CN111544296A - Blood products light energy keeps bag - Google Patents
Blood products light energy keeps bag Download PDFInfo
- Publication number
- CN111544296A CN111544296A CN202010562430.8A CN202010562430A CN111544296A CN 111544296 A CN111544296 A CN 111544296A CN 202010562430 A CN202010562430 A CN 202010562430A CN 111544296 A CN111544296 A CN 111544296A
- Authority
- CN
- China
- Prior art keywords
- bag body
- light
- blood product
- blood
- inner bag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010836 blood and blood product Substances 0.000 title claims abstract description 146
- 229940125691 blood product Drugs 0.000 title claims abstract description 146
- 238000004146 energy storage Methods 0.000 claims abstract description 40
- 239000011229 interlayer Substances 0.000 claims abstract description 20
- 238000004891 communication Methods 0.000 claims description 17
- 238000007789 sealing Methods 0.000 claims description 11
- 239000010410 layer Substances 0.000 claims description 8
- 239000000306 component Substances 0.000 abstract description 44
- 210000004369 blood Anatomy 0.000 abstract description 28
- 239000008280 blood Substances 0.000 abstract description 28
- 230000000694 effects Effects 0.000 abstract description 23
- 238000004321 preservation Methods 0.000 abstract description 23
- 230000001976 improved effect Effects 0.000 abstract description 21
- 238000011282 treatment Methods 0.000 abstract description 10
- 239000012503 blood component Substances 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 5
- 230000002035 prolonged effect Effects 0.000 abstract description 5
- 230000000638 stimulation Effects 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 3
- 238000000926 separation method Methods 0.000 abstract description 2
- 238000003860 storage Methods 0.000 description 31
- 210000003743 erythrocyte Anatomy 0.000 description 13
- 230000002829 reductive effect Effects 0.000 description 6
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- 102000008946 Fibrinogen Human genes 0.000 description 5
- 108010049003 Fibrinogen Proteins 0.000 description 5
- 229940088598 enzyme Drugs 0.000 description 5
- 229940012952 fibrinogen Drugs 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 102000001938 Plasminogen Activators Human genes 0.000 description 4
- 108010001014 Plasminogen Activators Proteins 0.000 description 4
- 230000003213 activating effect Effects 0.000 description 4
- 230000004913 activation Effects 0.000 description 4
- 230000002776 aggregation Effects 0.000 description 4
- 238000004220 aggregation Methods 0.000 description 4
- 210000000601 blood cell Anatomy 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 230000001965 increasing effect Effects 0.000 description 4
- 238000001802 infusion Methods 0.000 description 4
- 229940127126 plasminogen activator Drugs 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 238000004804 winding Methods 0.000 description 4
- 239000011324 bead Substances 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 230000002779 inactivation Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229940012957 plasmin Drugs 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000009123 Fibrin Human genes 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 238000002617 apheresis Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000002427 irreversible effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- UIURDDSZTJODOX-UHFFFAOYSA-N 1-ethenylbenzo[a]anthracene Chemical compound C1=CC=CC2=CC3=C4C(C=C)=CC=CC4=CC=C3C=C21 UIURDDSZTJODOX-UHFFFAOYSA-N 0.000 description 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- 229910001218 Gallium arsenide Inorganic materials 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000003281 allosteric effect Effects 0.000 description 1
- 102000015395 alpha 1-Antitrypsin Human genes 0.000 description 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 description 1
- 229940024142 alpha 1-antitrypsin Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000003527 fibrinolytic agent Substances 0.000 description 1
- 230000003480 fibrinolytic effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000000518 rheometry Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- JLZUZNKTTIRERF-UHFFFAOYSA-N tetraphenylethylene Chemical group C1=CC=CC=C1C(C=1C=CC=CC=1)=C(C=1C=CC=CC=1)C1=CC=CC=C1 JLZUZNKTTIRERF-UHFFFAOYSA-N 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
Abstract
The invention provides a blood product light energy storage bag, which relates to the technical field of medical equipment and comprises an inner bag body and an outer bag body. Wherein, the outer bag body is wrapped around the inner bag body. The inner space of the inner bag body is used for containing the blood product to be preserved. An interlayer is formed between the outer bag body and the inner bag body, so that a certain arrangement space is provided for the light-emitting component. The light-emitting component is arranged in the interlayer, and can emit weak light to the blood contained in the inner bag body under the power-on state, namely the weak light irradiates on the blood product. Therefore, the blood product is activated to a certain extent by utilizing the biological stimulation of weak light, so that the blood can keep certain activity, namely the activity of blood components can be maintained for a long time after the blood product is separated from a specific preservation environment, the preservation time of the blood product after separation is prolonged, the follow-up clinical medical treatment can be taken conveniently, the yield in the temporary preservation and transportation process is improved, and the treatment curative effect is improved.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a blood product light energy storage bag.
Background
With the development of economy and the intensive research of basic medicine, medical auxiliary equipment has become an indispensable role in medical treatment. In clinical medicine in particular, many operations or treatments require transfusions, which are classified as either whole blood transfusions or apheresis, depending on the blood component missing from the patient. Whether the blood transfusion is whole blood transfusion or component transfusion, the blood transfusion system needs to rely on more medical auxiliary equipment, such as a needle tube and the like in the blood collection stage; in the preservation stage, a preservation bag and the like are needed; in the transfusion phase, intravenous injection or the like is required. Because the timing of donor supply and patient demand is often difficult to match in real time, collected blood products need to be preserved for a period of time to meet the clinical needs that may arise at any time. However, as the storage time is prolonged, the blood cells in the blood product are gradually inactivated and killed, so that the clinical treatment effect is difficult to achieve. In order to improve the effect of surgery or treatment, it is necessary to improve the quality of blood products during storage as much as possible, and therefore, how to store blood products is a focus of attention in the medical field.
The existing blood products are usually placed in a transparent plastic bag and stored in a low-temperature state in a freezer to reduce the metabolism level of blood cells, and even in transportation, the blood products need to be placed in a specific storage environment which is low in temperature and light-proof, otherwise, once the blood products are separated from the specific storage environment, the blood products are easy to deteriorate due to the inactivation and death of a large amount of blood cells, so that the storage time of the blood products is short, and the blood products are inconvenient to use.
Disclosure of Invention
The present invention is directed to overcoming the above-mentioned shortcomings in the prior art, and providing a light energy storage bag for blood products, which can increase the activity of components in blood products or obtain certain quantity, property and state changes by means of low-light irradiation of blood products, thereby prolonging the storage time of blood products during storage and use, and even changing and increasing the quantity, property and function of blood components in storage according to clinical expectations and requirements.
