CN110604770A - Cold granules - Google Patents

Cold granules Download PDF

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Publication number
CN110604770A
CN110604770A CN201911019495.1A CN201911019495A CN110604770A CN 110604770 A CN110604770 A CN 110604770A CN 201911019495 A CN201911019495 A CN 201911019495A CN 110604770 A CN110604770 A CN 110604770A
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China
Prior art keywords
cold
bottle body
parts
granules
storage box
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CN201911019495.1A
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Chinese (zh)
Inventor
冯桂侠
尹秀兰
林其昌
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Individual
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Individual
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Priority to CN201911019495.1A priority Critical patent/CN110604770A/en
Publication of CN110604770A publication Critical patent/CN110604770A/en
Priority to CN202010203930.2A priority patent/CN111249360A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015Devices specially adapted for taking medicines
    • A61J7/0046Cups, bottles or bags
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/40Heating or cooling means; Combinations thereof
    • A61J2200/42Heating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/70Device provided with specific sensor or indicating means
    • A61J2200/72Device provided with specific sensor or indicating means for temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, in particular to cold granules, which comprise a heating cup for preserving the granules; according to the invention, the traditional Chinese medicine components such as the wrinkled gianthyssop herb and the fineleaf schizonepeta herb are added in the cold medicinal granules, and the taking curative effect of the cold medicinal granules is enhanced by utilizing the effects of relieving summer-heat and summer-heat dampness exterior syndrome of the wrinkled gianthyssop herb and the effects of the fineleaf schizonepeta herb of relieving phlegm, dispelling wind, cooling blood, mainly treating influenza and headache and fever and sweating; in addition, the cold electuary is stored in the heating cup and taken by using the heating cup, so that the convenience of the electuary in taking is improved, the damage and the decomposition of the volatile oil with medicinal value can be effectively reduced, and the use curative effect of the cold electuary is effectively improved.

Description

Cold granules
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to cold granules.
Background
The common cold is caused by respiratory viruses, wherein the coronavirus and rhinovirus are main viruses, the clinical manifestations of the common cold are characterized by nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, fever, general malaise and the like, and the common cold can be caused all the year round, particularly in spring. Meanwhile, the cold is a self-healing disease, and the course of the disease is generally seven days, so the curative effect of the cold medicine is good or bad, and the effect taking speed is greatly reflected. The existing western medicines for treating cold are mostly symptomatic treatment, which can treat symptoms and root causes, have limited treatment effect, and have the side effects of lethargy, no semen collection, allergy and the like after taking the medicines, and the price of the western medicines is expensive. Many studies show that the traditional Chinese medicine has more advantages than western medicines in treating viral diseases (such as influenza A and atypical pneumonia).
When a patient travels or is in a severe cold environment, the cold electuary is difficult to take due to lack of warm water supply, intestines and stomach of the patient are often stimulated when the cold water is used for taking, the body temperature is reduced, and therefore the electuary cannot have a good treatment effect, the traditional cold electuary is usually stored in a medicine bag, the electuary needs to be poured into a cup after the cup is flatly placed and a packaging bag is torn when the cold water is used for taking, and the electuary in the packaging bag is often accidentally splashed when the cup is inconveniently placed flatly or the taking time is hasty, so that the convenience and the effectiveness of the cold electuary are greatly reduced when the cold electuary is taken; when the granule is taken with boiled water, the volatile oil components of the wrinkled giant hyssop, the asarum, the mint and the fineleaf schizonepeta herb in the granule are easy to volatilize and decompose by the boiled water with high temperature, thereby greatly reducing the treatment effect of the granule when the granule is taken.
In view of the above, the invention provides the cold granules which can effectively enhance the taking curative effect of the granules and can be reasonably stored and taken by the heating cup.
Disclosure of Invention
In order to make up for the defects of the prior art, the invention provides the cold electuary, which can effectively enhance the taking curative effect of the electuary and can be reasonably stored and taken by a heating cup.
The technical scheme adopted by the invention for solving the technical problems is as follows: the cold granules comprise the following main active components in parts by weight:
the cold granules are explained as follows:
bupleurum root: bitter in property and slightly cold in nature, entering liver and gallbladder meridians, harmonizing exterior and interior, soothing liver-qi stagnation, lifting yang and sinking, abating fever and checking malaria, and is commonly used for cold, fever, alternating chills and fever, etc.
