CN110686439A - Automatic refrigeration constant-temperature ice bag and preparation process thereof - Google Patents
Automatic refrigeration constant-temperature ice bag and preparation process thereof Download PDFInfo
- Publication number
- CN110686439A CN110686439A CN201910911897.6A CN201910911897A CN110686439A CN 110686439 A CN110686439 A CN 110686439A CN 201910911897 A CN201910911897 A CN 201910911897A CN 110686439 A CN110686439 A CN 110686439A
- Authority
- CN
- China
- Prior art keywords
- bag
- temperature
- ice
- refrigerant
- inner bag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D5/00—Devices using endothermic chemical reactions, e.g. using frigorific mixtures
- F25D5/02—Devices using endothermic chemical reactions, e.g. using frigorific mixtures portable, i.e. adapted to be carried personally
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Packages (AREA)
Abstract
The invention discloses an automatic refrigeration constant-temperature ice bag and a preparation process thereof. The automatic refrigeration constant temperature ice bag comprises an outer bag, wherein an inner bag, a refrigerant and a coolant are arranged in the outer bag, and the inner bag is hermetically filled with water. According to the automatic refrigeration constant-temperature ice bag, the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant temperature ice bag has small volume, light weight, portability, convenient use and random access, and can be provided with different numbers of ice bags according to the number and the volume of medical biological products. The preparation process of the automatic refrigeration constant temperature ice bag comprises the following steps: filling water into the inner bag, and sealing; the inner bag, the refrigerant and the cold storage agent are filled in the outer bag and sealed.
Description
Technical Field
The invention relates to the technical field of medical biological product cold chain transportation, in particular to an automatic refrigeration constant-temperature ice bag and a preparation process thereof.
Background
The medical cold chain transportation needs to be carried by a refrigerator car, and the temperature is controlled to be 2-At the temperature of 8 ℃, and can not be transported together with fruits and seafood. The company like the Shufeng cold chain charges 250 Yuan for short-distance transportation within 100 kilometers, and the transportation cost is high.
Some companies with strong strength and large sales quantity configure refrigerated vehicles by themselves and transport medical cold chain goods by themselves. The companies with weak strength and low sales volume cannot arrange the refrigerator cars by themselves or carry the goods such as the smooth and rich cold chain.
The short-distance transportation can adopt foamThe heat preservation box is matched with a proper amount of ice bags, so that the temperature can be kept at 2 DEG-Transporting the medical biological product at 8 ℃. The traditional ice bag needs to be frozen in a refrigerator for 24 hours and can be used after cold accumulation. The refrigerator is depended on, the power supply is depended on, the time is limited, and the refrigerator cannot be taken and used at any time. For some outdoor and special cases, the refrigerator is not available, the power supply is not available, and the refrigerator is required to be used immediately, which is very inconvenient.
Some companies adopt a normal-temperature transportation mode for vaccines due to various condition limitations of medical cold-chain long-distance transportation and short-distance transportation, so that a toxic vaccine event with great social harm is caused. The vaccine stimulates the human immune system through the antigen part, thereby protecting the human health. The core of the vaccine is antigen, the biological activity of the antigen is not ensured, and most of the vaccines are 2-Storing and transporting at 8 deg.C. The problems caused by vaccine inactivation are two kinds: 1. vaccine inactivation is not perceived and can have serious consequences for vaccines such as rabies, tetanus and the like, by exposing the vaccinee unconsciously to the corresponding disease. 2. Inactivation of the vaccine, which corresponds to injection of the corresponding pathogen into the vaccinee, leads to the development of new diseases.
Disclosure of Invention
Based on the above, the invention aims to provide an automatic refrigeration constant-temperature ice bag and a preparation process thereof.
The automatic refrigeration constant temperature ice bag comprises an outer bag, wherein an inner bag, a refrigerant and a coolant are arranged in the outer bag, and the inner bag is hermetically filled with water.
According to the automatic refrigeration constant-temperature ice bag, the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant temperature ice bag has small volume, light weight, portability, convenient use and random access, and can be provided with different numbers of ice bags according to the number and the volume of medical biological products.
