CN110613812A - Traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin and preparation method thereof - Google Patents
Traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin and a preparation method thereof, wherein the traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin adopts semen raphani, perilla fruit, semen pharbitidis, elecampane, immature bitter orange, agilawood, liquorice, fried hawthorn, prepared rhubarb, fried malt, prepared cyperus rotundus, fried medicated leaven, ginger processed pinellia tuber, poria cocos, coptis chinensis, fructus gardeniae, gallnut, fingered citron and radix linderae as main raw materials and is subjected to proper weight proportion, and the traditional Chinese medicine composition with effects of treating dyspepsia, gastrointestinal heat accumulation, constipation, abdominal distension and monophagia and anorexia is finally prepared. The preparation method of the traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin is simple to operate, the effective components of the raw material components can be retained to the maximum extent, and the prepared traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin has good effects of promoting digestion, removing food retention, relaxing bowels and expelling toxin.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin and a preparation method thereof.
Background
Food retention refers to a disease of traditional Chinese medicine, and mainly refers to a gastrointestinal disease formed by excessive food intake, damage to the spleen and stomach and retention of food in the middle-jiao. Dyspepsia is also a clinical syndrome, a disease caused by gastric motility disorder, and also includes gastroparesis and esophageal reflux disease, which have poor gastric motility. Dyspepsia is mainly classified into functional dyspepsia and organic dyspepsia. Functional dyspepsia belongs to the categories of epigastric fullness, stomachache, epigastric upset and the like in the traditional Chinese medicine, the diseases of the functional dyspepsia are in the stomach, relate to organs such as the liver and the spleen, and are treated by syndrome differentiation and treatment, and the treatment is performed by methods of strengthening the spleen and stomach, soothing the liver and regulating qi, promoting digestion and removing stagnation and the like. The main manifestations of constipation are a decrease in the number of stools and difficulty in defecation, with many patients having less than 3 stools per week, and severe patients having stools for 2-4 weeks. Some patients can obviously show difficult defecation, the defecation time can be more than 30 minutes, or the defecation is carried out for a plurality of times every day, but the defecation is difficult, and the feces are hard like sheep feces and are few in quantity. In addition, abdominal distension, anorexia, and abdominal pain before defecation due to improper administration of laxatives.
The incidence of gastroenteropathy and constipation in people is extremely high, and along with the change of the living mode of modern people, the incidence is also greatly increased, the existing medicine with the functions of removing food retention and defecation on the market has poor effect or large side effect, and the medicine with obvious effect and small side effect is urgently needed to meet the requirements of people.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin and a preparation method thereof. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin can effectively treat related diseases such as dyspepsia, gastrointestinal heat retention, constipation, abdominal distension, monophagia, anorexia and the like.
The technical scheme adopted by the invention is as follows:
a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin comprises the following raw material components:
1-13 parts of radish seed, 2-15 parts of perilla seed, 2-10 parts of pharbitis seed, 1-8 parts of costustoot, 1-13 parts of immature bitter orange, 0.5-5.5 parts of agilawood, 1-8 parts of liquorice, 2-10 parts of fried hawthorn, 1-8 parts of prepared rhubarb, 1-10 parts of fried malt, 5-10 parts of prepared cyperus rotundus, 4-10 parts of fried medicated leaven, 2-15 parts of ginger processed pinellia, 2-15 parts of poria cocos, 3-10 parts of coptis chinensis, 2-10 parts of black gardenia, 1-13 parts of gallnut, 2-13 parts of fingered citron and 1-10 parts of combined spicebush root.
Further preferably, the traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin comprises the following raw material components:
2-5 parts of radish seed, 2-4 parts of perilla seed, 3-5 parts of pharbitis seed, 1-3 parts of costustoot, 2-4 parts of immature bitter orange, 0.5-1.5 parts of agilawood, 1-3 parts of liquorice, 2-5 parts of fried hawthorn, 1-4 parts of prepared rhubarb, 1-6 parts of fried malt, 5-7 parts of prepared cyperus rotundus, 4-6 parts of fried medicated leaven, 2-5 parts of ginger processed pinellia, 2-4 parts of poria cocos, 3-5 parts of coptis chinensis, 2-6 parts of black gardenia, 1-3 parts of gallnut, 2-5 parts of fingered citron and 1-3 parts of combined spicebush root.
Further preferably, the traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin comprises the following raw material components:
3 parts of radish seed, 3 parts of perilla seed, 4 parts of pharbitis seed, 2 parts of costustoot, 3 parts of immature bitter orange, 1 part of agilawood, 2 parts of liquorice, 3 parts of fried hawthorn, 2 parts of prepared rhubarb, 2 parts of fried malt, 6 parts of prepared nutgrass galingale rhizome, 5 parts of fried medicated leaven, 3 parts of ginger processed pinellia tuber, 3 parts of tuckahoe, 4 parts of coptis root, 3 parts of black gardenia, 2 parts of gallnut, 3 parts of fingered citron and 2 parts of radix linderae.
