CN111281462A

CN111281462A - Plugging device with two ends without outwards protruding point structures

Info

Publication number: CN111281462A
Application number: CN201910355451.XA
Authority: CN
Inventors: 张瑾; 张健; 孙锟; 吴弘; 马彩霞
Original assignee: Shanghai Jinkui Medical Devices Co ltd
Current assignee: Shanghai Jinkui Medical Devices Co ltd
Priority date: 2019-04-29
Filing date: 2019-04-29
Publication date: 2020-06-16
Also published as: CN111281462A9

Abstract

The invention discloses a plugging device without an outward protruding point structure at two ends, which comprises: a mesh body; the first closing-in line penetrates through a plurality of grids formed by the mesh wires at the first closing-in end so as to close the first closing-in end; and the second closing-in line penetrates through a plurality of grids formed by the mesh wires at the second closing-in end so as to realize closing-in of the second closing-in end. Compared with the plugging device with the threaded connecting piece in the prior art, the scheme of the invention can reduce the processing difficulty, reduce the defective rate and save the cost.

Description

Plugging device with two ends without outwards protruding point structures

Technical Field

The invention relates to an occluder without an outward protruding point structure at two ends, which is used for treating diseases requiring occlusion treatment, such as atrial septal defect, patent ductus arteriosus, ventricular septal defect, patent foramen ovale, left auricle, or blood vessel, other occlusion tissue cavities, and the like.

Background

In the prior art, the stopper is generally provided with a connecting member at one end thereof, and the connecting member is internally threaded to be connected with a conveyor to realize the conveying of the stopper. Because the internal thread processing degree of difficulty is higher, can produce higher defective percentage in the production process moreover, can cause the waste of raw and other materials and invalid cost of labor's improvement like this. With the development of the degradable occluder, the degradable occluder with the threaded connecting piece is difficult to manufacture, so the occluder with the structure without the protruding points at the two ends can be manufactured by adopting the method of the scheme. When treating tumor and vascular lesion, the plugging device can also be implanted into the supply vessel of the lesion organ to block the supply vessel and interrupt the blood supply, so as to achieve the purposes of controlling bleeding and treating tumor and vascular lesion. The occluding device may also be placed in some tissue cavities to close the tissue cavity and cut off the delivery of internal material.

In summary, the prior art is difficult to manufacture and increases the manufacturing cost due to the threaded connection of the occluding device.

Disclosure of Invention

The invention aims to overcome the defects that the connecting piece of the plugging device in the prior art is difficult to manufacture and increases the manufacturing cost because of the thread, and provides the plugging device with a structure without protruding points at two ends.

The invention solves the technical problems through the following technical scheme:

the utility model provides a plugging device of both ends no evagination point structure which characterized in that, it is including:

the net-shaped body is provided with a first closed end and a second closed end which are oppositely arranged;

the first closing-in line penetrates through a plurality of grids formed by the mesh wires at the first closing-in end so as to close the first closing-in end;

and the second closing-in line penetrates through a plurality of grids formed by the mesh wires at the second closing-in end so as to close the second closing-in end.

Preferably, the first and second necked-in ends are free of outward protruding points.

In this scheme, first holding end and second holding end do not all have evagination point and refer to: the outer surface of the stopper where the two closed ends of the stopper are located is a flat and smooth surface. By adopting the arrangement, on one hand, the smooth outer surface of the plugging device without the structure of the outward protruding points at the two ends is more favorable for endothelial cells to climb, so that endothelialization can be quickly formed on the surface of the plugging device, the endothelialization time is shortened, and the recovery period after operation is also shortened; on the other hand, the occluder without the protruding point structures at the two ends has little damage to the surrounding tissues.

Preferably, the second closing-up line has an annular closing-up line, the annular closing-up line is inserted into a plurality of grids formed by the mesh wires at the second closing-up end to close up the second closing-up end, and the annular closing-up line is used as a connecting part to be connected with a conveyor for conveying the stopper with the two ends having no protruding point structure.

Preferably, the second closing-up line has an annular closing-up line and a conveying line, the annular closing-up line is inserted into a plurality of grids formed by the mesh wire at the second closing-up end to close up the second closing-up end, and two ends of the conveying line are respectively connected to the annular closing-up line to be connected with a conveyor for conveying the stopper with the structure without protruding points at the two ends.

With the arrangement, the conveying line can be easily engaged by the connecting part of the conveyor, and the conveying can be realized more reliably.

Preferably, the material of the mesh body, the first closing line and the second closing line is implantable material and is selected from at least one of the following materials:

(1) metals and their alloy materials, including stainless steel, cobalt-based alloys, titanium and titanium alloys, nickel titanium alloy shape memory materials;

(2) non-degradable bio-inert medical high molecular material, including nylon, polyester resin, polytetrafluoroethylene, ultra-high molecular weight polyethylene, high density polyethylene, polymethyl methacrylate, polypropylene, polycarbonate, polyurethane, organosilicon, polyacrylonitrile;

(3) degradable biomedical materials, including polylactide, polyglycolide, polycaprolactone, polydioxanone, and copolymers or mixtures of these materials.

The material of the mesh body, the first closing line and the second closing line may be selected from one or more materials in any one of the categories (1) to (3), or from one or more materials in two or more categories (1) to (3).

Preferably, the mesh body is manufactured by a mesh weaving or 3D printing method.

Preferably, a fiber fabric, a non-woven fabric or a film is arranged inside the stopper with the structure that the two ends have no protruding points.

By adopting the arrangement, the fiber fabric, the non-woven fabric or the film can be used for endothelial tissue cells to climb, and the blocking of the apparatus to blood or body fluid is increased.

Preferably, the occluder without the protruding point structure at both ends is: atrial septal defect occluder, patent ductus arteriosus occluder, ventricular septal defect occluder, patent foramen ovale occluder, left atrial appendage occluder, or vascular plug.

On the basis of the common knowledge in the field, the above preferred conditions can be combined randomly to obtain the preferred embodiments of the invention.

The positive progress effects of the invention are as follows:

the invention discloses a plugging device with two ends without an outward protruding point structure, wherein two ends can be closed by a closing line to form an annular structure, and the closing line or a conveying line can be caught by a conveyor to realize the conveying of the plugging device; compared with the plugging device with the threaded connecting piece in the prior art, the scheme of the invention can reduce the processing difficulty, reduce the defective rate and save the cost. The occluder without the structures with the outward protruding points at the two ends has good fitting performance, can safely and effectively occlude the heart defect or the patent position, greatly reduces the residual shunt of the ultrasonic examination after the operation, and can also avoid or reduce the adhesion of blood platelets at the exposed riveting points on the traditional occluder with the riveting points at the two ends, thereby reducing the risk of local thrombosis of the occluder and fundamentally reducing the occurrence of postoperative complications of the occluder. The occluder with the structure without the outward protruding points at the two ends can also be used for treating tumor and vascular lesions, and the occluder is implanted into the supply vessel of a lesion organ to occlude the supply vessel and interrupt the blood supply, so as to achieve the purposes of controlling bleeding and treating tumor and vascular lesions. The occluder with the structure without the outward protruding points at the two ends can also be placed in certain tissue cavities to close the tissue cavities and cut off the transportation of internal substances.

Drawings

Fig. 1 is a front view of an occluder without an outward protruding point structure at two ends in embodiment 1 of the present invention.

Fig. 2 is a schematic rear view of the occluder without the structure having protruding points at two ends in embodiment 1 of the present invention.

Fig. 3 is an enlarged schematic view of a central portion of fig. 1.

Fig. 4 is a schematic bottom view of the occluder without the structure having protruding points at both ends in example 1.

Fig. 5 is a schematic perspective view of the occluder without the structure having protruding points at two ends in embodiment 1 of the present invention.

Figure 6 is a partial perspective view of the occluder without an outward protruding point structure at two ends in example 2 of the present invention at the second necked-in end.

Description of reference numerals:

1: plugging device with two ends without outwards protruding point structures

10: net-shaped body

11: first closing end

12: second closing end

20: first closing line

30: second closing-in line

31: annular closing line

32: conveying line

Detailed Description

The present invention will be more clearly and completely described in the following description of preferred embodiments, taken in conjunction with the accompanying drawings.

Example 1

As shown in fig. 1-5, the occluder 1 without protruding point structure at both ends comprises: a mesh body 10, a first mouth line 20 and a second mouth line 30. The structure of the reticular body 10 is similar to that of the prior art, and comprises two net disks, and membranes for endothelial cells to climb are sewed in the two net disks. In this embodiment, the two net disks are both concave and have the same concave direction.

The net-shaped body 10 has a first closed end 11 and a second closed end 12 which are oppositely arranged, and the first closed end 11 and the second closed end 12 are both free of outward protruding points. Fig. 1 is preceded by a second, necked-in end 12, and fig. 2 is preceded by a first, necked-in end 11. The first closing-in line 20 is arranged through a plurality of grids formed by the net wires at the first closing-in end 11 to close the first closing-in end 11. The second closing-in line 30 is arranged through a plurality of grids formed by the net wires at the second closing-in end 12 to close the second closing-in end 12. The second closing-in line 30 has an annular closing-in line, the annular closing-in line is inserted into a plurality of grids formed by the mesh wires at the second closing-in end 12 to close the second closing-in end 12, and the annular closing-in line is used as a connecting part to be connected with a conveyor for conveying the stopper without an outward protruding point structure at two ends.

In this embodiment, the mesh body, the first closing line and the second closing line are all made of implantable materials, specifically, nitinol shape memory materials. In other alternative embodiments, the material of the mesh body, the first closing line and the second closing line may also be one or more of metals and alloys thereof, such as stainless steel, cobalt-based alloy, titanium and titanium alloy, non-degradable bio-inert medical polymer material, such as one or more of nylon, polyester resin, polytetrafluoroethylene, ultra-high molecular weight polyethylene, high density polyethylene, polymethyl methacrylate, polypropylene, polycarbonate, polyurethane, silicone, polyacrylonitrile, etc., and degradable biomedical material, such as one or more of polylactide, polyglycolide, polycaprolactone, polydioxanone, or copolymers or mixtures thereof.

Compared with the plugging device with the threaded connecting piece in the prior art, the scheme of the embodiment can reduce the use risk and increase the endothelialization speed.

In addition, the first and second closing ends have no outward protruding points, on one hand, the smooth outer surface of the occluder with the structure of which the two ends have no outward protruding points is more favorable for endothelial cells to climb, thus endothelialization can be quickly formed on the surface of the occluder, the endothelialization time is shortened, and the postoperative recovery period is also shortened; on the other hand, the occluder without the protruding point structures at the two ends has little damage to the surrounding tissues.

In this embodiment, the mesh body 10 is woven from mesh wire. In other alternative embodiments, the mesh-like body 10 may also be manufactured by a method of 3D printing.

In addition, in this embodiment, the inner part of the occluder without the structure of the protruding points at both ends is further provided with a thin film for endothelial tissue cells to climb, and the barrier of the apparatus to blood or body fluid is increased. In other alternative embodiments, the inner part of the occluder without the structure of the protruding points at the two ends can be further provided with a fiber fabric or a non-woven fabric for endothelial tissue cells to climb and increasing the barrier of the apparatus to blood or body fluid.

The occluder without the protruding point structure at the two ends can be as follows: atrial septal defect occluder, patent ductus arteriosus occluder, ventricular septal defect occluder, patent foramen ovale occluder, left atrial appendage occlusion or vascular plug, and can also be other medical instruments for closing tissue cavities.

Example 2

As shown in fig. 6, the present embodiment 2 is similar to embodiment 1 except that: in embodiment 1, the second closing line 30 includes only the annular closing line, whereas in embodiment 2, the second closing line 30 has the annular closing line 31 and the transfer line 32. The annular closing-in line 31 is arranged through a plurality of grids formed by the mesh wires at the second closing-in end 12 to close the second closing-in end 12, and two ends of the conveying line 32 are respectively connected to the annular closing-in line 31 to be connected with a conveyor for conveying the stopper 1 without an outward protruding point structure at two ends.

The feed line 32 can be easily engaged by the connecting member of the conveyor to more reliably carry out the feeding.

It should be noted that, the structure of the conveying line 32 may be set to be various structures according to actual needs, such as a semi-annular structure, a U-shaped structure, etc., as long as the conveying line 32 can be connected with the annular closing line 31 to realize connection with the conveyor of the stopper 1 having a structure without protruding points at both ends of the conveyor.

The annular mouth line 31 is shown thicker than in reality in fig. 6 for illustrative purposes only.

In describing the present invention, an embodiment may be provided with multiple figures, and reference numerals for like parts of the same embodiment are not necessarily shown in each figure; it will be appreciated by those skilled in the art that while one or more figures in an embodiment are described, they may be understood in conjunction with other figures in the embodiment; it will be understood by those skilled in the art that when no specific reference is made to which figure the text specifically corresponds, the text can be understood in conjunction with all of the figures in the embodiment.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.

While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that this is by way of example only, and that the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and scope of the invention, and these changes and modifications are within the scope of the invention.

Claims

1. The utility model provides a plugging device of both ends no evagination point structure which characterized in that, it is including:

2. The occlusion device of claim 1, wherein neither of the first and second necked-in ends are free of extrusions.

3. The occluder of claim 1, wherein the second converging line comprises an annular converging line passing through a plurality of cells formed by the mesh at the second converging end to close the second converging end, the annular converging line serving as a connection member to a conveyor for transporting the occluder without a structure having two ends with outwardly protruding points.

4. The occluder of claim 1, wherein the second converging line comprises an annular converging line passing through a plurality of meshes formed by the mesh at the second converging end to close the second converging end, and a transport line connected at both ends to the annular converging line for connection to a conveyor for transporting the occluder of the structure.

5. The occluder of claim 1, wherein the mesh, the first line of closure, and the second line of closure are all implantable materials selected from at least one of the following materials:

6. The occluder of claim 1 wherein said mesh is made by a method of mesh weaving or 3D printing.

7. The occluder of claim 1, wherein the occluder is provided with a fabric, a non-woven fabric or a film.

8. The occluder of any of claims 1-7 having a double-ended non-herniated dot structure, wherein said occluder has a double-ended non-herniated dot structure comprising: atrial septal defect occluder, patent ductus arteriosus occluder, ventricular septal defect occluder, patent foramen ovale occluder, left atrial appendage occluder, or vascular plug.