CN111387485A - 一种用于慢性胰腺炎患者的医用营养粉及制备方法 - Google Patents
一种用于慢性胰腺炎患者的医用营养粉及制备方法 Download PDFInfo
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Abstract
本发明公开了一种用于慢性胰腺炎患者的医用营养粉及制备方法,涉及医用食品技术领域,包含如下重量份的组份:蛋白质类物质135‑1075份、脂肪类物质55‑435份、碳水化合物218‑1742份、复合矿物质65‑516份、复合维生素5‑40份、牛磺酸0.4‑3.2份、单双甘油脂肪酸酯0.5‑4份、核苷酸0.09‑0.72份、左旋肉碱0.06‑0.48份、复合增稠剂9‑72份、香草香精1‑8份、阿斯巴甜0.3‑2.2份;所述的碳水化合物包含麦芽糊精135‑1080份、结晶果糖5‑40份、低聚半乳糖5‑40份、低聚异麦芽糖5‑40份。本发明所述配方食品富含中链脂肪酸,中链脂肪酸吸收无需脂肪酶、甘油三酯再合成便能被吸收,适用于慢性胰腺炎这类脂肪消化吸收不良的患者。
Description
技术领域
本发明涉及医用食品技术领域,具体为一种用于慢性胰腺炎患者的医用营养粉及制备方法。
背景技术
医用食品,全称特殊医学用途配方食品(foods for special medical purposes,FSMP),特殊医学用途配方食品是为了满足进食受限、消化吸收障碍、代谢紊乱或特定疾病状态人群对营养素或膳食的特殊需要,专门加工配制而成的配方食品。该类产品必须在医生或临床营养师指导下,单独食用或与其他食品配合食用。近年来,我国相继出台了《预包装特殊膳食用食品标签》、《特殊医学用途配方食品通则》、《食品安全国家标准特殊医学用途配方食品良好生产规范》、《特殊医学用途配方食品注册管理办法》等几项国家标准,充分说明国家对这项新产业的高度重视。所以,在国家的重视、标准法规逐步完善、行业的共同努力下,特医行业的发展将迎来新的发展。
慢性胰腺炎是由吸烟、酗酒、自身免疫因素、主胰管梗阻等导致胰腺组织炎症细胞浸润、纤维化和胰腺功能不可逆损害的疾病。其主要临床表现为反复腹痛及由胰腺内外分泌功能紊乱引起的脂肪泻、营养不良、糖耐量异常等。因此,与健康者比较,慢性胰腺炎患者生活质量明显下降,病死率增加。
慢性胰腺炎患者胰腺外分泌功能不足可导致其营养不良,并可出现体重减轻、肌肉萎缩、骨质减少、骨质疏松及各种维生素、微量营养素缺乏等表现。有研究表明,慢性胰腺炎患者胰腺外分泌功能不足会增加其死亡风险。因此,给予慢性胰腺炎患者营养支持是非常必要的,所以亟需一种针对于肌肉衰减症患者的营养粉。
发明内容
本发明的目的在于提供一种用于慢性胰腺炎患者的医用营养粉及制备方法。
为实现上述目的,本发明提供如下技术方案:
一种用于慢性胰腺炎患者的医用营养粉,包含如下重量份的组份:蛋白质类物质135-1075份、脂肪类物质55-435份、碳水化合物218-1742份、复合矿物质65-516份、复合维生素5-40份、牛磺酸0.4-3.2份、单双甘油脂肪酸酯0.5-4份、核苷酸0.09-0.72份、左旋肉碱0.06-0.48份、复合增稠剂9-72份、香草香精1-8份、阿斯巴甜0.3-2.2份;
所述的碳水化合物包含麦芽糊精135-1080份、结晶果糖5-40份、低聚半乳糖5-40份、低聚异麦芽糖5-40份。
进一步的,所述的蛋白质包含大豆分离蛋白40-320份、全脂奶粉40-320份、牛初乳2-16份、大豆低聚肽7.5-60份、水解乳清蛋白30-240份、鱼胶原蛋白肽7.5-60粉、海洋鱼低聚肽7.5-60份、L-精氨酸20-160份、L-谷氨酰胺20-160份。
进一步的,所述的脂肪包含紫苏油粉4.4-35份、椰子油粉19-152份、大豆油粉50-400份、橄榄油粉19-152份、中链甘油三酯粉2.5-20份。
进一步的,所述的复合维生素包括维生素A0.03-0.24份、维生素D30.02-0.16份、维生素E0.045-0.36份、维生素K10.004-0.032份、维生素B10.005-0.04份、维生素B20.005-0.04份、维生素B60.005-0.04份、维生素B120.001-0.008份、L-抗坏血酸钠0.7-5.8份、D-泛酸钙0.015-0.12份、叶酸0.001-0.008份、烟酰胺0.01-0.08份、氯化胆碱2.5-20份、D-生物素0.0045-0.036份、肌醇1.65-13.2份。
进一步的,所述的复合矿物质包括柠檬酸钙5-40份、L-乳酸钙5-40份、磷酸二氢钠5-40份、柠檬酸钠15-120份、葡萄糖酸镁12-92份、葡萄糖酸亚铁0.2-1.6份、葡萄糖酸锌0.25-2份、葡萄糖酸钾22.5-180份、***钠0.0006-0.0046份、碘化钾0.0004-0.0032份、无水硫酸铜0.0125-0.1份、葡萄糖酸锰0.0625-0.5份。
进一步的,所述的复合增稠剂包括卡拉胶3-24份、瓜尔胶3.5-28份、***胶2.5-20份。
