CN110721269A - Chinese wolfberry composite oral liquid and preparation method thereof - Google Patents

Chinese wolfberry composite oral liquid and preparation method thereof Download PDF

Info

Publication number
CN110721269A
CN110721269A CN201911210261.5A CN201911210261A CN110721269A CN 110721269 A CN110721269 A CN 110721269A CN 201911210261 A CN201911210261 A CN 201911210261A CN 110721269 A CN110721269 A CN 110721269A
Authority
CN
China
Prior art keywords
parts
oral liquid
chinese herbal
herbal medicine
medlar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911210261.5A
Other languages
Chinese (zh)
Inventor
程渊
郭振忠
胡维岗
方宝红
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ningxia Baofeng Ecological Ranch Co Ltd
Original Assignee
Ningxia Baofeng Ecological Ranch Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ningxia Baofeng Ecological Ranch Co Ltd filed Critical Ningxia Baofeng Ecological Ranch Co Ltd
Priority to CN201911210261.5A priority Critical patent/CN110721269A/en
Publication of CN110721269A publication Critical patent/CN110721269A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a medlar composite oral liquid and a preparation method thereof. The invention discloses a medlar composite oral liquid which comprises the following components in parts by weight: 500-600 parts of Chinese wolfberry clear juice, 500-600 parts of Chinese herbal medicine extract and 50-100 parts of fructo-oligosaccharide. The invention relates to a medlar composite oral liquid and a preparation method thereof, and the oral liquid is prepared by blending, clarifying and sterilizing medlar clear juice and Chinese herbal medicine extract. The invention combines the anti-fatigue, kidney-tonifying, essence-enriching, liver-nourishing, eyesight-improving and immunity-regulating functions of the medlar clear juice with the functions of activating male hormones and strengthening physique of various Chinese herbal medicines. The oral liquid is brown transparent liquid, is sweet and slightly bitter, has unique flavor of fructus Lycii mixed with various Chinese herbal medicines, and has refreshing taste and strong herbal medicine flavor. Is rich in various organic acids, compound polysaccharides, amino acids, vitamins and alkaloid glycosides, has good antifatigue effect, and is effective in invigorating kidney, strengthening waist, exciting hematopoiesis, promoting male sexual function, and enhancing organism activity, and can be directly drunk as oral liquid.

