CN110664663A

CN110664663A - Natural efficient anti-hair loss hair restorer

Info

Publication number: CN110664663A
Application number: CN201910965753.9A
Authority: CN
Inventors: 谢爽; J·S·哈里斯; 贾蕾青; 季萍; 张景海
Original assignee: Hangzhou Aibeida Technology Co Ltd
Current assignee: Hangzhou Aibeida Technology Co Ltd
Priority date: 2019-10-12
Filing date: 2019-10-12
Publication date: 2020-01-10

Abstract

The invention provides a natural efficient anti-hair loss pilatory, which comprises the following components in parts by weight: cannabidiol crude oil, argan oil, frankincense oil, tea tree oil, castor oil, bergamot oil and hemp seed oil are weighed according to a formula, the raw materials are put into a mixing kettle and stirred for 10-15 minutes at the temperature of 35-39 ℃ to be homogenized, and the raw materials are kept stand for 2 hours to obtain the natural efficient anti-hair loss pilatory, and the natural efficient anti-hair loss pilatory is bottled by using a rubber head dropper tool. The invention prepares the natural high-efficiency anti-hair loss hair restorer by adopting the cannabidiol crude oil as the main raw material, which is beneficial to inhibiting the activity of 5-alpha reductase by the cannabidiol acting on receptors such as CB1 receptor, TRPV1 receptor, 5-HT1A receptor and the like in human body, thereby controlling the 5 alpha reductase to generate an androgen after the reaction with testosterone in the human body, and achieving the purpose of treating hair loss by reducing the androgen level.

Description

Natural efficient anti-hair loss hair restorer

Technical Field

The invention relates to the technical field of daily chemical compound compositions, in particular to a natural efficient anti-hair loss hair restorer.

Background

The normal amount of hair is removed, which is physiological hair loss. The pathologic alopecia refers to abnormal or excessive hair loss including cicatricial alopecia, androgenetic alopecia, inflammatory alopecia and mechanical injury alopecia. Androgenetic alopecia is the most common alopecia category, about 9 hairs accounting for all the alopecia refer to the phenomenon of hair loss, normal adults drop 70-100 hairs every day, the fallen hairs are in the catagen and the telogen, and the hairs entering the telogen and the newly-grown hairs are in dynamic balance, so 0% can be maintained, the male and the female can develop the disease, and data show that 35 billion dollars are spent on treating the alopecia every year in the world, which is higher than the annual budget of the whole country in Machinton and is also higher than the medical budget of the world in treating malaria. Currently, only 2 varieties of products approved by the FDA to treat alopecia are finasteride and minoxidil, finasteride is the only oral drug approved by the FDA to treat male alopecia and mainly acts on male alopecia, and Nuodier is an external application drug and is a common drug for treating alopecia. The two medicines are required to be taken and used for a long time, and have side effects on human bodies. At present, most of hair restorers and hair shampoo on the market can be mixed with western medicines minoxidil and finasteride, and the hair restorers and the hair shampoo are harmful to human bodies after being used for a long time.

For alopecia, at present, two treatment methods are mainly used in medicine, one is drug treatment, the other is surgery treatment, the drug treatment mainly achieves the treatment effect by taking western medicines of finasteride or minoxidil for a long time, the medicine taking period is long, the effect is slow, and once the medicine is stopped, alopecia is even possibly aggravated, and irreversible damage is caused to the body. The other important is that the operation treatment is performed, the cost is high, hair follicle skin at other parts of the body needs to be taken for transplantation, the transplantation survival rate is not high, the problem of alopecia cannot be solved from the root cause of diseases, and the skin at other parts can cause permanent damage and has certain risk.

Therefore, it is necessary to invent a natural and highly effective hair loss preventive hair restorer to solve the above problems

Disclosure of Invention

The invention aims to provide a natural high-efficiency anti-hair loss hair restorer to solve the technical problems.

In order to solve the technical problems, the invention adopts the following technical scheme:

a natural high-efficiency anti-hair loss pilatory comprises the following components in parts by weight: 2.5g to 7.5g of cannabidiol crude oil, 1.55g to 4.65g of argan oil, 2.7g to 8.1g of frankincense oil, 1.55g to 4.65g of tea tree oil, 1.3g to 3.9g of castor oil, 2.7g to 8.1g of bergamot oil and 150ml to 450ml of hemp seed oil, and the preparation method comprises the following steps:

s1, weighing the raw materials according to the formula, putting the raw materials into a mixing kettle, stirring for 10-15 minutes at the temperature of 35-39 ℃ to enable the raw materials to be in a homogenate shape, standing for 2 hours to obtain the natural high-efficiency anti-hair loss pilatory, and bottling by using a rubber head dropper tool.

