CN110772595A - Medicinal and edible composition as well as preparation method and application thereof - Google Patents
Medicinal and edible composition as well as preparation method and application thereof Download PDFInfo
- Publication number
- CN110772595A CN110772595A CN201911126352.0A CN201911126352A CN110772595A CN 110772595 A CN110772595 A CN 110772595A CN 201911126352 A CN201911126352 A CN 201911126352A CN 110772595 A CN110772595 A CN 110772595A
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- medicinal
- edible composition
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- following components
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Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
The invention relates to the technical field of food and medicine, and discloses a medicinal and edible composition which comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry and 5-30% of poria cocos; the invention also discloses a preparation method of the medicinal and edible composition; the invention also discloses an application of the medicinal and edible composition in preparing medicines and foods for treating insomnia and climacteric syndrome. The traditional Chinese medicine composition is safe and mild in medicine effect, can promote sleep, improve sleep quality and prolong sleep time, has natural, safe and no side effect in medicine components, has a good treatment effect on insomnia patients, and particularly has a good effect on certain long-term intractable insomnia; meanwhile, the composition also has the efficacy of treating climacteric syndrome and has the health-care benefit for human bodies.
Description
Technical Field
The invention relates to the technical field of food and medicine, in particular to a medicinal and edible composition as well as a preparation method and application thereof.
Background
Insomnia is a disorder characterized by frequent failure to achieve normal sleep, and is mainly manifested by difficulty in falling asleep, low depth of sleep, wakefulness when sleeping, lusterless sleep, inability to sleep again after waking or insomnia all over the night. Insomnia is also known as lying in, sleeping in, or ocular or contemplative in the book of Nei Jing Yue quan Shu & insomnia, etc., the theory of Jing Yue quan Shu & insomnia: although insomnia is usually not enough, it is best to know the pathogenic factors and healthy qi at all . Insomnia is caused by yin deficiency, and the spirit is dominant, and the spirit is caused by insomnia; those who are uneasy to do so are disturbed by pathogenic qi and deficient by nutritive qi. Therefore, the insomnia is classified into deficiency and excess in the traditional Chinese medicine, wherein the deficiency refers to spleen deficiency, heart and liver blood deficiency, malnutrition of the mind and insomnia; the excessive syndrome may cause insomnia due to qi stagnation or damp (phlegm) obstruction affecting the qi movement of spleen and stomach, disturbing heart-mind. The heart, liver, gallbladder, spleen, stomach and kidney disorders and uneasiness are caused by the disturbance of fire, heat, depression, blood stasis, phlegm, dampness and dryness, or qi and blood deficiency of the zang-fu organs, such as yin-blood deficiency and disharmony between the heart and kidney.
The insomnia causes fatigue feeling, general anxiety, fine headache, reaction delay, hypnosis, anxiety, depression, anxiety, depression, anxiety, depression, anxiety, depression.
In summary, there is an urgent need to develop a drug which is natural, has no side effects, is safe and mild, and can effectively improve sleep and prevent or treat insomnia to solve the pain of patients.
Disclosure of Invention
Based on the problems, the invention provides a medicinal and edible composition, and a preparation method and application thereof.
In order to solve the technical problems, the invention provides a medicinal and edible composition, which comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry and 5-30% of poria cocos.
Furthermore, the rose flower also comprises 5 to 15 weight percent of rose flower.
Further, the feed also comprises 5 to 30 weight percent of oyster.
Further, the paint also comprises the following components in percentage by weight: 5 to 30 percent of oyster and 5 to 15 percent of rose.
Further, the paint also comprises the following components in percentage by weight: 5 to 30 percent of longan pulp and 5 to 15 percent of rose.
Further, the paint also comprises the following components in percentage by weight: 3-20% of ginseng and 5-30% of longan pulp.
Further, the paint also comprises the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster and 5-15% of rose.
Further, the paint also comprises the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia and 3-15% of fermented soybean.