The fried hawthorn is prepared by the following method:
cleaning and drying the hawthorn, frying the hawthorn with slow fire, then frying the hawthorn with strong fire, taking out the hawthorn and cooling the hawthorn to obtain the fried hawthorn.
Further, the stir-frying time is 10-30min, and the stir-frying temperature is 50-70 ℃; the stir-frying time is 5-10min, and the stir-frying temperature is 90-120 ℃.
Furthermore, the preparation method of the fried malt and the fried medicated leaven is the same as that of the fried hawthorn.
The prepared rhubarb is prepared by the following method:
cleaning radix et rhizoma Rhei, air drying, soaking in yellow wine, taking out the soaked radix et rhizoma Rhei, adding crystal sugar and water, and parching with slow fire to obtain the radix et rhizoma Rhei preparata.
The yellow wine soaking time is 1-2h, the mass ratio of the rock candy, the water and the rhubarb is 1:1 (2-4), the slow fire frying temperature is 60-70 ℃, and the slow fire frying time is 20-30 min.
Further, the preparation method of the processed cyperus rotundus is the same as the preparation method of the processed rhubarb.
A method for preparing the traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin comprises the following steps:
(1) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water, mixing and grinding respectively, adding malic acid for acidification, and then adding yeast for fermentation respectively to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(2) respectively frying the pharbitis seed, the costustoot and the immature bitter orange in parts by weight with slow fire to obtain fried pharbitis seed, fried costus root and fried immature bitter orange;
(3) soaking agilawood and liquorice in honey water respectively according to the weight parts, airing, and frying with slow fire to obtain honey-fried agilawood and honey-fried liquorice respectively;
(4) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; and adding honey into the mixture to prepare pills to obtain the traditional Chinese medicine composition with the effects of removing food stagnation, relaxing bowels and expelling toxin.
Further, in the step (1), the mass ratio of the water adding mass to the corresponding raw materials is 1 (1-2), the mass ratio of the malic acid to the corresponding raw materials is 1 (5-8), the acidification time is 6-7h, the mass ratio of the yeast to the corresponding raw materials is 1 (5-8), the fermentation temperature is 36-38 ℃, and the fermentation time is 20-30 days.
Further, in the step (2), the stir-frying time is 10-30min, and the stir-frying temperature is 60-70 ℃.
Further, in the step (3), the honey water is a mixed system of refined honey and boiling water in a mass ratio of 1 (2-5), and the mass ratio of the agilawood or the liquorice to the honey water is (3-5) to 1; the stir-frying time is 30-40min, and the stir-frying temperature is 60-70 ℃.
Further, in the step (4), the particle size after the crushing is 200-500 meshes, and the mass ratio of the honey to the mixture is 1 (5-7).
The invention discloses a brief introduction of the efficacy of each traditional Chinese medicine:
radish seed, pungent in flavor, neutral in nature, enters lung, spleen and stomach meridians, and has the following functions: descending qi and resolving phlegm, oppression in the chest and food stagnation, promoting digestion and resolving food stagnation, moving qi and relieving distension, and is used for abdominal distention and pain caused by food stagnation and qi stagnation, and strong qi-moving and stagnation-removing force, such as the tendency of falling wall and rushing wall.
Perilla fruit, fructus Perillae, with pungent taste and warm nature, enters lung and large intestine meridians, and is commonly used for descending qi and resolving phlegm, moistening dryness and smoothing intestine, and descending and purging lung qi to help large intestine conduction, and is used for constipation due to intestinal dryness and constipation, and constipation due to improper qi transformation.
Bai Chong and Black Chong, bitter in taste and cold in nature, entering lung, kidney and large intestine meridians, can purge and expel water, relieve constipation to expel dampness, resolve swelling and remove mass, treat tympanites due to abdominal distention, mass accumulated in the umbilicus and cord-on-cord mass in the hypochondrium, and have the actions of dissipating and removing stasis.
Licorice root, radix Glycyrrhizae is sweet in taste and warm in nature, enters heart, lung and spleen meridians, and is combined in a prescription to harmonize properties and cooperate with other herbs.
The costustoot is bitter in taste and warm in nature, enters spleen, stomach, large intestine, gallbladder and triple energizer channels, is fragrant and warm in passing, is good at passing qi stagnation of spleen and stomach, is a key medicine for promoting qi circulation, harmonizing stomach, strengthening spleen and promoting digestion, is commonly used for regulating qi activity, is used for various qi stagnation syndromes, can lower lung qi and soothe liver qi, and is a common medicine for treating lung qi loss, dispersion and descending and liver qi loss.
