CN111248322A - Polygonatum sibiricum and grapefruit tea and preparation method thereof - Google Patents
Polygonatum sibiricum and grapefruit tea and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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Abstract
The invention discloses a polygonatum sibiricum and grapefruit tea which is prepared from the following raw materials in percentage by mass: 16.2-72.5% of rhizoma polygonati, 8.1-43.5% of shaddock peel, 1.6-11.6% of dogwood, 1.6-14.5% of cassia seed, 1.6-14.5% of medlar and 1.6-14.5% of red date, wherein the total mass of the components is 100%.
Description
Technical Field
The invention belongs to the technical field of medical health-care products, relates to a polygonatum sibiricum and grapefruit tea and further relates to a preparation method of the polygonatum sibiricum and grapefruit tea.
Background
With the acceleration of the pace of life and the increase of working pressure in modern society, the change of diet rules leads to the gradual increase and the youthful occurrence of cardiovascular diseases, especially the incidence rate of myocardial infarction. In the health food management method published by the Ministry of health in 1996, some Chinese medicinal herbs with dual purposes of medicine and food are allowed to be prepared into health products. Therefore, the use of traditional Chinese medicines in China to prevent cardiovascular diseases and improve the state of sub-health people gradually becomes a research hotspot.
The traditional Chinese medicine classifies the myocardial infarction into the categories of 'obstruction of qi in the chest' and 'palpitation', and the pathogenesis of the myocardial infarction is mainly 'obstruction of qi deficiency, blood stasis and collaterals', which is the syndrome of principal deficiency and secondary excess. Qi deficiency and yin deficiency are the pathological basis of the disease, blood stasis is the principal and the pathogenesis of principal deficiency and secondary excess runs through the whole course of myocardial infarction. Heart qi is the source of power for promoting blood circulation, and abundant heart qi can ensure normal beating rhythm of heart and blood circulation. Qi deficiency can not reach blood vessels and can cause blood stasis. Because qi deficiency causes the body to promote and transform qi, blood stasis will inevitably affect the function of heart governing blood vessels, and further induce myocardial infarction.
Tea therapy is a common conditioning mode in people's life, and the method is simple and convenient, can preserve health and treat diseases, and is deeply loved by people. In recent years, the nutritional effect and the pharmacological effect of the tea are continuously discovered by people, and the health-care function and the disease prevention and treatment effect of the tea are ensured.
Disclosure of Invention
The invention aims to provide polygonatum sibiricum and grapefruit tea which can improve the cardiac function and prevent and protect myocardial cells.
The invention also aims to provide a preparation method of the polygonatum sibiricum grapefruit tea.
The invention adopts the technical scheme that the sealwort grapefruit tea is prepared from the following raw materials in percentage by mass:
16.2 to 72.5 percent of rhizoma polygonati, 8.1 to 43.5 percent of shaddock peel, 1.6 to 11.6 percent of dogwood, 1.6 to 14.5 percent of cassia seed, 1.6 to 14.5 percent of medlar and 1.6 to 14.5 percent of red date, wherein the total mass of the components is 100 percent.
It is preferable that
25.3 to 61.2 percent of rhizoma polygonati, 12.7 to 40.8 percent of shaddock peel, 2.5 to 12.2 percent of dogwood, 2.5 to 16.3 percent of cassia seed, 2.5 to 12.2 percent of medlar and 2.5 to 12.2 percent of red date, wherein the total mass of the components is 100 percent.
The drinking method is directly drinking tea, tea bag or tea soup.
The invention adopts another technical scheme that a preparation method of polygonatum sibiricum and grapefruit tea is specifically carried out according to the following steps:
step 1, weighing each raw material according to the mass percentage, and backing up;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water for boiling, adding salt after boiling, continuing to cook, fishing out the shaddock peel after cooking, and squeezing and dehydrating to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into the dried shaddock peels, putting the dried shaddock peels into water, decocting and filtering to obtain filtrate;
and 5, putting the eluent obtained in the step 2 and the filtrate obtained in the step 3 into a homogenizer, performing primary homogenization treatment, adding auxiliary materials, performing secondary homogenization treatment, performing microfiltration and sterilization to obtain the sealwort grapefruit tea.
In the step 2, during extraction, the mass ratio of rhizoma polygonati to distilled water is 1: 20-25, the extraction temperature is 70-80 ℃, the extraction time is 2-6 h, and during two times of elution, the mass ratio of rhizoma polygonati to ethanol is 1:3 to 5.
In the step 2, the macroporous adsorption resin is any one of ADS-17 or ADS-F8.
In the step 3, the boiling time is 5-8 min, the salt content is 5-10%, the cooking time is 10-15 min, and the water content of the dehydrated shaddock peel is 20-30%.
In the step 4, the mass ratio of the raw materials to the water is 1: 3-8, wherein the decoction temperature is 50-90 ℃, and the decoction time is 2.5-5 h.
In the step 5, the auxiliary materials comprise sucrose, potassium sorbate, lactic acid and sodium chloride, wherein the sucrose accounts for 4-6% of the solution, the potassium sorbate accounts for 0.03-0.05% of the solution, the lactic acid accounts for 0.3-0.75% of the solution, and the sodium chloride accounts for 0.1-0.5% of the solution.
In step 5, the homogenization temperature is 55-65 ℃, the homogenization pressure is 20-25 MPa, the homogenization time is 5-10 min, the aperture of the microfiltration membrane during microfiltration is 0.1-1.0 mu m, the microfiltration pressure is 0.15-0.40 MPa, and the sterilization temperature is 115-120 ℃.
The invention has the beneficial effects that the prepared polygonatum sibiricum and grapefruit tea has reasonable formula, good taste, convenient drinking and suitability for four seasons, and pharmacological tests prove that the raw materials are reasonably matched to achieve the synergistic effect, so that the polygonatum sibiricum and grapefruit tea has the effects of improving the cardiac function and preventing and protecting myocardial cells, and is an ideal health-care beverage.
Drawings
FIG. 1 is the SOD diagram of the sealwort grapefruit tea prepared by the invention;
FIG. 2 is a GSH-Px diagram of the sealwort grapefruit tea prepared by the invention;
FIG. 3 is a CK-MB diagram of a polygonatum sibiricum grapefruit tea prepared according to the present invention;
FIG. 4 is a cTnT diagram of the sealwort grapefruit tea prepared by the invention.
Detailed Description
The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
The invention relates to a polygonatum sibiricum and grapefruit tea which is prepared from the following raw materials in percentage by mass:
16.2 to 72.5 percent of rhizoma polygonati, 8.1 to 43.5 percent of shaddock peel, 1.6 to 11.6 percent of dogwood, 1.6 to 14.5 percent of cassia seed, 1.6 to 14.5 percent of medlar and 1.6 to 14.5 percent of red date, wherein the total mass of the components is 100 percent.
It is preferable that
25.3 to 61.2 percent of rhizoma polygonati, 12.7 to 40.8 percent of shaddock peel, 2.5 to 12.2 percent of dogwood, 2.5 to 16.3 percent of cassia seed, 2.5 to 12.2 percent of medlar and 2.5 to 12.2 percent of red date, wherein the total mass of the components is 100 percent.
The drinking method is directly drinking tea, tea bag or tea soup.
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing each raw material according to the mass percentage, and backing up;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water for boiling, adding salt after boiling, continuing to cook, fishing out the shaddock peel after cooking, and squeezing and dehydrating to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into the dried shaddock peels, putting the dried shaddock peels into water, decocting and filtering to obtain filtrate;
and 5, putting the eluent obtained in the step 2 and the filtrate obtained in the step 3 into a homogenizer, performing primary homogenization treatment, adding auxiliary materials, performing secondary homogenization treatment, performing microfiltration and sterilization to obtain the sealwort grapefruit tea.
In the step 2, during extraction, the mass ratio of rhizoma polygonati to distilled water is 1: 20-25, the extraction temperature is 70-80 ℃, the extraction time is 2-6 h, and during two times of elution, the mass ratio of rhizoma polygonati to ethanol is 1:3 to 5.
In the step 2, the macroporous adsorption resin is any one of ADS-17 or ADS-F8.
In the step 3, the boiling time is 5-8 min, the salt content is 5-10%, the cooking time is 10-15 min, and the water content of the dehydrated shaddock peel is 20-30%.
In the step 4, the mass ratio of the raw materials to the water is 1: 3-8, wherein the decoction temperature is 50-90 ℃, and the decoction time is 2.5-5 h.
In the step 5, the auxiliary materials comprise sucrose, potassium sorbate, lactic acid and sodium chloride, wherein the sucrose accounts for 4-6% of the solution, the potassium sorbate accounts for 0.03-0.05% of the solution, the lactic acid accounts for 0.3-0.75% of the solution, and the sodium chloride accounts for 0.1-0.5% of the solution.
In step 5, during two homogenization treatments, the homogenization temperature is 55-65 ℃, the homogenization pressure is 20-25 MPa, the homogenization time is 5-10 min, the aperture of the microfiltration membrane during microfiltration is 0.1-1.0 μm, the microfiltration pressure is 0.15-0.40 MPa, and the sterilization temperature is 115-120 ℃.
The functions and the main indications of the raw materials in the traditional Chinese medicine composition are as follows:
rhizoma polygonati: is dried rhizome of Polygonatum sibiricum of Liliaceae, and has mild nature and dry taste, and enters spleen, lung and kidney meridians. Has effects of invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney, and is suitable for treating syndrome of weakness of spleen and stomach, tiredness, debilitation, xerostomia, anorexia, lung deficiency, dry cough, and dizziness, soreness of waist and knees, premature gray hair, internal heat, diabetes, etc. caused by deficiency of kidney essence.
Shaddock peel: is pericarp of Citrus grandis of Rutaceae, with warm nature, pungent, sweet and bitter taste, and enters spleen, lung and kidney meridians. Has the effects of relieving epigastric distention, regulating qi, promoting digestion, reducing phlegm, relieving cough and asthma. It is commonly indicated for qi stagnation, chest distress, abdominal cold pain, food stagnation, diarrhea and dysentery, cough and dyspnea, and Xianqi.
Dogwood fruit: is the mature pulp of dogwood belonging to the family Cornaceae, which is slightly warm in nature, sour and astringent in taste and enters liver and kidney meridians. Has the efficacy of tonifying liver and kidney. It is commonly used for liver and kidney deficiency, dizziness and blurred vision.
Cassia seed: is dry mature seed of Cassia tora or Cassia tora L.of Leguminosae, is slightly cold in nature, bitter, sweet and salty in taste, enters liver, kidney and large intestine channels, and has the effects of clearing liver, improving eyesight, reducing blood fat and lowering blood pressure.
Medlar: is mature fruit of Lycium chinense Mill of Solanaceae. Has mild nature and sweet taste, enters liver and kidney channels, has the effects of improving eyesight, replenishing vital essence and nourishing liver and kidney, and is mainly used for patients with consumptive disease, essence deficiency, soreness of waist and knees, dizziness and tinnitus.
Red dates: is mature fruit of deciduous shrub or small tree of Rhamnaceae. Warm in nature, sweet in taste, and has the effects of invigorating spleen and stomach channels, invigorating spleen-stomach, benefiting qi, nourishing blood, and tranquilizing.
Second, example
Example 1
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 72.5% of rhizoma polygonati, 8.1% of shaddock peel, 10.4% of dogwood, 1.6% of cassia seed, 1.6% of medlar and 5.8% of red date according to the mass for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 5min, adding 10% of salt to continuously boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 30% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of the raw materials to the water is 1:8, decocting, filtering, and decocting at the temperature of 50 ℃ for 2.5 hours to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer, adding cannabidiol, carrying out primary homogenization treatment, adding 4% of sucrose, 0.04% of potassium sorbate, 0.75% of lactic acid and 0.1% of sodium chloride, carrying out secondary homogenization treatment at 55 ℃, 25MPa for 7min, carrying out microfiltration, wherein the pore diameter of a microfiltration membrane is 1.0 mu m during microfiltration, the microfiltration pressure is 0.15MPa, and carrying out sterilization at 120 ℃ to obtain the sealwort tea.
Example 2
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 61.2% of rhizoma polygonati, 12.7% of shaddock peel, 11.6% of dogwood, 2.5% of cassia seed, 2.5% of medlar and 9.5% of red date for backup;
and 2, crushing rhizoma polygonati, extracting for 6 hours by using distilled water under reflux, wherein the mass ratio of the rhizoma polygonati to the distilled water is 1:20, the extraction temperature is 80 ℃, filtering, separating the filtrate by using ADS-F8 type macroporous adsorption resin, eluting by using 20% ethanol firstly, then 50% ethanol, collecting the eluent, and when the two elutions are carried out, the mass ratio of the rhizoma polygonati to the ethanol is 1: 5;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 8min, adding 5% of salt to continue to boil for 15min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 20% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:3, decocting, filtering, and decocting at 90 ℃ for 5 hours to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for primary homogenization treatment, adding 5% of sucrose, 0.05% of potassium sorbate, 0.3% of lactic acid and 0.2% of sodium chloride, performing secondary homogenization treatment at 65 ℃, 24MPa for 5min, carrying out microfiltration, sterilizing at 118 ℃ and obtaining the sealwort and grapefruit tea, wherein the pore diameter of a microfiltration membrane is 0.1 mu m and the microfiltration pressure is 0.40 MPa.
Example 3
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 30.7% of rhizoma polygonati, 43.5% of shaddock peel, 1.6% of dogwood, 16.3% of cassia seed, 6.3% of wolfberry fruit and 1.6% of red date for backup;
and 2, crushing rhizoma polygonati, extracting for 5 hours by using distilled water under reflux, wherein the mass ratio of the rhizoma polygonati to the distilled water is 1:21, the extraction temperature is 75 ℃, filtering, separating the filtrate by using ADS-F8 type macroporous adsorption resin, eluting by using 40% ethanol firstly, then using 70% ethanol, collecting the eluent, and when the two elutions are carried out, the mass ratio of the rhizoma polygonati to the ethanol is 1: 4;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 7min, adding 8% of salt to continuously boil for 13min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 28% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:5, decocting, filtering, and decocting for 3 hours at the decocting temperature of 60 ℃ to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for primary homogenization treatment, adding 6% of sucrose, 0.03% of potassium sorbate, 0.5% of lactic acid and 0.5% of sodium chloride, performing secondary homogenization treatment at the homogenization temperature of 60 ℃, the homogenization pressure of 20MPa and the homogenization time of 10min, performing microfiltration, wherein the pore diameter of a microfiltration membrane is 0.22 mu m during microfiltration, the microfiltration pressure is 0.30MPa, and performing sterilization at the sterilization temperature of 115 ℃ to obtain the polygonatum grapefruit tea.
Example 4
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 31.5% of rhizoma polygonati, 15.1% of shaddock peel, 12.2% of dogwood, 14.5% of cassia seed, 14.5% of medlar and 12.2% of red date for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 5min, adding 10% of salt to continuously boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 30% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:6, decocting, filtering, and decocting at the temperature of 50 ℃ for 2.5 hours to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for first homogenization treatment, adding 4% of sucrose, 0.03% of potassium sorbate, 0.75% of lactic acid and 0.5% of sodium chloride, homogenizing at 57 ℃, homogenizing at 25MPa for 8min, carrying out microfiltration, sterilizing at 120 ℃ and obtaining the sealwort and pomelo tea, wherein the pore diameter of a microfiltration membrane is 0.5 mu m and the microfiltration pressure is 0.15MPa during microfiltration.
Example 5
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 25.3% of rhizoma polygonati, 40.8% of shaddock peel, 2.5% of dogwood, 4.7% of cassia seed, 12.2% of wolfberry fruit and 14.5% of red date for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 6min, adding 6% of salt to continue to boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 20% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:6, decocting, filtering, and decocting for 3 hours at the decocting temperature of 50 ℃ to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for first homogenization treatment, adding 4% of sucrose, 0.03% of potassium sorbate, 0.75% of lactic acid and 0.5% of sodium chloride, homogenizing at 57 ℃, homogenizing at 25MPa for 8min, carrying out microfiltration, sterilizing at 116 ℃, and thus obtaining the polygonatum-shaddock tea, wherein the pore diameter of a microfiltration membrane is 1.0 mu m during microfiltration, and the microfiltration pressure is 0.15 MPa.
Example 6
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 16.2% of rhizoma polygonati, 41.2% of shaddock peel, 11.6% of dogwood, 16.3% of cassia seed, 12.2% of wolfberry fruit and 2.5% of red date for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 8min, adding 7% of salt to continue to boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 24% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:3, decocting, filtering, and decocting for 5 hours at the decocting temperature of 60 ℃ to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for first homogenization treatment, adding 5% of sucrose, 0.04% of potassium sorbate, 0.65% of lactic acid and 0.5% of sodium chloride, homogenizing at the temperature of 60 ℃, the homogenization pressure of 20MPa, the homogenization time of 8min, then carrying out microfiltration, wherein the pore diameter of a microfiltration membrane during microfiltration is 1.0 mu m, the microfiltration pressure is 0.40MPa, and sterilizing at the sterilization temperature of 115 ℃ to obtain the sealwort pomelo tea.
Third, clinical experimental data:
1. the test method comprises the following steps:
60 rats were divided into 5 groups of 12 rats each, i.e., sham surgery group, model group, invention group 1, invention group 2, and invention group 3. After 3 days of adaptive feeding, rats freely eat and drink water, each invention group is continuously administrated by gastric lavage for 7 days, the other two groups are administrated with normal saline with equal volume, and each group is administrated once a day. After the seventh day of administration, the patient was connected with an electrocardiogram, intubated with trachea, and connected with an animal respirator. The chest is opened between the 3 rd to 4 th ribs of the left chest to expose the heart. The left anterior descending branch of the coronary artery is punctured and ligated by a suture needle with the left main coronary artery as a mark between the left auricle and the pulmonary artery cone. The successful ligation is determined by observing the indexes of ST-segment elevation of II-lead electrocardiogram and observing the myocardial ischemia such as whitening of tissues below the ligation region with naked eyes. The sham group performed the same procedure except that the coronary artery was not ligated. The ischemia/reperfusion (I/R) model was established by releasing the ligature and reperfusion for 4h 30min after ischemia. Measuring relevant indexes such as hemodynamics, myocardial enzyme and antioxidation.
The sham operation group: only the thread was not ligated, and physiological saline was administered.
Model group: threaded and ligated, and given physiological saline.
Invention group 1: the sealwort grapefruit tea beverage prepared in the application example 1.
Invention group 2: the sealwort grapefruit tea beverage prepared in the application example 2.
Invention group 3: the sealwort grapefruit tea beverage prepared in the application example 3.
2. Test results and conclusions:
2.1 the effect of the sealwort grapefruit tea on the heart function of rats is prevented, after the rat sealwort grapefruit tea is given for 7 days, the heart function of the rats is obviously improved, and the difference has statistical significance, as shown in Table 1.
TABLE 1 comparison of cardiac function indices of the groups of test rats
Note: compared with the group of the pseudo-operation,##P<0.01and#p is less than 0.05; in comparison with the set of models,**p<0.01and*p<0.05,(mean±SD,n=12)。
2.2 the detection results of the antioxidant related indexes of the sealwort grapefruit tea on the myocardial oxidation indexes of rats are shown in the figure 1 and the figure 2: the sealwort grapefruit tea can obviously prevent myocardial ischemia reperfusion injury rat myocardial cell oxidation, obviously improve GSH-Px level and inhibit SOD activity.
2.3 the effect of the sealwort grapefruit tea on rat myocardial enzyme indexes rat myocardial enzyme detection index results are shown in fig. 3 and 4: compared with a model group, the cinnamon fruit wine can obviously reduce the content of CK-MB and cTnT of a rat with myocardial ischemia-reperfusion injury.
In conclusion, the polygonatum sibiricum grapefruit tea can effectively increase the left ventricular systolic pressure LVSP, the left ventricular diastolic end pressure LVEDP, the maximum rising rate (+ dp/dtmax) of the left ventricular systolic pressure and the maximum falling rate (-dp/dtmax) of the left ventricular diastolic pressure, and can effectively improve the cardiac function; compared with the model group, the content of glutathione peroxidase (GSH-Px) and superoxide dismutase SOD in the invention group is more than 6%, and the content of myocardial enzyme creatine kinase isoenzyme CK-MB and troponin T (cTnT) is less than 12%, thus effectively preventing myocardial damage and slowing down the incidence of myocardial infarction.
Claims (10)
1. The sealwort grapefruit tea is characterized by comprising the following raw materials in percentage by mass:
16.2 to 72.5 percent of rhizoma polygonati, 8.1 to 43.5 percent of shaddock peel, 1.6 to 11.6 percent of dogwood, 1.6 to 14.5 percent of cassia seed, 1.6 to 14.5 percent of medlar and 1.6 to 14.5 percent of red date, wherein the total mass of the components is 100 percent.
2. The sealwort grapefruit tea as claimed in claim 1, which is characterized by comprising the following raw materials in percentage by mass:
25.3 to 61.2 percent of rhizoma polygonati, 12.7 to 40.8 percent of shaddock peel, 2.5 to 12.2 percent of dogwood, 2.5 to 16.3 percent of cassia seed, 2.5 to 12.2 percent of medlar and 2.5 to 12.2 percent of red date, wherein the total mass of the components is 100 percent.
3. The sealwort grapefruit tea according to claim 1 or 2, characterized in that the drinking method is direct drinking, tea bag making or tea soup.
4. A method for preparing polygonatum sibiricum grapefruit tea according to claim 1 or 2, which is characterized by comprising the following steps:
step 1, weighing each raw material according to the mass percentage, and backing up;
step 2, crushing rhizoma polygonati, performing reflux extraction by using distilled water, then filtering, separating filtrate by using macroporous adsorption resin, eluting by using 20-40% ethanol, eluting by using 50-70% ethanol, and collecting eluent;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water for boiling, adding salt after boiling, continuing to cook, fishing out the shaddock peel after cooking, and squeezing and dehydrating to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into the dried shaddock peels, putting the dried shaddock peels into water, decocting and filtering to obtain filtrate;
and 5, putting the eluent obtained in the step 2 and the filtrate obtained in the step 3 into a homogenizer, performing primary homogenization treatment, adding auxiliary materials, performing secondary homogenization treatment, performing microfiltration and sterilization to obtain the sealwort grapefruit tea.
5. The preparation method of rhizoma polygonati shaddock tea according to claim 4, wherein in the step 2, during extraction, the mass ratio of rhizoma polygonati to distilled water is 1: 20-25, the extraction temperature is 70-80 ℃, the extraction time is 2-6 h, and during two elutions, the mass ratio of rhizoma polygonati to ethanol is 1:3 to 5.
6. The method for preparing rhizoma polygonati pomelo tea according to claim 4, wherein in the step 2, the macroporous adsorption resin is any one of ADS-17 or ADS-F8.
7. The preparation method of the sealwort grapefruit tea according to claim 4, wherein in the step 3, the boiling time is 5-8 min, the salt content is 5-10%, the cooking time is 10-15 min, and the water content of dehydrated grapefruit peel is 20-30%.
8. The preparation method of rhizoma polygonati shaddock tea according to claim 4, wherein in the step 4, the mass ratio of the raw materials to the water is 1: 3-8, wherein the decoction temperature is 50-90 ℃, and the decoction time is 2.5-5 h.
9. The method for preparing a polygonatum sibiricum shaddock tea according to claim 4, wherein in the step 5, the auxiliary materials are sucrose, potassium sorbate, lactic acid and sodium chloride, wherein the sucrose accounts for 4-6% of the solution, the potassium sorbate accounts for 0.03-0.05% of the solution, the lactic acid accounts for 0.3-0.75% of the solution, and the sodium chloride accounts for 0.1-0.5% of the solution.
10. The method for preparing a polygonatum sibiricum grapefruit tea according to claim 4, wherein in the step 5, the homogenization temperature is 55-65 ℃, the homogenization pressure is 20-25 MPa, the homogenization time is 5-10 min, the pore diameter of a microfiltration membrane during microfiltration is 0.1-1.0 μm, the microfiltration pressure is 0.15-0.40 MPa, and the sterilization temperature is 115-120 ℃.
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