In order to achieve the above purpose, the embodiment of the present invention adopts the following technical solutions:
in one aspect of the embodiments of the present invention, there is provided a light energy storage bag for blood products, including: an inner bag body and an outer bag body wrapped around the inner bag body; the inner bag body is used for accommodating blood products; an interlayer is formed between the outer bag body and the inner bag body, a light-emitting component is arranged in the interlayer, and the light-emitting component is used for emitting weak light towards the inner bag body.
Optionally, the blood product light energy storage bag further comprises a first connecting piece, wherein one end of the first connecting piece is connected with the outer surface of the inner bag body, and the other end of the first connecting piece is connected with the inner surface of the outer bag body.
Optionally, light emitting component is the lamp area, and the lamp area encircles the periphery setting of inner bag body.
Optionally, the lamp area includes first lamp area and second lamp area, and first lamp area is around establishing the periphery of inner bag body along the first direction, and the second lamp area is around establishing the periphery of inner bag body along the second direction, and first direction and second direction are crossing.
Optionally, the light emitting component includes a plurality of light emitting members disposed on an inner surface of the outer bag body, and the plurality of light emitting members are uniformly disposed along the inner surface of the outer bag body.
Optionally, an insulating layer is further arranged on the outer bag body.
Optionally, the inner bag body is a transparent bag body, and the outer bag body is a shading bag body.
Optionally, an observation window is further arranged on the outer bag body and close to the output end.
Optionally, the blood product light energy storage bag further comprises a storage battery, the storage battery is arranged in the interlayer, and the storage battery is electrically connected with the light emitting assembly.
Optionally, a communicating pipe is arranged on the inner bag body, the communicating pipe penetrates through the outer bag body to be communicated with the outside, and a mouth sealer is arranged at a pipe orifice of the communicating pipe.
The beneficial effects of the invention include:
the invention provides a light energy storage bag for blood products, which comprises an inner bag body and an outer bag body. Wherein, the outer bag body is sleeved on the periphery of the inner bag body. The inner space of the inner bag body is used for containing the blood product to be preserved. An interlayer is formed between the outer bag body and the inner bag body, so that a certain arrangement space is provided for the light-emitting component. The light emitting component is arranged in the interlayerUnder the power-on state, the blood product contained in the inner bag body can emit weak light, the weak light refers to irradiation light which can not cause irreversible damage when the surface of a living body is directly irradiated, the wavelength can be within 280 plus 10000nm, particularly the wavelength is commonly within 380 plus 2000nm, the power output to the irradiation part is generally 0.01-90mW/cm2By adjusting the irradiation time, the energy density can be adjusted, for example, the red light with the wavelength of 635 +/-5 nm. There is a lot of evidence that when the blood product is irradiated by weak light, the light quantum in the laser is absorbed by the components in the blood product and converted into internal energy, so as to activate the components in the blood product, and thus the blood product can maintain a certain activity in an active manner, i.e. play a certain role in delaying or blocking the inactivation tendency of blood cells, or obtain certain quantity, property and state changes. The red light can also enhance the immune function of the red blood cells. Thereby further improving the preservation quality of the blood product under the same preservation period or prolonging the preservation time of the blood product when the blood product is in the preservation environment. After the blood product is separated from the preservation environment, the activity of the components in the blood product can be maintained for a longer time, so that the preservation time of the blood product in vitro or separated from the specific preservation environment is prolonged, more treatable time is provided for clinical treatment, and the effect of operation or treatment is effectively improved. Meanwhile, the yield in the process of storage and transportation can be improved, and even the quantity, the property and the function of the blood components in the storage can be changed and improved according to clinical expectation and requirements.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic structural diagram of a blood product light energy storage bag according to an embodiment of the present invention;
fig. 2 is a second schematic structural view of a blood product light energy storage bag according to an embodiment of the present invention;
fig. 3 is a third schematic structural view of a blood product light energy storage bag according to an embodiment of the present invention;
fig. 4 is a fourth schematic structural view of a blood product light energy storage bag according to an embodiment of the present invention.
Icon: 100-an outer bag body; 101-an inner bag body; 102-a lamp strip; 1021-a first light strip; 1022-a second light strip; 103-a first connection; 104-a light emitting member; 105-communicating tube.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. It should be noted that, in the case of no conflict, various features in the embodiments of the present invention may be combined with each other, and the combined embodiments are still within the scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", etc. indicate orientations or positional relationships only for the convenience of describing the present invention and simplifying the description, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
In one aspect of the embodiments of the present invention, referring to fig. 1, there is provided a light energy storage bag for blood products, including: an inner bag body 101 and an outer bag body 100 enclosing the inner bag body 101; the inner bag body 101 is used for accommodating blood products; an interlayer is formed between the outer bag body 100 and the inner bag body 101, and a light emitting element for emitting weak light toward the inner bag body 101 is provided in the interlayer.
Illustratively, as shown in fig. 1, an outer bag body 100 is wrapped around the outer portion of an inner bag body 101, and a sandwich, i.e., a cavity, is formed between the inner and outer bag bodies. The light emitting component (i.e. the lamp strip 102 in fig. 1) is arranged in the interlayer, and the light emitting component is energized, so that the light emitting component emits weak light, and the weak light irradiates on the blood product in the inner bag body 101, and the biological stimulation effect of the weak light on the blood product is utilized, i.e. when the blood product is irradiated by the weak light, the light quantum in the laser can be absorbed by the components of the blood product and converted into internal energy, so as to activate the components of the blood product, so that the blood product can keep certain activity in an active mode, i.e. play a certain role in delaying or blocking the inactivation tendency of the components of the blood product (after the blood product is separated, the inevitable components therein die gradually). Therefore, when the blood product is in a preservation environment, the preservation quality of the blood product under the same preservation period can be further improved or the preservation time of the blood product can be prolonged, and the shortage of the quantity of the blood product in the existing blood bank can be relieved to a certain extent due to the prolongation of the preservation time. After the blood product is separated from a specific preservation environment, weak light irradiation can be continuously provided for the blood product, and the weak light is irradiated on the blood product, so that living cells in the blood product can be effectively activated and maintained, the yield of preservation and transportation of the blood product after separation can be improved, the blood product can be kept for certain activity by means of the stimulation, the preservation time is further prolonged, more treatable time is provided for clinical medical treatment, and the operation or treatment effect is effectively improved. Meanwhile, the blood product light energy storage bag in the application can be directly improved on the basis of the existing blood product storage bag, and can have related functions in the application by taking the blood product light energy storage bag as the inner bag body 101 and correspondingly arranging the outer bag body 100, the related light-emitting components and other structures on the inner bag body, so that the blood product light energy storage bag has the advantages of simple structure and low manufacturing cost, and is suitable for large-scale popularization and use.