Further preferably, the refrigerant is carbamide. The carbamide can absorb heat and refrigerate quickly when dissolved in water, so that the temperature is quickly reduced to about 2 ℃, and the carbamide has low price and high safety, and can reduce the production cost and ensure the safety.
Further preferably, the coolant is sodium polyacrylate. The sodium polyacrylate is a high molecular compound with hydrophilic and hydrophobic groups, is slowly dissolved in water to form extremely viscous transparent gel, so that the constant temperature is kept for a long time, the temperature is conveniently controlled to be 2-8 ℃, the cost of the sodium polyacrylate is low, the sodium polyacrylate is safe, and the manufactured ice bag is cheap, high in quality and safe.
Further preferably, the refrigerant, the water, and the coolant are 105 parts, 100 parts, and 5 parts, respectively, by mass. The refrigerant, the water and the coolant are arranged according to the mass parts, so that the refrigeration and constant temperature effects of the ice bag can be ensured while materials are saved and the volume is reduced.
Further preferably, the outer bag is a closed composite film bag. The composite film bag has stable structure and low cost.
Further preferably, the inner bag is a sealed plastic bag. The plastic bag is convenient to break by pinching and has low cost.
Further preferably, a non-woven fabric bag is arranged in the outer bag, and the coolant is filled in the non-woven fabric bag. The non-woven fabric bag can facilitate the solution to permeate, so that the coolant is more fully dissolved in the solution.
Further preferably, the outer bag has a specification of 25 cmX12.5cm;
the specification of the inner bag is 12cmX8 cm;
the specification of the non-woven cloth bag is 8cmX6 cm.
The outer bag, the inner bag and the non-woven bag are designed into the specifications, so that the ice bag has small volume, light weight, portability, convenient use and low production cost.
Compared with the prior art, the automatic refrigeration constant-temperature ice bag has the advantages that the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant-temperature ice bag has small volume, light weight, portability, convenient use and convenient taking at any time, and can be provided with ice bags with different quantities according to the quantity and the volume of reagents. The automatic refrigeration constant temperature ice bag has the characteristics of simple structure, small volume, convenient use and the like.
The invention further provides a preparation process of the automatic refrigeration constant-temperature ice bag, which comprises the following steps:
filling water into the inner bag, and sealing;
the inner bag, the refrigerant and the cold storage agent are filled in the outer bag and sealed.
The preparation process of the automatic refrigeration constant-temperature ice bag is simple in preparation process, low in preparation cost and suitable for popularization and application.
For a better understanding and practice, the invention is described in detail below with reference to the accompanying drawings.
Drawings
Fig. 1 is a schematic structural view of a preferred structure of the automatic refrigerating constant temperature ice bag of the present invention.
Detailed Description
The terms of orientation of up, down, left, right, front, back, top, bottom, and the like, referred to or as may be referred to in this specification, are defined relative to the configuration shown in the figures, and are relative concepts. Therefore, it may be changed according to different positions and different use states. Therefore, these and other directional terms should not be construed as limiting terms.
The implementations described in the exemplary embodiments below are not intended to represent all implementations consistent with the present disclosure. Rather, they are merely examples of methods consistent with certain aspects of the present disclosure, as detailed in the appended claims.
The terminology used in the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in this disclosure and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
Referring to fig. 1, fig. 1 is a schematic structural view of a preferred structure of an automatic refrigerating and constant temperature ice bag according to the present invention.
The automatic refrigeration constant temperature ice bag comprises an outer bag 1, wherein an inner bag 2, a refrigerant 3 and a coolant are arranged in the outer bag 1, and the inner bag 2 is hermetically filled with water. The inner bag 2, the refrigerant 3 and the coolant are arranged in the outer bag 1, after the inner bag 2 is pinched to be broken, the water in the inner bag 2 flows out to fully contact with the refrigerant 3, so that the temperature can be quickly reduced, and after the temperature is reduced, the coolant is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag 1 is kept in a low-temperature state for a long time; the automatic refrigeration constant temperature ice bag has small volume, light weight, portability, convenient use and random access, and can be provided with different numbers of ice bags according to the number and the volume of medical biological products.
Specifically, the outer bag 1 is a sealed composite film bag. The composite film bag has stable structure and low cost.
The inner bag 2 is a sealed plastic bag. The plastic bag is convenient to break by pinching and has low cost.