Further, the paint also comprises the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia, 3-15% of fermented soybean and 5-15% of finger citron.
Further, the paint also comprises the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia, 3-15% of fermented soybean, 5-15% of fingered citron, 5-30% of wheat, 5-10% of liquorice and 5-15% of Chinese date.
In order to solve the technical problems, the invention also provides a preparation method of the medicinal and edible composition, which comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
In order to solve the technical problems, the invention also provides application of the medicinal and edible composition in preparing medicines and foods for treating insomnia and climacteric syndrome.
Compared with the prior art, the invention has the beneficial effects that: the traditional Chinese medicine composition is safe and mild in medicine effect, can promote sleep, improve sleep quality and prolong sleep time, has natural, safe and no side effect in medicine components, has a good treatment effect on insomnia patients, and particularly has a good effect on certain long-term intractable insomnia; meanwhile, the composition also has the efficacy of treating climacteric syndrome and has the health-care benefit for human bodies.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples, and the exemplary embodiments and descriptions thereof are only used for explaining the present invention and are not used as limitations of the present invention.
Example 1:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry and 5-30% of poria cocos.
Semen Ziziphi Spinosae has effects of nourishing liver, calming heart, arresting sweating and promoting fluid production, has physiological function of improving sleep, and can be used for treating vexation, insomnia, palpitation, dreaminess, asthenia, hyperhidrosis, body fluid deficiency, and thirst; the gamma-aminobutyric acid is an important inhibitory neurotransmitter in the central nervous system, can supplement the inhibitory neurotransmitter of a human body, and has the physiological effects of sedation, convulsion resistance and anxiety resistance; bulbus Lilii has effects of nourishing yin and moistening lung, clearing heart fire and tranquilization, and can be used for treating diseases such as yin deficiency and dry cough, fatigue cough and hemoptysis, vexation and pavor, insomnia and dreaminess, absentmindedness, etc., and modern research shows that it has good sedative hypnotic effect; semen Nelumbinis has effects of invigorating spleen, relieving diarrhea, invigorating kidney, astringing, and tranquilizing mind, and can be used for treating insomnia, dreaminess, insomnia, amnesia, vexation, thirst, lumbago, asthenia, deafness, nocturnal emission, stranguria, chronic dysentery, diarrhea, metrorrhagia, leukorrhagia, and anorexia due to stomach deficiency; rhizoma polygonati has the effects of tonifying qi and yin, strengthening spleen, moistening lung and tonifying kidney, can be used for treating symptoms such as deficiency of spleen-stomach qi, tiredness and hypodynamia, stomach-yin deficiency, dry mouth and poor appetite, lung deficiency and dry cough, over-strained cough and hemoptysis, insufficiency of essence and blood, soreness and weakness of waist and knees, early white beard and hair, internal heat and thirst quenching and the like, and is often combined for improving insomnia by virtue of the sweet and flat property and the functions of tonifying qi, yin and tonifying kidney, and an expected curative effect is achieved; mulberry is sweet and cold in nature, enters liver and kidney channels, has the effects of nourishing yin and supplementing blood, promoting fluid production and moistening dryness, can treat liver and kidney deficiency, heart and kidney imbalance and other diseases, and can treat sleep disorder of the old at the same time; poria has effects of promoting diuresis, eliminating dampness, invigorating spleen, and calming heart, and can be used for treating edema oliguria, phlegm and fluid retention, dizziness and palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, insomnia, etc., and has hypnotic effect in modern research.
The formula has reasonable compatibility and obvious effect through repeated clinical verification. Wherein the gamma-aminobutyric acid has the effects of tranquilizing and allaying excitement, the spina date seed, the lily, the lotus seed and the poria cocos have the effects of nourishing blood, tonifying spleen, nourishing heart and allaying excitement, the rhizoma polygonati and the mulberry have the effects of nourishing liver and kidney and replenishing qi and blood, and the lily, the lotus seed, the rhizoma polygonati and the mulberry have the effects of restoring consciousness, invigorating heart and kidney. The composition has effects of tranquilizing mind, nourishing heart and kidney, invigorating qi, nourishing blood, and nourishing liver and kidney, and can be used for treating both symptoms and root causes of insomnia patients, thereby achieving ideal sleep improving effect.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 2:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos and 5-15% of rose.
