CN110693032A - Food containing L-carnitine and haematococcus pluvialis - Google Patents
Food containing L-carnitine and haematococcus pluvialis Download PDFInfo
- Publication number
- CN110693032A CN110693032A CN201910881530.4A CN201910881530A CN110693032A CN 110693032 A CN110693032 A CN 110693032A CN 201910881530 A CN201910881530 A CN 201910881530A CN 110693032 A CN110693032 A CN 110693032A
- Authority
- CN
- China
- Prior art keywords
- carnitine
- sperm
- haematococcus pluvialis
- vitamin
- food containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title claims abstract description 26
- 241000168517 Haematococcus lacustris Species 0.000 title claims abstract description 24
- 235000013305 food Nutrition 0.000 title claims abstract description 13
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 19
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 16
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 16
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 14
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 11
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000011575 calcium Substances 0.000 claims abstract description 11
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 11
- 235000001465 calcium Nutrition 0.000 claims abstract description 11
- 235000011649 selenium Nutrition 0.000 claims abstract description 11
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 11
- 239000011669 selenium Substances 0.000 claims abstract description 11
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 9
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 9
- 239000011709 vitamin E Substances 0.000 claims abstract description 9
- 229940046009 vitamin E Drugs 0.000 claims abstract description 9
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 8
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 8
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims abstract description 8
- 235000013734 beta-carotene Nutrition 0.000 claims abstract description 8
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims abstract description 8
- 239000011648 beta-carotene Substances 0.000 claims abstract description 8
- 229960002747 betacarotene Drugs 0.000 claims abstract description 8
- 229960000304 folic acid Drugs 0.000 claims abstract description 8
- 235000019152 folic acid Nutrition 0.000 claims abstract description 8
- 239000011724 folic acid Substances 0.000 claims abstract description 8
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 8
- 239000011718 vitamin C Substances 0.000 claims abstract description 8
- 235000016804 zinc Nutrition 0.000 claims abstract description 8
- 239000011701 zinc Substances 0.000 claims abstract description 8
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 8
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims abstract description 8
- 229940091258 selenium supplement Drugs 0.000 claims abstract description 6
- 229960001518 levocarnitine Drugs 0.000 claims description 5
- 230000021595 spermatogenesis Effects 0.000 abstract description 4
- 230000000694 effects Effects 0.000 description 10
- 230000019100 sperm motility Effects 0.000 description 10
- 210000000582 semen Anatomy 0.000 description 9
- 208000007466 Male Infertility Diseases 0.000 description 7
- 239000003814 drug Substances 0.000 description 7
- 208000000509 infertility Diseases 0.000 description 6
- 230000036512 infertility Effects 0.000 description 6
- 231100000535 infertility Toxicity 0.000 description 6
- 230000003078 antioxidant effect Effects 0.000 description 5
- 230000004899 motility Effects 0.000 description 5
- 108020004414 DNA Proteins 0.000 description 4
- 239000003963 antioxidant agent Substances 0.000 description 4
- 235000006708 antioxidants Nutrition 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 230000035558 fertility Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 description 3
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 3
- 235000013793 astaxanthin Nutrition 0.000 description 3
- 239000001168 astaxanthin Substances 0.000 description 3
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 description 3
- 229940022405 astaxanthin Drugs 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 150000001746 carotenes Chemical class 0.000 description 3
- 235000005473 carotenes Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 239000006187 pill Substances 0.000 description 3
- 229940068196 placebo Drugs 0.000 description 3
- 239000000902 placebo Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 3
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- 241000252229 Carassius auratus Species 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000004720 fertilization Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000021267 infertility disease Diseases 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000003859 lipid peroxidation Effects 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 230000035800 maturation Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000001550 testis Anatomy 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- 206010003591 Ataxia Diseases 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 206010009260 Cleft lip and palate Diseases 0.000 description 1
- 206010010947 Coordination abnormal Diseases 0.000 description 1
- 230000006820 DNA synthesis Effects 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- 206010048259 Zinc deficiency Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 108091092356 cellular DNA Proteins 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000016653 cleft lip/palate Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000000918 epididymis Anatomy 0.000 description 1
- 201000010063 epididymitis Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000016290 incoordination Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 150000004668 long chain fatty acids Chemical class 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000003228 microsomal effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 201000010193 neural tube defect Diseases 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 230000006825 purine synthesis Effects 0.000 description 1
- 230000006824 pyrimidine synthesis Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 230000008010 sperm capacitation Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 210000004340 zona pellucida Anatomy 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention relates to a food containing L-carnitine and haematococcus pluvialis, which can increase spermatogenesis and comprises L-carnitine, haematococcus pluvialis, beta-carotene, folic acid, zinc, selenium, vitamin C, vitamin E and calcium.
Description
Technical Field
The invention relates to the field of health-care food, in particular to food containing L-carnitine and haematococcus pluvialis.
