CN110652339A - Thrombus removing device - Google Patents
Thrombus removing device Download PDFInfo
- Publication number
- CN110652339A CN110652339A CN201910937411.6A CN201910937411A CN110652339A CN 110652339 A CN110652339 A CN 110652339A CN 201910937411 A CN201910937411 A CN 201910937411A CN 110652339 A CN110652339 A CN 110652339A
- Authority
- CN
- China
- Prior art keywords
- thrombus
- double
- hole
- recovery
- jet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3203—Fluid jet cutting instruments
- A61B17/32037—Fluid jet cutting instruments for removing obstructions from inner organs or blood vessels, e.g. for atherectomy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Surgical Instruments (AREA)
Abstract
The invention provides a thrombus clearing device, which belongs to the technical field of medical instruments and comprises: the recovery tube is provided with at least two thrombus recovery ports along the front-back direction on the side wall respectively, at least one double-circulation forming hole is formed in the middle of each thrombus recovery port, each double-circulation forming hole is provided with a first outlet facing the inner wall direction of the blood vessel and deviating to the front direction, and each double-circulation forming hole is also provided with a second outlet facing the inner wall direction of the blood vessel and deviating to the rear direction; the medicine feeding pipe is arranged in the recovery pipe and is provided with at least one jet hole, and the jet hole faces to an inlet of the double-circulation forming hole. According to the thrombus removing device provided by the invention, the liquid medicine is ejected from the jet hole and injected into the double-circulation forming hole and then is divided into two liquid medicine flows with different directions, the two liquid medicine flows can simultaneously remove thrombus on the vascular wall in the front and back directions, the impact area of the liquid medicine is increased, the advancing and retreating amplitude of the recovery tube in the blood vessel is reduced, and the thrombus removing efficiency is greatly accelerated.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a thrombus removal device.
Background
Mechanical thrombectomy is a means of treating a thrombus by delivering a thrombectomy device to the site of deep vein thrombosis and removing the blood clot by mechanical means. The traditional Chinese medicine composition has short curative effect and excellent curative effect, and is the most advanced and effective peripheral artery and vein thrombosis volume reduction technology at present.
Chinese patent document CN110049735A discloses a thrombus-clearing catheter, which comprises a fluid pulse generator, an outflow hole, an inflow hole, and a high-pressure tube, wherein the high-pressure tube is provided with an ejection hole, the fluid pulse generator is used to control the flow of a liquid medicine, and the liquid medicine is ejected from the ejection hole of the high-pressure tube, then ejected from the outflow hole, ejected from the thrombus-clearing catheter, and returned from the inflow hole into the thrombus-clearing catheter after clearing the thrombus, and then discharged outside the body.
However, in the thrombus removing device in the above scheme, since the thrombus on the blood vessel wall is removed by the single circulation, the cleaning area of the thrombus on the blood vessel wall by the single circulation is small, the cleaning efficiency is low, the operation duration is long, the operation risk is large, and the operation cost is high.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to overcome the defect of low thrombus removal efficiency of the thrombus removal device in the prior art, thereby providing the thrombus removal device.
In order to solve the above technical problem, the present invention provides a thrombus removal device, including:
the recovery tube is provided with at least two thrombus recovery ports along the front-back direction on the side wall respectively, at least one double-circulation forming hole is formed in the middle of each thrombus recovery port, each double-circulation forming hole is provided with a first outlet facing the inner wall direction of the blood vessel and deviating to the front direction, and each double-circulation forming hole is also provided with a second outlet facing the inner wall direction of the blood vessel and deviating to the rear direction;
the medicine feeding pipe is arranged in the recovery pipe and is provided with at least one jet hole, and the jet hole faces to an inlet of the double-circulation forming hole.
Preferably, the double circulation forming holes are provided in plurality in a circumferential direction of a tube wall of the recovery tube.
Preferably, a Y-shaped channel is provided in the double annular flow forming hole.
Preferably, the jet orifices are directed toward the inlet sidewall of the Y-shaped channel where the double annulus forms the orifice.
Preferably, the jet hole is arranged on the jet pipe, and the jet pipe is communicated with the medicine feeding pipe.
Preferably, the jet pipe is an annular pipe.
