CN110623807A - Animal operation box capable of simulating high-stress environment - Google Patents
Animal operation box capable of simulating high-stress environment Download PDFInfo
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- CN110623807A CN110623807A CN201910902865.XA CN201910902865A CN110623807A CN 110623807 A CN110623807 A CN 110623807A CN 201910902865 A CN201910902865 A CN 201910902865A CN 110623807 A CN110623807 A CN 110623807A
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- 241001465754 Metazoa Species 0.000 title claims abstract description 32
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract description 34
- 238000004088 simulation Methods 0.000 claims abstract description 22
- 238000012544 monitoring process Methods 0.000 claims abstract description 20
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract description 17
- 239000001569 carbon dioxide Substances 0.000 claims abstract description 17
- 238000010438 heat treatment Methods 0.000 claims abstract description 13
- 238000005192 partition Methods 0.000 claims description 12
- 238000009434 installation Methods 0.000 claims description 9
- 239000011521 glass Substances 0.000 claims description 8
- 239000004973 liquid crystal related substance Substances 0.000 claims description 5
- 230000005611 electricity Effects 0.000 claims description 4
- 238000005057 refrigeration Methods 0.000 claims description 4
- 230000017525 heat dissipation Effects 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 2
- 238000010171 animal model Methods 0.000 description 6
- 230000000638 stimulation Effects 0.000 description 6
- 230000007613 environmental effect Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 230000035939 shock Effects 0.000 description 3
- 230000035943 smell Effects 0.000 description 3
- 230000003925 brain function Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 230000001919 adrenal effect Effects 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000027288 circadian rhythm Effects 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 230000006999 cognitive decline Effects 0.000 description 1
- 208000010877 cognitive disease Diseases 0.000 description 1
- 238000005094 computer simulation Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G10/00—Treatment rooms or enclosures for medical purposes
- A61G10/02—Treatment rooms or enclosures for medical purposes with artificial climate; with means to maintain a desired pressure, e.g. for germ-free rooms
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- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cold Air Circulating Systems And Constructional Details In Refrigerators (AREA)
- Greenhouses (AREA)
Abstract
An animal operation box capable of simulating a high-stress environment comprises an operation box body, an environment simulation assembly and a monitoring camera, wherein the operation box body is sequentially divided into a control top box, a middle box body and a supporting bottom box from top to bottom, the middle box body is used for placing animals, the environment simulation assembly comprises an LED lamp, a sound, a carbon dioxide gas concentration monitor and a small refrigerating and heating all-in-one machine, the LED lamp, the sound and the carbon dioxide gas concentration monitor are arranged in the middle box body, the small refrigerating and heating all-in-one machine is arranged in the supporting, the humidifier and the gas cylinder are arranged outside the operation box body, the middle box body is formed by enclosing a left baffle, a right baffle and a rear baffle, the front face of the middle box body is provided with an operation door, a triangular fixing plate is arranged at the intersection of adjacent plate walls on the inner side of the middle box body, an LED lamp and a monitoring camera are mounted at the top of the middle box body, a sound and a carbon dioxide concentration monitor are arranged on the left baffle, and a corresponding pipeline mounting hole is formed in the middle of the right baffle; the invention simulates high stress environment through different stimulus combinations, and has simple and convenient operation, strong applicability and high practicability.
Description
Technical Field
The invention relates to the field of biological experiment devices, in particular to an animal operation box capable of simulating a high-stress environment.
Background
The earth has complex geographical climatic environments such as equator, two poles, desert, wetland, deep sea and the like, animals and people can show different physiological and pathological states under extreme environments from those at ordinary times, and high stress states are generated by combining negative emotions such as fear and tension, so that the level of hormones such as glucocorticoid and adrenal hormone is increased, and the change of brain function levels such as anxiety, depression, cognitive decline and the like can be caused; however, the currently marketed animal operation box capable of simulating a specific environment has the defects of single simulation object, deficient simulation technology, difficulty in dynamic simulation and the like, and is difficult to continuously and dynamically simulate a complex real environment, so that the experimental research in the aspect is relatively lagged behind, and further improvement on the animal operation box is needed.
Disclosure of Invention
The invention aims to solve the technical problem of providing an animal operation box which can be provided with different stimulation combinations and dynamically and vividly simulate a specific high-stress environment.
