CN111182942A - Broadband electromagnetic resonator for therapeutic treatment of a pathological focus in a tissue of a living being, medical device for therapeutic treatment and method of therapeutic treatment - Google Patents
Broadband electromagnetic resonator for therapeutic treatment of a pathological focus in a tissue of a living being, medical device for therapeutic treatment and method of therapeutic treatment Download PDFInfo
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36125—Details of circuitry or electric components
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03B—GENERATION OF OSCILLATIONS, DIRECTLY OR BY FREQUENCY-CHANGING, BY CIRCUITS EMPLOYING ACTIVE ELEMENTS WHICH OPERATE IN A NON-SWITCHING MANNER; GENERATION OF NOISE BY SUCH CIRCUITS
- H03B5/00—Generation of oscillations using amplifier with regenerative feedback from output to input
- H03B5/02—Details
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03B—GENERATION OF OSCILLATIONS, DIRECTLY OR BY FREQUENCY-CHANGING, BY CIRCUITS EMPLOYING ACTIVE ELEMENTS WHICH OPERATE IN A NON-SWITCHING MANNER; GENERATION OF NOISE BY SUCH CIRCUITS
- H03B5/00—Generation of oscillations using amplifier with regenerative feedback from output to input
- H03B5/08—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance
- H03B5/12—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance active element in amplifier being semiconductor device
- H03B5/1206—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance active element in amplifier being semiconductor device using multiple transistors for amplification
- H03B5/1212—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance active element in amplifier being semiconductor device using multiple transistors for amplification the amplifier comprising a pair of transistors, wherein an output terminal of each being connected to an input terminal of the other, e.g. a cross coupled pair
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03B—GENERATION OF OSCILLATIONS, DIRECTLY OR BY FREQUENCY-CHANGING, BY CIRCUITS EMPLOYING ACTIVE ELEMENTS WHICH OPERATE IN A NON-SWITCHING MANNER; GENERATION OF NOISE BY SUCH CIRCUITS
- H03B5/00—Generation of oscillations using amplifier with regenerative feedback from output to input
- H03B5/08—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance
- H03B5/12—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance active element in amplifier being semiconductor device
- H03B5/1231—Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance active element in amplifier being semiconductor device the amplifier comprising one or more bipolar transistors
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Abstract
An apparatus for generating a Fermi-past-ula (FPU) spectrum comprises a resonator for creating an electromagnetic FPU spectrum (FPU resonator), the resonator comprising: a two-arm generator for generating oscillations, each arm of which comprises a coil, a capacitor and a non-linearly controllable electronic component, wherein the aforementioned coils of the two-arm generator are oppositely wound, oppositely connected, having the same number of turns of the same diameter, and the turns of one coil are arranged in an alternating manner between the turns of the other coil, and further the generator arms are connected such that they provide for creating oscillations by means of positive feedback between the generator arms; a power supply unit for transmitting power to a connection point of the coil; and a trigger circuit connected to the two-arm generator. A medical device for the therapeutic treatment of a pathological focus in a tissue of an organism and a method of therapeutic treatment of a pathological focus in a tissue of an organism by means of a resonance effect on a FPU reconstruction spectrum in a tissue of an organism are also presented.
Description
Technical Field
The present invention relates to medical devices, and more particularly to devices, medical devices and methods for therapeutically affecting lesions in body tissue by radiating electromagnetic fields having structures with Fermi-Pasta-ullam (FPU) recurring spectra.
Medical devices and methods may be used to treat inflammatory processes and arrhythmias in the body, to coordinate the functioning of organs and to enhance body defenses.
Background
An electronic device for electrical stimulation is known in the prior art (see for example RU 2135226C 1) which is intended for therapeutic non-invasive individual dose influence on an area of human skin by electrical impulses in order to exert a general regulatory influence on the physiological system of the body and to provide an analgesic effect, the influence being determined from the batch of selected zones and periodic over time.
The electrical stimulator comprises means for generating influencing pulses, means for generating a modulation control signal, a controlled generator, a first electrode and a second electrode, means for analyzing the adaptation process, a stimulation channel switching unit, 2N-2 electrodes, an electrode impact frequency generator and a channel code former, wherein a clock output of the means for generating influencing pulses is connected to a clock input of the means for adapting the process analysis and the electrode impact frequency generator, a control input of the electrode impact frequency generator is connected to a second control output of the means for adapting the process analysis, and an output is connected to a count input of the channel code former; the first and second outputs of the ith (I ═ I, N) batch of outputs of the means for switching stimulation channels are connected through the ith batch of first and second electrodes of the batch of 2N electrodes, respectively, and the second signal output of the means for generating output pulses is connected to the second signal input of the means for switching stimulation channels.
The human body is considered to be a complex system, which is divided into a plurality of interrelated subsystems or interacting organs that operate with complete integrity according to the concept of system analysis.
In this case, transdermal exposure under therapeutic non-invasive influence should be applied over a set of selected areas to allow seeking an effective influence on a collection of human organs.
The particular need for transcutaneous influence of a range of selected areas (indeed a range of organs) also arises in the treatment of serious diseases (conditions) associated with the requirements of clinics where it is recommended to disturb the patient as little as possible, for example when changing bandages, and at the same time to provide long-term stimulating influence on multiple areas of the skin. The application location of the electrodes is selected based on the response of the tissue or organ being stimulated to the exerted influence.
After the stimulation process is started, the effect of the stimulation pulses is measured based on the response of the tissues and organs of the human body. The depth of feedback, i.e. the response time of the body, is adjusted in the controlled generator by means of a second adjustment input.
The square wave generator generates a series of square wave pulses by setting the first adjustment input 11-IN of the electrical stimulator, the frequency of these square wave pulses being selected by the attending physician and specified for each stimulation channel. The duration of the generator pulse is varied by the modulator.
The output energy of the electrical stimulator is directly proportional to the duration of the pulse supplied from the output of the modulator to the input of the power amplifier and is measured in terms of the rate of flashing of the indicator and the intensity of the emitted light. The generator also determines the clock frequency of the electrical stimulator.
The controlled generator specifies the length of the sequence of stimuli and the pauses between the sequences. In order to provide a smooth rise and fall of the energy of the stimulation pulses, the output signals of the controlled generators are fed to a device for generating modulation control signals, in which device they obtain a trapezoidal shape.
The limit detector determines the amplitude of the stimulation pulses. The amplitude of the oscillation of the output circuit of the amplifier is defined by the duration of the pulses provided from the output of the modulator. The amplitude limiter of the means for generating the modulation control signal in fact adds the signals of the controlled generator and the limit detector.
As the body adapts to the stimulation influence, vibrations in the output circuit of the power amplifier of the device for generating the influencing pulses vary.
If there is a pathological change in the patient's body, the stimulation pulse at the electrode has an exponential decay with a time constant much smaller than that of a healthy body. The controlled generator generates a sequence of pulses, wherein the duration of the pause between pulses substantially exceeds the duration of the pulses. It is even possible to apply a single short stimulation pulse to the electrodes during one period.
When the stimulation pulse produces a therapeutic effect, the response of the patient's body to the stimulation effect will approach that of a healthy body or just stabilize after a certain period of time defined by both the level of the condition and the depth of feedback set at the adjustment input. This is a sufficient condition for the exposure on the stimulation channel selected by the channel coder. The adaptation is monitored in a controlled generator and in a device for analyzing the adaptation process.
The duration of the generator pulses varies in response to the feedback signal at the input of the feedback signal former. The stimulation pulse packet has a duration less than a specified duration if the condition is present in the selected point corresponding to the pair of electrodes. As the condition is eliminated, the influence on the generator on the feedback channel is reduced and the duration of the stimulation pulse packet is increased, i.e. the duration of the pulses of the time interval generator is restored.
Methods of low frequency electromagnetic therapy and apparatus for carrying out the methods are known in the art (see e.g. RU 2164424C 1). The present invention basically relies on inducing resonance in organs and systems by means of weak electromagnetic fields and thereby coordinating body functions.
The method of electromagnetic therapy comprises exposing the biologically active site and the biologically active area to a pulsed electromagnetic field having an intensity of 0.1V/sq m. The electromagnetic pulses are radio pulses, wherein the repetition rate of the packets is 0.1Hz to 100Hz, the resolution is 0.01Hz and the carrier frequency is 10kHz to 15 kHz. The device for low frequency electromagnetic therapy comprises an antenna device, a power supply, a control keypad, an LCD display, an antenna matching unit, a stabilizer whose input is connected to the power supply, a microprocessor controller connected to the control keypad by an output, an LCD display for showing the parameters of the executed therapy program, and an antenna matching unit. The microprocessor controller is configured to store up to 1000 treatment programs and form output pulses modulated at a frequency of 10kHz to 15kHz with a repetition frequency of 0.1Hz to 100 Hz.
The passive electrical property of biological tissue is characterized by an impedance whose magnitude is determined by the capacitive and effective conductivity with corresponding tissue inductance. The effective conductivity component at low frequencies is primarily due to the amount of interstitial fluid and the electrolyte composition, while at high frequencies the conductivity of the cells contributes an additional contribution. Since the resistance of cells and the capacitance of cell membranes are connected in series in an equivalent circuit of a tissue, a frequency dispersion phenomenon of the electrical conductivity of a biological tissue is observed. A bilayer lipid film with high dielectric properties and extremely low thickness is characterized by a high specific capacitance. The high charge capacity magnitude of the membrane, and hence the capacitive properties of biological tissue, is caused by the considerable polarizability of the membrane dielectric which depends on its relative permittivity. At high frequencies, the polarization mechanism turns off as relaxation time slows, and thus, as frequency is increased, the capacitance of the tissue should decrease, as is the case with increasing dielectric constant.
In the low frequency domain, the impedance of the tissue is determined primarily by the resistive properties of the tissue. The domain includes tissue with high electrical conductivity, such as neural tissue. The intermediate frequency domain includes tissue, such as a solid organ, whose electrical characteristics are determined by both resistive and capacitive characteristics. In the high frequency domain, the electrical properties of tissue are capacitive, they are for example membranes and lipids. In this frequency domain, slow polarization mechanisms can lead to significant dielectric losses in the tissue due to heating.
Thus, a living cell can be presented as a resonant circuit with a capacitance and a resistance, wherein the capacitance is determined by the free radical reaction and the antioxidant defense system, and the resistance is determined by enzymatic oxidation.
A resonant circuit has inductive properties, i.e. the ability to induce a current in another circuit or a closed conductor due to its magnetic moment. The generation of electromagnetic pulses from units to tens of hertz is a characteristic feature of the normal function of various human organs.
Not only can cells be present in the form of a resonant circuit, but higher levels of living tissue can be present in the form of a resonant circuit: tissues and organs, systems of organs and the whole body with different advantageous glucose oxidation pathways can present an induced balanced system of resonant circuits. For example, an organ such as the liver includes two glucose oxidation pathways in equal proportions, which makes the liver a key organ in the regulatory system of the body's capacitance and inductance.
Thus, the circulation system may also be presented as a cascade of closed conductors from the loop of the capillary to larger and smaller cycles. The different impedances of venous and arterial blood allow for the organs to interact with each other. The electrical properties of blood are determined by the amount of hemoglobin, oxygen, other cyclic compounds, proteins, and electrolyte components contained, as well as the blood flow rate.
Thus, the electromagnetic field in the framework of classical electrodynamics can integrate the functions of the whole body, creating and maintaining specialization of different tissues. And the circulation system is an intermediary that performs the adjustments.
Therefore, the electromagnetic vibration inherent in the tissue of the living body depends only partially on the vibration existing outside the body. Although the natural vibrations of the body are excited by the vibrations of the external electromagnetic field, they are also formed again in the body in a specific form. Each organ and each cell has its own specific spectrum of vibrations, and its own specific characteristics (shape and appearance as well as frequency) of these vibrations. Maintaining these vibrations depends on the Q factor of the resonator of the whole cell, organ, tissue or body. If the Q-factor of the resonator is damaged or lost, incoherent, insufficient abnormal electromagnetic vibrations may occur. Disease occurs in situations where the self-regulating and healing mechanisms present in the body fail to disrupt these vibrations.
When the in vivo induced field strength is significantly less than 0.1V/cm, a specific response of the human body to exposure to an artificial electromagnetic field (EMF) can only be detected at the transition to ultra-low frequencies with intensities ranging from 0.1Hz EMF to 100Hz EMF.
When comparing the effect of artificial and natural low frequencies in the range from 0.1Hz EMF to 100Hz EMF on humans, it should also be considered that exposure to artificial EMF is short, lasting much less than human life, and the effect of natural EMF is constantly generated throughout life. In this regard, it is expected that the intensity must be higher to achieve a therapeutic effect upon exposure to an artificial electromagnetic field.
Any structure that receives EMF can also emit EMF in the same frequency range, according to the principle of reciprocity of the antenna.
If the system vibration is excited by a relatively weak external force at a frequency equal to or almost equal to the natural frequency of the system, the strong vibration of the system with weakly suppressed natural vibration is called resonance.
Therefore, resonance is induced in organs and systems by means of weak electromagnetic fields, thereby coordinating the functions of the body. Since diseases of organs may have different origins, it is necessary to use different systems of the body, i.e. to use frequency sets for treatment. Thus, the program of therapeutic influence includes a set of frequencies, each operating for a predetermined time, to induce resonance in the desired organs and systems. Low frequency electromagnetic therapy induces resonance phenomena, but the energy introduced into the body is small and therefore has no overdose effect, and this is important, especially for the treatment of cancer patients.
Devices and methods for inducing apoptosis of pathological cells and tissues are known in the art (see e.g. RU 2245728C 2).
Apoptosis is a morphologically distinct form of programmed death of cells, is associated with important processes of cells and processes of variable survival of cells, and plays an important role during development, homeostasis, and in many diseases including cancer, acquired immunodeficiency syndrome, and neurodegenerative diseases. Apoptosis occurs by activating an internal cellular self-destruction program. The activation of self-destructive procedures is regulated by a number of different signals originating from both the intracellular and external environment.
The method comprises exposing pathological cells and tissues to a fixed and/or variable low frequency electromagnetic field induced at a frequency of 1Hz to 1000Hz from 1MT to 100 MT. The apparatus comprises means for generating a constant and/or low frequency alternating electromagnetic field penetrating into the workspace. The method and apparatus can influence the cell survival process of living pathological cells by magnetic field without harmful effect on healthy cells. In particular, the method includes exposure to an electromagnetic constant field (C-field) and an electromagnetic low frequency field (ELF-field) generated by the device.
The implicit concept of this method is: the CELF field influences the cell signal confirming the development of the pathological process inside the pathological cell, i.e. the signal relating to the redox potential of the free radical, thus restoring the cell survival process, i.e. stimulating apoptosis directly or indirectly by modifying the expression of the p53 gene.
The selective induction of apoptosis in pathological cells (i.e., cancer cells) by C-fields and ELF-fields, as compared to healthy cells, may be due to the altered electrical behavior of pathological cells. For these reasons, CELF fields can directly or indirectly cause signal programmed death, i.e., apoptosis, of cells in vitro and in vivo without causing adverse effects.
A sequence of magnetic C-fields with different magnetic inductions, amplitude modulation and with application of a magnetic ELF field is used. The use of a modulation field is necessary to achieve the optimal conditions for the spin singlet to triplet transition required for the recombination process with respect to the free radicals.
Preferably, the software should set the C field and the ELF field according to a total magnetic induction from 1MT to 30MT and a C/ELF field ratio in the range from 0.1 to 10, respectively, and in some special options, according to a total magnetic induction from 1MT to 10MT and a C/ELF field ratio in the range from 0.5 to 5, respectively.
The disadvantage of the therapeutic effect of the conventional method is the fact that: radiation is generated in a narrow frequency range. However, the body is a distributed self-vibrating system with many degrees of freedom, and external influences thereon in a narrow frequency range cause the body tissues to change their resonance characteristics according to the properties of the nonlinear oscillatory system in order to minimize the external influences causing the therapeutic effect to be degraded.
Theoretical analysis basis of the method
In 1954 Fermi, Pasta and ullam attempts to numerically show the transition of a nonlinear system inevitably from a single mode excited state to a state with uniformly distributed energy. The system they simulated was a chain of N particles of the same mass connected by springs with linear and non-linear terms in the interaction force.
Based on theoretical considerations, Fermi, Pasta and ullam expect that the energy initially concentrated at the low frequency mode qo will be redistributed due to nonlinear interactions between other modes, thus reproducing the transition to equilibrium. To their surprise, the results were reversed. The energy is not redistributed in any uniform way, but returns to its original mode (up to 98%) after a long period of time. Even more impressive is the fact that the time to return even decreases with increasing energy/non-linear coefficient. Refuting this later through numerical experiments was an explanation for numerical errors, and the improved accuracy and larger integration time allowed the return to 99% of the original energy to be observed.
Theoretical models of nonlinear fundamental acoustic dynamics and electrodynamics of DNA form the basis for creating a series of radio-electronic devices, soliton packet generators (FPU generators) in the form of Fermi-pata-ula recurrences, designed to generate electromagnetic waves (solitons) with a characteristic spatio-temporal structure of the FPU recurrences. The FPU reconstruction spectrum is represented by periodic transitions of the oscillating structure from an ordered state to a pseudo-chaotic state and back again. In the ordered state, the original form of the wave packet and its spatio-temporal spectrum are reproduced completely repeatedly.
An important feature of the FPU generator is the spatiotemporal structure of its field, which corresponds to the vibrational structure of the DNA molecule. The results of the mathematical simulation show that the structure of the DNA molecule corresponds to the FPU resonator.
This property allows the use of generators in experiments investigating natural vibrations in DNA products and the above-mentioned information interaction of biological systems. The initial model of such a generator was designed by one of the inventors in 1988 to 1989.
The basic configuration of the generator comprises an FPU resonator in the form of two long lines, with a non-linear element (e.g. a tunnel diode) connected to both long lines (see e.g. Longren k. "Experimental students of solionin non-linear transmission lines with dispersion", "solvents in action", moscow, Mir, 1981, pages 138 to 162).
The method is based on the use of the FPU recurrence phenomenon spectrum, which is a general fundamental characteristic of all distributed nonlinear oscillatory systems including biological systems, from which any dynamical system with many degrees of freedom has its own quasi-periodic recurrence of the fourier spectral mode dynamics of the initial perturbation of the system to its original form.
The quasi-periodic transition between the deterministic state and the quasi-chaotic state of the FPU spectrum ensures that a broadband resonance of the electromagnetic FPU reproduction spectrum of the external generator with the FPU spectrum in the body tissue is established. This results in the disruption of the autonomy of the pathological biochemical processes and thus the reduction of their energy, which ultimately leads to the elimination of the pathology from the body or in other cases the restoration of the heart rate to a normal state.
This is a fundamental difference between the mechanism of action of the FPU generator and the currently used devices.
In order to generate a broadband spectrum, a circuit for forming a reproduction of the FPU is required, which includes elements having a periodic structure. An example of such an element is a coil, since a coil is a periodic structure or a helical slow wave system. As in a canonical FPU chain with fixed ends, conditions are also required to generate standing waves. In current two-port or symmetric generators, this is provided by periodically switching the generator ports and the opposing windings of the coil. In addition, the periodic structure of the lattice of the coil material also adds harmonics to the high frequency portion of the spectrum.
The FPU spectrum "breathes". The "breathing" of the FPU spectrum is represented as pumping energy from the low frequency portion of the spectrum to the high frequency portion and back. This is the main characteristic of the FPU spectrum. Without such energy pumping, interaction of different FPU spectra is not possible.
Disclosure of Invention
It is an object of the invention to provide a device for generating a Fermi-past-ula (FPU) reconstruction spectrum as a broadband for resonant interaction with an FPU reconstruction spectrum present in body tissue.
It is another object of the present invention to provide a medical device for therapeutically affecting a lesion in a body tissue, comprising a device for generating a Fermi-past-ula (FPU) spectrum for resonant exposure to a distributed dynamic system of the body from a generator of electromagnetic field vibrations having a structure of an FPU reproduction spectrum, which provides suppression of pathological processes in the body tissue by resonant interaction with the FPU reproduction spectrum in the body tissue and increases the degree of synchronization of element dynamics in the associated dynamic system of the body.
It is a further object of the present invention to provide a method for generating Fermi-past-ullam (FPU) spectra for resonant exposure of a distributed dynamic system of a body from a generator for generating electromagnetic field vibrations of a structure having FPU recurring spectra, which suppresses pathological processes in the body tissue by resonant interaction with the FPU recurring spectra in the body tissue and increases the degree of synchronization of element dynamics in the associated dynamic system of the body.
If one of the identical molecules is in an electronically excited state, resonant interactions will typically occur between the identical molecules. The interaction is caused by the fact that: when the molecules approach each other, the excitation is transferred from one molecule to another and back. Thus, two molecules appear to be in an excited state, rather than one, and the energy level of that state is now different from the energy level of a single molecule.
Resonant interactions play a very important role in the system, causing the excitation energy to move.
This object is achieved in an apparatus for generating Fermi-past-ula (FPU) spectra, comprising:
resonator for forming the FPU electromagnetic spectrum (FPU resonator), comprising:
a two-port generator for generating vibrations, each port of the generator comprising a coil, a capacitor and a non-linearly controlled electronic component;
wherein the coils of the two-port generator have opposite windings and are connected in opposite directions, have the same number of turns and turn diameter, and the turns of one coil are alternately arranged between the turns of the other coil;
wherein the generator ports are connected to provide generation of vibration due to positive feedback between the generator ports;
a power supply section for supplying power to a connection point of the coil;
a turn-on circuit connected to the two port generator.
Advantageously, the non-linearly controlled electronic element may be an element selected from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip and a radio tube.
Preferably, the device further comprises a secondary resonator electromagnetically coupled to the coil of the FPU resonator and designed to amplify the power emitted by the FPU resonator, comprising:
two secondary oppositely connected coils with opposite windings, the coils having the same turn diameter, wherein the turns of one coil are alternately arranged between the turns of the other coil, and the terminals of the secondary coils are connected to a load to form a closed loop;
wherein the number of turns of the secondary coil is twice the number of turns of the primary coil, and the turns of the secondary coil are arranged in pairs between the turns of the primary coil, the diameter of the turns of the secondary coil being equal to the diameter of the turns of the primary coil.
Advantageously, the turns of the primary coil are arranged close to each other without gaps.
It is also advantageous that the turns of the primary coil and the secondary coil are arranged close to each other without gaps.
Preferably, the primary coil and the secondary coil are made of wire having a square or circular cross section.
Advantageously, the diameter of the primary coil is in the range 20mm to 25 mm.
Advantageously, the wire diameter of the primary coil is 2 to 2.5 times the wire diameter of the secondary coil.
Advantageously, the wire diameter of the primary coil is from 1.8mm to 2.2 mm.
Advantageously, the wire diameter of the secondary coil is from 0.8mm to 1.2 mm.
Preferably, the load is a high power diode.
Preferably, the device further comprises a two-port generator-operated light indicator coupled to one of the generator ports.
Advantageously, the operating light indicator is a light emitting diode.
According to a second embodiment of the present invention, there is provided an apparatus for generating a Fermi-past-ullam (FPU) spectrum, the apparatus comprising:
a resonator for forming a high frequency portion of the FPU electromagnetic spectrum, comprising:
two connected coils having opposite windings, the coils having the same number of turns and turn diameters, wherein the turns of one coil are alternately disposed between the turns of the other coil;
a circuit for forming a low frequency portion of the FPU electromagnetic spectrum, comprising a non-linear element and a low ohmic resistor and a supercapacitor connected in parallel and coupled to an output of the non-linear element;
wherein the other output of the non-linear element is connected to the other terminal of the one of the coils;
a circuit for adjusting the frequency of the low frequency part of the spectrum according to the heart rate of the patient, comprising a capacitor and a controlled high-ohmic resistor, one output of which is connected to the control electrode of the non-linear element and the other output of which is connected to one terminal of the second coil;
a led low frequency vibration indicator coupled to the control electrode of the non-linear element and designed to indicate short term turn-on of the resonator at a frequency close to a pulse rate of 1Hz to 1.5 Hz;
a power supply section for supplying power to the coil;
a switch installed at an output of the power supply section.
Preferably, the non-linearly controlled electronic element is an element from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip and a radio tube.
Advantageously, the device further comprises a core of dielectric material on which the coil is arranged.
Preferably, the turns of the coil are arranged close to each other without gaps.
Advantageously, the coil is made of square or round wire.
Advantageously, the diameter of the coil is in the range 20mm to 25 mm.
Preferably, the wire diameter of the coil is from 1.8mm to 2.2 mm.
In a preferred embodiment, an apparatus for generating a Fermi-past-ula (FPU) spectrum comprises:
a resonator for forming the FPU electromagnetic spectrum, comprising:
a two-port generator for generating vibrations, each port of the generator comprising a coil and a capacitor and a transistor connected in series;
wherein the coils of the two-port generator have opposite windings and are connected in opposite directions, have the same number of turns and turn diameter, and the turns of one coil are alternately arranged between the turns of the other coil, and a terminal of one of the generator coils is coupled to a collector of the transistor of one generator port, and a terminal of the other generator coil is coupled to a collector of the transistor of the other generator port;
wherein the generator ports are connected such that generation of vibration is provided due to positive feedback between the generator ports;
a power supply section for supplying power to a connection point of the coil;
two secondary oppositely connected coils with opposite windings for amplifying the power of the FPU resonator, having the same turn diameter, wherein the turns of one coil are alternately arranged between the turns of the other coil and the terminals of the secondary coils are coupled to a load to form a closed loop;
wherein the number of turns of the secondary coil is twice the number of turns of the primary coil, and the turns of the secondary coil are arranged in pairs between the turns of the primary coil to provide electromagnetic coupling, the diameter of the turns of the secondary coil being equal to the diameter of the turns of the primary coil;
a switch-on circuit comprising a resistor and a switch connected in series, wherein the output of the resistor is coupled to the collector of the transistor of one of the generator ports and the output of the switch is coupled to the base of the same transistor.
In another preferred embodiment, an apparatus for generating a Fermi-pata-ullam (FPU) spectrum comprises:
a resonator for forming a high frequency portion of the FPU electromagnetic spectrum, comprising:
two connected coils with opposite windings having the same number of turns and turn diameter, wherein the turns of one coil are alternately arranged between the turns of the other coil;
a circuit for forming a low frequency portion of the FPU electromagnetic spectrum comprising a transistor and a low ohmic resistor and a supercapacitor connected in parallel, wherein an output of the resistor is coupled to an emitter of the transistor and another output of the resistor is connected to ground, and a collector of the transistor is coupled to another terminal of said one of the coils;
a circuit for adjusting the frequency of the low frequency part of the spectrum according to the heart rate of the patient, comprising a capacitor and a controlled high-ohmic resistor, one output of the controlled high-ohmic resistor being coupled to the base of the transistor of the resonant circuit and the other output being coupled to one of the terminals of the second coil;
a led low frequency vibration indicator coupled to the base of the transistor and designed to indicate a low frequency short term turn on of the high frequency generator at a pulse rate close to 1Hz to 1.5 Hz;
a power supply section to which a terminal of one of the coils is connected;
a switch installed at an output of the power supply section.
According to a second aspect of the present invention, there is provided a medical device for therapeutically affecting different kinds of lesions in body tissue by resonant exposure of FPU reoccurring spectra in the body tissue, the device comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum according to claim 1 or 14;
a microprocessor to which the device is connected;
a temperature sensor for monitoring the temperature in the lesion area, connected to the microprocessor.
According to a second embodiment, there is provided a medical device for therapeutically affecting arrhythmias by resonance exposure of a reproduced spectrum of FPUs present in the myocardium, comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum as set forth in claim 14;
a microprocessor to which the device is connected;
a pulse sensor adapted to be mounted on the wrist of the patient and connected to the microprocessor.
According to a third embodiment, a medical device for therapeutically affecting a lesion in body tissue by resonant exposure of an FPU reoccurring spectrum in the body tissue, the device comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum as set forth in claim 14;
a microprocessor to which the device is connected;
a temperature sensor for monitoring body temperature in the lesion area, connected to the microprocessor.
According to a third aspect of the present invention, there is provided a method of therapeutically affecting a lesion in a body by electromagnetic radiation in the form of Fermi-pata-ullam (FPU) spectra for resonant exposure of FPU reoccurring spectra in body tissue, the method comprising:
generating an FPU spectrum for resonance exposure of an FPU reconstruction spectrum in body tissue using the medical device of claim 22 or 24;
securing a medical device to a patient's body in a diseased region subject to therapeutic influence;
exposing the lesion area to electromagnetic radiation of the FPU spectrum at a frequency ranging from 3Hz to 650MHz depending on the type of lesion during 5 to 30 minutes;
body temperature is monitored and whether a therapeutic effect is achieved is judged by a 0.4 ℃ to 2 ℃ rise in body temperature in the lesion area.
According to a second embodiment, a method of therapeutically affecting cardiac arrhythmias with electromagnetic radiation of a Fermi-pata-ula (FPU) spectrum for resonance exposure of a Fermi-pata-ula (FPU) recurring spectrum in the myocardium, the method comprising:
generating an FPU spectrum for resonant interaction with an FPU reconstruction spectrum in the myocardium using the medical device of claim 23;
securing a medical device to a patient in a region of the heart;
securing a pulse sensor to a wrist of a patient;
exposing a region of the heart to electromagnetic radiation of the FPU spectrum during 5 to 30 minutes at an exposure frequency in the range of 3Hz to 650 MHz;
setting the resistance of the controlled high-ohmic resistor according to the required pulse rate;
monitoring pulses from a blinking frequency of the led low frequency vibration indicator;
meanwhile, the electrocardiogram of the heart is monitored, and whether the therapeutic effect is achieved or not is judged according to the electrocardiogram of the heart.
According to the theory of resonance interaction between Fermi-pata-ullam reoccurrences, the FPU reoccurrence energy of healthy tissue is increased due to a decrease in FPU reoccurrence energy of the diseased tissue, which thus significantly decreases its intensity or disappears completely.
The present device provides forced synchronization of the characteristics of the electromagnetic vibrations generated by the generator and normal tissue vibrations with natural vibrations in the body tissue. Due to the fact that the lesion in the tissue has oscillation parameters different from those of normal tissue, synchronously, the energy of the pathological vibrations in the body tissue is reduced and this causes a therapeutic effect.
Drawings
The invention is further explained by the description of preferred embodiments with reference to the drawings, in which:
FIG. 1 illustrates a circuit of an apparatus for generating an FPU spectrum for resonant interaction with an FPU reproduction spectrum in body tissue according to the present invention;
figure 2 schematically shows the turns of the coils of the primary and secondary resonators;
FIG. 3 shows a circuit of an apparatus for generating a FPU spectrum, the circuit including a secondary resonator for amplifying the FPU electromagnetic spectrum of a primary resonator;
figure 4 shows the arrangement of turns of the coil of the secondary resonator between turns of the coil of the primary resonator;
FIG. 5 shows a circuit of a second embodiment of an apparatus for generating a FPU spectrum according to the present invention;
FIG. 6 illustrates a medical device for generating an FPU spectrum for resonant interaction with an FPU reconstruction spectrum in body tissue in accordance with the present invention;
fig. 7 shows a second embodiment of a medical device for generating an FPU spectrum for resonant interaction with an FPU reconstruction spectrum in body tissue according to the present invention.
Detailed Description
The device 1 (fig. 1) for generating Fermi-past-ula (FPU) spectrum comprises a resonator 2(FPU resonator) for forming the FPU electromagnetic spectrum, the resonator comprising a two-port generator for generating vibrations, each port 3, 4 of which comprises a coil, a capacitor and a non-linearly controlled electronic component, in particular, the port 3 comprises a coil 5, a capacitor 6 and a non-linearly controlled electronic component 7, and the port 4 comprises a coil 8, a capacitor 9 and a non-linearly controlled electronic component 10.
The non-linearity controlled electronic component 7 or 9 may be a component selected from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip and a radio tube. The preferred embodiment uses transistors.
As schematically shown in fig. 2, the coils 5 and 8 of the two-port generator have opposite windings and are connected in opposite directions; they have the same number of turns and turn diameters. In an embodiment, the coils 5 and 8 have six turns, but may be eight, or ten or another number of turns. In the described configuration, the turns of one coil 5 are arranged alternately between the turns of the other coil 8.
The ports 3 and 4 of the two-port generator are connected so as to ensure that the generator generates vibrations due to positive feedback between the ports 3 and 4.
The device 1 comprises a power supply 11, for example a 20V DC voltage power supply, which supplies power to the connection point a of the coils 5 and 8.
In the preferred embodiment described, the terminal of one coil 5 is connected to the collector of the transistor 10 of one port 3 of the generator, while the terminal of the other coil 8 is connected to the collector of the transistor 7 of the other port 4.
The device 1 further comprises a trigger circuit 12, which in this embodiment comprises a resistor 13 and a switch 14 connected in series; the output of resistor 13 is connected to the collector of transistor 7 of generator port 3 and the output of switch 14 is connected to the base of the same transistor 7.
The device 1 preferably comprises a secondary resonator 15 (fig. 3) which is electromagnetically coupled to the coil of the FPU resonator 1 and is adapted to amplify the power of the primary FPU resonator.
The secondary resonator 15 is formed, for example, by two secondary oppositely connected coils 16, 17 with opposite windings, which have the same turn diameter, wherein the turns of one coil 16 are alternately arranged between the turns of the other coil 17. The terminals of the secondary coils 16, 17 are connected to a load 18 to form a closed loop.
The number of turns of the secondary coils 16 and 17 is twice the number of turns of the primary coils 5 and 8, and the turns of the secondary coils 16 and 17 are arranged in pairs between the turns of the primary coils 5 and 8, and the diameter of the turns of the secondary coils 16 and 17 is equal to the diameter of the turns of the primary coils 5 and 8.
The generator ports 3, 4 switch the direction of the current in the resonators 1 and 15.
The turns of the primary coils 5 and 8 are arranged close to each other without gaps. If the secondary resonator 15 is available, the turns of the primary coil 5, the secondary coil 16, the secondary coil 17 and the primary coil 8 are arranged close to each other without gaps (fig. 4).
The coils 5, 8, 16, 17 are made of square or round wire.
Preferably, the diameter of the coils 5 and 8 of the primary resonator 1 is in the range of 20mm to 25 mm.
The wire diameter of the coils 5 and 8 is 2 to 2.5 times the wire diameter of the secondary coils 16 and 17; in this embodiment, the wire diameter of the primary coils 5 and 8 is in the range of 1.8mm to 2.2mm, while the wire diameter of the secondary coils 16, 17 is from 0.8mm to 1.2 mm.
The load 18 of the secondary resonator 15 is a high power diode, for example with a direct current of 5A and higher. The diode, as a non-linear element, affects the frequency spectrum of the generator vibrations; especially due to the non-linearity of the PN junction, additional harmonics, i.e., an increased set of harmonics and a rich spectrum, may occur.
The device 1 further comprises a two port generator operating light indicator 19 coupled to one port 3 of the generator; the light indicator 19 is a light emitting diode (led).
According to a second embodiment, a device 20 (fig. 5) for generating a Fermi-past-ula (FPU) spectrum comprises a resonator 21(FPU resonator) for generating a high frequency part of the FPU electromagnetic spectrum, the resonator comprising two oppositely or uniformly connected coils 22, 23 with opposite windings, said coils having the same number of turns and turn diameters, wherein the turns of one coil 22 are alternately arranged between the turns of the other coil 23.
The apparatus 20 further comprises a circuit 24 for generating a low frequency portion of the FPU electromagnetic spectrum, the circuit comprising a non-linear element 25 and a parallel connected low-ohmic resistor 26 and supercapacitor 27 both connected to the output of the non-linear element 25.
In the described embodiment, the non-linearly controlled electronic element 25 may be an element selected from the group consisting of a bipolar transistor, a thyristor, a field transistor, a chip, and a radio tube. In a preferred embodiment, the element is a transistor. The other output of the non-linear element 25 is coupled to the other terminal of said one of the coils 23.
The apparatus 20 further comprises a circuit 28 for adjusting the frequency of the low frequency part of the spectrum in accordance with the heart rate of the patient. The circuit 28 comprises a capacitor 29 and a controlled high-ohmic resistor 30, the output of which is coupled to the control electrode of the non-linear element 25, while the other output is connected to one of the terminals of the second coil 22.
The device 20 further comprises a led low frequency vibration indicator 31 coupled to the control electrode of the non-linear element 25, in this case to the transistor base. The indicator 31 is intended to indicate a short-term switching on of the resonator 21, which operates at a frequency close to the pulse rate of 1Hz to 1.5 Hz.
The device 20 in the described embodiment further comprises a power supply 32 for supplying power to the coils 22 and 23 and a switch 33 mounted at an output of the power supply 32.
The apparatus 20 also includes a core 34 of dielectric material on which the coils 22 and 23 are mounted. The turns of the coils 22 and 23 are arranged close to each other without gaps.
Preferably, the coils 22 and 23 are made of square or round wire. The diameter of the coils 22 and 23 is preferably 20mm to 25mm, and the wire diameter of the coils is preferably from 1.8mm to 2.2 mm.
According to a second aspect of the present invention, there is provided a medical device 35 (fig. 6) for therapeutically influencing a lesion in body tissue by resonant exposure of an FPU reoccurring spectrum in the body tissue, the medical device comprising: a housing 36 of non-magnetic material for placement on the body of a patient. The housing 36 encloses in its cavity the coils 5, 8, 16, 17 of the FPU resonator 2 of the device 1 for generating the Fermi-past-ula (FPU) spectrum and a microprocessor 37 to which the switch 14 of the trigger circuit of the device 1 is connected.
The two port generator is housed in a separate housing 38. On the housing 38, there is provided a device operating light indicator 19 and a switch 14 of the trigger circuit 12, both electrically connected to the microprocessor 37. The coils 5 and 8 are connected to the power supply 11 with wires 39 and 40.
In one set, the medical device 35 further comprises a temperature sensor 41 coupled to the microprocessor 37 for monitoring the temperature in the diseased region.
The housing 37 comprises means 42 for securing the device to the body of the patient.
According to a second embodiment, a medical device 43 (fig. 7) for therapeutic influencing of cardiac arrhythmias by resonance exposure of an FPU reconstruction spectrum in the myocardium is provided. The medical device comprises a housing 44 of non-magnetic material for placement on the body of a patient. The housing 44 encloses in its cavity the coils 22, 23 of the resonator 21 and a microprocessor 45 to which the switch 33 of the device 20 for generating the Fermi-past-ullam (FPU) spectrum is coupled.
The medical device 43 further comprises an additional housing 46 which houses the circuitry 24 for forming the low frequency part of the FPU electromagnetic spectrum and the circuitry 28 for adjusting the frequency of the low frequency part of the spectrum in accordance with the heart rate of the patient. The front panel of the housing 46 includes a low frequency vibrating led indicator 31 and a switch 33.
In one set, the medical device 42 includes a pulse sensor 47 to be secured to the wrist of the patient, coupled to the microprocessor 45.
Fig. 7 also shows the power supply 32 connected to the coils 22, 23 of the resonator 20 by a wire 48. The housing 44 comprises means 49 for securing the device on the body of a patient in the region of the heart.
A second possible embodiment (not shown) of a medical device 43 for therapeutically affecting a lesion in body tissue by resonant exposure of FPU reoccurring spectra in the body tissue comprises: a housing of non-magnetic material for placement on the body of a patient, which housing encloses in its cavity the coils 22 and 23 of the device 20 for generating the Fermi-pata-ula (FPU) spectrum and the microprocessor to which the device 20 is connected; the medical device set includes a temperature sensor connected to the microprocessor for monitoring body temperature in the lesion area.
In all embodiments, the microprocessor may be used to turn the medical device on or off, for example, when a predetermined therapeutic effect is achieved.
The medical device operates in the following manner.
When the start button is pressed, operation of the device is initiated by providing a positive voltage to the base of the transistor. During operation, the led should be permanently lit to indicate that there is vibration in the generator, since even with power on, the generator may be inoperable for various reasons.
The time for establishing the operation mode of the medical device at switch-on should not exceed 1 min. The establishment of the operating mode is accompanied by a light on indication.
The medical device is intended for use in hospitals, specialist clinics and hospitals, medical centers and at home under normal climatic conditions, which are characterized by the following values: ambient temperature from 15 ℃ to 25 ℃; relative humidity from 45% to 75%; the atmospheric pressure is from 97.3kPa to 105.3kPa (730mmHg to 790 mmHg).
A toggle switch for switching the operating mode may be provided on the housing, as the generator may have two operating modes: the labels are stronger and weaker high/low.
The operating principle is based on the influence of the FPU spectrum on various pathological processes occurring in the myocardium. Due to the quasi-periodic transitions between the regular and chaotic vibrations of the generator, nonlinear FPU resonances with their own oscillation processes occur in the myocardium. The duration of a process is 5 minutes to 20 minutes, depending on the individual recommendations.
A method for therapeutically influencing a lesion in a body by electromagnetic radiation of a Fermi-pata-ullam (FPU) spectrum for resonant exposure of an FPU reproduction spectrum in body tissue is accomplished in the following manner.
A medical device 35 for generating an FPU spectrum for resonance exposure of an FPU reconstruction spectrum in body tissue is fixed on the patient body in the lesion region subject to therapeutic influence.
The medical device is switched on and the lesion area is exposed to electromagnetic radiation of the FPU spectrum at a frequency in the range from 3Hz to 650MHz for 5 to 30 minutes depending on the type of lesion.
Simultaneously, monitoring the body temperature, and determining that a therapeutic effect is achieved according to the increase of the body temperature in the lesion area by 0.4 ℃ to 2 ℃; for this purpose, the body temperature in the lesion area is permanently measured by the temperature sensor 39. When the body temperature in the lesion area rises by 0.4 ℃ to 2 ℃, it is determined that a therapeutic effect is achieved. The temperature is constantly increasing, but in healthy people the body temperature does not rise more than 0.1 ℃ to 0.2 ℃, whereas if there are inflammatory lesions, the temperature under irradiation rises 0.4 ℃ to 2 ℃.
This period of time typically lasts from 10 minutes to 20 minutes. To achieve a therapeutic effect, 5 to 6 exposure periods were completed.
It is recommended that these processes be performed at the same time intervals during the period from 4 pm to 10 pm, but these processes may be performed in the morning and afternoon. The course of treatment lasts 3 to 6 days, depending on the recommendations of the physician and the severity of the disease.
The therapeutic effect has occurred after a first period of time.
As mentioned above, healthy tissue and tissue with a disorder, such as tissue with inflammation, have different Fermi-Pasta-ula (FPU) radiation spectra, as evidenced by analysis of their electromagnetic radiation spectra. Furthermore, the interaction of the radiation spectrum of these healthy and diseased tissues with external electromagnetic radiation from the Fermi-Pasta-ullam (FPU) spectrum of the medical device occurs in different ways. Specific exposure characteristics are selected and suggested by experimentation, however, specific exposure characteristics may be modified according to individual characteristics of a particular patient.
The FPU spectral energy from the medical device is transferred to the FPU spectral energy of healthy tissue and tissue with a disorder. It should be noted that statistically, the mass of the tissue with the disorder is no more than 10%, i.e. it is significantly less, compared to the mass of healthy tissue. Thus, healthy tissue captures many times more FPU spectral energy when entering resonance than tissue with the disorder captures FPU spectral energy when entering resonance.
The FPU spectral energy of healthy tissue increases. It can be said that the FPU spectral energy of healthy tissue suppresses the FPU spectral energy of diseased tissue. Thus, the FPU spectral energy of the tissue with the disorder is reduced.
In one example, a method for therapeutically affecting arrhythmias via electromagnetic radiation of a Fermi-pata-ula (FPU) spectrum for resonance exposure of a Fermi-pata-ula (FPU) recurring spectrum in the myocardium is accomplished in the following manner.
The medical device 43 (fig. 7) is secured to the patient's body in the region of the heart and the pulse sensor 47 is secured to the wrist of the patient.
The heart region is exposed to electromagnetic radiation of the FPU spectrum during 5 to 30 minutes.
The resistance of the controlled high ohmic resistor 30 is set according to the required pulse rate and the pulse rate is monitored from the flashing frequency of the led low frequency vibration indicator 31. The pulse rate is required to achieve resonant exposure of the heart; the allowable range is within the medical range of heart rates.
The electrocardiogram of the heart is continuously monitored to determine therefrom the achievement of the therapeutic effect.
Medical devices are used to treat arrhythmias of diverse origins. The device provides forced synchronization of the oscillation process in the myocardium or other tissues of the body in a continuous mode over a predetermined time of therapeutic influence.
The medical device relates to a therapeutic device preferably operating at a frequency from 3Hz to 650 MHz.
The power consumed by the generator must not be greater than 15 watts.
The use indications are:
various inflammatory processes, including necrotizing inflammation after myocardial infarction, lymph node infiltration (tonsillitis), sinusitis, periodontitis, and the like. Abnormal heart rhythm (arrhythmia);
radiculitis, sciatica, lumbago, intercostal neuralgia;
post-traumatic inflammation after injury, sprain and dislocation;
-effective in joint and rheumatalgia, arthritis;
it is effective for treating hemorrhoid and prostatitis.
The exposure time is typically 20 minutes to 25 minutes. The treatment period is 3 to 6 days. The most efficient time for using the generator is from 4 pm to 10 pm.
Example 1 Using medical device
Patient d, 58 years old, had persistent arrhythmia. The loss of pulses is determined on average once every three strokes. The FPU generator was placed on the sternum and within five minutes after the initial exposure, the arrhythmia was dramatically reduced and completely disappeared after ten minutes. 5 therapeutic sessions were performed with the FPU generator at 10 min exposure. Within a few months after treatment, observations did not show arrhythmia in the patient. Thus, the FPU generator is effective in eliminating arrhythmias.
Example 2 Using medical device
Patient a, 60 years old. Onset of sciatica. Acute pain in the lumbar region impedes patient mobility. The FPU generator is placed over the lumbar region. The exposure time was 35 minutes. During exposure, the pain almost disappeared and the patient was able to move freely. Four time periods were performed at an exposure time of 35 minutes, after which the patient was returned to work. Thus, the FPU generator is effective in eliminating the consequences of an sciatica episode.
INDUSTRIAL APPLICABILITY
Medical devices and methods for therapeutic effects on lesions in body tissue by electromagnetic radiation having a structure of Fermi-pata-ullam (FPU) recurring spectra can be used for treating cardiac arrhythmias and inflammatory processes in vivo, as well as for coordinating the function of organs and enhancing body defenses.
The claims (modification according to treaty clause 19)
1. An apparatus for generating a Fermi-Pasta-ula (FPU) spectrum, comprising:
a resonator for forming the FPU electromagnetic spectrum (FPU resonator), the resonator comprising:
a two-port generator for generating vibrations, each port of the generator comprising a coil, a capacitor and a non-linearly controlled electronic component;
wherein the coils of the two-port generator have opposite windings and are connected in opposite directions, have the same number of turns and turn diameter, and the turns of one coil are alternately arranged between the turns of the other coil;
wherein the generator ports are connected to provide generation of vibration due to positive feedback between the generator ports;
a power supply section for supplying power to a connection point of the coil;
a flip-flop circuit connected to the two-port generator.
2. The apparatus of claim 1, wherein the non-linearly controlled electronic element is an element selected from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip, and a radio tube.
3. The apparatus of claim 1, further comprising a secondary resonator electromagnetically coupled to the coil of the FPU resonator and designed to amplify power of the FPU resonator, the secondary resonator comprising:
two secondary reverse-connected coils having opposite windings, the two secondary reverse-connected coils having the same turn diameter, wherein turns of one coil are alternately disposed between turns of the other coil, and terminals of the secondary coils are connected to a load to form a closed loop;
wherein the number of turns of the secondary coil is twice the number of turns of the coil of the FPU resonator, and the turns of the secondary coil are disposed in pairs between the turns of the coil of the FPU resonator, and the diameter of the turns of the secondary coil is equal to the diameter of the turns of the coil of the FPU resonator.
4. The apparatus of claim 1 wherein the turns of the coil of the FPU resonator are disposed close to each other without gaps.
5. The apparatus of claim 3, wherein the turns of the coil and the secondary coil of the FPU resonator are disposed close to each other without gaps.
6. The apparatus of claim 1 or 3, wherein the coil of the FPU resonator and the secondary coil are made of square or round wires.
7. The apparatus of claim 1 wherein the coils of the FPU resonator have a diameter in the range of 20mm to 25 mm.
8. The apparatus of claim 3, wherein the wire diameter of the coil of the FPU resonator is 2 to 2.5 times the wire diameter of the secondary coil.
9. The apparatus of claim 1 wherein the wire diameter of the coil of the FPU resonator is from 1.8mm to 2.2 mm.
10. The apparatus of claim 3, wherein the wire diameter of the secondary coil is from 0.8mm to 1.2 mm.
11. The apparatus of claim 3, wherein the load is a high power diode.
12. The apparatus of claim 1, further comprising a two-port generator-operated light indicator coupled to one of the generator ports.
13. The apparatus of claim 12, wherein the operating light indicator is a light emitting diode.
14. An apparatus for generating a Fermi-Pasta-ula (FPU) spectrum, comprising:
a resonator for forming a high frequency portion of the FPU electromagnetic spectrum, the resonator comprising:
two connected coils having opposite windings, the two connected coils having the same number of turns and turn diameters, wherein the turns of one coil are alternately disposed between the turns of the other coil;
a circuit for forming a low frequency portion of the FPU electromagnetic spectrum, the circuit comprising a non-linear element and a low-ohmic resistor and a supercapacitor connected in parallel and coupled to an output of the non-linear element;
wherein the other output of the non-linear element is connected to the other terminal of one of the coils;
a circuit for adjusting the frequency of the low frequency part of the spectrum in accordance with the heart rate of the patient, the circuit comprising a capacitor and a controlled high-ohmic resistor, one output of the controlled high-ohmic resistor being connected to the control electrode of the non-linear element and the other output being connected to one terminal of a second coil;
a led low frequency vibration indicator coupled to the control electrode of the nonlinear element and designed to instruct short term switching of the resonator at a frequency close to a pulse rate of 1Hz to 1.5 Hz;
a power supply section for supplying power to the coil;
a switch mounted at an output of the power supply.
15. The apparatus of claim 14, wherein the non-linearly controlled electronic element is an element from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip, and a radio tube.
16. The apparatus of claim 14, further comprising a core of dielectric material on which the coil is disposed.
17. The apparatus of claim 14, wherein the turns of the coil are disposed proximate to each other without gaps.
18. The apparatus of claim 14, wherein the coil is made of square or round wire.
19. The apparatus of claim 14, wherein the coil has a diameter in the range of 20mm to 25 mm.
20. The apparatus of claim 14, wherein the wire diameter of the coil is from 1.8mm to 2.2 mm.
21. An apparatus for generating a Fermi-Pasta-ula (FPU) spectrum, comprising:
a resonator for forming the FPU electromagnetic spectrum, the resonator comprising:
a two-port generator for generating vibrations, each port of the generator comprising a capacitor and a transistor connected in series and a coil;
wherein the coils of the two-port generator have opposite windings and are connected in opposite directions, have the same number of turns and turn diameter, and the turns of one coil are alternately arranged between the turns of the other coil, and a terminal of one of the generator coils is coupled to a collector of the transistor of one generator port and a terminal of the other generator coil is coupled to a collector of the transistor of the other generator port;
wherein the generator ports are connected such that generation of vibration is provided due to positive feedback between the generator ports;
a power supply section for supplying power to a connection point of the coil;
two secondary oppositely connected coils with opposite windings for amplifying the power of the FPU resonator, the two secondary oppositely connected coils having the same turn diameter, wherein the turns of one coil are alternately arranged between the turns of the other coil and the terminals of the secondary coils are coupled to a load to form a closed loop;
wherein the number of turns of the secondary coil is twice the number of turns of the coil of the FPU resonator and the turns of the secondary coil are arranged in pairs between the turns of the coil of the FPU resonator to provide electromagnetic coupling, the diameter of the turns of the secondary coil being equal to the diameter of the turns of the coil of the FPU resonator;
a trigger circuit comprising a resistor and a switch connected in series, wherein an output of the resistor is coupled to a collector of the transistor of one of the generator ports and an output of the switch is coupled to a base of the same transistor.
22. An apparatus for generating a Fermi-Pasta-ula (FPU) spectrum, comprising:
a resonator for forming a high frequency portion of the FPU electromagnetic spectrum, the resonator comprising:
two connected coils having opposite windings, the two connected coils having the same number of turns and turn diameters, wherein the turns of one coil are alternately disposed between the turns of the other coil;
a circuit for forming a low frequency portion of the FPU electromagnetic spectrum, the circuit comprising a transistor and a low ohmic resistor and a supercapacitor connected in parallel, wherein an output of the resistor is coupled to an emitter of the transistor and another output of the resistor is connected to ground, and a collector of the transistor is coupled to another terminal of one of the coils;
a circuit for adjusting the frequency of the low frequency part of the spectrum according to the heart rate of the patient, comprising a capacitor and a controlled high-ohmic resistor, one output of which is coupled to the base of the transistor of the resonant circuit and the other output is coupled to one of the terminals of the second coil;
a led low frequency vibration indicator coupled to the base of the transistor and designed to indicate short term turn on of the generator at a frequency close to a pulse rate of 1Hz to 1.5 Hz;
a power supply section to which a terminal of one of the coils is connected;
a switch mounted at an output of the power supply.
23. A medical device for therapeutically affecting a lesion in body tissue by resonant exposure of FPU reoccurring spectra in the body tissue, comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum according to claim 1 or 14;
a microprocessor to which the device is connected;
a temperature sensor for monitoring temperature in the diseased region, the temperature sensor being connected to the microprocessor.
24. A medical device for therapeutically affecting arrhythmias by resonance exposure of FPU reoccurring spectra in the myocardium, comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum as set forth in claim 14;
a microprocessor to which the device is connected;
a pulse sensor adapted to be mounted on the wrist of the patient and connected to the microprocessor.
25. A medical device for therapeutically affecting a lesion in body tissue by resonant exposure of FPU reoccurring spectra in the body tissue, comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum as set forth in claim 14;
a microprocessor to which the device is connected;
a temperature sensor for monitoring body temperature in the lesion, the temperature sensor connected to the microprocessor.
26. A method of therapeutically affecting a lesion in a body by electromagnetic radiation of a Fermi-pata-ula (FPU) spectrum for resonant exposure of a Fermi-pata-ula (FPU) recurring spectrum in body tissue, comprising:
generating the FPU spectrum for resonance exposure of the FPU reoccurring spectrum in the body tissue using the medical device of claim 23 or 25;
securing the medical device on the body of the patient in the diseased region subject to therapeutic influence;
exposing the lesion area to electromagnetic radiation of the FPU spectrum at a frequency ranging from 3Hz to 650MHz depending on the type of lesion during 5 to 30 minutes;
monitoring body temperature and determining whether a therapeutic effect is achieved based on a 0.4 ℃ to 2 ℃ increase in the body temperature in the lesion.
27. A method of therapeutically affecting cardiac arrhythmias via electromagnetic radiation of a Fermi-pata-ula (FPU) spectrum for resonance exposure of a Fermi-pata-ula (FPU) recurring spectrum in the myocardium, comprising:
generating the FPU spectrum for resonant interaction with the FPU reconstruction spectrum in the myocardium using the medical device of claim 24;
securing the medical device to a patient in a region of the heart;
securing a pulse sensor to a wrist of a patient;
exposing the cardiac region to electromagnetic radiation of the FPU spectrum over a period of 5 to 30 minutes at an exposure frequency in the range of 3Hz to 650 MHz;
setting the resistance of the controlled high-ohmic resistor according to a desired pulse rate;
monitoring pulses from a blinking frequency of the led low frequency vibration indicator;
while monitoring the electrocardiogram of the heart and determining from the electrocardiogram of the heart whether a therapeutic effect has been achieved.
Claims (27)
1. An apparatus for generating a Fermi-Pasta-ullam (FPU) spectrum, the apparatus comprising:
resonator for forming the FPU electromagnetic spectrum (FPU resonator), comprising:
a two-port generator for generating vibrations, each port of the generator comprising a coil, a capacitor and a non-linearly controlled electronic component;
wherein the coils of the two-port generator have opposite windings and are connected in opposite directions, have the same number of turns and turn diameters, and the turns of the one coil are alternately arranged between the turns of the other coil;
wherein the generator ports are connected to provide generation of vibration due to positive feedback between the generator ports;
a power supply section for supplying power to a connection point of the coil;
a flip-flop circuit connected to the two-port generator.
2. The apparatus of claim 1, wherein the non-linearly controlled electronic element is an element selected from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip, and a radio tube.
3. The apparatus of claim 1, further comprising a secondary resonator electromagnetically coupled to the coil of the FPU resonator and designed to amplify power of the FPU resonator, the secondary resonator comprising:
two secondary reverse-connected coils having opposite windings, the two secondary reverse-connected coils having the same turn diameter, wherein turns of the one coil are alternately disposed between turns of the other coil, and terminals of the secondary coils are connected to a load to form a closed loop;
wherein the number of turns of the secondary coil is twice the number of turns of the primary coil, and the turns of the secondary coil are arranged in pairs between the turns of the primary coil, the diameter of the turns of the secondary coil being equal to the diameter of the turns of the primary coil.
4. The apparatus of claim 1, wherein the turns of the primary coil are disposed close to each other without gaps.
5. The apparatus of claim 3, wherein the turns of the primary coil and the secondary coil are disposed close to each other without gaps.
6. The apparatus of claim 1 or 3, wherein the primary coil and the secondary coil are made of square or round wire.
7. The apparatus of claim 1, wherein the diameter of the primary coil is in the range of 20mm to 25 mm.
8. The apparatus of claim 3, wherein the wire diameter of the primary coil is 2 to 2.5 times the wire diameter of the secondary coil.
9. The apparatus of claim 1, wherein the wire diameter of the primary coil is from 1.8mm to 2.2 mm.
10. The apparatus of claim 3, wherein the wire diameter of the secondary coil is from 0.8mm to 1.2 mm.
11. The apparatus of claim 3, wherein the load is a high power diode.
12. The apparatus of claim 1, further comprising a two-port generator-operated light indicator coupled to one of the generator ports.
13. The apparatus of claim 12, wherein the operating light indicator is a light emitting diode.
14. An apparatus for generating a Fermi-Pasta-ullam (FPU) spectrum, the apparatus comprising:
a resonator for forming a high frequency portion of the FPU electromagnetic spectrum, the resonator comprising:
two connected coils having opposite windings, the two connected coils having the same number of turns and turn diameters, wherein the turns of one coil are alternately disposed between the turns of the other coil;
a circuit for forming a low frequency portion of the FPU electromagnetic spectrum, the circuit comprising a non-linear element and a low-ohmic resistor and a supercapacitor connected in parallel and coupled to an output of the non-linear element;
wherein the other output of the non-linear element is connected to the other terminal of one of the coils;
a circuit for adjusting the frequency of the low frequency part of the spectrum in accordance with the heart rate of the patient, the circuit comprising a capacitor and a controlled high-ohmic resistor, one output of the controlled resistor being connected to the control electrode of the non-linear element and the other output of the controlled resistor being connected to one terminal of a second coil;
a led low frequency vibration indicator coupled to the control electrode of the nonlinear element and designed to indicate short term switching on of the resonator at a frequency close to a pulse rate of 1Hz to 1.5 Hz;
a power supply section for supplying power to the coil;
a switch mounted at an output of the power supply.
15. The apparatus of claim 14, wherein the non-linearly controlled electronic element is an element from the group consisting of a bipolar transistor, a thyristor, a field effect transistor, a chip, and a radio tube.
