CN111436520A - Chewing gum for whitening teeth - Google Patents
Chewing gum for whitening teeth Download PDFInfo
- Publication number
- CN111436520A CN111436520A CN201910041752.5A CN201910041752A CN111436520A CN 111436520 A CN111436520 A CN 111436520A CN 201910041752 A CN201910041752 A CN 201910041752A CN 111436520 A CN111436520 A CN 111436520A
- Authority
- CN
- China
- Prior art keywords
- chewing gum
- tooth whitening
- sodium
- agent
- chewing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002087 whitening effect Effects 0.000 title claims abstract description 79
- 235000015218 chewing gum Nutrition 0.000 title claims abstract description 54
- 229940112822 chewing gum Drugs 0.000 title claims abstract description 51
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 29
- 239000000126 substance Substances 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 12
- 239000000203 mixture Substances 0.000 claims abstract description 10
- 239000003381 stabilizer Substances 0.000 claims abstract description 9
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 12
- 235000003599 food sweetener Nutrition 0.000 claims description 8
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 claims description 8
- 239000003765 sweetening agent Substances 0.000 claims description 8
- 239000003975 dentin desensitizing agent Substances 0.000 claims description 6
- UZJGVXSQDRSSHU-UHFFFAOYSA-N 6-(1,3-dioxoisoindol-2-yl)hexaneperoxoic acid Chemical compound C1=CC=C2C(=O)N(CCCCCC(=O)OO)C(=O)C2=C1 UZJGVXSQDRSSHU-UHFFFAOYSA-N 0.000 claims description 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical class OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 4
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 claims description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 4
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 4
- FENRSEGZMITUEF-ATTCVCFYSA-E [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].OP(=O)([O-])O[C@@H]1[C@@H](OP(=O)([O-])[O-])[C@H](OP(=O)(O)[O-])[C@H](OP(=O)([O-])[O-])[C@H](OP(=O)(O)[O-])[C@H]1OP(=O)([O-])[O-] Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].OP(=O)([O-])O[C@@H]1[C@@H](OP(=O)([O-])[O-])[C@H](OP(=O)(O)[O-])[C@H](OP(=O)([O-])[O-])[C@H](OP(=O)(O)[O-])[C@H]1OP(=O)([O-])[O-] FENRSEGZMITUEF-ATTCVCFYSA-E 0.000 claims description 4
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 claims description 4
- IOUCSUBTZWXKTA-UHFFFAOYSA-N dipotassium;dioxido(oxo)tin Chemical compound [K+].[K+].[O-][Sn]([O-])=O IOUCSUBTZWXKTA-UHFFFAOYSA-N 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 claims description 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 4
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims description 4
- 235000010333 potassium nitrate Nutrition 0.000 claims description 4
- 239000004323 potassium nitrate Substances 0.000 claims description 4
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims description 4
- 229940083982 sodium phytate Drugs 0.000 claims description 4
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims description 4
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims description 4
- 239000000811 xylitol Substances 0.000 claims description 4
- 235000010447 xylitol Nutrition 0.000 claims description 4
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 4
- 229960002675 xylitol Drugs 0.000 claims description 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 3
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims description 3
- 229920000388 Polyphosphate Polymers 0.000 claims description 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 3
- 229920001577 copolymer Polymers 0.000 claims description 3
- 239000010642 eucalyptus oil Substances 0.000 claims description 3
- 229940044949 eucalyptus oil Drugs 0.000 claims description 3
- 239000001683 mentha spicata herb oil Substances 0.000 claims description 3
- 239000001205 polyphosphate Substances 0.000 claims description 3
- 235000011176 polyphosphates Nutrition 0.000 claims description 3
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 3
- 229940048086 sodium pyrophosphate Drugs 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 235000010356 sorbitol Nutrition 0.000 claims description 3
- 235000019721 spearmint oil Nutrition 0.000 claims description 3
- 159000000008 strontium salts Chemical class 0.000 claims description 3
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims description 3
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 claims description 3
- 239000011701 zinc Substances 0.000 claims description 3