Chenxiang is pungent and bitter in flavor and warm in nature, enters spleen, stomach and kidney meridians, has descending weight, and can lower qi, check adverse flow of qi, warm middle energizer, dispel cold, warm spleen and stomach, and treat abdominal distending pain due to stomach cold and qi stagnation. Can be used for treating constipation caused by lung qi deficiency.
Immature bitter orange, bitter in taste, pungent and sour in flavor, enters spleen, stomach and large intestine channels, is good at breaking qi and relieving stuffiness, and removing food retention and removing stagnation, and treats abdominal fullness and distending pain, food stagnation, qi breaking, stagnation moving and phlegm reduction, and strong and violent force, and breaks stagnation just like wall-rushing and wall-falling.
Parched fructus crataegi is sour and sweet in taste, is slightly warm, enters spleen, stomach and liver channels, and has effects of resolving food stagnation, dispelling blood stasis and expelling tapeworm. It is used for treating meat stagnation, abdominal mass, phlegm retention, abdominal distention, acid regurgitation, dysentery, intestinal wind, lumbago, infantile colic, abdominal pain, lochiorrhea, and infantile dyspepsia. Promote digestion, invigorate stomach, promote qi circulation and dissipate blood stasis. Can be used for treating dyspepsia, flatulence, dysentery, abdominal pain, blood stasis, amenorrhea, puerperal stagnation, heart and abdominal pain, hernia pain, and hyperlipidemia.
Prepared rhubarb, bitter in taste and cold in flavor, enters stomach, large intestine and liver channels, purges heat toxin, breaks food stagnation and moves blood stasis. Treating excessive heat constipation, delirium, fever, food stagnation, abdominal fullness, dysentery, tenesmus, stasis, amenorrhea, abdominal mass, epidemic heat, acute conjunctivitis, hematemesis, epistaxis, yang jaundice, edema, stranguria with turbid urine, carbuncle, sore, and injury due to fire and dampness.
Roasted malt, sweet in flavor and slightly warm, enters spleen and stomach meridians, promotes digestion, regulates the middle warmer and purges qi. It is indicated for indigestion, abdominal distention, anorexia, vomiting, diarrhea and distention of the breast.
Prepared cyperus rotundus, pungent, slightly bitter and sweet, calm, enter liver and triple energizer meridians, regulate qi, relieve depression, relieve pain and regulate menstruation. It is indicated for disharmony of liver and stomach, qi stagnation, distending pain in chest, abdomen and hypochondrium, phlegm and fluid retention, irregular menstruation, metrorrhagia, metrostaxis and leukorrhagia.
The fried medicated leaven is sweet and pungent in flavor and warm, enters spleen and stomach channels, strengthens spleen and stomach, and digests food and regulates middle energizer. It is indicated for food stagnation, fullness in chest, abdominal distention, emesis, dysentery, puerperal abdominal pain due to blood stasis, and abdominal mass and accumulation in children.
Ginger processed pinellia tuber, rhizoma Pinelliae is pungent in flavor and warm in nature, enters spleen, stomach and lung meridians, and has the effects of eliminating dampness and phlegm, lowering adverse qi and relieving vomiting, relieving distension and fullness and resolving masses. Can be used for treating cough with asthma due to excessive phlegm, dizziness and palpitation due to phlegm and fluid retention, dizziness due to wind-phlegm, headache due to phlegm syncope, emesis, regurgitation, chest and gastric fullness, and globus hystericus.
Poria, sweet, bland and neutral in flavor, enters heart, lung, spleen and kidney meridians, induces diuresis and excrets dampness, invigorates spleen and calms heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Coptis root, rhizoma Coptidis, being cold in nature and bitter in taste, enters heart, spleen, stomach, liver, gallbladder and large intestine meridians, and is indicated for clearing heat and drying dampness, purging fire and removing toxicity, for damp-heat fullness, vomiting and acid regurgitation, dysentery, jaundice, high fever and coma, hyperactivity of heart-fire, hematemesis and epistaxis, conjunctival congestion, toothache, diabetes, carbuncle and furuncle.
Black gardenia, bitter and cold in taste, enters heart, lung and triple energizer channels, purges fire and relieves restlessness, clears heat and promotes diuresis, cools blood and detoxifies. Can be used for treating vexation due to fever, jaundice, dark urine, stranguria with blood, pain, hematemesis, epistaxis, conjunctival congestion, swelling and pain, and pyocutaneous disease due to pathogenic fire; it can be used for treating sprain, contusion and pain.
Galla chinensis, sour, astringent and cold in flavor, enters lung, large intestine and kidney meridians, astringes lung to reduce pathogenic fire, astringes intestine to check diarrhea, astringes sweat to stop bleeding, astringes dampness to heal wound. Can be used for treating chronic cough due to lung deficiency, chronic diarrhea, night sweat, diabetes, hemafecia, hemorrhoid, traumatic hemorrhage, carbuncle, sore, and skin ulcer.