Background
Male infertility caused by male factors is called male infertility, and male infertility is a disease with high morbidity and difficult cure. The current research data at home and abroad show that: the incidence rate of infertility in couples of childbearing age is about 15% -20%, according to the statistics of the world health organization: there are approximately 600-8000 ten thousand couples worldwide with varying degrees of infertility among which infertility caused by male factors accounts for approximately 50% of all infertile couples.
China has a large population base and a high incidence rate relative to the world level, and the incidence rate of China also tends to rise in recent years. Infertility often causes feelings of couples to be incoordination, marriage family breaks down, and unstable factors are brought to society. Male infertility is characterised by a diverse etiology, the most common and immediate outward manifestation of reduced semen quality. At present, the technical field of Chinese medicine accumulates relatively rich experience in the aspect of treating male infertility, and the Chinese medicine has western medicine treatment, such as medicine, operation, local medicine application and the like, and also has a plurality of effective Chinese patent medicines, such as a kidney tonifying seed prescription, a kidney tonifying and sperm generating pill, a kidney warming pill, a sperm raising pill and the like. And the duration of the drug treatment is long, and many side effects are accompanied, so the operation treatment has large wound. And people prefer to select food supplements preferentially due to the tradition of Chinese nationality. Therefore, the composition and the common food which have obvious effect and no side effect and can improve the semen quality, accelerate the formation of male sperms and improve the fertility have important practical significance.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a health food which has no side effect, is scientific and effective, can improve the semen quality, quickens the formation of male sperms and improves the fertility and contains astaxanthin and trehalose, and the specific technical scheme is as follows:
a food containing L-carnitine and haematococcus pluvialis comprises L-carnitine and haematococcus pluvialis, wherein the mass ratio of the L-carnitine to the haematococcus pluvialis is (200-3400) to (100-1800).
In order to better implement the invention, the method further comprises the following steps:
also comprises one or more of beta-carotene, folic acid, zinc, selenium, vitamin C, vitamin E or calcium.
The components are specifically calculated by weight;
the invention has the beneficial effects that:
l-carnitine: is an essential component for maintaining normal physiological activities of human bodies. It has very important and diverse roles. L-carnitine is an important carrier for transporting energy-supplying substances in human body, on one hand, epididymis and sperms contain a large amount of L-carnitine, long-chain fatty acids can be transported into sperms and granules of the sperms to perform beta oxidation, mitochondria are provided for movement of the sperms, and on the other hand, wastes such as acetyl, lactic acid and the like generated by metabolism can be transported out of the sperms to maintain normal functions of the sperms [9 ]. In addition, the substance has strong reducibility, and can reduce the level of oxidative stress in sperm and protect sperm structure [10 ]. The addition of this substance to the culture medium has been shown in the literature to increase sperm motility, sperm density and sperm DNA integrity.
Haematococcus pluvialis: astaxanthin, which is the main content of haematococcus pluvialis, is the strongest antioxidant found in the nature by people so far, the antioxidant activity of the haematococcus pluvialis is far higher than that of the existing antioxidant, and the haematococcus pluvialis can effectively eliminate oxygen free radicals in cells, enhance the cell regeneration capacity, maintain the organism balance, reduce the accumulation of aged cells and protect the cell and DNA health from inside to outside. Astaxanthin can improve the motility of human sperms, increase the capacity of sperms to pass through the zona pellucida, and increase the success rate of conception of infertility patients in an artificial fertilization cycle. Haematococcus pluvialis maintains the normal morphology and DNA integrity of the sperm.
Beta-carotene: beta-carotene is an antioxidant, and can maintain the integrity of the microsomal membranes, prevent the generation of oxygen free radicals, stimulate the metabolism of the skin, and promote blood circulation.
Folic acid: folic acid is a water-soluble vitamin, plays an important role in protein synthesis and metabolism of various amino acids, participates in purine and pyrimidine synthesis, and plays a role in cellular DNA synthesis. It can prevent low fetal weight, cleft lip and palate, cardiac defect, and neural tube developmental defect.
Zinc: this material is abundantly present in the male testes and is involved in the overall process of spermatogenesis, maturation and capacitation. Once men lack zinc, the number of sperms is reduced, the vitality is reduced, the semen is poorly liquefied, and the men are infertile. The zinc deficiency can also lead to the fact that teenagers have no secondary sexual characteristics and can not normally reproduce and develop.
Selenium: the substance is an essential component of peroxidase in seminal plasma, the selenium level in the seminal fluid of male infertility patients is generally low, and researches show that: the higher the selenium level in the semen, the greater the number of sperm and the greater the motility. Selenium has strong antioxidation effect, can scavenge excessive free radicals, and inhibit lipid peroxidation. The low level of the selenium in the semen of the male infertility patient naturally weakens the elimination of oxygen free radicals and the inhibition of lipid peroxidation in the semen by the organism, thereby causing the low sperm motility, high mortality rate and the infertility of the patient.
