CN111420287A - Nuclear magnetic cell therapy device - Google Patents

Nuclear magnetic cell therapy device Download PDF

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Publication number
CN111420287A
CN111420287A CN202010287773.8A CN202010287773A CN111420287A CN 111420287 A CN111420287 A CN 111420287A CN 202010287773 A CN202010287773 A CN 202010287773A CN 111420287 A CN111420287 A CN 111420287A
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CN
China
Prior art keywords
cell therapy
nuclear magnetic
coil
magnetic cell
therapy device
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Withdrawn
Application number
CN202010287773.8A
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Chinese (zh)
Inventor
孙志强
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Guangdong Advanced Power Technology Co ltd
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Individual
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Priority to CN202010287773.8A priority Critical patent/CN111420287A/en
Priority to PCT/CN2020/094264 priority patent/WO2021208212A1/en
Publication of CN111420287A publication Critical patent/CN111420287A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Magnetic Treatment Devices (AREA)

Abstract

The invention discloses a nuclear magnetic cell therapy device, which comprises a sickbed body, wherein an adjustable therapy device for heating and destroying diseased cells of a patient is arranged on the outer side of the sickbed body, the nuclear magnetic cell therapy device can intensively heat and destroy cell proteins so as to quickly eliminate tumor cells, magnetic metal oxide (or other high-permeability materials) nano particles can be selectively injected into a tumor to avoid the death of healthy cells in the patient, the temperature of the nano particles is increased under the action of an alternating electromagnetic field of kilohertz and above, so that the tumor cells are eliminated, a large wound surface operation is effectively avoided, only minimally invasive injection is needed, and nano magnetic injection liquid is injected to a cancerous part.