Description

Chinese wolfberry composite oral liquid and preparation method thereof
Technical Field
The invention relates to a medlar composite oral liquid and a preparation method thereof.
Background
With the increase of the pressure of work and life, the health condition of people is influenced to a certain extent, the male sexual dysfunction becomes a common disease for adult men, and the incidence rate is obviously increased in recent years. With the attention of people on physical health, some health care products and medicines are used for regulation. However, most of the existing products for enhancing and improving male sexual function are medicines or food with illegally added medicines, and although the effect is quick, the products have the defects of medicine dependence, side effect and the like. The sexual function problem troubling men is solved by searching effective and safe medicinal and edible homologous resources from natural Chinese herbal medicines to regulate the endocrine system of the body, and the drug dependence of drug side effects is avoided, so that the problem which needs to be solved generally is solved.
The medlar is a traditional famous and precious Chinese medicinal material and an important economic crop in China, and is recorded in compendium of materia Medica: medlar, tonifying kidney and producing essence, nourishing liver, improving eyesight, strengthening essence and bone, relieving fatigue, changing color, whitening, improving eyesight and calming nerves and prolonging life. Recent medical research finds that the medlar has the effects of resisting aging, enhancing immunity and inhibiting the growth of cancer cells. The medlar mainly contains two active ingredients of polysaccharide and flavonoid, and also contains various vitamins, organic acid, amino acid, carotene, zeaxanthin and the like, has the effects of nourishing liver and kidney, benefiting essence and improving eyesight, and also has the effects of reducing blood pressure, reducing blood sugar, reducing blood fat, resisting tumors, improving human immunity and delaying senility, thereby being an excellent natural health food source.
The Chinese herbal medicine extract extracted at low temperature by compounding the clear wolfberry juice can not only retain the nutrient components and activity of the wolfberry, but also avoid the damage of the nutrient components and the active components of the wolfberry caused by decoction and extraction of solid powdery wolfberry products with the application numbers of CN201310492599.0 and CN 201310296696.2. In addition, the Chinese herbal medicine extract is compounded, so that the Chinese wolfberry composite oral efficacy can be balanced and enhanced. Meanwhile, the fructo-oligosaccharide can improve intestinal flora and promote intestinal health and weight control.
Disclosure of Invention
The invention aims to provide the medlar composite oral liquid which has rich nutrition, enhances the sexual function of men and tastes sweet, fragrant and slightly bitter.
The medlar composite oral liquid is characterized by comprising the following components in parts by weight: 500-600 parts of Chinese wolfberry clear juice, 500-600 parts of Chinese herbal medicine extract and 50-100 parts of fructo-oligosaccharide.
Preferably, the medlar composite oral liquid comprises the following components in parts by weight: 550 parts of medlar clear juice, 550 parts of Chinese herbal medicine extract and 55 parts of fructo-oligosaccharide.
Preferably, the medlar composite oral liquid is prepared by centrifuging medlar raw juice for 6-10min at 6000-10000rad/min, taking supernatant and then filtering the supernatant by a cross-flow filter with the aperture of 0.1-0.2 mu m.
Preferably, the Chinese herbal medicine extract is prepared by extracting the following Chinese herbal medicines in parts by weight: 400-500 parts of cistanche, 400-500 parts of cynomorium songaricum, 200-300 parts of ginseng, 200-300 parts of morinda officinalis, 200-300 parts of epimedium, 100-200 parts of cherokee rose fruit, 100-200 parts of rhodiola rosea, 50-100 parts of astragalus mongholicus, 50-100 parts of lily, 50-100 parts of polygonum multiflorum, 50-100 parts of liquorice, 50-100 parts of radix puerariae, 50-100 parts of rhizoma polygonati, 50-100 parts of orobanum, 50-100 parts of lotus seed and 50-100 parts of poria cocos.
Preferably, the Chinese herbal medicine extracting solution is prepared by extracting the following Chinese herbal medicines in parts by weight: 450 parts of cistanche, 450 parts of cynomorium songaricum, 250 parts of ginseng, 250 parts of morinda officinalis, 250 parts of epimedium, 150 parts of cherokee rose fruit, 150 parts of rhodiola rosea, 75 parts of astragalus membranaceus, 75 parts of lily, 75 parts of polygonum multiflorum, 75 parts of liquorice, 75 parts of kudzuvine root, 75 parts of polygonatum sibiricum, 75 parts of broomrape, 75 parts of lotus seed and 75 parts of poria cocos.
Preferably, the preparation method of the Chinese herbal medicine extracting solution comprises the following steps:
(1) crushing: mixing the Chinese herbal medicines according to the weight part of the formula, and then crushing to 40-60 meshes to obtain Chinese herbal medicine powder;
(2) extraction: adding purified water into the Chinese herbal medicine powder according to a material-water ratio of 1: 5-10, soaking for 8-12 h at 45-55 ℃, and filtering residues through 100-200-mesh filter cloth to obtain a crude Chinese herbal medicine extract;
(3) and (3) microfiltration: filtering the crude extractive solution with cross-flow filter with pore diameter of 0.1-0.2 μm to obtain the extractive solution.
Preferably, the wolfberry composite oral liquid is food-grade F55 liquid fructo-oligosaccharide.
A preparation method of a medlar composite oral liquid comprises the following steps:
(1) blending: according to the weight portion recorded in claim 1, uniformly mixing the clear wolfberry juice, the Chinese herbal medicine extract and the fructo-oligosaccharide;
(2) clarification: standing the mixed solution obtained in the step (1) at-5-0 ℃ for 2-4 days, and then filtering by adopting a cross flow filter with the aperture of 0.1-0.2 mu m to obtain the medlar composite oral liquid;
(3) and (3) sterilization: and (3) bottling and sterilizing the medlar compound oral liquid obtained in the step (2) to obtain a finished medlar compound oral liquid product.
Preferably, the sterilization in the step (3) refers to heating for 20-30min at 85-90 ℃.