When the blood product is irradiated by weak light, the activation of the weak light can reduce the levels of alpha 1-antitrypsin and alpha 2-globulin on the one hand, so that the fibrinolytic system is activated and the fibrinogen is reduced. Meanwhile, the chromophore, the activation and the metabolism in the blood product can be increased. Thereby effectively activating components in the blood product, such as causing the structural and functional change of cell membranes, changing the distribution of membrane enzymes, receptors and surface charges, improving the stability of the membranes and enhancing the deformability of red blood cells.
On the other hand, when the blood product is left for a long time, coagulation occurs, mainly due to the aggregation of red blood cells in the blood product. The main factors affecting the aggregation index of erythrocytes are long-chain bridging between erythrocytes and reduction of the surface charge of erythrocytes, while the main factors affecting long-chain bridging between erythrocytes are the content of fibrinogen, the more fibrinogen, the stronger the bridging between erythrocytes, and the stronger the aggregation ability of erythrocytes appears. Fibrinogen is produced primarily by the plasminogen-plasmin system, plasminogen activator is composed of a number of biological enzymes, the direction of displacement of the protein molecules is specific, the movement of the nucleolus in the protein is conformational, and rotation about a single bond requires much less energy than rotation about a long bond or changing the angle between bonds. If the electronic energy levels change, the atomic nucleus undergoes conformational movement and the electron and conformational interaction cause the enzyme to catalyze the action, so that when the frequency of laser irradiation approaches the natural frequency between certain energy levels of the plasminogen activator molecule, the electrons in the plasminogen activator molecule transition between these energy levels. Therefore, the movement of the atomic nucleus in the plasminogen activator molecule generates allosteric effect, provides power for the fractal catalysis process of enzyme, activates the plasminogen-plasmin system, decomposes more plasmin in plasma, dissolves fibrin in the plasma, reduces bridging fibrin acting between red blood cells, reduces the aggregation capability of the red blood cells, and simultaneously reduces the viscosity and the blood sedimentation of the blood. Meanwhile, because the activity of the red blood cells is increased, the immunity is improved, and the movement of the red blood cells is enhanced and is not easy to gather. Namely, the activity of the components in the blood product is effectively improved by various modes such as activating the activity of various enzymes, improving the rheology of blood, increasing the expression of related genes and the like.
It should be noted that, firstly, the above-mentioned weak light should be distinguished by the intensity of the biological effect generated after it is irradiated on the biological tissue, and based on the non-reversible damage to the target tissue (i.e. only generating positive, beneficial promoting and stimulating light to the biological tissue), its wavelength can be in 280-10000nm, especially in 380-2000nm, and its power output is in 0.01-90mw/cm2In the meantime. The laser light is not limited to stimulated emission in this application, but may be other types of light emission that emit spontaneously, etc., such as neon, fluorescent, LED, etc. For the sake of understanding, the following description will be schematically made by taking a weak laser as an example (which should not be construed as limiting the present application, and other types of light are similar to the weak laser), and the weak laser is not medically distinguished by the strength of the laser measured by the physical parameters of the laser itself, but by the strength of the biological effect generated after the laser acts on the biological tissue. The weak laser in the application refers to a weak reaction level laser which cannot cause irreversible damage to target tissues when a low-intensity laser is used for directly irradiating organisms, stimulates the organisms to generate a series of physiological and biochemical response reactions, and plays a role in regulating, enhancing or inhibiting functions, so that the aim of activating cell activity is fulfilled. The laser is different from strong laser and is characterized by low output energy and no light thermal effect, so that the local temperature rise caused by the weak laser is not more than 0.1-0.75 ℃, and the biological change of local tissues can not be caused. The weak laser usually means that the power output to the irradiated part is between 10 and 90mw, and the energy density is between 1 and 4J/cm2。
Second, the weak laser light described above may be a He-Ne laser light (wavelength at 632.8nm), a GaAlAs laser light (wavelength 820, 830nm), a GaAs laser light (wavelength 904nm), or the like. Parameters of the weak light: the wavelength is generally632.8, 820, 830 or 904 nm; the power is 10-90mw at most (a few may be less than 10mw or more than 100 mw); the waveform is continuous wave and pulse wave (1-4000 Hz); the energy density is 1-4J/cm2。
Thirdly, the light emitting module may be a He — Ne laser, a semiconductor laser, an LED lamp, or other various types.
Fourth, the inner bag body 101 and the outer bag body 100 may be both flexible bag bodies, or the inner bag body 101 may be a flexible bag body, and the outer bag body 100 may be a bag body having a certain strength, so as to protect the inner bag body 101 to a certain extent. For example, in one embodiment, the outer bag body 100 and the inner bag body 101 may be made of Polyvinyl chloride (PVC), which has the characteristics of high mechanical strength, softness and elasticity. In addition, in another embodiment, the outer bag body 100 and the inner bag body 101 may also be made of 1,1,2, 2-Tetraphenylethylene (TPE), which is mainly characterized by high elasticity, high strength and high resilience, and at the same time, the molecule mainly composed of TPE is C26H20Therefore, the paint also has the characteristics of environmental protection, no toxicity, safety, weather resistance, fatigue resistance, temperature resistance and the like. When the outer bag body 100 is a bag body with a certain strength, it may be made of polypropylene (PP), and it not only has chemical resistance and good high wear-resistant processing performance, but also has high-strength toughness, so that its finished product can have a certain strength, thereby forming a good protection capability for the inner flexible inner bag body 101.
Fifth, correspondingly, in order to further ensure the stability of the arrangement of the light emitting component, the light emitting component may be fixedly arranged or detachably arranged on the outer surface of the inner bag body 101, and may also be fixedly arranged or detachably arranged on the inner surface of the outer bag body 100.
In addition, as for the arrangement form of the light emitting component, one embodiment is as follows: the light-emitting component only contains weak light with fixed wavelength and fixed power output, and is arranged in the interlayer between the inner bag body 101 and the outer bag body 100, when a blood product is arranged in the inner bag body 101, the switch button connected with the light-emitting component can be controlled to be in an open state, so that the light-emitting component emits the weak light with the specific wavelength and the specific power output to the blood product, and the function of activating the component activity in the blood product is achieved. Because of the different blood components used in whole blood transfusions and apheresis, blood products also typically include a number of different plasma products, such as platelet products, coagulation factor products, fibrinogen products, and the like. In order to further improve the activation effect of the weak light on the blood product, the weak light which is suitable for the blood product with different components can be arranged corresponding to the blood product, so that the scientificity and flexibility of the light energy storage bag for the blood product in the application are further improved from the viewpoint of using effect. Meanwhile, different marks can be arranged on the outer surface of the outer bag body 100 of the blood product light energy storage bag corresponding to blood products with different components, for example, different colors can be used for distinguishing, and colors, symbols or fonts can be used for distinguishing, so that confusion is not easy to happen in actual use, and the use convenience is improved.
