CN111388395A - Formula of plant shampoo capable of effectively relieving itching and removing dandruff and preparation method thereof - Google Patents
Formula of plant shampoo capable of effectively relieving itching and removing dandruff and preparation method thereof Download PDFInfo
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- CN111388395A CN111388395A CN202010327598.0A CN202010327598A CN111388395A CN 111388395 A CN111388395 A CN 111388395A CN 202010327598 A CN202010327598 A CN 202010327598A CN 111388395 A CN111388395 A CN 111388395A
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- 239000002453 shampoo Substances 0.000 title claims abstract description 45
- 208000001840 Dandruff Diseases 0.000 title claims abstract description 41
- 208000003251 Pruritus Diseases 0.000 title claims abstract description 32
- 230000007803 itching Effects 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title abstract description 10
- 241000196324 Embryophyta Species 0.000 claims abstract description 63
- 239000000203 mixture Substances 0.000 claims abstract description 38
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 13
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 13
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 13
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 34
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 33
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 24
- YIXJRHPUWRPCBB-UHFFFAOYSA-N magnesium nitrate Chemical compound [Mg+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O YIXJRHPUWRPCBB-UHFFFAOYSA-N 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 24
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- VFKZECOCJCGZQK-UHFFFAOYSA-M 3-hydroxypropyl(trimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCO VFKZECOCJCGZQK-UHFFFAOYSA-M 0.000 claims description 14
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 13
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 claims description 13
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- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 11
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- PYIDGJJWBIBVIA-UYTYNIKBSA-N lauryl glucoside Chemical compound CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PYIDGJJWBIBVIA-UYTYNIKBSA-N 0.000 claims description 11
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- OYINQIKIQCNQOX-UHFFFAOYSA-M 2-hydroxybutyl(trimethyl)azanium;chloride Chemical compound [Cl-].CCC(O)C[N+](C)(C)C OYINQIKIQCNQOX-UHFFFAOYSA-M 0.000 claims description 6
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- BOUCRWJEKAGKKG-UHFFFAOYSA-N n-[3-(diethylaminomethyl)-4-hydroxyphenyl]acetamide Chemical compound CCN(CC)CC1=CC(NC(C)=O)=CC=C1O BOUCRWJEKAGKKG-UHFFFAOYSA-N 0.000 claims description 4
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9761—Cupressaceae [Cypress family], e.g. juniper or cypress
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- A—HUMAN NECESSITIES
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Mycology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a formula of a plant shampoo capable of effectively relieving itching and removing dandruff and a preparation method thereof, and belongs to the technical field of daily cosmetic production. The plant shampoo formula comprises plant composition components, wherein the plant composition comprises the following components in parts by weight: 10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus cnidii, 8-16 parts of cacumen biotae, 8-16 parts of purslane, 8-16 parts of folium mori, 8-16 parts of fructus kochiae, 8-16 parts of houttuynia cordata, 4-12 parts of polygonum multiflorum, 4-12 parts of rehmannia glutinosa, 4-12 parts of moutan bark, 4-12 parts of black bean coat, 2-5 parts of rhizoma zingiberis, 3-10 parts of lavender, 3-10 parts of liquorice and 2-5 parts of broadleaf holly leaf. The anti-dandruff and anti-itching traditional Chinese medicine is prepared by compounding plant components, has good compatibility and good efficacy, improves the anti-dandruff and anti-itching curative effect, is safe and reliable, has mild performance and no adverse reaction, is simple in preparation method, does not need complex production equipment, has moderate cost, and is suitable for large-scale production.
Description
Technical Field
The invention belongs to the technical field of daily cosmetic production, and particularly relates to a formula of a plant shampoo capable of effectively relieving itching and removing dandruff and a preparation method thereof.
Background
Itching and scurf often affect people's life and work as common problems. Dandruff is keratinocyte desquamated from scalp, under normal conditions, the keratinocyte desquamation is little and slow, and can not be obviously seen, but under certain stimulation, a great amount of immature keratinocyte is generated, and agglomeration and desquamation are formed, so that a snowflake phenomenon, namely dandruff, is formed. Dandruff is divided into physiological dandruff and pathological dandruff, physiological dandruff is generally found in dry dandruff, another oily dandruff, scalp and hair have greasy feeling, and is common in infants. Pathological dandruff refers to inflammation of the scalp caused by bacterial infection, fungal infection or other physicochemical injury.
The itching relieving and scurf removing agent is used in hair washing and caring products as early as 70 years, and has been developed for nearly 30 years from the first sulfur, salicylic acid to selenium disulfide, undecylenic acid derivatives, z tincture and the like. The original sulfur and salicylic acid have poor effect, although the bactericidal effect is achieved, the irritation is large, the skin is damaged, and research develops the itching-relieving and dandruff-removing agents such as selenium disulfide and the like, although the itching-relieving and dandruff-removing agents have better dandruff-removing effect than salicylic acid and the like, the solubility is poor, the product performance is unstable, active substances are easy to precipitate, the shampoo production process is complex, the application is limited to a certain extent, the shampoo is safer, and due to strong degreasing force, sebaceous gland atrophy can be caused after long-time use, the sebum secretion is reduced, surface cell aging is accelerated, dandruff is increased, dry and yellow hair can be caused, and the eye mucosa is greatly damaged due to strong irritation. Therefore, the comprehensive evaluation of itching relieving and dandruff removing is not ideal.
At present, many commercially available shampoos can effectively remove oil and dandruff on hair, but most of them are mainly prepared by adding chemical agents, such as ZPT/OCT chemical antidandruff agents, antioxidants, western medicines, hormones, antibacterial agents, salicylic acid, minoxidil, finasteride tablets, zinc pyrithione (ZTP), piroctone Olamine (OCT), climbazole, ketoconazole and the like, and most of these chemical agent raw materials have irritation on skin and scalp. The long-term use of the scalp shampoo can cause the dependence of the scalp on chemical drugs, and simultaneously, the scalp antibacterial, antiviral and antiviral immunity is continuously reduced.
In view of the above, the invention provides a formula of a plant shampoo capable of effectively relieving itching and removing dandruff and a preparation method thereof, which can effectively solve various scalp problems caused by adding chemical drugs into the shampoo and achieve the purposes of ecological and healthy itching relieving, dandruff removing, safety and harmlessness.
Disclosure of Invention
In order to solve the technical problems, the invention provides a plant shampoo formula capable of effectively relieving itching and removing dandruff and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the plant shampoo formula for relieving itching and removing dandruff comprises plant composition components, wherein the plant composition comprises the following components in parts by weight:
10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus cnidii, 8-16 parts of cacumen biotae, 8-16 parts of purslane, 8-16 parts of folium mori, 8-16 parts of fructus kochiae, 8-16 parts of houttuynia cordata, 4-12 parts of polygonum multiflorum, 4-12 parts of rehmannia glutinosa, 4-12 parts of moutan bark, 4-12 parts of black bean coat, 2-5 parts of rhizoma zingiberis, 3-10 parts of lavender, 3-10 parts of liquorice and 2-5 parts of broadleaf holly leaf.
Preferably, the weight ratio of the black soya bean coat to the liquorice to the broadleaf holly leaf is 7-9:5-6:3-4, and more preferably 8:5.5: 3.5.
Wherein,
the weight percentage of the plant composition in the plant shampoo formula is 60-80%, preferably 65%.
The plant shampoo formula also comprises phase A, wherein the phase A comprises allantoin, laureth ammonium sulfate and cocamidopropyl betaine.
The plant shampoo formula also comprises a phase B, wherein the phase B comprises hydroxypropyl methylcellulose, citric acid, guar hydroxypropyl trimonium chloride, cetyl alcohol, cocoamide, ethylene glycol distearate, polyquaternium-10, lauryl glucoside and decyl glucoside.
The above plant shampoo formulation further comprises phase C comprising amodimethicone/C12-14 secondary alkanol polyether-9/tridecanol polyether-6/glycerin, hydroxypropyltrimonium chloride hydrolyzed wheat protein, menthol, hydantoin, and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate.
The plant shampoo formula comprises the following components in percentage by weight:
60-80% of plant composition;
phase A: allantoin 0.08-0.12%, laureth sulfate ammonium 3.0-4.0%, laureth sulfate ammonium 1.5-1.9%, and cocamidopropyl betaine 1.5-2.0%;
phase B: hydroxypropyl methylcellulose 0.35-0.45%, citric acid 0.01-0.03%, guar hydroxypropyl trimethyl ammonium chloride 0.21-0.25%, cetyl alcohol 0.19-0.23%, cocoamide 0.9-1.2%, ethylene glycol distearate 0.85-1.15%, polyquaternium-100.06-0.10%, lauryl glucoside 4.0-7.0% and decyl glucoside 1.5-2.5%;
and C phase: aminoterminal polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecyl alcohol polyether-6/glycerol 0.10-0.14%, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein 0.15-0.17%, menthol 0.05-0.07%, hydantoin 0.25-0.35%, and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate 0.035-0.037%;
and the balance water.
Preferably, the plant shampoo formula comprises the following components in percentage by weight:
65% of plant composition;
phase A: allantoin 0.1%, laureth sulfate ammonium 3.5%, laureth sulfate ammonium 1.7% and cocamidopropyl betaine 1.8%;
phase B: hydroxypropyl methylcellulose 0.4%, citric acid 0.02%, guar hydroxypropyl trimonium chloride 0.23%, whale 5 cetyl alcohol 0.21%, cocamide MEA 1.1%, ethylene glycol distearate 1%, polyquaternium-100.08%, lauryl glucoside 5% and decyl glucoside 2.0%;
and C phase: aminoterminal polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecyl alcohol polyether-6/glycerol 0.12%, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein 0.16%, menthol 0.06%, DMDM hydantoin 0.3% and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate 0.036%;
and the balance water.
In addition, the invention also provides a method for preparing the plant shampoo formula, which comprises the following steps:
s1, an extraction method of the plant composition: pulverizing radix Sophorae Flavescentis, fructus Cnidii, folium Platycladi, herba Portulacae, folium Mori, Kochiae fructus, herba Houttuyniae, Polygoni Multiflori radix, rehmanniae radix, cortex moutan, semen Sojae Atricolor coat, Zingiberis rhizoma, Lavender, Glycyrrhrizae radix and Folum Ilicis, decocting in water to obtain plant composition extractive solution;
s2, adding allantoin, ammonium laureth sulfate and cocamidopropyl betaine in formula ratio into the extract obtained in the step S1, and stirring and homogenizing to obtain a phase A mixed solution;
s3, adding hydroxypropyl methyl cellulose, citric acid, guar gum hydroxypropyl trimethyl ammonium chloride, cetyl alcohol, cocamide, ethylene glycol distearate, polyquaternium-10, lauryl glucoside and decyl glucoside in formula amounts to the A phase mixed solution obtained in the step S2 in sequence, stirring and preserving heat to obtain an AB phase mixed solution;
s4, cooling the AB phase mixed solution obtained in the step S3, sequentially adding amino-terminated polydimethylsiloxane/C12-14 sec-alkanol polyether-9/tridecanol polyether-6/glycerol, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein, menthol, hydantoin and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate in a formula amount, and stirring to obtain ABC phase mixed solution;
s5, cooling the ABC phase mixed liquid obtained in the step S4, and filtering to obtain the plant shampoo formula.
Wherein,
the pulverization in the step S1 is to pulverize to a particle size of 10-20 μm; the water-adding decoction comprises the following steps: adding water into the plant composition according to the mass ratio of 1:2-3, and decocting at 90-100 deg.C for 3.5-4.5 h.
In step S2, the stirring and homogenizing step includes: heating to 80-85 deg.C at rotation speed of 33-37r/min, stirring and homogenizing for 4-6 min; in the step S3, the stirring and heat preservation are as follows: keeping the temperature of 80-85 ℃ for 30min at the rotating speed of 33-37 r/min; in step S4, the cooling is: cooling to 43-47 ℃, wherein the stirring is as follows: stirring at 28-32r/min for 20-25 min; in step S5, the filtering is to pass through a 70-90 mesh sieve.
The invention has the beneficial effects that:
(1) the invention is prepared by compounding plant components such as lightyellow sophora root, common cnidium fruit, Chinese arborvitae twig, purslane, mulberry leaf, belvedere fruit, heartleaf houttuynia herb, tuber fleeceflower root, rehmannia root, tree peony bark, black bean coat, dried ginger, lavender, liquorice and ilex latifolia thumb, and is modified into the following components: has good compatibility and efficacy, and greatly improves the curative effect of removing dandruff and relieving itching.
(2) The plant shampoo disclosed by the invention takes natural plants as main components, is safe and reliable, mild in performance, rich in foam and free of adverse reaction.
(3) The preparation method is simple, does not need complex production equipment, has moderate cost and is suitable for large-scale production.
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention.
Before the present embodiments are further described, it is to be understood that the scope of the invention is not limited to the particular embodiments described below; it is also to be understood that the terminology used in the examples is for the purpose of describing particular embodiments only, and is not intended to limit the scope of the present invention.
When numerical ranges are given in the examples, it is understood that both endpoints of each of the numerical ranges and any value therebetween can be selected unless the invention otherwise indicated. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
The sources of the raw materials used in the present invention are not limited, and the raw materials used in the present invention are all those commonly available in the art unless otherwise specified. Of these, aminoterminated polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecyl polyether-6/glycerol, available from Michigan advanced materials (Nantong) Inc., under the trade designation Silsoft AM 1020N; water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate, available from toler specialty chemicals (zhenjiang) ltd under the trade name Microcare CM. Both suppliers of raw materials are Guangzhou Liuhao trade development Limited.
Examples 1 to 7
The plant shampoo formula for relieving itching and removing dandruff comprises the following components in percentage by weight:
65% of plant composition;
phase A: allantoin 0.1%, laureth sulfate ammonium 3.5%, laureth sulfate ammonium 1.7% and cocamidopropyl betaine 1.8%;
phase B: hydroxypropyl methylcellulose 0.4%, citric acid 0.02%, guar hydroxypropyl trimonium chloride 0.23%, whale 5 cetyl alcohol 0.21%, cocamide MEA 1.1%, ethylene glycol distearate 1%, polyquaternium-100.08%, lauryl glucoside 5% and decyl glucoside 2.0%;
and C phase: aminoterminal polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecyl alcohol polyether-6/glycerol 0.12%, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein 0.16%, menthol 0.06%, DMDM hydantoin 0.3% and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate 0.036%;
and the balance water.
The components and amounts of the plant compositions of examples 1-7 are shown in Table 1.
TABLE 1 Components and amounts of the botanical compositions of examples 1-7
The preparation method of the plant shampoo formula comprises the following steps:
s1, an extraction method of the plant composition: pulverizing radix Sophorae Flavescentis, fructus Cnidii, folium Platycladi, herba Portulacae, folium Mori, Kochiae fructus, herba Houttuyniae, Polygoni Multiflori radix, rehmanniae radix, cortex moutan, semen Sojae Atricolor coat, Zingiberis rhizoma, Lavender, Glycyrrhrizae radix and Folum Ilicis into powder with particle diameter of 15 μm, adding water at a mass ratio of 1:2, and decocting at 100 deg.C for 4 hr to obtain plant composition extractive solution;
s2, adding allantoin, ammonium laureth sulfate and cocamidopropyl betaine according to the formula ratio into the extract obtained in the step S1 in sequence, heating to 80-85 ℃ at the rotation speed of 35r/min, and stirring and homogenizing for 5min to obtain a phase A mixed solution;
s3, adding hydroxypropyl methyl cellulose, citric acid, guar gum hydroxypropyl trimethyl ammonium chloride, cetyl alcohol, cocamide, ethylene glycol distearate, polyquaternium-10, lauryl glucoside and decyl glucoside in formula amounts sequentially into the A phase mixed solution obtained in the step S2, and preserving heat for 30min at the rotating speed of 35r/min and the temperature of 80-85 ℃ to obtain an AB phase mixed solution;
s4, cooling the AB phase mixed solution obtained in the step S3 to 45 ℃, sequentially adding amino-terminated polydimethylsiloxane/C12-14 sec-alkanol polyether-9/tridecanol polyether-6/glycerol, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein, menthol, hydantoin and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate according to the formula amount, and stirring for 20min at 30r/min to obtain ABC phase mixed solution;
s5, cooling the ABC phase mixed liquid obtained in the step S4 to 38 ℃, and sieving the ABC phase mixed liquid with a 80-mesh sieve to obtain the plant shampoo formula.
Example 8
The difference between the present embodiment and embodiment 5 is that the plant shampoo formulation comprises the following components in percentage by weight:
60% of plant composition;
phase A: allantoin 0.12%, laureth sulfate ammonium 4%, laureth sulfate ammonium 1.9% and cocamidopropyl betaine 2%;
phase B: hydroxypropyl methylcellulose 0.45%, citric acid 0.03%, guar hydroxypropyl trimethyl chloride 0.25%, cetyl alcohol 0.23%, cocamide MEA 1.2%, ethylene glycol distearate 1.15%, polyquaternium-100.1%, lauryl glucoside 7% and decyl glucoside 2.5%;
and C phase: aminoterminal polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecyl alcohol polyether-6/glycerol 0.14%, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein 0.17%, menthol 0.07%, DMDM hydantoin 0.35% and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate 0.037%;
and the balance water.
Example 9
The difference between the present embodiment and embodiment 5 is that the plant shampoo formulation comprises the following components in percentage by weight:
80% of plant composition;
phase A: allantoin 0.08%, laureth sulfate ammonium 3%, laureth sulfate ammonium 1.5% and cocamidopropyl betaine 1.5%;
phase B: hydroxypropyl methylcellulose 0.35%, citric acid 0.01%, guar hydroxypropyl trimethyl chloride 0.21%, cetyl alcohol 0.19%, cocamide MEA 0.9%, ethylene glycol distearate 0.85%, polyquaternium-100.06%, lauryl glucoside 4% and decyl glucoside 1.5%;
and C phase: amino-terminated polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecanol polyether-6/glycerol 0.10%, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein 0.15%, menthol 0.05%, DMDM hydantoin 0.25% and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate 0.035%;
and the balance water.
Comparative example 1
This comparative example differs from example 5 in that: the plant composition does not contain black bean coat.
Comparative example 2
This comparative example differs from example 5 in that: the plant composition does not contain Glycyrrhrizae radix.
Comparative example 3
This comparative example differs from example 5 in that: the plant composition does not contain Folum Ilicis.
Comparative example 4
This comparative example differs from example 5 in that: the weight parts of the black soya bean coat, the liquorice and the broadleaf holly leaf in the plant composition are respectively 13 parts, 3 parts and 6 parts.
Examples of the experiments
Animal experiments
150 healthy guinea pigs with the weight of 250-. Using the drugs of examples 1-9, comparative examples 1-4, commercially available dandruff-removing and itching-relieving shampoo, and distilled water (blank group) in this order, the dorsal hairs of the right hind paw were shaved off, the corresponding drug was applied once, 0.1 g/stick, 1h later, the shaved part was scratched with a coarse sandpaper, and the area was about 1cm2The drug is applied again for 1 time, 0.01% of histamine phosphate is dripped at the wound surface after 10min, the dosage of histamine phosphate is 0.05m L/mouse, and the concentrations of histamine phosphate are gradually increased by 0.01%, 0.02%, 0.03% and 0.04% every 3min until the guinea pig licks the right hind paw, the total amount of histamine phosphate is the scratchiness threshold when the right hind paw is licked, and the statistical results are shown in Table 2.
Table 2.
The test results in table 2 show that the inventive shampoo can significantly improve the threshold value of histamine phosphate for itching of guinea pigs, and has significant antipruritic effect. Especially, the itching relieving effect is best when the weight ratio of the black soya bean coat to the liquorice to the broadleaf holly leaf is 5-6:3.5-4.5: 2-3. The comparative example group and the commercial dandruff-removing and itching-relieving shampoo group also have a certain itching-relieving effect, but the invention has better itching-relieving effect compared with the former.
Volunteer experiment
840 volunteers with scalp itching-prone symptoms are selected, aged 18-65 years and randomly divided into 14 groups, 60 persons in each group are respectively used for washing hair once a day with the same time length each time and continuously used for 7 days by using the prepared examples, comparative examples and the commercially available dandruff-removing and itching-relieving shampoo, and the using effects of the volunteers are observed and counted, and the results are shown in table 3.
The curative effect standard is as follows: the effect is shown: the scalp is no longer itchy; the method has the following advantages: the scalp pruritus symptom is reduced, and the interval time is prolonged; and (4) invalidation: the symptoms of scalp itching are not improved. Effective rate (effective + significant) x 100/total number of people.
Table 3.
840 volunteers with dandruff symptoms are selected, aged 18-65 years and randomly divided into 14 groups, 60 persons in each group use the prepared examples, comparative examples and the commercially available dandruff-removing and itching-relieving shampoo respectively, the hair is washed once a day, the time duration of each time is the same, after the shampoo is continuously used for 7 days, the using effects of the volunteers are observed and counted, and the results are shown in table 4.
The curative effect standard is as follows: the effect is shown: dandruff is basically disappeared; the method has the following advantages: dandruff symptoms are significantly reduced; and (4) invalidation: dandruff symptoms were not improved. Effective rate (effective + significant) x 100/total number of people.
Table 4.
As can be seen from the table 3, the invention has good antipruritic effect, the effective rate of the invention on scalp itch reaches 100%, wherein, the black soya bean coat, the liquorice and the broadleaf holly leaf have synergistic effect, and the significant efficiency is obviously improved when the weight ratio of the black soya bean coat, the liquorice and the broadleaf holly leaf is 7-9:5-6: 3-4.
As can be seen from Table 4, the invention has good anti-dandruff curative effect, the effective rate for anti-dandruff reaches 100%, wherein, the black soya bean coat, the liquorice and the broadleaf holly leaf have synergistic effect, and the significant efficiency is obviously improved when the weight ratio of the black soya bean coat, the liquorice and the broadleaf holly leaf is 5-6:3.5-4.5: 2-3.
In conclusion, the plant shampoo disclosed by the invention has the advantages that the excellent itching relieving and dandruff removing effects can be realized by compounding the plant components such as the lightyellow sophora root, the common cnidium fruit, the Chinese arborvitae twig, the purslane, the mulberry leaf, the belvedere fruit, the heartleaf houttuynia herb, the tuber fleeceflower root, the rehmannia root, the tree peony bark, the black bean coat, the dried ginger, the lavender, the liquorice and the broadleaf holly leaf, and the prepared plant shampoo takes natural plants as main components, is safe and reliable, is mild in. Meanwhile, the preparation method is simple, does not need complex production equipment, has moderate cost and is suitable for large-scale production.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (10)
1. A plant shampoo formula capable of effectively relieving itching and removing dandruff is characterized by comprising plant composition components;
the plant composition comprises the following components in parts by weight:
10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus cnidii, 8-16 parts of cacumen biotae, 8-16 parts of purslane, 8-16 parts of folium mori, 8-16 parts of fructus kochiae, 8-16 parts of houttuynia cordata, 4-12 parts of polygonum multiflorum, 4-12 parts of rehmannia glutinosa, 4-12 parts of moutan bark, 4-12 parts of black bean coat, 2-5 parts of rhizoma zingiberis, 3-10 parts of lavender, 3-10 parts of liquorice and 2-5 parts of broadleaf holly leaf.
2. The plant shampoo formula according to claim 1, wherein the weight ratio of the black soya bean coat to the liquorice to the broadleaf holly leaf is 7-9:5-6: 3-4.
3. The plant shampoo formulation according to claim 1, wherein the plant composition comprises 60-80% by weight of the plant shampoo formulation.
4. The plant shampoo formulation according to claim 1, further comprising phase a comprising allantoin, ammonium laureth sulfate, and cocamidopropyl betaine.
5. The botanical shampoo formulation as defined in claim 1 further comprising phase B comprising hydroxypropyl methylcellulose, citric acid, guar hydroxypropyltrimonium chloride, cetyl alcohol, cocamide, ethylene glycol distearate, polyquaternium-10, lauryl glucoside, and decyl glucoside.
6. The botanical shampoo formulation as in claim 1 further comprising a phase C comprising amodimethicone/C12-14 sec-alkanolpolyether-9/trideceth-6/glycerin, hydroxypropyltrimonium chloride hydrolyzed wheat protein, menthol, hydantoin, and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate.
7. The plant shampoo formulation according to any one of claims 1 to 6, comprising the following components in percentage by weight:
60-80% of plant composition;
phase A: allantoin 0.08-0.12%, laureth sulfate ammonium 3.0-4.0%, laureth sulfate ammonium 1.5-1.9%, and cocamidopropyl betaine 1.5-2.0%;
phase B: hydroxypropyl methylcellulose 0.35-0.45%, citric acid 0.01-0.03%, guar hydroxypropyl trimethyl ammonium chloride 0.21-0.25%, cetyl alcohol 0.19-0.23%, cocoamide 0.9-1.2%, ethylene glycol distearate 0.85-1.15%, polyquaternium-100.06-0.10%, lauryl glucoside 4.0-7.0% and decyl glucoside 1.5-2.5%;
and C phase: aminoterminal polydimethylsiloxane/C12-14 secondary alkanol polyether-9/tridecyl alcohol polyether-6/glycerol 0.10-0.14%, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein 0.15-0.17%, menthol 0.05-0.07%, hydantoin 0.25-0.35%, and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate 0.035-0.037%;
and the balance water.
8. A method for preparing a plant shampoo formulation according to any of claims 1 to 6, comprising the steps of:
s1, an extraction method of the plant composition: pulverizing radix Sophorae Flavescentis, fructus Cnidii, folium Platycladi, herba Portulacae, folium Mori, Kochiae fructus, herba Houttuyniae, Polygoni Multiflori radix, rehmanniae radix, cortex moutan, semen Sojae Atricolor coat, Zingiberis rhizoma, Lavender, Glycyrrhrizae radix and Folum Ilicis, decocting in water to obtain plant composition extractive solution;
s2, adding allantoin, ammonium laureth sulfate and cocamidopropyl betaine in formula ratio into the extract obtained in the step S1, and stirring and homogenizing to obtain a phase A mixed solution;
s3, adding hydroxypropyl methyl cellulose, citric acid, guar gum hydroxypropyl trimethyl ammonium chloride, cetyl alcohol, cocamide, ethylene glycol distearate, polyquaternium-10, lauryl glucoside and decyl glucoside in formula amounts to the A phase mixed solution obtained in the step S2 in sequence, stirring and preserving heat to obtain an AB phase mixed solution;
s4, cooling the AB phase mixed solution obtained in the step S3, sequentially adding amino-terminated polydimethylsiloxane/C12-14 sec-alkanol polyether-9/tridecanol polyether-6/glycerol, hydroxypropyl trimethyl ammonium chloride hydrolyzed wheat protein, menthol, hydantoin and water/methylchloroisothiazolinone/methylisothiazolinone/magnesium chloride/magnesium nitrate in a formula amount, and stirring to obtain ABC phase mixed solution;
s5, cooling the ABC phase mixed liquid obtained in the step S4, and filtering to obtain the plant shampoo formula.
9. The method according to claim 8, wherein the pulverization in step S1 is carried out to a particle size of 10 to 20 μm; the water-adding decoction comprises the following steps: adding water into the plant composition according to the mass ratio of 1:2-3, and decocting at 90-100 deg.C for 3.5-4.5 h.
10. The method of claim 9, wherein the stirring and homogenizing in step S2 is: heating to 80-85 deg.C at rotation speed of 33-37r/min, stirring and homogenizing for 4-6 min; in the step S3, the stirring and heat preservation are as follows: keeping the temperature of 80-85 ℃ for 30min at the rotating speed of 33-37 r/min; in step S4, the cooling is: cooling to 43-47 ℃, wherein the stirring is as follows: stirring at 28-32r/min for 20-25 min; in step S5, the filtering is to pass through a 70-90 mesh sieve.
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CN112022771A (en) * | 2020-09-22 | 2020-12-04 | 沧州明辰生物科技有限公司 | Anti-dandruff shampoo and preparation method thereof |
CN115998660A (en) * | 2022-12-30 | 2023-04-25 | 广州市勇辉精细化工有限公司 | Anti-dandruff itching-relieving shampoo containing plant formula and preparation method thereof |
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CN115998660A (en) * | 2022-12-30 | 2023-04-25 | 广州市勇辉精细化工有限公司 | Anti-dandruff itching-relieving shampoo containing plant formula and preparation method thereof |
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