CN110918149A - Centrifugal tube - Google Patents
Centrifugal tube Download PDFInfo
- Publication number
- CN110918149A CN110918149A CN201811099564.XA CN201811099564A CN110918149A CN 110918149 A CN110918149 A CN 110918149A CN 201811099564 A CN201811099564 A CN 201811099564A CN 110918149 A CN110918149 A CN 110918149A
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- China
- Prior art keywords
- brush
- centrifuge tube
- holding
- main body
- cells
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A centrifugal tube capable of accommodating a brush for collecting cells from a site to be detected of a living body, the brush including a brush head to which the cells are attached and a brush holder to which an operator holds the brush, the centrifugal tube comprising: a cylindrical centrifuge tube main body having one end closed and the other end having an opening, the centrifuge tube main body being capable of placing the brush and a collection liquid for collecting the cells from the brush into the centrifuge tube main body from the opening; a cover for closing the opening; and a holding unit for holding the brush inserted into the centrifuge tube main body.
Description
Technical Field
The invention relates to a centrifugal tube.
Background
Conventionally, when detecting the presence or absence of a tumor in a site to be detected of a living body, for example, in the cervix, trachea, or the like, cells are first collected from the site to be detected. Cells are collected from a site to be detected using a brush at the time of collecting cells, and then the cells are applied onto a Slide glass (Slide glass) by rubbing the brush (hereinafter, referred to as "rubbing method"), or the brush is put into a cell collection liquid in a dedicated container and agitated (hereinafter, referred to as "liquid detection method"), thereby collecting the cells from the brush.
In the case of the rubbing method, a large number of cells remain on the brush, and thus the cell collection efficiency is low.
Further, in the case of the liquid measuring method, the liquid is collected only by passing it through the brush in the lateral direction, and a large amount of cells remain on the brush, so that there is also a problem that the cell collection efficiency is low. Further, in the case of the liquid detection method, since the brush is merely put in the container, when the centrifugal separation is performed, the brush moves to the bottom of the container, and the cell pellet formed by the centrifugal separation is broken. Therefore, the efficiency of cell collection cannot be improved by centrifugal separation.
Further, in the case of applying the rubbing method and the liquid detection method, the operator is required to hold the brush all the time, and therefore the operator is easily infected.
Disclosure of Invention
The present invention has been made in view of the above circumstances, and a main object thereof is to provide a centrifuge tube capable of efficiently collecting cells adhering to a brush by using a centrifugal force and preventing an operator from being infected by reducing the chance of the operator coming into contact with infectious waste such as the brush.
The present invention according to claim 1 provides a centrifugal tube capable of accommodating a brush for collecting cells from a site to be detected of a living body, the brush including a brush head to which the cells are attached and a brush holder to be held by an operator, the centrifugal tube comprising: a cylindrical centrifuge tube main body having one end closed and the other end having an opening, the centrifuge tube main body being capable of placing the brush and a collection liquid for collecting the cells from the brush into the centrifuge tube main body from the opening; a cover for closing the opening; and a holding unit for holding the brush inserted into the centrifuge tube main body.
According to the present invention, since the brush is held in the centrifugal tube by the holding portion, centrifugal separation can be performed, and the cells adhered to the brush are thrown out by centrifugal force, so that the efficiency of collecting the cells can be remarkably improved. Further, according to the present invention, the operator only needs to contact the brush when fixing the brush to the centrifuge tube, and does not need to contact the brush again in the process of collecting cells later, thereby preventing the operator from being infected.
In addition, in claim 2, the holding portion is provided on the inner wall of the centrifugal tube main body, and has a groove for holding the brush head.
In claim 3, the pair of holding portions is provided so as to face each other.
Thus, since the pair of holding portions are provided so as to face each other, the brush can be held more reliably.
In claim 4, the holding part is provided on a surface of the lid facing the inside of the centrifuge tube main body, and has a recess into which the brush holder is fitted to hold the brush.
In claim 5, the holding portion is provided at a substantially center of the cover.
Further, according to claim 6, the holding portion includes: a first holding portion provided on an inner wall of the centrifugal tube main body and having a groove for holding the brush by sandwiching the brush head; and a second holding portion provided on a surface of the lid facing the interior of the centrifuge tube main body, the second holding portion having a recess into which the brush holder is fitted and holding the brush.