- 229910052725 zinc Inorganic materials 0.000 claims description 3
- 235000006076 zinc citrate Nutrition 0.000 claims description 3
- 239000011746 zinc citrate Substances 0.000 claims description 3
- 229940068475 zinc citrate Drugs 0.000 claims description 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 2
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 claims description 2
- 239000004343 Calcium peroxide Substances 0.000 claims description 2
- 239000004155 Chlorine dioxide Substances 0.000 claims description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- 244000043261 Hevea brasiliensis Species 0.000 claims description 2
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Natural products CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 claims description 2
- 229930195725 Mannitol Natural products 0.000 claims description 2
- 229920002367 Polyisobutene Polymers 0.000 claims description 2
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 claims description 2
- 108010073771 Soybean Proteins Proteins 0.000 claims description 2
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 2
- YDONNITUKPKTIG-UHFFFAOYSA-N [Nitrilotris(methylene)]trisphosphonic acid Chemical compound OP(O)(=O)CN(CP(O)(O)=O)CP(O)(O)=O YDONNITUKPKTIG-UHFFFAOYSA-N 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 2
- MTAZNLWOLGHBHU-UHFFFAOYSA-N butadiene-styrene rubber Chemical compound C=CC=C.C=CC1=CC=CC=C1 MTAZNLWOLGHBHU-UHFFFAOYSA-N 0.000 claims description 2
- LHJQIRIGXXHNLA-UHFFFAOYSA-N calcium peroxide Chemical compound [Ca+2].[O-][O-] LHJQIRIGXXHNLA-UHFFFAOYSA-N 0.000 claims description 2
- 235000019402 calcium peroxide Nutrition 0.000 claims description 2
- 239000002738 chelating agent Substances 0.000 claims description 2
- 235000019398 chlorine dioxide Nutrition 0.000 claims description 2
- 229910001919 chlorite Inorganic materials 0.000 claims description 2
- 229910052619 chlorite group Inorganic materials 0.000 claims description 2
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 claims description 2
- 229940090960 diethylenetriamine pentamethylene phosphonic acid Drugs 0.000 claims description 2
- VTIIJXUACCWYHX-UHFFFAOYSA-L disodium;carboxylatooxy carbonate Chemical compound [Na+].[Na+].[O-]C(=O)OOC([O-])=O VTIIJXUACCWYHX-UHFFFAOYSA-L 0.000 claims description 2
- TVQLLNFANZSCGY-UHFFFAOYSA-N disodium;dioxido(oxo)tin Chemical compound [Na+].[Na+].[O-][Sn]([O-])=O TVQLLNFANZSCGY-UHFFFAOYSA-N 0.000 claims description 2
- DUYCTCQXNHFCSJ-UHFFFAOYSA-N dtpmp Chemical compound OP(=O)(O)CN(CP(O)(O)=O)CCN(CP(O)(=O)O)CCN(CP(O)(O)=O)CP(O)(O)=O DUYCTCQXNHFCSJ-UHFFFAOYSA-N 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 239000000594 mannitol Substances 0.000 claims description 2
- 235000010355 mannitol Nutrition 0.000 claims description 2
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 2
- 229940041616 menthol Drugs 0.000 claims description 2
- 229960001047 methyl salicylate Drugs 0.000 claims description 2
- 229920003052 natural elastomer Polymers 0.000 claims description 2
- 229920001194 natural rubber Polymers 0.000 claims description 2
- 235000019477 peppermint oil Nutrition 0.000 claims description 2
- 229910000073 phosphorus hydride Inorganic materials 0.000 claims description 2
- 229920002689 polyvinyl acetate Polymers 0.000 claims description 2
- 239000011118 polyvinyl acetate Substances 0.000 claims description 2
- 239000011347 resin Substances 0.000 claims description 2
- 229920005989 resin Polymers 0.000 claims description 2
- 239000001509 sodium citrate Substances 0.000 claims description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- 229960001790 sodium citrate Drugs 0.000 claims description 2
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- 229940045872 sodium percarbonate Drugs 0.000 claims description 2
- 229940079864 sodium stannate Drugs 0.000 claims description 2
- YKLJGMBLPUQQOI-UHFFFAOYSA-M sodium;oxidooxy(oxo)borane Chemical compound [Na+].[O-]OB=O YKLJGMBLPUQQOI-UHFFFAOYSA-M 0.000 claims description 2
- 229940001941 soy protein Drugs 0.000 claims description 2
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- 125000005402 stannate group Chemical group 0.000 claims description 2
- 229940013618 stevioside Drugs 0.000 claims description 2
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 2
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- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 claims description 2
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 claims 2
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- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims 1
