CN111330115B - Syringe and method for manufacturing same - Google Patents

Syringe and method for manufacturing same Download PDF

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Publication number
CN111330115B
CN111330115B CN201811552652.0A CN201811552652A CN111330115B CN 111330115 B CN111330115 B CN 111330115B CN 201811552652 A CN201811552652 A CN 201811552652A CN 111330115 B CN111330115 B CN 111330115B
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China
Prior art keywords
syringe
reservoir
fluid communication
pipe
manifold
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CN201811552652.0A
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CN111330115A (en
Inventor
李双春
贺小军
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Chongqing Beijia Medical Equipment Co ltd
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Chongqing Beijia Medical Equipment Co ltd
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Priority to CN201811552652.0A priority Critical patent/CN111330115B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A syringe is provided that includes a base; an injection cylinder fixed on the base and having an inner chamber in which a screw guide serving as a piston is disposed, wherein the injector further includes a lead screw, one end of which is screwed into the screw guide, and the other end of which is fixed to a knob for rotating the lead screw outside the injection cylinder, and a clockwork spring is further fixed on the lead screw.

Description

Syringe and method for manufacturing same
Technical Field
The present application relates to an injector, and in particular to an injector driven by a clockwork spring. The present application also relates to a method for manufacturing the syringe.
Background
In clinical applications, it is often desirable to perform long-term, uninterrupted injections of drugs. The existing non-manual injector for continuously injecting medicine often has the problem of unstable thrust, so that the injection amount of the medicine cannot be finely controlled.
Therefore, there is a need for an injector that can control the amount of medication injected without interruption and with precision and stability.
Disclosure of Invention
The object of the present application is to solve the above-mentioned drawbacks of the prior art or to at least reduce some of them to a certain extent.
To this end, the present application provides an injector driven by a clockwork spring. The injector can uninterruptedly inject medicine for a patient in 24 hours, and micro-control of medicine injection is realized. In addition, the medicine injector also has a quantitative injection function, so that a user can select continuous injection or manual quantitative injection according to actual requirements.
According to one aspect of the present application, there is provided a syringe comprising: a base; a syringe fixed to the base and having an internal chamber in which a screw guide serving as a piston is disposed. Wherein the syringe further comprises a lead screw, one end of which is screwed into the screw guide, and the other end of which is fixed to a knob for rotating the lead screw outside the syringe. In addition, a spring (3) is fixed on the screw rod (4).
According to one embodiment of the present application, the syringe further comprises: a manifold having an inlet end in fluid communication with the interior chamber of the syringe barrel; a first inlet tube having one end in fluid communication with a first outlet end of the manifold; the indwelling needle is communicated with the other end of the first liquid inlet pipe in a fluid mode; and a first check valve provided in the manifold to allow fluid to flow from the syringe to the indwelling needle.
According to an embodiment of the application, wherein a flow restriction pipe is arranged between the manifold and the first liquid inlet pipe.
According to an embodiment of the application, the syringe further comprises a reservoir in fluid communication with the inner chamber of the cartridge via a first connecting tube.
According to an embodiment of the present application, a second one-way valve is provided on the first connection tube to allow fluid to flow from the reservoir to the syringe.
According to an embodiment of the present application, the syringe further includes a bellows inner cylinder disposed inside the cartridge, one end of the bellows inner cylinder being fixed to a lower wall of the cartridge and the other end being fixed to a lower surface of the screw guide. Wherein the bellows inner barrel is in fluid communication with the manifold and the first connection tube.
According to an embodiment of the present application, wherein the screw guide includes an upper plate, a lower plate parallel to the upper plate, and a vertical plate connecting the upper plate to the lower plate, and wherein the upper plate and the vertical plate are provided in a hollow shape, and a screw is provided on the hollow of the upper plate.
According to an embodiment of the present application, wherein a groove extending in an axial direction is provided on an inner surface of a sidewall of the syringe, and a stopper portion is provided on a sidewall of the screw guide portion, the stopper portion being positioned in the groove to move in the axial direction and to prevent the screw guide portion from rotating relative to the syringe.
According to one embodiment of the present application, the injector further comprises a second connecting tube, one end of the second connecting tube being in fluid communication with the second outlet end of the manifold; and the other end of the second connecting pipe extends into the quantitative injection tube and is communicated with the cavity fluid of the quantitative injection tube.
According to an embodiment of the present application, the syringe further includes a third connection tube in fluid communication with the cavity of the quantitative syringe, and a second liquid inlet tube disposed between the third connection tube and the indwelling needle to allow the indwelling needle to be in fluid communication with the quantitative syringe.
