CN111269280B - 用于检测溶酶体贮积症相关酶的化合物、对应内标和试剂盒 - Google Patents
用于检测溶酶体贮积症相关酶的化合物、对应内标和试剂盒 Download PDFInfo
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- CN111269280B CN111269280B CN202010232077.7A CN202010232077A CN111269280B CN 111269280 B CN111269280 B CN 111269280B CN 202010232077 A CN202010232077 A CN 202010232077A CN 111269280 B CN111269280 B CN 111269280B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
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CN202010232077.7A CN111269280B (zh) | 2020-03-27 | 2020-03-27 | 用于检测溶酶体贮积症相关酶的化合物、对应内标和试剂盒 |
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CN202010232077.7A CN111269280B (zh) | 2020-03-27 | 2020-03-27 | 用于检测溶酶体贮积症相关酶的化合物、对应内标和试剂盒 |
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CN111269280A CN111269280A (zh) | 2020-06-12 |
CN111269280B true CN111269280B (zh) | 2021-07-13 |
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CN202010232077.7A Active CN111269280B (zh) | 2020-03-27 | 2020-03-27 | 用于检测溶酶体贮积症相关酶的化合物、对应内标和试剂盒 |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102014929A (zh) * | 2008-03-13 | 2011-04-13 | 珀金埃尔默健康科学有限公司 | 用于多种检测体系的酶底物 |
CN102943106A (zh) * | 2006-03-13 | 2013-02-27 | 珀金埃尔默健康科学股份有限公司 | 用于质谱法检测的底物和内标 |
CN105247068A (zh) * | 2013-03-15 | 2016-01-13 | 珀金埃尔默健康科学股份有限公司 | 与溶酶体贮积症的测试相关的化合物和方法 |
CN105636606A (zh) * | 2013-09-05 | 2016-06-01 | 华盛顿大学商业中心 | 用于筛查mps i、ii、iiia、iiib、iva、vi和vii的试剂和方法 |
CN107109462A (zh) * | 2014-09-02 | 2017-08-29 | 珀金埃尔默健康科学股份有限公司 | 涉及测试溶酶体贮积紊乱的方法 |
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2020
- 2020-03-27 CN CN202010232077.7A patent/CN111269280B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102943106A (zh) * | 2006-03-13 | 2013-02-27 | 珀金埃尔默健康科学股份有限公司 | 用于质谱法检测的底物和内标 |
CN102014929A (zh) * | 2008-03-13 | 2011-04-13 | 珀金埃尔默健康科学有限公司 | 用于多种检测体系的酶底物 |
CN105247068A (zh) * | 2013-03-15 | 2016-01-13 | 珀金埃尔默健康科学股份有限公司 | 与溶酶体贮积症的测试相关的化合物和方法 |
CN105636606A (zh) * | 2013-09-05 | 2016-06-01 | 华盛顿大学商业中心 | 用于筛查mps i、ii、iiia、iiib、iva、vi和vii的试剂和方法 |
CN107109462A (zh) * | 2014-09-02 | 2017-08-29 | 珀金埃尔默健康科学股份有限公司 | 涉及测试溶酶体贮积紊乱的方法 |
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Inventor after: Zhai Yanhong Inventor after: Sun Nian Inventor after: Wang Lihui Inventor after: Shi Haowei Inventor after: Gao Ya Inventor after: Ding Liang Inventor after: Wang Xiao Inventor after: Li Lin Inventor after: Cao Zheng Inventor after: Ma Zhijun Inventor after: Lu Kaizhi Inventor after: Cai Bolun Inventor after: Niu Yanyan Inventor after: Xiao Bingxin Inventor after: Pan Yuanyuan Inventor before: Li Lin Inventor before: Sun Nian Inventor before: Wang Lihui Inventor before: Shi Haowei Inventor before: Gao Ya Inventor before: Ding Liang Inventor before: Wang Xiao Inventor before: Zhai Yanhong Inventor before: Cao Zheng Inventor before: Ma Zhijun Inventor before: Lu Kaizhi Inventor before: Cai Bolun Inventor before: Niu Yanyan Inventor before: Xiao Bingxin Inventor before: Pan Yuanyuan |