Another embodiment: the light emitting component comprises a plurality of weak light generators (which can be lamp strips 102 or lamp beads) with different wavelengths and different output powers, and the weak light generators are reasonably arranged in the interlayer (so that blood products in the inner bag body 101 can be irradiated more uniformly). Meanwhile, the outer bag body 100 can be further provided with a mode selection knob, a touch screen, a mode button and the like, and the mode selection knob, the touch screen, the mode button and the like are connected with the light-emitting component, so that the blood product light energy storage bag can flexibly select a corresponding mode according to the type of a blood product filled in the blood product light energy storage bag during use, the activation effect of the blood product light energy storage bag can be improved, and the use range and the automation degree of the blood product light energy storage bag can be improved. The following description will be schematically made in the form of a mode selection knob, which corresponds to both a mode and B mode, and may be provided with an off mode, i.e., an off power-off mode. In use, the corresponding mode may be selected according to the type of blood product loaded. In addition, four modes, five modes and the like (the same as the three modes) can be provided, so that the blood product light energy storage bag can support more blood products with different components. In order to further reduce the manufacturing and using cost, the outer bag body 100 and the inner bag body 101 may be detachably connected (for example, by using a connection method such as a zipper or a velcro tape), so that the manufacturing and using cost is reduced by using the outer bag body 100 and the light emitting element for many times.
Optionally, the blood product light energy storage bag further comprises a first connecting member 103, wherein one end of the first connecting member 103 is connected with the outer surface of the inner bag body 101, and the other end is connected with the inner surface of the outer bag body 100.
For example, referring to fig. 2, a first connecting member 103 is further disposed in the interlayer, and the inner bag body 101 is connected to the outer bag body 100 through the first connecting member 103, so that a certain connection relationship can be formed between the inner bag body and the outer bag body, and mutual rotation between the inner bag body 101 and the outer bag body 100 can be effectively prevented, thereby avoiding occurrence of phenomena such as winding and dislocation. Simultaneously, also can make the weak light that light emitting component sent more stable to blood products's shining, avoid at transportation etc. in-process, because of taking place to rotate between the interior outer bag body for the weak light that light emitting component sent is difficult to effectual shining blood products. The stability of the light energy storage bag for blood products in the embodiment when the blood products are stored is improved, namely the yield of the blood products in transportation or use is improved. It should be noted that the form of the first connecting member 103 may be various, and the present application does not specifically limit the form, and two of them will be schematically given below by way of example:
as shown in fig. 2, when the first connecting member 103 is a glue column, a plurality of glue columns may be disposed in the interlayer, the setting position may be as shown in fig. 2, only one circle is disposed between the inner bag body 101 and the outer bag body 100, this setting form can effectively save raw materials, reduce manufacturing cost, and is suitable for a scene with a weak vibration environment, for example, blood collection is performed in a blood donation point, and after the blood collection is completed, the light energy blood product storage bag in the present application is placed in a low temperature environment of a blood bank of a blood station for storage, so as to facilitate subsequent use. Simultaneously, the position of setting can also be along the surface equipartition setting of inner bag body 101 to make the inner bag body all can form even restriction through the connection of gluing the post in every position, reduce the relative rocking between the two bag bodies, be applicable to the stronger scene of vibration environment, for example, after gathering the completion, place it in the place that accords with the regulation earlier and preserve, but when needs transport afterwards, then need longer distance's transportation, can strengthen the intensity of the bag body, further improvement blood products is the yield in the transportation.
The inner bag 101 of the present invention may be a conventional blood storage bag, and a transparent bag is generally used. Meanwhile, the outer bag body 100 may be configured as a foldable bag body, and the specific folding form may be that one side has an opening, or that three sides have openings (in this form, when folded, the fourth side may be used as a rotation center to completely unfold the two opposite side walls of the outer bag body 100), and then the existing blood storage bag is placed therein, and the side of the outer bag body 100 where the opening is provided is closed, thereby realizing the irradiation of weak light. The convenience in use is further improved, and the cost in use can be effectively reduced.
In addition, the first connecting member 103 may also be a protrusion disposed on the inner wall of the outer bag body 100 and a groove disposed on the outer wall of the inner bag body 101, respectively, so that the outer bag body 100 and the inner bag body 101 form a stable connection relationship by performing interference fit with the protrusion and the groove. Meanwhile, the inner bag body 101 and the outer bag body 100 can be conveniently detached when needed. Optionally, the light emitting component is a light strip 102, and the light strip 102 is disposed around the periphery of the inner bag 101.
For example, as shown in fig. 1, the light emitting component may be a light strip 102, that is, weak light is emitted by using a linear light source, and in order to enable the light strip 102 to have a good biological stimulation effect on the blood product in the inner bag 101, the light strip 102 may be disposed in a manner of surrounding the periphery of the inner bag 101. Thereby ensuring that the blood product in the inner bag body 101 can be well irradiated by weak light all the time. The manner in which the light strip 102 surrounds the inner bag 101 is not particularly limited, and may be, for example, a spiral winding, or a manner in which a plurality of annular strips are wound in the following embodiments. As long as it ensures that the blood product is constantly illuminated with a low level of light.
Optionally, the light strip 102 includes a first light strip 1021 and a second light strip 1022, where the first light strip 1021 is disposed around a periphery of the inner bag 101 along a first direction, and the second light strip 1022 is disposed around a periphery of the inner bag 101 along a second direction, where the first direction and the second direction intersect.
As an example, the light strip 102 may further include a plurality of light strips, wherein the first light strip 1021 is disposed around the periphery of the inner bag 101 along a first direction, as shown in fig. 3, when the first light strip 1021 is disposed in a spiral winding manner, only one light strip may be disposed, in order to further improve the uniformity of the weak light irradiation, the second light strip 1022 may also be disposed as one light strip, directions in which the two light strips 102 extend in a spiral manner intersect, so as to form uniform weak light irradiation on the blood product in the inner bag 101 in a crossed structure manner, wherein, in order to ensure the full irradiation, both the starting end and the ending end of the first light strip 1021 and the second light strip 1022 should be disposed at positions at both ends of the inner bag 101. In this embodiment, can also make the inner bag body 101 be current blood bag (current blood bag is a bag body similar to infusion bag, and generally be transparent plastic material), make up it with the outer bag body 100, for the convenient change of the reuse rate of the further improvement outer bag body 100 and the inner bag body 101, can all set up first lamp area 1021 and second lamp area 1022 on the inner wall of the outer bag body 100, but the position that sets up of first lamp area 1021 and second lamp area 1022, the light-emitting direction all corresponds with the blood goods in the inner bag body 101. Therefore, the yield of blood products can be improved, the manufacturing cost of the blood product light energy storage bag can be effectively reduced, and the blood product light energy storage bag can be conveniently applied on a large scale.
