CN110755673A - Sodium carboxymethylcellulose liquid dressing and preparation method thereof - Google Patents
Sodium carboxymethylcellulose liquid dressing and preparation method thereof Download PDFInfo
- Publication number
- CN110755673A CN110755673A CN201911079515.4A CN201911079515A CN110755673A CN 110755673 A CN110755673 A CN 110755673A CN 201911079515 A CN201911079515 A CN 201911079515A CN 110755673 A CN110755673 A CN 110755673A
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- CN
- China
- Prior art keywords
- cmc
- purified water
- carboxymethyl cellulose
- preservative
- sodium carboxymethylcellulose
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
Abstract
A sodium carboxymethylcellulose liquid dressing and a preparation method thereof belong to the technical field of medical supplies. The sodium carboxymethyl cellulose liquid dressing consists of sodium carboxymethyl cellulose (CMC-Na), purified water and a preservative. Microbial limit requirements: the total number of aerobic bacteria is not more than 100 per 1 mL; the total number of the moulds and the yeasts is not more than 10 per 1 mL; staphylococcus aureus and Pseudomonas aeruginosa were not detected. The component proportion (weight ratio) is as follows: 0.5-50.00% of sodium carboxymethylcellulose (CMC-Na) and proper amounts of purified water and preservative. The process method comprises the following steps: weighing raw materials according to the formula ratio (weight ratio), putting the raw material sodium carboxymethyl cellulose (CMC-Na) and the preservative into a container with purified water, fully dissolving the raw materials to prepare a solution, uniformly stirring and subpackaging. The protective layer is formed on the surface of the wound surface to play a role of physical barrier. Is used for nursing superficial wounds such as small wounds, bruises, cut wounds and the like and peripheral skin.
Description
Technical Field
The invention belongs to the technical field of medical supplies made of main raw materials of high polymer material sodium carboxymethyl cellulose (CMC-Na), purified water and a preservative.
Background
The problem of skin superficial surface damage such as skin wound and trauma is a common phenomenon in normal life of people, once skin causes trauma and a wound occurs, measures must be taken to prevent wound surface infection, the degree of wound pollution is greatly related to whether infection occurs later, and general wounds are classified as follows: 1. clean wound (Clean-Wounds) -no inflammation phenomenon. 2. Clean-Contaminated Wounds (Clean-Contaminated Wounds) -no significant contamination. 3. Contaminated Wounds (Contaminated Wounds) - - -have acute inflammation, but not suppuration. Traumatic wounds with necrotic tissue. 4. Infected Wounds (Dirty or Infected Wounds) - - - -Infected Wounds.
Current wound treatment methods generally include:
(1) disinfecting with iodine tincture or alcohol or purple water, and rubbing from inside to outside along the wound edge without applying iodine tincture or alcohol into the wound. If foreign matters exist in the wound, the foreign matters need to be carefully treated and taken out.
(2) The small wound may be coated with mercurous chloride (especially when it is noted that mercurous chloride, iodine tincture, iodophor and any iodine-containing disinfectant cannot be used simultaneously or excessively) or mercurous chloride.
The above wound treatment methods have some disadvantages, the wound is easily in a dry condition, the open wound should not be allowed to dry completely, and the tissue at the bottom of the wound is damaged by dehydration. Epithelial cells are more difficult to move under dry scabs than moist wound surfaces. This is detrimental to wound healing.
Disclosure of Invention
The invention aims to provide sodium carboxymethyl cellulose liquid dressing and a manufacturing method thereof, which play a role of physical barrier by forming a protective layer on the surface of a wound surface. Is used for nursing superficial wounds such as small wounds, bruises, cut wounds and the like and peripheral skin.
The technical scheme of the invention is as follows:
the invention has the structural components as follows: consists of sodium carboxymethylcellulose (CMC-Na), purified water and preservative. Is not provided aseptically. The microbial limit requirements (total amount of aerobic bacteria is not more than 100 per 1mL, total amount of mould and microzyme is not more than 10 per 1mL, staphylococcus aureus and pseudomonas aeruginosa are not detected).
