CN110916037A - Astragalus root compound beverage and preparation method thereof - Google Patents

Astragalus root compound beverage and preparation method thereof Download PDF

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Publication number
CN110916037A
CN110916037A CN201911328417.XA CN201911328417A CN110916037A CN 110916037 A CN110916037 A CN 110916037A CN 201911328417 A CN201911328417 A CN 201911328417A CN 110916037 A CN110916037 A CN 110916037A
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China
Prior art keywords
aloe
astragalus
treatment
temperature
fructus cannabis
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CN201911328417.XA
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Chinese (zh)
Inventor
曹亮
黄莉
刘欣
李振宇
高伟东
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Heilongjiang Sunshine Industry Cannabis Research Institute
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Heilongjiang Sunshine Industry Cannabis Research Institute
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Priority to CN201911328417.XA priority Critical patent/CN110916037A/en
Publication of CN110916037A publication Critical patent/CN110916037A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

An astragalus composite beverage and a preparation method thereof, belonging to the technical field of health-care beverages. Aiming at the problems of long treatment period, limited curative effect, low cure rate and repeated attack of whelk, the invention provides a traditional Chinese medicine composition beverage, which comprises the following steps: 1) mixing radix astragali, flos Lonicerae and herba Menthae with a weight ratio of 1:3: 2.6-2.8, drying, and micronizing to 800-1000 meshes; then carrying out supercritical extraction, and collecting extract liquor; 2) drying fructus cannabis; 3) grinding aloe with two stone mills, pulverizing with colloid mill, and sieving with 300-400 mesh sieve to obtain aloe solution; 4) mixing the extractive solution, aloe solution, fructus Cannabis and water at a ratio of 2-3: 5: 16-18: mixing at a mass ratio of 60-70, and putting into a jet cavitation machine for treatment to obtain a treatment liquid; 5) the astragalus composite beverage is obtained by carrying out ultrahigh-temperature instantaneous sterilization on the treatment liquid, and the astragalus composite beverage can be used for skin health care.