16. The apparatus of claim 14, further comprising a core of dielectric material on which the coil is disposed.
17. The apparatus of claim 14, wherein the turns of the coil are disposed proximate to each other without gaps.
18. The apparatus of claim 14, wherein the coil is made of square or round wire.
19. The apparatus of claim 14, wherein the coil has a diameter in the range of 20mm to 25 mm.
20. The apparatus of claim 14, wherein the wire diameter of the coil is from 1.8mm to 2.2 mm.
21. An apparatus for generating a Fermi-Pasta-ullam (FPU) spectrum, the apparatus comprising:
a resonator for forming the FPU electromagnetic spectrum, the resonator comprising:
a two-port generator for generating vibrations, each port of the generator comprising a capacitor and a transistor connected in series and a coil;
wherein the coils of the two-port generator have opposite windings and are connected in opposite directions, have the same number of turns and turn diameter, and the turns of the one coil are alternately arranged between the turns of the other coil, and a terminal of one of the generator coils is coupled to a collector of the transistor of one generator port and a terminal of the other generator coil is coupled to a collector of the transistor of the other generator port;
wherein the generator ports are connected such that generation of vibration is provided due to positive feedback between the generator ports;
a power supply section for supplying power to a connection point of the coil;
two secondary oppositely connected coils with opposite windings for amplifying the power of the FPU resonator, the two secondary oppositely connected coils having the same turn diameter, wherein the turns of one coil are alternately arranged between the turns of the other coil and the terminals of the secondary coils are coupled to a load to form a closed loop;
wherein the number of turns of the secondary coil is twice the number of turns of the primary coil, and the turns of the secondary coil are arranged in pairs between the turns of the primary coil to provide electromagnetic coupling, the diameter of the turns of the secondary coil being equal to the diameter of the turns of the primary coil;
a switch-on circuit comprising a resistor and a switch connected in series, wherein an output of the resistor is coupled to a collector of the transistor of one of the generator ports and an output of the switch is coupled to a base of the same transistor.
22. An apparatus for generating a Fermi-Pasta-ullam (FPU) spectrum, the apparatus comprising:
a resonator for forming a high frequency portion of the FPU electromagnetic spectrum, the resonator comprising:
two connected coils having opposite windings, the two connected coils having the same number of turns and turn diameters, wherein the turns of one coil are alternately disposed between the turns of the other coil;
a circuit for forming a low frequency portion of the FPU electromagnetic spectrum, the circuit comprising a transistor and a low ohmic resistor and a supercapacitor connected in parallel, wherein an output of the resistor is coupled to an emitter of the transistor and another output of the resistor is connected to ground, and a collector of the transistor is coupled to another terminal of one of the coils;
a circuit for adjusting the frequency of the low frequency part of the spectrum in accordance with the heart rate of the patient, the circuit comprising a capacitor and a controlled high-ohmic resistor, one output of the resistor being coupled to the base of the transistor of the resonant circuit and the other output of the resistor being coupled to one of the terminals of the second coil;
a led low frequency vibration indicator coupled to the base of the transistor and designed to indicate short term turn on of the generator at a frequency close to a pulse rate of 1Hz to 1.5 Hz;
a power supply section to which a terminal of one of the coils is connected;
a switch mounted at an output of the power supply.
23. A medical device for therapeutically affecting a lesion in body tissue by resonant exposure of FPU reoccurring spectra in the body tissue, the device comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum according to claim 1 or 14;
a microprocessor to which the device is connected;
a temperature sensor for monitoring temperature in the diseased region, the temperature sensor being connected to the microprocessor.
24. A medical device for therapeutically affecting arrhythmias by resonance exposure of an FPU reoccurring spectrum in the myocardium, the device comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum as set forth in claim 14;
a microprocessor to which the device is connected;
a pulse sensor adapted to be mounted on the wrist of the patient and connected to the microprocessor.
25. A medical device for therapeutically affecting a lesion in body tissue by resonant exposure of FPU reoccurring spectra in the body tissue, the device comprising:
a housing of non-magnetic material for placement on a patient's body, the housing enclosing in its cavity:
the apparatus for generating a Fermi-pata-ula (FPU) spectrum as set forth in claim 14;
a microprocessor to which the device is connected;
a temperature sensor for monitoring body temperature in the lesion area and connected to the microprocessor.
26. A method of therapeutically affecting a lesion in a body by electromagnetic radiation of a Fermi-pata-ula (FPU) spectrum for resonant exposure of a Fermi-pata-ula (FPU) recurring spectrum in body tissue, the method comprising:
generating the FPU spectrum for resonance exposure of the FPU reoccurring spectrum in the body tissue using the medical device of claim 23 or 25;
securing the medical device on the body of the patient in the diseased region subject to therapeutic influence;
exposing the lesion area to electromagnetic radiation of the FPU spectrum at a frequency ranging from 3Hz to 650MHz depending on the type of lesion during 5 to 30 minutes;
monitoring body temperature and determining whether a therapeutic effect is achieved based on a 0.4 ℃ to 2 ℃ increase in the body temperature in the lesion.
27. A method of therapeutically affecting cardiac arrhythmias via electromagnetic radiation of a Fermi-pata-ula (FPU) spectrum used for resonance exposure of a Fermi-pata-ula (FPU) recurring spectrum in the myocardium, the method comprising:
generating the FPU spectrum for resonant interaction with the FPU reconstruction spectrum in the myocardium using the medical device of claim 24;
securing the medical device to a patient in a region of the heart;
securing a pulse sensor to a wrist of a patient;
exposing the cardiac region to electromagnetic radiation of the FPU spectrum over a period of 5 to 30 minutes at an exposure frequency in the range of 3Hz to 650 MHz;
setting the resistance of the controlled high-ohmic resistor according to a desired pulse rate;
monitoring pulses from a blinking frequency of the led low frequency vibration indicator;
while monitoring the electrocardiogram of the heart and determining from the electrocardiogram of the heart whether a therapeutic effect has been achieved.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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PCT/RU2017/000737 WO2019070144A1 (en) | 2017-10-03 | 2017-10-03 | Wideband electromagnetic resonator for therapeutic treatment of pathological foci in tissues of an organism, medical device for therapeutic treatment and method of therapeutic treatment |
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CN111182942A true CN111182942A (en) | 2020-05-19 |
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CN201780095646.4A Pending CN111182942A (en) | 2017-10-03 | 2017-10-03 | Broadband electromagnetic resonator for therapeutic treatment of a pathological focus in a tissue of a living being, medical device for therapeutic treatment and method of therapeutic treatment |
Country Status (6)
Country | Link |
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US (1) | US20200246628A1 (en) |
EP (1) | EP3693058A1 (en) |
JP (1) | JP2020535901A (en) |
CN (1) | CN111182942A (en) |
RU (1) | RU2757254C1 (en) |
WO (1) | WO2019070144A1 (en) |
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WO2023102509A1 (en) * | 2021-12-03 | 2023-06-08 | Zoll Medical Corporation | Electrotherapeutic waveform and pulse generator |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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US3644807A (en) * | 1970-04-28 | 1972-02-22 | Robertshaw Controls Co | Frequency regulated inverter circuit for a synchronous motor |
EP0966988A1 (en) * | 1998-06-24 | 1999-12-29 | Santi Tofani | Apparatus and method for interfering with pathological cells survival |
RU2129449C1 (en) * | 1998-07-29 | 1999-04-27 | Закрытое акционерное общество Корпорация "Синтез" | Method for stimulating pathologic focus zone in case of inflammation process |
RU2164424C1 (en) * | 1999-06-28 | 2001-03-27 | Коноплев Сергей Петрович | Method and device for applying low frequency electromagnetic therapy |
US7610101B2 (en) * | 2006-11-30 | 2009-10-27 | Cardiac Pacemakers, Inc. | RF rejecting lead |
US9240752B2 (en) * | 2013-03-26 | 2016-01-19 | Stmicroelectronics S.R.L. | Power oscillator apparatus with transformer-based power combining |
US9667193B2 (en) * | 2014-07-30 | 2017-05-30 | Texas Instruments Incorporated | Low power wide tuning range oscillator |
-
2017
- 2017-10-03 RU RU2020111559A patent/RU2757254C1/en active
- 2017-10-03 CN CN201780095646.4A patent/CN111182942A/en active Pending
- 2017-10-03 WO PCT/RU2017/000737 patent/WO2019070144A1/en unknown
- 2017-10-03 EP EP17868499.9A patent/EP3693058A1/en not_active Withdrawn
- 2017-10-03 JP JP2020519098A patent/JP2020535901A/en active Pending
- 2017-10-03 US US16/652,213 patent/US20200246628A1/en not_active Abandoned
Also Published As
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WO2019070144A1 (en) | 2019-04-11 |
RU2757254C1 (en) | 2021-10-12 |
EP3693058A1 (en) | 2020-08-12 |
JP2020535901A (en) | 2020-12-10 |
US20200246628A1 (en) | 2020-08-06 |
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