一种用于慢性胰腺炎患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和去除无水硫酸铜后的复合矿物质;
预混料c:包括上述脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物、香草香精、阿斯巴甜、牛磺酸、左旋肉碱、核苷酸、复合维生素以及无水硫酸铜;
所述部分碳水化合物为一部分麦芽糊精、菊粉、低聚半乳糖、低聚异麦芽糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1-2:1-2:1-2;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50-80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为20-30r/min,最高/最低频率为50/5HZ,时间为50-80min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌50-80min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20-30r/min,搅拌5-30min;然后向预混料a、b中加入适量40%酒精粘合剂溶液500-1200g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为10-30r/min,分散10-20r/min,加入部分酒精,喷加酒精的频率为2-8s/次,每次喷加酒精10-30g,间隔5-10s,加入后搅拌5-15min;其次设置搅拌速度为20-50r/min,分散20-50r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌5-20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料、和预混料d的原辅料投入混料斗中进行预混,设置转速40-80r/min,时间为50-80min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40-80r/min,混合100-150min,得到成品。
与现有技术相比,本发明的有益效果是:本产品配方根据GB29922-2016《食品安全国家标准特殊医学用途配方食品通则》的严格要求,并将多种优质蛋白质及脂肪,人体所需的维生素、矿物质结合起来,在不刺激胰腺分泌的前提下有效补充患者缺乏的各种营养,又能缓解患者腹痛,维护胰腺功能。
本发明所述配方食品富含中链脂肪酸,中链脂肪酸吸收无需脂肪酶、甘油三酯再合成便能被吸收,适用于慢性胰腺炎这类脂肪消化吸收不良的患者。
本发明所述配方食品的蛋白质来源于优质蛋白,乳清蛋白粉可以明显提高患者的营养疗效、改善预后、降低感染发生率、并且可以缩短住院时间、减少住院费用。海洋鱼低聚肽、鱼胶原蛋白肽等小分子肽,能为人体提供不同形式的氮源,易于患者消化吸收。
本产品中富含低聚异麦芽糖,能明显维持肠道的正常菌群,抑制致病菌的生长,防止胃肠吸收障碍。低聚半乳糖是人体肠道中双歧杆菌、嗜酸乳酸杆菌等有益菌极好的营养源和有效的增殖因子,可以改善患者肠道内的消化吸收功能。
本发明所述配方食品富含L-精氨酸、L-谷氨酰胺等,有利于提高蛋白质的合成,预防分解代谢,增加机体免疫能力,促进细胞组织的修复。
本发明中包含人体不可缺少的牛磺酸,可提高机体的免疫能力,同时含有核苷酸等免疫营养素,并提高机体抗氧化能力、抗辐射能力以及对外界的应激能力。
具体实施方式
下面对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1:
一种用于慢性胰腺炎患者的医用营养粉,包含如下重量份的组份:蛋白质类物质135份、脂肪类物质55份、碳水化合物218份、复合矿物质65份、复合维生素5份、牛磺酸0.4份、单双甘油脂肪酸酯0.5份、核苷酸0.09份、左旋肉碱0.06份、复合增稠剂9份、香草香精1份、阿斯巴甜0.3份;
所述的蛋白质类物质包含大豆分离蛋白40份、全脂奶粉40份、牛初乳2份、大豆低聚肽7.5份、水解乳清蛋白30份、鱼胶原蛋白肽7.5粉、海洋鱼低聚肽7.5份、L-精氨酸20份、L-谷氨酰胺20份。
所述的脂肪类物质包含紫苏油粉4.4份、椰子油粉19份、大豆油粉50份、橄榄油粉19份、中链甘油三酯粉2.5份。
所述的碳水化合物包含麦芽糊精135份、结晶果糖5份、低聚半乳糖5份、低聚异麦芽糖5份。
所述的复合维生素包括维生素A0.03份、维生素D30.02份、维生素E0.045份、维生素K10.004份、维生素B10.005份、维生素B20.005份、维生素B60.005份、维生素B120.001份、L-抗坏血酸钠0.7份、D-泛酸钙0.015份、叶酸0.001份、烟酰胺0.01份、氯化胆碱2.5份、D-生物素0.0045份、肌醇1.65份。
所述的复合矿物质包括柠檬酸钙5份、L-乳酸钙5份、磷酸二氢钠5份、柠檬酸钠15份、葡萄糖酸镁12份、葡萄糖酸亚铁0.2份、葡萄糖酸锌0.25份、葡萄糖酸钾22.5份、***钠0.0006份、碘化钾0.0004份、无水硫酸铜0.0125份、葡萄糖酸锰0.0625份。