Preferably, the jet pipe is perpendicular to the medicine feeding pipe.
Preferably, the jet hole has a plurality of holes, and corresponds to the double loop current forming hole one to one.
Preferably, the head of the recovery pipe is tapered.
Preferably, the rear portion of the recovery tube is adapted to be connected to a recovery device. The technical scheme of the invention has the following advantages:
1. according to the thrombus removing device provided by the invention, the double-circulation forming hole is formed in the recovery tube, the thrombus recovery port is provided with the inlet and the two outlets with different directions, the liquid medicine is sprayed from the jet hole and is injected into the double-circulation forming hole and then is divided into two liquid medicine flows with different directions, and the two liquid medicine flows can simultaneously remove thrombus on the vascular wall in the front direction and the back direction, so that the impact area of the liquid medicine is increased, the thrombus removing efficiency is greatly accelerated, the advancing and retreating range of the recovery tube in the blood vessel is reduced, the operation duration can be reduced, and the operation risk is greatly reduced.
2. According to the thrombus removing device provided by the invention, the plurality of double-circulation forming holes are formed in the circumferential direction of the tube wall of the recovery tube, so that thrombus in the circumferential direction on the vessel wall can be simultaneously removed, the rotation amplitude of the recovery tube in the vessel is reduced, the removing efficiency of the thrombus removing device is further accelerated, the action amplitude of the recovery tube is reduced, the possibility that the thrombus removing device falls off from the vessel can be reduced, and the operation risk is reduced.
3. According to the thrombus removal device provided by the invention, the Y-shaped channel is arranged in the double-circulation forming hole, so that the structure of the double-circulation forming hole is simplified, and the manufacturing of the recovery tube is facilitated.
4. According to the thrombus removing device provided by the invention, the jet hole faces the inlet side wall of the Y-shaped channel of the double-circulation forming hole, so that the liquid medicine sprayed out of the jet hole is firstly sprayed to the side wall of the inlet of the double-circulation forming hole, the kinetic energy of the liquid medicine is reduced after the liquid medicine collides with the side wall, and then the liquid medicine is sprayed out of the double-circulation forming hole, the impact force of the liquid medicine on the blood vessel wall is reduced, and the medical accident caused by the fact that the liquid medicine breaks through the.
5. According to the thrombus removal device provided by the invention, the jet pipe is an annular pipe, so that the position of the jet hole can be randomly selected to adapt to the double-circulation formed hole.
6. According to the thrombus removal device provided by the invention, the jet pipe is vertical to the medicine feeding pipe, so that the liquid medicine injected from the jet hole can be conveniently controlled to be injected into the double-circulation forming hole.
7. According to the thrombus removal device provided by the invention, the plurality of jet holes correspond to the double-circulation forming holes one by one, so that one jet hole is matched with one double-circulation forming hole, and the thrombus removal efficiency is further accelerated.
8. According to the thrombus removing device provided by the invention, the head of the recovery tube is conical, and the advancing end of the recovery tube is thin, so that the recovery tube can conveniently advance in a blood vessel.
9. According to the thrombus removing device provided by the invention, the tail part of the recovery tube is suitable for being connected with the recovery equipment and is used for extracting the liquid medicine with thrombus residues after thrombus removal from the blood vessel, so that the liquid medicine is prevented from flowing along with blood, and the thrombus residues in the liquid medicine are accumulated at other parts in the body to cause danger.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
Fig. 1 is a schematic view of the operation of a thrombus removal device according to an embodiment of the present invention.
Fig. 2 is a schematic structural view of a thrombus removal device provided in an embodiment of the present invention.
Fig. 3 is a schematic structural view of a double loop current forming hole provided in an embodiment of the present invention.
Description of reference numerals: 1. a recovery pipe; 2. a medicine delivery pipe; 3. double loop forming a hole; 4. a thrombus retrieval port; 5. a jet pipe; 6. a jet hole; 7. thrombosis; 8. the wall of the blood vessel.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
Fig. 1 to 3 show an embodiment of the thrombus removal device provided in this embodiment, which includes: a recovery pipe 1 and a medicine feeding pipe 2.