Agastache rugosus: perennial herb, pungent and mild in flavor and meridian tropism, spleen, stomach and lung meridians, is mainly used for regulating the middle warmer and relieving vomiting, relieving summer-heat, treating summer-heat-dampness exterior syndrome, early damp-heat, fever and lassitude, chest distress and discomfort, cold-dampness retention and summer-heat, abdominal pain and vomiting and diarrhea, nasosinusitis and headache.
Honeysuckle flower: sweet and cold in nature and taste. It enters lung, heart and stomach meridians. Has effects of clearing away heat and toxic materials, and dispelling pathogenic wind and heat. Can be used for treating pharyngitis, erysipelas, dysentery with bloody stool due to toxic heat, common cold, epidemic febrile disease, and fever.
Kudzu root: sweet and pungent in property, even in spleen and stomach meridians, and can be used for treating typhoid fever, warm headache, promoting eruption, relieving diarrhea, relieving restlessness and relieving fever.
Licorice root: sweet and pungent in property, even in spleen and stomach meridians, and can be used for treating typhoid fever, warm headache, eruption, diarrhea, restlessness and warm-natured symptoms.
Houttuynia cordata: pungent taste and slightly cold nature; it enters lung, bladder and large intestine meridians. Has effects in clearing away heat and toxic materials, eliminating phlegm, expelling pus, resolving carbuncle, promoting urination, relieving swelling, and treating stranguria.
Purple perilla: pungent and warm taste; enter lung and spleen meridians. It can be used for treating wind-cold type common cold, headache, cough, and abdominal distention.
Asarum: pungent and warm, dispel wind and cold, unblock nasal orifices, and is mainly used for treating wind-cold headache, nasosinusitis, phlegm and fluid retention, cough, cold and nasal obstruction, and has antibacterial effect.
Mint: pungent taste and cool nature. Can be used for treating wind dispelling, heat clearing, toxic materials clearing away, wind-heat common cold, headache, sore throat, aphtha, early stage epidemic febrile disease, and rubella and pruritus.
Lumbricus, salty and cold in nature, enters liver, lung and bladder meridians, and can be used for vertigo, headache, cough and asthma due to lung heat, pyrolysis anuresis, hypertension, etc.
The astragalus root is sweet and warm, has the effects of tonifying qi, consolidating superficial resistance, promoting urination, detoxifying, expelling pus, healing sore and promoting granulation.
Preferably, the cold granules also comprise 10-15 parts of schizonepeta, and the schizonepeta is mild in taste, warm in nature, non-toxic and strong in fragrance; schizonepeta tenuifolia is a sweating and heat-clearing medicine, one of the common Chinese herbs, and has the effects of suppressing phlegm, dispelling wind and cooling blood. It can be used for treating influenza, headache, cold, fever, perspiration, and emesis.
Preferably, the preparation method of the cold granules comprises the following steps:
s1: weighing 4-10 parts of wrinkled gianthyssop herb, 5-10 parts of asarum, 15-25 parts of mint and 10-15 parts of schizonepeta according to weight parts, respectively extracting volatile oil by a redistillation method, and separating volatile oil layers for later use; the volatile oil with medicinal value in the components is fully extracted, and the generation of impurities is reduced;
s2: after a volatile oil layer is obtained in S1, homogenizing 10-16 parts of radix bupleuri, 20-40 parts of honeysuckle, 15-20 parts of radix puerariae, 10-15 parts of liquorice, 18-25 parts of houttuynia cordata, 2-8 parts of perilla, 6-12 parts of earthworm and 4-8 parts of astragalus membranaceus, adding 10 times of clear water to soak for 1 hour, decocting for 2 hours, and filtering to obtain a filtrate 1; adding 8 times of clear water into the decocted medicine residues, soaking for 1 hour, decocting for 1.5 hours, and filtering to obtain filtrate 2; mixing the filtrate 1 and the filtrate 2, and concentrating to obtain Chinese medicinal extract; so that the components with medicinal value in the medicinal materials are fully utilized;
s3: after S2, preparing a concentrated traditional Chinese medicine extract, uniformly mixing the volatile oil layers of the agastache rugosus, the asarum, the mint and the schizonepeta, then uniformly mixing the extract with the traditional Chinese medicine extract, adding gypsum and soluble starch, granulating, drying, sieving, subpackaging to obtain a product, and placing the product in a medicine storage box of a heating cup for storage and taking; on one hand, the convenience of the granule during taking is improved, and the volatilization and decomposition of volatile oil with medicinal value can be effectively reduced when the heating cup is used for taking the granule, so that the use curative effect of the granule is effectively improved.