The sodium carboxymethylcellulose liquid dressing comprises the following components in percentage by weight: 0.1-50.00% of sodium carboxymethylcellulose (CMC-Na), a proper amount of purified water and a proper amount of preservative.
The process method comprises the following steps: weighing raw materials according to a formula proportion, putting the raw materials of sodium carboxymethylcellulose (CMC-Na) and the preservative into a container with purified water, fully dissolving the raw materials to prepare a solution, uniformly stirring, and subpackaging.
The main raw material of the invention is sodium carboxymethylcellulose (CMC-Na), which is a high molecular water-soluble compound and is a film-forming material commonly used in medical consumables.
The technical problems to be solved by the invention are as follows: the liquid dressing is prepared by adopting sodium carboxymethylcellulose (CMC-Na), purified water and a preservative as main raw materials, has the characteristic of forming a gel protective layer on a wound surface, plays a role of physical barrier, isolates bacteria, has moisture absorption performance, ensures proper temperature and humidity healing conditions of the wound surface, and plays a role in promoting the healing of the wound surface. The characteristics ensure that the dressing covers the wound surface, prevents macromolecular substances and bacteria from invading, ensures the gas exchange between the wound surface and the outside, and creates conditions for ensuring that the wound surface is in a closed, warm and humid environment. Thereby promoting the healing of superficial wound surfaces such as small wounds, bruises, cut wounds and the like. Makes up the deficiency of the existing drying problem in the aspect of wound treatment.
The application range of the invention is as follows: the protective layer is formed on the surface of the wound surface, so that the physical barrier effect is achieved. For small wound and eraser
Nursing superficial wound surface such as wound and incised wound and peripheral skin.
The moist closed dressing consists of sodium carboxymethylcellulose (CMC-Na), purified water and a preservative, has the characteristic of forming a gel protective layer on a wound surface, plays a role of physical barrier, isolates bacteria, has moisture absorption performance, ensures proper temperature and humidity healing conditions of the wound surface, and plays a role of promoting the healing of the wound surface. The characteristics ensure that the dressing covers the wound surface, prevents macromolecular substances and bacteria from invading, ensures the gas exchange between the wound surface and the outside, and creates conditions for ensuring that the wound surface is in a closed, warm and humid environment. Thereby promoting the healing of superficial wound surfaces such as small wounds, bruises, cut wounds and the like. Makes up the deficiency of the existing drying problem in the aspect of wound treatment.
Detailed Description
1. Weighing the raw materials according to the formula proportion (weight ratio): 0.5-20.00% of sodium carboxymethylcellulose (CMC-Na), a proper amount of purified water and a proper amount of preservative.
2. Weighing raw materials according to a formula proportion according to a process method, putting the raw materials of sodium carboxymethyl cellulose (CMC-Na) and an antiseptic into a container with purified water, fully dissolving the raw materials to prepare a solution, uniformly stirring and subpackaging.
Claims (5)
1. A sodium carboxymethylcellulose liquid dressing is characterized by consisting of sodium carboxymethylcellulose (CMC-Na), purified water and a preservative.
2. The sodium carboxymethyl cellulose liquid dressing of claim 1, wherein the microbial limit requirements are: the total number of aerobic bacteria is not more than 100 per 1 mL; the total number of the moulds and the yeasts is not more than 10 per 1 mL; staphylococcus aureus and Pseudomonas aeruginosa were not detected.
3. The sodium carboxymethyl cellulose liquid dressing as claimed in claim 1, which is characterized by comprising the following components in percentage by weight: 0.1-50.00% of sodium carboxymethylcellulose (CMC-Na), a proper amount of purified water and a proper amount of preservative.
4. A liquid dressing of sodium carboxymethyl cellulose is prepared through proportioning raw materials, mixing sodium carboxymethyl cellulose (CMC-Na) and antiseptic, dissolving in purified water, stirring and packing.
5. The sodium carboxymethyl cellulose liquid dressing according to claim 1 or 3, wherein the weight ratio of the formulation is as follows: 0.5-20.00% of sodium carboxymethylcellulose (CMC-Na), a proper amount of purified water and a proper amount of preservative.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911079515.4A CN110755673A (en) | 2019-11-07 | 2019-11-07 | Sodium carboxymethylcellulose liquid dressing and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911079515.4A CN110755673A (en) | 2019-11-07 | 2019-11-07 | Sodium carboxymethylcellulose liquid dressing and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110755673A true CN110755673A (en) | 2020-02-07 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911079515.4A Pending CN110755673A (en) | 2019-11-07 | 2019-11-07 | Sodium carboxymethylcellulose liquid dressing and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN110755673A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111481736A (en) * | 2020-04-16 | 2020-08-04 | 济南秦鲁药业科技有限公司 | Spray dressing for superficial wound surface and preparation method thereof |
| CN115581798A (en) * | 2022-11-01 | 2023-01-10 | 珠海市雅莎医疗器械有限公司 | Liquid wound dressing for improving dark skin color and preparation method thereof |
Citations (5)
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|---|---|---|---|---|
| WO2008002196A1 (en) * | 2006-06-19 | 2008-01-03 | Lev Davidovich Rasnetsov | Pharmaceutical composition for treating burns (variants) and a method for the production thereof (variants) |
| CN101559236A (en) * | 2009-02-12 | 2009-10-21 | 泰州市三易医疗科技有限公司 | Silver-bearing hydrocolloid dressing and preparation method |
| CN101569758A (en) * | 2008-12-31 | 2009-11-04 | 褚加冕 | Preparation method for medical use hydrocolloid dressing |
| CN103446618A (en) * | 2013-09-16 | 2013-12-18 | 河南科高辐射化工科技有限公司 | Antibacterial hydrogel wound coating film and wound paste prepared by using coating film |
| WO2018004739A1 (en) * | 2016-06-29 | 2018-01-04 | Iview Therapeutics, Inc. | Novel rapid-deposition thin-film forming compositions as effective wound care treatment |
-
2019
- 2019-11-07 CN CN201911079515.4A patent/CN110755673A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008002196A1 (en) * | 2006-06-19 | 2008-01-03 | Lev Davidovich Rasnetsov | Pharmaceutical composition for treating burns (variants) and a method for the production thereof (variants) |
| CN101569758A (en) * | 2008-12-31 | 2009-11-04 | 褚加冕 | Preparation method for medical use hydrocolloid dressing |
| CN101559236A (en) * | 2009-02-12 | 2009-10-21 | 泰州市三易医疗科技有限公司 | Silver-bearing hydrocolloid dressing and preparation method |
| CN103446618A (en) * | 2013-09-16 | 2013-12-18 | 河南科高辐射化工科技有限公司 | Antibacterial hydrogel wound coating film and wound paste prepared by using coating film |
| WO2018004739A1 (en) * | 2016-06-29 | 2018-01-04 | Iview Therapeutics, Inc. | Novel rapid-deposition thin-film forming compositions as effective wound care treatment |
Non-Patent Citations (4)
| Title |
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| PARK, JONG-SEOK: "Chestnut Honey Impregnated Carboxymethyl Cellulose Hydrogel for Diabetic Ulcer Healing", 《POLYMERS》 * |
| 张丽红: "《现代伤口护理实用手册》", 30 June 2013 * |
| 许伟石等: "《烧伤创面修复》", 30 October 2013 * |
| 陶岚: "羧甲基纤维素钠敷料在急性伤口中的应用", 《现代临床医学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111481736A (en) * | 2020-04-16 | 2020-08-04 | 济南秦鲁药业科技有限公司 | Spray dressing for superficial wound surface and preparation method thereof |
| CN115581798A (en) * | 2022-11-01 | 2023-01-10 | 珠海市雅莎医疗器械有限公司 | Liquid wound dressing for improving dark skin color and preparation method thereof |
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Application publication date: 20200207 |
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