Preferably, a non-woven fabric bag 4 is arranged in the outer bag 1, and the coolant is filled in the non-woven fabric bag 4. The non-woven fabric bag 4 can facilitate the infiltration of the solution, so that the coolant is more fully dissolved in the solution.
The outer bag 1 of this example had a size of 25 cmX12.5cm.
The specification of the inner bag 2 is 12cmX8 cm.
The specification of the non-woven cloth bag 4 is 8cmX6 cm.
The outer bag 1, the inner bag 2 and the non-woven bag 4 are designed into the specifications, so that the ice bag has small volume, light weight, portability, convenient use and low production cost.
The refrigerant 3 of the present embodiment is preferably selected from carbamide. The carbamide can absorb heat and refrigerate quickly when dissolved in water, so that the temperature is quickly reduced to about 2 ℃, and the carbamide has low price and high safety, and can reduce the production cost and ensure the safety.
The cold-storage agent is preferably sodium polyacrylate. The sodium polyacrylate is a high molecular compound with hydrophilic and hydrophobic groups, is slowly dissolved in water to form extremely viscous transparent gel, so that the constant temperature is kept for a long time, the temperature is conveniently controlled to be 2-8 ℃, the cost of the sodium polyacrylate is low, the sodium polyacrylate is safe, and the manufactured ice bag is cheap, high in quality and safe.
The refrigerant 3, the water and the coolant are 105 parts, 100 parts and 5 parts by mass respectively. The refrigerant 3, the water and the coolant are arranged according to the mass parts, so that the refrigeration and constant temperature effects of the ice bag can be ensured while materials are saved and the volume is reduced.
The refrigerant 3, water, and coolant of the present embodiment are respectively set to 105g, 100g, and 5 g.
The invention discloses a using method of an automatic refrigeration constant-temperature ice bag, which comprises the following steps:
the inner bag 2 is broken by pinching, water in the inner bag 2 flows out and is fully contacted with the solid of the refrigerant 3, and the temperature is rapidly reduced to 2 ℃. Shaking the ice bag to make the coolant in the non-woven bag 4 contact with the solution to form gel, storing the gel in the ice bag to reach the biological reagent refrigeration temperature 2-And (4) putting the cold storage boxes at the temperature of 8 ℃, and configuring different quantities according to the goods and the volume of the cold storage boxes. After once use, the ice bag can be used as a constant temperature ice bag and put into a refrigerator for cold storage and repeated use.
The coolant of the automatic refrigeration constant temperature ice bag of the invention ensures that the constant temperature is kept for a long time, and is convenient for temperature control and transportation. The automatic refrigeration constant-temperature ice bag has the cost of about 2 yuan/bag, is cheap and good, and has the transportation cost of about 1/10 of the cost of a cold chain, which is the cost of common express delivery.
Note that:
1. if the outer package is damaged and the content overflows, the package can not be used.
2. If the product is accidentally damaged and the contents are stained on the skin or eyes, the product can be cleaned with clear water.
3. Storage conditions are as follows: storing in a cool and dry place.
In order to prove the effect of the automatic refrigerating constant-temperature ice bag, the following experiments were carried out using the commercially available ice bag and the components in the automatic refrigerating constant-temperature ice bag of the present invention:
and (3) analyzing an experimental result: experiments carried out by using the components in the automatic refrigeration constant-temperature ice bag can rapidly reduce the temperature to below 2 ℃ within 90 seconds, the temperature reduction time and temperature are obviously better than those of common ice bags or similar mixtures purchased in the market, the raw materials are safe, and the method is not limited by the national purchase policy.
The automatic refrigeration constant temperature ice bag of the invention is compared with the similar ice bag of another applied patent, and the list is as follows:
compared with the prior art, the automatic refrigeration constant-temperature ice bag has the advantages that the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant-temperature ice bag has small volume, light weight, portability, convenient use and convenient taking at any time, and can be provided with ice bags with different quantities according to the quantity and the volume of reagents. The automatic refrigeration constant temperature ice bag has the characteristics of simple structure, small volume, convenient use and the like.
The automatic refrigeration constant temperature ice bag has the beneficial effects that:
1. the patient benefits.
Due to the high cost of cold chain transportation of biological products, such cost is transferred to patients, which increases the economic burden and mental burden of patients. Some companies are on the other hand not 2 due to the high cost of cold chain transportation-The transportation of medical biologicals between 8 ℃ like "vaccine" events seriously jeopardizes the health of the patient. The automatic refrigeration constant-temperature ice bag can help some patients to transport medical biological products in a cold chain, such as insulin in the cold chain of diabetic patients.
2. The hospital benefits.
Due to the high cost of cold chain transportation of biological products, such costs are also transferred to hospitals, which increases the cost and the medical insurance payment burden of hospitals. If the cold chain transportation temperature of the medical biological product is unqualified, medical accidents can be caused, and the reputation of a hospital is influenced. In addition, the medical biological products are frequently transported between the pharmacy and the department in the hospital by cold chain transportation of serum, biological medicines and the like.
3. The manufacturing enterprise benefits.
The automatic refrigeration constant-temperature ice bag is low in price and convenient to use, and reduces the cold chain transportation cost of production enterprises.
The preparation process of the automatic refrigeration constant temperature ice bag comprises the following steps:
water is filled in the inner bag 2 and is sealed;
the inner bag 2, the refrigerant 3 and the cold storage agent are arranged in the outer bag 1 and sealed.
Specifically, 100 ml of water is filled in a plastic bag, and the plastic bag is sealed to form the inner bag 2.5 g of coolant (sodium polyacrylate) is filled in the non-woven cloth bag 4 and sealed. 105g of refrigerant 3 (carbamide) is filled in the composite film bag, and then the inner bag 2 and the non-woven bag 4 are put in and sealed to form the outer bag 1.
The preparation process of the automatic refrigeration constant-temperature ice bag is simple in preparation process, low in preparation cost and suitable for popularization and application.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.
Claims (9)
1. An automatic refrigeration constant temperature ice bag which characterized in that: the cold storage bag comprises an outer bag, wherein an inner bag, a refrigerant and a cold storage agent are arranged in the outer bag, and water is hermetically filled in the inner bag.
2. An automatic refrigerating thermostatic ice bag as claimed in claim 1, wherein: the refrigerant is carbamide.
3. An automatic refrigerating thermostatic ice bag as claimed in claim 2, wherein: the cold storage agent is sodium polyacrylate.
4. An automatic refrigerating thermostatic ice bag as claimed in claim 3, wherein: the refrigerant, the water and the coolant are respectively 105 parts, 100 parts and 5 parts by mass.
5. An automatic refrigerating thermostatic ice bag as claimed in claim 1, wherein: the outer bag is a closed composite film bag.
6. An automatic refrigerating thermostatic ice bag as claimed in claim 1, wherein: the inner bag is a sealed plastic bag.
7. An automatic refrigerating thermostatic ice bag as claimed in any one of claims 1 to 6 wherein: a non-woven fabric bag is arranged in the outer bag, and the coolant is filled in the non-woven fabric bag.
8. An automatic refrigerating thermostatic ice bag as claimed in claim 7 wherein: the specification of the outer bag is 25 cmX12.5cm;
the specification of the inner bag is 12cmX8 cm;
the specification of the non-woven cloth bag is 8cmX6 cm.
