CN111529680A

CN111529680A - Traditional Chinese medicine preparation for treating bradycardia

Info

Publication number: CN111529680A
Application number: CN202010577725.2A
Authority: CN
Inventors: 王思佳
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-06-23
Filing date: 2020-06-23
Publication date: 2020-08-14
Anticipated expiration: 2040-06-23
Also published as: CN111529680B

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine preparation for treating bradycardia, which comprises the following raw materials by weight: 10-30g of dried ginger, 10-30g of black shun tablet, 10-30g of allium macrostemon, 10-30g of inula flower, 10-30g of cassia twig, 10-30g of storax, 10-30g of halloysite, 10-30g of ginkgo leaf, 10-30g of dark plum, 10-30g of zanthoxylum piperitum, 10-30g of salvia miltiorrhiza, 10-30g of ligusticum wallichii, 10-30g of semen lepidii, 10-30g of cortex acanthopanacis, 10-30g of rhizoma corydalis, 10-30g of radix angelicae, 10-30g of schisandra chinensis, 10-30g of hedysarum polybotrys, 10-30g of coptis chinensis and 10-30g of liquorice. Through the technical scheme, the problem of poor curative effect of the traditional Chinese medicine for treating bradycardia in the prior art is solved.

Description

Traditional Chinese medicine preparation for treating bradycardia

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine preparation for treating bradycardia.

Background

Bradycardia, which means heart rate of less than 60 times/min, can be seen in normal people, athletes, old people and deep sleep, and can cause sudden palpitation and slow heartbeat with arrhythmia, and can be expressed as amaurosis, paroxysmal dizziness, syncope, even sudden death, and bradycardia which lasts for a long time and occurs slowly, even no symptom. Bradycardia belongs to the range of ' palpitation ' and ' severe palpitation ' in traditional Chinese medicine, and the picture of paradox is formally named ' palpitation ' in ' jin Kui Yao L ü e, and there are records that ' palpitations occurs immediately and palpitations occurs when weak '. Common causes are arrhythmia, cardiomyopathy, cervical trauma, hypothermia, hypothyroidism, increased intracranial pressure, myocardial infarction, transient bradycardia, hypoxemia, vagus nerve stimulation, tissue edema, injury, etc., and particularly heart rate <40 times/min, possibly even slower, due to cardiovascular system diseases.

For the treatment of bradycardia, currently available means are: firstly, an artificial pacemaker is installed, and because the cost is high and the service life is short, the artificial pacemaker cannot become a preferred treatment scheme for patients at present; secondly, the method for treating by adopting western medicines comprises the following steps: atropine, isoproterenol, ephedrine and the like are temporarily used under the condition of no pacing, but cannot be cured fundamentally, the relapse rate is high after the medicine is stopped, and adverse reactions and side effects are great; thirdly, the traditional Chinese medicine is adopted for treatment, but the actual curative effect is not ideal.

Disclosure of Invention

The invention provides a traditional Chinese medicine preparation for treating bradycardia, and solves the problem that traditional Chinese medicines for treating bradycardia in the prior art are poor in curative effect.

The technical scheme of the invention is realized as follows: a traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 10-30g of dried ginger, 10-30g of black shun tablet, 10-30g of allium macrostemon, 10-30g of inula flower, 10-30g of cassia twig, 10-30g of storax, 10-30g of halloysite, 10-30g of ginkgo leaf, 10-30g of dark plum, 10-30g of zanthoxylum piperitum, 10-30g of salvia miltiorrhiza, 10-30g of ligusticum wallichii, 10-30g of semen lepidii, 10-30g of cortex acanthopanacis, 10-30g of rhizoma corydalis, 10-30g of radix angelicae, 10-30g of schisandra chinensis, 10-30g of hedysarum polybotrys, 10-30g of coptis chinensis and 10-30g of liquorice.

Preferably, the feed comprises the following raw materials by weight: 20-30g of dried ginger, 20-30g of black shun tablet, 10-20g of allium macrostemon, 15-30g of inula flower, 10-25g of cassia twig, 15-30g of storax, 20-30g of halloysite, 10-25g of ginkgo leaf, 15-30g of dark plum, 10-25g of zanthoxylum piperitum, 15-30g of salvia miltiorrhiza, 15-30g of ligusticum wallichii, 10-25g of semen lepidii, 15-30g of acanthopanax bark, 15-30g of rhizoma corydalis, 10-20g of radix angelicae, 18-30g of schisandra chinensis, 12-30g of hedysarum polybotrys, 16-30g of coptis chinensis and 10-25g of liquorice.