The fingered citron, pungent, bitter and sour in taste and warm in nature, enters liver, spleen and lung channels, soothes liver, regulates qi, harmonizes stomach and relieves pain. Can be used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach, anorexia, and emesis.
Wu Yao, pungent and warm in flavor, enters lung, spleen, kidney and bladder meridians, guides qi downward to alleviate pain, warms kidney to dispel cold. Can be used for treating abdominal distention and pain, asthma, bladder deficiency cold, enuresis, frequent micturition, hernia, and dysmenorrhea.
The invention has the beneficial effects that:
the traditional Chinese medicine composition with the effects of removing food stagnation, relaxing bowels and expelling toxin is prepared by adopting radish seeds, perilla seeds, pharbitis seed, costustoot, immature bitter orange, agilawood, liquorice, fried hawthorn, prepared rhubarb, fried malt, prepared cyperus rotundus, fried medicated leaven, ginger processed pinellia tuber, poria cocos, coptis chinensis, black gardenia, gallnut, fingered citron and combined spicebush root as main raw materials in a proper weight ratio, and finally the traditional Chinese medicine composition with the effects of treating dyspepsia, gastrointestinal heat accumulation, constipation, abdominal distension and monophagia anorexia is prepared. The recipe takes the pharbitis seed, the prepared cyperus rotundus and the fried medicated leaven as monarch drugs, and has the effects of relaxing bowels, removing food retention and eliminating stagnation; semen raphani and immature bitter orange are used as ministerial drugs to help white pharbitis seed and black pharbitis seed to break food retention and remove flatulence, and eliminate phlegm and dispel water; radix aucklandiae, lignum Aquilariae Resinatum, fructus crataegi preparata, radix et rhizoma Rhei preparata, fructus Hordei Germinatus preparata, ginger processed pinellia Tuber, Poria, Coptidis rhizoma, fructus Gardeniae, Galla chinensis and fructus Citri Sarcodactylis as guiding drugs, and has effects of activating qi-flowing, warming spleen and stomach, dispelling cold, regulating qi-flowing and relieving pain; the liquorice and the combined spicebush root are used for coordinating the ingredients of the recipe to play the roles of helping digestion and relaxing the bowels. The preparation method of the traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin is simple to operate, the effective components of the raw material components can be retained to the maximum extent, and the prepared traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin has good effects of promoting digestion, removing food retention, relaxing bowels and expelling toxin.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In the following examples 1g is represented by 1 part by weight.
Example 1
The embodiment provides a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, which comprises the following raw material components:
1 part of radish seed, 2 parts of perilla seed, 2 parts of pharbitis seed, 1 part of costustoot, 1 part of immature bitter orange, 0.5 part of agilawood, 1 part of liquorice, 2 parts of fried hawthorn, 1 part of prepared rhubarb, 1 part of fried malt, 5 parts of prepared cyperus rotundus, 4 parts of fried medicated leaven, 2 parts of ginger processed pinellia, 2 parts of poria cocos, 3 parts of coptis chinensis, 2 parts of black gardenia, 1 part of gallnut, 2 parts of fingered citron and 1 part of combined spicebush root.
Further, the present embodiment provides a preparation method of the traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, including the following steps:
(1) preparing parched fructus crataegi, parched fructus Hordei Germinatus and parched Massa Medicata Fermentata
Cleaning fructus crataegi, air drying, parching with slow fire at 50 deg.C for 10min, parching with strong fire at 90 deg.C for 5min, taking out, and cooling to obtain the parched fructus crataegi;
(2) preparing prepared rhubarb and prepared nutgrass galingale rhizome
Cleaning and air drying rhubarb, adding yellow wine for soaking for 1-2h, taking out the soaked rhubarb, adding crystal sugar and water, frying for 20min at 60 ℃ with slow fire, wherein the mass ratio of the crystal sugar to the water to the rhubarb is 1:1:2, and thus obtaining the prepared rhubarb;
(3) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water with the same mass respectively, mixing and grinding, adding malic acid which accounts for 1/8 of the weight of each raw material, acidifying for 6 hours, then adding yeast which accounts for 1/8 of the weight of each raw material, and fermenting for 20 days at the fermentation temperature of 36 ℃ to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(4) respectively parching semen Pharbitidis, radix aucklandiae and fructus Aurantii Immaturus at 60 deg.C with slow fire for 10min to obtain parched semen Pharbitidis, parched radix aucklandiae and parched fructus Aurantii Immaturus;
(5) mixing and diluting the refined honey and the boiling water according to the mass ratio of 1:2 to obtain honey water, taking the agilawood and the liquorice according to the weight parts, respectively adding the honey water accounting for 1/5 of the mass of the raw materials to soak, airing, and frying for 30min at 60 ℃ with slow fire to respectively obtain the agilawood fried with honey and the liquorice fried with honey;
(6) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing to particle size of 200 mesh, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; adding 1/7 mass of Mel into the mixture, and making into pill to obtain the Chinese medicinal composition with effects of resolving food stagnation, relaxing bowels and removing toxic substance.
