CN110755578A - External traditional Chinese medicine for treating plantar wart and preparation method thereof - Google Patents
External traditional Chinese medicine for treating plantar wart and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an external traditional Chinese medicine for treating verruca plantaris and a preparation method thereof, belonging to the technical field of medicines and comprising the following raw material medicines in parts by weight: 5-10 parts of folium artemisiae argyi, 5-10 parts of isatis root, 6-9 parts of radix sophorae flavescentis, 6-9 parts of curcuma zedoary, 10-15 parts of rhizoma smilacis glabrae, 10-15 parts of purslane, 6-9 parts of safflower, 6-9 parts of peach kernel, 10-15 parts of folium isatidis, 10-15 parts of spina gleditsiae and 10-15 parts of scouring rush. The invention also provides a preparation method of the external traditional Chinese medicine for treating plantar wart. The external traditional Chinese medicine for treating plantar wart is a pure traditional Chinese medicine preparation, has the advantages of simple formula, external treatment, high safety, no side effect, low cost and strong practicability.
Description
Technical Field
The invention belongs to the technical field of medicines, and relates to an external traditional Chinese medicine for treating plantar wart and a preparation method thereof.
Background
Human Papilloma Virus (HPV) is a genus of Papilloma vacuolatum Virus a belonging to the papovaviridae family. HPV is one of the most common viruses in human population, and the severity of symptoms mainly depends on the toxicity of the virus, the number of viruses and the immune state of the body. Viral regulation disturbs the regulation of cell growth and differentiation, and mature keratinocytes continue to divide and proliferate, causing skin thickening (or warts) characteristic of various papillomavirus infections.
Plantar wart is an ordinary wart occurring at the plantar part, the skin lesion is a tiny and bright papule at the beginning, the papule gradually increases later, the surface is cornified, the verruca is rough and uneven, the verruca is gray, gray yellow or light gray, the center is slightly concave, the periphery is provided with a slightly yellow and high cutin ring, loose white papillary keratin can be seen after the cutin on the surface is removed, the bleeding is easy after the skin is pricked by a needle, the verruca can be fused into a sheet when the number is large, the roughness at the center is uneven and gray yellow, sometimes black small points can be seen, and the yellow cutin ring is wound around the periphery; often accompanied by different levels of pain, severely affecting the quality of life of the patient.
Modern medicine believes that HPV interferes with the cytoplasmic cell cycle in order to complete its life cycle, keeping it replicating and delaying the natural death of the cell. Because the keratinocyte is infected by the HPV and then the cells cannot be pathologically dead or dissolved, the infection part lacks inflammatory reaction in most of the HPV infection period, so corresponding inflammatory factors are lacked, antigen presenting cells are difficult to activate at the pathological part, the transmission of immune signals cannot be established, and effective immune response is difficult to cause, thereby causing the persistent infection of the virus.
The existing treatment methods which are commonly used clinically are mostly physical therapies for directly removing the exogenic warts, the treatment methods have the advantage of simple operation, but only can eliminate skin and mucosa neoplasms, and viruses positioned on a basal cell layer are difficult to effectively remove and cannot achieve the radical effect; such treatments are difficult to apply to subclinical infected individuals who have a topical viral infection of the skin and mucous membranes, but do not have a neoplastic formation. In addition, it is very difficult to treat the patients with high wart number or low immune function because of its destructive and invasive properties. The treatment course of the immunomodulator is uncertain in curative effect, and the clinical application and treatment cost of the antiviral drugs and vaccines is high, so that the immunomodulator is limited to be widely used.
Plantar wart belongs to the categories of 'arrow, slurred cattle and' pustule 'in the field of traditional Chinese medicine science, and is first seen in the prescription for fifty-two diseases'. The disease is characterized by keratotic lesions, with rough and uneven center and grayish yellow color, surrounded by yellow keratose rings, often accompanied by different levels of tenderness. Combining the clinical manifestations of the patients, the pathogenic wind-heat attacking the skin is the external cause; anger mobilizes liver fire, liver exuberance and blood dryness, muscle and tendon qi is not good and skin is not moist, and local qi stagnation and blood stasis are internal causes; in addition, trauma and friction are often the causes of this disease. The "Lingshu & Jing Mai" (Ling Shu & Jing Mai) considers that: the difference of the hand sun is that the person with the name of erecting … … is hazy when the person with the hand sun is virtual, namely warts; ming dynasty Chen Shi Gong (orthodox department of surgery): ' withered tendon and arrow treats liver injury due to depression, and liver failing to nourish and nourish, so that tendon and qi are exogenic; ming Dynasty Xuehe "the pivot of surgery": wart is caused by liver and gallbladder shaoyang channel, wind-heat and blood dryness, or liver-qi obstruction. Liver heat and water are dry, kidney qi is not good, so essence is lost and tendons are contracture. The treatment principle is to clear away heat and toxic material, soften hardness and dissipate stagnation, activate blood and resolve stasis.