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- MPDGHEJMBKOTSU-UHFFFAOYSA-N Glycyrrhetinsaeure Natural products C12C(=O)C=C3C4CC(C)(C(O)=O)CCC4(C)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(C)C MPDGHEJMBKOTSU-UHFFFAOYSA-N 0.000 claims 1
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- 230000037336 dry skin Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000025 natural resin Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 150000004965 peroxy acids Chemical class 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 235000019448 polyvinylpyrrolidone-vinyl acetate copolymer Nutrition 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000036345 yellow teeth Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/08—Chewing gum characterised by the composition containing organic or inorganic compounds of the chewing gum base
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Cosmetics (AREA)
- Confectionery (AREA)
Abstract
The invention aims to provide a chewing gum which can remove tartar and whiten teeth only by chewing the chewing gum, and an elastic gum base with strong adhesiveness is taken as a carrier, wherein a specific adhesive substance is added to ensure that the chewing gum only has strong adhesive effect on the teeth in the chewing process, and the chewing gum is matched with a tooth whitening agent and other effective ingredients and dispersed in the gum base carrier to form a novel tooth whitening product; in addition, peroxide stabilizer compositions are disclosed which allow the whitening material to remain stable for a sufficient period of time and to be slowly released by chewing on the teeth and by saliva to whiten the teeth; in addition, the invention also relates to a whitening agent with tooth anti-allergy, safety and no stimulation, so that the tooth whitening process is safer, and the use experience is better.
Description
Technical Field
The invention relates to the field of food, in particular to chewing gum for whitening teeth.
Background
At present, the concept of oral care of most people in China still remains in the understanding of 'tooth brushing', and only a small part of people can select professional regular oral examination; in fact, the method of brushing teeth only can eliminate oral foreign matters, a small amount of dental plaque and tartar, but has no effect on the prevention and treatment of other problems such as tartar, yellow teeth, dental plaque and the like, and in order to have healthy and bright white teeth, whitening agent chemical treatment is often needed, two household type and professional type tooth whitening products are currently available on the market, a professional denture product is needed, then the whitening agent is uniformly coated on a denture, and the whitening agent is fully contacted with the teeth through occlusion of the teeth so as to react the tartar and pigments, so that the purpose of whitening the teeth is achieved (see detail in U.S. Pat. No. 5573399A and U.S. Pat. No. 6354837B 1). In addition, the tooth whitening strip for the household type is invented, the operation process is simple, the limitation of the use place is also solved, but the tooth whitening strip can only contact specific teeth and can not cover all the teeth, so that the tooth color is not uniform, and the gel backing layer of the tooth whitening strip can cause strong foreign body sensation, so that the tooth whitening strip is still not widely used and accepted. Therefore, the development of a product which can satisfy the tooth whitening requirement and is easy to accept becomes a problem to be solved urgently in the industry.
Disclosure of Invention
It should be understood that the detailed description and specific examples, while indicating embodiments of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
As used throughout this document, ranges are used as shorthand for describing each and every value that is within the range. Any value within the range can be selected as the terminus of the range.
The term "about", as used herein, when applied to values of parameters of the compositions and methods of the present invention, means that the calculation or measurement of the values allows some slight imprecision without having a substantial effect on the chemical or physical properties of the compositions or methods. If the imprecision provided by "about" for some reason is not otherwise understood in the art with this ordinary meaning, then "about" as used herein indicates a possible variation of up to 5% in the value.