Description

Nuclear magnetic cell therapy device
Technical Field
The invention relates to the technical field of medical instruments, in particular to a nuclear magnetic cell therapy device.
Background
At present, the existing clinical treatment of cancers mainly adopts a surgical excision combined radiochemical treatment mode, so that the trauma of a patient is large, the body damage is also large, and the recovery period is long. To this end, we propose a nuclear magnetic cell therapy device.
Disclosure of Invention
The present invention is directed to a nuclear magnetic cell therapy device to solve the problems set forth in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: nuclear-magnetism cell therapy device, including the sick bed body, the outside of sick bed body is equipped with the adjustable treatment device that heats destruction to patient's pathological change cell.
Preferably, the adjustable treatment device comprises an electrified coil arranged on the outer side of the sickbed body in a surrounding manner, a connecting piece capable of controlling the coil to generate an alternating magnetic field is arranged in the coil, a control device for stably controlling the voltage of the electrified coil is arranged on the electrified coil, a sampling protection device for checking the voltage is arranged at the output end of the electrified coil, and a cooling device is arranged on the outer side of the electrified coil;
the sickbed body is provided with a detection device for checking the temperature of an injection part of a patient for injecting the nano metal magnetic material.
Preferably, the connecting piece is a ferrite or copper or high-temperature superconductor.
Preferably, the control device comprises an alternating current power supply, an output end of the alternating current power supply is connected with a rectifier, an output end of the rectifier is connected with a filter, an output end of the filter is connected with an inverter, an output end of the inverter is electrically connected with an input end of the electrified coil, and the control device is arranged so as to realize the effect of stably controlling the voltage and the current in the circuit.
Preferably, the sample protection device includes the inverter circuit who is connected with circular telegram coil, the inverter circuit output is connected with DSP, the DSP output is connected with control circuit, and control circuit output and wave filter electric connection, through the sample protection device who is equipped with to can keep apart the effect of sampling, further improvement circular telegram coil's security performance to the circuit that lets in circular telegram coil.
Preferably, the DSP is provided with an overvoltage protection circuit and a filtering protection circuit, so that the circuit can be subjected to voltage stabilization protection.
Preferably, the detection device comprises a temperature detection sensor and an image detection sensor which are arranged on the sickbed, and the detection device can effectively detect the injection part of the patient.
Preferably, the cooling device is arranged around the outside of the energized coil, so that the effect of an excessive temperature of the energized coil can be exerted.
Compared with the prior art, the invention has the beneficial effects that:
the adjustable therapeutic device can intensively heat to destroy cell proteins, so that tumor cells are quickly eliminated, magnetic metal oxide (or other high-permeability materials) nano particles are selectively injected into a tumor to avoid the death of healthy cells in a patient body, and the temperature of the nano particles is increased under the action of an alternating electromagnetic field of kilohertz or above, so that the tumor cells are eliminated, the operation of a large wound surface is effectively avoided, and only minimally invasive injection is needed to inject the nano magnetic injection liquid into a cancerous position.
Drawings
FIG. 1 is a schematic diagram of the overall circuit connection of the present invention;
FIG. 2 is a schematic diagram of the circuit connection of the detecting device according to the present invention;
FIG. 3 is a schematic diagram of the overall implementation of the present invention.
In the figure: 1-a hospital bed body; 2-an adjustable treatment device; 3-electrifying the coil; 4-a control device; 5-a sampling protection device; 6-a cooling device; 7-a detection device; 8-alternating current power supply; 9-a rectifier; 10-a filter; 11-an inverter; 12-an inverter circuit; 13-DSP; 14-a control circuit; 15-overvoltage protection circuit; 16-a filter protection circuit; 17-a temperature detection sensor; 18-image detection sensor.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-3, the present invention provides a technical solution: nuclear magnetic cell therapy device, including sick bed body 1, the outside of sick bed body 1 is equipped with the adjustable treatment device 2 that heats destruction to patient's pathological change cell.
The adjustable treatment device 2 comprises an electrified coil 3 arranged on the outer side of the sickbed body 1 in a surrounding mode, the electrified coil 3 can be made of high-temperature superconducting materials, a connecting piece capable of controlling the coil to generate an alternating magnetic field is arranged inside the coil, a control device 4 for stably controlling the voltage of the electrified coil 3 is arranged on the electrified coil 3, a sampling protection device 5 for checking the voltage is arranged at the output end of the electrified coil 3, and a cooling device 6 is arranged on the outer side of the electrified coil 3;
the sickbed body 1 is provided with a detection device 7 for checking the temperature of an injection part of a patient, which is injected with a nano metal magnetic material, wherein the nano metal magnetic material can be non-toxic cobalt iron oxide.
The connecting piece is an iron oxide body or copper or a high-temperature superconductor.
The control device 4 comprises an alternating current power supply 8, the alternating current power supply 8 is 220V and 50Hz, the output end of the alternating current power supply 8 is connected with a rectifier 9, the output end of the rectifier 9 is connected with a filter 10, the output end of the filter 10 is connected with an inverter 11, and the output end of the inverter 11 is electrically connected with the input end of the electrified coil 3.
The sampling protection device 5 comprises an inverter circuit 12 connected with the electrified coil 3, the output end of the inverter circuit 12 is connected with a DSP13, the output end of the DSP13 is connected with a control circuit 14, and the output end of the control circuit 14 is electrically connected with the filter 10.
The DSP13 is provided with an overvoltage protection circuit 15 and a filter protection circuit 16.
The detection device 7 includes a temperature detection sensor 17 and an image detection sensor 18 provided on the bed.
The cooling device 6 is arranged around the outside of the energized coil 3.
The specific implementation mode is as follows: firstly, a patient lies on a sickbed body 1, then injection liquid containing nano metal magnetic materials is injected around the patient at a fixed point, the patient lies in a magnetic field to avoid other metal objects in the body, such as all metal objects of a heart support, a mobile phone, a necklace and the like, then an alternating current power supply 8 is started, the alternating current power supply 8 is rectified, filtered and then sent to an inverter 11 (or DC-AC conversion is carried out by adopting a direct current power supply), in a control circuit 14, in order to stabilize the voltage in the device within a desired value and prevent overvoltage, the output voltage and current need to be isolated and sampled, after conditioning, a conditioning signal is sent to a DSP13, and then the modified signal is obtained through the processing of an internal control algorithm to realize voltage stabilization, the output alternating current power supply 8 passes through a coil to excite ferrite (or copper or high-temperature superconductor and the like) in the coil, thereby sending out a controllable, the alternating frequency magnetic field is more than 1Khz, the heating of the high frequency alternating magnetic field to the nano metal magnetic material is realized, the heating is carried out to a certain temperature according to the characteristics of pathological change cells of a patient, and the thermal killing to the pathological change cells is realized, (moreover, the invention can be applied to medical treatment, biological seedling culture and the like, and the influence of an electromagnetic field on organisms is simulated, and corresponding short circuit protection, overvoltage protection, overcurrent protection and the like are set for the system in order to ensure the stability of a circuit).
The following is a specific experimental process to illustrate the usage of the nuclear magnetic cell therapy device provided by the present invention, and the implementation process is as follows:
1. two groups of mice with different cancers were used: mild aggressive colorectal cancer ST26 and aggressive breast cancer 4T 1.
2. The treatment effects of two malignant tumors at different temperatures are compared, and colorectal cancer cells are found to be more sensitive to high temperature and die at 41-43 ℃; the breast cancer cells have stronger resistance to high temperature, and can die at the temperature of more than 47 ℃; the survival rate of the mouse receiving the magnetic heat treatment at 46-48 ℃ or 58-60 ℃ is 25% -40%, and other cancer cells can obtain better data after being tested by referring to the data, so that the operation treatment is replaced, and the painless and atraumatic local cancer cell killing effect is realized.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. Nuclear magnetic cell therapy device, including sick bed body (1), its characterized in that: the outer side of the sickbed body (1) is provided with an adjustable treatment device (2) for heating and destroying diseased cells of a patient.
2. The nuclear magnetic cell therapy device according to claim 1, characterized in that: the adjustable treatment device (2) comprises an electrified coil (3) which is arranged on the outer side of the sickbed body (1) in a surrounding mode, a connecting piece capable of controlling the coil to generate an alternating magnetic field is arranged in the coil, a control device (4) for controlling the voltage stability of the electrified coil (3) is arranged on the electrified coil (3), a sampling protection device (5) for checking the voltage is arranged at the output end of the electrified coil (3), and a cooling device (6) is arranged on the outer side of the electrified coil (3);
the sickbed body (1) is provided with a detection device (7) for checking the temperature of an injection part of a patient for injecting the nano metal magnetic material.
3. The nuclear magnetic cell therapy device according to claim 2, characterized in that: the connecting piece is an iron oxide body or copper or a high-temperature superconductor.
4. The nuclear magnetic cell therapy device according to claim 2, characterized in that: controlling means (4) are including alternating current power supply (8), alternating current power supply (8) output is connected with rectifier (9), rectifier (9) output is connected with wave filter (10), wave filter (10) output is connected with dc-to-ac converter (11), and dc-to-ac converter (11) output and electrical coil (3) input electric connection.
5. The nuclear magnetic cell therapy device according to claim 2, characterized in that: sample protection device (5) include inverter circuit (12) be connected with circular telegram coil (3), inverter circuit (12) output is connected with DSP (13), DSP (13) output is connected with control circuit (14), and control circuit (14) output and wave filter (10) electric connection.
6. The device for nuclear magnetic cell therapy according to claim 5, characterized in that: and the DSP (13) is provided with an overvoltage protection circuit (15) and a filtering protection circuit (16).
7. The nuclear magnetic cell therapy device according to claim 2, characterized in that: the detection device (7) comprises a temperature detection sensor (17) and an image detection sensor (18) which are arranged on the sickbed.
8. The nuclear magnetic cell therapy device according to claim 2, characterized in that: the cooling device (6) is arranged outside the electrified coil (3) in a surrounding mode.
CN202010287773.8A 2020-04-13 2020-04-13 Nuclear magnetic cell therapy device Withdrawn CN111420287A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202010287773.8A CN111420287A (en) 2020-04-13 2020-04-13 Nuclear magnetic cell therapy device
PCT/CN2020/094264 WO2021208212A1 (en) 2020-04-13 2020-06-04 Nuclear magnetic cell therapy device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010287773.8A CN111420287A (en) 2020-04-13 2020-04-13 Nuclear magnetic cell therapy device