The technical scheme adopted by the invention for solving the technical problems is as follows: the animal operation box capable of simulating the high-stress environment comprises an operation box body, an environment simulation assembly and a monitoring camera, wherein the operation box body is sequentially divided into a control top box, a middle box body and a supporting bottom box from top to bottom, the middle box body is used for placing animals, the environment simulation assembly comprises an LED lamp, a sound device and a carbon dioxide gas concentration monitor which are arranged inside the middle box body, a small refrigerating and heating all-in-one machine which is arranged inside the supporting bottom box, and a humidifier and a gas cylinder which are arranged outside the operation box body, and the LED lamp is a light source capable of adjusting brightness; the middle box body is formed by enclosing a left baffle, a right baffle and a rear baffle, an operation door is arranged on the front face of the middle box body, the middle part of the operation door is rectangular transparent glass, and a shutter device is arranged on the outer side of the transparent glass; a triangular fixing plate is fixedly arranged at the intersection of adjacent plate walls on the inner side of the middle box body, four triangular fixing plates are arranged on the same horizontal plane, a plurality of layers of triangular fixing plates are arranged in the vertical direction, a movable partition plate is arranged on the triangular fixing plates, and the movable partition plate is a rectangular plate provided with a plurality of through holes; the LED lamp and the monitoring camera are mounted at the top of the middle box body, the sound and the carbon dioxide concentration monitor are detachably mounted on the left baffle, the humidifier pipeline mounting hole is formed in the middle of the right baffle, the humidifier pipeline mounting hole is communicated with an external humidifier after a pipeline is mounted, a gas cylinder pipeline mounting hole is further formed in the middle of the right baffle, the gas cylinder pipeline mounting hole is communicated with an external gas cylinder after the pipeline is mounted, an electric wire mounting hole is further formed below the humidifier pipeline mounting hole, and an electric wire of the monitoring camera is externally connected with a power supply through the electric wire mounting hole;
the top surface of the supporting bottom box is provided with an air outlet, the front surface of the supporting bottom box is provided with an equipment installation door, and the equipment installation door is provided with a plurality of strip-shaped heat dissipation holes;
the control top box openly is provided with the operating panel who is used for adjusting parameter, last function button and the liquid crystal display window of being equipped with of operating panel, the inside control module who is connected with the operating panel electricity that is provided with of control top box, control module is connected with LED lamp, stereo set, carbon dioxide gas concentration monitor, surveillance camera head and small-size refrigeration heating all-in-one electricity respectively.
Furthermore, the animal operation box capable of simulating the high-stress environment further comprises an external computer, and the monitoring camera is electrically connected with the external computer.
Further, the environment simulation assembly further comprises an electric shock box, and electric wires of the electric shock box are communicated with an external power supply through the electric wire mounting holes; the electric shock box is electrically connected with the external computer.
Further, the environment simulation assembly further comprises an pungent smell object, and the pungent smell object is placed at the bottom of the middle box body.
Further, the monitoring camera uses an infrared camera.
Furthermore, rubber seal rings with cross-shaped patterns at the middle parts are arranged at the humidifier pipeline mounting hole, the gas cylinder pipeline mounting hole and the electric wire mounting hole.
Compared with the prior art, the animal operation box capable of simulating the high-stress environment controls the temperature and the humidity through the small refrigerating and heating integrated machine and the external humidifier, so that the condition parameters are more conveniently and accurately controlled; the LED lamp is arranged at the top of the operation box, and illumination can be adjusted through the operation panel to realize circadian rhythm simulation; the box body is reserved with a gas cylinder pipeline mounting hole which can be connected with a gas cylinder; the concentration of the gas in the box is monitored by a carbon dioxide gas concentration monitor, so that the simulation dynamic state of the gas is adjustable; the box is internally provided with a sound box, and the audio playing is controlled through the operation panel, so that the simulation of various noise environments with noise can be realized; an electric shock box can be placed in the box, is controlled by an external computer, controls the stimulation intensity, time and frequency of foot sole electric shock through software, and can simulate unforeseen stimulation conditions; objects with different pungent smells can be placed at the bottom in the box, so that the environmental simulation factors are diversified; the monitoring equipment is arranged to monitor the behavior of the experimental animal under the condition that the experimental animal is not influenced, and in addition, the adjustment of the movement range of the animal is realized through the height-adjustable partition plate; the animal operation box capable of simulating the high-stress environment provided by the invention can simulate specific high-stress environments such as deep sea exploration, tropical work and the like through different stimulation combinations, provides an experimental device for researching the change rule of the hormone and brain function level of animals in the environments and enabling human bodies to better adapt to the high-stress environments, and is very practical.