Rose is sweet and slightly bitter in nature, and mild in property. Has effects in regulating qi, regulating blood, removing toxic materials, caring skin, regulating blood circulation, inducing resuscitation, dispersing stagnated liver qi, activating spleen, promoting bile secretion, promoting digestion, and regulating mechanism. The food herbal term means that the food has the effects of benefiting lung and spleen, benefiting liver and gallbladder, and is fragrant, sweet and beautiful in taste and refreshing. ' Long-term taking has the efficacies of benefiting lung, calming heart, strengthening spleen, stimulating appetite and beautifying.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 3:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos and 5-30% of oyster.
Concha Ostreae has effects of tranquilizing mind, subsiding yang, nourishing yin, softening hard mass and resolving hard mass, and can be used for treating palpitation and insomnia, giddiness tinnitus, lymphoid tuberculosis and subcutaneous nodule, and lump in abdomen. Pharmacological research shows that the oyster has the effects of calming and local anesthesia, can inhibit nerve and muscle excitation, resist experimental gastric ulcer damage and enhance the immune function, and the formula can play a very good role in calming the nerves.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 4:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 5-30% of oyster and 5-15% of rose.
The oyster can calm and calm the nerves, and the rose can soothe the liver, relieve depression and regulate the mind, thereby playing a better role in calming the nerves.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 5:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 5-30% of arillus longan and 5-15% of rose.
Arillus longan has effects of invigorating heart and spleen, nourishing blood, and tranquilizing mind, and can be used for treating deficiency of qi and blood, cardiopalmus, severe palpitation, amnesia, insomnia, blood deficiency, and sallow complexion; the rose has the effects of soothing liver-qi stagnation, benefiting lung, calming heart, strengthening spleen and stimulating appetite. The two complement each other to better treat insomnia.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 6:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 3-20% of ginseng and 5-30% of arillus longan.
Ginseng radix has effects of invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production and tranquilizing mind, and can be used for treating asthenia, desire for depletion, cold limbs, slight pulse, spleen deficiency, anorexia, lung deficiency, cough and asthma, body fluid deficiency, thirst, internal heat, diabetes, asthenia, palpitation, insomnia, sexual impotence, cold womb, heart failure and cardiogenic shock. Arillus longan has effects of invigorating heart and spleen, nourishing blood and tranquillizing, and can be used for treating deficiency of qi and blood, cardiopalmus, severe palpitation, amnesia, insomnia, blood deficiency and chlorosis. Shen nong Ben Cao Jing: mainly tonify five internal organs, calm spirit, stop palpitation, remove pathogenic qi, improve eyesight, benefit heart and promote intelligence. The insomnia patients often have insufficient qi and blood and no spirit is attached, so the ginseng and the longan pulp can tonify qi and blood, the spirit can be stored, and the night sleep is stable. The formula can play a very good role in soothing the nerves.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 7:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 3-20% of ginseng, 5-30% of arillus longan, 5-30% of oyster and 5-15% of rose.
The ginseng and the arillus longan have the effects of tonifying qi, nourishing blood and tranquillizing, the oyster is calmed, the rose is soothed liver and stabilizes mind, and the whole formula can calm heart, harmonize heart and kidney, tonify qi, nourish blood, nourish liver and kidney, sooth liver and nourish heart, thereby achieving the purpose of treating insomnia.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 8:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 3-20% of ginseng, 5-30% of arillus longan, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia and 3-15% of fermented soybean.