A pair of thrombus recovery ports 4 are respectively arranged on the side wall of the recovery tube 1 along the front-back direction, the front-back direction is the advancing and retreating direction of the recovery tube 1 in a blood vessel, a double-circulation forming hole 3 is formed in the tube wall of the recovery tube 1 in the middle of the thrombus recovery ports 4, a Y-shaped channel is arranged in the double-circulation forming hole 3, a first outlet of the Y-shaped channel faces the direction of the inner wall of the blood vessel and is deviated to the front, and a second outlet of the Y-shaped channel faces the direction of the inner wall of the blood vessel and is deviated to the second outlet at the rear. Double circulation forms of hole 3 and is provided with threely along the pipe wall circumferencial direction of recovery tube 1, and thrombus is retrieved mouth 4 and is provided with three pairs along the pipe wall circumferencial direction of recovery tube 1, can reduce recovery tube 1 rotation range in the blood vessel and can accomplish to the thrombus 7 on the whole vascular wall 8 and clear away, has reduced the probability that thrombus 7 clearing device drops from the blood vessel, reduces the operation risk. The thrombus recovery port 4 corresponds to the double loop formation hole 3 in the front-rear direction.
1 inside of recovery tube is equipped with medicine conveying pipe 2, be connected with efflux pipe 5 on medicine conveying pipe 2, efflux pipe 5 and medicine conveying pipe 2 intercommunication, be equipped with three efflux hole 6, efflux hole 6 forms hole 3 one-to-one with the double-circulation, efflux hole 6 is arranged in spraying the liquid medicine to form hole 3 rather than the double-circulation that corresponds, efflux hole 6 sets up on efflux pipe 5, efflux pipe 5 is the toroidal tube and efflux pipe 5 and send medicine pipe 2 perpendicularly, efflux hole 6 forms the import lateral wall of the Y shape passageway of hole 3 towards the double-circulation. The head of the recovery tube 1 is conical, so that the recovery tube 1 can move forward in a blood vessel conveniently, the conical head of the recovery tube 1 is provided with an opening for balancing the internal and external pressures of the recovery tube 1, the situation that liquid medicine cannot accurately reach the inlet of the double-circulation forming hole 3 after being sprayed out from the jet hole 6 due to the unbalance of the internal and external pressures of the recovery tube 1 is avoided, the tail of the recovery tube 1 is suitable for being connected with recovery equipment, and the liquid medicine after the thrombus is cleared is conveniently taken out of the recovery tube 1.
When the thrombus removing operation is carried out, after the recovery tube 1 moves to a position to be removed of thrombus in a blood vessel, the liquid medicine flows to the jet pipe 5 from the medicine feeding pipe 2 by using external high-pressure liquid medicine conveying equipment, and is respectively sprayed out from the three jet holes 6 on the jet pipe 5 due to high pressure. The liquid medicine sprays to the lateral wall of 3 imports of dual-circulation formation of aperture department to take place irregular collision with 3 lateral walls of dual-circulation formation of aperture department at the import, reduce the kinetic energy of liquid medicine, prevent that the liquid medicine impact force is too big to break through vascular wall 8 and cause medical accident. As shown in fig. 1, the direction of the arrows in the figure is a flow path of the liquid medicine after being ejected from the jet hole 6, and the liquid medicine is ejected from two outlets of the Y-shaped channel of the double circulation hole 3 to form two circulation flows, and impacts the thrombus 7 deposited on the blood vessel wall 8 to remove the thrombus 7. After the thrombus 7 is removed by the liquid medicine, thrombus residues are carried into the thrombus recovery port 4 and are extracted out of the body from the recovery tube 1, so that the thrombus residues are prevented from accumulating in other parts of the body to form a new thrombus 7 after flowing along with blood. Because be equipped with a plurality of double circulation and form hole 3 and the liquid medicine can form along the circulation of two directions in front and back simultaneously and clear away thrombus 7 on the vascular wall 8 after spouting in the double circulation forms hole 3 on recovery tube 1, increased the area of clearing away of liquid medicine, reduced the action range that recovery tube 1 gos forward and retreat in the blood vessel simultaneously, can greatly improve thrombus and clear away efficiency, it is long to reduce the operation, reduces the operation risk.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.