Drawings
Fig. 1 is a front view (operation door open state) of an animal operation box capable of simulating a high stress environment according to the present invention.
Fig. 2 is a front view of an animal handling box (a closed state of the handling door) capable of simulating a high stress environment according to the present invention.
Figure 3 is a front view of the invention when placed in the shock box.
Reference numerals: 1-operating a box body; 11-control the top box; 111-an operating panel; 1111-function buttons; 1112-a liquid crystal display window; 12-a middle box; 121-left baffle; 122-right baffle; 1221-humidifier pipeline mounting holes; 1222-gas cylinder pipe installation hole; 1223-wire mounting holes; 123-a rear baffle; 124-operating the door; 1241-transparent glass; 1242-shutter device plate; 126-a movable partition; 13-supporting the bottom case; 131-an air outlet; 132-equipment mounting door; 133-strip-shaped heat dissipation holes; (ii) a 125-triangle fixed 2-environment simulation components; 21-an LED lamp; 22-sound box; 23-a carbon dioxide gas concentration monitor; 24-a humidifier; 25-a gas cylinder; 26-electric shock box; 3-a monitoring camera; 4-external computer;
Detailed Description
The invention is described in further detail below with reference to the accompanying examples.
As shown in fig. 1 to 3, the animal operation box capable of simulating a high stress environment comprises an operation box body 1, an environment simulation assembly 2 and a monitoring camera 3, wherein the operation box body 1 is sequentially divided into a control top box 11, a middle box body 12 and a support bottom box 13 from top to bottom, the middle box body 12 is used for placing animals, the environment simulation assembly 2 comprises an LED lamp 21, a sound box 22, a carbon dioxide gas concentration monitor 23, a small refrigerating and heating integrated machine (not shown in the figure) arranged inside the support bottom box 13, and a humidifier 24 and a gas cylinder 25 arranged outside the operation box body 1, the LED lamp 21 is selected from a light source capable of adjusting brightness, and the gas cylinder 25 can be selected from a gas cylinder 25 containing corresponding gas according to experimental requirements; the middle box body 12 is formed by enclosing a left baffle 121, a right baffle 122 and a rear baffle 123, the front face of the middle box body 12 is provided with an operating door 124, the middle part of the operating door 124 is rectangular transparent glass 1241, a louver device 1242 is arranged outside the transparent glass 1241, and the transparent glass 1241 is arranged to observe the internal situation through opening and closing the louver device without influencing the state of the experimental animal; a triangular fixing plate 125 is fixedly arranged at the intersection of adjacent plate walls on the inner side of the middle box body 12, four triangular fixing plates 125 are arranged on the same horizontal plane, a plurality of layers of triangular fixing plates 125 are arranged in the vertical direction, a movable partition plate 126 is arranged on the triangular fixing plates 125, the movable partition plate 126 can be arranged on the triangular fixing plates 125 at different heights according to the body types or experimental requirements of different animals, and the movable partition plate 126 is a rectangular plate provided with a plurality of through holes; LED lamp 21 and surveillance camera head 3 are installed at middle part box 12 top, demountable installation has stereo set 22 and carbon dioxide gas concentration monitor 23 on the left baffle 121, humidifier pipeline mounting hole 1221 has been seted up at right baffle 122 middle part, be used for installing the pipeline, communicate outside humidifier 24, gas cylinder pipeline mounting hole 1222 has still been seted up with humidifier pipeline mounting hole 1221 parallel and level in right baffle 122 middle part, gas cylinder pipeline mounting hole 1222 is used for installing the pipeline, be used for communicating outside gas cylinder 25, an electric wire mounting hole 1223 has still been seted up to humidifier pipeline mounting hole 1221 below, LED lamp 21, stereo set 22, the electric wire accessible electric wire mounting hole 1223 external power supply of electrical apparatus such as surveillance camera head 3, LED lamp 21, stereo set 22, carbon dioxide gas concentration monitor 23 also can adopt rechargeable, increase the cleanliness.
