CN111007660A - Phase contrast microscope multi-mode ultrathin light source device and using method thereof - Google Patents
Phase contrast microscope multi-mode ultrathin light source device and using method thereof Download PDFInfo
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- CN111007660A CN111007660A CN201911356154.3A CN201911356154A CN111007660A CN 111007660 A CN111007660 A CN 111007660A CN 201911356154 A CN201911356154 A CN 201911356154A CN 111007660 A CN111007660 A CN 111007660A
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- 238000000034 method Methods 0.000 title claims abstract description 10
- 238000003384 imaging method Methods 0.000 claims abstract description 28
- 239000011521 glass Substances 0.000 claims abstract description 12
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- 230000003287 optical effect Effects 0.000 claims description 6
- 238000003491 array Methods 0.000 claims description 4
- 239000003973 paint Substances 0.000 claims description 2
- 238000005286 illumination Methods 0.000 abstract description 8
- 238000000265 homogenisation Methods 0.000 abstract 1
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- 239000000463 material Substances 0.000 description 2
- 230000010363 phase shift Effects 0.000 description 2
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- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
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- 238000002135 phase contrast microscopy Methods 0.000 description 1
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
- G02B21/08—Condensers
- G02B21/14—Condensers affording illumination for phase-contrast observation
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
- G02B21/08—Condensers
- G02B21/12—Condensers affording bright-field illumination
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Citations (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT211064B (en) * | 1958-05-22 | 1960-09-10 | Janos Dipl Ing Barabas | Condenser system for simultaneous brightfield and darkfield illumination as well as for quick change of these illuminations |
JP2002369044A (en) * | 2001-06-04 | 2002-12-20 | Juki Corp | Lighting device |
CN1527047A (en) * | 2003-09-19 | 2004-09-08 | 中国科学院上海光学精密机械研究所 | Atomic beam phase contrast imaging device |
CN1725000A (en) * | 2004-07-21 | 2006-01-25 | 中国科学院上海应用物理研究所 | The method and system of X ray phase contrast imaging |
CN101918877A (en) * | 2008-01-17 | 2010-12-15 | 微阳有限公司 | Light multiplexer and recycler, and micro-projector incorporating the same |
JP2011141444A (en) * | 2010-01-07 | 2011-07-21 | Nikon Corp | Microscope system |
DE102011002030A1 (en) * | 2011-04-13 | 2012-10-18 | Jörg Piper | Method for generating high-contrast light/dark field image of object in incident-light microscope, involves generating summation image, and examining overlapping image, developed as variable bright-dark field image, in known way by eyepiece |
DE102011054106A1 (en) * | 2011-09-30 | 2013-04-04 | Jörg Piper | Method for producing variable phase contrast and/or dark-field imaging, using microscope, involves enabling light rings to make the lights pass through object, so that the summation image is arranged in the plane of intermediate image |
CN203799106U (en) * | 2014-04-30 | 2014-08-27 | 安徽三安光电有限公司 | Microscope device |
WO2014178294A1 (en) * | 2013-04-30 | 2014-11-06 | オリンパス株式会社 | Sample observation device and sample observation method |
CN105158887A (en) * | 2015-09-29 | 2015-12-16 | 南京理工大学 | Multi-mode microimaging method based on programmable LED array illumination |
JP2016145874A (en) * | 2015-02-06 | 2016-08-12 | キヤノン株式会社 | Observation apparatus, calculation method and calculation unit |
US20160363753A1 (en) * | 2015-06-12 | 2016-12-15 | Techshot, Inc. | Integrated Illuminator and Condenser for Microscopes |
CN107272178A (en) * | 2017-08-04 | 2017-10-20 | 南京理工大学 | Differential phase contrast micro imaging method based on semicircular LED illumination |
CN207336917U (en) * | 2016-03-21 | 2018-05-08 | 卡尔蔡司显微镜有限责任公司 | Microscope |
JP2018081134A (en) * | 2016-11-14 | 2018-05-24 | オリンパス株式会社 | Microscope device, dark field illumination device |
CN208207349U (en) * | 2018-03-28 | 2018-12-07 | 王艺臻 | A kind of bottom microscope LED lighting device that bioconversion medium uses |
US20190218500A1 (en) * | 2016-09-30 | 2019-07-18 | Olympus Corporation | Culture observation system |
WO2019202005A1 (en) * | 2018-04-17 | 2019-10-24 | Chemometec A/S | Depicting of objects |
CN111399207A (en) * | 2020-03-30 | 2020-07-10 | 上海观纳智能科技有限公司 | Light source and imaging light path linkage structure for inverted phase contrast microscope |
CN211123467U (en) * | 2019-12-25 | 2020-07-28 | 上海观纳智能科技有限公司 | Phase contrast microscope multi-mode ultra-thin light source device |
-
2019
- 2019-12-25 CN CN201911356154.3A patent/CN111007660B/en active Active
Patent Citations (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT211064B (en) * | 1958-05-22 | 1960-09-10 | Janos Dipl Ing Barabas | Condenser system for simultaneous brightfield and darkfield illumination as well as for quick change of these illuminations |
JP2002369044A (en) * | 2001-06-04 | 2002-12-20 | Juki Corp | Lighting device |
CN1527047A (en) * | 2003-09-19 | 2004-09-08 | 中国科学院上海光学精密机械研究所 | Atomic beam phase contrast imaging device |
CN1725000A (en) * | 2004-07-21 | 2006-01-25 | 中国科学院上海应用物理研究所 | The method and system of X ray phase contrast imaging |
CN101918877A (en) * | 2008-01-17 | 2010-12-15 | 微阳有限公司 | Light multiplexer and recycler, and micro-projector incorporating the same |
JP2011141444A (en) * | 2010-01-07 | 2011-07-21 | Nikon Corp | Microscope system |
DE102011002030A1 (en) * | 2011-04-13 | 2012-10-18 | Jörg Piper | Method for generating high-contrast light/dark field image of object in incident-light microscope, involves generating summation image, and examining overlapping image, developed as variable bright-dark field image, in known way by eyepiece |
DE102011054106A1 (en) * | 2011-09-30 | 2013-04-04 | Jörg Piper | Method for producing variable phase contrast and/or dark-field imaging, using microscope, involves enabling light rings to make the lights pass through object, so that the summation image is arranged in the plane of intermediate image |
WO2014178294A1 (en) * | 2013-04-30 | 2014-11-06 | オリンパス株式会社 | Sample observation device and sample observation method |
CN203799106U (en) * | 2014-04-30 | 2014-08-27 | 安徽三安光电有限公司 | Microscope device |
JP2016145874A (en) * | 2015-02-06 | 2016-08-12 | キヤノン株式会社 | Observation apparatus, calculation method and calculation unit |
US20160363753A1 (en) * | 2015-06-12 | 2016-12-15 | Techshot, Inc. | Integrated Illuminator and Condenser for Microscopes |
CN105158887A (en) * | 2015-09-29 | 2015-12-16 | 南京理工大学 | Multi-mode microimaging method based on programmable LED array illumination |
CN207336917U (en) * | 2016-03-21 | 2018-05-08 | 卡尔蔡司显微镜有限责任公司 | Microscope |
US20190218500A1 (en) * | 2016-09-30 | 2019-07-18 | Olympus Corporation | Culture observation system |
JP2018081134A (en) * | 2016-11-14 | 2018-05-24 | オリンパス株式会社 | Microscope device, dark field illumination device |
CN107272178A (en) * | 2017-08-04 | 2017-10-20 | 南京理工大学 | Differential phase contrast micro imaging method based on semicircular LED illumination |
CN208207349U (en) * | 2018-03-28 | 2018-12-07 | 王艺臻 | A kind of bottom microscope LED lighting device that bioconversion medium uses |
WO2019202005A1 (en) * | 2018-04-17 | 2019-10-24 | Chemometec A/S | Depicting of objects |
CN211123467U (en) * | 2019-12-25 | 2020-07-28 | 上海观纳智能科技有限公司 | Phase contrast microscope multi-mode ultra-thin light source device |
CN111399207A (en) * | 2020-03-30 | 2020-07-10 | 上海观纳智能科技有限公司 | Light source and imaging light path linkage structure for inverted phase contrast microscope |
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CN111007660B (en) | 2024-06-25 |
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Effective date of registration: 20230605 Address after: 201800 J, building 6, 1288 Yecheng Road, Jiading District, Shanghai Applicant after: Shanghai guanna Intelligent Technology Co.,Ltd. Address before: 201800 Qinghe Road 390, Shanghai, Jiading District Applicant before: Fan Yongtao |
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