Preferably, the feed comprises the following raw materials by weight: 20-25g of dried ginger, 20-28g of black shun tablet, 10-18g of allium macrostemon, 15-23g of inula flower, 10-20g of cassia twig, 15-24g of storax, 20-27g of halloysite, 10-21g of ginkgo leaf, 15-25g of dark plum, 10-22g of zanthoxylum piperitum, 15-20g of salvia miltiorrhiza, 15-26g of ligusticum wallichii, 10-21g of semen lepidii, 15-25g of acanthopanax bark, 15-26g of rhizoma corydalis, 10-17g of radix angelicae, 18-25g of schisandra chinensis, 12-22g of hedysarum polybotrys, 16-25g of coptis chinensis and 15-25g of liquorice.

Preferably, the feed comprises the following raw materials by weight: 20-23g of dried ginger, 23-28g of black shun tablet, 15-18g of allium macrostemon, 18-23g of inula flower, 15-20g of cassia twig, 19-24g of storax, 23-27g of halloysite, 10-21g of ginkgo leaf, 15-25g of dark plum, 10-22g of zanthoxylum piperitum, 15-20g of salvia miltiorrhiza, 15-26g of ligusticum wallichii, 10-21g of semen lepidii, 15-25g of acanthopanax bark, 15-26g of rhizoma corydalis, 10-17g of radix angelicae, 18-25g of schisandra chinensis, 12-22g of hedysarum polybotrys, 16-25g of coptis chinensis and 15-20g of liquorice.

Preferably, the feed comprises the following raw materials by weight: 20-23g of dried ginger, 23-25g of black shun tablet, 15-17g of allium macrostemon, 18-20g of inula flower, 16-20g of cassia twig, 21-24g of storax, 23-26g of halloysite, 10-16g of ginkgo leaf, 15-20g of dark plum, 15-22g of zanthoxylum piperitum, 15-18g of salvia miltiorrhiza, 15-23g of ligusticum wallichii, 10-17g of semen lepidii, 15-19g of acanthopanax bark, 15-20g of rhizoma corydalis, 10-16g of radix angelicae, 18-22g of schisandra chinensis, 12-17g of hedysarum polybotrys, 16-20g of coptis chinensis and 15-18g of liquorice.

Preferably, the feed comprises the following raw materials by weight: 22g of dried ginger, 24g of black shun tablet, 16g of allium macrostemon, 19g of inula flower, 19g of cassia twig, 22g of storax, 24g of red halloysite, 16g of ginkgo leaf, 19g of dark plum, 22g of Sichuan green pepper, 16g of red sage root, 16g of ligusticum wallichii, 16g of semen lepidii, 18g of cortex acanthopanacis, 16g of rhizoma corydalis, 15g of radix angelicae, 19g of schisandra chinensis, 16g of hedysarum polybotrys, 18g of coptis chinensis and 17g of liquorice.

The working principle and the beneficial effects of the invention are as follows:

1. the traditional Chinese medicine preparation reasonably compatible with monarch, minister, assistant and guide has the effects of centering pathogenesis and treating bradycardia, one course of treatment lasts for 30 days, and the traditional Chinese medicine preparation has the effect after being taken for 10 days; the traditional Chinese medicine preparation is cured in 3-4 treatment courses, patients with the heart rate of 30-50 times/minute can reach 50-70 times/minute, the cure rate is more than 95%, and the recurrence rate is extremely low, so that the traditional Chinese medicine preparation for treating bradycardia disclosed by the invention is quick in effect, remarkable in curative effect and free of side effect, and the problem that the traditional Chinese medicine preparation for treating bradycardia in the prior art is not ideal in effect is solved.

2. The Chinese medicinal preparation takes the longstamen onion bulb, the salvia miltiorrhiza and the ligusticum wallichii as monarch medicaments, and has the effects of activating yang, resolving masses, promoting qi circulation, removing stagnation and protecting cardiac muscle; inula flower, storax, semen Lepidii and fructus Schisandrae chinensis are used as ministerial drugs to assist monarch drugs in treating myocardial weakness and promoting circulation of water, wherein Inula flower reduces qi and promotes circulation of water, storax dispels malaria in chest, semen Lepidii promotes water in chest; the dried ginger, the black shun tablet, the corydalis tuber, the angelica dahurica, the dark plum and the red halloysite are used as adjuvant medicines, wherein the dried ginger and the monkshood are pungent and capable of dispelling cold evil and supplementing kidney yang; corydalis tuber and dahurian angelica root are used for invigorating stomach and spleen and promoting absorption, and dark plum fruit and red halloysite are used for regulating and smoothing heart muscle and promoting valve healing; the liquorice is used as a medicine for harmonizing the effects of the other drugs in the recipe. The medicines are matched with each other to tonify heart yang and assist kidney yang, so that the body is full of yang qi, the heart is strengthened, the contractility of the two and three valves is doubled, and the pain of replacing or repairing the valves in an operation is avoided.

3. The traditional Chinese medicine preparation is an integral composition which can not be split, each medicine plays a vital role in the composition, each medicine supplements each other, not only plays respective efficacy, but also promotes the exertion of other drug effects and the inhibition of side effects, which is a result of long-term summary, the respective dosage of the traditional Chinese medicine preparation determines the drug effect of the whole preparation, and when the traditional Chinese medicine preparation is used in a prescription, on the basis of the understanding of the pathogenesis of bradycardia by the traditional Chinese medicine, the traditional Chinese medicine preparation not only carefully selects and protects the myocardial drugs, but also combines the deficiency of lung qi, the stagnation of liver qi and the stagnation of liver qi, and the characteristic of the main treatment section that the traditional Chinese medicine preparation cannot help the heart, thereby enriching the principles of tonifying qi and blood, regulating qi and dredging collaterals. The traditional Chinese medicine theory and the modern science are combined to treat bradycardia, and the traditional Chinese medicine theory and the modern science are innovated by tonifying qi and blood, regulating qi and dredging collaterals, and are obtained by long-term research and summary of an inventor. The usage amount of radix hedysari in the composition is determined according to the basic pathogenesis of bradycardia, long-term mental malnutrition, qi depression transforming into fire, aggravation of qi consumption and deficiency of qi, wherein the radix hedysari can tonify qi, has poor effect when in small amount and is more deficient and not supplemented. Corydalis tuber has the effects of soothing liver and promoting qi circulation, and is slow in effect when being used in a small amount, and can stimulate gastrointestinal tracts when being used in a large amount, so that nausea, vomiting and stomach distending pain can be caused, appetite can be reduced, and diet is not thought, so that slow tonifying is suitable for basic patients with bradycardia but severe tonifying is not suitable for basic patients.

Dried ginger: is dried rhizome of Zingiber officinale Roscoe of Zingiberaceae. Nature and taste: pungent and hot. It enters spleen, stomach, kidney, heart and lung meridians. The efficacy is as follows: gan Jiang warms the middle-jiao to dispel cold, returns yang to activate collaterals, eliminates dampness and eliminates phlegm. Can be used for treating abdominal psychroalgia, emesis, diarrhea, cold limbs, slight pulse, phlegm retention, asthma, and cough. The compendium records: gan Jiang can induce blood to enter blood system and qi to enter qi system. It can also remove the aversion to nourishing yin and nourish new, so it is good at growing yin and yang.

Black plain film: pungent, sweet and big heat; is toxic. It enters heart, kidney and spleen meridians. The efficacy is as follows: reviving yang to rescue adverse qi, tonifying fire to strengthen yang, and expelling pathogenic wind, cold and dampness.

And (3) inula flower: bitter, pungent and salty in flavor, slightly warm in nature; it enters lung and stomach meridians. The efficacy is as follows: dispel phlegm and promote diuresis, direct qi downward and stop vomiting.

And (3) allium macrostemon: is dried bulb of Allium tenuipilum of Liliaceae. Nature and taste: pungent, bitter and warm. It enters lung, stomach and large intestine meridians. The efficacy is as follows: activate yang and dissipate nodulation, move qi and remove stagnation. Can be used for treating thoracic obstruction and pain, cough and asthma due to phlegm-fluid retention, and diarrhea and tenesmus. The records in the book "materia medica shiyi" (herbal medicine for the deceased) are: in middle energizer, patients with persistent preference and no cure, but with aversion to heat in the abdomen, they should be decocted.

Cassia twig: is dried twig of Cinnamomum cassia Presl of Lauraceae. Collected in spring and summer, leaves are removed, and the tea is dried in the sun or sliced and dried in the sun. Nature and taste: pungent, sweet and warm. It enters heart, lung and bladder meridians. It is mainly used for treating sweating and relieving muscles, warming and activating meridians, supporting yang and regulating qi, and calming the adverse-rising energy. Can be used for treating wind-cold type common cold, abdominal psychroalgia, blood cold amenorrhea, arthralgia, phlegm retention, edema, palpitation, and galloping.

Storax: pungent and warm. Meridian tropism enters heart and spleen meridians. The efficacy is as follows: stealing, removing filth and relieving pain.

Halloysitum rubrum: sweet, sour, astringent and warm in nature and taste. The meridian tropism enters stomach and large intestine meridians. The efficacy is as follows: astringing intestines; astringing to stop bleeding; astringing dampness and healing wound; promote tissue regeneration.

Dark plum: sour, astringent and flat; it enters liver, spleen, lung and large intestine meridians. The efficacy is as follows: astringe lung, astringe intestine, promote fluid production and relieve ascaris.

Red sage root: is dried root and rhizome of Salvia miltiorrhiza Bunge of Labiatae. Nature and taste: bitter and slightly cold. It enters heart and liver meridians. The efficacy is as follows: dispel stasis and alleviate pain, activate blood and dredge meridians, clear heart fire and relieve restlessness. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal mass, thoracico-abdominal pain, arthralgia due to heat, pyocutaneous disease, swelling and pain, vexation, and insomnia; hepatosplenomegaly, angina pectoris. The Yunnan herbal medicine records: tonify heart and calm mind, induce tranquilization and calm heart. It is indicated for amnesia, palpitation, insomnia, and fright.

Ligusticum wallichii: is dried rhizome of Umbelliferae plant rhizoma Ligustici Chuanxiong. Nature and taste: pungent and warm. It enters liver, gallbladder and pericardium meridians. The efficacy is as follows: promote blood circulation and move qi, dispel wind and alleviate pain. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia. The Chinese herbal medicine is recorded in Rihuazi Bencao: for treating wind, qi, strain, blood, internal fatigue, strengthening tendons and bones, regulating the channels, breaking mass and blood stasis, nourishing new blood, growing flesh, rhinorrhea, hematemesis and drowning, hemorrhoids and fistula, cerebral carbuncle and back, scrofula and gall, sore and scabies, pus discharge and blood stasis.

Sichuan green pepper: hot, pungent; heart and spleen meridians entered; warming middle energizer to dispel cold, stimulating appetite and promoting digestion.

Ginkgo leaf: sweet, bitter, astringent and mild; heart and lung meridian entered; the efficacy is as follows: astringe lung, relieve asthma, activate blood and resolve stasis, alleviate pain.

Semen lepidii: bitter, pungent and cold; it enters lung and bladder meridians. The efficacy is as follows: purge lung, relieve dyspnea, induce diuresis to alleviate edema.

Rhizoma corydalis: pungent, bitter and warm; it enters heart, liver and spleen meridians. The efficacy is as follows: activate blood, move qi and alleviate pain.

Radix angelicae: pungent and warm; it enters lung, stomach and large intestine meridians. The efficacy is as follows: relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, relieving leukorrhagia, relieving swelling, expelling pus, dispelling pathogenic wind, and relieving itching.

Cortex acanthopanacis: it enters liver and kidney meridians. The efficacy is as follows: dispelling pathogenic wind, removing dampness, promoting blood circulation, and removing blood stasis.

Schisandra chinensis: is dried mature fruit of Schisandra chinensis or Schisandra sphenanthera of Magnoliaceae. Nature and taste: sour, sweet and warm. It enters lung, heart and kidney meridians. The efficacy is as follows: astringe to arrest discharge, benefit qi and promote the production of body fluid, tonify kidney and calm heart. Can be used for treating chronic cough, asthma, nocturnal emission, enuresis, frequent micturition, chronic diarrhea, spontaneous perspiration, night sweat, thirst due to body fluid consumption, short breath, weak pulse, internal heat, diabetes, palpitation, and insomnia.

Radix hedysari: warm in nature and sweet in taste; it enters lung and spleen meridians. The efficacy is as follows: consolidating superficial resistance to arrest sweating, invigorating qi, inducing diuresis, expelling toxin and healing wound.

Coptis chinensis: bitter and cold; it enters heart, spleen, stomach, gallbladder and large intestine meridians. The efficacy is as follows: clear heat and dry dampness, purge fire and remove toxicity.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 10g of dried ginger, 10g of black shun tablet, 10g of allium macrostemon, 10g of inula flower, 10g of cassia twig, 10g of storax, 10g of red halloysite, 10g of ginkgo leaf, 10g of dark plum, 10g of Sichuan green pepper, 10g of red sage root, 10g of ligusticum wallichii, 10g of semen lepidii, 10g of cortex acanthopanacis, 10g of rhizoma corydalis, 10g of radix angelicae, 10g of schisandra chinensis, 10g of radix hedysari, 10g of coptis chinensis and 10g of liquorice.

Example 2

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 30g of dried ginger, 20g of black shun tablet, 30g of allium macrostemon, 20g of inula flower, 30g of cassia twig, 30g of storax, 20g of red halloysite, 30g of ginkgo leaf, 20g of dark plum, 20g of Sichuan green pepper, 30g of red sage root, 30g of ligusticum wallichii, 20g of semen lepidii, 20g of cortex acanthopanacis, 30g of rhizoma corydalis, 20g of radix angelicae, 30g of schisandra chinensis, 20g of hedysarum polybotrys, 20g of coptis chinensis and 30g of liquorice.

Example 3

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 20g of dried ginger, 30g of black shun tablet, 20g of allium macrostemon, 30g of inula flower, 25g of cassia twig, 15g of storax, 30g of red halloysite, 10g of ginkgo leaf, 30g of dark plum, 25g of Sichuan green pepper, 15g of red sage root, 15g of ligusticum wallichii, 25g of semen lepidii, 30g of cortex acanthopanacis, 15g of rhizoma corydalis, 10g of radix angelicae, 18g of schisandra chinensis, 30g of radix hedysari, 30g of coptis chinensis and 25g of liquorice.

Example 4

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 25g of dried ginger, 25g of black shun tablet, 15g of allium macrostemon, 15g of inula flower, 10g of cassia twig, 20g of storax, 20g of red halloysite, 15g of ginkgo leaf, 15g of dark plum, 10g of Sichuan green pepper, 20g of red sage root, 20g of ligusticum wallichii, 10g of semen lepidii, 15g of cortex acanthopanacis, 20g of rhizoma corydalis, 20g of radix angelicae, 20g of schisandra chinensis, 12g of hedysarum polybotrys, 16g of coptis chinensis and 10g of liquorice.

Example 5

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 20g of dried ginger, 28g of black shun tablet, 10g of allium macrostemon, 23g of inula flower, 20g of cassia twig, 15g of storax, 27g of red halloysite, 21g of ginkgo leaf, 25g of dark plum, 22g of Sichuan green pepper, 15g of red sage root, 15g of ligusticum wallichii, 21g of semen lepidii, 25g of cortex acanthopanacis, 26g of rhizoma corydalis, 10g of radix angelicae, 25g of schisandra chinensis, 22g of hedysarum polybotrys, 25g of coptis chinensis and 25g of liquorice.

Example 6

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 23g of dried ginger, 20g of black shun tablet, 18g of allium macrostemon, 15g of inula flower, 10g of cassia twig, 24g of storax, 20g of red halloysite, 10g of ginkgo leaf, 15g of dark plum, 10g of Sichuan green pepper, 20g of red sage root, 26g of ligusticum wallichii, 10g of semen lepidii, 15g of cortex acanthopanacis, 15g of rhizoma corydalis, 17g of radix angelicae, 18g of schisandra chinensis, 12g of radix hedysari, 16g of coptis chinensis and 15g of liquorice.

Example 7

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 22g of dried ginger, 24g of black shun tablet, 16g of allium macrostemon, 19g of inula flower, 19g of cassia twig, 22g of storax, 24g of red halloysite, 16g of ginkgo leaf, 19g of dark plum, 22g of Sichuan green pepper, 16g of red sage root, 16g of ligusticum wallichii, 16g of semen lepidii, 18g of cortex acanthopanacis, 16g of rhizoma corydalis, 15g of radix angelicae, 19g of schisandra chinensis, 16g of hedysarum polybotrys, 18g of coptis chinensis and 17g of liquorice.

Example 8

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 20g of dried ginger, 28g of black shun tablet, 15g of allium macrostemon, 23g of inula flower, 15g of cassia twig, 24g of storax, 23g of red halloysite, 21g of ginkgo leaf, 15g of dark plum, 22g of Sichuan green pepper, 15g of red sage root, 26g of ligusticum wallichii, 10g of semen lepidii, 25g of cortex acanthopanacis, 15g of rhizoma corydalis, 17g of radix angelicae, 18g of schisandra chinensis, 22g of hedysari, 16g of coptis chinensis and 20g of liquorice.

Example 9

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 23g of dried ginger, 23g of black shun tablet, 17g of allium macrostemon, 18g of inula flower, 20g of cassia twig, 21g of storax, 26g of red halloysite, 10g of ginkgo leaf, 20g of dark plum, 15g of Sichuan green pepper, 18g of red sage root, 15g of ligusticum wallichii, 17g of semen lepidii, 15g of cortex acanthopanacis, 20g of rhizoma corydalis, 10g of radix angelicae, 22g of schisandra chinensis, 12g of radix hedysari, 20g of coptis chinensis and 15g of liquorice.

Example 10

A traditional Chinese medicine preparation for treating bradycardia comprises the following raw materials by weight: 20g of dried ginger, 25g of black shun tablet, 15g of allium macrostemon, 20g of inula flower, 16g of cassia twig, 24g of storax, 23g of red halloysite, 16g of ginkgo leaf, 15g of dark plum, 22g of Sichuan green pepper, 15g of red sage root, 23g of ligusticum wallichii, 10g of semen lepidii, 19g of cortex acanthopanacis, 15g of rhizoma corydalis, 16g of radix angelicae, 18g of schisandra chinensis, 17g of hedysarum polybotrys, 16g of coptis chinensis and 18g of liquorice.

The traditional Chinese medicine preparation for treating bradycardia in the embodiments 1-10 can be directly powdered and taken with water; the composition is taken with water 10-30g in the morning, at noon and evening, and is taken warmly within one hour after meal.

Clinical trial

1. The traditional Chinese medicine preparation for treating bradycardia is obtained by continuous improvement of a large number of long-term researches of an inventor, 220 patients are confirmed to be treated and diagnosed, and the patients are randomly divided into a treatment group and a control group, wherein 110 patients are in the treatment group, 55 patients are in males and 55 patients are in females, the age is 30-65 years, the course is different from several months to several years, and the average course is 2 years; the control group comprises 110 cases, wherein 55 cases of men and 55 cases of women are aged 30-65 years, the course of disease is different from months to years, and the average course of disease is 2 years. The basic data of age, sex, course of disease, etc. of two groups of patients are basically the same, and the difference has no statistical significance (P is more than 0.05).

2. Diagnostic criteria

Heart rate below 60 beats/minute; the clinical manifestations are as follows: palpitation, shortness of breath, lassitude, weakness, dizziness, and even syncope; the tongue is pale with white coating, and the pulse is deep and slow or deep and weak; the electrocardiogram makes sure that the heart is bradycardia.

2. The treatment method comprises the following steps:

the Chinese medicinal preparation of the embodiment 7 of the invention is taken by a treatment group, and 20g of the Chinese medicinal preparation is taken after 20g of the Chinese medicinal preparation is pulverized and taken with water 3 times a day in the morning, at half an hour after meals; 30 days are 1 course of treatment, 1-3 courses of treatment are carried out, and the dosage of patients with serious illness is increased according to the advice of doctors.

The control group adopts conventional western medicine isoproterenol treatment method, the treatment observation period is 30 days, and 0.5-1mg of isoproterenol is slowly dripped into 200-300 ml of 5% glucose solution.

3. The therapeutic effect judgment standard is as follows: the standard of curative effect refers to the standard of judgment of curative effect of Chinese medicine diseases.

And (3) curing: the clinical symptoms of the patient basically disappear, and the electrocardiogram of the patient returns to normal, and reaches or exceeds 60 times/minute.

The effect is shown: the clinical symptoms of the patient are obviously relieved and improved, and the electrocardiogram is improved.

The method has the following advantages: the clinical symptoms of the patient are relieved and improved, and the electrocardiogram is improved.

And (4) invalidation: the clinical symptoms are not as adverse or aggravated.

4. And (3) comprehensive curative effect statistics: 105 patients are cured, 1 patient has obvious effect, 1 patient has effect and 3 patients have no effect, the total effective rate reaches 97.3 percent, and 3 patients who are cured in three treatment courses have 3 relapses after one year follow-up visit, and the results are shown in the following table 1.

TABLE 1 comprehensive therapeutic effects

As can be seen from the above table 1, the cure rate of the traditional Chinese medicine for treating bradycardia is 53.6 percent in one course of treatment, 82.7 percent in two courses of treatment and 95.5 percent in three courses of treatment. The traditional Chinese medicine has a remarkable effect of treating bradycardia, is low in price, does not have adverse reaction and any toxic or side effect, and is good news of patients with bradycardia. By comparing the total treatment effective rates of patients in a treatment group and patients in a control group, the treatment group is obviously higher than the control group, so that the traditional Chinese medicine has a good clinical effect on treating bradycardia, can effectively improve the cure rate of treatment, has an obvious effect, and solves the problem that the traditional Chinese medicine for treating bradycardia in the prior art has a non-ideal effect.

Typical cases and efficacy:

case 1. Wangzhi, male, age 56. Brief history of disease: myocarditis was developed one year ago, and after the treatment, symptoms of chest distress, palpitation and short breath were obvious, and the symptoms became worse after slight activities. The patient is diagnosed in 2018 in 9 months, the heart rate is slow for about 40 times per minute, bradycardia is confirmed, the traditional Chinese medicine preparation disclosed in embodiment 4 of the invention is orally taken for treatment, the traditional Chinese medicine preparation is powdered and taken 3 times in the morning, at noon and at night every day, 20g of the traditional Chinese medicine preparation is taken every time, the traditional Chinese medicine preparation is taken half an hour after meals, the symptoms of chest distress, palpitation and shortness of breath are obviously relieved after 10 days, the patient can be healed after one treatment course, the heart rate is recovered for about 62 times per minute, and the patient.

Case 2. lithangiur, male, 62 years old. Brief history of disease: chest distress, palpitation and shortness of breath have been evident in recent years. The traditional Chinese medicine preparation disclosed by the embodiment 7 of the invention is taken after being powdered and infused 3 times in the morning, noon and evening every day, 30g of the powder is taken every time, and the traditional Chinese medicine preparation is taken half an hour after meals, after one treatment course, the symptoms of chest distress and palpitation and short breath are obviously improved, the symptoms of the chest distress and palpitation are completely cured after three treatment courses, the heart rate is 70 times per minute, the symptoms of the chest distress and palpitation and the short breath completely disappear, and the follow-up visit is not repeated so far.

Case 3. Zhouji, female, 38 years old. Brief history of disease: chest distress, palpitation, shortness of breath and 30 heart rates per minute were evident in the last year, but many treatments had no effect. The patient is diagnosed in 2017 in 4 months, the traditional Chinese medicine preparation disclosed by the embodiment 2 of the invention is taken 10g each time after 3 times of each day in the morning, at noon and at night after meals, after one treatment course, the symptoms of chest distress, palpitation and short breath are obviously improved, after two treatment courses, the heart rate is 63 times/minute, the symptoms of chest distress, palpitation and short breath completely disappear, and the disease does not relapse after follow-up for one year.

The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions, improvements, etc. within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A traditional Chinese medicine preparation for treating bradycardia is characterized by comprising the following raw materials by weight: 10-30g of dried ginger, 10-30g of black shun tablet, 10-30g of allium macrostemon, 10-30g of inula flower, 10-30g of cassia twig, 10-30g of storax, 10-30g of halloysite, 10-30g of ginkgo leaf, 10-30g of dark plum, 10-30g of zanthoxylum piperitum, 10-30g of salvia miltiorrhiza, 10-30g of ligusticum wallichii, 10-30g of semen lepidii, 10-30g of cortex acanthopanacis, 10-30g of rhizoma corydalis, 10-30g of radix angelicae, 10-30g of schisandra chinensis, 10-30g of hedysarum polybotrys, 10-30g of coptis chinensis and 10-30g of liquorice.

2. The traditional Chinese medicine preparation for treating bradycardia according to claim 1, which is characterized by comprising the following raw materials by weight: 20-30g of dried ginger, 20-30g of black shun tablet, 10-20g of allium macrostemon, 15-30g of inula flower, 10-25g of cassia twig, 15-30g of storax, 20-30g of halloysite, 10-25g of ginkgo leaf, 15-30g of dark plum, 10-25g of zanthoxylum piperitum, 15-30g of salvia miltiorrhiza, 15-30g of ligusticum wallichii, 10-25g of semen lepidii, 15-30g of acanthopanax bark, 15-30g of rhizoma corydalis, 10-20g of radix angelicae, 18-30g of schisandra chinensis, 12-30g of hedysarum polybotrys, 16-30g of coptis chinensis and 10-25g of liquorice.

3. The traditional Chinese medicine preparation for treating bradycardia according to claim 1, which is characterized by comprising the following raw materials by weight: 20-25g of dried ginger, 20-28g of black shun tablet, 10-18g of allium macrostemon, 15-23g of inula flower, 10-20g of cassia twig, 15-24g of storax, 20-27g of halloysite, 10-21g of ginkgo leaf, 15-25g of dark plum, 10-22g of zanthoxylum piperitum, 15-20g of salvia miltiorrhiza, 15-26g of ligusticum wallichii, 10-21g of semen lepidii, 15-25g of acanthopanax bark, 15-26g of rhizoma corydalis, 10-17g of radix angelicae, 18-25g of schisandra chinensis, 12-22g of hedysarum polybotrys, 16-25g of coptis chinensis and 15-25g of liquorice.

4. The traditional Chinese medicine preparation for treating bradycardia according to claim 1, which is characterized by comprising the following raw materials by weight: 20-23g of dried ginger, 23-28g of black shun tablet, 15-18g of allium macrostemon, 18-23g of inula flower, 15-20g of cassia twig, 19-24g of storax, 23-27g of halloysite, 10-21g of ginkgo leaf, 15-25g of dark plum, 10-22g of zanthoxylum piperitum, 15-20g of salvia miltiorrhiza, 15-26g of ligusticum wallichii, 10-21g of semen lepidii, 15-25g of acanthopanax bark, 15-26g of rhizoma corydalis, 10-17g of radix angelicae, 18-25g of schisandra chinensis, 12-22g of hedysarum polybotrys, 16-25g of coptis chinensis and 15-20g of liquorice.

5. The traditional Chinese medicine preparation for treating bradycardia according to claim 1, which is characterized by comprising the following raw materials by weight: 20-23g of dried ginger, 23-25g of black shun tablet, 15-17g of allium macrostemon, 18-20g of inula flower, 16-20g of cassia twig, 21-24g of storax, 23-26g of halloysite, 10-16g of ginkgo leaf, 15-20g of dark plum, 15-22g of zanthoxylum piperitum, 15-18g of salvia miltiorrhiza, 15-23g of ligusticum wallichii, 10-17g of semen lepidii, 15-19g of acanthopanax bark, 15-20g of rhizoma corydalis, 10-16g of radix angelicae, 18-22g of schisandra chinensis, 12-17g of hedysarum polybotrys, 16-20g of coptis chinensis and 15-18g of liquorice.

6. The traditional Chinese medicine preparation for treating bradycardia according to claim 1, which is characterized by comprising the following raw materials by weight: 22g of dried ginger, 24g of black shun tablet, 16g of allium macrostemon, 19g of inula flower, 19g of cassia twig, 22g of storax, 24g of red halloysite, 16g of ginkgo leaf, 19g of dark plum, 22g of Sichuan green pepper, 16g of red sage root, 16g of ligusticum wallichii, 16g of semen lepidii, 18g of cortex acanthopanacis, 16g of rhizoma corydalis, 15g of radix angelicae, 19g of schisandra chinensis, 16g of hedysarum polybotrys, 18g of coptis chinensis and 17g of liquorice.