CN111419933A - Traditional Chinese medicine composition for tonifying spleen and promoting appetite and external preparation and application thereof - Google Patents
Traditional Chinese medicine composition for tonifying spleen and promoting appetite and external preparation and application thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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Abstract
The invention provides a traditional Chinese medicine composition for tonifying spleen and stimulating appetite, an external preparation and application thereof, wherein the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 5-13 parts of folium artemisiae argyi, 8-15 parts of agastache rugosus, 8-15 parts of eupatorium fortunei, 8-12 parts of radix angelicae, 8-17 parts of rhizoma atractylodis, 7-15 parts of pepper, 7-15 parts of fennel and 5-13 parts of pericarpium citri reticulatae. In the formula of the invention, the rhizoma atractylodis is fragrant and can invigorate the spleen, and is a monarch drug; the agastache rugosus, the eupatorium fortunei and the angelica dahurica are used as ministerial drugs which are aromatic and damp-resolving, spleen-activating and appetizing; the dried orange peel regulates qi and stomach, and the folium artemisiae argyi, the pepper and the fennel have the effects of eliminating turbid pathogen with aromatics, and are used as adjuvant drugs; has the effects of eliminating dampness with aromatics, invigorating spleen and promoting appetite, and can remarkably improve incoordination between spleen and stomach.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for tonifying spleen and promoting appetite, and an external preparation and application thereof.
Background
Spleen-stomach disharmony with qi stagnation may cause dysfunction of the spleen and stomach, manifested as abdominal distension, stomach-hospital disturbance, poor appetite, abdominal distension after eating, borygmus, abnormal stool, wiry pulse, etc. Incoordination between the spleen and the stomach directly affects the health of people, so that people do not have spirit all day long, sleep is loved, the body is full of weakness, the tongue coating is yellow and greasy, the conditions of dry mouth, bitter taste, halitosis and the like occur, and the life quality and the working efficiency of patients are affected. However, patients of this type often feel unhindered and do not take active medication. The traditional Chinese medicine sachet and pill can be worn on person, can also be placed in a pocket, a car, a room, a pillow edge and the like, are very convenient, can be absorbed through respiratory tract or skin to play the role of preventing and treating diseases, avoids oral administration, and improves the administration conditioning enthusiasm of patients. However, the traditional Chinese medicine sachet has poor spleen strengthening and appetite stimulating effects, and the invention aims to provide a traditional Chinese medicine composition which can be prepared into traditional Chinese medicine external preparation sachets and the like to obviously improve incoordination between spleen and stomach.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine composition for invigorating spleen and promoting appetite, and an external preparation and application thereof.
The technical scheme of the invention is realized as follows: the active components of the traditional Chinese medicine composition for invigorating spleen and stimulating appetite comprise the following raw material medicines in parts by weight: 5-13 parts of folium artemisiae argyi, 8-15 parts of agastache rugosus, 8-15 parts of eupatorium fortunei, 8-12 parts of radix angelicae, 8-17 parts of rhizoma atractylodis, 7-15 parts of pepper, 7-15 parts of fennel and 5-13 parts of pericarpium citri reticulatae.
Preferably, the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 8 parts of folium artemisiae argyi, 13 parts of wrinkled gianthyssop herb, 12 parts of fortune eupatorium herb, 10 parts of dahurian angelica root, 15 parts of swordlike atractylodes rhizome, 9 parts of Chinese prickly ash, 11 parts of common fennel fruit and 10 parts of tangerine peel.
Preferably, the rhizoma atractylodis is rhizoma atractylodis.
A traditional Chinese medicine composition external preparation for strengthening spleen and stimulating appetite comprises any one of the traditional Chinese medicine compositions for strengthening spleen and stimulating appetite.
Preferably, the external preparation of the traditional Chinese medicine composition is one of sachet and pill.
The application of the traditional Chinese medicine composition in preparing the medicines for tonifying spleen and stimulating appetite.
Compared with the prior art, the invention has the beneficial effects that:
in the formula of the invention, the rhizoma atractylodis is fragrant and can invigorate the spleen, and is a monarch drug; the agastache rugosus, the eupatorium fortunei and the angelica dahurica are used as ministerial drugs which are aromatic and damp-resolving, spleen-activating and appetizing; the dried orange peel regulates qi and stomach, and the folium artemisiae argyi, the pepper and the fennel have the effects of eliminating turbid pathogen with aromatics, and are used as adjuvant drugs; has the effects of eliminating dampness with aromatics, invigorating spleen and promoting appetite, and can remarkably improve incoordination between spleen and stomach.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
The basic conditions of the main raw material drugs are described in the Chinese pharmacopoeia, the Chinese dictionary and the Chinese herbal medicine.