Preferably, the heating cup in S3 includes a bottle body and a bottle cap, the bottle cap is mounted on the top end of the bottle body, a rotating plate is disposed inside the bottle body, the side surface of the rotating plate is in interference fit with the inner wall of the bottle body, the bottom end of the rotating plate is rotatably connected with the bottom surface inside the bottle body, and the rotating plate can rotate inside the bottle body under the action of external force; the side wall of the bottom end of the bottle body is provided with an electronic thermometer, the bottom surface of the bottle body is provided with a heating plate, the bottom of the heating plate is provided with a heating box, a lithium battery is arranged in the heating box, and the lithium battery is used for normal operation of the heating plate and the electronic thermometer; a water inlet groove is formed in one side of the inner wall of the bottle body, a medicine storage box is arranged on the side wall of the top end of the bottle body, a medicine inlet cover is arranged at the top of the medicine storage box, the inner end of the medicine storage box is communicated with the inside of the bottle body, a baffle is arranged at the communication position of the medicine storage box and the bottle body, the top end of the baffle is connected to the side wall of the bottle body through a torsion spring, and the baffle can seal the inside of; the outer surface of the bottle body is provided with a controller, and the controller controls the heating cup to automatically run; when the cold electuary is used, a cup needs to be flatly placed and a packaging bag needs to be torn off, and then the electuary is poured into the cup, when the cup is inconvenient to place flatly or the taking time is hasty, the electuary in the packaging bag is often accidentally splashed, so that the convenience and the effectiveness of the cold electuary in taking are greatly reduced; when the medicinal granules are taken with boiled water, volatile oil components of the agastache rugosus, the asarum, the mint and the schizonepeta are easy to volatilize and decompose in the medicinal granules by the boiled water with high temperature, so that the treatment effect of the medicinal granules is greatly reduced; when the heating cup is used, granules can be stored in the medicine storage box in advance at convenient time and place, the rotating plate in the original state divides the space inside the bottle body into two chambers, drinking water is poured into the chamber far away from the medicine storage box in advance, when the heating cup is used for taking medicine, the baffle at the inner end of the medicine storage box is firstly opened, the granules in the medicine storage box fall into the chamber of the bottle body close to one side of the medicine storage box by inclining the bottle body, the rotating plate rotates in the bottle body by applying acting force to the rotating plate, the drinking water far away from the chamber of the medicine storage box is driven to flow towards the water inlet groove when the rotating plate rotates, when the side edge of the rotating plate rotates to the position of the water inlet groove, the chambers at the two sides of the rotating plate are mutually communicated through the water inlet grooves, and the drinking water in the chamber at one side of the drinking water flows into the chamber at one side of the granules through, so that the electuary in the cavity is mixed with part of the drinking water, simultaneously, the edge of the rotating plate is rotated away from the water inlet groove by rotating the rotating plate again, and the cavities on the two sides of the rotating plate are isolated again, thereby playing the role of controlling the water quantity of the electuary; then the controller controls the heating plate to heat the liquid medicine in the bottle body, and the electronic thermometer monitors the temperature of the liquid medicine, so that volatilization and decomposition of components of volatile oil in the electuary caused by overhigh temperature in the bottle body are reduced, and the using curative effect of the electuary is effectively improved; the invention has the beneficial effects that: by storing the medicinal granules in the heating cup, the convenience of the medicinal granules in taking is improved, and the damage and decomposition of the volatile oil with medicinal value can be effectively reduced, so that the use curative effect of the medicinal granules for treating the cold is effectively improved.
Preferably, the bottom end of the baffle is in interference contact with the side face of the rotating plate when in a horizontal state, a limiting groove is formed in the side face of the rotating plate at the contact position of the two plates, and an elastic layer made of rubber materials is arranged at the bottom end of the baffle; when the rotary plate rotates under the action of uncontrollable external force, the rotating rotary plate easily enables the matched liquid medicine to be communicated with drinking water in a good proportion, and the matching proportion of the medicinal granules and the water is influenced, so that the medicine taking of a patient is influenced; and through when the liquid medicine heating, the artificial effort of exerting to the baffle bottom makes the elastic layer extrusion of baffle bottom advance the spacing groove, make the spacing groove can fix and support the baffle bottom that is located inside, the baffle bottom also exerts reverse holding power to the deflector lateral wall simultaneously, make the commentaries on classics board fix the position of self under the effect of baffle pressure, reduce the rotation that the commentaries on classics board takes place under uncontrollable exogenic action, thereby the effectual stability of heating the cup when taking the cold granules that has strengthened.