According to an embodiment of the present application, the syringe further includes a switch disposed between the second outlet end and the second connecting pipe and between the third connecting pipe and the second liquid inlet pipe. The switch is switchable between:
-allowing the second outlet end to be in fluid communication with a second connecting pipe while preventing communication between the third connecting pipe and the second inlet pipe,
-allowing the third connecting pipe to be in fluid communication with the second inlet pipe while preventing communication between the second outlet end and the second connecting pipe; and
-simultaneously preventing communication between the third connecting pipe and the second inlet pipe, between the second outlet end and the second connecting pipe.
According to one embodiment of the present application, the syringe further comprises: the injection button is fixed on the end part of the quantitative injection tube opposite to the third connecting tube; a piston located within the dosing cartridge and secured to the base; and a first spring disposed at an outer circumference of the quantitative syringe and coupled to the injection button.
According to an embodiment of the present application, the first connection pipe, the manifold, the first liquid inlet pipe, the second connection pipe, the third connection pipe, the second liquid inlet pipe may be made of the same or different flexible materials, for example.
According to an embodiment of the present application, the syringe may further include: the liquid storage part pressing plate is arranged against the upper surface of the liquid storage part; at least two guide posts (e.g., four) extending vertically along opposite sides of the reservoir and through the reservoir platen; and the liquid storage part spring is arranged on the side part, opposite to the liquid storage part, of the liquid storage part pressing plate and abuts against the liquid storage part pressing plate along the guide upright post.
According to another aspect of the present application there is provided a method for manufacturing an injector driven by a clockwork spring, the method comprising: an injection cylinder is fixed on the base; a threaded guide serving as a plunger is placed in the interior cavity of the syringe barrel. Wherein the method may further comprise: screwing one end of a screw rod into the thread guide part; a knob for rotating the screw rod is fixed at the other end of the screw rod; and fixing a clockwork spring on the screw rod.
According to an embodiment of the present application, the method may further include: connecting a manifold to the syringe, wherein an inlet end of the manifold is in fluid communication with the interior chamber of the syringe; connecting a first inlet pipe in fluid communication on a first outlet end of the manifold; connecting an indwelling needle in fluid communication on an end of the first intake tube opposite the first outlet end of the manifold; a first one-way valve is provided on the manifold to allow fluid flow from the syringe to the retaining needle.
According to an embodiment of the present application, the method may further comprise providing a flow restriction pipe between the manifold and the first liquid inlet pipe.
According to an embodiment of the present application, the method may further comprise providing a reservoir in fluid communication with the inner chamber of the cartridge via a first connection tube.
According to an embodiment of the present application, the method may further comprise providing a second one-way valve on the first connection tube to allow fluid to flow from the reservoir to the syringe.
According to one embodiment of the present application, the method can further comprise disposing a bellows inner barrel within the syringe barrel. One end of the bellows inner cylinder is fixed to a lower wall of the syringe barrel, the other end is fixed to a lower surface of the screw guide, and the bellows inner cylinder is in fluid communication with the manifold and the second connecting pipe.
According to an embodiment of the present application, wherein the thread guide may include an upper plate, a lower plate parallel to the upper plate, and a riser connecting the upper plate to the lower plate. The upper plate and the vertical plate are hollow, a limiting part is arranged on the side wall of the thread guide part, and threads are arranged on the hollow part of the upper plate.
According to an embodiment of the present application, the method may further comprise molding a groove extending in an axial direction on an inner surface of a sidewall of the syringe, positioning the stopper in the groove to move in the axial direction and prevent the stopper from rotating relative to the syringe.
According to an embodiment of the present application, the method may further comprise connecting a second connecting tube in fluid communication at a second outlet end of the manifold; and extending one end of the second connecting pipe opposite to the second outlet end of the manifold into a quantitative injection cylinder, wherein the second connecting pipe is communicated with the cavity of the quantitative injection cylinder in a fluid manner.
According to an embodiment of the present application, the method may further include connecting a third connection tube in fluid communication with a lower end of the cavity of the quantitative syringe; and a second liquid inlet pipe is arranged between the third connecting pipe and the remaining needle so as to allow the remaining needle to be in fluid communication with the quantitative injection cylinder.
According to an embodiment of the present application, the method may further include providing a switch between the second outlet end and a second connection pipe and between the third connection pipe and the second liquid inlet pipe. The switch is capable of switching between:
-allowing the second outlet end to be in fluid communication with a second connection pipe, while preventing communication between the third connection pipe and the second inlet pipe,
-allowing said third connecting pipe to be in fluid communication with said second inlet pipe, while preventing communication between said second outlet end and second connecting pipe; and
-simultaneously preventing communication between the third connecting pipe and the second inlet pipe, between the second outlet end and the second connecting pipe.
According to an embodiment of the present application, the method may further comprise fixing an injection button on an end of the dosing cartridge opposite to the third connection tube; securing a piston within the dosing cartridge to the base; and providing a first spring at an outer circumference of the dosing cylinder and coupling the first spring to the injection button.
According to one embodiment of the present application, the method may further comprise disposing a reservoir platen against an upper surface of the reservoir; providing at least two (e.g., four) guide posts extending vertically along opposite sides of the reservoir and through the reservoir platen; and a liquid storage part spring is arranged on the side part of the liquid storage part pressing plate opposite to the liquid storage part and abutted against the liquid storage part pressing plate along the guide upright post.
Drawings
The principles of the present inventive concept are explained below by describing exemplary embodiments of the present application in conjunction with the accompanying drawings. It is to be understood that the drawings are intended to illustrate exemplary embodiments of the application and not to limit the same. The accompanying drawings are included to provide a further understanding of the inventive concepts of the application, and are incorporated in and constitute a part of this specification. Like reference numerals in the drawings denote like features. In the drawings:
FIG. 1 shows a front view of a syringe according to an embodiment of the present application;
FIG. 2 shows a schematic view of an injector according to an embodiment of the present application with the syringe in an unfilled state;
FIG. 3 shows a schematic view of an injector according to embodiments of the present application with the syringe barrel in a filling state; and
fig. 4 shows a schematic view of a guide in a syringe according to an embodiment of the present application.
Detailed Description
For a better understanding of the present application, various aspects of the present application will be described in more detail below with reference to the accompanying drawings. It should be understood that the detailed description is merely illustrative of exemplary embodiments of the present application and does not limit the scope of the present application in any way.
The terminology used herein is for the purpose of describing particular example embodiments and is not intended to be limiting. The terms "comprises," "comprising," "has," "having," "includes" and/or "including," when used in this specification, specify the presence of stated features, integers, elements, components, and/or groups thereof, but do not preclude the presence or addition of one or more other features, integers, elements, components, and/or groups thereof.
It should be noted that in the present specification, expressions such as first, second, etc. are used only for distinguishing one feature from another feature, and do not indicate any limitation on the features. Thus, the first connecting tube, the first liquid inlet tube, discussed below may also be referred to as the second connecting tube, the second liquid inlet tube, without departing from the teachings of the present application.
This description is made with reference to schematic illustrations of exemplary embodiments. The exemplary embodiments disclosed herein should not be construed as limited to the particular shapes and dimensions shown, but are to include various equivalent structures capable of performing the same function, as well as deviations in shapes and dimensions that result, for example, from manufacturing. The locations shown in the drawings are schematic in nature and are not intended to limit the specific locations of the various components.
Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. Terms such as those defined in commonly used dictionaries should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
Various aspects of the present application are described in more detail below with reference to the figures.
Fig. 1 shows a front view of a syringe 100 according to an embodiment of the present application. Syringe 100 is integrally supported by base 16. The base 16 may be integrally formed by injection molding, hot press molding, or the like, for example. The base 16 is made of a rigid material such as, but not limited to, metal, phenolic, polyurethane plastic, epoxy plastic, unsaturated polyester plastic, furan plastic, silicone resin, acryl resin, or the like.
Syringe 100 may include a barrel 8 secured to a base 16. A threaded guide 6 may be provided in the barrel 8. The guide 6 may function as a piston. The threaded end of the screw rod 4 can be screwed to the upper end of the guide part 6. A knob 1 can be fixed to the other end of the spindle 4. In addition, a spring 3 is fixed on the screw rod 4, and the spring 3 is positioned between the injection cylinder 8 and the knob 1 on the screw rod 4. When the spring is used, the spring 3 and the screw rod 4 are driven to rotate by screwing the knob 1, so that the guide part 6 is driven to move upwards. The lower end of the guide 6 is in sealing engagement with the interior chamber of the barrel 8 so that when the guide 6 is moved upwardly a negative pressure is created in the interior chamber of the barrel 8 to allow fluid to be drawn into the barrel 8.
In another embodiment, a bellows inner cylinder 7 may be further provided in the inner chamber of the syringe 8, one end of which is fixed to the lower wall of the syringe 8 and the other end of which is fixed to (e.g., adhered to) the lower surface of the guide 6, thereby moving the bellows inner cylinder 7 up and down when the guide 6 moves up and down.
Referring to fig. 1, the syringe 100 may further include a reservoir 13 in fluid communication with the interior chamber of the syringe 8 or the bellows inner barrel 7 via a connecting tube 11 to supply fluid through the connecting tube 11 into the interior chamber of the syringe 8 or the bellows inner barrel 7. A check valve 10 is provided in the connection tube 11, and the check valve 10 allows the fluid to flow from the reservoir 13 to the syringe 8 without flowing back from the syringe 8 to the reservoir 13. The one-way valve may be any type of one-way valve known in the art, for example, and may also be a membrane one-way valve as described in CN 107029317 a.
Fig. 2 shows a schematic view of an injector 100 according to an embodiment of the present application with the syringe 8 in an unfilled state and fig. 3 shows a schematic view of the injector 100 according to an embodiment of the present application with the syringe 8 in a filled state.
As shown in fig. 1 to 3, the lower end of the injection tube 8 is further provided with a liquid outlet. When injection is performed, fluid flows through the fluid outlet via the manifold 12, the fluid inlet tube 26 and into the indwelling needle. A one-way valve 9 may be provided in the manifold 12 to allow fluid flow from the syringe 8 to the retaining needle 23. The check valve 9 may have the same configuration as the check valve 10 and will not be described in detail herein. For precise micro-control, a capillary flow restriction 5 may also be provided between the manifold 12 and the inlet pipe 26. The capillary flow-limiting tube 5 may be, for example, a flow-limiting glass tube.
The reservoir 13 is arranged adjacent to the barrel 8 in the base 16. A platen 19 is provided above the reservoir 13. The platen 19 is movable up and down along guide posts 30 located at the periphery of the reservoir 13. As shown in fig. 1, the guide posts 30 extend upwardly through the platen 19 to the upper wall of the base. A reservoir spring 21 is provided over the length of the guide post 30 above the platen 19. With this arrangement, when the reservoir 13 is filled with fluid through the inlet port 14, the reservoir causes the pressure plate to move upward along the guide post 30, thereby compressing the spring and accumulating force in the spring. After the liquid storage part 13 is filled with the fluid, the liquid inlet is sealed by the sealing cover, so that the fluid in the liquid storage part 13 is in a compressed state, and is convenient to discharge from the liquid storage part 13 in use.
In another embodiment, the syringe 100 also functions as a quantitative syringe. In this embodiment, injector 100 may also include a dosing barrel 24 located on pressure plate 19 and secured to base 16. The other outlet end of the manifold 12 is in fluid communication with the cavity of the dosing cartridge 24. Alternatively, an intermediate connecting tube 15 can also be provided between the manifold 12 and the dosing cylinder 24.
The fluid in the quantitative syringe 24 can flow into the retaining needle 23 through another liquid inlet tube 22. Alternatively, a further intermediate connecting tube 17 can also be provided between the metering syringe 24 and the inlet tube 22.
In the embodiment having the function of the quantitative syringe, the communication between the quantitative syringe 24 and the indwelling needle 23, and between the quantitative syringe 24 and the syringe 8, are controlled by the selector switch 18. As shown in fig. 1, the switch 18 may be disposed between the second outlet end 122 of the manifold 12 and the connecting tube 15 and between the connecting tube 17 and the inlet tube 22. The changeover switch 18 can be switched between: a) allowing the second outlet end 122 to be in fluid communication with the connecting pipe 15 while preventing communication between the connecting pipe 17 and the inlet pipe 22; b) allowing the connection pipe 17 to be in fluid communication with the inlet pipe 22 while preventing communication between the second outlet end 122 and the connection pipe 15; and c) simultaneously preventing communication between the connection pipe 17 and the second inlet pipe 22 and between the second outlet end 122 and the connection pipe 15.
When the user wishes to use the dosing function, he can press the injection button 25 fixed on the end of the dosing cylinder 24 opposite to the connection tube 17. A spring 20 is coupled to the lower end of the injection button 25. The spring 20 surrounds the outer wall of the dosing cylinder 24 and is fixed at its other end to the base 16. A plunger (not shown) is provided in the cartridge 24, one end of which is fixed to the base 16, so that when the button 25 is pressed, the dosing cartridge 24 and the spring 22 move downwards, so that a negative pressure is produced between the plunger and the dosing cartridge 24. When the switch is in state a), fluid is drawn into the dosing cartridge 24. When an injection is required, the selector switch is toggled to state b), at which time the force accumulated in the spring 22 moves the dosing cylinder 24 upwards, causing fluid to flow into the indwelling needle 23.
In another exemplary embodiment, as shown in fig. 4, the screw guide 6 may include an upper plate 6a, a lower plate 6b parallel to the upper plate, and a riser plate 6c connecting the upper plate to the lower plate. The upper plate 6a and the riser 6c may be provided in a hollow shape, for example, and a screw thread is provided on the hollow portion of the upper plate 6 a. In addition, a groove extending in the axial direction may be provided on the inner surface of the side wall of the syringe 8, and a stopper may be provided on the side wall of the screw guide 6. A stop is positioned in the recess to move in the axial direction and prevent the screw guide 6 from rotating relative to the syringe 8.
It should be noted that the connecting tubes and the liquid inlet tube may be made of any suitable flexible material. The syringe 8 and the dosing syringe 24 can be provided in different shapes, sizes and proportions according to the actual needs and are not limited to what is shown in the figures of the present application.
In addition, the syringe can be used in other fields besides medical injection. Such as, but not limited to, for providing biochemical catalysts, and the like.
The operation of the syringe 100 will now be described with reference to the above features.
Liquid storage part 13 liquid feeding
A certain amount of fluid is injected into the liquid storage part 13 through the liquid inlet 14 by using a disposable needle tube, the liquid storage part is in fluid communication with the injection tube 8 through the connecting tube 11, the one-way valve 10 and the injection tube 8, and the one-way valve 10 controls the fluid to flow from the liquid storage part 13 to the injection tube 8 only but not to flow reversely.
8 liquid additions of injection tube:
anticlockwise screw the knob 1, knob 1 drives clockwork spring 3 and lead screw 4 and rotates, drive 6 rebound of guide part through lead screw 4, thereby drive the bellows inner tube 7 that links to each other with it and expand, stock solution portion spring 21 can compress stock solution portion 13 through clamp plate 19 this moment, the liquid that receives the pressure effect can flow into bellows inner tube 7 from stock solution portion 13 through the intercommunication pipeline, explain when knob 1 is twisted motionless that the guide part has moved extreme position, the required injection liquid has been added enough for 24 hours in the injection tube 8 this moment, then the release.
Basic injection:
because the knob 1 drives the clockwork spring 3 to accumulate force when the injection tube 8 is filled with liquid, under the condition that the knob 1 is not stressed, the elastic force stored by the clockwork spring 3 is automatically released to drive the screw rod 4 to rotate clockwise, and then the guide part 6 is driven to compress the bellows inner tube 7, so that the fluid in the bellows inner tube 7 flows through the check valve 9 (the check valve 9 controls the liquid to only flow out of the injection tube 8 and prevent backflow), the connecting tube 12 flows to the flow-limiting tube 5, then flows into the remaining needle 23 through the liquid inlet tube 26, and is injected into a human body through the remaining needle 23.
Quantitative injection:
when a quantitative injection of a medicine is required in a short time, the quantitative injection button 25 is pressed, the quantitative injection button 25 drives the outer wall of the quantitative injection syringe 24 to move downwards (the inner piston is fixed), the syringe and the piston are separated to generate negative pressure, liquid in the injection syringe 8 flows into the quantitative injection syringe 24 through the check valve 9, the connecting pipe 12 and the switch 18 under the action of pressure (the switch 18 has three states of a), the connecting pipe 12 is opened, the connecting pipe 17 is closed, the connecting pipes 12 and 17 are closed simultaneously, c) the connecting pipe 12 is closed and the connecting pipe 17 is opened), the quantitative injection switch 18 is shifted to the state of c) after the quantitative injection button 25 is pressed in place, the quantitative injection button 25 is released, and at the moment, the internal liquid is injected into a human body through the connecting pipe 17, the connecting pipe 22 and the remaining needle 23 under the action of the spring 20. If the single injection quantity can not meet the requirement, multiple quantitative injections are needed, and the operation is repeated.
The present application also relates to methods for manufacturing syringes according to embodiments of the present application. In this method, the base 16 may be obtained by molding or the like, and then the syringe 8 and the retaining needle 23 are fixed to the base 16. After the threaded guide 6 is placed inside the syringe 8, one end of the lead screw 4 is screwed into the threaded guide 6, and the knob 1 is fixed on the other end of the lead screw 4. The spring 3 is fixed to the lead screw 4 before the knob 1 is fixed, and thus the spring 3 is positioned between the syringe and the knob 1 on the lead screw 4.
The inner chamber of the syringe 8 is connected in fluid communication to an inlet tube 26 via a connecting manifold 12, which in turn is connected in fluid communication to an indwelling needle 23. A one-way valve 9 is provided on the manifold 12 to allow fluid to flow from the syringe 8 to the retaining needle 23. A flow restriction tube 5 may also be provided between the manifold 12 and the first inlet tube 26 to achieve accurate microfluidic control.
In another embodiment of the method, a bellows inner barrel 7 can also be provided within the syringe 8. One end of the bellows inner cylinder 7 is fixed to the lower wall of the syringe 8, the other end is fixed to the lower surface of the screw guide 6, and the bellows inner cylinder 7 is in fluid communication with the manifold 12 and the connection pipe 15.
The method may further comprise forming a recess extending in the axial direction in the inner surface of the side wall of the syringe 8 and positioning said stopper in the recess such that the stopper is movable in the axial direction but not rotatable relative to said syringe 8.
The method further includes securing a reservoir 13 to the base 16, the reservoir being in fluid communication with the interior chamber of the syringe 8 via the connecting tube 11. A one-way valve 10 is provided on the connecting tube 11 to allow fluid to flow from the reservoir 13 to the barrel 8.
In a further embodiment of the method, a connecting tube 15 may also be connected in fluid communication at the outlet end 122 of the manifold 12, and an end of the connecting tube 15 opposite to the outlet end 122 of the manifold 12 extends into the dosing cylinder 24, such that the connecting tube 15 is in fluid communication with the cavity of the dosing cylinder 24. The lower end of the cavity of the quantitative syringe 24 is connected to the third connection pipe 17 in fluid communication, and the second inlet pipe 22 is provided between the third connection pipe 17 and the indwelling needle 23 to allow the indwelling needle to be in fluid communication with the quantitative syringe 24.
In order to control the opening and closing of the fixed-quantity injection, a changeover switch 18 is provided between the outlet end 122 and the connecting pipe 15 and between the connecting pipe 17 and the liquid inlet pipe 22, so that the changeover switch 18 can be switched between:
quantitative injection cylinder filling stage: allowing the outlet end 122 to be in fluid communication with the connecting pipe 15, while preventing communication between the connecting pipe 17 and the inlet pipe 22,
a quantitative injection stage: allowing the connection pipe 17 to be in fluid communication with the inlet pipe 22, while preventing communication between the outlet end 122 and the connection pipe 15; and
and (3) closing stage: while preventing communication between the connecting pipe 17 and the liquid inlet pipe 22 and between the outlet end 122 and the connecting pipe 15.
The method further comprises fixing an injection button 25 on the end of the dosing cylinder 24 opposite the connecting tube 17 and fixing a piston located inside the dosing cylinder 24 to the base 16, and arranging a spring 20 at the periphery of the dosing cylinder 24 and coupling the spring 20 to the injection button 25. A reservoir pressure plate 19 is provided on the reservoir 13 against the upper surface of the reservoir 13. Guide posts 30 are provided along opposite sides of the reservoir 13 such that the guide posts 30 extend vertically through the reservoir platen 19. On the side of the reservoir platen 19 opposite the reservoir 13, a reservoir spring 21 is provided along the guide post 30 against the reservoir platen 19.
Exemplary embodiments of the present application are described above with reference to the accompanying drawings. It will be understood by those skilled in the art that the present application can be modified as necessary for use in other fields of biological, chemical, and industrial production, in addition to drug injection. The above embodiments are merely examples provided for illustrative purposes, and are not intended to limit the scope of the present application. The scope of the present application is to be given the full breadth of the appended claims and any and all equivalents thereof, including any combination of features thereof. Any modifications, equivalents and the like which come within the teachings of this application and the scope of the claims should be considered to be within the scope of this application.

Claims (24)

1. A syringe, comprising:
a base (16);
a syringe (8) fixed on the base (16) and having an inner chamber in which a screw guide (6) serving as a piston is arranged,
wherein the injector further comprises a screw (4), one end of the screw (4) is screwed into the screw guide (6), and the other end of the screw (4) is fixed to a knob (1) for rotating the screw outside the syringe (8),
wherein a clockwork spring (3) is also fixed on the screw rod (4);
a manifold (12) having an inlet end in fluid communication with the inner chamber of the syringe (8);
a first inlet pipe (26) having one end in fluid communication with a first outlet end of the manifold (12);
a remaining needle (23) in fluid communication with the other end of the first fluid inlet tube (26);
a first one-way valve (9) provided in the manifold (12) to allow fluid to flow from the syringe (8) to the indwelling needle (23);
a flow restriction pipe (5) arranged between the manifold (12) and the first liquid inlet pipe (26); and
a bellows inner cylinder (7) disposed within the syringe (8), one end of the bellows inner cylinder (7) being fixed to a lower wall of the syringe (8) and the other end being fixed to a lower surface of the screw guide (6), wherein the bellows inner cylinder (7) is in fluid communication with the manifold (12).
2. Syringe according to claim 1, further comprising a reservoir (13), the reservoir (13) being in fluid communication with the inner chamber of the barrel (8) via a first connecting tube (11).
3. The injector of claim 2,
a second one-way valve (10) is arranged on the first connecting tube (11), the second one-way valve (10) allowing fluid to flow from the reservoir (13) to the cartridge.
4. The syringe as set forth in claim 3,
wherein the bellows inner cylinder (7) is in fluid communication with the first connection tube (11).
5. The syringe of claim 1,
the screw guide (6) comprises an upper plate (6a), a lower plate (6b) parallel to the upper plate, and a riser plate (6c) connecting the upper plate to the lower plate,
wherein the upper plate and the vertical plate are provided in a hollow shape, and a thread is provided on the hollow portion of the upper plate.
6. The injector of claim 5,
a groove extending in the axial direction is provided on the inner surface of the side wall of the injection cylinder (8), an
A stop is provided at the side wall of the screw guide (6) which is positioned in the recess to move in the axial direction and prevent the screw guide (6) from rotating relative to the syringe (8).
7. The injector of claim 3, further comprising:
a second connecting tube (15), one end of the second connecting tube (15) being in fluid communication with a second outlet end (122) of the manifold (12);
and the other end of the second connecting pipe (15) extends into the quantitative injection cylinder (24) and is communicated with the cavity of the quantitative injection cylinder (24) in a fluid mode.
8. The injector of claim 7, further comprising:
a third connecting pipe (17) which is communicated with the cavity of the quantitative injection cylinder (24) in a fluid mode; and
a second fluid inlet tube (22) disposed between the third connecting tube (17) and the indwelling needle (23) to allow the indwelling needle to be in fluid communication with the quantitative syringe (24).
9. The injector of claim 8, further comprising:
a diverter switch (18) disposed between the second outlet end (122) and the second connecting pipe (15) and between the third connecting pipe (17) and the second inlet pipe (22),
wherein the switch is switchable between:
allowing the second outlet end (122) to be in fluid communication with a second connection pipe (15) while preventing communication between the third connection pipe (17) and the second inlet pipe (22),
-allowing the third connection pipe (17) to be in fluid communication with the second inlet pipe (22), while preventing communication between the second outlet end (122) and the second connection pipe (15); and
and simultaneously prevents the communication between the third connecting pipe (17) and the second liquid inlet pipe (22) and between the second outlet end (122) and the second connecting pipe (15).
10. The syringe of claim 9, further comprising:
an injection button (25) fixed to the end of the quantitative injection cylinder (24) opposite to the third connection tube (17),
a piston located inside the dosing cartridge (24) and fixed to the base (16),
a first spring (20) arranged at the periphery of the dosing cylinder (24) and coupled to the injection button (25).
11. The injector of claim 2,
the first connecting pipe (11), the manifold (12) and the first liquid inlet pipe (26) are made of flexible materials.
12. The injector of claim 8,
the second connecting pipe (15), the third connecting pipe (17) and the second liquid inlet pipe (22) are made of flexible materials.
13. The syringe of claim 10, further comprising:
a liquid reservoir pressure plate (19) disposed against an upper surface of the liquid reservoir (13);
at least two guide posts (30) extending vertically along opposite sides of the reservoir (13) and through the reservoir platen (19); and
a reservoir spring (21) disposed along the guide post on a side of the reservoir platen (19) opposite the reservoir (13) against the reservoir platen (19).
14. A method for manufacturing an injector driven by a clockwork spring, comprising:
an injection cylinder (8) is fixed on the base (16);
placing a threaded guide (6) acting as a piston in the internal cavity of the syringe (8);
characterized in that the method further comprises:
screwing one end of a screw rod (4) into the thread guide part (6);
a knob (1) for rotating the screw rod is fixed at the other end of the screw rod (4); and
a clockwork spring (3) is fixed on the screw rod (4);
-connecting a manifold (12) to the syringe (8), wherein the inlet end of the manifold is in fluid communication with the inner chamber of the syringe (8);
connecting a first intake pipe (26) in fluid communication over a first outlet end of the manifold (12);
-connecting in fluid communication an indwelling needle (23) on the end of the first intake tube (26) opposite the first outlet end of the manifold (12);
-providing a first one-way valve (9) on the manifold (12) to allow fluid flow from the syringe (8) to the retention needle (23);
-providing a flow restriction pipe (5) between the manifold (12) and the first inlet pipe (26);
an inner bellows cylinder (7) is provided within the syringe (8), wherein one end of the inner bellows cylinder (7) is fixed to a lower wall of the syringe (8) and the other end is fixed to a lower surface of the screw guide (6), and the inner bellows cylinder (7) is in fluid communication with the manifold (12).
15. The method of claim 14, further comprising:
a reservoir (13) is provided, the reservoir (13) being in fluid communication with the inner chamber of the syringe (8) via a first connecting tube (11).
16. The method of claim 15, further comprising:
a second one-way valve (10) is arranged on the first connecting tube (11) to allow fluid to flow from the reservoir (13) to the cartridge.
17. The method of claim 16, further comprising:
a second connecting tube (15) is provided in the syringe, the bellows inner cylinder (7) being in fluid communication with the second connecting tube (15).
18. The method of claim 14, wherein,
the screw guide (6) comprises an upper plate (6a), a lower plate (6b) parallel to the upper plate, and a riser plate (6c) connecting the upper plate to the lower plate,
the upper plate and the vertical plate are hollow, a limiting part is arranged on the side wall of the thread guide part (6), and threads are arranged on the hollow part of the upper plate.
19. The method of claim 18, further comprising:
a groove extending along the axial direction is formed on the inner surface of the side wall of the injection cylinder (8),
positioning the stopper in the recess to move in an axial direction and prevent rotation of the stopper relative to the syringe (8).
20. The method of claim 16, further comprising:
-connecting a second connecting tube (15) in fluid communication at a second outlet end (122) of the manifold (12);
-extending an end of the second connecting tube (15) opposite to the second outlet end (122) of the manifold (12) into a dosing cartridge (24), wherein the second connecting tube (15) is in fluid communication with the cavity of the dosing cartridge (24).
21. The method of claim 20, further comprising:
a third connecting pipe (17) is connected to the lower end of the cavity of the quantitative injection cylinder (24) in a fluid communication manner; and
a second fluid inlet tube (22) is provided between the third connecting tube (17) and the indwelling needle (23) to allow the indwelling needle to be in fluid communication with the dosing cylinder (24).
22. The method of claim 21, further comprising:
a change-over switch (18) is arranged between the second outlet end (122) and the second connecting pipe (15) and between the third connecting pipe (17) and the second liquid inlet pipe (22),
wherein the switch is switchable between:
allowing the second outlet end (122) to be in fluid communication with a second connection pipe (15) while preventing communication between the third connection pipe (17) and the second inlet pipe (22),
-allowing the third connection pipe (17) to be in fluid communication with the second inlet pipe (22), while preventing communication between the second outlet end (122) and the second connection pipe (15); and
and simultaneously prevents the communication between the third connecting pipe (17) and the second liquid inlet pipe (22) and between the second outlet end (122) and the second connecting pipe (15).
23. The method of claim 22, further comprising:
an injection button (25) is fixed on the end of the quantitative injection cylinder (24) opposite to the third connecting pipe (17),
securing a plunger located within the dosing cartridge (24) to the base (16), an
-arranging a first spring (20) at the periphery of the dosing cylinder (24) and coupling the first spring (20) to the injection button (25).
24. The method of claim 23, further comprising:
a liquid storage part pressure plate (19) is arranged against the upper surface of the liquid storage part (13);
providing at least two guide posts (30), the guide posts (30) extending vertically along opposite sides of the reservoir (13) and through the reservoir platen (19); and
a reservoir spring is provided along the guide post against the reservoir platen (19) on a side of the reservoir platen (19) opposite the reservoir (13).
CN201811552652.0A 2018-12-18 2018-12-18 Syringe and method for manufacturing same Active CN111330115B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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CN111330115B true CN111330115B (en) 2022-06-24

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH294905A (en) * 1951-03-19 1953-11-30 Scherer Corp R P Jet injection syringe.
CN104703640A (en) * 2012-10-04 2015-06-10 欧文蒙福德有限公司 Pen injector apparatus
CN106267459A (en) * 2015-05-25 2017-01-04 美敦力公司 Fluid infusion device and manufacture method thereof including mechanical actuation means
CN106902420A (en) * 2015-12-23 2017-06-30 美敦力公司 For the fluid infusion apparatus being administered to patient
CN106999672A (en) * 2014-12-08 2017-08-01 赛诺菲 Drive mechanism for delivery device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH294905A (en) * 1951-03-19 1953-11-30 Scherer Corp R P Jet injection syringe.
CN104703640A (en) * 2012-10-04 2015-06-10 欧文蒙福德有限公司 Pen injector apparatus
CN106999672A (en) * 2014-12-08 2017-08-01 赛诺菲 Drive mechanism for delivery device
CN106267459A (en) * 2015-05-25 2017-01-04 美敦力公司 Fluid infusion device and manufacture method thereof including mechanical actuation means
CN106902420A (en) * 2015-12-23 2017-06-30 美敦力公司 For the fluid infusion apparatus being administered to patient

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