When the ring-shaped winding is performed in the manner shown in fig. 1, in order to ensure that the blood product inside the inner bag body 101 can be uniformly irradiated by weak light, a plurality of first light strips 1021 may be provided and may be arranged in parallel with each other. Similarly, the second light strip 1022 may also be provided with a plurality of strips, which are arranged in parallel. And the corresponding first light strip 1021 and second light strip 1022 are perpendicular (not shown), so as to form a grid-like illumination structure (refer to the grid-like structure in which the first direction and the second direction intersect in fig. 3), which meets the requirement of the blood product on uniform weak light illumination. Meanwhile, when the inner bag body 101 is an existing blood bag, the first light strip 1021 and the second light strip 1022 may be disposed on the inner wall of the outer bag body 100, and the setting requirements refer to the requirements of the spiral setting.
Optionally, the light emitting assembly includes a plurality of light emitting members 104 disposed on the inner surface of the outer bag body 100, and the plurality of light emitting members 104 are uniformly disposed along the inner surface of the outer bag body 100.
For example, as shown in fig. 4, the light emitting component may also be a plurality of light emitting elements 104 disposed on the inner surface (i.e., inner wall) of the outer bag 100, that is, emitting weak light in a manner of a point light source, such as an LED light. The inner bag body 101 and the outer bag body 100 are integrated together, so that the space required by an interlayer can be reduced, the space utilization rate of the inner bag body 101 is improved, and the volume of the light energy storage bag for blood products is effectively reduced. Meanwhile, when the outer bag body 100 is a flexible bag body, the flexibility thereof may not be affected as much as possible. In order to make the blood product stored in the inner bag 101 uniformly and stably irradiated by weak light, a plurality of LED light beads may be uniformly arranged on the inner wall of the outer bag 100, so that the LED light beads can emit the same weak light to the inner bag 101 from various angles in the power-on state. It should be noted that the light emitting element 104 may be disposed on a side wall of the inner wall of the outer bag body 100, and the side wall on which the light emitting element 104 is disposed should be placed downward when in use, that is, the blood product light energy storage bag is turned over by 180 degrees in fig. 4, so that the weak light is irradiated from the bottom upward, thereby facilitating the uniform light reception of the blood. In addition, the light emitting members 104 may be disposed on both inner walls of the outer bag 100.
Optionally, an insulating layer is further disposed on the outer bag body 100.
For example, in order to further improve the yield and the preservation time of the blood product, an insulating layer may be disposed on the outer bag body 100, so that the inner bag body 101 enclosed in the outer bag body 100 is at a suitable temperature for preservation as much as possible, and the preservation time of the blood product may be effectively improved by combining the weak light irradiation in the foregoing embodiment. It should be noted that the heat-insulating layer may be made of the heat-insulating material of the outer bag body 100 itself, or may be formed by providing a heat-insulating structure layer on the outer wall of the outer bag body 100, or by providing a heat-insulating structure layer on the inner wall of the outer bag body 100, or by providing both sides of the outer bag body 100.
Optionally, the inner bag body 101 is a transparent bag body, and the outer bag body 100 is a light-shielding bag body.
For example, in order to further increase the irradiation area of the inner bag 101 so that the weak light can provide stable irradiation to the blood product at each position, the inner bag 101 may be a transparent bag (i.e., a transparent material through which light can pass). In order to avoid deterioration of the blood product caused by direct irradiation of external light, the outer bag body 100 can be further configured as a light-shielding bag body (i.e., an opaque material), so that the biological stimulation of weak light can be utilized to prolong the storage time of the blood product in the inner bag body 101, and the influence of external environment light on the inner bag body can be avoided. It should be noted that, in this embodiment, the inner bag body 101 may be an existing blood bag, and the inner bag body may be combined with the light-shielding outer bag body 100 (the first connecting member 103, the light strip 102, the light-emitting member 104, and the like in other embodiments may be provided), so as to improve the yield of blood products and the application range of the light-energy blood product storage bag in this embodiment. Meanwhile, besides the outer bag body 100 is made of opaque materials, a light shielding layer can be arranged on the outer bag body 100 and can reflect light or absorb light, and therefore the purpose of shielding light is achieved.
Optionally, an observation window is further disposed on the outer bag body 100 near the output end.
For example, an observation window may be further disposed on the light-shielding outer bag body 100, so that a medical care worker or an operator can observe the related state information of the blood product in the inner bag body 101 through the observation window from the outside, for example, the remaining amount of the blood product in the inner bag body 101 is observed through the observation window, or whether the color of the blood product in the inner bag body 101 is normal is observed through the observation window, and whether the blood product has a sign of deterioration is preliminarily determined. The observation window can be in the form of a hollow window, can be in the shape of a square, a rectangle, a circle and the like, and can be 0.5 square centimeter, 1 square centimeter and the like in size; the observation window can also be by the region of fretwork and with the cover plate of the transparent material of the regional size matching of fretwork and constitute, both form the sealed of outer bag body 100 inside supporting, strengthen its dustproof and waterproof ability. In addition, in order to control the state of the blood bag in use, and because the output end of the blood bag faces downwards in use, the blood product in the inner bag body 101 is fed into the patient body through the output end via the infusion tube, the observation window can be arranged at one side close to the output end, so that the remaining amount of the blood product in the blood product light energy storage bag can be conveniently controlled. The specific position, size and specific form of the observation window are not limited in the application.
Optionally, the blood product light energy storage bag further comprises a storage battery, the storage battery is arranged in the interlayer, and the storage battery is electrically connected with the light emitting assembly.
For example, a storage battery may be disposed in an interlayer between the inner bag body 101 and the outer bag body 100, and the storage battery is electrically connected to the light emitting assembly, so as to supply power to the light emitting assembly under certain conditions. In addition, a switch can be arranged between the storage battery and the light-emitting component, and whether the light-emitting component emits weak light or not can be controlled by controlling the on and off of the switch. Meanwhile, the control switch can also be an adjusting switch, so that the light-emitting component is controlled to emit weak light with different powers by adjusting the position of the switch. The storage battery may be a rechargeable storage battery, and the outer bag body 100 is provided with a charging interface electrically connected to the rechargeable storage battery, so that the storage battery can be directly charged externally when necessary. Avoiding the complex operation of frequently replacing the storage battery.
Optionally, a communication pipe 105 is provided on the inner bag body 101, the communication pipe 105 passes through the outer bag body 100 to communicate with the outside, and a sealing device is provided at a nozzle of the communication pipe 105.