Agastache rugosus: [ PROPERTIES AND FLAVOUR ] pungent and slightly warm. [ GUIJING ] enters lung, spleen and stomach meridians. [ FUNCTIONS ] can promote the flow of qi, regulate the middle warmer, remove dirt, and eliminate dampness. It is used to treat common cold with summer-heat and dampness, cold and heat, headache, fullness and distention in chest and abdomen, emesis, diarrhea, malaria, dysentery, and halitosis.
Herba Eupatorii: [ PROPERTIES AND FLAVOUR ] pungent and mild. [ GUIJING ] can enter spleen, stomach and lung meridians. [ FUNCTIONS ] can dispel dampness with aromatics, activate the spleen, stimulate the appetite, relieve exterior syndrome and relieve summer-heat. Can be used for treating damp stagnation, gastric fullness, emesis, halitosis, sialorrhea, summer-heat dampness, headache, and chest distress.
Radix angelicae: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] enters stomach, large intestine and lung meridians. [ FUNCTIONS ] can dispel wind, remove dampness, relieve pain, relieve swelling, and expel pus. Can be used for treating common cold, headache, supraorbital bone pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, and pyocutaneous disease with swelling and pain.
Rhizoma atractylodis: [ PROPERTIES AND WESTERN ] is pungent, bitter and warm. [ GUIJING ] can enter spleen, stomach and liver meridians. [ FUNCTIONS ] can eliminate dampness, invigorate spleen, dispel wind, dispel cold, and improve eyesight. Can be used for treating abdominal distention, diarrhea, edema, tinea pedis, paralysis 36484m, rheumatalgia, common cold due to wind-cold evil, and night blindness.
Dried orange peel: [ PROPERTIES AND WESTERN ] is bitter, pungent and warm. [ GUIJING ] enters lung and spleen meridians. [ FUNCTIONS ] can regulate qi, invigorate spleen, eliminate dampness and resolve phlegm. Can be used for treating fullness in chest and abdomen, anorexia, vomiting, diarrhea, cough, and excessive phlegm.
Folium artemisiae argyi: [ PROPERTIES AND WESTERN PROPERTIES ] is pungent, bitter and warm; has little toxicity. [ GUIJING ] enters liver, spleen and kidney meridians. [ FUNCTIONS ] can dispel cold, alleviate pain, warm meridians and stop bleeding. Can be used for treating lower abdomen psychroalgia, irregular menstruation, infertility due to cold womb, hematemesis, epistaxis, metrorrhagia, metrostaxis, and pregnancy bleeding; it can be used for treating skin pruritus. Vinegar moxa charcoal warms the channels to stop bleeding. Can be used for treating hemorrhage due to deficiency cold.
Chinese prickly ash: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] pertains to the spleen, stomach and kidney meridians. [ FUNCTIONS ] the functional indications are warming the middle-jiao to alleviate pain, killing parasites to relieve itching. Can be used for treating abdominal psychroalgia, emesis, diarrhea, abdominal pain due to parasitic infestation, and ascariasis; it can be used for treating eczema and pruritus.
Fennel: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] enters liver, kidney, spleen and stomach meridians. [ FUNCTIONS ] can dispel cold, alleviate pain, regulate qi, and regulate stomach. Can be used for treating abdominal pain due to hernia of cold type, testis tenesmus, dysmenorrhea, cold pain of lower abdomen, abdominal distention and pain, anorexia, vomiting and diarrhea, and hydrocele of tunica vaginalis of testis. The salt fructus Foeniculi has effects of warming kidney, dispelling cold, and relieving pain. Can be used for treating abdominal pain due to hernia of cold, tenesmus of testis, and cold abdominal pain due to meridian obstruction.
Example 1
A traditional Chinese medicine composition for tonifying spleen and stimulating appetite is prepared from the following raw material medicines in parts by weight: 5 parts of folium artemisiae argyi, 8 parts of wrinkled gianthyssop herb, 15 parts of fortune eupatorium herb, 8 parts of dahurian angelica root, 17 parts of raw rhizoma atractylodis, 7 parts of pepper, 15 parts of common fennel fruit and 5 parts of dried orange peel. Pulverizing the above materials, and packaging into sachet medicinal bag to obtain the final product.