Vitamin C: in human body, vitamin C is a highly effective antioxidant, and is also required to participate in many important biosynthesis processes, and can improve sperm quality.
Vitamin E: vitamin E can maintain reproductive function. Vitamin E hydrolysis can produce tocopherol, which increases the motility and number of male sperm, and improves the quality and motility of male sperm.
Calcium: calcium is an important mineral affecting sperm motility, and a deficiency in calcium can lead to a decrease in sperm motility.
The L-carnitine and the composition provided by the invention can increase spermatogenesis, promote sperm proliferation and maturation, supply energy to sperms, increase sperm motility, protect the integrity of sperm cell membranes, increase sperm DNA stability and comprehensively improve sperm quality, so that a satisfactory effect can be achieved.
Has the following advantages: 1. the curative effect is better, can promote the function improvement of spermatids of spermaduct mesenchyme of testicle after taking, enhance the sexual function, promote the spermatogenesis, improve the sperm activity, improve the fertility effectively; 2. has wide application range, is suitable for people of various ages, particularly has good curative effect on the reduction of fertility caused by the increase of age, and has no obvious side effect.
Drawings
FIG. 1 shows the change of sperm index after goldfish of the present invention eat 50, 100, 150mg carotene-containing diet;
FIG. 2 is a table showing the variation of sperm concentration, pronated sperm, linear motor index, etc. of L-carnitine and placebo treatment over a treatment cycle in accordance with the present invention;
FIG. 3 is a graph showing the effect of extracellular calcium concentration on sperm motility in the present invention.
Detailed Description
The following detailed description of the preferred embodiments of the present invention, taken in conjunction with the accompanying drawings, will make the advantages and features of the invention easier to understand by those skilled in the art, and thus will clearly and clearly define the scope of the invention.
The first embodiment is as follows:
a food containing L-carnitine and Haematococcus pluvialis comprises L-carnitine, Haematococcus pluvialis, beta-carotene, folic acid, zinc, selenium, vitamin C, vitamin E, and calcium. Preparing powder according to the weight components;
the preparation is administered 1 bag a day, and 30 days as a treatment course for 3 treatment courses.
Example two:
a food containing L-carnitine and Haematococcus pluvialis comprises L-carnitine, Haematococcus pluvialis, beta-carotene, folic acid, zinc, selenium, vitamin C, vitamin E, and calcium. Preparing powder according to the weight components;
the preparation is administered 1 bag a day, and 30 days as a treatment course for 2 treatment courses.
Example three:
a food containing L-carnitine and Haematococcus pluvialis comprises L-carnitine, Haematococcus pluvialis, beta-carotene, folic acid, zinc, selenium, vitamin C, vitamin E, and calcium. Preparing powder according to the weight components;
the preparation is administered 1 bag a day, and 30 days as a treatment course for 4 treatment courses.
And (3) experimental verification: as shown in fig. 1: after goldfish eat diet containing 50, 100, 150mg carotene, sperm index changes. The osmotic pressure, sperm motility, fertilization rate and sperm concentration of 150 mg/kg carotene were significantly higher than those of the control group.
As shown in fig. 2: variation of sperm concentration, forward sperm, linear motility index, etc. parameters after l-carnitine and placebo treatment over the treatment period. The changes in total sperm motility, forward sperm, sperm concentration and linear movement index were all more significant after l-carnitine treatment than after placebo treatment.
As shown in fig. 3: effect of extracellular calcium concentration on sperm motility. An extracellular calcium ion concentration of 10 μ M is the optimal concentration to obtain optimal sperm motility.
Claims (3)
1. A food containing L-carnitine and Haematococcus pluvialis is characterized in that: comprises L-carnitine and haematococcus pluvialis, wherein the mass ratio of the L-carnitine to the haematococcus pluvialis is (200-3400): 100-1800).
2. The food product of claim 1, comprising l-carnitine and haematococcus pluvialis, wherein: also comprises one or more of beta-carotene, folic acid, zinc, selenium, vitamin C, vitamin E or calcium.