As shown in fig. 4, a communication pipe 105 may be further disposed on the inner bag 101, one end of the communication pipe 105 is communicated with the inner space of the inner bag 101, and the other end is communicated with the outside, that is, a structural form is formed in which one end of the communication pipe 105 extends into the inner bag 101, and the other end passes through the interlayer between the outer bag 100 and the inner bag 101 and the bag wall of the body of the outer bag 100. In order to ensure the sealing property of the internal space of the inner bag 101, a sealing device may be provided at a nozzle at one end of the communication pipe 105 communicating with the outside. The sealing device may be made of medical grade polyvinyl chloride (PVC), or may be made of medical rubber, and may be coated on the outer wall of the communication pipe 105, or may be filled in the inner passage of the communication pipe 105.
In actual use, when a blood product needs to be introduced into the inner bag 101, the operator first takes the sealing device at the nozzle of the communication pipe 105 off, then communicates the end of the communication pipe 105 communicating with the outside with the blood product, guides the blood product to flow into the space inside the inner bag 101 through the pipe of the communication pipe 105, and finally installs the sealing device at the nozzle, thereby completely sealing the inner space of the inner bag 101. When the blood product needs to be output to the outside, the infusion tube can be directly inserted into the sealing device, so that the blood in the inner bag body 101 can be output to the outside through the infusion tube. The sealer may be removed from the opening of the communication pipe 105 and then output to the outside. By arranging the communication pipe 105 and the sealing device, the operator can conveniently input the blood product into the inner bag body 101 or output the blood product in the inner bag body 101 to the outside, and the good sealing performance of the blood product in the inner bag body 101 can be further ensured.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A blood product light energy storage bag, comprising: the inner bag body and the outer bag body are wrapped on the inner bag body; the inner bag body is used for accommodating blood products; an interlayer is formed between the outer bag body and the inner bag body, a light-emitting component is arranged in the interlayer, and the light-emitting component is used for emitting weak light towards the inner bag body.
2. The blood product light energy storage bag of claim 1, further comprising a first connector, wherein one end of the first connector is connected to the outer surface of the inner bag body and the other end of the first connector is connected to the inner surface of the outer bag body.
3. The blood product light energy storage bag of claim 1, wherein the light emitting component is a light strip disposed around a periphery of the inner bag body.
4. The blood product light energy storage bag of claim 3, wherein said light strip comprises a first light strip disposed around a periphery of said inner bag body in a first direction and a second light strip disposed around a periphery of said inner bag body in a second direction, said first direction and said second direction intersecting.
5. The blood product light energy storage bag of claim 1, wherein said light emitting assembly comprises a plurality of light emitting members disposed on an inner surface of said outer bag body, said plurality of light emitting members being disposed uniformly along an inner surface of said outer bag body.
6. The blood product light energy storage bag according to claim 1, wherein an insulating layer is further provided on the outer bag body.
7. A blood product light energy storage bag according to any one of claims 1 to 6, wherein the inner bag body is a transparent bag body, and the outer bag body is a light-shielding bag body.
8. The blood product light energy storage bag of claim 7, wherein a viewing window is further provided on said outer bag body adjacent to said outlet end.
9. The blood product light energy storage bag of any one of claims 1 to 6, further comprising a battery disposed within the interlayer, the battery being electrically connected to the light emitting assembly.
10. A blood product light energy storage bag according to any one of claims 1 to 6, wherein a communication pipe is provided on the inner bag body, the communication pipe passes through the outer bag body to communicate with the outside, and a sealing device is provided at a nozzle of the communication pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010562430.8A CN111544296B (en) | 2020-06-18 | 2020-06-18 | Light energy storage bag for blood products |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010562430.8A CN111544296B (en) | 2020-06-18 | 2020-06-18 | Light energy storage bag for blood products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111544296A true CN111544296A (en) | 2020-08-18 |
| CN111544296B CN111544296B (en) | 2024-03-12 |
Family
ID=71999531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010562430.8A Active CN111544296B (en) | 2020-06-18 | 2020-06-18 | Light energy storage bag for blood products |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111544296B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113736173A (en) * | 2021-07-28 | 2021-12-03 | 上海乐纯生物技术有限公司 | Cell therapy liquid storage bag and manufacturing method thereof |
Citations (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038312A1 (en) * | 1980-04-10 | 1981-10-21 | Vitrum Ab | Package |
| GB8333774D0 (en) * | 1982-12-20 | 1984-01-25 | El Paso Polyolefins | Heat-sterilisable polyolefins compositions |
| US4561110A (en) * | 1982-01-07 | 1985-12-24 | Fresenius Ag | Bag for the storage of liquids |
| US4830205A (en) * | 1987-01-21 | 1989-05-16 | Mb Group, Plc | Baby feeding packs |
| JPH02255601A (en) * | 1989-03-29 | 1990-10-16 | Kawasumi Lab Inc | Method for preserving blood platelet |
| CN2072837U (en) * | 1990-07-23 | 1991-03-13 | 刘余厚 | One-way blood container used for ultraviolet radiation blood therapy |
| JPH0437436U (en) * | 1990-07-27 | 1992-03-30 | ||
| JPH05317382A (en) * | 1992-05-14 | 1993-12-03 | Hitachi Medical Corp | Method for indicating that bag for retaining blood for transfusion has been exposed to radiation and bag for retaining blood for transfusion equipped with indication of exposure to radiation |
| CN2149208Y (en) * | 1992-12-01 | 1993-12-15 | 刘佘厚 | Light quantum irradiation treating blood bag |
| JPH0678968A (en) * | 1992-08-31 | 1994-03-22 | Kawasumi Lab Inc | Medical bag |
| JPH0690992A (en) * | 1992-09-11 | 1994-04-05 | Hitachi Medical Corp | Method for displaying 'radiation exposed' of blood preserving bag for transfusion and blood preserving bag for transfusion with 'radiaiton exposed' display |
| DE4410411A1 (en) * | 1994-03-25 | 1995-10-05 | Hans Mueller | Extracorporeal blood treatment appts. with soft plastic container |
| RU2103035C1 (en) * | 1993-12-10 | 1998-01-27 | Игнатенко Александр Георгиевич | Device for ultraviolet irradiation of blood |
| US6059820A (en) * | 1998-10-16 | 2000-05-09 | Paradigm Medical Corporation | Tissue cooling rod for laser surgery |
| US6245570B1 (en) * | 1991-05-08 | 2001-06-12 | Baxter International Inc. | Container for irradiation of blood products |
| US20030072676A1 (en) * | 2001-09-27 | 2003-04-17 | Peter Fletcher-Haynes | Radio frequency of electromagnetic information systems and methods for use in extracorporeal blood processing |
| US20030219354A1 (en) * | 2000-06-15 | 2003-11-27 | Hlavinka Dennis J. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
| US20040132002A1 (en) * | 2002-09-17 | 2004-07-08 | Jackson Streeter | Methods for preserving blood |
| JP2006182408A (en) * | 2004-12-28 | 2006-07-13 | Toyo Seikan Kaisha Ltd | Sterile double chamber type retort pouch and its sterilization method |
| US20070032774A1 (en) * | 2005-05-17 | 2007-02-08 | Clifford Glade | Container for transporting blood and blood products |
| DE102005062410A1 (en) * | 2005-12-23 | 2007-08-09 | Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. | Method for irradiating platelet concentrates in flexible containers with ultraviolet light |
| JP2007296170A (en) * | 2006-05-01 | 2007-11-15 | Masahito Makino | Blood product container |
| US20090088709A1 (en) * | 2007-09-27 | 2009-04-02 | Salvadori Lawrence A | Illuminated fluid collection bag |
| CN101564350A (en) * | 2008-04-23 | 2009-10-28 | 丽珠集团利民制药厂 | Soft package of instantaneous matching type medical inner bag with a plurality of chambers |
| US20100133203A1 (en) * | 2006-09-19 | 2010-06-03 | Wolfram Hubert Walker | Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system |
| CN202283371U (en) * | 2011-10-25 | 2012-06-27 | 傅其银 | Blood bag for internal radiation hemotherapy |
| US20130281964A1 (en) * | 2012-04-23 | 2013-10-24 | Fresenius Medical Care Deutschland Gmbh | Bag with a flexurally rigid plastic part welded into it |
| US20140158604A1 (en) * | 2012-12-12 | 2014-06-12 | Jacques Chammas | Platelet Storage Container |
| CN204072915U (en) * | 2014-10-11 | 2015-01-07 | 张�雄 | A kind of Multifunctional full spectrum tachometer system |
| CN104403122A (en) * | 2014-11-12 | 2015-03-11 | 无锡中科光远生物材料有限公司 | Blood stabilizer, blood bag and preparation method thereof |
| CN204582023U (en) * | 2015-03-18 | 2015-08-26 | ***广州总医院 | A kind of plaque virus inactivating device |
| CN204670015U (en) * | 2015-06-11 | 2015-09-30 | 澄迈绿青林农业开发有限公司 | A kind of double-deck fruit bagging |
| CN204840280U (en) * | 2015-07-29 | 2015-12-09 | 江苏善之源健康科技有限公司 | Novel anti -freezing blood sampling bag |
| US20150375404A1 (en) * | 2013-02-20 | 2015-12-31 | Toyota Jidosha Kabushiki Kaisha | Gripping device |
| CN105480572A (en) * | 2015-12-19 | 2016-04-13 | 北海恒科电子配件有限公司 | Packing cushion layer capable of detecting leakage automatically |
| CN105561359A (en) * | 2016-02-02 | 2016-05-11 | 汪相伯 | Blood product treatment system based on riboflavin photochemical method |
| US20160213566A1 (en) * | 2015-01-26 | 2016-07-28 | Fresenius Kabi Deutschland Gmbh | Container closure system |
| WO2017133422A1 (en) * | 2016-02-02 | 2017-08-10 | 汪相伯 | Blood product processing system on the basis of riboflavin photochemical treatment |
| US20170239404A1 (en) * | 2014-08-08 | 2017-08-24 | Fremon Scientific, Inc. | Smart Bag Used in Sensing Physiological and/or Physical Parameters of Bags Containing Biological Substance |
| CN107456615A (en) * | 2017-09-18 | 2017-12-12 | 佛山迅拓奥科技有限公司 | A kind of blood insulation preserves equipment |
| JP2018047919A (en) * | 2016-09-20 | 2018-03-29 | サッポロビール株式会社 | Soft packaging container |
| EP3301010A1 (en) * | 2016-09-29 | 2018-04-04 | Bernhardt Apparatebau GmbH u. Co. | Inflatable float with leak indicator |
| US20190099543A1 (en) * | 2016-03-23 | 2019-04-04 | Terumo Kabushiki Kaisha | Light irradiation device |
-
2020
- 2020-06-18 CN CN202010562430.8A patent/CN111544296B/en active Active
Patent Citations (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0038312A1 (en) * | 1980-04-10 | 1981-10-21 | Vitrum Ab | Package |
| US4411358A (en) * | 1980-04-10 | 1983-10-25 | Vitrum Ab | Package |
| US4561110A (en) * | 1982-01-07 | 1985-12-24 | Fresenius Ag | Bag for the storage of liquids |
| GB8333774D0 (en) * | 1982-12-20 | 1984-01-25 | El Paso Polyolefins | Heat-sterilisable polyolefins compositions |
| US4830205A (en) * | 1987-01-21 | 1989-05-16 | Mb Group, Plc | Baby feeding packs |
| JPH02255601A (en) * | 1989-03-29 | 1990-10-16 | Kawasumi Lab Inc | Method for preserving blood platelet |
| CN2072837U (en) * | 1990-07-23 | 1991-03-13 | 刘余厚 | One-way blood container used for ultraviolet radiation blood therapy |
| JPH0437436U (en) * | 1990-07-27 | 1992-03-30 | ||
| US6245570B1 (en) * | 1991-05-08 | 2001-06-12 | Baxter International Inc. | Container for irradiation of blood products |
| JPH05317382A (en) * | 1992-05-14 | 1993-12-03 | Hitachi Medical Corp | Method for indicating that bag for retaining blood for transfusion has been exposed to radiation and bag for retaining blood for transfusion equipped with indication of exposure to radiation |
| JPH0678968A (en) * | 1992-08-31 | 1994-03-22 | Kawasumi Lab Inc | Medical bag |
| JPH0690992A (en) * | 1992-09-11 | 1994-04-05 | Hitachi Medical Corp | Method for displaying 'radiation exposed' of blood preserving bag for transfusion and blood preserving bag for transfusion with 'radiaiton exposed' display |
| CN2149208Y (en) * | 1992-12-01 | 1993-12-15 | 刘佘厚 | Light quantum irradiation treating blood bag |
| RU2103035C1 (en) * | 1993-12-10 | 1998-01-27 | Игнатенко Александр Георгиевич | Device for ultraviolet irradiation of blood |
| DE4410411A1 (en) * | 1994-03-25 | 1995-10-05 | Hans Mueller | Extracorporeal blood treatment appts. with soft plastic container |
| US6059820A (en) * | 1998-10-16 | 2000-05-09 | Paradigm Medical Corporation | Tissue cooling rod for laser surgery |
| US20030219354A1 (en) * | 2000-06-15 | 2003-11-27 | Hlavinka Dennis J. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
| US20030072676A1 (en) * | 2001-09-27 | 2003-04-17 | Peter Fletcher-Haynes | Radio frequency of electromagnetic information systems and methods for use in extracorporeal blood processing |
| US20040132002A1 (en) * | 2002-09-17 | 2004-07-08 | Jackson Streeter | Methods for preserving blood |
| JP2006182408A (en) * | 2004-12-28 | 2006-07-13 | Toyo Seikan Kaisha Ltd | Sterile double chamber type retort pouch and its sterilization method |
| US20070032774A1 (en) * | 2005-05-17 | 2007-02-08 | Clifford Glade | Container for transporting blood and blood products |
| DE102005062410A1 (en) * | 2005-12-23 | 2007-08-09 | Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. | Method for irradiating platelet concentrates in flexible containers with ultraviolet light |
| NZ569429A (en) * | 2005-12-23 | 2011-09-30 | Forschungsgemeinschaft Der Drk Blutspendedienste E V | Method for irradiating thrombocyte concentrates in flexible containers with ultraviolet light to destroy pathogens and leucocytes |
| JP2007296170A (en) * | 2006-05-01 | 2007-11-15 | Masahito Makino | Blood product container |
| US20100133203A1 (en) * | 2006-09-19 | 2010-06-03 | Wolfram Hubert Walker | Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system |
| US20090088709A1 (en) * | 2007-09-27 | 2009-04-02 | Salvadori Lawrence A | Illuminated fluid collection bag |
| CN101564350A (en) * | 2008-04-23 | 2009-10-28 | 丽珠集团利民制药厂 | Soft package of instantaneous matching type medical inner bag with a plurality of chambers |
| CN202283371U (en) * | 2011-10-25 | 2012-06-27 | 傅其银 | Blood bag for internal radiation hemotherapy |
| US20130281964A1 (en) * | 2012-04-23 | 2013-10-24 | Fresenius Medical Care Deutschland Gmbh | Bag with a flexurally rigid plastic part welded into it |
| US20140158604A1 (en) * | 2012-12-12 | 2014-06-12 | Jacques Chammas | Platelet Storage Container |
| US20150375404A1 (en) * | 2013-02-20 | 2015-12-31 | Toyota Jidosha Kabushiki Kaisha | Gripping device |
| US20170239404A1 (en) * | 2014-08-08 | 2017-08-24 | Fremon Scientific, Inc. | Smart Bag Used in Sensing Physiological and/or Physical Parameters of Bags Containing Biological Substance |
| CN204072915U (en) * | 2014-10-11 | 2015-01-07 | 张�雄 | A kind of Multifunctional full spectrum tachometer system |
| CN104403122A (en) * | 2014-11-12 | 2015-03-11 | 无锡中科光远生物材料有限公司 | Blood stabilizer, blood bag and preparation method thereof |
| US20160213566A1 (en) * | 2015-01-26 | 2016-07-28 | Fresenius Kabi Deutschland Gmbh | Container closure system |
| CN204582023U (en) * | 2015-03-18 | 2015-08-26 | ***广州总医院 | A kind of plaque virus inactivating device |
| CN204670015U (en) * | 2015-06-11 | 2015-09-30 | 澄迈绿青林农业开发有限公司 | A kind of double-deck fruit bagging |
| CN204840280U (en) * | 2015-07-29 | 2015-12-09 | 江苏善之源健康科技有限公司 | Novel anti -freezing blood sampling bag |
| CN105480572A (en) * | 2015-12-19 | 2016-04-13 | 北海恒科电子配件有限公司 | Packing cushion layer capable of detecting leakage automatically |
| CN105561359A (en) * | 2016-02-02 | 2016-05-11 | 汪相伯 | Blood product treatment system based on riboflavin photochemical method |
| WO2017133422A1 (en) * | 2016-02-02 | 2017-08-10 | 汪相伯 | Blood product processing system on the basis of riboflavin photochemical treatment |
| US20190099543A1 (en) * | 2016-03-23 | 2019-04-04 | Terumo Kabushiki Kaisha | Light irradiation device |
| JP2018047919A (en) * | 2016-09-20 | 2018-03-29 | サッポロビール株式会社 | Soft packaging container |
| EP3301010A1 (en) * | 2016-09-29 | 2018-04-04 | Bernhardt Apparatebau GmbH u. Co. | Inflatable float with leak indicator |
| CN107456615A (en) * | 2017-09-18 | 2017-12-12 | 佛山迅拓奥科技有限公司 | A kind of blood insulation preserves equipment |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113736173A (en) * | 2021-07-28 | 2021-12-03 | 上海乐纯生物技术有限公司 | Cell therapy liquid storage bag and manufacturing method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111544296B (en) | 2024-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN202078655U (en) | Photodynamic therapy equipment for living organism tissues | |
| CN102844075B (en) | Scalar device for laser therapy | |
| CN111544296A (en) | Blood products light energy keeps bag | |
| CN108136196A (en) | For the system and method adjusted to nitric oxide production phototherapy | |
| KR20150126817A (en) | Phototherapy system and process including dynamic led driver with programmable waveform | |
| KR102135544B1 (en) | Air cleaner | |
| US8236037B2 (en) | Scalar laser therapy apparatus | |
| CN106581862B (en) | Biological field leads special seedling | |
| Ye et al. | Optogenetic medicine: synthetic therapeutic solutions precision-guided by light | |
| CN103211377A (en) | LED (Light-Emitting Diode) multiple-wavelength photon comb | |
| CN202151465U (en) | Millimeter wave therapeutic instrument system | |
| CN105617541B (en) | Laser and its control method Internet-based | |
| CN207016500U (en) | Spin quantizing resonance cup | |
| CN102000393A (en) | LED (light-emitting diode)-based portable treatment device transmitting 670nm red light | |
| US20150297915A1 (en) | Apparatus for maintaining treatment of peripheral neuropathy | |
| CN209548518U (en) | Collagen regeneration instrument and its work head | |
| CN209075552U (en) | A kind of sterilization bag with charger baby function | |
| CN218737601U (en) | Woman bag with sterilization and disinfection functions | |
| WO2020227740A1 (en) | Potable liquid container | |
| CN217366099U (en) | Intelligent 5G positioning mobile nursing health bag | |
| CN219374934U (en) | Sugar control box | |
| CN110192976A (en) | A kind of the medical and beauty treatment method and consumptive material of Oxygen Generator oxygen supply | |
| CN207855985U (en) | A kind of portable medical sterilizing equipment decontaminating apparatus | |
| CN212545989U (en) | Folding UV disinfection package that disinfects | |
| KR102650028B1 (en) | Mask device for facial skin care in which the inner mask is made of graphene composite material |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |