CN110801319A - Magnesium alloy vertebral artery degradable stent - Google Patents
Magnesium alloy vertebral artery degradable stent Download PDFInfo
- Publication number
- CN110801319A CN110801319A CN201911117128.5A CN201911117128A CN110801319A CN 110801319 A CN110801319 A CN 110801319A CN 201911117128 A CN201911117128 A CN 201911117128A CN 110801319 A CN110801319 A CN 110801319A
- Authority
- CN
- China
- Prior art keywords
- vertebral artery
- magnesium alloy
- support
- stent
- connecting rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00035—Other metals or alloys
- A61F2310/00041—Magnesium or Mg-based alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/0097—Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
Abstract
The invention discloses a magnesium alloy vertebral artery degradable stent, relates to the technical field of vertebral artery stents, and particularly comprises a stent outer frame, wherein two ends of the stent outer frame are movably connected with one end of a diamond-shaped stent through connecting pins, and the diamond-shaped stent are movably connected with one end of a connecting rod through the connecting pins. This magnesium alloy vertebral artery degradable support, through the selection of vertebral artery degradable support magnesium alloy material, the speed effect of magnesium alloy's support in human degradation is better, the mesh that the support degradation time reduces has been reached, through horizontal and fore-and-aft setting to the connecting rod pipe, can realize support diameter grow under the effect of gasbag, play the supporting role to vertebral artery, setting through a dead lever on the rhombus, can make the length of support lengthen through the toper push rod, play the better protection effect to pathological change blood vessel, it can change the size at the diametric (al) to have reached the support, can also change the purpose of size at length direction.
Description
Technical Field
The invention relates to the technical field of vertebral artery stents, in particular to a magnesium alloy vertebral artery degradable stent.
Background
Atherosclerosis of the vertebral arterial system is one of the major causes of post-circulatory stroke, with about one-fifth of post-circulatory stroke occurring in the extracranial segment of the vertebral artery. Symptomatic vertebral artery stenosis has a number of treatment options: the second-level prevention is carried out by using anti-platelet aggregation drugs alone, and the annual stroke incidence rate is still up to 15%; warfarin treatment has the same effect as aspirin treatment, but the risk of bleeding is greatly increased; the surgical operation is complex, the risk is high, and the wide development in clinic is limited. Vertebral artery stenosis has little curative effect in drug treatment, high surgical risk and too large limitation, and endovascular treatment has gradually become a trend. Atherosclerotic stenosis can occur throughout the vertebral artery, but is most common with the initiation of the emergence of the vertebral artery from the subclavian artery. In addition, the initial part of the vertebral artery has more variation, the advantage of the vertebral artery on one side often appears, and the vertebral artery on the other side is thinner from the initial section to the intracranial section, and even the difference between the tube diameters of the left and right vertebral arteries is about 1-2 times or more. This also results in a thinner side vessel that is more susceptible to restenosis after stenting. From histological feature analysis, the blood vessel wall at the starting part of the vertebral artery contains a large amount of smooth muscle rich in elastin, and has larger rebound force for the stent. The vertebral artery itself emerges at almost right angles from the subclavian artery, with the distal end relatively mobile and the proximal end fixed by the bony thorax and following the respiratory activity of the thorax, which inevitably causes fatigue of the stent. Therefore, vertebral artery stents require a high level of radial support while also requiring a high level of fatigue resistance and lesion throughput.
However, in the prior art, the vertebral artery stent has a lot of defects, in the aspect of materials, the vertebral artery stent is degraded in a human body at a low speed, the treatment effect is overlong, and the vertebral artery stent can only be longitudinally expanded under the action of the air bag and cannot change the length of the vertebral artery stent.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a magnesium alloy vertebral artery degradable stent, which solves the problems in the background technology.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme: the magnesium alloy vertebral artery degradable stent comprises a stent outer frame, wherein two ends of the stent outer frame are movably connected with one end of a rhombic stent through connecting pins, and the rhombic stent is movably connected with the rhombic stent through one end of the connecting pin and the connecting rod.
Optionally, a fixing rod is welded on one side of one of the rhombic supports in the support outer frame, and one end of the fixing rod is provided with a tapered hole.
Optionally, the connecting holes are formed in the two ends of the connecting rod, and the connecting rod is of a hollow structure.
Optionally, the diamond-shaped stent is made of magnesium alloy, and the magnesium alloy is made of degradable materials such as calcium and zinc.
Optionally, the support frame is radially connected with ten rhombic supports, and the support frame is axially and movably connected with ten rhombic supports.
Optionally, the material density of the side of the connecting rod close to the vertebral artery is high, and the material density of the side of the connecting rod far away from the vertebral artery is low.
Optionally, the middle of the connecting rod is cylindrical, and the two ends of the connecting rod are rectangular.
Optionally, the four rods of the diamond-shaped support are all rectangular, and the thicknesses of the two ends of the diamond-shaped support are thinner than that of the middle of the diamond-shaped support.
Optionally, the diameter of the cylindrical portion of the tie bar is 0.01mm, and the thickness of the rectangular portion of the tie bar is 0.008 mm.
(III) advantageous effects
The invention provides a magnesium alloy vertebral artery degradable stent which has the following beneficial effects:
1. according to the magnesium alloy vertebral artery degradable stent, through selection of magnesium alloy materials of the vertebral artery degradable stent, after medicines needed by the vertebral artery of a human body are completely absorbed, the magnesium alloy stent has a better speed effect on degradation of the human body, and the purpose of reducing the degradation time of the stent is achieved
2. This magnesium alloy vertebral artery degradable support through to the horizontal and fore-and-aft setting of connecting rod, can realize the support diameter grow under the effect of gasbag, plays the supporting role to vertebral artery, through the setting of a dead lever on the rhombus, can make the length of support lengthen through the toper push rod, plays the better protection effect to pathological change blood vessel, has reached and has made the support can change the size at the diametric (al) direction, can also change the purpose of size at support length direction.
Drawings
FIG. 1 is a schematic front view of the structure of the present invention;
FIG. 2 is a schematic three-dimensional structure of a connecting rod according to the present invention;
fig. 3 is a partially enlarged structural schematic view of the fixing rod of the present invention.
In the figure: 1-support outer frame, 2-connecting pin, 3-diamond support, 4-connecting rod, 5-fixing rod, 6-conical hole and 7-connecting hole.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Referring to fig. 1 to 3, the present invention provides a technical solution: the magnesium alloy vertebral artery degradable stent comprises a stent outer frame 1, wherein the rhombic stent is made of magnesium alloy, the magnesium alloy is made of degradable materials such as calcium and zinc, ten rhombic stents 3 are radially connected to the stent outer frame 1, the ten rhombic stents 3 are axially and movably connected to the stent outer frame 1, two ends of the stent outer frame 1 are movably connected with one ends of the rhombic stents 3 through connecting pins 2, a fixing rod is welded to one side of one of the rhombic stents in the stent outer frame, one end of the fixing rod 5 is provided with a tapered hole 6, four rods of the rhombic stent 3 are rectangular, the thicknesses of two ends of the rhombic stent 3 are thinner than those of the middle of the rhombic stent, the rhombic stent 3 is movably connected with one end of a connecting rod 4 through the connecting pin 2, two ends of the connecting rod 4 are provided with connecting holes 7, the connecting rod 4 is of a hollow structure, and the material density of one side of the connecting rod, the material density of one side that vertebral artery was kept away from to connecting rod 4 is little, and the shape at 4 middle parts of connecting rod is the cylinder, and the shape at 4 both ends of connecting rod is the rectangle, and the diameter of the cylinder part of connecting rod 4 is 0.01mm, and the rectangle part thickness of connecting rod 4 is 0.008 mm.
During the use, when human vertebral artery goes wrong and needs install the support additional, the inside of magnesium alloy vertebral artery degradable support is put into to the gasbag under the circumstances that does not aerify, when putting magnesium alloy vertebral artery degradable support to the position of pathological change vertebral artery, when the support length does not have pathological change vertebral artery long term, use the dead lever of push rod promotion support several faces to make it support pathological change vertebral artery completely, then the gasbag is aerifyd, at this moment can make rhombus support and connecting rod stretched, vertebral artery to the pathological change plays supporting role, the medicine of magnesium alloy vertebral artery degradable support outside parcel can be slowly absorbed by pathological change vertebral artery under the support of support, wait after the medicine is absorbed completely, magnesium alloy vertebral artery support degradation slowly, absorb by the human body at last and disappear.
In summary, the following steps: this magnesium alloy vertebral artery degradable support, through the selection of vertebral artery degradable support magnesium alloy material, after the medicine that human vertebral artery needs is absorbed completely, magnesium alloy's support is better at the speed effect of human degradation, the purpose that has reached the reduction of support degradation time is through horizontal and fore-and-aft setting to the connecting rod, can realize support diameter grow under the effect of gasbag, play the supporting role to vertebral artery, setting through a dead lever on the rhombus, can make the length of support grow through the toper push rod, play the better protection effect to pathological change blood vessel, reached the support can also can change the purpose of size at support length direction at diameter direction change size.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (9)
1. Magnesium alloy vertebral artery degradable stent, including support frame (1), its characterized in that: the support frame is characterized in that two ends of the support frame (1) are movably connected with one end of the rhombic support (3) through the connecting pin (2), and the rhombic support (3) is movably connected with one end of the rhombic support through the connecting pin (2) and the connecting rod (4).
2. The magnesium alloy vertebral artery degradable stent of claim 1, wherein: a fixing rod (5) is welded on one side of one rhombic support (3) in the support outer frame (1), and a tapered hole (6) is formed in one end of the fixing rod (5).
3. The magnesium alloy vertebral artery degradable stent of claim 1, wherein: connecting holes (7) are formed in the two ends of the connecting rod (4), and the connecting rod (4) is of a hollow structure.
4. The magnesium alloy vertebral artery degradable stent of claim 1, wherein: the rhombic support (3) is made of magnesium alloy, and the magnesium alloy is made of degradable materials such as calcium, zinc and the like.
5. The magnesium alloy vertebral artery degradable stent of claim 1, wherein: the radial direction of support frame (1) is connected with ten rhombus supports (3), the axial swing joint of support frame (1) has ten rhombus supports (3).
6. The magnesium alloy vertebral artery degradable stent of claim 1, wherein: the material density of one side of the connecting rod (4) close to the vertebral artery is high, and the material density of one side of the connecting rod (4) far away from the vertebral artery is low.
7. The magnesium alloy vertebral artery degradable stent of claim 1, wherein the shape of the middle part of the connecting rod (4) is cylindrical, and the shape of the two ends of the connecting rod (4) is rectangular.
8. The magnesium alloy vertebral artery degradable stent of claim 1, wherein the four rods of the diamond-shaped stent (3) are all rectangular in shape, and the thickness of the two ends of the diamond-shaped stent (3) is thinner than that of the middle of the diamond-shaped stent.
9. The magnesium alloy vertebral artery degradable stent of claim 1, wherein the diameter of the cylindrical part of the connecting rod (4) is 0.01mm, and the thickness of the rectangular part of the connecting rod (4) is 0.008 mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911117128.5A CN110801319A (en) | 2019-11-15 | 2019-11-15 | Magnesium alloy vertebral artery degradable stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911117128.5A CN110801319A (en) | 2019-11-15 | 2019-11-15 | Magnesium alloy vertebral artery degradable stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110801319A true CN110801319A (en) | 2020-02-18 |
Family
ID=69490080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911117128.5A Pending CN110801319A (en) | 2019-11-15 | 2019-11-15 | Magnesium alloy vertebral artery degradable stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110801319A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113599036A (en) * | 2021-08-18 | 2021-11-05 | 江苏大学 | Flexible blood vessel support applied to peripheral blood vessels |
| CN113599036B (en) * | 2021-08-18 | 2024-05-14 | 江苏大学 | Flexible vascular stent applied to peripheral blood vessel |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199872A (en) * | 2006-12-14 | 2008-06-18 | 天津市凯迪亚医疗器械有限公司 | Double medicament controlled-release coating micropore ACS bracket |
| CN101594839A (en) * | 2006-10-18 | 2009-12-02 | 革新控股有限责任公司 | Support with flexible hinge |
| CN103948460A (en) * | 2008-10-10 | 2014-07-30 | 雷瓦医药公司 | Expandable slide and lock stent |
| CN206934215U (en) * | 2016-12-30 | 2018-01-30 | 先健科技(深圳)有限公司 | Artificial heart valve film device and its leaflet and rack body |
| CN108261251A (en) * | 2016-12-30 | 2018-07-10 | 先健科技(深圳)有限公司 | Intraluminal stent and its transport system |
| US20180280165A1 (en) * | 2015-02-11 | 2018-10-04 | Abbott Cardiovascular Systems Inc. | Scaffolds having radiopaque markers |
| CN108785755A (en) * | 2018-06-28 | 2018-11-13 | 王缨 | Application of the magnesium alloy in preparing degradable biliary tract rack |
-
2019
- 2019-11-15 CN CN201911117128.5A patent/CN110801319A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101594839A (en) * | 2006-10-18 | 2009-12-02 | 革新控股有限责任公司 | Support with flexible hinge |
| CN101199872A (en) * | 2006-12-14 | 2008-06-18 | 天津市凯迪亚医疗器械有限公司 | Double medicament controlled-release coating micropore ACS bracket |
| CN103948460A (en) * | 2008-10-10 | 2014-07-30 | 雷瓦医药公司 | Expandable slide and lock stent |
| US20180280165A1 (en) * | 2015-02-11 | 2018-10-04 | Abbott Cardiovascular Systems Inc. | Scaffolds having radiopaque markers |
| CN206934215U (en) * | 2016-12-30 | 2018-01-30 | 先健科技(深圳)有限公司 | Artificial heart valve film device and its leaflet and rack body |
| CN108261251A (en) * | 2016-12-30 | 2018-07-10 | 先健科技(深圳)有限公司 | Intraluminal stent and its transport system |
| CN108785755A (en) * | 2018-06-28 | 2018-11-13 | 王缨 | Application of the magnesium alloy in preparing degradable biliary tract rack |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113599036A (en) * | 2021-08-18 | 2021-11-05 | 江苏大学 | Flexible blood vessel support applied to peripheral blood vessels |
| CN113599036B (en) * | 2021-08-18 | 2024-05-14 | 江苏大学 | Flexible vascular stent applied to peripheral blood vessel |
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| PB01 | Publication | ||
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Application publication date: 20200218 |