Thus, since the holding portions are provided at both the inner wall of the centrifuge tube main body and the lid, the brush can be held more reliably.
In claim 7, the first holding portions are provided in a pair so as to face each other.
Since the pair of first holding portions are provided so as to face each other, the brush can be held more reliably.
Drawings
Fig. 1 is a front view showing a state in which a brush is held in a centrifugal tube according to a first embodiment.
Fig. 2 is a plan view showing a state where the brush is held as viewed from the opening of the centrifugal tube according to the first embodiment.
Fig. 3 is a front view showing a state in which a brush is held in the centrifugal tube according to the second embodiment.
Fig. 4 is a cross-sectional view showing a state in which a brush is held in the centrifugal tube according to the second embodiment.
Detailed Description
The centrifugal tube of the present invention will be described below with reference to the accompanying drawings.
[ first embodiment ]
A centrifugal tube 100 according to a first embodiment will be described with reference to fig. 1 and 2. Fig. 1 is a front view showing a centrifugal tube 100 according to a first embodiment. Fig. 2 is a plan view showing a state where brush 50 is held as viewed from the opening of centrifugal tube 100 according to the first embodiment.
As shown in fig. 1, a centrifugal tube 100 of the present embodiment includes a cylindrical centrifugal tube main body 10, a lid 20, and a holding portion 30. The centrifuge tube body 10 has one end closed and the other end having an opening 11 (see fig. 2), and the brush 50 for collecting cells from a site to be examined of a living body and a collection liquid 60 for collecting cells from the brush 50 can be put into the centrifuge tube body 10. The brush 50 includes a brush head 51 to which cells are attached and a rod-shaped brush holder 52 to be held by an operator. The collection liquid 60 is placed in an amount that completely submerges the brush head 51.
The lid 20 can close the opening 11 of the centrifuge tube body 10. The holding portions 30 are provided on the inner wall of the centrifugal tube main body 10, have grooves 31 (see fig. 2) for holding the brush 50 by sandwiching the brush head 51 of the brush 50 therebetween, and a pair of the holding portions 30 are provided so as to face each other.
In the present embodiment, as shown in fig. 2, the shape of the groove 31 of the holding portion 30 corresponds to the shape of the brush head 51 of the brush 50. Specifically, the groove width of the groove 31 is slightly less than or equal to the thickness of the brush head 51. Thus, when the brush head 51 is pinched by the groove 31 of the holding portion 30, the holding portion 30 can firmly pinch the brush head 51 and hold the brush 50. It is also possible that the distance between the groove bottoms of the grooves 31 of the pair of holding portions 30 is slightly smaller than the width of the brush head 51 or equal to the width of the brush head 51. Thereby, the pair of holding portions 30 can firmly hold the brush 50 by sandwiching the brush head 51. However, the manner in which the holding portion 30 holds the brush 50 is not limited to this, and the brush may be held firmly.
Next, the operation and effect of the present embodiment will be described.
The centrifuge tube 100 of the present embodiment includes a holder 30 for holding the brush 50 from which cells have been collected on the inner wall of the centrifuge tube main body 100. Thus, according to the centrifugal tube 100 of the present embodiment, the brush 50 can be firmly held inside the centrifugal tube 100 by the holding portion 30. Therefore, even if the centrifugal separation method is used to collect the cells on the brush 50, the brush 50 does not move to the bottom of the centrifugal tube 100, and the cell pellet formed by the centrifugal separation is not scattered by the brush 50. Therefore, the cells adhered to the brush 50 can be thrown out by centrifugal force using a centrifugal separation method, and the efficiency of collecting the cells can be remarkably improved.
Further, unlike the case where the operator is required to hold the brush with his/her hand all the time when the conventional wiping method and liquid detection method are used, according to the present embodiment, the operator is only in contact with the brush 50 when the brush 50 is fixed in the centrifuge tube 100, and the brush 50 is held by the holding portion 30 and the opening 11 of the centrifuge tube 100 is closed by the lid 20 in the subsequent process of collecting cells, so that the operator does not need to be in contact with the brush 50 any more, and therefore, the operator can be effectively prevented from being infected.
