CN111381064A - In-vitro diagnosis analyzer and method for improving use efficiency of sample rack thereof - Google Patents

In-vitro diagnosis analyzer and method for improving use efficiency of sample rack thereof Download PDF

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CN111381064A
CN111381064A CN201811628179.XA CN201811628179A CN111381064A CN 111381064 A CN111381064 A CN 111381064A CN 201811628179 A CN201811628179 A CN 201811628179A CN 111381064 A CN111381064 A CN 111381064A
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quality control
calibration
target
test
identity
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CN111381064B (en
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王起阳
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
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Abstract

According to the in-vitro diagnostic analyzer and the method for improving the use efficiency of the sample rack, the identity of the target quality control calibration rack is obtained by scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer; the identity mark of the target quality control calibration frame is associated with preset quality control setting and calibration setting; acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame; when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test. Therefore, one quality control calibration frame can be used for quality control test and calibration test, the multiplexing of the sample frame is realized, and the use efficiency of the sample frame is improved.

Description

In-vitro diagnosis analyzer and method for improving use efficiency of sample rack thereof
Technical Field
The invention relates to the field of medical instruments, in particular to an in-vitro diagnosis analyzer and a method for improving the use efficiency of a sample rack.
Background
For the in vitro diagnostic analyzer with larger test flux, sample introduction by adopting a sample rack is an indispensable ring. Within the industry, sample racks are typically identical in structure, but differ in color, barcode type. For example, a sample rack of a particular color can only be used for a particular type of test, as a conventional rack can only be used for a conventional test; the calibration rack is used for placing a calibration product, the bar code of the calibration rack usually starts with S, is used for distinguishing other types of racks and can only be used for calibration test; the quality control shelf is used for placing quality control products, and the bar code of the quality control shelf usually starts with C, is used for distinguishing other types of shelves and can only be used for quality control tests. For a rack-type sample introduction biochemical analyzer or an immunoassay analyzer, manufacturers can provide a conventional rack, a calibration rack, a quality control rack and the like to support users to perform different tests.
The quality control test is generally carried out by a clinical laboratory every day and is used for monitoring whether the quality of an instrument reagent system is out of control.
Since the reagent used in the biochemical analyzer or the immunoassay analyzer has a certain difference between different batches, the user generally performs a calibration test using a calibrator manufactured by the manufacturer after replacing the reagent batch to obtain parameters of the reagent batch.
It can be seen that the calibration racks purchased by the user are used only with a small probability, and are generally used only when the reagents are changed in batches. In most of the time, the calibration rack is in an idle state, which causes resource waste and increases the acquisition cost of users.
Disclosure of Invention
The invention mainly provides an in-vitro diagnosis analyzer and a method for improving the use efficiency of a sample rack thereof, and aims to improve the use efficiency of the sample rack.
One embodiment provides a method for improving the use efficiency of a sample rack, which comprises the following steps:
scanning a target quality control calibration frame entering the in-vitro diagnostic analyzer to obtain an identity of the target quality control calibration frame; the identity of the target quality control calibration frame is associated with preset quality control setting and calibration setting;
acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame;
when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test.
In one embodiment, the quality control setting comprises: a target sample position used for quality control test on the target quality control calibration frame and a test item to be executed by the target sample position; the calibration setup includes: the target quality control calibration frame is used for calibrating the target sample position of the test and the test item to be executed by the target sample position.
In one embodiment, before scanning a target quality control calibration rack entering an in vitro diagnostic analyzer to obtain an identification of the target quality control calibration rack, the method includes:
acquiring quality control product information or calibrator information in an input or scanning mode; the quality control product information at least comprises an identification of a quality control product and a quality control test item, and the calibration product information at least comprises an identification of a calibration product and a calibration test item;
receiving a selection signal for selecting the identity of the target quality control calibration frame or the input identity of the target quality control calibration frame, and determining the target quality control calibration frame where the quality control product or the calibration product is placed according to the selection signal or the identity;
receiving a selection signal for selecting a sample bit identifier or an input sample bit identifier, and determining a target sample bit for placing a quality control product or a calibration product according to the selection signal or the sample bit identifier;
correlating the identification of the quality control product, the quality control test item, the identity identification of the target quality control calibration frame and the sample position identification of the target sample position to obtain the quality control setting of the target quality control calibration frame; and associating the identifier of the calibration product, the calibration test item, the identity identifier of the target quality control calibration frame and the sample position identifier of the target sample position to obtain the calibration setting of the target quality control calibration frame.
In one embodiment, before scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer to obtain the identification of the target quality control calibration rack, the method further includes:
receiving an application for carrying out quality control test by using the target quality control calibration frame, associating the identity of the target quality control calibration frame with the quality control test application, and setting different quality control products at different target sample positions and corresponding to the associated quality control test items; receiving an application for carrying out calibration test by using the target quality control calibration frame, associating the identity of the target quality control calibration frame with the application of the calibration test, and setting different calibration products at different target sample positions and corresponding to associated calibration test items; the test type associated with the same identity is unique.
In one embodiment, the method further comprises:
and after the quality control test is finished, the association between the identity of the target quality control calibration frame and the quality control test application is released, and after the calibration test is finished, the association between the identity of the target quality control calibration frame and the calibration test application is released.
An embodiment provides an in vitro diagnostic analyzer comprising:
the scanning device is used for scanning the sample rack to obtain the identity of the sample rack; the sample rack comprises a quality control calibration rack, wherein the identity of the target quality control calibration rack is associated with preset quality control setting and calibration setting;
the testing device is used for testing the samples in the sample rack;
the processor is used for scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer through the scanning device to obtain the identity of the target quality control calibration rack; acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame; when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test.
In one embodiment, the quality control setting comprises: a target sample position used for quality control test on the target quality control calibration frame and a test item to be executed by the target sample position; the calibration setup includes: the target quality control calibration frame is used for calibrating the target sample position of the test and the test item to be executed by the target sample position.
In one embodiment, the system further comprises a human-computer interaction device for receiving input and output visual information of an operator; the processor is further configured to:
before the target quality control calibration frame entering the in-vitro diagnostic analyzer is scanned through the scanning device to obtain the identity of the target quality control calibration frame, quality control product information or calibrator information is obtained through a human-computer interaction device input mode or a scanning device scanning mode; the quality control product information at least comprises an identification of a quality control product and a quality control test item, and the calibration product information at least comprises an identification of a calibration product and a calibration test item;
receiving a selection signal for selecting the identity of the target quality control calibration rack or the input identity of the target quality control calibration rack through a human-computer interaction device, and determining a quality control product or the target quality control calibration rack in which the calibration product is placed according to the selection signal or the identity;
receiving a selection signal for selecting a sample bit identifier or an input sample bit identifier through a human-computer interaction device, and determining a target sample bit for placing a quality control product or a calibration product according to the selection signal or the sample bit identifier;
correlating the identification of the quality control product, the quality control test item, the identity identification of the target quality control calibration frame and the sample position identification of the target sample position to obtain the quality control setting of the target quality control calibration frame; and associating the identifier of the calibration product, the calibration test item, the identity identifier of the target quality control calibration frame and the sample position identifier of the target sample position to obtain the calibration setting of the target quality control calibration frame.
In one embodiment, the processor is further configured to:
scanning a target quality control calibration frame entering an in-vitro diagnostic analyzer by using a scanning device, receiving an application for performing a quality control test by using the target quality control calibration frame by using a human-computer interaction device before obtaining an identity of the target quality control calibration frame, associating the identity of the target quality control calibration frame with the quality control test application, and setting different quality control products at different target sample positions and corresponding to associated quality control test items; receiving an application for carrying out calibration test by using the target quality control calibration frame, associating the identity of the target quality control calibration frame with the application of the calibration test, and setting different calibration products at different target sample positions and corresponding to associated calibration test items; the test type associated with the same identity is unique.
In one embodiment, the processor is further configured to: and after the quality control test is finished, the association between the identity of the target quality control calibration frame and the quality control test application is released, and after the calibration test is finished, the association between the identity of the target quality control calibration frame and the calibration test application is released.
An embodiment provides a computer readable storage medium comprising a program executable by a processor to implement a method as described above.
According to the in-vitro diagnostic analyzer and the method for improving the use efficiency of the sample rack of the in-vitro diagnostic analyzer, the identity of the target quality control calibration rack is obtained by scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer; the identity mark of the target quality control calibration frame is associated with preset quality control setting and calibration setting; acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame; when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test. Therefore, one quality control calibration frame can be used for quality control test and calibration test, the multiplexing of the sample frame is realized, and the use efficiency of the sample frame is improved.
Drawings
Fig. 1 is a block diagram of an in vitro diagnostic analyzer according to an embodiment of the present invention;
FIG. 2 is a block diagram of an in vitro diagnostic analyzer according to an embodiment of the present invention;
FIG. 3 is a flowchart of a method for improving the efficiency of using a sample rack according to an embodiment of the present invention;
fig. 4 is a schematic diagram of a quality control calibration rack in the in-vitro diagnostic analyzer according to an embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments are numbered with like associated elements. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. Also, the various steps or actions in the method descriptions may be transposed or transposed in order, as will be apparent to one of ordinary skill in the art. Thus, the various sequences in the specification and drawings are for the purpose of describing certain embodiments only and are not intended to imply a required sequence unless otherwise indicated where such sequence must be followed.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
The terms used in this application are defined as follows:
sample preparation: body fluids to be analyzed, such as serum, plasma, urine, cerebrospinal fluid, amniotic fluid, and the like.
A sample rack: the carrier for placing the test tube is suitable for a rack-type sample injection in-vitro diagnostic analyzer.
Frame type sample introduction in vitro diagnosis analyzer: the test tube is dispatched to a sample adding port (a sample sucking position) of the analyzer through the sample rack, and the device for analyzing the sample can be a biochemical analyzer or an immunity analyzer.
Calibration products: a fluid that can be analyzed on an analyzer, and parameters of the batch of reagents are obtained from the analyzed data, and the parameters are used to calculate a test result of the patient sample when the patient sample is tested.
Quality control product: a fluid that can be analyzed on an analyzer monitors data obtained from the analysis whether the quality of the analyzer reagent system is out of control.
Sample position: the position on the sample rack where the sample is loaded.
In the embodiment of the invention, the sample rack is associated with the quality control setting and the calibration setting, and different settings are started according to different test applications of an operator, so that only one sample rack is needed for quality control test and calibration test, the number of the sample racks is saved, and the use efficiency of the sample racks is improved. The following examples are given for further illustration.
As shown in fig. 1, the in vitro diagnostic analyzer provided in this embodiment adopts a sample rack for sample injection, and is used for analyzing a sample to be detected, including: the system comprises a scanning device 10, a processor 20, a man-machine interaction device 30, a testing device 40 and a memory 50.
The scanning device 10 is used for scanning a sample rack entering the in-vitro diagnostic analyzer and test tubes carried by the sample rack to obtain the identity of the sample rack and the identity of the test tubes. The sample is usually placed in a test tube, which is not usually convenient for direct transport, and thus requires a sample rack for carrying, i.e. the transport of the sample is effected through the sample rack. Each sample rack has a unique identification, for example, a sample rack barcode is used as the identification of the sample rack. The identification of the test tube may be a sample barcode. The sample rack can carry one or more samples, and the embodiment is described by taking a plurality of samples as an example, that is, the sample rack has a plurality of sample positions, and the scanning device 10 can also obtain each sample position on the sample rack by scanning the sample rack. The sample rack is provided with a two-dimensional code, a bar code or a radio frequency label, and the like, and the identity and the sample position of the sample rack are obtained by scanning the sample rack, so that the sample rack and a sample thereof can be identified.
Referring to fig. 2, the testing device 40 is used for testing the samples in the sample rack a and outputting the testing results, for example, outputting the testing results to the processor 20 or storing the testing results in the memory 50. In the embodiment of the present invention, the testing device 40 may be used for performing immunoassay to detect antigen and antibody in a sample, and the corresponding in vitro diagnostic analyzer is an immunoassay analyzer; or biochemical analysis can be carried out to detect various substance components in the sample, and the corresponding in-vitro diagnosis analyzer is a biochemical analyzer. The components of the test apparatus 40 and the detection process vary depending on the purpose of analysis, and in the case of a biochemical analyzer, the test apparatus 40 generally includes a sampling mechanism (or referred to as a sample dispensing mechanism) 420, a reagent disk 430, a reaction disk 440, a measuring device 410, and a reagent collecting mechanism (or referred to as a reagent dispensing mechanism) 460. A test track 450 is generally provided at the front end (i.e., the side close to the operator) or the rear end (i.e., the back of the instrument) of the test device 40, a sample suction position 451 is designed on the test track 450, and the sampling mechanism 420 is used for sucking a sample to be tested from a sample rack a located at the sample suction position 451 and adding the sucked sample to a reaction vessel 441 placed on the reaction tray 440. The reagent collecting mechanism 460 serves to suck the reagent from the reagent tray 430 and add the reagent to the corresponding reaction container 441 so that the sample and the reagent react in the reaction container 441. Sampling mechanism 420 and reagent collection mechanism 460 may be different mechanisms or may be the same mechanism. The measuring device 410 measures the reacted sample to obtain a detection result. In other embodiments, the testing device 40 may also be a chemiluminescent instrument that also includes a magnetic separation disk, which will not be redundantly described.
The memory 50 is used to store various test data, analysis results, and/or programs.
The human-computer interaction device 30 serves as an interaction interface between the analyzer and an operator, and is used for receiving information input by the operator and outputting the information in an acoustic, optical or electrical mode. For example, a touch screen can be used, which can receive an instruction input by an operator and display visual information; a mouse, a keyboard, a trackball, a joystick, etc. may also be used as an input device of the human-computer interaction device 30 to receive instructions input by an operator, and a display may be used as a display device of the human-computer interaction device 30 to display visual information. The display displays the analysis result and/or prompt information obtained by the processor 20, or information such as the detection progress, to the operator in a visual manner.
In this embodiment, the sample rack includes a quality control calibration rack for quality control test and calibration test, a normal rack for normal test, and an emergency rack for emergency test. In the in-vitro diagnostic analyzer, the identification of the target quality control calibration rack is associated with preset quality control settings and calibration settings, for example, the memory 50 stores the quality control settings and calibration settings associated with the identification of the target quality control calibration rack.
The processor 20 is used for scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer through the scanning device 10 to obtain an identity of the target quality control calibration rack; acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame; when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test. Wherein, the quality control setting includes: a target sample position used for quality control test on the target quality control calibration frame and a quality control test item to be executed by the target sample position; the calibration setup includes: the target quality control calibration frame is used for calibrating the target sample position of the test and the quality control test item to be executed by the target sample position. For example, by presetting quality control setting and calibration setting, when an operator performs a quality control test, the operator only needs to put a test tube loaded with a corresponding quality control product on a target quality control calibration rack and send a quality control test application through the human-computer interaction device 30; similarly, when the calibration test is carried out, the test tube loaded with the corresponding calibrator is only required to be placed on the target quality control calibration frame, and the calibration test application is sent out through the human-computer interaction device 30, so that the multiplexing of the sample frame which can be used for both the quality control test and the calibration test is realized, and the use efficiency of the sample frame is improved. Since the quality control test is usually performed after starting the analyzer every day, and the calibration test is usually performed after replacing a new batch of reagents, which are staggered in time, the quality control and calibration test performed by using one sample holder according to the present invention is not confused.
Fig. 3 shows the whole process from the setting of the quality control setting and the calibration setting to the completion of the quality control test or the calibration test, that is, the processor 20 may also implement the method for improving the use efficiency of the sample rack provided by the embodiment of the present invention, and the specific steps are as follows:
step 1, acquiring quality control product information or calibrator information by a processor 20 on a quality control setting interface or a calibration setting interface; the quality control information at least comprises an identification of the quality control product and a quality control test item, and the calibrator information at least comprises an identification of the calibrator and a calibration test item. The quality control information and the calibrator information may be obtained by inputting through the human-computer interaction device 30, or by scanning through the scanning device 10. In the embodiment, the calibration test is taken as an example, and the operator uses the scanning device 10 to scan the barcode on the new batch of reagent to obtain the name, expiration date, batch, test item, master curve (curve of concentration and light emission value), quality control status, calibration status, etc. of the reagent. The new reagent is not calibrated, and the calibration state is 'calibration required'; the new reagent is not subjected to quality control test on the same day, and the quality control state is 'quality control required'. In the calibration setting interface, the operator scans the barcode on the calibrator corresponding to the reagent by using the scanning device 10 to obtain calibrator information, such as the identifier of the calibrator, the calibration test item, the main curve (the curve of the concentration and the light emission value), and the like. In other embodiments, the above operations may also be manually input by an operator through the human-computer interaction device 30, for example, a barcode of a reagent, a barcode of a calibration product, and so on, which are not described in detail.
And 2, the processor 20 receives a selection signal for selecting the identification of the target quality control calibration rack or the input identification of the target quality control calibration rack through the human-computer interaction device 30, and determines the quality control product or the target quality control calibration rack in which the calibration product is placed according to the selection signal or the identification. The calibration setting interface displayed by the display of the human-computer interaction device 30 is provided with an identification mark of the target quality control calibration frame for the operator to select, or is provided with an input frame for the operator to input the identification mark of the target quality control calibration frame. After the operator selects or inputs the identification of the target quality control calibration frame, the quality control calibration frame corresponding to the identification of the target quality control calibration frame is the target quality control calibration frame, and then the quality control calibration frame is adopted to load the calibration product.
And 3, the processor 20 receives a selection signal for selecting the sample bit identifier or the input sample bit identifier through the human-computer interaction device 30, and determines a target sample bit for placing the quality control product or the calibration product according to the selection signal or the sample bit identifier. The sample bit identifiers are usually numbers, taking 10 sample bits on the sample rack as an example, and usually 1-10 Arabic numbers to represent the sample bits.
Step 4, the processor 20 associates the identification of the quality control product, the quality control test item, the identification of the target quality control calibration rack and the sample bit identification of the target sample bit to obtain the quality control setting of the target quality control calibration rack and stores the quality control setting in the memory 50; and associating the identifier of the calibration product, the calibration test item, the identity identifier of the target quality control calibration frame and the sample bit identifier of the target sample bit to obtain the calibration setting of the target quality control calibration frame and storing the calibration setting in the memory 50. Since the calibration test is taken as an example in this embodiment, the test item of the calibration product, the identity of the target quality control calibration rack, and the sample bit identifier of the target sample bit are all set, and the processor 20 associates and stores them, that is, the calibration setting of the target quality control calibration rack is obtained, and the operator may repeat steps 1 to 4 to perform the quality control setting in the same manner, which is not repeated in this embodiment. The association is stored in the memory 50, so that the operator does not need to repeat the setting subsequently, in other words, the operator needs to complete the steps 1 to 8 when the operator uses the quality control calibration rack for the first time to perform the calibration test, and the operator only needs to complete the steps 5 to 8 when the operator uses the quality control calibration rack for the second time and subsequently to perform the calibration test, which is very convenient. The operator can also set the physical mark of the test item of the calibration product on each sample position of the target quality control calibration frame, and the sample frame can multiplex the quality control product and the calibration product, so the physical mark of the test item of the calibration product and the physical mark of the test item of the quality control product can be respectively set on two sides of the sample position. Of course, the operator can also modify, discard, create, etc. the calibration settings, quality control settings, etc. in the form of input instructions. In other embodiments, the calibration settings and quality control settings may be default and pre-stored in the memory 50.
And 5, in a quality control test application interface of the human-computer interaction device 30, the processor 20 receives an application for performing a quality control test by using the target quality control calibration frame through the human-computer interaction device 30, associates the identification of the target quality control calibration frame with the quality control test application, and sets different quality control products at different target sample positions and corresponding to the associated quality control test items. In the calibration test application interface of the human-computer interaction device 30, the processor 20 receives an application for performing a calibration test using the target quality control calibration rack through the human-computer interaction device 30, associates the identification of the target quality control calibration rack with the calibration test application, and sets different calibrators at different target sample positions and corresponding to the associated calibration test items. The identity identification of the same target quality control calibration frame is associated with a unique test type, namely the identity identification of the same target quality control calibration frame is not associated with a test application or is associated with a quality control test application or is associated with a calibration test application, and the two test applications cannot be associated simultaneously, so that fool-proofing is facilitated. In this embodiment, the operator puts the calibrator required by the calibration test into the test tube of the target sample position corresponding to the target quality control calibration rack, and places the target quality control calibration rack in the sample injection area. An operator sends an application for performing calibration test by using the target quality control calibration rack through the human-computer interaction device 30, the processor 20 displays the identity of the target quality control calibration rack and the associated calibrator identity, the calibration test item, the sample position identity of the target sample position and the like on a calibration test application interface through the human-computer interaction device 30 for the operator to check, and after receiving an instruction for starting the calibration test through the human-computer interaction device 30, the analyzer is started to sample.
And 6, scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer by the processor 20 through the scanning device 10 to obtain the identity of the target quality control calibration rack.
The existing quality control rack bar code is generally started with C, and the calibration rack bar code is generally started with S; in contrast, the control calibration rack of the present invention, which is illustrated in the schematic diagram of fig. 4, the bar code a1 may be in the form of a logo + number, such as SC, beginning with a number of digits (xxx). The circles in fig. 4 represent sample bits, and there are 10 sample bits in the figure, and 1-10 can be used as the sample bit identifiers for the 10 sample bits. Each sample position can correspond to a quality control product QC1 and a calibrator C1, the quality control calibration rack is more convenient to use in cooperation with a physical identifier, and an operator can clearly see what quality control product and what calibrator should be placed on the sample position.
Step 7, the processor 20 obtains the associated quality control test application or calibration test application according to the identity of the target quality control calibration frame, where the obtained application is the calibration test application in this embodiment.
Step 8, when the identity of the target quality control calibration frame is associated with a quality control test application, the processor 20 starts the associated quality control setting according to the identity of the target quality control calibration frame to perform a corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test. This embodiment is related to a calibration test application, so that after the target quality control calibration rack enters the sample suction position 451, the processor 20 sucks the calibrator through the sampling mechanism 420 and adds the sucked calibrator to the reaction vessel 441 placed on the reaction tray 440. The processor 20 sucks a reagent from the reagent tray 430 through the reagent collecting mechanism 460 and adds the reagent to the corresponding reaction container 441, so that the calibrator and the reagent react in the reaction container 441. The processor 20 measures the reacted sample by the measuring device 410 to obtain a detection result, and the processor 20 analyzes the detection result to obtain a result of the calibration test, thereby completing the calibration test.
After step 8, the processor 20 is further configured to release the association between the identity of the target quality control calibration rack and the quality control test application after the quality control test is finished, and release the association between the identity of the target quality control calibration rack and the calibration test application after the calibration test is finished, so as to perform another test application later.
In summary, the in vitro diagnostic analyzer and the method for improving the use efficiency of the sample rack thereof provided by the invention enable the quality control test and the calibration test to use the same sample rack, thereby realizing the multiplexing of the sample rack and improving the use efficiency of the sample rack.
Reference is made herein to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope hereof. For example, the various operational steps, as well as the components used to perform the operational steps, may be implemented in differing ways depending upon the particular application or consideration of any number of cost functions associated with operation of the system (e.g., one or more steps may be deleted, modified or incorporated into other steps).
Additionally, as will be appreciated by one skilled in the art, the principles herein may be reflected in a computer program product on a computer readable storage medium, which is pre-loaded with computer readable program code. Any tangible, non-transitory computer-readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROMs, DVDs, Blu Ray disks, etc.), flash memory, and/or the like. These computer program instructions may be loaded onto a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions which execute on the computer or other programmable data processing apparatus create means for implementing the functions specified. These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including means for implementing the function specified. The computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified.
While the principles herein have been illustrated in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components particularly adapted to specific environments and operative requirements may be employed without departing from the principles and scope of the present disclosure. The above modifications and other changes or modifications are intended to be included within the scope of this document.
The foregoing detailed description has been described with reference to various embodiments. However, one skilled in the art will recognize that various modifications and changes may be made without departing from the scope of the present disclosure. Accordingly, the disclosure is to be considered in an illustrative and not a restrictive sense, and all such modifications are intended to be included within the scope thereof. Also, advantages, other advantages, and solutions to problems have been described above with regard to various embodiments. However, the benefits, advantages, solutions to problems, and any element(s) that may cause any element(s) to occur or become more pronounced are not to be construed as a critical, required, or essential feature or element of any or all the claims. As used herein, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, system, article, or apparatus. Furthermore, the term "coupled," and any other variation thereof, as used herein, refers to a physical connection, an electrical connection, a magnetic connection, an optical connection, a communicative connection, a functional connection, and/or any other connection.
Those skilled in the art will recognize that many changes may be made to the details of the above-described embodiments without departing from the underlying principles of the invention. Accordingly, the scope of the invention should be determined from the following claims.

Claims (11)

1. A method for improving the use efficiency of a sample rack is characterized by comprising the following steps:
scanning a target quality control calibration frame entering the in-vitro diagnostic analyzer to obtain an identity of the target quality control calibration frame; the identity of the target quality control calibration frame is associated with preset quality control setting and calibration setting;
acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame;
when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test.
2. The method of claim 1, wherein the quality control settings comprise: a target sample position used for quality control test on the target quality control calibration frame and a test item to be executed by the target sample position; the calibration setup includes: the target quality control calibration frame is used for calibrating the target sample position of the test and the test item to be executed by the target sample position.
3. The method of claim 2, wherein scanning the target quality control calibration rack into the in vitro diagnostic analyzer to obtain the identification of the target quality control calibration rack comprises:
acquiring quality control product information or calibrator information in an input or scanning mode; the quality control product information at least comprises an identification of a quality control product and a quality control test item, and the calibration product information at least comprises an identification of a calibration product and a calibration test item;
receiving a selection signal for selecting the identity of the target quality control calibration frame or the input identity of the target quality control calibration frame, and determining the target quality control calibration frame where the quality control product or the calibration product is placed according to the selection signal or the identity;
receiving a selection signal for selecting a sample bit identifier or an input sample bit identifier, and determining a target sample bit for placing a quality control product or a calibration product according to the selection signal or the sample bit identifier;
correlating the identification of the quality control product, the quality control test item, the identity identification of the target quality control calibration frame and the sample position identification of the target sample position to obtain the quality control setting of the target quality control calibration frame; and associating the identifier of the calibration product, the calibration test item, the identity identifier of the target quality control calibration frame and the sample position identifier of the target sample position to obtain the calibration setting of the target quality control calibration frame.
4. The method of claim 3, wherein before scanning the target quality control calibration rack entering the in vitro diagnostic analyzer to obtain the identification of the target quality control calibration rack, the method further comprises:
receiving an application for carrying out quality control test by using the target quality control calibration frame, associating the identity of the target quality control calibration frame with the quality control test application, and setting different quality control products at different target sample positions and corresponding to the associated quality control test items; receiving an application for carrying out calibration test by using the target quality control calibration frame, associating the identity of the target quality control calibration frame with the application of the calibration test, and setting different calibration products at different target sample positions and corresponding to associated calibration test items; the test type associated with the same identity is unique.
5. The method of claim 4, further comprising:
and after the quality control test is finished, the association between the identity of the target quality control calibration frame and the quality control test application is released, and after the calibration test is finished, the association between the identity of the target quality control calibration frame and the calibration test application is released.
6. An in vitro diagnostic analyzer, comprising:
the scanning device is used for scanning the sample rack to obtain the identity of the sample rack; the sample rack comprises a quality control calibration rack, wherein the identity of the target quality control calibration rack is associated with preset quality control setting and calibration setting;
the testing device is used for testing the samples in the sample rack;
the processor is used for scanning the target quality control calibration rack entering the in-vitro diagnostic analyzer through the scanning device to obtain the identity of the target quality control calibration rack; acquiring a related quality control test application or a calibration test application according to the identity of the target quality control calibration frame; when a quality control test application is associated, starting the associated quality control setting according to the identity of the target quality control calibration frame to perform corresponding quality control test; and when the calibration test application is associated, starting the associated calibration setting according to the identity of the target quality control calibration frame to perform corresponding calibration test.
7. The in vitro diagnostic analyzer of claim 6, wherein the quality control settings comprise: a target sample position used for quality control test on the target quality control calibration frame and a test item to be executed by the target sample position; the calibration setup includes: the target quality control calibration frame is used for calibrating the target sample position of the test and the test item to be executed by the target sample position.
8. The in vitro diagnostic analyzer of claim 7, further comprising human-computer interaction means for receiving operator input and outputting visual information; the processor is further configured to:
before the target quality control calibration frame entering the in-vitro diagnostic analyzer is scanned through the scanning device to obtain the identity of the target quality control calibration frame, quality control product information or calibrator information is obtained through a human-computer interaction device input mode or a scanning device scanning mode; the quality control product information at least comprises an identification of a quality control product and a quality control test item, and the calibration product information at least comprises an identification of a calibration product and a calibration test item;
receiving a selection signal for selecting the identity of the target quality control calibration rack or the input identity of the target quality control calibration rack through a human-computer interaction device, and determining a quality control product or the target quality control calibration rack in which the calibration product is placed according to the selection signal or the identity;
receiving a selection signal for selecting a sample bit identifier or an input sample bit identifier through a human-computer interaction device, and determining a target sample bit for placing a quality control product or a calibration product according to the selection signal or the sample bit identifier;
correlating the identification of the quality control product, the quality control test item, the identity identification of the target quality control calibration frame and the sample position identification of the target sample position to obtain the quality control setting of the target quality control calibration frame; and associating the identifier of the calibration product, the calibration test item, the identity identifier of the target quality control calibration frame and the sample position identifier of the target sample position to obtain the calibration setting of the target quality control calibration frame.
9. The in vitro diagnostic analyzer of claim 8, wherein the processor is further configured to:
scanning a target quality control calibration frame entering an in-vitro diagnostic analyzer by using a scanning device, receiving an application for performing a quality control test by using the target quality control calibration frame by using a human-computer interaction device before obtaining an identity of the target quality control calibration frame, associating the identity of the target quality control calibration frame with the quality control test application, and setting different quality control products at different target sample positions and corresponding to associated quality control test items; receiving an application for carrying out calibration test by using the target quality control calibration frame, associating the identity of the target quality control calibration frame with the application of the calibration test, and setting different calibration products at different target sample positions and corresponding to associated calibration test items; the test type associated with the same identity is unique.
10. The in vitro diagnostic analyzer of claim 9, wherein the processor is further configured to: and after the quality control test is finished, the association between the identity of the target quality control calibration frame and the quality control test application is released, and after the calibration test is finished, the association between the identity of the target quality control calibration frame and the calibration test application is released.
11. A computer-readable storage medium, characterized by comprising a program executable by a processor to implement the method of any one of claims 1-5.
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