所述的复合增稠剂包括卡拉胶3份、瓜尔胶3.5份、***胶2.5份。
实施例2:
一种用于慢性胰腺炎患者的医用营养粉,包含如下重量份的组份:蛋白质类物质1075份、脂肪类物质435份、碳水化合物1742份、复合矿物质516份、复合维生素40份、牛磺酸3.2份、单双甘油脂肪酸酯4份、核苷酸0.72份、左旋肉碱0.48份、复合增稠剂72份、香草香精8份、阿斯巴甜2.2份;
所述的蛋白质类物质包含大豆分离蛋白320份、全脂奶粉320份、牛初乳16份、大豆低聚肽60份、水解乳清蛋白240份、鱼胶原蛋白肽60粉、海洋鱼低聚肽60份、L-精氨酸160份、L-谷氨酰胺160份。
所述的脂肪类物质包含紫苏油粉35份、椰子油粉152份、大豆油粉400份、橄榄油粉152份、中链甘油三酯粉20份。
所述的碳水化合物包含麦芽糊精1080份、结晶果糖40份、低聚半乳糖40份、低聚异麦芽糖40份。
所述的复合维生素包括维生素A0.24份、维生素D30.16份、维生素E0.36份、维生素K10.032份、维生素B10.04份、维生素B20.04份、维生素B60.04份、维生素B120.008份、L-抗坏血酸钠5.8份、D-泛酸钙0.12份、叶酸0.008份、烟酰胺0.08份、氯化胆碱20份、D-生物素0.036份、肌醇13.2份。
所述的复合矿物质包括柠檬酸钙40份、L-乳酸钙40份、磷酸二氢钠40份、柠檬酸钠120份、葡萄糖酸镁92份、葡萄糖酸亚铁1.6份、葡萄糖酸锌2份、葡萄糖酸钾180份、***钠0.0046份、碘化钾0.0032份、无水硫酸铜0.1份、葡萄糖酸锰0.5份。
所述的复合增稠剂包括卡拉胶24份、瓜尔胶28份、***胶20份。
实施例3:
一种用于慢性胰腺炎患者的医用营养粉,包含如下重量份的组份:蛋白质类物质322份、脂肪类物质131份、碳水化合物523份、复合矿物质155份、复合维生素12份、牛磺酸0.96份、单双甘油脂肪酸酯1.2份、核苷酸0.2份、左旋肉碱0.15份、复合增稠剂22份、香草香精2.4份、阿斯巴甜0.66份;
所述的蛋白质类物质包含大豆分离蛋白96份、全脂奶粉96份、牛初乳4.8份、大豆低聚肽18份、水解乳清蛋白72份、鱼胶原蛋白肽18粉、海洋鱼低聚肽18份、L-精氨酸48份、L-谷氨酰胺48份。
所述的脂肪类物质包含紫苏油粉10份、椰子油粉45份、大豆油粉120份、橄榄油粉45份、中链甘油三酯粉6份。
所述的碳水化合物包含麦芽糊精324份、结晶果糖12份、低聚半乳糖12份、低聚异麦芽糖12份。
所述的复合维生素包括维生素A0.07份、维生素D30.05份、维生素E0.11份、维生素K10.001份、维生素B10.013份、维生素B20.013份、维生素B60.013份、维生素B120.0024份、L-抗坏血酸钠1.7份、D-泛酸钙0.04份、叶酸0.0024份、烟酰胺0.024份、氯化胆碱6份、D-生物素0.01份、肌醇4份。
所述的复合矿物质包括柠檬酸钙12份、L-乳酸钙12份、磷酸二氢钠12份、柠檬酸钠36份、葡萄糖酸镁28份、葡萄糖酸亚铁0.48份、葡萄糖酸锌0.6份、葡萄糖酸钾54份、***钠0.0014份、碘化钾0.001份、无水硫酸铜0.03份、葡萄糖酸锰0.15份。
所述的复合增稠剂包括卡拉胶7.2份、瓜尔胶8.4份、***胶6份。
实施例4:
根据实施例1中的一种用于慢性胰腺炎患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和去除无水硫酸铜后的复合矿物质;
预混料c:包括上述脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物、香草香精、阿斯巴甜、牛磺酸、左旋肉碱、核苷酸、复合维生素以及无水硫酸铜;
所述部分碳水化合物为一部分麦芽糊精、菊粉、低聚半乳糖、低聚异麦芽糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1:1:1;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为20r/min,最高/最低频率为50/5HZ,时间为50min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌50min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20r/min,搅拌5min;然后向预混料a、b中加入适量40%酒精粘合剂溶液500g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为10r/min,分散10r/min,加入部分酒精,喷加酒精的频率为2s/次,每次喷加酒精10g,间隔5s,加入后搅拌5min;其次设置搅拌速度为20r/min,分散20r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌10min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料、和预混料d的原辅料投入混料斗中进行预混,设置转速40r/min,时间为50min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40r/min,混合100min,得到成品。
实施例5:
结合实施例2中的一种用于慢性胰腺炎患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和去除无水硫酸铜后的复合矿物质;
预混料c:包括上述脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物、香草香精、阿斯巴甜、牛磺酸、左旋肉碱、核苷酸、复合维生素以及无水硫酸铜;
所述部分碳水化合物为一部分麦芽糊精、菊粉、低聚半乳糖、低聚异麦芽糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1.2:1.5:1.9;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为30r/min,最高/最低频率为50/5HZ,时间为80min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌80min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为30r/min,搅拌30min;然后向预混料a、b中加入适量40%酒精粘合剂溶液1200g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为30r/min,分散20r/min,加入部分酒精,喷加酒精的频率为8s/次,每次喷加酒精30g,间隔10s,加入后搅拌15min;其次设置搅拌速度为50r/min,分散50r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料、和预混料d的原辅料投入混料斗中进行预混,设置转速80r/min,时间为80min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速80r/min,混合150min,得到成品。
实施例6:
结合实施例3中的一种用于慢性胰腺炎患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和去除无水硫酸铜后的复合矿物质;
预混料c:包括上述脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物、香草香精、阿斯巴甜、牛磺酸、左旋肉碱、核苷酸、复合维生素以及无水硫酸铜;
所述部分碳水化合物为一部分麦芽糊精、菊粉、低聚半乳糖、低聚异麦芽糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1.5:1.8:1;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50-80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为25r/min,最高/最低频率为50/5HZ,时间为55min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌75min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为23r/min,搅拌15min;然后向预混料a、b中加入适量40%酒精粘合剂溶液1000g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为25r/min,分散10r/min,加入部分酒精,喷加酒精的频率为7s/次,每次喷加酒精15g,间隔9s,加入后搅拌13min;其次设置搅拌速度为45r/min,分散35r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌15min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料、和预混料d的原辅料投入混料斗中进行预混,设置转速80r/min,时间为55min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40r/min,混合125min,得到成品。
对于本领域技术人员而言,显然本发明不限于上述示范性实施例的细节,而且在不背离本发明的精神或基本特征的情况下,能够以其他的具体形式实现本发明。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本发明的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。
Claims (7)
1.一种用于慢性胰腺炎患者的医用营养粉,其特征在于:包含如下重量份的组份:蛋白质类物质135-1075份、脂肪类物质55-435份、碳水化合物218-1742份、复合矿物质65-516份、复合维生素5-40份、牛磺酸0.4-3.2份、单双甘油脂肪酸酯0.5-4份、核苷酸0.09-0.72份、左旋肉碱0.06-0.48份、复合增稠剂9-72份、香草香精1-8份、阿斯巴甜0.3-2.2份;所述的碳水化合物包含麦芽糊精135-1080份、结晶果糖5-40份、低聚半乳糖5-40份、低聚异麦芽糖5-40份。
2.根据权利要求1所述一种用于慢性胰腺炎患者的医用营养粉,其特征在于:所述的蛋白质包含大豆分离蛋白40-320份、全脂奶粉40-320份、牛初乳2-16份、大豆低聚肽7.5-60份、水解乳清蛋白30-240份、鱼胶原蛋白肽7.5-60粉、海洋鱼低聚肽7.5-60份、L-精氨酸20-160份、L-谷氨酰胺20-160份。
3.根据权利要求1所述一种用于慢性胰腺炎患者的医用营养粉,其特征在于:所述的脂肪包含紫苏油粉4.4-35份、椰子油粉19-152份、大豆油粉50-400份、橄榄油粉19-152份、中链甘油三酯粉2.5-20份。
4.根据权利要求1所述一种用于慢性胰腺炎患者的医用营养粉,其特征在于:所述的复合维生素包括维生素A0.03-0.24份、维生素D30.02-0.16份、维生素E0.045-0.36份、维生素K10.004-0.032份、维生素B10.005-0.04份、维生素B20.005-0.04份、维生素B60.005-0.04份、维生素B120.001-0.008份、L-抗坏血酸钠0.7-5.8份、D-泛酸钙0.015-0.12份、叶酸0.001-0.008份、烟酰胺0.01-0.08份、氯化胆碱2.5-20份、D-生物素0.0045-0.036份、肌醇1.65-13.2份。
5.根据权利要求1所述一种用于慢性胰腺炎患者的医用营养粉,其特征在于:所述的复合矿物质包括柠檬酸钙5-40份、L-乳酸钙5-40份、磷酸二氢钠5-40份、柠檬酸钠15-120份、葡萄糖酸镁12-92份、葡萄糖酸亚铁0.2-1.6份、葡萄糖酸锌0.25-2份、葡萄糖酸钾22.5-180份、***钠0.0006-0.0046份、碘化钾0.0004-0.0032份、无水硫酸铜0.0125-0.1份、葡萄糖酸锰0.0625-0.5份。
6.根据权利要求1所述一种用于慢性胰腺炎患者的医用营养粉,其特征在于:所述的复合增稠剂包括卡拉胶3-24份、瓜尔胶3.5-28份、***胶2.5-20份。
7.一种如权利要求1-6中任意一条所述的用于慢性胰腺炎患者的医用营养粉的制备方法,其特征在于:包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和去除无水硫酸铜后的复合矿物质;
预混料c:包括上述脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物、香草香精、阿斯巴甜、牛磺酸、左旋肉碱、核苷酸、复合维生素以及无水硫酸铜;
所述部分碳水化合物为一部分麦芽糊精、菊粉、低聚半乳糖、低聚异麦芽糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1-2:1-2:1-2;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50-80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为20-30r/min,最高/最低频率为50/5HZ,时间为50-80min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌50-80min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20-30r/min,搅拌5-30min;然后向预混料a、b中加入适量40%酒精粘合剂溶液500-1200g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为10-30r/min,分散10-20r/min,加入部分酒精,喷加酒精的频率为2-8s/次,每次喷加酒精10-30g,间隔5-10s,加入后搅拌5-15min;其次设置搅拌速度为20-50r/min,分散20-50r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌5-20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料、和预混料d的原辅料投入混料斗中进行预混,设置转速40-80r/min,时间为50-80min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40-80r/min,混合100-150min,得到成品。
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