CN110721008A - Naked degradable abdominal aorta covered stent and preparation method thereof - Google Patents
Naked degradable abdominal aorta covered stent and preparation method thereof Download PDFInfo
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- CN110721008A CN110721008A CN201910955419.5A CN201910955419A CN110721008A CN 110721008 A CN110721008 A CN 110721008A CN 201910955419 A CN201910955419 A CN 201910955419A CN 110721008 A CN110721008 A CN 110721008A
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- 210000000702 aorta abdominal Anatomy 0.000 title claims abstract description 114
- 238000002360 preparation method Methods 0.000 title description 7
- 210000000709 aorta Anatomy 0.000 claims abstract description 29
- 239000000956 alloy Substances 0.000 claims abstract description 18
- 229920006267 polyester film Polymers 0.000 claims abstract description 17
- 229910000861 Mg alloy Inorganic materials 0.000 claims abstract description 16
- 229910000640 Fe alloy Inorganic materials 0.000 claims abstract description 14
- 239000000463 material Substances 0.000 claims abstract description 13
- 239000010935 stainless steel Substances 0.000 claims abstract description 10
- 229910001000 nickel titanium Inorganic materials 0.000 claims abstract description 4
- 229910001220 stainless steel Inorganic materials 0.000 claims abstract description 4
- 230000003187 abdominal effect Effects 0.000 claims description 15
- 238000005452 bending Methods 0.000 claims description 13
- 238000004804 winding Methods 0.000 claims description 9
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 6
- 229910001256 stainless steel alloy Inorganic materials 0.000 claims description 6
- 241001573881 Corolla Species 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 238000003466 welding Methods 0.000 claims description 3
- 229910001021 Ferroalloy Inorganic materials 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 3
- 210000001367 artery Anatomy 0.000 abstract description 13
- 208000027418 Wounds and injury Diseases 0.000 description 15
- 241000251468 Actinopterygii Species 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 208000002251 Dissecting Aneurysm Diseases 0.000 description 2
- 206010002895 aortic dissection Diseases 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 206010053649 Vascular rupture Diseases 0.000 description 1
- 208000007474 aortic aneurysm Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 230000002966 stenotic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
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- Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Prostheses (AREA)
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Abstract
The invention discloses a naked-region degradable abdominal aorta covered stent, which comprises a fixed stent and a plurality of wavy abdominal aorta stent units, wherein each abdominal aorta stent unit is wound into a ring shape, and the plurality of annular wound abdominal aorta stent units are sequentially arranged to form an abdominal aorta stent; the fixed support is wavy and wound into a ring, the fixed support is provided with a naked area part and a connecting part which are integrally formed and respectively positioned at two ends of the fixed support wound into the ring, the connecting part is arranged at one end of the abdominal aorta support, and the connecting part and the abdominal aorta support are coated with polyester films together; the bare area part is made of magnesium alloy or iron alloy material, and the abdominal aorta stent is made of medical stainless steel material or nickel-titanium alloy material. The aorta abdominalis covered stent of the invention can be degraded by itself in the naked area, thus not only satisfying the fixed use of the stent in the early stage, but also avoiding the scratch of the artery wall caused by long-time use.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a naked degradable abdominal aorta covered stent and a preparation method thereof.
Background
Currently used abdominal aorta covered stent generally protrudes a bare area (a metal grid stent without a polyester film) made of metal alloy at the end part of the stent, or a barb is arranged on the outer side wall of the stent, so that the stent can be stably placed in an artery at the initial stage of an operation, however, in the two fixing modes, the bare area and the barb are always kept in the artery, and in the course of time, certain damage can be caused to the artery of a patient, the rupture of the intima and media of the aorta is caused, and a new aortic dissection appears. At present, degradable bare stents are available in treatment of arteriolar stenotic lesions such as coronary artery and the like, but aortic stents are basically covered stents which mainly play a role in isolating aortic aneurysm or aortic dissection in a cavity, so that the stent with a membrane part has a permanent supporting function and is not suitable for degradable materials. And the naked area part only plays a role in fixing the stent in the early stage of stent placement, and prevents the stent from backward displacement under the impact of blood flow. After 1-3 months of operation, vascular endothelial cells begin to slowly grow into the stent, wrap the front ends of the bare area and the covered stent, the stent can not shift any more, the bare area of the stent also loses effect, but the risk of vascular rupture is caused because the bare area continuously stimulates the vascular wall, and the bare area blocks the renal artery opening, thereby affecting the long-term effect.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a degradable abdominal aorta covered stent in a bare area and a preparation method thereof, wherein the bare area part can be automatically degraded, so that the fixed use of the stent in the early stage can be met, and the scratch of the arterial wall caused by long-time use can be avoided.