9. A preparation process of an automatic refrigeration constant-temperature ice bag is characterized by comprising the following steps:
filling water into the inner bag, and sealing;
the inner bag, the refrigerant and the cold storage agent are filled in the outer bag and sealed.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910911897.6A CN110686439A (en) | 2019-09-25 | 2019-09-25 | Automatic refrigeration constant-temperature ice bag and preparation process thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910911897.6A CN110686439A (en) | 2019-09-25 | 2019-09-25 | Automatic refrigeration constant-temperature ice bag and preparation process thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN110686439A true CN110686439A (en) | 2020-01-14 |
Family
ID=69110164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910911897.6A Pending CN110686439A (en) | 2019-09-25 | 2019-09-25 | Automatic refrigeration constant-temperature ice bag and preparation process thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN110686439A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115368877A (en) * | 2022-09-15 | 2022-11-22 | 浙江大学 | Cold compress material and cold compress assembly based on same |
CN115418198A (en) * | 2022-09-15 | 2022-12-02 | 浙江大学 | Constant-temperature cold compress material, cold compress assembly and cold compress ice bag |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4081256A (en) * | 1976-12-03 | 1978-03-28 | Readi Temp, Inc. | Endothermic composition and cold pack |
CN2054157U (en) * | 1989-07-24 | 1990-03-07 | 邹志刚 | Instantaneously refrigerating ice-bag |
CN202254357U (en) * | 2011-08-11 | 2012-05-30 | 杭州宏畔纸塑包装有限公司 | Brine hot cold pack |
EP2468222A1 (en) * | 2010-12-22 | 2012-06-27 | MIC Medical S.r.l | Device for the application of cold |
CN103608269A (en) * | 2011-04-15 | 2014-02-26 | 克劳泽恩株式会社 | Pouch and method for manufacturing same |
JP2019076325A (en) * | 2017-10-23 | 2019-05-23 | 三菱製紙株式会社 | Cooling pack |
-
2019
- 2019-09-25 CN CN201910911897.6A patent/CN110686439A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4081256A (en) * | 1976-12-03 | 1978-03-28 | Readi Temp, Inc. | Endothermic composition and cold pack |
CN2054157U (en) * | 1989-07-24 | 1990-03-07 | 邹志刚 | Instantaneously refrigerating ice-bag |
EP2468222A1 (en) * | 2010-12-22 | 2012-06-27 | MIC Medical S.r.l | Device for the application of cold |
CN103608269A (en) * | 2011-04-15 | 2014-02-26 | 克劳泽恩株式会社 | Pouch and method for manufacturing same |
CN202254357U (en) * | 2011-08-11 | 2012-05-30 | 杭州宏畔纸塑包装有限公司 | Brine hot cold pack |
JP2019076325A (en) * | 2017-10-23 | 2019-05-23 | 三菱製紙株式会社 | Cooling pack |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115368877A (en) * | 2022-09-15 | 2022-11-22 | 浙江大学 | Cold compress material and cold compress assembly based on same |
CN115418198A (en) * | 2022-09-15 | 2022-12-02 | 浙江大学 | Constant-temperature cold compress material, cold compress assembly and cold compress ice bag |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN110686439A (en) | Automatic refrigeration constant-temperature ice bag and preparation process thereof | |
Lelkens et al. | Experiences with frozen blood products in the Netherlands military | |
WO2007033051A2 (en) | Thermally insulated transport container for cell-based products and related methods | |
US7597196B2 (en) | Insulated medication carrying case | |
US20150069072A1 (en) | Portable Cold Storage Pack for a Blood Bag | |
CN107427837A (en) | Self-heating apparatus for the heating of biological sample | |
CN105716346A (en) | Refrigerant containing bag, refrigerant and refrigerating device | |
Thomas | Platelets: handle with care | |
CN113637460A (en) | Accurate temperature control phase-change material for short-distance transportation of medicines and folding cold storage bag using same | |
Khuu et al. | Catastrophic failures of freezing bags for cellular therapy products: description, cause, and consequences | |
CN106928903A (en) | Compound ultralow temperature phase change cold accumulating agent, its purposes and the cold-storage device containing the agent for storage of coldness | |
KR20190002897U (en) | Immiscible magic ice ball | |
TW200804743A (en) | Portable system for preserving labile materials | |
WO2020078025A1 (en) | Cell preparation for clinical injection, and preparation method therefor and application thereof | |
CN103818651B (en) | A kind of portable medicinal deep freezer | |
CN202144348U (en) | Biological ice box | |
US11612543B2 (en) | Temperature control case for medicament | |
KR101637003B1 (en) | Portable storage container for refrigerated medicine | |
US20170061725A1 (en) | Frozen Freezer Pack | |
Wal et al. | Current practices in insulin and vaccine storage | |
Shinar et al. | The implementation of rapid cooling and overnight hold of whole blood at ambient temperature before processing into components in Israel | |
RU2585464C1 (en) | Sensor for defrosting ofr products based on orange carotenoid protein | |
CN204161836U (en) | A kind of portable medicinal deep freezer | |
CN208775303U (en) | A kind of medicine basket | |
CN205391301U (en) | Medical care car with mixed subassembly of medicine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200114 |