Example 2
The embodiment provides a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, which comprises the following raw material components:
13 parts of radish seed, 15 parts of perilla seed, 10 parts of pharbitis seed, 8 parts of costustoot, 13 parts of immature bitter orange, 5.5 parts of agilawood, 8 parts of liquorice, 10 parts of fried hawthorn, 8 parts of prepared rhubarb, 10 parts of fried malt, 10 parts of prepared cyperus rotundus, 10 parts of fried medicated leaven, 15 parts of ginger processed pinellia tuber, 15 parts of poria cocos, 10 parts of coptis chinensis, 10 parts of black gardenia, 13 parts of gallnut, 13 parts of fingered citron and 10 parts of combined spicebush root.
Further, the present embodiment provides a preparation method of the traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, including the following steps:
(1) preparing parched fructus crataegi, parched fructus Hordei Germinatus and parched Massa Medicata Fermentata
Cleaning fructus crataegi, air drying, parching at 70 deg.C below with strong fire for 30min, parching at 120 deg.C with strong fire for 10min, taking out, and cooling to obtain the parched fructus crataegi;
(2) preparing prepared rhubarb and prepared nutgrass galingale rhizome
Cleaning and airing rheum officinale, adding yellow wine for soaking for 2 hours, taking out the soaked rheum officinale, adding crystal sugar and water, and stir-frying for 30min at the temperature of 70 ℃ with a fire, wherein the mass ratio of the crystal sugar to the water to the rheum officinale is 1:1:4, so as to obtain the prepared rheum officinale;
(3) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water which accounts for 1/2 of the weight of each raw material respectively, mixing and grinding, adding malic acid which accounts for 1/5 of the weight of each raw material, acidifying for 7 hours, then adding yeast which accounts for 1/5 of the weight of each raw material respectively, and fermenting for 30 days at the fermentation temperature of 38 ℃ to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(4) respectively parching semen Pharbitidis, radix aucklandiae and fructus Aurantii Immaturus at 70 deg.C for 30min to obtain parched semen Pharbitidis, parched radix aucklandiae and parched fructus Aurantii Immaturus;
(5) mixing refined honey and boiling water at a mass ratio of 1:5 to dilute to obtain honey water, taking agilawood and liquorice according to the weight parts, respectively adding the honey water accounting for 1/3 of the mass of the raw materials to soak, airing, and stir-frying for 40min at 70 ℃ with fire to respectively obtain honey-fried agilawood and honey-fried liquorice;
(6) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing to particle size of 500 mesh, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; adding 1/5 mass of Mel into the mixture, and making into pill to obtain the Chinese medicinal composition with effects of resolving food stagnation, relaxing bowels and removing toxic substance.
Example 3
The embodiment provides a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, which comprises the following raw material components:
3 parts of radish seed, 3 parts of perilla seed, 4 parts of pharbitis seed, 2 parts of costustoot, 3 parts of immature bitter orange, 1 part of agilawood, 2 parts of liquorice, 3 parts of fried hawthorn, 2 parts of prepared rhubarb, 2 parts of fried malt, 6 parts of prepared nutgrass galingale rhizome, 5 parts of fried medicated leaven, 3 parts of ginger processed pinellia tuber, 3 parts of tuckahoe, 4 parts of coptis root, 3 parts of black gardenia, 2 parts of gallnut, 3 parts of fingered citron and 2 parts of radix linderae.
Further, the present embodiment provides a preparation method of the traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, including the following steps:
(1) preparing parched fructus crataegi, parched fructus Hordei Germinatus and parched Massa Medicata Fermentata
Cleaning fructus crataegi, air drying, parching with slow fire at 60 deg.C for 20min, parching with strong fire at 105 deg.C for 7.5min, taking out, and cooling to obtain the parched fructus crataegi;
(2) preparing prepared rhubarb and prepared nutgrass galingale rhizome
Cleaning and air drying rhubarb, adding yellow wine for soaking for 1.5h, taking out the soaked rhubarb, adding crystal sugar and water, and frying for 25min at the temperature of 65 ℃ with slow fire, wherein the mass ratio of the crystal sugar to the water to the rhubarb is 1:1:3, thus obtaining the prepared rhubarb;
(3) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water which accounts for 2/3 of the weight of each raw material respectively, mixing and grinding, adding malic acid which accounts for 1/7 of the weight of each raw material, acidifying for 6.5 hours, then adding yeast which accounts for 1/7 of the weight of each raw material respectively, and fermenting for 25 days at the fermentation temperature of 37 ℃ to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(4) respectively parching semen Pharbitidis, radix aucklandiae and fructus Aurantii Immaturus at 65 deg.C with slow fire for 20min to obtain parched semen Pharbitidis, parched radix aucklandiae and parched fructus Aurantii Immaturus;
(5) mixing and diluting the refined honey and the boiling water according to the mass ratio of 1:4 to obtain honey water, taking the agilawood and the liquorice according to the weight parts, respectively adding the honey water accounting for 1/4 of the mass of the raw materials to soak, airing, and frying for 35min at the temperature of 65 ℃ with fire to respectively obtain the agilawood fried with honey and the liquorice fried with honey;
(6) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing to 350 mesh, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; adding 1/6 mass of Mel into the mixture, and making into pill to obtain the Chinese medicinal composition with effects of resolving food stagnation, relaxing bowels and removing toxic substance.