Support inside the under casing 13 and placed small-size refrigeration and heating all-in-one, support the top surface of under casing 13 and seted up air outlet 131, support under casing 13 openly and be provided with equipment fixing door 132 for open and put into small-size refrigeration and heating all-in-one and make things convenient for the maintenance of equipment, seted up a plurality of bar louvres 133 on the equipment fixing door 132.
The front of the control top box 11 is provided with an operation panel 111, the operation panel 111 is provided with a function button 1111 and a liquid crystal display window 1112, the control top box 11 is internally provided with a control module (not shown in the figure) electrically connected with the operation panel 111, the control module is respectively and electrically connected with the LED lamp 21, the sound box 22, the carbon dioxide concentration monitor 23, the monitoring camera 3 and the small-sized refrigerating and heating all-in-one machine, the setting of each parameter can be carried out on the operation panel 111, namely, the illumination intensity of the LED lamp 21 can be adjusted through the function button 1111 in combination with the display of the liquid crystal display window 1112, the audio playing of the sound box 22 is controlled, the value of the carbon dioxide concentration monitor 23 is displayed in real time, the monitoring camera 3 is turned on or off, and the temperature output of the small-sized refrigerating and heating all-in-one machine.
Preferably, the animal operation box capable of simulating the high-stress environment further comprises an external computer 4, and the monitoring camera 3 is electrically connected with the external computer 4 so as to observe the activity condition of the animal in real time through the monitoring camera 3.
Preferably, the environmental simulation assembly 2 further includes an electric shock box 26 and an irritant odor object (not shown in the figure), the operation door 124 can be opened, and the electric shock box 26 is placed in the electric shock box 26, the electric shock box 26 is a transparent box body, which belongs to the prior art, the specific structure is not described again, the electric wire of the electric shock box 26 is inserted into the electric wire installation hole 1223, and is connected to an external power supply, so that the operation can be realized; the shock box 26 is electrically connected to the external computer 4, and the stimulation intensity, time and frequency of the shock are controlled by the external computer 4 so as to simulate unforeseen stimulation conditions.
Preferably, the pungent odor substance is placed at the bottom of the middle housing 12, below the movable partition 126, in order to add more variables and make the environmental simulation factor more varied.
Preferably, the monitoring camera 3 uses an infrared camera, can better capture the motion state of the animal, and can monitor the behavior of the experimental animal under the state that the experimental animal is not influenced.
Preferably, rubber sealing rings (not shown in the figure) with cross patterns in the middle are installed at the humidifier pipeline installation hole 1221, the gas cylinder pipeline installation hole 1222 and the electric wire installation hole 1223, so that a space with better gas tightness is created when the gas cylinder 25 is opened, and meanwhile, the passing of pipelines and electric wires is not affected.
The working process of the invention is as follows: opening the operation door 124, adjusting the height of the movable partition 126, placing the experimental animal on the movable partition 126 of the middle box body 12, closing the operation door 124, adjusting various parameters such as brightness of the LED lamp 21 on the operation panel 111 of the control top box 11, and pulling the shutter device 1242 open when observation is needed; when needed, the pungent odor object is put into the electric shock box 26, and an experimental environment with more variables is created.
In addition, the LED lamp 21, the sound box 22, the carbon dioxide gas concentration monitor 23, the small-sized refrigerating and heating integrated machine, the humidifier 24 and the gas cylinder 25 are all the prior art, and the specific structure is not repeated.
Finally, it should be noted that: the above examples are merely illustrative of the technical solutions of the present invention, and not limitative thereof; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (6)
1. Can simulate animal control box of high stress environment, its characterized in that: the environment simulation device comprises an operation box body (1), an environment simulation assembly (2) and a monitoring camera (3), wherein the operation box body (1) is sequentially divided into a control top box (11), a middle box body (12) and a supporting bottom box (13) from top to bottom, the middle box body (12) is used for placing animals, the environment simulation assembly (2) comprises an LED lamp (21), a sound (22) and a carbon dioxide concentration monitor (23) which are arranged inside the middle box body (12), a small refrigerating and heating all-in-one machine arranged inside the supporting bottom box (13), a humidifier (24) and an air bottle (25) which are arranged outside the operation box body (1), and the LED lamp (21) is selected from a light source with adjustable brightness; the middle box body (12) is formed by enclosing a left baffle (121), a right baffle (122) and a rear baffle (123), an operation door (124) is arranged on the front face of the middle box body (12), the middle of the operation door (124) is rectangular transparent glass (1241), and a shutter device (1242) is arranged on the outer side of the transparent glass (1241); a triangular fixing plate (125) is fixedly arranged at the intersection of adjacent plate walls on the inner side of the middle box body (12), four triangular fixing plates (125) are arranged on the same horizontal plane, a plurality of layers of triangular fixing plates (125) are arranged in the vertical direction, a movable partition plate (126) is placed on each triangular fixing plate (125), and the movable partition plate (126) is a rectangular plate provided with a plurality of through holes; the LED lamp (21) and the monitoring camera (3) are mounted at the top of the middle box body (12), a sound (22) and a carbon dioxide concentration monitor (23) are detachably mounted on the left baffle (121), a humidifier pipeline mounting hole (1221) is formed in the middle of the right baffle (122), the humidifier pipeline mounting hole (1221) is communicated with an external humidifier (24) after a pipeline is mounted, a gas cylinder pipeline mounting hole (1222) is further formed in the middle of the right baffle (122), the gas cylinder pipeline mounting hole (1222) is communicated with an external gas cylinder (25) after the pipeline is mounted, a wire mounting hole (1223) is further formed below the humidifier pipeline mounting hole (1221), and a wire of the monitoring camera (3) is externally connected with a power supply through the wire mounting hole (1223);
an air outlet (131) is formed in the top surface of the supporting bottom box (13), an equipment mounting door (132) is arranged on the front surface of the supporting bottom box (13), and a plurality of strip-shaped heat dissipation holes (133) are formed in the equipment mounting door (132);
control top case (11) openly are provided with operating panel (111) that are used for adjusting parameter, be equipped with function button (1111) and liquid crystal display window (1112) on operating panel (111), control top case (11) inside is provided with the control module who is connected with operating panel (111) electricity, control module is connected with LED lamp (21), stereo set (22), carbon dioxide gas concentration monitor (23), surveillance camera head (3) and small-size refrigeration heating all-in-one electricity respectively.
2. The animal operation box capable of simulating high stress environment according to claim 1, characterized in that the animal operation box capable of simulating high stress environment further comprises an external computer (4), and the monitoring camera (3) is electrically connected with the external computer (4).
3. The animal handling box capable of simulating a high stress environment according to claim 2, wherein the environment simulation assembly (2) further comprises an electric shock box (26), and electric wires of the electric shock box (26) are communicated with an external power supply through the electric wire installation hole (1223); the electric shock box (26) is electrically connected with the external computer (4).
4. The animal handling box capable of simulating a high stress environment according to claim 1, wherein the environment simulation module (2) further comprises pungent odor objects placed at the bottom of the middle box body (12).
5. The animal handling box capable of simulating a high stress environment according to claim 1, wherein the monitoring camera (3) uses an infrared camera.
6. The animal operation box capable of simulating the high-stress environment according to claim 1, wherein rubber sealing rings with cross-shaped patterns in the middle are mounted at the humidifier pipeline mounting hole (1221), the gas cylinder pipeline mounting hole (1222) and the electric wire mounting hole (1223).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910902865.XA CN110623807A (en) | 2019-09-24 | 2019-09-24 | Animal operation box capable of simulating high-stress environment |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910902865.XA CN110623807A (en) | 2019-09-24 | 2019-09-24 | Animal operation box capable of simulating high-stress environment |
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| CN110623807A true CN110623807A (en) | 2019-12-31 |
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| CN201910902865.XA Pending CN110623807A (en) | 2019-09-24 | 2019-09-24 | Animal operation box capable of simulating high-stress environment |
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Cited By (3)
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| CN111296307A (en) * | 2020-02-12 | 2020-06-19 | 南开大学 | Small animal behavior track acquisition device |
| CN112237156A (en) * | 2020-10-23 | 2021-01-19 | 宁波大学 | Device and experimental method for testing autonomous social behaviors of small animals |
| CN114403018A (en) * | 2021-12-31 | 2022-04-29 | 西安交通大学 | Stress experiment system |
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Application publication date: 20191231 |
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| RJ01 | Rejection of invention patent application after publication |