Gardenia has the effects of purging fire, relieving restlessness, clearing heat, promoting diuresis, cooling blood and removing toxicity, and can be used for relieving swelling and pain by external application. Can be used for treating febrile vexation, damp-heat jaundice, stranguria with pain, hematemesis, epistaxis, conjunctival congestion, swelling and pain, and pyocutaneous disease; external treatment can be used for sprain and contusion pain, and modern research shows that the cape jasmine fruit has the effects of hypnosis, sedation, anticonvulsive and memory promotion; semen Sojae Preparatum has effects of relieving exterior syndrome, relieving restlessness, dispersing depressed vital energy and removing toxic substance, and can be used for treating typhoid fever and fever, headache, dysphoria and chest distress etc., and modern pharmacological research shows that semen Sojae Preparatum has effects of regulating blood lipid, resisting arteriosclerosis, resisting osteoporosis, resisting tumor, reducing blood sugar and regulating immunity etc. The prescription of the combination of gardenia and fermented soybean is called gardenia and fermented soybean soup, which is specially used for treating vexation and insomnia in the treatise on typhoid and miscellaneous diseases of traditional Chinese medicine. Therefore, the combination of gardenia and fermented soybean can better achieve the effect of improving sleep.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 9:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 3-20% of ginseng, 5-30% of arillus longan, 5-30% of oyster, 5-15% of rose, 3-15% of cape jasmine, 3-15% of fermented soybean and 5-15% of fingered citron.
The fingered citron has the effects of soothing liver, regulating qi, harmonizing stomach, relieving pain, eliminating dampness and reducing phlegm, and is mainly used for treating qi stagnation of liver and stomach, distending pain of chest and hypochondrium, epigastric fullness, anorexia, vomiting and cough with excessive phlegm. The fingered citron is added to enhance the effect of soothing the liver and regulating qi so as to smooth the emotion and play a better nerve-soothing effect.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to the preparation of medicaments for treating insomnia and climacteric syndrome.
Example 10:
a medicinal and edible composition comprises the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry, 5-30% of poria cocos, 3-20% of ginseng, 5-30% of arillus longan, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia, 3-15% of fermented soybean, 5-15% of fingered citron, 5-30% of wheat, 5-10% of liquorice and 5-15% of Chinese date.
Semen Tritici Aestivi has effects of nourishing heart, removing heat, quenching thirst and arresting sweating, and can be used for treating hysteria, dysphoria, diabetes, hyperhidrosis, diarrhea, carbuncle swelling, traumatic hemorrhage and scald. The liquorice, wheat and Chinese date combined prescription is called the liquorice, wheat and Chinese date soup, and the prescription is an effective prescription for treating the climacteric syndrome insomnia and the unstable emotion, so the three ingredients are added to better play a role in improving the sleep, and especially have obvious effect on the insomnia and the emotion change caused by the climacteric syndrome.
The preparation method of the medicinal and edible composition comprises the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
The medicinal and edible composition can be applied to preparation of medicines and foods for treating insomnia and climacteric syndrome.
The medicine-food homologous composition is used for treating 85 insomnia patients and partial climacteric syndrome patients, and typical cases comprise the following five patients:
(1) zheng Mr. Shen, 48 years old, professor university, intractable insomnia for more than 10 years, difficulty in falling asleep, easy to wake up, difficult to fall asleep after waking up; the effect is poor by taking western medicine hypnotic and other methods for treatment for a long time, and the patient can sleep for about 3 hours every night; zheng Mr. can fall asleep quickly in half a month after taking the medicine of the invention, can sleep for more than 6 hours every night, and symptoms such as physical fatigue and anorexia are obviously improved;
(2) the dang ladies are 35 years old, and teachers in kindergartens have intractable insomnia for more than ten years and are accompanied with symptoms of irregular menstruation and dark spots on the cheeks, and can fall asleep quickly after taking one dose of the medicine, and can fall asleep normally after taking eight doses of the medicine;
(3) the plum lady is 27 years old, is researched and born, has insomnia for more than 1 year, is aggravated by the aggravation of study and experiment tasks, is difficult to fall asleep all night, is dim and has poor sperm sinking in the daytime, and seriously influences study and work, and after the medicine is taken for one week, the sleep is obviously improved, and the sleep is normal after the medicine is taken for another week;
(4) the male women aged 65 years old, retired doctors in hospitals, sleep disorder is more than 5 years old, dreaminess is easy to wake up, and patients can fall asleep after taking treatment such as Shulediazepam and the like frequently, but early morning, dizziness and hypodynamia, symptoms are obviously improved after taking the medicine for one week, and deep sleep can reach 5 to 6 hours;
(5) liu lady, 50 years old, individual management household, dysphoria and insomnia more than 1 year, with heat perspiration, diagnosis climacteric syndrome, taking the formula for 3 days, sleep is improved obviously, dysphoria is relieved obviously, taking the formula for 7 days, sleep is normal, can sleep for 7 hours every day, heat perspiration disappears, patients are very happy, and the curative effect of the formula is very definite.
The invention can promote sleep, improve sleep quality, prolong sleep time, and is safe and free of side effect. Practice proves that the traditional Chinese medicine composition has good treatment effect on clinical insomnia patients and climacteric syndrome patients, and particularly has good effect on long-term intractable insomnia.
The above is an embodiment of the present invention. The embodiments and specific parameters in the embodiments are only for the purpose of clearly illustrating the process of verifying the invention and are not intended to limit the scope of the invention, which is defined by the claims, and all the equivalent structural changes made by applying the content of the specification of the invention should be covered by the scope of the invention.
Claims (12)
1. The medicinal and edible composition is characterized by comprising the following components in percentage by weight: 5-30% of spina date seed, 0.05-0.5% of gamma-aminobutyric acid, 5-30% of lily, 5-30% of lotus seed, 5-30% of rhizoma polygonati, 5-30% of mulberry and 5-30% of poria cocos.
2. The composition as claimed in claim 1, further comprising 5-15 wt% of rose.
3. The composition as claimed in claim 1, which further comprises 5-30 wt% of oyster.
4. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 5 to 30 percent of oyster and 5 to 15 percent of rose.
5. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 5 to 30 percent of longan pulp and 5 to 15 percent of rose.
6. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 3-20% of ginseng and 5-30% of longan pulp.
7. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster and 5-15% of rose.
8. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia and 3-15% of fermented soybean.
9. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia, 3-15% of fermented soybean and 5-15% of finger citron.
10. The medicinal and edible composition as claimed in claim 1, further comprising the following components in percentage by weight: 3-20% of ginseng, 5-30% of longan pulp, 5-30% of oyster, 5-15% of rose, 3-15% of gardenia, 3-15% of fermented soybean, 5-15% of fingered citron, 5-30% of wheat, 5-10% of liquorice and 5-15% of Chinese date.
11. The preparation method of the medicinal and edible composition as claimed in any one of claims 1-11, characterized by comprising the following steps:
s1: weighing each component of the medicinal and edible composition except gamma-aminobutyric acid, uniformly mixing, decocting for 2-3 times, pouring out the decoction for later use after each time of decoction is finished, adding water with the volume 6-12 times of the total volume of the medicinal and edible composition before each time of decoction, pouring the decoctions together after each time of decoction is finished, standing for 12h, and filtering to obtain a filtrate;
s2: evaporating and concentrating the filtrate obtained in the step S1 to be thick paste, drying and crushing the thick paste, adding gamma-aminobutyric acid and grinding the powder into powder;
s3, mixing the powder obtained in the step S2 with β -cyclodextrin, crushing into fine powder, and preparing the fine powder into granules, paste, oral liquid, capsules, tablets or pills according to actual needs.
12. Use of the composition as a medicine and food according to any one of claims 1 to 11 for the preparation of a medicament and food for the treatment of insomnia and climacteric syndrome.
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