CN110812464A - 一种防治关节炎的药物组合物及其制备方法 - Google Patents
一种防治关节炎的药物组合物及其制备方法 Download PDFInfo
- Publication number
- CN110812464A CN110812464A CN201911370147.9A CN201911370147A CN110812464A CN 110812464 A CN110812464 A CN 110812464A CN 201911370147 A CN201911370147 A CN 201911370147A CN 110812464 A CN110812464 A CN 110812464A
- Authority
- CN
- China
- Prior art keywords
- parts
- pharmaceutical composition
- prepared
- preventing
- treating arthritis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/237—Notopterygium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种防治关节炎的药物组合物,由以下重量份的原料制备而成:铁牛七10~20份、桑寄生10~20份、当归尾5~15份、宽筋滕10~20份、没药10~20份、当归尾10~20份、羌活5~15份、姜黄3~5份、制附片3~5份、栀子3~5份、肉桂5~10份、独活5~15份、蓖麻子5~10份、细辛5~10份、生马钱子3~5份、小蓟10~20份、松节10~20份。本方具有温经散寒,散结消肿,祛瘀止痛的功效,有利于关节软骨细胞的修复与再生。药效实验表明本发明药物组合物可明显降低关节液中IL‑1、TNF‑α的含量,减轻滑膜炎症,另外还具有明显的镇痛作用,表明其对关节炎有较好的治疗作用。
Description
技术领域
本发明涉及中药制剂领域,具体涉及一种防治关节炎的药物组合物及其制备方法。
背景技术
关节炎的病因尚不完全明确,临床表现以关节的红、肿、热、痛、功能 障碍及关节畸形为主要症状。目前,治疗关节炎常用的化学药物主要为非甾 体抗炎药,包括布洛芬、阿司匹林、双氯芬酸等,然而,这类药物普遍对胃肠道粘膜有明显的刺激作用,且副作用较大,限制了其在临床上的使用。
发明内容
为解决上述问题,本发明提供了一种防治关节炎的药物组合物及其制备方法,所得药物组合物疗效较好的同时不具有明显的副作用和不良反应。
为实现上述目的,本发明采取的技术方案为:
一种防治关节炎的药物组合物,由以下重量份的原料制备而成:
铁牛七10~20份、桑寄生10~20份、当归尾5~15份、宽筋滕10~20份、没药10~20份、当归尾10~20份、羌活5~15份、姜黄3~5份、制附片3~5份、栀子3~5份、肉桂5~10份、独活5~15份、蓖麻子5~10份、细辛5~10份、生马钱子3~5份、小蓟10~20份、松节10~20份。
优选地,由以下重量份的原料制备而成:
铁牛七10份、桑寄生10份、当归尾5份、宽筋滕10份、没药10份、当归尾10份、羌活5份、姜黄3份、制附片3份、栀子3份、肉桂5份、独活5份、蓖麻子5份、细辛5份、生马钱子3份、小蓟10份、松节10份。
优选地,由以下重量份的原料制备而成:
铁牛七20份、桑寄生20份、当归尾15份、宽筋滕20份、没药20份、当归尾20份、羌活15份、姜黄5份、制附片5份、栀子5份、肉桂10份、独活15份、蓖麻子10份、细辛10份、生马钱子5份、小蓟20份、松节20份。
优选地,由以下重量份的原料制备而成:
铁牛七15份、桑寄生15份、当归尾10份、宽筋滕15份、没药15份、当归尾15份、羌活10份、姜黄4份、制附片4份、栀子4份、肉桂7.5份、独活10份、蓖麻子7.5份、细辛7.5份、生马钱子4份、小蓟15份、松节15份。
进一步地,该药物组合物为由各重量配比原料药的纳米级药粉、水或有机溶剂、植物油的提取物,加上药学上可接受的辅料或者辅助性成分制备而成的制剂。
进一步地,所述制剂为酊剂、软膏剂、黑膏药、白膏药、橡胶膏剂、贴膏剂、糊剂或涂膜剂。
本发明还提供了上述药物组合物的制备方法,包括如下步骤:取各重量配比的原料药,直接破碎成纳米级的中药粉,或再加入水、有机溶剂或植物油提取,再加入药学上可接受的辅料或者辅助性成分,即得。