Claims (10)
1. A thrombus removal device, comprising:
the recovery tube (1) is provided with at least two thrombus recovery ports (4) in the front-back direction on the side wall, at least one double-circulation forming hole (3) is formed in the middle of each thrombus recovery port (4), each double-circulation forming hole (3) is provided with a first outlet facing the inner wall direction of the vascular wall (8) and deviating to the front side, and each double-circulation forming hole (3) is further provided with a second outlet facing the inner wall direction of the vascular wall (8) and deviating to the rear side;
the medicine feeding pipe (2) is arranged inside the recovery pipe (1) and is provided with at least one jet hole (6), and the jet hole (6) faces to an inlet of the double-circulation forming hole (3).
2. The thrombectomy device according to claim 1, wherein the double loop forming holes (3) are provided in plurality along a circumferential direction of a wall of the recovery tube (1).
3. The thrombectomy device according to claim 1, wherein said double loop forming holes (3) are provided with Y-shaped channels.
4. The thrombectomy device according to claim 3, wherein said jet orifice (6) is directed towards the inlet side wall of the Y-shaped channel of said double annular flow forming orifice (3).
5. The thrombus removal device according to claim 1, wherein the jet hole (6) is provided on a jet pipe (5), the jet pipe (5) communicating with the drug delivery pipe (2).
6. The thrombectomy device according to claim 5, wherein said jet tube (5) is an annular tube.
7. The thrombectomy device according to claim 6, wherein said jet tube (5) is perpendicular to said drug delivery tube (2).
8. The thrombectomy device according to claim 6, wherein said jet orifice (6) has a plurality and is in one-to-one correspondence with said double loop forming holes (3).
9. The thrombectomy device according to claim 1, wherein the head of said recovery tube (1) is tapered.
10. A thrombectomy device according to claim 9, wherein the tail portion of said recovery tube (1) is adapted to be connected to a recovery apparatus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910937411.6A CN110652339B (en) | 2019-09-29 | 2019-09-29 | Thrombus removing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910937411.6A CN110652339B (en) | 2019-09-29 | 2019-09-29 | Thrombus removing device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110652339A true CN110652339A (en) | 2020-01-07 |
| CN110652339B CN110652339B (en) | 2020-06-30 |
Family
ID=69040140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910937411.6A Active CN110652339B (en) | 2019-09-29 | 2019-09-29 | Thrombus removing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110652339B (en) |
Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060129091A1 (en) * | 2004-12-10 | 2006-06-15 | Possis Medical, Inc. | Enhanced cross stream mechanical thrombectomy catheter with backloading manifold |
| CN101123918A (en) * | 2004-03-04 | 2008-02-13 | 施特劳勃医疗器械股份公司 | Catheter for sucking, fragmenting removing material extractable from blood vessels |
| NL1034242C2 (en) * | 2007-02-16 | 2008-08-19 | T M H Beheer B V | Catheter for removing blood clots, has radially oriented outlet openings for cleaning agent located in its head |
| CN101484203A (en) * | 2005-12-05 | 2009-07-15 | 梅德拉股份有限公司 | Exhaust-pressure-operated balloon catheter system |
| CN105209101A (en) * | 2013-03-14 | 2015-12-30 | 波士顿科学有限公司 | Thrombectomy catheters, systems and methods |
| CN105228536A (en) * | 2013-03-13 | 2016-01-06 | 波士顿科学有限公司 | Conduit system |
| CN206434388U (en) * | 2016-11-14 | 2017-08-25 | 惠州科赛医疗有限公司 | Medical cutter head structure and medical water jet apparatus |
| CN107496009A (en) * | 2017-10-16 | 2017-12-22 | 广东博迈医疗器械有限公司 | Vascular plaque cutter device |
| CN107693924A (en) * | 2017-05-17 | 2018-02-16 | 威海吉威重症医疗制品有限公司 | One kind blocks elimination type catheter |