In order to achieve the purpose, the invention adopts the technical scheme that:
a naked-region degradable abdominal aorta covered stent comprises a fixed stent and a plurality of wavy abdominal aorta stent units, wherein each abdominal aorta stent unit is wound into a ring shape, the plurality of annular abdominal aorta stent units are sequentially arranged to form the abdominal aorta stent, the abdominal aorta stent comprises a main stent positioned at the front end of the abdominal aorta stent and two branch stents positioned at the far ends of the abdominal aorta stent, the main stent is of a straight-tube structure, the outer diameter of the main stent is 20mm-30mm, and the outer diameter of each branch stent is 12mm-14 mm; the fixed support is wavy and wound into a ring, the fixed support is provided with a naked area part and a connecting part which are integrally formed and respectively positioned at two ends of the fixed support wound into the ring, the connecting part is arranged at one end of the abdominal aorta support, and the connecting part and the abdominal aorta support are coated with polyester films together; the naked area part of fixed bolster is magnesium alloy or ferroalloy material, the aorta abdominalis support is medical stainless steel material or nickel titanium alloy material.
In the structure, the aorta abdominalis covered stent consists of an aorta abdominalis stent and a fixed stent, a plurality of independent aorta abdominalis stent units in the aorta abdominalis stent are fixedly coated with the connecting part of the fixed stent through a polyester film to form the aorta abdominalis covered stent with a main stent and two branch stents, the bare area part of the fixed stent is exposed and used for fixing the aorta abdominalis covered stent, moreover, the naked area of the fixed stent is made of degradable magnesium alloy or iron alloy material, after the abdominal aorta covered stent is placed in a human body for a period of time, the main part of the aorta abdominalis covered stent is fused with the aorta abdominalis (which is fixed without an additional structure), the naked part which has the fixing function is gradually absorbed by the human body, and is degraded, compared with the traditional naked part which is not degradable and adopts a barb structure, the aorta abdominalis covered stent is prevented from being scratched on the artery wall caused by the human body for a long time.
Preferably, the length of the naked region is 10mm-15mm, so that the contact area between the naked region and the abdominal artery wall can be reduced while the sufficient connection stability is ensured, and further the scratch to the abdominal artery wall is reduced.
Preferably, the naked part is in a crown shape with the outer diameter of the front end larger than that of the rear end, and the arc center angle of the arc-shaped bent part of the naked part is 18-23 degrees.
The naked district portion of fixed bolster is the corolla form, and naked district portion is whole to be the structure of smooth outside bending, reducible fish tail to the abdominal aorta pipe wall, and the front end of naked district portion forms the convex structure, can make the support put into in the abdominal aorta more firm. The arc center angle of the bare area part is 18-23 degrees, so that the smoothness of the whole structure of the bare area part can be ensured, and meanwhile, the bare area part has enough strength.
Preferably, the minimum outer diameter of the connecting part wound in a ring shape is the same as the outer diameter of the abdominal aorta stent unit wound in a ring shape, and the difference between the maximum outer diameter of the bare area wound in a ring shape and the outer diameter of the abdominal aorta stent unit wound in a ring shape is 2mm-3mm, so that the protrusion height of the boss formed at the front end of the bare area is 1mm-1.5mm, and the contact fusion between the abdominal aorta covered stent and the abdominal aorta is not affected.
Preferably, the naked region part is provided with a barb which is arranged towards the distal end of the abdominal aorta stent and can prevent the abdominal aorta stent from sliding downwards.
The invention also provides a preparation method of the degradable abdominal aorta covered stent in the nude area, which adopts the technical scheme as follows:
a preparation method of a naked degradable abdominal aorta covered stent comprises the following steps:
s1, taking medical stainless steel or titanium alloy wire materials, bending the medical stainless steel or titanium alloy wire materials into a zigzag wavy abdominal aorta stent unit, and winding the abdominal aorta stent unit into a ring shape;
s2, sequentially arranging a plurality of annularly wound abdominal aorta stent units to form an abdominal aorta stent with a main stent and two branch stents;
s3, taking medical magnesium alloy or iron alloy material, bending the medical magnesium alloy or iron alloy material in a Z shape to form a wavy fixed support, and winding the fixed support into a ring shape;
s4, bending the naked area of the fixed stent to the outer side of the aorta abdominalis covered stent at an arc center angle of 18-23 degrees;
s5, welding barbs of magnesium alloy or iron alloy materials on the bare area part of the fixing support;
s6, winding the abdominal aorta stent unit and the fixed stent into a ring shape;
and S8, butting the connecting part of the fixed support with the front end of the abdominal aorta support, and coating the connecting part of the abdominal aorta support and the fixed support by adopting a polyester film to obtain the degradable abdominal aorta covered stent in the naked region.
Preferably, the length of the bare area of the fixing stent in step S4 is 10mm to 15 mm.
Preferably, the polyester film covers all the connecting parts of the fixing stent and the front end part of the polyester film covers the bare area part of the fixing stent in step S8.
The invention has the beneficial effects that:
1. the abdominal aorta of the fixed support is made of degradable magnesium alloy or iron alloy materials, after the abdominal aorta covered stent is placed into a human body for a period of time, the main body part of the abdominal aorta covered stent is fused with the abdominal aorta, the naked region part playing a role in fixing is gradually absorbed by the human body, degradation occurs, compared with the traditional naked region, the abdominal aorta covered stent is not degradable and adopts a barbed structure, and the scratch of the artery wall caused by the fact that the abdominal aorta covered stent is placed in the human body for a long time is avoided.
2. The length of the naked region is 10mm-15mm, so that the contact area between the naked region and the abdominal artery tube wall can be reduced while the sufficient connection stability is ensured, and further the scratch to the abdominal artery tube wall is reduced.
3. The naked district portion of fixed bolster is the corolla form, and naked district portion is whole to be the structure of smooth outside bending, reducible fish tail to the abdominal aorta pipe wall, and the front end of naked district portion forms the convex structure, can make the support put into in the abdominal aorta more firm. The arc center angle of the bare area part is 18-23 degrees, so that the smoothness of the whole structure of the bare area part can be ensured, and meanwhile, the bare area part has enough strength.
4. The difference value between the outer diameter of the front end of the naked area and the outer diameter of the abdominal aorta stent unit is 2mm-3mm, so that the height of the boss formed at the front end of the naked area is 1mm-1.5mm, and the contact fusion between the abdominal aorta covered stent and the abdominal aorta is not affected.
5. The naked area part is provided with a barb which is arranged towards the far end of the abdominal aorta bracket and can prevent the abdominal aorta bracket from sliding downwards.
Drawings
FIG. 1 is a first schematic structural diagram of a bare-area degradable aorta abdominalis covered stent according to an embodiment of the present invention;
FIG. 2 is an enlarged view taken at A in FIG. 1;
FIG. 3 is a schematic structural diagram II of a bare-area degradable aorta abdominalis covered stent according to an embodiment of the present invention;
FIG. 4 is a top view of a bare area degradable aorta abdominalis covered stent according to an embodiment of the present invention.
Description of reference numerals:
1. an abdominal aortic stent; 11. an abdominal aortic stent unit; 2. fixing a bracket; 21. a bare area part; 22. a connecting portion; 3. a polyester film; 4. an elastic connecting member; 5. and barbs.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
Example (b):
as shown in fig. 1, a naked-region degradable abdominal aorta stent graft comprises a fixed stent 2 and a plurality of wavy abdominal aorta stent units 11, wherein each abdominal aorta stent unit 11 is wound into a ring shape, the plurality of annular wound abdominal aorta stent units 11 are sequentially arranged to form an abdominal aorta stent 1, the abdominal aorta stent 1 comprises a main stent at the front end thereof and two branch stents at the distal end of the abdominal aorta stent 1, the main stent is in a straight-tube structure, the outer diameter of the main stent is 20mm-30mm, and the outer diameter of the branch stents is 12mm-14 mm; the fixed support 2 is wavy, the fixed support 2 is wound into a ring shape, the fixed support 2 is provided with a naked area part 21 and a connecting part 22 which are integrally formed and respectively positioned at two ends of the fixed support 2 wound into the ring shape, the connecting part 22 is arranged at one end of the abdominal aorta support 1, and the connecting part 22 and the abdominal aorta support 1 are coated with polyester films 3 together; the naked area part 21 of the fixed support 2 is made of magnesium alloy or iron alloy material, and the abdominal aorta support 1 is made of medical stainless steel material or nickel-titanium alloy material.
In the structure, the aorta abdominalis covered stent comprises an aorta abdominalis stent 1 and a fixed stent 2, a plurality of independent aorta abdominalis stent units 11 in the aorta abdominalis stent 1 are fixedly coated with a connecting part 22 of the fixed stent 2 through a polyester film 3 to form the aorta abdominalis covered stent with a main stent and two branch stents, a naked region part 21 of the fixed stent 2 is exposed and used for fixing the aorta abdominalis covered stent, moreover, the naked region of the fixed stent 2 is made of degradable magnesium alloy or iron alloy material, after the aorta abdominalis covered stent is placed in a human body for a period of time, the aorta abdominalis covered stent is fused with the aorta abdominalis (at the moment, the naked region 21 with the fixing function is gradually absorbed by the human body and is degraded, compared with the traditional structure that the naked region is not degradable and adopts a barb, the artery wall scratch caused by the fact that the abdominal aorta covered stent is placed in a human body for a long time is avoided.
In one embodiment, the length of the bare area 21 is 10mm-15mm, so that the contact area between the bare area 21 and the abdominal artery wall can be reduced while ensuring sufficient connection stability, and therefore, the scratch on the abdominal artery wall can be reduced.
In one embodiment, as shown in fig. 2 and 4, the bare area 21 is in the shape of a corolla with a larger outer diameter at the front end than at the rear end, and the arc center angle of the arc-shaped bent portion of the bare area 21 is 18 ° to 23 °.
Furthermore, the front end of the naked area part 21 is provided with an arc part with a bending radian towards the inner side of the abdominal aorta covered stent, the length of the arc part is 3mm-4mm, the arc center angle of the arc part is 50-60 degrees, a smooth boss is formed at the joint of the naked area part 21 and the arc part, the firmness of the stent in the renal aorta can be further improved, the scratch is reduced, meanwhile, the arc center angle of the naked area part 21 is 18-23 degrees, the arc center angle of the arc part is 50-60 degrees, the smoothness of the integral structure of the naked area part 21 and the arc part can be ensured, and meanwhile, the naked area part 21 has enough strength.
In one embodiment, the minimum outer diameter of the connecting part 22 wound in a ring shape is the same as the outer diameter of the abdominal aorta stent unit 11 wound in a ring shape, and the difference between the maximum outer diameter of the bare area part 21 wound in a ring shape and the outer diameter of the abdominal aorta stent unit 11 wound in a ring shape is 2mm to 3mm, so that the protruding height of the boss formed at the front end of the bare area part 21 is 1mm to 1.5mm, and the contact fusion between the abdominal aorta covered stent and the abdominal aorta is not affected.
In one embodiment, the bare area portion 21 is provided with a barb 5 toward the distal end of the abdominal aortic stent 1, so as to prevent the abdominal aortic stent 1 from sliding downward.
In one embodiment, as shown in fig. 3, when the connecting portion 22 and the abdominal aorta stent unit 11 are wound in a ring shape, the end-to-end connection can be completed by the elastic connecting member 4, and the elastic connecting member 4 is in a compressed state, so that the change of the internal diameter of the abdominal aorta of the patient in different age periods can be adapted, and as the patient expands from a young age to an adult age period and the internal diameter of the abdominal aorta is expanded from 2-5mm to 15-20mm, the elastic connecting member 4 stretches under the action of self tension, so that the external diameter of the abdominal aorta covered stent gradually expands and always keeps in fit with the internal diameter of the abdominal aorta, and the abdominal aorta is ensured to be always in a smooth state. Alternatively, the connecting portion 22 and the abdominal aorta stent 1 may also be made of other medical materials with certain elasticity, and the elastic connecting member 4 is connected between the connecting portion 22 and two adjacent nodes of the abdominal aorta stent unit 11, and the elastic connecting member 4 is always in a compressed state, so as to realize the later expansion of the abdominal aorta stent graft.
A preparation method of a naked degradable abdominal aorta covered stent comprises the following steps:
s1, taking medical stainless steel or titanium alloy wire materials, bending the medical stainless steel or titanium alloy wire materials into a zigzag wavy abdominal aorta stent unit, and winding the abdominal aorta stent unit into a ring shape;
s2, sequentially arranging a plurality of annularly wound abdominal aorta stent units to form an abdominal aorta stent with a main stent and two branch stents;
s3, taking medical magnesium alloy or iron alloy material, bending the medical magnesium alloy or iron alloy material in a Z shape to form a wavy fixed support, and winding the fixed support into a ring shape;
s4, bending the naked area of the fixed stent to the outer side of the aorta abdominalis covered stent at an arc center angle of 18-23 degrees;
s5, welding barbs of magnesium alloy or iron alloy materials on the bare area part of the fixing support;
s6, winding the abdominal aorta stent unit and the fixed stent into a ring shape;
and S7, butting the connecting part of the fixed support with the front end of the abdominal aorta support, and coating the connecting part of the abdominal aorta support and the fixed support by adopting a polyester film to obtain the degradable abdominal aorta covered stent in the naked region.