Example 4
The embodiment provides a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, which comprises the following raw material components:
2 parts of radish seed, 2 parts of perilla seed, 3 parts of pharbitis seed, 1 part of costustoot, 2 parts of immature bitter orange, 0.5 part of agilawood, 1 part of liquorice, 2 parts of fried hawthorn, 1 part of prepared rhubarb, 1 part of fried malt, 5 parts of prepared cyperus rotundus, 4 parts of fried medicated leaven, 2 parts of ginger processed pinellia, 2 parts of poria cocos, 3 parts of coptis chinensis, 2 parts of black gardenia, 1 part of gallnut, 2 parts of fingered citron and 1 part of combined spicebush root.
Further, the present embodiment provides a preparation method of the traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, including the following steps:
(1) preparing parched fructus crataegi, parched fructus Hordei Germinatus and parched Massa Medicata Fermentata
Cleaning fructus crataegi, air drying, parching with slow fire at 50 deg.C for 10min, parching with strong fire at 90 deg.C for 5min, taking out, and cooling to obtain the parched fructus crataegi;
(2) preparing prepared rhubarb and prepared nutgrass galingale rhizome
Cleaning and air drying rhubarb, adding yellow wine for soaking for 1-2h, taking out the soaked rhubarb, adding crystal sugar and water, frying for 20min at 60 ℃ with slow fire, wherein the mass ratio of the crystal sugar to the water to the rhubarb is 1:1:2, and thus obtaining the prepared rhubarb;
(3) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water with the same mass respectively, mixing and grinding, adding malic acid which accounts for 1/8 of the weight of each raw material, acidifying for 6 hours, then adding yeast which accounts for 1/8 of the weight of each raw material, and fermenting for 20 days at the fermentation temperature of 36 ℃ to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(4) respectively parching semen Pharbitidis, radix aucklandiae and fructus Aurantii Immaturus at 60 deg.C with slow fire for 10min to obtain parched semen Pharbitidis, parched radix aucklandiae and parched fructus Aurantii Immaturus;
(5) mixing and diluting the refined honey and the boiling water according to the mass ratio of 1:2 to obtain honey water, taking the agilawood and the liquorice according to the weight parts, respectively adding the honey water accounting for 1/5 of the mass of the raw materials to soak, airing, and frying for 30min at 60 ℃ with slow fire to respectively obtain the agilawood fried with honey and the liquorice fried with honey;
(6) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing to particle size of 200 mesh, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; adding 1/7 mass of Mel into the mixture, and making into pill to obtain the Chinese medicinal composition with effects of resolving food stagnation, relaxing bowels and removing toxic substance.
Example 5
The embodiment provides a traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, which comprises the following raw material components:
5 parts of radish seed, 4 parts of perilla seed, 5 parts of pharbitis seed, 3 parts of costustoot, 4 parts of immature bitter orange, 1.5 parts of agilawood, 3 parts of liquorice, 5 parts of fried hawthorn, 4 parts of prepared rhubarb, 6 parts of fried malt, 7 parts of prepared cyperus rotundus, 6 parts of fried medicated leaven, 5 parts of ginger processed pinellia, 4 parts of poria cocos, 5 parts of coptis chinensis, 6 parts of black gardenia, 3 parts of gallnut, 5 parts of fingered citron and 3 parts of radix linderae.