| CN109157730A (en) * | 2018-08-29 | 2019-01-08 | 江苏省人民医院（南京医科大学第附属医院） | Catheter capable of being pressurized |
| CN110049735A (en) * | 2016-10-12 | 2019-07-23 | 波士顿科学国际有限公司 | Thrombus removes conduit |
| CN110038740A (en) * | 2019-05-22 | 2019-07-23 | 吴丹凯 | A kind of sluice gun rotary jet nozzle structure |
-
2019
- 2019-09-29 CN CN201910937411.6A patent/CN110652339B/en active Active
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101123918A (en) * | 2004-03-04 | 2008-02-13 | 施特劳勃医疗器械股份公司 | Catheter for sucking, fragmenting removing material extractable from blood vessels |
| US20060129091A1 (en) * | 2004-12-10 | 2006-06-15 | Possis Medical, Inc. | Enhanced cross stream mechanical thrombectomy catheter with backloading manifold |
| US20180092658A1 (en) * | 2004-12-10 | 2018-04-05 | Boston Scientific Limited | Enhanced cross stream mechanical thrombectomy catheter |
| CN101484203A (en) * | 2005-12-05 | 2009-07-15 | 梅德拉股份有限公司 | Exhaust-pressure-operated balloon catheter system |
| NL1034242C2 (en) * | 2007-02-16 | 2008-08-19 | T M H Beheer B V | Catheter for removing blood clots, has radially oriented outlet openings for cleaning agent located in its head |
| CN105228536A (en) * | 2013-03-13 | 2016-01-06 | 波士顿科学有限公司 | Conduit system |
| CN105209101A (en) * | 2013-03-14 | 2015-12-30 | 波士顿科学有限公司 | Thrombectomy catheters, systems and methods |
| CN110049735A (en) * | 2016-10-12 | 2019-07-23 | 波士顿科学国际有限公司 | Thrombus removes conduit |
| CN206434388U (en) * | 2016-11-14 | 2017-08-25 | 惠州科赛医疗有限公司 | Medical cutter head structure and medical water jet apparatus |
| CN107693924A (en) * | 2017-05-17 | 2018-02-16 | 威海吉威重症医疗制品有限公司 | One kind blocks elimination type catheter |
| CN107496009A (en) * | 2017-10-16 | 2017-12-22 | 广东博迈医疗器械有限公司 | Vascular plaque cutter device |
| CN109157730A (en) * | 2018-08-29 | 2019-01-08 | 江苏省人民医院（南京医科大学第附属医院） | Catheter capable of being pressurized |
| CN110038740A (en) * | 2019-05-22 | 2019-07-23 | 吴丹凯 | A kind of sluice gun rotary jet nozzle structure |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110652339B (en) | 2020-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1878582B (en) | Degassing device and end-cap assembly for a filter including such a degassing device | |
| JP3540868B2 (en) | Sand collecting nozzle device | |
| CN110652339B (en) | Thrombus removing device | |
| JP3938557B2 (en) | Bubble removal chamber having a function of preventing deformation of blood cell components | |
| JP5529710B2 (en) | Air trap chamber | |
| CN202970575U (en) | Blockage removing device adopting high-pressure jetting and negative-pressure pumping | |
| CN208641942U (en) | Backpulsing self-cleaning filter | |
| CN106102607A (en) | Liquid injection apparatus and operating theater instruments | |
| CN216495502U (en) | Catheter for taking thrombus | |
| JP6156851B2 (en) | Filtration device, spraying device including the same, and filtration method | |
| KR101957413B1 (en) | Jet ejecter for bag-filter of dust collector | |
| KR200486383Y1 (en) | Safety nozzle for cleaning nasal cavity and nasal cavity cleaning apparatus incorporating the same | |
| CN215465294U (en) | Blocking spray head | |
| CN110384536B (en) | Thrombus removing catheter and thrombus removing device with same | |
| CN208641979U (en) | Self-cleaning filter | |
| CN212788611U (en) | Thrombus clearing device | |
| CN211327928U (en) | Foam nozzle utilizing impact expansion | |
| CN218835358U (en) | Spinning jet belt cleaning device for hollow fiber membrane | |
| CN101524580A (en) | High expansion foam fire-extinguishing system | |
| CN215994817U (en) | Nose washing spray head and nose washing device | |
| CN217987972U (en) | Anti-backflow nose washing device | |
| CN218943437U (en) | Thrombus aspiration catheter | |
| CN220487525U (en) | Drilling cuttings cleaning device | |
| CN217569210U (en) | Shower nozzle with pulse strikes effect | |
| CN213347162U (en) | Nasal cavity flushing and sucking irrigator for nasal sinuses |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |