, soaking a drainage tube into the polyethyleneimine ethanol solution, pouring out the residual solution after 30 minutes of water bath, and drying at a vacuum normal temperature; pouring the heparin aqueous solution into the pipeline, so that a thin layer of white precipitate is separated out on the surface of the pipeline, pouring out the residual solution after 30min of water bath at 37 ℃, and drying at the normal temperature in vacuum for later use.
By implementing the technical scheme, the invention explores a whole set of intelligent monitoring and early warning system from the clinical application of the intelligent drainage monitoring system after thyroid surgery through a heparin coating technology, a wireless pressure sensing technology, a flow meter system, a color identification sensing technology and an internet of things technology, so as to prevent various dangerous complications and accelerate the early removal of a drainage tube during the rehabilitation of a patient, increase the safety of medical treatment and assist the rapid rehabilitation and the implementation of day surgery.
Drawings
FIG. 1 shows the components of an intelligent thyroid monitoring system;
FIG. 2 is an internal exploded view of the wireless blood pressure sensor;
FIG. 3a is a schematic diagram of a flow meter and a circuit diagram;
FIG. 3b is a diagram of a flowmeter circuit configuration;
FIG. 4 is a diagram of signal filtering and A/D conversion of FIG. 3 b;
FIG. 5 is the excitation drive circuit of FIG. 3 b;
fig. 6 is partial interface of thyroid gland intelligent monitoring system cell-phone APP.
Detailed Description
The technical solution of the present invention is further described in detail by the following specific examples.
It should be noted that the present embodiment is only for explaining the present invention, and is not limited to the present invention. Any changes that may be made by one skilled in the art after reading the description of the invention herein will be covered by the patent laws within the scope of the appended claims.
A multi-parameter thyroid postoperative drainage information active monitoring system based on Internet of things technology, as shown in figure 1, includes:
a drainage tube for draining fluid from the thyroid gland;
set up in drainage tube head end and arrange in thyroid bed and be used for monitoring the wireless pressure detection system of thyroid bed pressure:
the drainage liquid color intelligent identification system is used for collecting the color of the fluid in the drainage tube and analyzing the properties of the drainage liquid;
the multi-parameter fusion acquisition system is used for analyzing and counting the daily drainage quantity, the accumulated drainage quantity and the flow rate of the drainage tube;
the integration system is used for integrating the acquired pressure value, color and flow signal and sending the pressure value, color and flow signal to the mobile phone client and the computer cloud;
and an alarm system;
the drainage liquid color intelligent recognition system and the multi-parameter fusion acquisition system are arranged at the relative positions of the drainage tube, and the positions are based on the detection of drainage liquid information in the drainage tube;
the alarm system, the wireless pressure detection system, the drainage liquid color intelligent identification system and the multi-parameter fusion acquisition system are connected with the integration system.
The development of medical technology has driven the research and application of biomedical materials, such as extracorporeal circulation technology, dialysis technology and hemofiltration technology, and the development and application of relevant biomedical materials are urgently needed. Biocompatibility is a major problem in the application of biomedical materials, and biological materials in contact with blood can trigger host defense mechanisms, particularly blood stabilization mechanisms, so that the cascade causes the occurrence of thrombus and embolism, thereby endangering the life of patients. There are two approaches to improving the biocompatibility of biomedical materials: firstly, an inert surface material is developed to avoid the excitation of host defense reaction; the second is to develop active biological surface materials to naturally control host defense reactions. The heparin coating technology is based on the second idea, and heparin is fixedly attached to the surface of the biological material by adopting a specific method, so that the biocompatibility and the anticoagulation activity of the surface of the biological material are improved, and the postoperative systemic inflammatory reaction is reduced. The technology is applied to the inner membrane of the drainage tube, so that the formation probability of blood clots is reduced, and the drainage of the drainage tube is kept smooth to the greatest extent, so that the neck airway compression and local hematocele hydrops caused by the blockage of the drainage tube are reduced.
The structure of the drainage tube is locally improved, and a vertical groove is arranged on the wall of the drainage tube and positioned at the lower part of the drainage tube to replace the existing drainage tube side hole as a drainage inlet, so that the drainage tube is not easy to block.
By H2SO4·K2MnO4The solution is used for acidifying the pipeline to form carboxyl (-COOH) on the surface of the material and amino (-NH) of the strong positive polyethyleneimine2) A large number of 'space arms' mainly comprising amino groups are constructed on the surface of the material, binding sites are increased, and then the space arms are combined with aldehyde groups (-CHO) at the tail end of the heparin after diazotization to prepare the covalent bond binding coating material. The method comprises the specific steps of taking 12.5ml of polyethyleneimine water solution with the mass fraction of 40%, adding 2.5ml of 1, 1, 2-trifluorotrichloroethane and 85ml of absolute ethyl alcohol, and preparing the 5% polyethyleneimine ethanol solution. Soaking the groove-type drainage tube (produced by Shichu corporation) in polyethyleneimine ethanol solution, water-bathing at 37 deg.C for 30min, pouring out the rest solution, repeating for 3 times, and vacuum drying at room temperature. And pouring a heparin aqueous solution (pH =1) with the mass fraction of 1% into the pipeline, so that a thin layer of white precipitate is separated out on the surface of the pipeline, pouring out the residual solution after 30min of water bath at 37 ℃, and drying at the normal temperature in vacuum for later use.
The wireless pressure detection system is a mature intracranial pressure monitoring and abdominal aortic aneurysm intracavity pressure measuring system at present. The latter is adopted in the present embodiment. Since the latter blood environment and thyroid bed environment are more similar and we can use drainage tubes as carriers to be placed in the thyroid bed. The pressure detection system comprises the following four parts: the implanted wireless blood pressure sensor, the energy transmitting coil, the data reader and the data processing platform have the following working principles: the wireless blood pressure sensor is arranged on the neck thyroid bed through being fixed at the head end of the drainage tube; the data reader drives the energy transmitting coil to work, the energy transmitting coil starts to wirelessly transmit energy, and the wireless blood pressure sensor immediately starts to work; the wireless blood pressure sensor wirelessly transmits the detected intracavity pressure to the outside of the body, and the data reader receives and sends the intracavity pressure to the computer. The data reader consists of a receiving antenna, a radio frequency communication module, a special micro-processing chip and a data interface. The data is received from the wireless sensor in the body in real time in a wireless communication mode, and the data is transmitted to the data processing station through the data interface. The intracavity pressure data is stored, analyzed and displayed through a data processing platform and processing software, as shown in figure 2.
The thyroid drainage liquid is led out of the body through the drainage tube, and the color of the liquid can be identified in the cavity of the body. The mechanism of recognition is: the color sensor TCS320 manufactured by TAOS, usa is an RGB color light-frequency converter with a digital compatible interface, which can convert the light intensity signals of three primary color components Red (Red), Green (Green) and Blue (Blue) in the color light into square wave pulse output with a frequency corresponding to the light intensity signal. The acquired pulse frequency is converted into three primary color components corresponding to the color light, and the three primary color components are processed by the microcontroller to extract characteristic parameters, so that the liquid color monitoring can be realized.
The flow measurement flow meter adopted by the multi-parameter fusion acquisition system adopts a low-frequency square wave excitation mode and a single chip microcomputer control system, the flow meter schematic diagram and the circuit structure diagram are shown in attached figures 3a and 3b, and the signal filtering, the A/D conversion diagram and the excitation driving circuit are respectively shown in attached figures 4 and 5.
Claims (7)
1. The utility model provides a many parameter thyroid gland postoperative drainage information initiative monitoring system based on internet of things, its characterized in that includes:
a drainage tube for draining fluid from the thyroid gland;
set up in drainage tube head end and arrange in thyroid bed and be used for monitoring the wireless pressure detection system of thyroid bed pressure:
the drainage liquid color intelligent identification system is used for collecting the color of the fluid in the drainage tube and analyzing the properties of the drainage liquid;
the multi-parameter fusion acquisition system is used for analyzing and counting the daily drainage quantity, the accumulated drainage quantity and the flow rate of the drainage tube;
the integration system is used for integrating the acquired pressure value, color and flow signal and sending the pressure value, color and flow signal to the mobile phone client and the computer cloud;
and an alarm system;
the drainage liquid color intelligent identification system and the multi-parameter fusion acquisition system are arranged at the relative positions of the drainage tube;
the alarm system, the wireless pressure detection system, the drainage liquid color intelligent identification system and the multi-parameter fusion acquisition system are connected with the integration system.
2. The active monitoring system for drainage information after multi-parameter thyroid surgery based on the technology of the internet of things according to claim 1, wherein the wireless pressure detection system comprises the following four parts: the implantable blood pressure monitoring device comprises an implantable wireless blood pressure sensor, an energy transmitting coil, a data reader and a data processing platform.
3. The active monitoring system for drainage information after multi-parameter thyroid surgery based on the technology of internet of things of claim 2, wherein the data reader comprises a receiving antenna, a radio frequency communication module, a special micro-processing chip and a data interface.
4. The active monitoring system for drainage information after multi-parameter thyroid surgery based on internet of things technology according to claim 1, wherein the alarm system comprises one or more of a bedside alarm system, a ward medical alarm system, and a supervisor medical mobile phone intelligent alarm system.
5. The active monitoring system for drainage information after multi-parameter thyroid surgery based on the technology of internet of things of claim 1, wherein a vertical groove is formed in the wall of the drainage tube and is located at the lower part of the wall.
6. The active monitoring system for drainage information after multi-parameter thyroid surgery based on the technology of internet of things according to claim 5, wherein a heparin coating is arranged on the surface of the drainage tube.
7. The active monitoring system for drainage information after multi-parameter thyroid surgery based on the technology of the internet of things according to claim 6, wherein a heparin coating is arranged on the surface of the drainage tube, and the heparin coating is formed according to the following method: adding 1, 1, 2-trifluorotrichloroethane and absolute ethyl alcohol into a polyethyleneimine water solution to prepare a polyethyleneimine ethanol solution, soaking a drainage tube into the polyethyleneimine ethanol solution, pouring out the residual solution after water bath, and drying at a vacuum normal temperature; pouring the heparin aqueous solution into the pipeline, so that a thin layer of white precipitate is separated out on the surface of the pipeline, pouring out the residual solution after water bath, and drying at the normal temperature in vacuum for later use.
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