Description

Astragalus root compound beverage and preparation method thereof
Technical Field
The invention belongs to the technical field of health-care beverages, and particularly relates to an astragalus membranaceus compound beverage and a preparation method thereof.
Background
Acne is commonly known as a skin disease caused by the blockage and inflammation of hair follicles and sebaceous glands. At puberty, the hormones in the body stimulate the growth of hair and promote the secretion of more oil from sebaceous glands, and the hair and sebaceous glands accumulate a lot of substances, which is often seen in young men and women and is called "whelk", "pimple" or "acne". The acne not only affects beauty, but also brings psychological influence to patients and brings pain to the spirits of the patients, so in order to eliminate the acne, various medicines on the market have long treatment period, limited curative effect, low cure rate and repeated attack.
Disclosure of Invention
Aiming at the problems of long treatment period, limited curative effect, low cure rate and repeated attack of skin acne, the invention provides a traditional Chinese medicine composition beverage, which has the following technical scheme:
a radix astragali compound beverage is prepared from radix astragali, flos Lonicerae, herba Menthae, fructus Cannabis, Aloe and water.
Further defined, the astragalus mongholicus compound beverage is prepared by the following method:
1) the weight ratio of astragalus root, honeysuckle flower and mint grass is 1:3: 2.6-2.8, drying, and micronizing to 800-1000 meshes; then carrying out supercritical extraction, and collecting extract liquor;
2) drying fructus cannabis;
3) grinding aloe with two stone mills, pulverizing with colloid mill, and sieving with 300-400 mesh sieve to obtain aloe solution;
4) then, mixing the extract, the aloe liquid, the fructus cannabis and water in a ratio of 2-3: 5: 16-18: mixing at a mass ratio of 60-70, and putting into a jet cavitation machine for treatment to obtain a treatment liquid; the treatment conditions were: the pressure is 0.2MPa to 0.3MPa, the temperature is 40 ℃ to 50 ℃, and the treatment time is 18min to 30 min;
5) and (4) carrying out ultrahigh-temperature instantaneous sterilization on the treated liquid to obtain the astragalus membranaceus compound beverage.
The invention also provides a preparation method of the astragalus composite beverage, which comprises the following steps:
1) the weight ratio of astragalus root, honeysuckle flower and mint grass is 1:3: 2.6-2.8, drying, and micronizing to 800-1000 meshes; then supercritical extraction is carried out, and extract liquid is received;
2) drying fructus cannabis;
3) grinding aloe with two stone mills, pulverizing with colloid mill, and sieving with 300-400 mesh sieve to obtain aloe solution;
4) then, mixing the extract, the aloe liquid, the fructus cannabis and water in a ratio of 2-3: 5: 16-18: mixing at a mass ratio of 60-70, and putting into a jet cavitation machine for treatment to obtain a treatment liquid; the treatment conditions were: the pressure is 0.2MPa to 0.3MPa, the temperature is 40 ℃ to 50 ℃, and the treatment time is 18min to 30 min;
5) and (4) carrying out ultrahigh-temperature instantaneous sterilization on the treated liquid to obtain the astragalus membranaceus compound beverage.
Further limiting, the drying in the step 1) is carried out at the temperature of 40-50 ℃ for 4-6 h.
Further limiting, the supercritical extraction conditions in the step 1) are that the extraction pressure is 28MPa-32MPa, the extraction temperature is 40-50 ℃, the frequency is 50Hz-60Hz, and the extraction time is 2-3 h.
Further limiting, the fructus cannabis in the step 2) is dried for 6h-8h at the temperature of 38-42 ℃.
Further defined, the treatment conditions in step 4) are: the pressure is 0.28MPa to 0.3MPa, the temperature is 45 ℃ to 50 ℃, and the treatment time is 18min to 20 min.
Further defining the conditions of the ultra-high temperature instant sterilization in the step 5) as the sterilization temperature of 138-140 ℃; the sterilization time is 8-12 s.
Advantageous effects
The invention selects the traditional Chinese medicine formula, and combines the astragalus root, the honeysuckle, the mint, the fructus cannabis and the aloe in a compatibility manner to prepare the beverage product with the function of conditioning the skin, has short treatment period, good curative effect and high cure rate, is not easy to relapse compared with a medicine coated on the beverage product, and can be used for skin health care.
Detailed Description
Example 1. preparation of astragalus membranaceus composite beverage.
1) Mixing the astragalus, the honeysuckle and the mint at a mass ratio of 1:3:2.6, and drying at a low temperature of 40 ℃ for 6 hours; then carrying out superfine grinding to 800 meshes, carrying out supercritical extraction under the conditions of extraction pressure of 28MPa, extraction temperature of 40 ℃, frequency of 50Hz and extraction time of 2h, and collecting the extract for later use.
2) Drying fructus Cannabis at low temperature of 38 deg.C for 8 hr.
3) Sequentially grinding aloe with one stone mill and two stone mills, pulverizing with colloid mill, and sieving with 300 mesh sieve to obtain aloe solution.
4) Mixing the extract prepared in the step 1), the aloe liquid obtained in the step 3), the fructus cannabis dried in the step 2) and water in a ratio of 2: 5: 16: 60, then putting the mixture into a jet cavitation machine for treatment under the pressure of 0.2MPa and the temperature of 40 ℃ for 30min to obtain a treatment solution.
5) Then, the treated liquid is sterilized instantly at 138 ℃ for 8s at ultrahigh temperature, and is canned in an aseptic manner to obtain the finished beverage.
Example 2 preparation of astragalus membranaceus composite beverage.
1) Mixing the astragalus, the honeysuckle and the mint at a mass ratio of 1:3:2.8, and drying at a low temperature of 50 ℃ for 4 hours; then micronizing to 1000 mesh, performing supercritical extraction under conditions of extraction pressure 32MPa, extraction temperature 50 deg.C, frequency 60Hz, and extraction time 3h, and collecting extractive solution.
2) Drying fructus Cannabis at low temperature of 42 deg.C for 6 h.
3) Sequentially grinding aloe with one stone mill and two stone mills, pulverizing with colloid mill, and sieving with 400 mesh sieve to obtain aloe solution.
4) Mixing the extract prepared in the step 1), the aloe liquid obtained in the step 3), the fructus cannabis dried in the step 2) and water in a proportion of 3: 5: 18: 70, then putting the mixture into a jet cavitation machine for treatment under the pressure of 0.3MPa and the temperature of 50 ℃ for 20min to obtain a treatment solution.
5) Then, the treated liquid is sterilized instantly at 140 ℃ and 12s ultra high temperature, and is canned in an aseptic manner to obtain the finished beverage.
Example 3 preparation of astragalus membranaceus composite beverage.
1) Mixing the astragalus, the honeysuckle and the mint at a mass ratio of 1:3:2.8, and drying at a low temperature of 50 ℃ for 5 hours; then micronizing to 1000 mesh, performing supercritical extraction under the conditions of extraction pressure of 30MPa, extraction temperature of 50 deg.C, frequency of 60Hz, and extraction time of 3h, and collecting the extractive solution.
2) Drying fructus Cannabis at low temperature of 40 deg.C for 6 h.
3) Sequentially grinding aloe with one stone mill and two stone mills, pulverizing with colloid mill, and sieving with 400 mesh sieve to obtain aloe solution.
4) Mixing the extract prepared in the step 1), the aloe liquid obtained in the step 3), the fructus cannabis dried in the step 2) and water in a proportion of 3: 5: 18: 70, then putting the mixture into a jet cavitation machine for treatment under the pressure of 0.3MPa and the temperature of 45 ℃ for 20min to obtain a treatment solution.
5) Then, the treated liquid is sterilized instantly at 140 ℃ and 12s ultra high temperature, and is canned in an aseptic manner to obtain the finished beverage.

Claims (8)

1. The astragalus composite beverage is characterized by being prepared from astragalus, honeysuckle, mint grass, fructus cannabis, aloe and water.
2. The astragalus membranaceus compound beverage as claimed in claim 1, which is prepared by the following method:
1) the weight ratio of astragalus root, honeysuckle flower and mint grass is 1:3: 2.6-2.8, drying, and micronizing to 800-1000 meshes; then carrying out supercritical extraction, and collecting extract liquor;
2) drying fructus cannabis;
3) grinding aloe with two stone mills, pulverizing with colloid mill, and sieving with 300-400 mesh sieve to obtain aloe solution;
4) then, mixing the extract, the aloe liquid, the fructus cannabis and water in a ratio of 2-3: 5: 16-18: mixing at a mass ratio of 60-70, and putting into a jet cavitation machine for treatment to obtain a treatment liquid; the treatment conditions were: the pressure is 0.2MPa to 0.3MPa, the temperature is 40 ℃ to 50 ℃, and the treatment time is 18min to 30 min;
5) and (4) carrying out ultrahigh-temperature instantaneous sterilization on the treated liquid to obtain the astragalus membranaceus compound beverage.
3. The preparation method of the astragalus mongholicus compound beverage according to claim 1 or 2, which is characterized by comprising the following steps:
1) the weight ratio of astragalus root, honeysuckle flower and mint grass is 1:3: 2.6-2.8, drying, and micronizing to 800-1000 meshes; then carrying out supercritical extraction, and collecting extract liquor;
2) drying fructus cannabis;
3) grinding aloe with two stone mills, pulverizing with colloid mill, and sieving with 300-400 mesh sieve to obtain aloe solution;
4) then, mixing the extract, the aloe liquid, the fructus cannabis and water in a ratio of 2-3: 5: 16-18: mixing at a mass ratio of 60-70, and putting into a jet cavitation machine for treatment to obtain a treatment liquid; the treatment conditions were: the pressure is 0.2MPa to 0.3MPa, the temperature is 40 ℃ to 50 ℃, and the treatment time is 18min to 30 min;
5) and (4) carrying out ultrahigh-temperature instantaneous sterilization on the treated liquid to obtain the astragalus membranaceus compound beverage.
4. The preparation method according to claim 3, wherein the drying in step 1) is carried out at a temperature of 40 ℃ to 50 ℃ for 4 to 6 hours.
5. The preparation method according to claim 3, wherein the supercritical extraction conditions in step 1) are extraction pressure of 28MPa-32MPa, extraction temperature of 40-50 ℃, frequency of 50Hz-60Hz, and extraction time of 2-3 h.
6. The preparation method of claim 3, wherein the fructus cannabis in step 2) is dried for 6-8 h at 38-42 ℃.
7. The method according to claim 3, wherein the treatment conditions in step 4) are: the pressure is 0.28MPa to 0.3MPa, the temperature is 45 ℃ to 50 ℃, and the treatment time is 18min to 20 min.
8. The preparation method according to claim 3, wherein the condition of the ultra-high temperature instantaneous sterilization in the step 5) is a sterilization temperature of 138-140 ℃; the sterilization time is 8-12 s.
CN201911328417.XA 2019-12-20 2019-12-20 Astragalus root compound beverage and preparation method thereof Pending CN110916037A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102246993A (en) * 2010-12-23 2011-11-23 东莞市德亨饮料食品有限公司 Hemp seed and aloe beverage and preparation method thereof
WO2013013496A1 (en) * 2011-07-25 2013-01-31 江西食方食坊中药食品有限公司 Drink composition for clearing inner heat and preparation method thereof
CN103371942A (en) * 2012-04-16 2013-10-30 张斌 Traditional Chinese medicine acne-removing mask
CN105851748A (en) * 2016-04-01 2016-08-17 李国清 Radix astragali compound fatigue preventing drink and preparation method thereof
CN106668629A (en) * 2015-11-11 2017-05-17 王国成 Traditional Chinese recipe for treating whelk

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102246993A (en) * 2010-12-23 2011-11-23 东莞市德亨饮料食品有限公司 Hemp seed and aloe beverage and preparation method thereof
WO2013013496A1 (en) * 2011-07-25 2013-01-31 江西食方食坊中药食品有限公司 Drink composition for clearing inner heat and preparation method thereof
CN103371942A (en) * 2012-04-16 2013-10-30 张斌 Traditional Chinese medicine acne-removing mask
CN106668629A (en) * 2015-11-11 2017-05-17 王国成 Traditional Chinese recipe for treating whelk
CN105851748A (en) * 2016-04-01 2016-08-17 李国清 Radix astragali compound fatigue preventing drink and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
国家药典委员会著: "《中华人民共和国药典临床用药须知 中药饮片卷 2015年版》", 31 October 2017, 中国医药科技出版社 *
郁东海等主编: "《治未病学》", 30 June 2018, 上海科学技术出版社 *

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Application publication date: 20200327