本发明具有以下有益效果:
本方具有温经散寒,散结消肿,祛瘀止痛的功效,局部用药可以直接作用于关节及周围组织,改善骨及软骨的血液循环,促进了炎症病灶的消退及增生病变的软化和吸收,改善了机体免疫功能,从而有利于关节软骨细胞的修复与再生。药效实验表明本发明药物组合物可明显降低关节液中IL-1、TNF-α的含量,减轻滑膜炎症,另外还具有明显的镇痛作用,表明其对关节炎有较好的治疗作用。
具体实施方式
为了使本发明的目的及优点更加清楚明白,以下结合实施例对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。
实施例1
一种防治关节炎的药物组合物,通过以下步骤制备所得:
S1、按重量份称取:铁牛七20份、桑寄生20份、当归尾15份、宽筋滕20份、没药20份、当归尾20份、羌活15份、姜黄5份、制附片5份、栀子5份、肉桂10份、独活15份、蓖麻子10份、细辛10份、生马钱子5份、小蓟20份、松节20份;
S2、将称取的铁牛七、桑寄生、当归尾、宽筋滕、没药、当归尾、羌活、姜黄、制附片、栀子、肉桂、独活、蓖麻子、细辛、生马钱子、小蓟、松节破碎至纳米级,烘干,杀菌,得中药粉;
S3、将所得的中药粉用蜂蜜调匀,摊于棉垫上,绷带包扎,2日换药1次。
实施例2
一种防治关节炎的药物组合物,通过以下步骤制备所得:
S1、按重量份称取:铁牛七10份、桑寄生10份、当归尾5份、宽筋滕10份、没药10份、当归尾10份、羌活5份、姜黄3份、制附片3份、栀子3份、肉桂5份、独活5份、蓖麻子5份、细辛5份、生马钱子3份、小蓟10份、松节10份;
S2、将称取的铁牛七、桑寄生、当归尾、宽筋滕、没药、当归尾、羌活、姜黄、制附片、栀子、肉桂、独活、蓖麻子、细辛、生马钱子、小蓟、松节破碎至纳米级,得中药粉;
S3、将所得的中药粉用6倍量的80%的乙醇溶液浸泡40min,400w微波提取两次,每次400S,合并两次所得的提取液,50~60℃减压回收乙醇,浓缩至相对密度为1.10~1.20的清膏,即得,将药膏涂抹在患处,早晚各一次。
实施例3
一种防治关节炎的药物组合物,通过以下步骤制备所得:
S1、按重量份称取:铁牛七15份、桑寄生15份、当归尾10份、宽筋滕15份、没药15份、当归尾15份、羌活10份、姜黄4份、制附片4份、栀子4份、肉桂7.5份、独活10份、蓖麻子7.5份、细辛7.5份、生马钱子4份、小蓟15份、松节15份;
S2、将称取的铁牛七、桑寄生、当归尾、宽筋滕、没药、当归尾、羌活、姜黄、制附片、栀子、肉桂、独活、蓖麻子、细辛、生马钱子、小蓟、松节破碎至纳米级,得中药粉;
S3、将所得的中药粉用6倍量的80%的乙醇溶液浸泡40min,400w微波提取两次,每次400S,合并两次所得的提取液,浓缩至目标含量的酊剂,即得,每次用量5ml,早晚各一次。
药效实验表明本发明药物组合物可明显降低关节液中IL-1、TNF-α的含量,减轻滑膜炎症,另外还具有明显的镇痛作用,表明其对关节炎有较好的治疗作用。
以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以作出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。
Claims (7)
1.一种防治关节炎的药物组合物,其特征在于,由以下重量份的原料制备而成:
铁牛七10~20份、桑寄生10~20份、当归尾5~15份、宽筋滕10~20份、没药10~20份、当归尾10~20份、羌活5~15份、姜黄3~5份、制附片3~5份、栀子3~5份、肉桂5~10份、独活5~15份、蓖麻子5~10份、细辛5~10份、生马钱子3~5份、小蓟10~20份、松节10~20份。
2.如权利要求1所述的一种防治关节炎的药物组合物,其特征在于,由以下重量份的原料制备而成:
铁牛七10份、桑寄生10份、当归尾5份、宽筋滕10份、没药10份、当归尾10份、羌活5份、姜黄3份、制附片3份、栀子3份、肉桂5份、独活5份、蓖麻子5份、细辛5份、生马钱子3份、小蓟10份、松节10份。
3.如权利要求1所述的一种防治关节炎的药物组合物,其特征在于,由以下重量份的原料制备而成:
铁牛七20份、桑寄生20份、当归尾15份、宽筋滕20份、没药20份、当归尾20份、羌活15份、姜黄5份、制附片5份、栀子5份、肉桂10份、独活15份、蓖麻子10份、细辛10份、生马钱子5份、小蓟20份、松节20份。