3. The food product of claim 2, comprising l-carnitine and haematococcus pluvialis, wherein: the components are specifically calculated by weight;
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910881530.4A CN110693032A (en) | 2019-09-18 | 2019-09-18 | Food containing L-carnitine and haematococcus pluvialis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910881530.4A CN110693032A (en) | 2019-09-18 | 2019-09-18 | Food containing L-carnitine and haematococcus pluvialis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110693032A true CN110693032A (en) | 2020-01-17 |
Family
ID=69194858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910881530.4A Pending CN110693032A (en) | 2019-09-18 | 2019-09-18 | Food containing L-carnitine and haematococcus pluvialis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110693032A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668507A (en) * | 2016-12-29 | 2017-05-17 | 昭远制药(上海)有限公司 | Medicine for curing male infertility and preparation method thereof |
| CN107157969A (en) * | 2017-06-15 | 2017-09-15 | 中盐工程技术研究院有限公司 | A kind of natural Astaxanthin In Haematococcus Pluvialis soft capsule |
| CN107536055A (en) * | 2017-10-19 | 2018-01-05 | 杭州鑫伟低碳技术研发有限公司 | A kind of infertile Astaxanthin In Haematococcus Pluvialis product formula of auxiliary treatment |
| CN107889889A (en) * | 2017-10-26 | 2018-04-10 | 杭州鑫伟低碳技术研发有限公司 | A kind of formula for the Astaxanthin In Haematococcus Pluvialis milk powder for contributing to recovery of parturient |
| CN108041588A (en) * | 2017-12-08 | 2018-05-18 | 冯纪敏 | A kind of composition containing trehalose and its application |
-
2019
- 2019-09-18 CN CN201910881530.4A patent/CN110693032A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668507A (en) * | 2016-12-29 | 2017-05-17 | 昭远制药(上海)有限公司 | Medicine for curing male infertility and preparation method thereof |
| CN107157969A (en) * | 2017-06-15 | 2017-09-15 | 中盐工程技术研究院有限公司 | A kind of natural Astaxanthin In Haematococcus Pluvialis soft capsule |
| CN107536055A (en) * | 2017-10-19 | 2018-01-05 | 杭州鑫伟低碳技术研发有限公司 | A kind of infertile Astaxanthin In Haematococcus Pluvialis product formula of auxiliary treatment |
| CN107889889A (en) * | 2017-10-26 | 2018-04-10 | 杭州鑫伟低碳技术研发有限公司 | A kind of formula for the Astaxanthin In Haematococcus Pluvialis milk powder for contributing to recovery of parturient |
| CN108041588A (en) * | 2017-12-08 | 2018-05-18 | 冯纪敏 | A kind of composition containing trehalose and its application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Carroll et al. | Influence of stress and nutrition on cattle immunity | |
| FR2860976A1 (en) | Use of oral synergistic composition for treating e.g. cerebral or cardiac dysfunction, contains omega-3 fatty acids, at least two vitamins and at least two trace elements | |
| Bai et al. | Glutamine improves the growth performance, serum biochemical profile and antioxidant status in broilers under medium-term chronic heat stress | |
| CN105768108A (en) | Special dietary food suitable for taking of tumor patients | |
| CN102846673A (en) | Composition for improving human sperm motility and quality | |
| EP2481300B1 (en) | Nutritional composition for equine reproductive health | |
| Aramli et al. | Effect of dietary antioxidant supplements (selenium forms, alpha-tocopherol, and coenzyme Q10) on growth performance, immunity, and physiological responses in rainbow trout (Oncorhynchus mykiss) using orthogonal array design | |
| CN110584116A (en) | A food containing Haematococcus pluvialis and trehalose | |
| CN102793184A (en) | Compound antioxidant nutrition supplement and processing method thereof | |
| RU2018129357A (en) | APPLICATION OF A SIMULAR DIET-DIED NUTRITION TO IMPROVE ANTIESTROGEN EFFICIENCY IN CANCER THERAPY | |
| US20160367500A1 (en) | Compositions comprising vitamin c, vitamin e, and coenzyme q10 and use thereof for promoting female fertility and reproductive health | |
| CN110693032A (en) | Food containing L-carnitine and haematococcus pluvialis | |
| CN104222624A (en) | Vitamin premix for milk cow and preparation method of vitamin premix | |
| CN101401649A (en) | Composition capable of reinforcing organism phylactic power | |
| CN108041588A (en) | A kind of composition containing trehalose and its application | |
| CN110613124A (en) | Health food containing L-carnitine and astaxanthin | |
| CA2134707A1 (en) | Methods and compositions for retarding the aging process | |
| CN110558563A (en) | A health composition containing semen Castaneae polysaccharide and L-carnitine | |
| CN104983903A (en) | Composite rhodiola rosea preparation for improving anoxia endurance | |
| CN108371709A (en) | Lycium ruthenicum tumor recovering gene enzyme | |
| Bendich | Issues in retinoid and carotenoid research | |
| Sonawane et al. | A Review Article on ‘Spirulina’ | |
| Falahat Naserabad et al. | Effects of selenium nanoparticles on the performance of antioxidant enzymes and ions of rainbow trout eggs (Oncorhynchus mykiss) | |
| Lv et al. | Effects of dietary supplementation of nano-selenium on the egg selenium content and egg production rate of North China hens | |
| RU2317073C1 (en) | Method for preventing puerperal diseases in cows |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200117 |