Publications (1)

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CN111420287A true CN111420287A (en) 2020-07-17

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WO (1) WO2021208212A1 (en)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1380044A (en) * 2002-05-15 2002-11-20 王先明 New type medical equipment, its control device and special-purpose nano material
CN1263432C (en) * 2003-12-03 2006-07-12 朱宏 Magnetic heat treatment therapeutic apparatus for tumour
JP2005253813A (en) * 2004-03-15 2005-09-22 Yokohama Tlo Co Ltd Mri treatment system
CN201414837Y (en) * 2009-07-09 2010-03-03 福州浩联医疗科技有限公司 Magnetic induction therapeutic machine
WO2011159913A2 (en) * 2010-06-16 2011-12-22 The Trustees Of Dartmouth College Magnetic particle heating system and method for occlusion of the fallopian tube
US20130053620A1 (en) * 2011-08-26 2013-02-28 Actium BioSystems, LLC Apparatus for the generation of an energy field for the treatment of cancer in body cavities and parts that are cavity-like
CN203763681U (en) * 2014-03-17 2014-08-13 赵峰 Magnetic-ring tumor therapeutic instrument based on X ray

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Effective date of registration: 20210922

Address after: 510000 room d423, second floor, No. 8, Huangcun Road, Tianhe District, Guangzhou, Guangdong

Applicant after: Guangdong Advanced Power Technology Co.,Ltd.

Address before: 510665 No. 4, Jiangong Road, Tianhe District, Guangzhou City, Guangdong Province

Applicant before: Sun Zhiqiang

WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20200717