Example 2
A traditional Chinese medicine composition for tonifying spleen and stimulating appetite is prepared from the following raw material medicines in parts by weight: 13 parts of folium artemisiae argyi, 15 parts of wrinkled gianthyssop herb, 8 parts of fortune eupatorium herb, 12 parts of dahurian angelica root, 8 parts of raw rhizoma atractylodis, 15 parts of pepper, 7 parts of common fennel fruit and 13 parts of dried orange peel. Pulverizing the above materials, and packaging into sachet medicinal bag to obtain the final product.
Example 3
A traditional Chinese medicine composition for tonifying spleen and stimulating appetite is prepared from the following raw material medicines in parts by weight: 10 parts of folium artemisiae argyi, 10 parts of wrinkled gianthyssop herb, 10 parts of fortune eupatorium herb, 10 parts of dahurian angelica root, 10 parts of raw rhizoma atractylodis, 10 parts of pepper, 10 parts of common fennel fruit and 10 parts of dried orange peel. Pulverizing the above materials, and packaging into sachet medicinal bag to obtain the final product.
Example 4
A traditional Chinese medicine composition for tonifying spleen and stimulating appetite is prepared from the following raw material medicines in parts by weight: 8 parts of folium artemisiae argyi, 13 parts of wrinkled gianthyssop herb, 12 parts of fortune eupatorium herb, 10 parts of dahurian angelica root, 15 parts of swordlike atractylodes rhizome, 9 parts of Chinese prickly ash, 11 parts of common fennel fruit and 10 parts of tangerine peel. Pulverizing the above materials, and packaging into sachet medicinal bag to obtain the final product.
Comparative example 1
The comparison example is different from the example 3 in that the pepper is replaced by the kaempferia galanga with the same amount, and the common fennel is replaced by the clove with the same amount.
Wherein, the resurrectionlily rhizome: pungent and warm in nature and flavor. Meridian tropism enters stomach meridian. Move qi and warm middle energizer, promote digestion and alleviate pain. Can be used for treating fullness and distention of chest and abdomen, abdominal psychroalgia, and indigestion.
Clove: pungent and warm in nature and flavor. Meridian tropism includes spleen, stomach, lung and kidney meridians. The functions are mainly to warm the middle-jiao and descend the adverse flow of qi, tonify the kidney and strengthen yang. Can be used for treating deficiency-cold of spleen and stomach, singultus emesis, anorexia vomiting and diarrhea, psychroalgia of heart and abdomen, and sexual impotence due to kidney deficiency.
The traditional Chinese medicine sachet prepared by the method is applied to clinic:
1. basic data: 300 patients with spleen-stomach disharmony are collected, and the age is 6-50 years old. The patient has symptoms of poor appetite, easy abdominal distension or loose stool, and the like, and the syndrome differentiation is carried out by combining with the standard of the traditional Chinese medicine diagnostics. The groups were randomly divided into test group 1 to test group 6, and each group had 50 cases. The gender distribution, mean age for each group are shown in the following table:
the patients in each group have no statistical difference in age, sex and the like and are comparable.
2. The application method and the treatment course are as follows: the traditional Chinese medicine sachets of examples 1-4 and comparative example 1 and the traditional Chinese medicine sachets of the control group (main traditional Chinese medicine components: clove, nutmeg, fructus amomi, agastache rugosus, eupatorium, dried orange peel and the like) sold in the market are respectively used in the test group 1-6, and each sachet contains about 25 g of traditional Chinese medicine. The using method comprises the following steps: each person wears 1 sachet per day, smells before nose for 3-4 times every day, each time for 2-3 minutes, and puts on the edge of pillow when sleeping. The sachet is replaced 1 time every 7 days, if the sachet is affected with damp, the sachet is replaced in time. The sachet was used continuously for 1 month.
3. Criteria for judging therapeutic effects
The effect is shown: the appetite is normal, and the incoordination between the spleen and the stomach basically disappears;
the method has the following advantages: the incoordination between the spleen and the stomach is relieved;
and (4) invalidation: the incoordination between the spleen and the stomach does not improve.
4. Therapeutic results
The clinical conditions show that the traditional Chinese medicine composition has obvious treatment effect on strengthening spleen and stimulating appetite, the significant efficiency is more than 80.0%, and the total effective rate is more than 98.0%.