Preferably, the cannabidiol crude oil is industrial hemp or crude oil containing cannabidiol phenolic substances extracted from hemp by a dispersed solid phase extraction method, the argan oil is prepared by squeezing nuts on an argan tree or extracting the argan oil at a low temperature, the frankincense oil is prepared by extracting plants in Persivia, the tea tree oil is prepared by extracting tea trees, the bergamot oil is prepared by extracting citrus fruits growing on a bergamot orange tree, and the hemp seed oil is prepared by squeezing industrial hemp seeds.

Preferably, the castor oil is a triglyceride of fatty acids, and is prepared by squeezing or solvent extraction of castor seeds.

Preferably, the formula of the natural efficient anti-hair loss pilatory also contains vitamin E, and the vitamin E is prepared by squeezing or low-temperature extraction of nuts on the Argan tree.

The invention has the beneficial effects that:

(1) the invention prepares the natural high-efficiency anti-hair loss hair restorer by adopting the cannabidiol crude oil as the main raw material, which is beneficial to inhibiting the activity of 5-alpha reductase by the cannabidiol acting on receptors such as CB1 receptor, TRPV1 receptor, 5-HT1A receptor and the like in human body, thereby controlling the 5 alpha reductase to generate an androgen after the reaction with testosterone in the human body, and achieving the purpose of treating hair loss by reducing the androgen level.

The raw material effects are as follows:

cannabidiol crude oil: CBD oils have shown promise for the treatment of depression and anxiety, even in the safe treatment of insomnia and burning in post-traumatic stress disorder children; can alleviate symptoms associated with cancer, CBD may help reduce symptoms associated with cancer and side effects associated with cancer treatment, such as nausea, vomiting, and pain; can reduce acne, CBD oil may be helpful in treating acne because of its anti-inflammatory properties and ability to reduce sebum secretion; has neuroprotective effects, and the ability of CBD to act on endogenous cannabinoids and other brain signalling systems may be beneficial to patients with neurological diseases; beneficial to heart health, CBD may benefit heart health in a number of ways, including lowering blood pressure and preventing heart damage; CBD may contribute to diabetes, drug abuse, psychiatric disorders and certain types of cancer.

Argan oil: the product contains a large amount of essential fatty acid, unsaturated fatty acid and linoleic acid, and can be used for resisting skin inflammation, reducing acne, moisturizing skin, and delaying skin aging; the vitamin E contained in the hair conditioner can moisten hair and promote wound healing; it can also be used as a protective agent for liver or blood circulation, and can prevent hypercholesterolemia and arteriosclerosis; argan oil also contains phytosterols, which have not been found in other oils to date, and which are also anti-inflammatory agents, and are beneficial in arthritis and rheumatism.

Butter oil: boswellia essential oil helps to relieve stress and negative mood, it has anxiolytic and depressive capabilities, but unlike prescription drugs, it has no side effects or causes unnecessary drowsiness; can be used as bactericide and disinfectant for enhancing immune system function and preventing diseases.

Tea tree oil: has antibacterial, antiinflammatory, pore astringing, common cold, cough, rhinitis, asthma treating, dysmenorrhea improving, menoxenia and genital infection relieving effects; the tea tree essential oil has the effects of resisting bacteria and diminishing inflammation, and can quickly permeate hair follicles for conditioning; conditioning dark skin color; removing dandruff, solving the problems of dandruff, scalp and the like, and making hair look healthier; anti-inflammatory and gynecological inflammation eliminating effects; resisting aging, moistening skin, softening skin, and delaying aging.

Castor oil: natural laxatives, which can relieve temporary constipation; the natural moisturizing cream serves as a humectant and can be used for moistening skin; the castor oil can form a moist environment when being smeared on the wound, so that the wound is prevented from being dried, and the healing is promoted; anti-inflammatory, topical castor oil can relieve inflammation and pain; acne is reduced, and the acne can be effectively reduced by applying the ointment on the skin; combatting fungi, castor oil has antifungal properties, and may help to combat candidiasis and maintain oral health; the hair and scalp health is maintained, and regularly smearing fats such as castor oil on the hair helps to lubricate hair dryness, increase elasticity and reduce dandruff.