The traditional Chinese medicine is decocted, and the treatment mode of soaking the affected part while the traditional Chinese medicine is hot can directly reach the affected part; can soften the stratum corneum of the skin and enhance the absorption of the skin to the medicine, thereby achieving the purpose of treatment; the external washing treatment mode is particularly suitable for the application of the ultra-conventional oral dosage medicament, and gastrointestinal discomfort or other adverse reactions caused by the oral medicament are avoided while the curative effect is enhanced. Modern researches also show that HPV dies in 15 minutes at the temperature of more than 42 ℃, and the traditional Chinese medicine can effectively kill viruses at the affected part when being used externally; according to the meridian theory of traditional Chinese medicine, three yin of feet and three yang of feet respectively start and stop and are connected with the collaterals of feet, and the foot acupuncture points can be stimulated by warm heat by using traditional Chinese medicine soaking and washing to regulate qi activity. In conclusion, the traditional Chinese medicine external treatment method has the functions of local treatment and overall regulation, is simple, convenient, safe, effective, low in cost, free of wound and pain, and is more easily accepted by patients.
The powder is taken as a dosage form, so that the arrangement of atoms and molecules of medicinal materials cannot be changed, the material basis, the four flavors, the five flavors and the functional indications cannot be changed, and on the contrary, the absorption and the utilization of the medicine are greatly increased; the surface area of the powder is increased, the porosity is increased, and the medicine can be better dispersed and dissolved in the solvent; in addition, the powder preparation can be directly brewed with warm water, and is convenient and quick; the decoction can be carried out, the surface area of the particles of the powder is increased, the decoction can be completed in a very short time, and the problem that the drug property evaporates along with the water vapor in the decoction process is effectively reduced. Based on the reasons, the invention provides the external traditional Chinese medicine for treating the plantar wart.
Disclosure of Invention
The invention aims to provide an external traditional Chinese medicine for treating plantar wart with small side effect, safety and effectiveness and a preparation method thereof.
The specific technical scheme is as follows:
an external traditional Chinese medicine for treating verruca plantaris comprises the following raw material medicines in parts by weight: 5-10 parts of folium artemisiae argyi, 5-10 parts of isatis root, 6-9 parts of radix sophorae flavescentis, 6-9 parts of curcuma zedoary, 10-15 parts of rhizoma smilacis glabrae, 10-15 parts of purslane, 6-9 parts of safflower, 6-9 parts of peach kernel, 10-15 parts of folium isatidis, 10-15 parts of spina gleditsiae and 10-15 parts of scouring rush.
Further, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 10 parts of folium artemisiae argyi, 10 parts of isatis root, 9 parts of radix sophorae flavescentis, 9 parts of curcuma zedoary, 15 parts of rhizoma smilacis glabrae, 10 parts of purslane, 9 parts of safflower, 9 parts of peach kernel, 10 parts of folium isatidis, 10 parts of spina gleditsiae and 10 parts of scouring rush.
In the formula of the invention, the isatis root and the dyers woad leaf are mutually reinforced, have the effects of clearing heat and removing toxicity, are monarch drugs and are common traditional Chinese medicines for clinically treating virus infectious diseases. It is indicated for viral wart because it is both heat and toxic. The Chinese materia medica prescription records: isatis root is indicated for mania due to epidemic heat-toxicity, wind-heat macula, carbuncle and ulcer with swelling and pain … …, and it is advisable to smash blue leaves into juice for those with heat and toxicity.
Peach kernel, safflower, spina gleditsiae and rhizoma zedoariae are ministerial drugs, and the peach kernel, the safflower and the spina gleditsiae have the effects of promoting blood circulation, removing blood stasis and dissipating stagnation, improving peripheral tissue microcirculation, promoting skin metabolism, preventing wart hyperplasia and softening cutin; zedoary can break qi and promote blood circulation, remove food retention and alleviate pain, and has the effect of promoting blood circulation, removing blood stasis and dissipating stagnation.
Purslane and rhizoma smilacis glabrae clear away heat and toxic materials, and scouring rush dispels wind and heat; the lightyellow sophora root is bitter in taste and has the effects of clearing heat and drying dampness, killing insects and promoting urination, and the four medicines are adjuvant medicines and can reduce foot sweating.
The folium artemisiae argyi plays a role in inducing menstruation in the formula: folium artemisiae argyi is warm in nature and pungent in smell, can operate all channels, warm qi and blood, and regulate the functions of the body, recorded in compendium of materia Medica: moxibustion with moxa for treating various diseases, strengthening yang, activating meridians, promoting qi and blood.
Modern pharmacological research finds that the isatis root and the dyers woad leaf have stronger killing or inhibiting effect on various viruses; the dyers woad leaf has the function of improving the immunity of the organism; peach kernel and safflower, improving peripheral tissue microcirculation, promoting skin metabolism, preventing wart hyperplasia and softening cutin.
The folium Artemisiae Argyi has antiviral, immunity enhancing, antipyretic, and tranquilizing effects; the property of moxa can permeate into body through body surface to play a therapeutic role. The silicate and tannin contained in herba Equiseti hiemalis have astringent, antiinflammatory, and hemostatic effects on contact parts. The decoction is washed and soaked outside and used internally and externally to achieve the effects of clearing heat and removing toxicity, promoting blood circulation to remove blood stasis, and softening hardness to dissipate stagnation. From modern medicine, the recipe has the functions of resisting virus and strengthening immunity, so that it has high curative effect.