4.如权利要求1所述的一种防治关节炎的药物组合物,其特征在于,由以下重量份的原料制备而成:
铁牛七15份、桑寄生15份、当归尾10份、宽筋滕15份、没药15份、当归尾15份、羌活10份、姜黄4份、制附片4份、栀子4份、肉桂7.5份、独活10份、蓖麻子7.5份、细辛7.5份、生马钱子4份、小蓟15份、松节15份。
5.如权利要求1所述的一种防治关节炎的药物组合物,其特征在于,该药物组合物为由各重量配比原料药的纳米级药粉、水或有机溶剂、植物油的提取物,加上药学上可接受的辅料或者辅助性成分制备而成的制剂。
6.如权利要求5所述的一种防治关节炎的药物组合物,其特征在于,所述制剂为酊剂、软膏剂、黑膏药、白膏药、橡胶膏剂、贴膏剂、糊剂或涂膜剂。
7.一种权利要求1~7任意一项所述药物组合物的制备方法,其特征在于:包括如下步骤:取各重量配比的原料药,直接破碎成纳米级的中药粉,或再加入水、有机溶剂或植物油提取,再加入药学上可接受的辅料或者辅助性成分,即得。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911370147.9A CN110812464A (zh) | 2019-12-26 | 2019-12-26 | 一种防治关节炎的药物组合物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911370147.9A CN110812464A (zh) | 2019-12-26 | 2019-12-26 | 一种防治关节炎的药物组合物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN110812464A true CN110812464A (zh) | 2020-02-21 |
Family
ID=69546448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201911370147.9A Pending CN110812464A (zh) | 2019-12-26 | 2019-12-26 | 一种防治关节炎的药物组合物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN110812464A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113230365A (zh) * | 2021-06-04 | 2021-08-10 | 陕西秦岭七药协同创新中心有限公司 | 一种治疗关节骨病的中药组合物、制剂及其制备方法和应用 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1368047A (zh) * | 2001-01-29 | 2002-09-11 | 李性钠 | 风湿膏药的制备方法 |
CN1623570A (zh) * | 2003-12-04 | 2005-06-08 | 李天祥 | 一种治疗关节病、骨质增生的外用中药 |
CN102552823A (zh) * | 2012-02-23 | 2012-07-11 | 山西黄河中药有限公司 | 一种治疗骨性关节炎的药物及其制备方法 |
CN105770041A (zh) * | 2016-03-07 | 2016-07-20 | 成都市飞龙水处理技术研究所青白江第分所 | 一种治疗风湿痹阻所导致的关节肿痛的中药组合物 |
CN107184947A (zh) * | 2017-07-25 | 2017-09-22 | 成都中医药大学附属医院 | 一种治疗骨关节类疾病的药物组合物及其制备方法和用途 |
CN107551229A (zh) * | 2017-07-25 | 2018-01-09 | 成都中医药大学附属医院 | 一种药物组合物及其制备方法和用途 |
CN109331109A (zh) * | 2018-11-30 | 2019-02-15 | 张明 | 一种治疗颈肩腰腿痛的中药组合物及其制备方法 |
-
2019
- 2019-12-26 CN CN201911370147.9A patent/CN110812464A/zh active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1368047A (zh) * | 2001-01-29 | 2002-09-11 | 李性钠 | 风湿膏药的制备方法 |
