CN110639131A - Glasses type acousto-optic treatment equipment for Alzheimer's disease - Google Patents
Glasses type acousto-optic treatment equipment for Alzheimer's disease Download PDFInfo
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- CN110639131A CN110639131A CN201911083938.3A CN201911083938A CN110639131A CN 110639131 A CN110639131 A CN 110639131A CN 201911083938 A CN201911083938 A CN 201911083938A CN 110639131 A CN110639131 A CN 110639131A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C11/00—Non-optical adjuncts; Attachment thereof
- G02C11/10—Electronic devices other than hearing aids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A61M2021/0005—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
- A61M2021/0027—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0645—Applicators worn by the patient
- A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
- A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract
The invention discloses glasses type acousto-optic treatment equipment for Alzheimer's disease, which comprises a glasses type shell capable of being worn in front of eyes of a person, wherein two groups of LED light lamp groups, an audio output interface and a control circuit are arranged on the glasses type shell, the control circuit can control and generate a stroboscopic control signal of 1Hz-100Hz and transmit the stroboscopic control signal to an LED lamp to enable the stroboscopic control signal to be ceaselessly stroboscopic, and can also control a sound generation module to generate a sound signal of 10KHz-20KHz, and the signal is output to a volume output interface after being amplified by power; the device can effectively reduce the accumulation of amyloid A beta of the Alzheimer's disease patient, activate microglia, reduce nerve entanglement, enhance the brain waves (especially gamma brain waves) of the patient, has good effects on treating, relieving and inhibiting the Alzheimer's disease, and effectively improves the cognitive ability and the memory ability of the patient. In addition, the equipment integrates acousto-optic treatment and glasses, is portable and light and handy to wear, and is more acceptable by patients; and the operation is simple, and even the patient can use the device by himself.
Description
Technical Field
The invention relates to a device for treating Alzheimer's disease, in particular to a glasses type acousto-optic treatment device for Alzheimer's disease.
Background
At present, the Alzheimer disease is mainly treated by medicines to prevent the accumulation of amyloid A beta, but the effects are not obvious and have corresponding side effects; researches show that the accumulation of amyloid A beta can be slowed down through behavior perception such as light stimulation and the like, and the preparation has a positive effect on treating the Alzheimer's disease. The existing acousto-optic treatment equipment is often large in size, complex to operate and not portable enough when in use, and the eyes of a user are required to be completely shielded, so that the use is not comfortable enough, and the user experience is not good; the invention combines the acousto-optic treatment with the conventional glasses, and can achieve the optimal use effect and the auxiliary treatment effect through the structural design.
Disclosure of Invention
The invention aims to provide glasses type acousto-optic treatment equipment for Alzheimer's disease, which can be used for assisting in solving the problems of unobvious treatment effect and side effect of the existing medicines. The therapeutic apparatus has the advantages of portability, noninvasive treatment, no side effect and the like. Based on the principle of behavior cognitive stimulation, one mechanism is that light of 1Hz-100Hz (especially 40Hz) continuously flickers to act on eyeballs, so that A beta amyloid protein accumulation is prevented, microglia is activated, nerve fiber entanglement is relieved, and gamma brain waves are enhanced; the other mechanism is that the sound of 10kHz-20kHz (especially the sound of 10 kHz) acts on the auditory sense, the accumulation of amyloid A beta is prevented, microglia is absorbed, the entanglement of nerve fibers is relieved, and the gamma brain wave is stabilized.
The technical scheme of the invention is as follows:
an eyeglass type Alzheimer's disease acousto-optic treatment device comprises an eyeglass type shell which can be worn to the front of the eyes of a person, two groups of LED lamp sets, an audio output interface and a control circuit are arranged on the glasses type shell, the two groups of LED lamps respectively correspond to the left eye and the right eye, each group comprises a plurality of LED lamps, the normal line of each LED lamp is aligned with the corresponding eyeball, because the optic nerve of the human is mainly in the macular area at the bottom of the eyeball, the arrangement can lead the light to be intensively irradiated on the optic nerve of the eyeball to achieve the best effect, the control circuit comprises a sound generation module, the control circuit is used for generating a stroboscopic control signal of 1Hz-100Hz and transmitting the stroboscopic control signal to the LED lamp to enable the stroboscopic control signal to be continuously stroboscopic, the control circuit is also used for controlling the sound generation module to generate a sound signal of 10KHz-20KHz, and the sound signal is output to the volume output interface after being amplified by power.
Among the above-mentioned technical scheme, glasses type casing include printing opacity lens, shell, flexible circuit board, inner cup in proper order, control the temple and press from both sides, wholly constitute the glasses shape, correspond the both eyes and seted up two mirror holes respectively on shell and the inner cup, the printing opacity lens covers outside the mirror hole of shell, LED banks is installed on flexible circuit board, the fixed clamp of flexible circuit board is arranged in between shell and the inner cup and is made LED banks be located the mirror hole position. The light-transmitting lens can be configured into a convex lens or a concave lens according to requirements so as to correct the vision of a patient.
Furthermore, the inner cover is also provided with a nose support with adjustable height. The nose support can adopt a hole column structure, such as: the top of each wing of the nose support is fixedly connected with a column body into a whole, a protrusion for limiting is arranged on the column body, a longitudinal limiting hole for inserting the column body is formed in the inner cover, a plurality of limiting grooves are formed in the wall of the inner cover below the limiting hole from top to bottom, and the nose support can be adjusted up and down through the matching of the adjusting protrusion and the limiting grooves with different heights.
Furthermore, the inner sides of the left temple clamp and the right temple clamp are provided with soft glue layers.
Furthermore, the distance between the LED lamp set and human eyes is 5-40 mm. The optimal distance is about 20mm according to the light source characteristics and the experimental effect.
Further, the control circuit specifically contain power module, the base frequency generation module, stroboscopic signal generation module, LED array control module, sound power amplification module, volume control and audio output module, the base frequency generation module is used for producing a stable high accuracy clock signal, direct output gives stroboscopic signal generation module and sound generation module, stroboscopic signal generation module produces 1Hz-100 Hz's stroboscopic control signal and exports for LED array control module control LED banks, sound generation module produces 10KHz-20 KHz's sound signal, through sound power amplification circuit, output to volume control and volume output module from volume output interface output.
The invention has the beneficial effects that:
the device has good effects of treating, relieving and inhibiting the Alzheimer disease, and the output stroboscopic signal and the audio signal can effectively reduce the accumulation of amyloid A beta of the Alzheimer disease patient after the Alzheimer disease patient uses the device for a period of time, activate microglia, reduce nerve entanglement, effectively improve the cognitive ability and the memory ability of the patient, and enhance the gamma brain wave of the patient. The equipment integrates acousto-optic treatment and glasses, is portable and light and handy to wear, and is more acceptable by patients; and the operation is simple, and even the patient can use the device by himself.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below, it is obvious that the drawings in the following description are only embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic diagram showing a specific structure of the apparatus of the present invention;
FIG. 2 is an overall block diagram and usage diagram of the apparatus of the present invention;
FIG. 3 is a control schematic of the apparatus of the present invention;
FIG. 4 is an enlarged detail view of the apparatus of FIG. 1;
FIG. 5 is a schematic view of an LED lamp arrangement;
fig. 6 is a specific structure diagram of the nose pad.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
As shown in fig. 1 and 2, the glasses type alzheimer disease acousto-optic treatment device comprises a glasses type shell, wherein the shell sequentially comprises a light-transmitting lens, a shell, a flexible circuit board, an inner cover, a left temple clamp and a right temple clamp, the glasses shape is integrally formed, the glasses type acousto-optic treatment device can be directly worn in front of two eyes like wearing glasses, the device further comprises two groups of LED lamp sets, an audio output interface and a control circuit, two glasses holes are respectively formed in the shell and the inner cover corresponding to the two eyes, the light-transmitting lens covers the outside of the glasses holes of the shell, the LED lamp sets are arranged on the flexible circuit board, the two groups of LED lamp sets respectively correspond to the left eye and the right eye, each group comprises a plurality of LED lamps, the normal line of each LED lamp is aligned with the direct visual nerve of the corresponding eyeball (as shown in fig. 5), the LED lamp sets are 5-40 mm away from the eyes, and the distance is optimal. The flexible circuit board is fixedly clamped between the outer shell and the inner cover, and the LED lamp set is located at the position of the lens hole. The control circuit comprises a sound generation module, the control circuit is used for generating a stroboscopic control signal of 1Hz-100Hz and transmitting the stroboscopic control signal to the LED lamp to enable the stroboscopic control signal to be continuously stroboscopic, the control circuit is also used for controlling the sound generation module to generate a sound signal of 10KHz-20KHz, and the sound signal is output to the volume output interface after being amplified by power. The use of acoustic signals does not produce excessive stimulation of the patient.
The control circuit can include a power module, a fundamental frequency generation module, a stroboscopic signal generation module, an LED array control module, a sound power amplification module, a volume adjustment module and an audio output module, and the following models or types can be specifically selected for each module: a fundamental frequency generation module (SN74AHC1G04DBVR, Ti; crystal oscillator 20 KHz-100 KHz), a stroboscopic signal generation module (CD4017B, Ti; CD4518B, Ti), an LED array control module (FDV301N, ON), a sound generation module (CD4020B, Ti; AiP555, Wuxi I-CORE; SN74LVC1G79DBVR, Ti; GS8722, a polyglove semiconductor), a sound power amplification module (LPA4890, LowPowerSemi), a volume adjustment and audio output module (GS8722, a polyglove semiconductor), a power management module (AP2007, Chipown; GS2019-TR, a polyglove semiconductor), a lithium ion battery management module (TP4057-42-SOT26-R, TOPPOWER (Nanjing Tuo micro)), and the like. The working principle is as follows: the base frequency generation module generates a stable high-precision clock signal of 1 KHz-100 KHz based on the crystal oscillator oscillation circuit, the signal is directly output to the stroboscopic signal generation module and the sound generation module, and a stroboscopic control signal of 1Hz-100Hz is generated and output to the LED array control module through the stroboscopic signal generation module and a frequency division circuit in the sound generation module; generating a square wave signal of 10KHz-20KHz, filtering the square wave signal to generate a sound signal, outputting the sound signal to a sound power amplifying circuit, adjusting the volume of the sound signal, outputting the sound signal to an audio output interface, and finally generating sound by an earphone and transmitting the sound signal to a patient; the power management module comprises an LDO and a DC/DC, wherein the LDO is used for generating 3.3V direct current voltage required by control circuits such as a signal generation circuit and the like, and the DC/DC is used for generating voltage required by the LED array control module; the lithium ion management module is used for controlling the charging management of the lithium ion battery.
In addition, the inner cover is also provided with a nose support with adjustable height. The nose pad can adopt a hole column structure, and fig. 6 shows a specific structural schematic of the nose pad, such as: the top of each wing of the nose support is fixedly connected with a column body into a whole, a protrusion for limiting is arranged on the column body, a longitudinal limiting hole for inserting the column body is formed in the inner cover, a plurality of limiting grooves are formed in the wall of the inner cover below the limiting hole from top to bottom, and the nose support can be adjusted up and down through the matching of the adjusting protrusion and the limiting grooves with different heights.
In order to be more comfortable to wear, the inner sides of the left temple and the right temple are provided with soft adhesive layers. The clear lenses may also be configured as either convex or concave lenses as desired to correct the patient's vision. The glasses type shell can also be provided with a volume adjusting key, an on-off key and the like.
Claims (7)
1. A glasses type Alzheimer disease acousto-optic treatment device is characterized by comprising a glasses type shell capable of being worn in front of eyes of a person, wherein two groups of LED lamp sets, an audio output interface and a control circuit are arranged on the glasses type shell, the two groups of LED lamp sets respectively correspond to a left eye and a right eye, each group of the LED lamp sets comprises a plurality of LED lamps, the normal line of each LED lamp is aligned to a corresponding eyeball, the control circuit comprises a sound generation module, the control circuit is used for generating a stroboscopic control signal of 1Hz-100Hz and transmitting the stroboscopic control signal to the LED lamps to enable the stroboscopic control signal to be ceaselessly stroboscopic, and the control circuit is also used for controlling the sound generation module to generate a sound signal of 10KHz-20KHz, and the sound signal is output to a volume; the glasses type shell comprises a light-transmitting lens, a shell, a flexible circuit board, an inner cover, a left temple clamp and a right temple clamp in sequence, the glasses type shell integrally forms a glasses shape, two glasses holes are formed in the shell and the inner cover corresponding to two eyes respectively, the light-transmitting lens covers the outside of the glasses holes of the shell, an LED lamp bank is installed on the flexible circuit board, and the flexible circuit board is fixedly clamped between the shell and the inner cover and enables the LED lamp bank to be located at the positions of the glasses holes.
2. The glasses type Alzheimer's disease acousto-optic treatment device according to claim 1, wherein the LED lamp set is 5-40 mm away from human eyes.
3. The glasses-type alzheimer's disease audio-visual therapy apparatus according to claim 1, wherein said control circuit comprises a power module, a base frequency generation module, a strobe signal generation module, an LED array control module, a sound power amplification module, a volume adjustment and audio output module, wherein the base frequency generation module is configured to generate a stable high-precision clock signal and directly output the clock signal to the strobe signal generation module and the sound generation module, the strobe signal generation module generates a 1Hz to 100Hz strobe control signal and outputs the strobe control signal to the LED array control module to control the LED light set, the sound generation module generates a 10KHz to 20KHz sound signal, and the sound signal is output to the volume adjustment and volume output module through the sound power amplification circuit and is output from the volume output interface.
4. The eyeglass-type alzheimer's disease acousto-optic treatment device according to claim 1, wherein a height-adjustable nose pad is further provided on the inner cap.
5. The glasses type Alzheimer's disease acousto-optic treatment device according to claim 4, wherein the nose pad adopts a hole column structure, the tops of two wings of the nose pad are fixedly connected with a column body, the column body is provided with a protrusion for limiting, the inner cover is provided with a longitudinal limiting hole for inserting the column body, a plurality of limiting grooves are arranged on the wall of the inner cover below the limiting hole from top to bottom, and the up-and-down adjustment of the nose pad is realized by matching the adjusting protrusion with the limiting grooves with different heights.
6. The apparatus according to claim 1, wherein the transparent lens is configured as a convex or concave lens to correct the vision of the patient.
7. The eyeglass type alzheimer's disease acousto-optic treatment device according to claim 1, wherein soft gel layers are provided on inner sides of the left and right temples.
Priority Applications (1)
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CN201911083938.3A CN110639131A (en) | 2019-11-07 | 2019-11-07 | Glasses type acousto-optic treatment equipment for Alzheimer's disease |
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CN201911083938.3A CN110639131A (en) | 2019-11-07 | 2019-11-07 | Glasses type acousto-optic treatment equipment for Alzheimer's disease |
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CN201911083938.3A Pending CN110639131A (en) | 2019-11-07 | 2019-11-07 | Glasses type acousto-optic treatment equipment for Alzheimer's disease |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113101493A (en) * | 2021-05-08 | 2021-07-13 | 宁波市康宁医院(宁波市精神疾病预防控制中心、宁波市微循环与莨菪类药研究所) | Adjustable-frequency Alzheimer disease improvement eyeshade |
CN113332612A (en) * | 2021-07-06 | 2021-09-03 | 北京大学深圳医院 | Acousto-optic physiotherapy instrument based on 40 Hz frequency spectrum |
-
2019
- 2019-11-07 CN CN201911083938.3A patent/CN110639131A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113101493A (en) * | 2021-05-08 | 2021-07-13 | 宁波市康宁医院(宁波市精神疾病预防控制中心、宁波市微循环与莨菪类药研究所) | Adjustable-frequency Alzheimer disease improvement eyeshade |
CN113332612A (en) * | 2021-07-06 | 2021-09-03 | 北京大学深圳医院 | Acousto-optic physiotherapy instrument based on 40 Hz frequency spectrum |
CN113332612B (en) * | 2021-07-06 | 2024-05-03 | 北京大学深圳医院 | Acousto-optic physiotherapy instrument based on 40 Hz frequency spectrum |
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