The dosage form of the external traditional Chinese medicine for treating verruca plantaris is any one of decoction, granules, powder and paste.
The invention relates to a preparation method of an external traditional Chinese medicine for treating plantar wart, which comprises the following steps:
the above medicinal materials are placed in an oven for drying at 80 ℃ for 30 minutes, after removing impurities, the medicinal materials are crushed into fine powder by a 40-mesh sieve, the medicinal powder is placed in a groove-shaped mixer for mixing uniformly, and then the mixture is granulated, and the medicinal powder is packaged into lotion with 9.0 g/bag by a medicinal powder packaging machine. And packaging, 6 bags per bag x 9.0 g/bag (50 g/bag).
Compared with the prior art, the invention has the beneficial effects that:
the external traditional Chinese medicine for treating plantar wart is a pure traditional Chinese medicine preparation, has the advantages of simple formula, external treatment, high safety, no side effect, low cost and strong practicability.
Drawings
FIG. 1 is a state diagram before treatment in example 1;
FIG. 2 is a state diagram after the treatment in example 1;
FIG. 3 is a state diagram before treatment in example 2;
FIG. 4 is a state diagram after the treatment in example 2.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to specific embodiments.
Example 1
Patient, a woman, age 36, clinic number: 9047300 the first diagnosis in Zhejiang province is made in 2019, 1 month, 7 days, because of "the skin of the right toe is born for 3 months and the pain is increased by 1 month". PE: 3-4 brown skin neoplasms with the size of soybean can be seen on the right toe part, the skin is hard, 2 of the skin neoplasms are fused into pieces, and skin wrinkles on the neoplasms disappear.
And (3) Western diagnosis: plantar wart
The traditional Chinese medicine formula of the invention is externally used for treating
After treatment, patients were outpatient and follow-up on the following dates: 2019.01.14, 2019.01.28, 2019.02.18, 2019.03.04, 2019.03.18, 2019.04.04 and 2019.04.26, the skin damage is gradually improved.
Example 2
The patient, 63 years old, in clinic No. 8214287, was first diagnosed in Zhejiang province in 2016 (1 month and 15 days) for pain associated with skin neoplasm in both toes. PE: the right toe part can be seen with a yellowish-brown skin neoplasm from dozens of mung beans to soybeans, the skin is hard, most of the skin neoplasm is fused into a sheet, skin lines at the skin lesion disappear, and the squeeze pain (+) is caused.
And (3) Western diagnosis: plantar wart
The traditional Chinese medicine formula of the invention is externally used for treating
After treatment, patients were outpatient and follow-up on the following dates: 2016.01.22, 2016.02.26, 2016.03.11
The skin damage is gradually improved.
The above description is only a preferred embodiment of the present invention, and the scope of the present invention is not limited thereto, and any simple modifications or equivalent substitutions of the technical solutions that can be obviously obtained by those skilled in the art within the technical scope of the present invention are within the scope of the present invention.
Claims (4)
1. An external traditional Chinese medicine for treating verruca plantaris is characterized by comprising the following raw material medicines in parts by weight: 5-10 parts of folium artemisiae argyi, 5-10 parts of isatis root, 6-9 parts of radix sophorae flavescentis, 6-9 parts of curcuma zedoary, 10-15 parts of rhizoma smilacis glabrae, 10-15 parts of purslane, 6-9 parts of safflower, 6-9 parts of peach kernel, 10-15 parts of folium isatidis, 10-15 parts of spina gleditsiae and 10-15 parts of scouring rush.
2. The external traditional Chinese medicine for treating plantar wart according to claim 1, which is characterized by comprising the following raw material medicines in parts by weight: comprises the following raw material medicines in parts by weight: 10 parts of folium artemisiae argyi, 10 parts of isatis root, 9 parts of radix sophorae flavescentis, 9 parts of curcuma zedoary, 15 parts of rhizoma smilacis glabrae, 10 parts of purslane, 9 parts of safflower, 9 parts of peach kernel, 10 parts of folium isatidis, 10 parts of spina gleditsiae and 10 parts of scouring rush.
3. The external traditional Chinese medicine for treating plantar wart as claimed in claim 1, wherein the dosage form of the external traditional Chinese medicine for treating plantar wart is any one of decoction, granules, powder and paste.
4. A method for preparing an externally applied traditional Chinese medicine for treating plantar wart as claimed in claim 1, comprising the following steps: weighing the raw materials, placing the raw materials in an oven for drying at 80 ℃ for 30 minutes, removing impurities, crushing the raw materials into fine powder by a 40-mesh sieve, placing the fine powder in a trough mixer for uniformly mixing, granulating, packaging the powder into 9.0 g/bag of lotion by a powder packaging machine, and placing the lotion into packages, wherein 6 bags/bag is multiplied by 9.0 g/bag, and 50 g/bag.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114344399A (en) * | 2021-12-02 | 2022-04-15 | 郭尚明 | Chinese medicinal compound preparation for treating verruca plantaris and preparation method thereof |
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