As referred to herein, all compositional percentages are by weight of the total composition, unless otherwise specified.
The invention content is as follows:
the invention aims to provide a chewing gum which can remove tartar and whiten teeth only by chewing the chewing gum, and an elastic gum base with strong adhesiveness is taken as a carrier, wherein a specific adhesive substance is added to ensure that the chewing gum only has strong adhesive effect on the teeth in the chewing process, and the chewing gum is matched with a tooth whitening agent and other effective ingredients and dispersed in the gum base carrier to form a novel tooth whitening product; in addition, peroxide stabilizer compositions are disclosed which allow the whitening material to remain stable for a sufficient period of time and to be slowly released by chewing on the teeth and by saliva to whiten the teeth; in addition, the invention also relates to a whitening agent with tooth anti-allergy, safety and no stimulation, so that the tooth whitening process is safer, and the use experience is better.
In order to solve the above problems, the present invention provides a chewing gum for tooth whitening, comprising the following materials in parts by mass: chewing gum base material 70% -90%, tooth whitening agent 3% -12%, desensitizing agent 0.01% -5%, antiscaling agent 0.1% -5%, stabilizing agent 0% -0.5%, flavor and/or sweetener 0.1% -8%, potassium salt and/or strontium salt and/or fluoride of said desensitizing agent, said antiscaling agent polyphosphate and/or zinc containing composition, said stabilizing agent comprising chelating agent and/or EDTA salt and/or organic phosphoric acid and/or stannate.
According to embodiments of the invention, the chewing gum may typically weigh from 0.5g to 1.0 g. Weight herein refers to the neat content of the chewing gum, excluding the package. Of course, the weight of the chewing gum may be other preferred weights.
According to an experimental version of the invention, the chewing gum comprises between 70% and 90% by weight of chewing gum base material.
In an embodiment of the invention of this example, the chewing gum base material is a soluble gum base or an insoluble gum base, or a mixture thereof; wherein said soluble gum base is one or more selected from the group consisting of: edible gelatin, soy protein; wherein said insoluble gum base is a gum base comprising one or more substances selected from the group consisting of: polyisobutylene, isoprene copolymer, butadiene styrene rubber, polyvinyl acetate resin, natural rubber and natural rosin ester. The special adhesive substance is added into the base material, so that the chewing gum only has strong adhesion to teeth in the chewing process, and can effectively remove oral foreign matters and dental plaque; in addition, the chewing gum base is used as an inert carrier, provides effective attachment for other effective components, and is matched with a tooth whitening agent and other effective components, so that the effect of whitening teeth can be achieved.
According to the present invention, the chewing gum comprises 3% to 12% by weight of a tooth whitening agent, wherein the tooth whitening agent is one or more of a peroxide, a peroxyacid, and a chloride; more specifically, the tooth whitening agent comprises one or more substances selected from the group consisting of: hydrogen peroxide, urea peroxide, calcium peroxide, sodium percarbonate, sodium perborate, phthalimidoperoxycaproic acid, chlorite, hypochlorite, chlorine dioxide. The whitening agent slowly releases whitening factor during chewing and saliva soaking process of teeth, and the whitening factor can react with tooth pigment through dentinal tubule to whiten teeth.
For the tooth whitening chewing gum, in order to solve the problem of stability of the tooth whitening agent, according to the experimental scheme of the present invention, 0% to 0.5% of a specific whitening agent stabilizer is added, so that the tooth whitening chewing gum can realize good whitening stability. Preferably, the stabilizer comprises one or more substances selected from the group consisting of: EDTA, EDTA-2Na, phosphine polycarboxylic acid, aminotrimethylene phosphonic acid, diethylenetriamine pentamethylene phosphonic acid, sodium citrate, sodium phytate, potassium stannate and sodium stannate.
In addition, the embodiment also relates to a safe, effective and stable tooth whitening agent, namely phthalimido peroxy caproic acid, wherein the related tooth whitening agent, namely the phthalimido peroxy caproic acid, can effectively fade and remove tooth color, has whitening activity and does not cause allergy; no additional desensitizing agent is required.
According to the experimental scheme of the invention, the chewing gum comprises 0.01-5% by weight of desensitizer, wherein the desensitizer is potassium salt, strontium salt and fluoride, and is one or more substances consisting of the components; the addition of a proper amount of desensitizer can avoid the symptoms of tooth ache and sensitivity in the tooth whitening process.
According to an embodiment of the invention, the chewing gum includes 0.1-5% by weight of an anti-tartar agent, wherein the anti-tartar agent is a polyphosphate, a zinc-containing composition, or a combination thereof; the addition of an appropriate amount of an anticalculus agent can inhibit the formation of dental plaque and the deposition of tartar within a certain period of time.
According to an experimental embodiment of the invention, the chewing gum comprises 0.1% to 8% by weight of one or more substances selected from the group consisting of flavors and sweeteners.
The invention relates to a tooth whitening chewing gum, which has the following characteristics: the initial state is dry, where contact with dry skin such as hands, face, lips, etc. does not release whitening active factors, and when entering the moist oral cavity and contacting saliva, the hydrophilic glass polymer in the elastomeric base is hydrated while releasing whitening factors, thereby producing sufficient tooth whitening. The chewing gum base material is added with the hydrophilic glass polymer, when the chewing gum base material is hydrated, most of the hydrophilic glass polymer can provide enough bonding strength and keep a long-time contact state with teeth, so that most of released whitening factors act on the teeth, and the stimulation of the whitening agent to gum and oral cavity skin is reduced. Preferably, wherein the hydrophilic glass polymer is one or more selected from the group consisting of: polyalkyl vinyl ether-maleic acid copolymer, polyacrylic acid, polyvinylpyrrolidone-vinyl acetate copolymer.
The form and shape of the tooth whitening chewing gum according to the present invention may be any suitable and pleasant to use structure. Thus, the shape of the chewing gum may be selected from, for example, pills, sticks, tablets, blocks, lozenges, pellets, and spheres. Chewing gum may be shaped by extrusion, pressing, rolling and the center may be filled with any shape of liquid and/or solid.
The following examples are intended to illustrate but not limit the invention.
Example 1
Preparing a gum base:
component (wt%)
Natural resin 32
Synthetic resin 26
Elastic body 22
Hydrophilic glass polymer 20
It should be emphasized that several other gum base compositions within the scope of the present invention may also be employed.
Example 2
As described below, by using the gum base of example 1 and preparing a tooth whitening chewing gum according to a conventional mechanical mixing procedure,
component (wt%)
The gum base is 88.5 percent
3 percent of hydrogen peroxide
0.3 percent of potassium nitrate
0.2 percent of zinc citrate
0.15 percent of potassium stannate
Sodium phytate 0.05%
Xylitol 2%
Liquid sweetener 1.5%
Spearmint oil 0.2%
Eucalyptus oil 0.1%.
Example 3
Tooth whitening chewing gum was prepared by using the gum base of example 1 and following a conventional mechanical mixing procedure as described below.
Component (wt%)
The gum base is 88.25 percent
6 percent of hydrogen peroxide
0.5 percent of potassium nitrate
0.2 percent of sodium pyrophosphate
0.2 percent of potassium stannate
Sodium phytate 0.05%
Sorbitol powder 2.5%
Liquid sweetener 2%
Spearmint oil 0.2%
Eucalyptus oil 0.1%.
Example 4
Tooth whitening chewing gum was prepared by using the gum base of example 1 and following a conventional mechanical mixing procedure as described below.
Component (wt%)
The gum base is 79.8 percent
Carbamide peroxide 12%
0.5 percent of potassium nitrate
0.2 percent of sodium pyrophosphate
EDTA-2Na 0.05%
Stevioside 3%
0.2 percent of liquid sweetener
0.2 percent of methyl salicylate
0.05% of menthol.
Example 5
Tooth whitening chewing gum was prepared by using the gum base of example 1 and according to a conventional mechanical mixing procedure, with moderate use of heat, as follows:
component (wt%)
Gum base 84.05%
Peroxy caproic acid 8%
Zinc citrate 0.25
Xylitol 5%
Mannitol powder 2%
Liquid sweetener 0.5%
And 0.2% of peppermint oil.
Example 6.
The whitening effect of the tooth whitening chewing gums of examples 2 to 5 was evaluated according to the following protocol:
1) four bovine teeth with similar sizes on the same cow are taken, and the tooth surfaces are required to be smooth and have no cracks, defects and the like. Cleaning the surface of a toothbrush in advance, soaking, disinfecting and bleaching the surface for 48 hours by using low-concentration hydrogen peroxide at normal temperature, washing the surface by using clean water, and placing the surface in artificial saliva for later use;
2) soaking 20 g/L g of boiled and cooled Keemun black tea for 6h, repeatedly soaking twice to obtain teeth required by the experiment, carrying out tooth color comparison by using a Spectroshade color comparator, photographing and archiving, and placing the successfully dyed bovine teeth in artificial saliva for color fixation;
3) randomly selecting more than four treated bovine teeth, cleaning with clear water, respectively placing into 4 10ml centrifuge tubes, adding 0.5ml artificial saliva, and performing simulated chewing treatment of the tooth whitening chewing gum of the embodiment 2-5 in an incubator at 37 ℃;
4) the tooth color data was collected using a Spectroshade colorimeter at 5min, 10min, 15min, and 30min time points, the average value was repeated three times for each photographed colorimetry, and the collected color values were analyzed using the internationally recognized CIE (L, a, b) color evaluation system widely used in oral precision colorimetry.A system that allows any color to be evaluated in a three-dimensional space-L the value represents the brightness of the color, a the value represents the greenish red level of the color, and b the bluish yellow level of the color.
The following table 1 illustrates the change of tooth tone after the tooth whitening chewing gums of examples 2 to 5 are applied to the teeth.
Table 1: tooth color level change condition of tooth whitening chewing gum after acting on teeth
The CIE colorimetric data is calculated △ E, the statistical data are shown in figure 1, the chewing gums of examples 2-5 have certain tooth whitening effect and the whitening effect is correspondingly increased along with the increase of chewing time as can be seen from figure 1, the curves of example 2 and example 3 in figure 1 show that the tooth whitening effect is in direct proportion to the content of the hydrogen peroxide serving as a tooth whitening agent, the higher the content is, the better the whitening effect is, the curve of example 5 shows that the △ E value is up to 4 in 10min and up to 8 in 30min, and the whitening effect of 8% peroxy caproic acid is obvious.
FIG. 1 comparison of tooth whitening effects at different times
The CIE (L a, b) color evaluation system analyzed the change in each chromaticity contribution factor during the tooth color change, comparing the contribution of each chromaticity factor to the color change at the same time point (10min, 30min) in different examples, and the L ab system analysis showed that the contribution of each chromaticity factor to the tooth whitening effect was not averaged (table 2).
The weight of each chroma factor change value in the whole bleaching effect at 210 min and 30min in the table
The results of the evaluation of the whitening effect of the tooth whitening chewing gum according to example 6 show that it is currently effective to add a whitening ingredient to the chewing gum.
Claims (8)
1. A chewing gum for tooth whitening, comprising the following materials in mass fraction: chewing gum base material 70% -90%, tooth whitening agent 3% -12%, desensitizing agent 0.01% -5%, antiscaling agent 0.1% -5%, stabilizing agent 0% -0.5%, flavor and/or sweetener 0.1% -8%, potassium salt and/or strontium salt and/or fluoride of said desensitizing agent, said antiscaling agent polyphosphate and/or zinc containing composition, said stabilizing agent comprising chelating agent and/or EDTA salt and/or organic phosphoric acid and/or stannate.
2. The chewing gum for tooth whitening according to claim 1, wherein the chewing gum base material is a soluble gum base and/or an insoluble gum base, the soluble gum base being edible gelatin and/or soy protein, the insoluble gum base comprising one or more substances selected from the group consisting of: polyisobutylene, isoprene copolymer, butadiene styrene rubber, polyvinyl acetate resin, natural rubber and natural rosin ester.
3. The chewing gum for tooth whitening according to claim 1, wherein the tooth whitening agent comprises one or more substances selected from the group consisting of: hydrogen peroxide, urea peroxide, calcium peroxide, sodium percarbonate, sodium perborate, phthalimidoperoxycaproic acid, chlorite, hypochlorite, chlorine dioxide.
4. The chewing gum for tooth whitening according to claim 1, wherein the desensitizing agent comprises one or more substances selected from the group consisting of: potassium nitrate, potassium oxalate, strontium chloride, strontium acetate, stannous fluoride, sodium monofluorophosphate, sodium fluoride and calcium hydroxide.
5. The chewing gum for tooth whitening according to claim 1, wherein the anti-scaling agent comprises one or more substances selected from the group consisting of: sodium pyrophosphate, tetrasodium pyrophosphate, sodium acid pyrophosphate, sodium hexametaphosphate, sodium tripolyphosphate, sodium tetrapolyphosphate, tetrapotassium pyrophosphate, zinc citrate, etc.
6. The chewing gum for tooth whitening according to claim 1, wherein the stabilizer comprises one or more selected from the group consisting of: EDTA, EDTA-2Na, phosphine polycarboxylic acid, aminotrimethylene phosphonic acid, diethylenetriamine pentamethylene phosphonic acid, sodium citrate, sodium phytate, potassium stannate and sodium stannate.
7. The chewing gum for tooth whitening according to any of claims 1-6, wherein said flavor comprises one or more selected from the group consisting of: peppermint oil, menthol, spearmint oil, eucalyptus oil, fennel oil, methyl salicylate, and thymol.
8. The chewing gum for tooth whitening according to claim 7, wherein the sweetener comprises one or more substances selected from the group consisting of: sorbitol, maltitol, mannitol, xylitol, stevioside, sucralose, glycyrrhetinic acid, aspartame and acesulfame potassium.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023164863A1 (en) * | 2022-03-03 | 2023-09-07 | Mars Wrigley Confectionery (China) Limited | Deep cleaning chewing gum |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1320030A (en) * | 1998-09-25 | 2001-10-31 | 荷兰联合利华有限公司 | Oral composition with an improved teeth whitening effect |
| KR20030005155A (en) * | 2000-03-17 | 2003-01-17 | 주식회사 엘지생활건강 | Patches for teeth whitening |
| CN1878526A (en) * | 2003-12-08 | 2006-12-13 | 吉百利食品有限公司 | A solid oral tooth whithening composition |
| CN101663018A (en) * | 2006-12-07 | 2010-03-03 | 财团法人首尔大学校产学协力财团 | The transfer system of teeth whitening functional materials |
-
2019
- 2019-01-16 CN CN201910041752.5A patent/CN111436520A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1320030A (en) * | 1998-09-25 | 2001-10-31 | 荷兰联合利华有限公司 | Oral composition with an improved teeth whitening effect |
| KR20030005155A (en) * | 2000-03-17 | 2003-01-17 | 주식회사 엘지생활건강 | Patches for teeth whitening |
| CN1878526A (en) * | 2003-12-08 | 2006-12-13 | 吉百利食品有限公司 | A solid oral tooth whithening composition |
| CN101663018A (en) * | 2006-12-07 | 2010-03-03 | 财团法人首尔大学校产学协力财团 | The transfer system of teeth whitening functional materials |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023164863A1 (en) * | 2022-03-03 | 2023-09-07 | Mars Wrigley Confectionery (China) Limited | Deep cleaning chewing gum |
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Application publication date: 20200724 |