Further, the present embodiment provides a preparation method of the traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin, including the following steps:
(1) preparing parched fructus crataegi, parched fructus Hordei Germinatus and parched Massa Medicata Fermentata
Cleaning fructus crataegi, air drying, parching at 70 deg.C below with strong fire for 30min, parching at 120 deg.C with strong fire for 10min, taking out, and cooling to obtain the parched fructus crataegi;
(2) preparing prepared rhubarb and prepared nutgrass galingale rhizome
Cleaning and airing rheum officinale, adding yellow wine for soaking for 2 hours, taking out the soaked rheum officinale, adding crystal sugar and water, and stir-frying for 30min at the temperature of 70 ℃ with a fire, wherein the mass ratio of the crystal sugar to the water to the rheum officinale is 1:1:4, so as to obtain the prepared rheum officinale;
(3) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water which accounts for 1/2 of the weight of each raw material respectively, mixing and grinding, adding malic acid which accounts for 1/5 of the weight of each raw material, acidifying for 7 hours, then adding yeast which accounts for 1/5 of the weight of each raw material respectively, and fermenting for 30 days at the fermentation temperature of 38 ℃ to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(4) respectively parching semen Pharbitidis, radix aucklandiae and fructus Aurantii Immaturus at 70 deg.C for 30min to obtain parched semen Pharbitidis, parched radix aucklandiae and parched fructus Aurantii Immaturus;
(5) mixing refined honey and boiling water at a mass ratio of 1:5 to dilute to obtain honey water, taking agilawood and liquorice according to the weight parts, respectively adding the honey water accounting for 1/3 of the mass of the raw materials to soak, airing, and stir-frying for 40min at 70 ℃ with fire to respectively obtain honey-fried agilawood and honey-fried liquorice;
(6) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing to particle size of 500 mesh, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; adding 1/5 mass of Mel into the mixture, and making into pill to obtain the Chinese medicinal composition with effects of resolving food stagnation, relaxing bowels and removing toxic substance.
Comparative example 1
The difference between the comparative example and the example 3 is only the difference of the raw material components, the comparative example does not contain the radish seed, the perilla seed, the pharbitis seed and the pharbitis seed, and the other operations are the same as the example 3.
Comparative example 2
The present comparative example is different from example 3 only in the preparation method, in which radish seed and perilla seed are separately decocted for 1-2 hours with 2 times mass of water to prepare decoctions, which are mixed with other raw materials in step (6); the pharbitis seed, the costustoot and the immature bitter orange are directly mixed and crushed in the step (6) without being fried, and other operations are the same as those in the example 3.
Examples of the experiments
Small intestine exercise experiment
Adult mice are selected and divided into four groups of example 3, example 5, comparative example 1 and comparative example 2, the traditional Chinese medicine compositions obtained in each group are respectively used for gastric lavage administration, the administration is finished after 20 days, fasting is not prohibited for 24 hours, compound diphenoxylate (0.025-0.05%) is administered in each experimental group, an indicator (ink and Arabic gum are used as indicators) is further administered in each group after 30 minutes, the neck is cut off and the animals are killed after 25 minutes, the ink propulsion ratio P is calculated (the calculation formula is shown in formula 1), the ink propulsion ratio P is high in value, the effect of the medicine for promoting the small intestine peristalsis is shown, and the specific result is shown in table 1.
TABLE 1 results of the intestinal motility experiment
| Index (I) | Example 3 | Example 5 | Comparative example 1 | Comparative example 2 |
| Ink push ratio P | 0.68 | 0.66 | 0.51 | 0.53 |
As can be seen from Table 1, the effect of the traditional Chinese medicine compositions obtained in the examples 3 and 5 of the invention on the mouse ink propulsion ratio P is obviously better than that of the traditional Chinese medicine compositions obtained in the comparative examples 1 and 2, which shows that the traditional Chinese medicine compositions obtained in the examples 3 and 5 have good effect of promoting gastrointestinal motility.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. A traditional Chinese medicine composition with effects of removing food retention, relaxing bowels and expelling toxin is characterized by comprising the following raw material components:
1-13 parts of radish seed, 2-15 parts of perilla seed, 2-10 parts of pharbitis seed, 1-8 parts of costustoot, 1-13 parts of immature bitter orange, 0.5-5.5 parts of agilawood, 1-8 parts of liquorice, 2-10 parts of fried hawthorn, 1-8 parts of prepared rhubarb, 1-10 parts of fried malt, 5-10 parts of prepared cyperus rotundus, 4-10 parts of fried medicated leaven, 2-15 parts of ginger processed pinellia, 2-15 parts of poria cocos, 3-10 parts of coptis chinensis, 2-10 parts of black gardenia, 1-13 parts of gallnut, 2-13 parts of fingered citron and 1-10 parts of combined spicebush root.
2. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to claim 1 is characterized by comprising the following raw material components:
2-5 parts of radish seed, 2-4 parts of perilla seed, 3-5 parts of pharbitis seed, 1-3 parts of costustoot, 2-4 parts of immature bitter orange, 0.5-1.5 parts of agilawood, 1-3 parts of liquorice, 2-5 parts of fried hawthorn, 1-4 parts of prepared rhubarb, 1-6 parts of fried malt, 5-7 parts of prepared cyperus rotundus, 4-6 parts of fried medicated leaven, 2-5 parts of ginger processed pinellia, 2-4 parts of poria cocos, 3-5 parts of coptis chinensis, 2-6 parts of black gardenia, 1-3 parts of gallnut, 2-5 parts of fingered citron and 1-3 parts of combined spicebush root.
3. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to claim 1 is characterized by comprising the following raw material components:
3 parts of radish seed, 3 parts of perilla seed, 4 parts of pharbitis seed, 2 parts of costustoot, 3 parts of immature bitter orange, 1 part of agilawood, 2 parts of liquorice, 3 parts of fried hawthorn, 2 parts of prepared rhubarb, 2 parts of fried malt, 6 parts of prepared nutgrass galingale rhizome, 5 parts of fried medicated leaven, 3 parts of ginger processed pinellia tuber, 3 parts of tuckahoe, 4 parts of coptis root, 3 parts of black gardenia, 2 parts of gallnut, 3 parts of fingered citron and 2 parts of radix linderae.
4. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to any one of claims 1 to 3, wherein the fried hawthorn is prepared by adopting the following method:
cleaning and drying the hawthorn, frying the hawthorn with slow fire, then frying the hawthorn with strong fire, taking out the hawthorn and cooling the hawthorn to obtain the fried hawthorn.
5. The traditional Chinese medicine composition with the effects of removing food stagnation, relaxing bowels and expelling toxin according to claim 4, wherein the stir-frying with slow fire is carried out for 10-30min, and the stir-frying with slow fire is carried out at the temperature of 50-70 ℃; the stir-frying time is 5-10min, and the stir-frying temperature is 90-120 ℃.
6. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to any one of claims 1 to 3, wherein the prepared rhubarb is prepared by adopting the following method:
cleaning radix et rhizoma Rhei, air drying, soaking in yellow wine, taking out the soaked radix et rhizoma Rhei, adding crystal sugar and water, and parching with slow fire to obtain the radix et rhizoma Rhei preparata.
7. The traditional Chinese medicine composition with effects of removing food stagnation, relaxing bowels and expelling toxin according to claim 6 is characterized in that the yellow wine is soaked for 1-2 hours, the rock candy, the water and the rhubarb are mixed according to a mass ratio of 1:1 (2-4), the slow fire frying temperature is 60-70 ℃, and the slow fire frying time is 20-30 min.
8. A method for preparing the traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to any one of claims 1 to 7, which is characterized by comprising the following steps:
(1) taking radish seed and perilla seed according to the weight parts, sequentially removing impurities, cleaning, drying and crushing respectively, adding water, mixing and grinding respectively, adding malic acid for acidification, and then adding yeast for fermentation respectively to obtain radish seed fermentation stock solution and perilla seed fermentation stock solution;
(2) respectively frying the pharbitis seed, the costustoot and the immature bitter orange in parts by weight with slow fire to obtain fried pharbitis seed, fried costus root and fried immature bitter orange;
(3) soaking agilawood and liquorice in honey water respectively according to the weight parts, airing, and frying with slow fire to obtain honey-fried agilawood and honey-fried liquorice respectively;
(4) mixing the fried semen Pharbitidis, fried radix aucklandiae, fried fructus Aurantii Immaturus, honey-fried lignum Aquilariae Resinatum, honey-fried Glycyrrhrizae radix, and the rest raw materials, pulverizing, adding Raphani semen fermentation stock solution and fructus Perillae fermentation stock solution, and stirring to obtain mixture; and adding honey into the mixture to prepare pills to obtain the traditional Chinese medicine composition with the effects of removing food stagnation, relaxing bowels and expelling toxin.
9. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to claim 8 is characterized in that in the step (1), the mass ratio of water to corresponding raw materials is 1 (1-2), the mass ratio of malic acid to corresponding raw materials is 1 (5-8), the acidification time is 6-7h, the mass ratio of yeast to corresponding raw materials is 1 (5-8), the fermentation temperature is 36-38 ℃, and the fermentation time is 20-30 days;
in the step (2), the stir-frying time is 10-30min, and the stir-frying temperature is 60-70 ℃.
10. The traditional Chinese medicine composition with the effects of removing food retention, relaxing bowels and expelling toxin according to claim 8 is characterized in that in the step (3), the honey water is a mixed system of refined honey and boiling water in a mass ratio of 1 (2-5), and the mass ratio of the agilawood or the liquorice to the honey water is (3-5) to 1; the stir-frying time is 30-40min, and the stir-frying temperature is 60-70 ℃;
in the step (4), the particle size after crushing is 200 meshes and 500 meshes, and the mass ratio of the honey to the mixture is 1 (5-7).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111298085A (en) * | 2020-03-30 | 2020-06-19 | 河南省伟仲和中医中药研究院有限公司 | Traditional Chinese medicine composition for benefiting qi, nourishing blood, clearing and activating channels and collaterals and preparation method thereof |
-
2019
- 2019-10-25 CN CN201911020811.7A patent/CN110613812A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 陈奇: "《中成药名方药理与临床》", 31 March 1998, 人民卫生出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111298085A (en) * | 2020-03-30 | 2020-06-19 | 河南省伟仲和中医中药研究院有限公司 | Traditional Chinese medicine composition for benefiting qi, nourishing blood, clearing and activating channels and collaterals and preparation method thereof |
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Application publication date: 20191227 |