Bergamot oil: can relieve the stimulation on the scalp; can relieve anxiety and fatigue; against food poisoning, can effectively destroy the bacteria type causing food-borne diseases; reducing cholesterol.

Hemp oil: can generate nitric oxide in vivo, wherein the nitric oxide is a gas molecule and can expand and relax blood vessels, thereby reducing blood pressure and reducing the risk of heart disease; has therapeutic effect on eczema and xerosis cutis; is rich in a large amount of vegetable protein; can reduce premenstrual syndrome and climacteric symptoms; it is helpful for digestion.

Drawings

FIG. 1 is a schematic overhead view of an inventive female patient prior to use of the product;

FIG. 2 is a schematic overhead view of a female patient of the invention after three months of use of the product;

FIG. 3 is a schematic overhead view of a male patient of the invention prior to use of the product;

FIG. 4 is a schematic overhead view of a male patient of the invention after one month of use of the product;

FIG. 5 is a schematic overhead view of a male patient of the invention after three months of use of the product;

figure 6 is a schematic overhead view of a male patient of the invention after six months of use of the product.

Detailed Description

The present invention will be further described with reference to specific embodiments for the purpose of facilitating an understanding of technical means, characteristics of creation, objectives and functions realized by the present invention, but the following embodiments are only preferred embodiments of the present invention, and are not intended to be exhaustive. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative efforts belong to the protection scope of the present invention. The experimental methods in the following examples are conventional methods unless otherwise specified, and materials, reagents and the like used in the following examples are commercially available unless otherwise specified.

The first embodiment is as follows:

the invention provides a natural efficient anti-hair loss pilatory which comprises the following components in parts by weight: cannabidiol crude oil 5g, argan oil 3.1g, frankincense oil 5.4g, tea tree oil 3.1g, castor oil 2.6g, bergamot oil 5.4g and hemp seed oil 300ml, and the preparation method comprises:

s1, weighing the raw materials according to the formula, putting the raw materials into a mixing kettle, stirring for 13 minutes at the temperature of 37.77 ℃ to enable the raw materials to be in a homogenate shape, standing for 2 hours to obtain the natural high-efficiency anti-hair loss pilatory, and bottling by using a rubber head dropper.

Example two:

a natural high-efficiency anti-hair loss pilatory comprises the following components in parts by weight: 3.75g of cannabidiol crude oil, 2.33g of argan oil, 4.05g of frankincense oil, 2.33g of tea tree oil, 1.95g of castor oil, 4.05g of bergamot oil and 225ml of hemp seed oil, and the preparation method comprises the following steps:

s1, weighing the raw materials according to the formula, putting the raw materials into a mixing kettle, stirring for 12 minutes at the temperature of 37 ℃ to enable the raw materials to be in a homogenate shape, standing for 2 hours to obtain the natural efficient anti-hair loss pilatory, and bottling by using a rubber head dropper tool.

Example three:

a natural high-efficiency anti-hair loss pilatory comprises the following components in parts by weight: cannabidiol crude oil 5g, argan oil 3.72g, frankincense oil 6.48g, tea tree oil 3.72g, castor oil 3.12g, bergamot oil 6.48g and hemp seed oil 360ml, and the preparation method comprises the following steps:

s1, weighing the raw materials according to the formula, putting the raw materials into a mixing kettle, stirring for 14 minutes at the temperature of 39 ℃ to enable the raw materials to be in a homogenate shape, standing for 2 hours to obtain the natural efficient anti-hair loss pilatory, and bottling by using a rubber head dropper tool.

Example four:

the 5 alpha reductase is a membrane protease dependent on reduced coenzyme II (N ADPH) and functions to catalyze the conversion of testosterone (T) to dihydrotestosterone, which when accumulated to high levels in the prostate and skin can cause many pathological changes, such as benign prostatic hyperplasia, acne, male baldness, female hirsutism, etc.

5 alpha reductase inhibitors are a class of drugs that reduce dihydrotestosterone production by inhibiting the activity of 5 alpha reductase, are effective means for treating androgen-dependent diseases, and are also the primary approach to non-surgical treatment of prostatic hyperplasia. According to the preparation formulas of the natural high-efficiency anti-hair-loss pilatory in the first to third embodiments, the natural high-efficiency anti-hair-loss pilatory with different formula parts is prepared, a normal mouse is adopted to test the activity inhibition of the natural high-efficiency anti-hair-loss pilatory on 5 alpha reductase tested by the mouse, and the test method comprises the following steps:

taking five unhaired male mice with the same age and similar weight, taking samples in the first, the second and the third embodiment cases and two corn germ oil placebos, smearing the samples in the first, the second and the third embodiment cases and the corn germ oil in an unhairing area in the same time period every day, observing and recording the hair production condition, and observing and obtaining that the hair of the mice using the sample experimental group is remarkably increased, while the hair of the unhairing parts of the mice of the placebos does not have any remarkable change; the concentration of the dihydrotestosterone in the serum of the sample implementation group and the serum of the placebo group are detected in 30 days, 60 days, 90 days, 120 days, 150 days and 180 days respectively to obtain that the content of the dihydrotestosterone in the serum of the experimental group is reduced by 20-40% compared with the whole concentration of the placebo group, and the content of the dihydrotestosterone in the mice of the placebo group does not fluctuate obviously, so that the sample group plays a corresponding role in inhibiting the activity of 5 alpha reductase in the mice; the skin of the unhairing part of a mouse in a sample group is sampled at 180 days for slicing research, and the skin capillary vessels of the sample experimental group are obviously increased compared with those of a placebo control group, so that the high-efficiency anti-hair loss hair restorer is proved to have certain effect on the retention and growth of the capillary vessels, can promote the microcirculation of the skin and improve the skin environment, and the sampling test result data at 180 days are shown in the following table:

the HE staining test is carried out on the skin of the unhairing part of the sample group mouse and the skin of the sample group at 180 days, and the hair follicles of the sample group are found to be remarkably increased compared with those of a placebo control group, so that the high-efficiency anti-hair loss hair restorer sample is proved to have a great effect on promoting the growth of the hair follicles of the skin and can promote the hair restoration.

Example five:

according to the preparation formulas of the natural high-efficiency anti-hair loss hair restorer in the first to third embodiments, the natural high-efficiency anti-hair loss hair restorer with different formula parts is prepared, 600 volunteers with hair loss symptoms with sparse hair in the age range of 25-55 are tested, wherein 400 males and 200 females respectively use the natural anti-hair loss hair restorer and placebo, samples and the placebo in the embodiment cases are respectively dripped on hair loss parts, the samples and the placebo are massaged until being absorbed, a comparative test is carried out, the use lasts for 6 months, and the test result data are shown in the following table:

after the natural high-efficiency anti-hair loss pilatory is used for 1-6 months, the hair loss (55% -85%) can be obviously reduced, and the hair can be regenerated (65% -92%), so that the natural high-efficiency anti-hair loss pilatory has obvious effects of inhibiting hair loss and promoting hair growth.

In conclusion, the invention prepares the natural high-efficiency anti-hair loss hair restorer by adopting the cannabidiol crude oil as the main raw material, which is beneficial to inhibiting the activity of 5-alpha reductase by the cannabidiol acting on receptors such as CB1 receptor, TRPV1 receptor, 5-HT1A receptor and the like in human body, thereby controlling the 5 alpha reductase to generate an androgen after reacting with testosterone in the human body, and achieving the aim of treating hair loss by reducing the androgen level.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A natural high-efficiency anti-hair loss pilatory is characterized in that: the natural efficient anti-hair loss pilatory comprises the following components in parts by weight: 2.5g to 7.5g of cannabidiol crude oil, 1.55g to 4.65g of argan oil, 2.7g to 8.1g of frankincense oil, 1.55g to 4.65g of tea tree oil, 1.3g to 3.9g of castor oil, 2.7g to 8.1g of bergamot oil and 150ml to 450ml of hemp seed oil, and the preparation method comprises the following steps:

2. The natural efficient anti-hair loss hair restorer according to claim 1, wherein: the cannabidiol crude oil is prepared from industrial hemp or crude oil containing cannabidiol phenolic substances extracted from hemp by a dispersed solid phase extraction method, the argan oil is prepared by squeezing nuts on Argan or extracting at low temperature, the mastic oil is prepared by extracting plants in Persiviria, the tea tree oil is prepared by extracting tea trees, the bergamot oil is prepared by extracting citrus fruits growing on bergamot orange trees, and the hemp seed oil is prepared by extracting industrial hemp seeds.

3. The natural efficient anti-hair loss hair restorer according to claim 1, wherein: the castor oil is fatty acid triglyceride, and is prepared from castor seeds by squeezing or solvent extraction.

4. The natural efficient anti-hair loss hair restorer according to claim 1, wherein: the formula of the natural efficient anti-hair loss pilatory also contains vitamin E, and the vitamin E is prepared by squeezing or low-temperature extracting nuts on the Argan tree.