Therefore, according to the centrifugal tube 100 of the present embodiment, it is possible to efficiently collect cells adhering to the brush by using the centrifugal force, and it is possible to prevent the operator from being infected by reducing the chance of the operator coming into contact with infectious waste such as the brush.
Although the case where the pair of holding portions 30 is provided has been described above, only one holding portion 30 may be provided as long as the holding portion 50 can be firmly held.
[ second embodiment ]
Next, a centrifugal tube 200 according to a second embodiment will be described with reference to fig. 3 and 4. The centrifugal tube 100 of the present embodiment is mainly different from the first embodiment in the holding portion for holding the brush 50, and the other configuration is the same as that of the first embodiment. Therefore, the holding portion will be mainly described. The same portions as those of the first embodiment are denoted by the same reference numerals.
Fig. 3 is a front view showing a state in which brush 50 is held in centrifugal tube 200 according to the second embodiment. Fig. 4 is a cross-sectional view showing a state in which the brush 50 is held in the centrifugal tube 200 according to the second embodiment.
As shown in fig. 3 and 4, the centrifugal tube 200 of the present embodiment includes a holding portion 40 instead of the holding portion 30 of the centrifugal tube 100 of the first embodiment.
The holding portion 40 is provided on a surface of the lid 20 facing the inside of the centrifuge tube main body 10, and has a recess 41 into which the brush handle 52 of the brush 50 is fitted to hold the brush 50. The holding portion 40 is provided at, for example, the approximate center of the cover 20, but is not limited to the approximate center of the cover 20.
In the present embodiment, as shown in fig. 4, the shape of the recess 41 of the holding portion 40 corresponds to the shape of the brush shaft 52 of the brush 50. Specifically, for example, the recess 41 may be a cylindrical recess having an inner diameter slightly smaller than the diameter of the brush holder 52 or equal to the diameter of the brush holder 52. Thus, when the distal end of the brush head 52 is fitted into the recess 41 of the holding portion 40, the holding portion 40 can firmly hold the brush 50. However, the manner in which the holding portion 34 holds the brush 50 is not limited to this, and the brush may be held firmly. For example, the recess 41 may also be slot-shaped with a width slightly smaller than the diameter of the handle 52 or equal to the diameter of the handle 52. Thus, when the distal end of the brush head 52 is fitted into the recess 41 of the holding portion 40, the holding portion 40 can firmly hold the brush 50. Therefore, when the lid 20 closes the opening 11 of the centrifuge tube body 10, the holding portion 40 can firmly hold the brush 50 inside the centrifuge tube 100.
Next, the operation and effect of the present embodiment will be described.
The centrifuge tube 200 of the present embodiment includes a holding portion 40 for holding the brush 50 in which the cells are collected on the surface of the lid 20 facing the inside of the centrifuge tube main body 10. Thus, according to the centrifugal tube 200 of the present embodiment, the brush 50 can be firmly held inside the centrifugal tube 100 by the holding portion 40. Therefore, even if the centrifugal separation method is used to collect the cells on the brush 50, the brush 50 does not move to the bottom of the centrifugal tube 200, and the cell pellet formed by the centrifugal separation is not scattered by the brush 50. Therefore, the cells adhered to the brush 50 can be thrown out by centrifugal force using a centrifugal separation method, and the efficiency of collecting the cells can be remarkably improved.
Further, unlike the case where the operator is required to hold the brush with his/her hand all the time when the conventional wiping method and liquid detection method are used, according to the present embodiment, the operator is only in contact with the brush 50 when the brush 50 is fixed in the centrifuge tube 200, and the brush 50 is held by the holding portion 40 in the subsequent process of collecting cells, and the opening 11 of the centrifuge tube 200 is closed by the lid 20, so that the operator is not required to be in contact with the brush 50 any more, and therefore, the operator can be effectively prevented from being infected.
Therefore, as in the first embodiment, the centrifugal tube 200 according to the present embodiment can efficiently collect the cells adhering to the brush by using the centrifugal force, and can prevent the operator from being infected by the infectious waste such as the brush by reducing the chance of the operator coming into contact with the infectious waste.
[ other embodiments ]
The first embodiment and the second embodiment have been described above, but the present invention is not limited to these embodiments. For example, although not shown, the holding portion 30 in the first embodiment and the holding portion 40 in the second embodiment may be provided in combination of the first embodiment and the second embodiment. Specifically, the centrifugal tube includes a holding portion 30 (corresponding to the "first holding portion" in the claims) for holding the brush 50 on the inner wall of the centrifugal tube main body 100, and a holding portion 40 (corresponding to the "second holding portion" in the claims) for holding the brush 50 on the surface of the lid 20 facing the inside of the centrifugal tube main body 10.
Thus, the brush 50 can be held at two places, i.e., the inner wall of the centrifuge tube main body 10 and the lid 20, by the holding part 30 and the holding part 40, and thus the brush 50 can be held more reliably. Further, as in the first and second embodiments, cells adhering to the brush can be efficiently collected by using the centrifugal force, and the chance of the operator coming into contact with infectious waste such as the brush can be reduced, thereby preventing the operator from being infected.
The embodiments of the present invention have been described above with reference to the accompanying drawings. The embodiments described above are merely specific examples of the present invention, and are not intended to limit the scope of the present invention. Those skilled in the art can modify and combine the embodiments based on the technical idea of the present invention, and the embodiments obtained thereby are also included in the scope of the present invention.
Claims (7)
1. A centrifugal tube capable of accommodating a brush for collecting cells from a site to be detected of a living body, the brush including a brush head to which the cells are attached and a brush holder to which an operator holds the brush, the centrifugal tube comprising:
a cylindrical centrifuge tube main body having one end closed and the other end having an opening, the centrifuge tube main body being capable of placing the brush and a collection liquid for collecting the cells from the brush into the centrifuge tube main body from the opening;
a cover for closing the opening; and
and a holding part for holding the brush put into the centrifuge tube main body.
2. The centrifuge tube of claim 1,
the holding part is arranged on the inner wall of the centrifuge tube main body and is provided with a groove for holding the brush by clamping the brush head.
3. The centrifuge tube of claim 2,
the holding portions are provided in a pair so as to face each other.
4. The centrifuge tube of claim 1,
the holding part is provided on a surface of the lid facing the interior of the centrifuge tube main body, and has a recess into which the brush holder is fitted to hold the brush.
5. The centrifuge tube of claim 4,
the holding portion is provided at substantially the center of the cover.
6. The centrifuge tube of claim 1,
the holding portion includes:
a first holding portion provided on an inner wall of the centrifugal tube main body and having a groove for holding the brush by sandwiching the brush head; and
and a second holding part provided on a surface of the lid facing the interior of the centrifuge tube main body, the second holding part having a recess into which the brush holder is fitted and holding the brush.
7. The centrifuge tube of claim 6,
the first holding portions are provided in a pair so as to face each other.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811099564.XA CN110918149A (en) | 2018-09-20 | 2018-09-20 | Centrifugal tube |
| PCT/CN2019/105593 WO2020057429A1 (en) | 2018-09-20 | 2019-09-12 | Centrifuge tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811099564.XA CN110918149A (en) | 2018-09-20 | 2018-09-20 | Centrifugal tube |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110918149A true CN110918149A (en) | 2020-03-27 |
Family
ID=69856150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811099564.XA Pending CN110918149A (en) | 2018-09-20 | 2018-09-20 | Centrifugal tube |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN110918149A (en) |
| WO (1) | WO2020057429A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7337907B2 (en) * | 2003-08-01 | 2008-03-04 | Polyzen, Inc. | Press-flat centrifuge tube and specimen collection assembly comprising same |
| CN101831383B (en) * | 2010-05-21 | 2012-05-02 | 中南大学 | Method and device for separating sperms |
| CN204448050U (en) * | 2015-01-30 | 2015-07-08 | 潍坊医学院 | A kind of easy mark, can the centrifuge tube of cannulate |
| CN209173958U (en) * | 2018-09-20 | 2019-07-30 | 牛尾电机(苏州)有限公司 | Centrifuge tube |
-
2018
- 2018-09-20 CN CN201811099564.XA patent/CN110918149A/en active Pending
-
2019
- 2019-09-12 WO PCT/CN2019/105593 patent/WO2020057429A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020057429A1 (en) | 2020-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200327 |