5. Typical cases
Medical record 1: when the traditional Chinese medicine sachet is taken with a person in the embodiment 3 of the invention, the person smells 3-4 times before the nose every day, each time lasts for 2-3 minutes, and is placed at the edge of a pillow when sleeping; the sachet was replaced 1 time every 7 days. After 1 week, the appetite improved, and after using the sachet for 2 weeks, the appetite was normal, the abdominal distention disappeared, and the tongue coating was normal.
Medical record 2: when the plum is taken by a male, the male is 29 years old, the plum is poor in appetite, is full when being eaten a little, is easy to have abdominal distension and loose stool, has a yellowish, thick and greasy tongue coating, is carried with the traditional Chinese medicine sachet in the embodiment 4 of the invention, and is put in front of the nose for smelling 3-4 times every day, each time for 2-3 minutes, and is put in the edge of the pillow when sleeping; the sachet was replaced 1 time every 7 days. After 10 days, the abdominal distension is obviously improved, the appetite is improved, and after the sachet is continuously used for 20 days, the thick and greasy tongue coating is obviously improved, the appetite is recovered to be normal, abdominal distension is not seen, and the stool is shaped.
6. And (4) safety observation: in all cases observed, no adverse reactions were observed.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (6)
1. The traditional Chinese medicine composition for tonifying spleen and stimulating appetite is characterized in that active components of the composition comprise the following raw material medicines in parts by weight: 5-13 parts of folium artemisiae argyi, 8-15 parts of agastache rugosus, 8-15 parts of eupatorium fortunei, 8-12 parts of radix angelicae, 8-17 parts of rhizoma atractylodis, 7-15 parts of pepper, 7-15 parts of fennel and 5-13 parts of pericarpium citri reticulatae.
2. The traditional Chinese medicine composition for tonifying spleen and stimulating appetite according to claim 1, which is characterized in that the active ingredients comprise the following raw material medicines in parts by weight: 8 parts of folium artemisiae argyi, 13 parts of wrinkled gianthyssop herb, 12 parts of fortune eupatorium herb, 10 parts of dahurian angelica root, 15 parts of swordlike atractylodes rhizome, 9 parts of Chinese prickly ash, 11 parts of common fennel fruit and 10 parts of tangerine peel.
3. The traditional Chinese medicine composition for tonifying spleen and stimulating appetite as claimed in claim 1, wherein the rhizoma atractylodis is raw rhizoma atractylodis.
4. A traditional Chinese medicine composition external preparation for invigorating spleen and stimulating appetite, which is characterized by comprising the traditional Chinese medicine composition for invigorating spleen and stimulating appetite according to any one of claims 1 to 3.
5. The traditional Chinese medicine composition external preparation for invigorating spleen and stimulating appetite according to claim 4, wherein the traditional Chinese medicine composition external preparation is one of sachet and pill.
6. Use of the Chinese medicinal composition of any one of claims 1 to 3 in the preparation of a medicament for invigorating spleen and stimulating appetite.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114533833A (en) * | 2022-02-25 | 2022-05-27 | 袁秀玲 | Traditional Chinese medicine composition for warming viscera and application thereof |
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| CN1081913A (en) * | 1992-08-11 | 1994-02-16 | 李长清 | " universe " bag |
| CN1119949A (en) * | 1994-12-26 | 1996-04-10 | 王天成 | Fragrant medicine bag |
| CN103007153A (en) * | 2012-11-21 | 2013-04-03 | 徐曼丽 | Health-care traditional Chinese medicine scented sachet |
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2020
- 2020-05-28 CN CN202010466826.2A patent/CN111419933A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1081913A (en) * | 1992-08-11 | 1994-02-16 | 李长清 | " universe " bag |
| CN1119949A (en) * | 1994-12-26 | 1996-04-10 | 王天成 | Fragrant medicine bag |
| CN103007153A (en) * | 2012-11-21 | 2013-04-03 | 徐曼丽 | Health-care traditional Chinese medicine scented sachet |
Non-Patent Citations (1)
| Title |
|---|
| 王力宁等: "《家庭外治助儿康》", 31 March 2017, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114533833A (en) * | 2022-02-25 | 2022-05-27 | 袁秀玲 | Traditional Chinese medicine composition for warming viscera and application thereof |
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