The invention provides a medlar composite oral liquid and a preparation method thereof. 1. The pure natural health-care food does not contain any hormone or chemical medicine, and can reduce the influence of the hormone or the chemical medicine on the health of a human body in the taking process; 2. the Chinese herbal medicines are reasonable in design and compatible with each other, have exact and obvious treatment effect on enhancing the male sexual function, are quick in effect, safe and free of side effect; 3. focusing on overall nursing, and conditioning the whole body of a human body to be in an optimal state while activating male hormones; 4. the Chinese herbal medicine extracting solution is extracted at low temperature, the extraction temperature is controlled to be 40-50 ℃, compared with a decoction extraction method, the method reduces damage to active ingredients of the medicine, and the obtained extract has better medicinal activity and also has the advantages of high efficiency, simplicity and convenience in operation, energy conservation and the like; 5. similar medicaments in the market are basically powder or capsules, and the product is oral liquid, is convenient to drink and is easy to popularize.
Detailed Description
The invention aims to provide a medlar composite oral liquid and a preparation method thereof. The present invention is described in further detail with reference to specific embodiments, which are given for the purpose of illustration only and are not intended to limit the scope of the invention.
Example 1:
(1) preparing the clear wolfberry juice: centrifuging fructus Lycii juice at 10000rad/min for 10min, collecting supernatant, and filtering with cross-flow filter with pore diameter of 0.1 μm.
(2) Preparing a Chinese herbal medicine extracting solution:
crushing: taking 450 parts of cistanche, 450 parts of cynomorium songaricum, 250 parts of ginseng, 250 parts of morinda officinalis, 250 parts of epimedium, 150 parts of cherokee rose fruit, 150 parts of rhodiola rosea, 75 parts of astragalus membranaceus, 75 parts of lily, 75 parts of polygonum multiflorum, 75 parts of liquorice, 75 parts of kudzuvine root, 75 parts of rhizoma polygonati, 75 parts of broomrape, 75 parts of lotus seed and 75 parts of poria cocos according to parts by weight, mixing, and then crushing to 60 meshes to obtain Chinese herbal medicine powder;
extraction: adding purified water into the Chinese herbal medicine powder according to the material-water ratio of 1:10, soaking at 45 ℃ for 12h, and filtering residues by using 200-mesh filter cloth to obtain a Chinese herbal medicine crude extract;
and (3) filtering: the crude extract of Chinese herbal medicine is filtered by a cross-flow filter with pore size of 0.1 μm to obtain the Chinese herbal medicine extract.
(3) Preparing the medlar composite oral liquid:
blending: according to the weight parts, 550 parts of medlar clear juice, 550 parts of Chinese herbal medicine extract and 55 parts of food-grade F55 liquid fructo-oligosaccharide are mixed to obtain mixed liquid;
clarification: standing the mixed solution at-5 deg.C for 2 days, and filtering with cross-flow filter with pore diameter of 0.1 μm to obtain fructus Lycii composite oral liquid;
and (3) sterilization: bottling the obtained fructus Lycii composite oral liquid, heating at 90 deg.C for 30min, and sterilizing. And obtaining the finished product of the medlar composite oral liquid.
Example 2:
(1) preparing the clear wolfberry juice: collecting fructus Lycii juice 10000rad/min, centrifuging for 6min, collecting supernatant, and filtering with cross-flow filter with pore diameter of 0.2 μm.
(2) Preparing a Chinese herbal medicine extracting solution:
crushing: taking 500 parts of cistanche, 500 parts of cynomorium songaricum, 300 parts of ginseng, 200 parts of morinda officinalis, 300 parts of epimedium, 200 parts of cherokee rose fruit, 200 parts of rhodiola rosea, 100 parts of astragalus membranaceus, 100 parts of lily, 100 parts of polygonum multiflorum, 100 parts of liquorice, 100 parts of kudzuvine root, 100 parts of rhizoma polygonati, 100 parts of broomrape, 50 parts of lotus seed and 100 parts of poria cocos according to parts by weight, mixing, and then crushing to 60 meshes to obtain Chinese herbal medicine powder;
extraction: adding purified water into the Chinese herbal medicine powder according to the material-water ratio of 1:10, soaking at 55 deg.C for 12h, filtering with 200 mesh filter cloth to remove residue to obtain crude extract of Chinese herbal medicine;
and (3) filtering: the crude extract of Chinese herbal medicine is filtered by a cross-flow filter with pore size of 0.2 μm to obtain the extract of Chinese herbal medicine.
(3) Preparing the medlar composite oral liquid:
blending: mixing 600 parts of Chinese wolfberry clear juice, 500 parts of Chinese herbal medicine extracting solution and 50 parts of food-grade F55 liquid fructo-oligosaccharide according to parts by weight to obtain a mixed solution;
clarification: standing the mixed solution at-5 deg.C for 4 days, and filtering with cross-flow filter with pore diameter of 0.2 μm to obtain fructus Lycii composite oral liquid;
and (3) sterilization: bottling the obtained fructus Lycii composite oral liquid, heating at 85 deg.C for 30min, and sterilizing. And obtaining the finished product of the medlar composite oral liquid.
Example 3:
(1) preparing the clear wolfberry juice: collecting fructus Lycii juice 10000rad/min, centrifuging for 6min, collecting supernatant, and filtering with cross-flow filter with pore diameter of 0.2 μm.
(2) Preparing a Chinese herbal medicine extracting solution:
crushing: taking 500 parts of cistanche, 400 parts of cynomorium songaricum, 300 parts of ginseng, 200 parts of morinda officinalis, 200 parts of epimedium, 200 parts of cherokee rose fruit, 100 parts of rhodiola rosea, 100 parts of astragalus membranaceus, 100 parts of lily, 50 parts of polygonum multiflorum, 100 parts of liquorice, 100 parts of kudzuvine root, 100 parts of rhizoma polygonati, 100 parts of broomrape, 100 parts of lotus seed and 50 parts of poria cocos according to parts by weight, mixing, and then crushing to 60 meshes to obtain Chinese herbal medicine powder;
extraction: adding purified water into the Chinese herbal medicine powder according to the material-water ratio of 1:5, soaking at 55 deg.C for 12h, filtering with 100 mesh filter cloth to remove residue to obtain crude extract of Chinese herbal medicine;
and (3) filtering: the crude extract of Chinese herbal medicine is filtered by a cross-flow filter with pore size of 0.2 μm to obtain the extract of Chinese herbal medicine.
(3) Preparing the medlar composite oral liquid:
blending: mixing 600 parts of Chinese wolfberry clear juice, 500 parts of Chinese herbal medicine extracting solution and 100 parts of food-grade F55 liquid fructo-oligosaccharide according to parts by weight to obtain a mixed solution;
clarification: standing the mixed solution at 0 deg.C for 2 days, and filtering with cross-flow filter with pore diameter of 0.2 μm to obtain fructus Lycii composite oral liquid;
and (3) sterilization: bottling the obtained fructus Lycii composite oral liquid, heating at 90 deg.C for 20min, and sterilizing. And obtaining the finished product of the medlar composite oral liquid.

Claims (9)

1. The Chinese wolfberry composite oral liquid is characterized by comprising the following components in parts by weight: 500-600 parts of Chinese wolfberry clear juice, 500-600 parts of Chinese herbal medicine extract and 50-100 parts of fructo-oligosaccharide.
2. The medlar composite oral liquid of claim 1, which comprises the following components in parts by weight: 550 parts of medlar clear juice, 550 parts of Chinese herbal medicine extract and 55 parts of fructo-oligosaccharide.
3. The compound oral liquid of claim 1 or 2, wherein the clear juice of Lycium barbarum is obtained by centrifuging raw juice of Lycium barbarum at 6000-10000rad/min for 6-10min, collecting the supernatant, and filtering with a cross-flow filter having a pore size of 0.1-0.2 μm.
4. The medlar composite oral liquid of claim 1 or 2, wherein the Chinese herbal medicine extract is prepared by extracting the following Chinese herbal medicines in parts by weight: 400-500 parts of cistanche, 400-500 parts of cynomorium songaricum, 200-300 parts of ginseng, 200-300 parts of morinda officinalis, 200-300 parts of epimedium, 100-200 parts of cherokee rose fruit, 100-200 parts of rhodiola rosea, 50-100 parts of astragalus mongholicus, 50-100 parts of lily, 50-100 parts of polygonum multiflorum, 50-100 parts of liquorice, 50-100 parts of radix puerariae, 50-100 parts of rhizoma polygonati, 50-100 parts of orobanum, 50-100 parts of lotus seed and 50-100 parts of poria cocos.
5. The compound wolfberry oral liquid of claim 1, 2 or 4, wherein the Chinese herbal medicine extract is prepared by extracting the following raw materials in parts by weight: 450 parts of cistanche, 450 parts of cynomorium songaricum, 250 parts of ginseng, 250 parts of morinda officinalis, 250 parts of epimedium, 150 parts of cherokee rose fruit, 150 parts of rhodiola rosea, 75 parts of astragalus membranaceus, 75 parts of lily, 75 parts of polygonum multiflorum, 75 parts of liquorice, 75 parts of kudzuvine root, 75 parts of polygonatum sibiricum, 75 parts of broomrape, 75 parts of lotus seed and 75 parts of poria cocos.
6. The compound wolfberry oral liquid of claim 1, 2, 4 or 5, wherein the preparation method of the Chinese herbal medicine extract comprises the following steps:
(1) crushing: mixing the Chinese herbal medicines in parts by weight according to claim 4, and then crushing to 40-60 meshes to obtain Chinese herbal medicine powder;
(2) extraction: adding purified water into the Chinese herbal medicine powder according to a material-water ratio of 1: 5-10, soaking for 8-12 h at 45-55 ℃, and then filtering residues by using 100-200-mesh filter cloth to obtain a crude Chinese herbal medicine extract;
(3) and (3) microfiltration: filtering the crude extractive solution with cross-flow filter with pore diameter of 0.1-0.2 μm to obtain the extractive solution.
7. The wolfberry fruit composite oral liquid as claimed in claim 1, 2, 4 or 5, wherein the fructo-oligosaccharide is food grade F55 type liquid fructo-oligosaccharide.
8. A preparation method of a medlar composite oral liquid is characterized by comprising the following steps:
(1) blending: according to the weight portion recorded in claim 1, uniformly mixing the clear wolfberry juice, the Chinese herbal medicine extract and the fructo-oligosaccharide;
(2) clarification: standing the mixed solution obtained in the step (1) at-5-0 ℃ for 2-4 days, and then filtering by adopting a cross-flow filter with the aperture of 0.1-0.2 mu m to obtain the medlar composite oral liquid;
(3) and (3) sterilization: and (3) bottling and sterilizing the medlar compound oral liquid obtained in the step (2) to obtain a finished medlar compound oral liquid product.
9. The preparation method of the wolfberry composite oral liquid as claimed in claim 8, wherein the sterilization in the step (3) is heating at 85-90 ℃ for 20-30 min.
CN201911210261.5A 2019-12-02 2019-12-02 Chinese wolfberry composite oral liquid and preparation method thereof Pending CN110721269A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911210261.5A CN110721269A (en) 2019-12-02 2019-12-02 Chinese wolfberry composite oral liquid and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911210261.5A CN110721269A (en) 2019-12-02 2019-12-02 Chinese wolfberry composite oral liquid and preparation method thereof

Publications (1)

Publication Number Publication Date
CN110721269A true CN110721269A (en) 2020-01-24

Family

ID=69226284

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911210261.5A Pending CN110721269A (en) 2019-12-02 2019-12-02 Chinese wolfberry composite oral liquid and preparation method thereof

Country Status (1)

Country Link
CN (1) CN110721269A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1768811A (en) * 2005-11-04 2006-05-10 胡正岳 Kidney-replenishing yang-invigorating medicine and its preparing method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1768811A (en) * 2005-11-04 2006-05-10 胡正岳 Kidney-replenishing yang-invigorating medicine and its preparing method

Similar Documents

Publication Publication Date Title
CN103689177B (en) Traditional Chinese medicine coffee beverage with health-care effect and preparation method of traditional Chinese medicine coffee beverage
CN107811249B (en) Preparation method of red date and ginseng health-care jelly
CN102827750A (en) Maca health care liquor for improving organism immunity and sexuality
CN103191332A (en) Composition and health-care product with stomach-invigorating and digestion-promoting functions
CN111956753B (en) Medicinal and edible traditional Chinese medicine composition as well as preparation method and application thereof
CN103504444A (en) Method for preparing mythic fungus and dictyophora phalloidea solid beverage
CN112057551A (en) Composition with functions of nourishing yin and tonifying kidney and preparation method and application thereof
CN105543052A (en) Okra wine with health preserving and kidney tonifying functions and preparing method thereof
CN105166235A (en) Qi-blood tonifying health tea capable of reducing hyperlipidemia, hypertension and hyperglycemia and preparation method thereof
CN110917291A (en) Composition with function of improving immunity and preparation method and application thereof
CN103462022A (en) Cordyceps militaris nourishing paste and preparation method thereof
CN105707598A (en) Plant drink for dispelling alcohol effects and preparation method thereof
CN104824766A (en) Persimmon juice beverage and preparation method thereof
CN107751993A (en) A kind of antifatigue cream taste and preparation method thereof
CN110151983A (en) A kind of Chinese materia medica preparation and preparation method thereof for tonifying Qi of the kidney
CN103055157B (en) Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof
CN102604802B (en) Preparation method of originally ecological bamboo-germanium nutritional wine
CN103798435B (en) Fructus Citri Sarcodactylis Folium Mori Fructus Lycii tea and preparation method thereof
CN108684992A (en) A kind of alcohol-decomposing beverage of plant formula and preparation method thereof of energy Quick sobering
CN105831327A (en) Snow chrysanthemum herbal tea drink, and preparation method and application thereof
CN101176756A (en) Mulberry schizandrae honey oral liquid and technique of preparing the same
CN110721269A (en) Chinese wolfberry composite oral liquid and preparation method thereof
CN102613628B (en) Original ecological coconut germanium juice and producing method thereof
CN111543526A (en) Inonotus obliquus and cordyceps sinensis health-care tea capable of tonifying liver, tonifying kidney and dispelling wind
CN110651858A (en) Bagged tea for reducing uric acid and relieving gout and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20200124