In one embodiment, the length of the bare region of the fixing stent described in step S4 is 10mm to 15 mm.
In one embodiment, the polyester film described in step S8 entirely covers the connection part of the fixing support, and the front end part of the polyester film covers the bare area part of the fixing support.
The above-mentioned embodiments only express the specific embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.
Claims (8)
1. The naked-region degradable abdominal aorta covered stent is characterized by comprising a fixed stent and a plurality of wavy abdominal aorta stent units, wherein each abdominal aorta stent unit is wound into a ring shape, the plurality of annular abdominal aorta stent units wound into the ring shape are sequentially arranged to form the abdominal aorta stent, the abdominal aorta stent comprises a main stent positioned at the front end of the abdominal aorta stent and two branch stents positioned at the far ends of the abdominal aorta stent, the main stent is in a straight-tube structure, the outer diameter of the main stent is 20mm-30mm, and the outer diameter of each branch stent is 12mm-14 mm; the fixed support is wavy and wound into a ring, the fixed support is provided with a naked area part and a connecting part which are integrally formed and respectively positioned at two ends of the fixed support wound into the ring, the connecting part is arranged at one end of the abdominal aorta support, and the connecting part and the abdominal aorta support are coated with polyester films together; the naked area part of fixed bolster is magnesium alloy or ferroalloy material, the aorta abdominalis support is medical stainless steel material or nickel titanium alloy material.
2. The bare area degradable abdominal aorta covered stent according to claim 1, wherein the length of the bare area is 10mm-15 mm.
3. The bare area degradable abdominal aorta covered stent according to claim 2, wherein the bare area is in a corolla shape with a larger outer diameter of the front end than the rear end, and the arc center angle of the arc-shaped bent part of the bare area is 18-23 °.
4. The bare area degradable abdominal aortic stent graft of claim 3, wherein the minimum outer diameter of the connecting portion wound in a ring shape is the same as the outer diameter of the abdominal aortic stent unit wound in a ring shape, and the difference between the maximum outer diameter of the bare area wound in a ring shape and the outer diameter of the abdominal aortic stent unit wound in a ring shape is 2mm-3 mm.
5. The bare area degradable abdominal aortic stent graft of claim 4, wherein the bare area portion is provided with barbs disposed towards the distal end of the abdominal aortic stent.
6. The method for preparing a bare area degradable abdominal aorta covered stent according to any one of claims 1 to 5, comprising the following steps:
s1, taking medical stainless steel or titanium alloy wire materials, bending the medical stainless steel or titanium alloy wire materials into a zigzag wavy abdominal aorta stent unit, and winding the abdominal aorta stent unit into a ring shape;
s2, sequentially arranging a plurality of annularly wound abdominal aorta stent units to form an abdominal aorta stent with a main stent and two branch stents;
s3, taking medical magnesium alloy or iron alloy material, bending the medical magnesium alloy or iron alloy material in a Z shape to form a wavy fixed support, and winding the fixed support into a ring shape;
s4, bending the naked area of the fixed stent to the outer side of the aorta abdominalis covered stent at an arc center angle of 18-23 degrees;
s5, welding barbs of magnesium alloy or iron alloy materials on the bare area part of the fixing support;
s6, winding the abdominal aorta stent unit and the fixed stent into a ring shape;
and S7, butting the connecting part of the fixed support with the front end of the abdominal aorta support, and coating the connecting part of the abdominal aorta support and the fixed support by adopting a polyester film to obtain the degradable abdominal aorta covered stent in the naked region.
7. The method for preparing a bare area degradable abdominal aorta covered stent according to claim 6, wherein the length of the bare area of the fixed stent in the step S4 is 10mm-15 mm.
8. The method of preparing a bare area degradable abdominal aorta covered stent according to claim 6, wherein the polyester film covers all the connection parts of the stent in step S8, and the tip part of the polyester film covers the bare area part of the stent.
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| CN201910955419.5A CN110721008B (en) | 2019-10-09 | 2019-10-09 | Degradable abdominal aorta covered stent in bare area and preparation method thereof |
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| CN201910955419.5A CN110721008B (en) | 2019-10-09 | 2019-10-09 | Degradable abdominal aorta covered stent in bare area and preparation method thereof |
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| CN110721008B CN110721008B (en) | 2024-02-20 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113331992A (en) * | 2021-04-30 | 2021-09-03 | 光华临港工程应用技术研发(上海)有限公司 | Aorta covered stent |
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