CN1623570A (zh) * | 2003-12-04 | 2005-06-08 | 李天祥 | 一种治疗关节病、骨质增生的外用中药 |
CN102552823A (zh) * | 2012-02-23 | 2012-07-11 | 山西黄河中药有限公司 | 一种治疗骨性关节炎的药物及其制备方法 |
CN105770041A (zh) * | 2016-03-07 | 2016-07-20 | 成都市飞龙水处理技术研究所青白江第分所 | 一种治疗风湿痹阻所导致的关节肿痛的中药组合物 |
CN107184947A (zh) * | 2017-07-25 | 2017-09-22 | 成都中医药大学附属医院 | 一种治疗骨关节类疾病的药物组合物及其制备方法和用途 |
CN107551229A (zh) * | 2017-07-25 | 2018-01-09 | 成都中医药大学附属医院 | 一种药物组合物及其制备方法和用途 |
CN109331109A (zh) * | 2018-11-30 | 2019-02-15 | 张明 | 一种治疗颈肩腰腿痛的中药组合物及其制备方法 |
Non-Patent Citations (2)
Title |
---|
刘世峰: "《传承中医》", 31 January 2010, 中国古籍出版社 * |
林鸣: "综合疗法治疗踝关节骨折42例", 《中国民间疗法》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113230365A (zh) * | 2021-06-04 | 2021-08-10 | 陕西秦岭七药协同创新中心有限公司 | 一种治疗关节骨病的中药组合物、制剂及其制备方法和应用 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102614389A (zh) | 一种中药贴剂 | |
CN101524450B (zh) | 一种正骨舒筋的口服中药及其制备方法 | |
CN110812464A (zh) | 一种防治关节炎的药物组合物及其制备方法 | |
CN101366935A (zh) | 治疗软组织损伤外用超微粉中药制剂及其制备方法 | |
CN103127438A (zh) | 一种治疗风湿骨痛的中药制剂及制备方法 | |
CN1035717C (zh) | 内服促使骨折愈合接骨散的制备方法 | |
CN102526275B (zh) | 一种用于治疗痛风的药物及其制备方法 | |
CN1115165C (zh) | 一种跌打风湿外用药酒及其制备方法 | |
CN1216615C (zh) | 一种治疗风湿病症和腰肌劳损外用膏药及制备方法 | |
CN111228445A (zh) | 消肿化瘀跌打药酒及其制备方法 | |
CN1256134C (zh) | 治疗类风湿的药物组合物 | |
CN116370529B (zh) | 一种用于治疗风湿病的外用中药组合物及其制备方法和应用 | |
CN1233333C (zh) | 藏药制剂的制备方法 | |
CN1903244A (zh) | 一种治疗性功能障碍的中药组合物 | |
CN103316203B (zh) | 一种用于治疗扭伤的外用中药 | |
CN1090502C (zh) | 一种治疗骨质增生、软组织损伤的外用中药 | |
CN1355036A (zh) | 抗骨痛膏制品及制备方法 | |
CN105687730A (zh) | 一种用于局部止痛的复方延胡索中药组合物 | |
CN100496600C (zh) | 一种治疗骨质增生的药物及其制备方法 | |
CN1084748A (zh) | 速效关节炎敷剂及其制造方法 | |
CN116966261A (zh) | 一种治疗风湿用膏药 | |
CN105169054A (zh) | 一种治疗急慢性骨关节炎的中药制剂及其制备方法 | |
CN113274466A (zh) | 一种用于类风湿关节炎的药物及其制备方法 | |
CN104491132A (zh) | 一种治疗筋伤骨病的中药正骨巴布膏贴 | |
CN104740066A (zh) | 活血祛瘀复原膏 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200221 |