Preferably, the bottom end of the baffle is provided with a first magnet, the inner end of the bottom surface of the medicine storage box is provided with a second magnet, and the first magnet and the second magnet are opposite in magnetism; during operation, magnet and No. two magnet inter attraction for magnet drives the baffle bottom and closely laminates on the bottle lateral wall under the appeal effect of No. two magnet, thereby makes the baffle carry out more effective sealed and save to the inside granule of catching a cold of drug storage box, reduces the granule and receives the pollution of external impurity and bacterium, the effectual save quality and the effect of taking that improves the granule of catching a cold.
The invention has the following beneficial effects:
1. the invention enhances the curative effect of the cold granules by adding the traditional Chinese medicine components of the wrinkled gianthyssop herb, the fineleaf schizonepeta herb and the like in the cold granules and utilizing the effects of relieving summer-heat and dampness exterior syndrome of the wrinkled gianthyssop herb, and the fineleaf schizonepeta herb can suppress phlegm, dispel wind, cool blood and mainly treat influenza and headache and fever and sweating.
2. The cold electuary is stored in the heating cup and taken by using the heating cup, so that the convenience of the electuary in taking is improved, the damage and the decomposition of the volatile oil with medicinal value can be effectively reduced, and the use curative effect of the cold electuary is effectively improved.
Drawings
The invention will be further explained with reference to the drawings.
FIG. 1 is a diagram of the steps of the preparation method of the present invention;
FIG. 2 is a schematic perspective view of a heating cup of the present invention;
FIG. 3 is a schematic view of a heating cup according to the present invention;
FIG. 4 is an enlarged view at A in FIG. 3;
in the figure: bottle 1, intake channel 11, bottle lid 2, commentaries on classics board 3, spacing groove 31, electronic thermometer 4, hot plate 5, drug storage box 6, advance medicine lid 61, No. two magnet 62, baffle 7, elastic layer 71, magnet 72.
Detailed Description
In order to make the technical means, the creation features, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the following embodiments.
As shown in fig. 1-4, the cold granules of the present invention comprise the following main active components in parts by weight:
the cold granules are explained as follows:
bupleurum root: bitter in property and slightly cold in nature, entering liver and gallbladder meridians, harmonizing exterior and interior, soothing liver-qi stagnation, lifting yang and sinking, abating fever and checking malaria, and is commonly used for cold, fever, alternating chills and fever, etc.
Agastache rugosus: perennial herb, pungent and mild in flavor and meridian tropism, spleen, stomach and lung meridians, is mainly used for regulating the middle warmer and relieving vomiting, relieving summer-heat, treating summer-heat-dampness exterior syndrome, early damp-heat, fever and lassitude, chest distress and discomfort, cold-dampness retention and summer-heat, abdominal pain and vomiting and diarrhea, nasosinusitis and headache.
Honeysuckle flower: sweet and cold in nature and taste. It enters lung, heart and stomach meridians. Has effects of clearing away heat and toxic materials, and dispelling pathogenic wind and heat. Can be used for treating pharyngitis, erysipelas, dysentery with bloody stool due to toxic heat, common cold, epidemic febrile disease, and fever.
Kudzu root: sweet and pungent in property, even in spleen and stomach meridians, and can be used for treating typhoid fever, warm headache, promoting eruption, relieving diarrhea, relieving restlessness and relieving fever.
Licorice root: sweet and pungent in property, even in spleen and stomach meridians, and can be used for treating typhoid fever, warm headache, eruption, diarrhea, restlessness and warm-natured symptoms.
Houttuynia cordata: pungent taste and slightly cold nature; it enters lung, bladder and large intestine meridians. Has effects in clearing away heat and toxic materials, eliminating phlegm, expelling pus, resolving carbuncle, promoting urination, relieving swelling, and treating stranguria.
Purple perilla: pungent and warm taste; enter lung and spleen meridians. It can be used for treating wind-cold type common cold, headache, cough, and abdominal distention.
Asarum: pungent and warm, dispel wind and cold, unblock nasal orifices, and is mainly used for treating wind-cold headache, nasosinusitis, phlegm and fluid retention, cough, cold and nasal obstruction, and has antibacterial effect.
Mint: pungent taste and cool nature. Can be used for treating wind dispelling, heat clearing, toxic materials clearing away, wind-heat common cold, headache, sore throat, aphtha, early stage epidemic febrile disease, and rubella and pruritus.
Lumbricus, salty and cold in nature, enters liver, lung and bladder meridians, and can be used for vertigo, headache, cough and asthma due to lung heat, pyrolysis anuresis, hypertension, etc.
The astragalus root is sweet and warm, has the effects of tonifying qi, consolidating superficial resistance, promoting urination, detoxifying, expelling pus, healing sore and promoting granulation.
As an embodiment of the invention, the cold granules also comprise 10-15 parts of schizonepeta, and the schizonepeta has the advantages of mild taste, warm nature, no toxicity and strong fragrance; schizonepeta tenuifolia is a sweating and heat-clearing medicine, one of the common Chinese herbs, and has the effects of suppressing phlegm, dispelling wind and cooling blood. It can be used for treating influenza, headache, cold, fever, perspiration, and emesis.
As an embodiment of the present invention, the method for preparing the cold granules comprises:
s1: weighing 4-10 parts of wrinkled gianthyssop herb, 5-10 parts of asarum, 15-25 parts of mint and 10-15 parts of schizonepeta according to weight parts, respectively extracting volatile oil by a redistillation method, and separating volatile oil layers for later use; the volatile oil with medicinal value in the components is fully extracted, and the generation of impurities is reduced;
s2: after a volatile oil layer is obtained in S1, homogenizing 10-16 parts of radix bupleuri, 20-40 parts of honeysuckle, 15-20 parts of radix puerariae, 10-15 parts of liquorice, 18-25 parts of houttuynia cordata, 2-8 parts of perilla, 6-12 parts of earthworm and 4-8 parts of astragalus membranaceus, adding 10 times of clear water to soak for 1 hour, decocting for 2 hours, and filtering to obtain a filtrate 1; adding 8 times of clear water into the decocted medicine residues, soaking for 1 hour, decocting for 1.5 hours, and filtering to obtain filtrate 2; mixing the filtrate 1 and the filtrate 2, and concentrating to obtain Chinese medicinal extract; so that the components with medicinal value in the medicinal materials are fully utilized;
s3: after S2, preparing a concentrated traditional Chinese medicine extract, uniformly mixing the volatile oil layers of the agastache rugosus, the asarum, the mint and the schizonepeta, then uniformly mixing the extract with the traditional Chinese medicine extract, adding gypsum and soluble starch, granulating, drying, sieving, subpackaging to obtain a product, and placing the product in a medicine storage box of a heating cup for storage and taking; on one hand, the convenience of the granule during taking is improved, and the volatilization and decomposition of volatile oil with medicinal value can be effectively reduced when the heating cup is used for taking the granule, so that the use curative effect of the granule is effectively improved.
As an embodiment of the present invention, the heating cup in S3 includes a bottle body 1 and a bottle cap 2, the bottle cap 2 is installed at the top end of the bottle body 1, a rotating plate 3 is installed inside the bottle body 1, the side surface of the rotating plate 3 is installed in interference with the inner wall of the bottle body 1, the bottom end of the rotating plate 3 is rotatably connected to the bottom surface inside the bottle body 1, and the rotating plate 3 can rotate inside the bottle body 1 under the action of an external force; an electronic thermometer 4 is arranged on the side wall of the bottom end of the bottle body 1, a heating plate 5 is arranged on the bottom surface of the bottle body 1, a heating box is arranged at the bottom of the heating plate 5, a lithium battery is arranged in the heating box, and the lithium battery is used for normal operation of the heating plate 5 and the electronic thermometer 4; a water inlet groove 11 is formed in one side of the inner wall of the bottle body 1, a medicine storage box 6 is arranged on the side wall of the top end of the bottle body 1, a medicine inlet cover 61 is arranged at the top of the medicine storage box 6, the inner end of the medicine storage box 6 is communicated with the inside of the bottle body 1, a baffle 7 is arranged at the communication position of the medicine storage box 6 and the bottle body 1, the top end of the baffle 7 is connected to the side wall of the bottle body 1 through a torsion spring, and the baffle 7 can seal the inside of the; the outer surface of the bottle body 1 is provided with a controller, and the controller controls the heating cup to automatically run; when the cold electuary is used, a cup needs to be flatly placed and a packaging bag needs to be torn off, and then the electuary is poured into the cup, when the cup is inconvenient to place flatly or the taking time is hasty, the electuary in the packaging bag is often accidentally splashed, so that the convenience and the effectiveness of the cold electuary in taking are greatly reduced; when the medicinal granules are taken with boiled water, volatile oil components of the agastache rugosus, the asarum, the mint and the schizonepeta are easy to volatilize and decompose in the medicinal granules by the boiled water with high temperature, so that the treatment effect of the medicinal granules is greatly reduced; when the heating cup is used, granules can be stored in the medicine storage box 6 in advance at convenient time and place, the rotating plate 3 in the original state divides the space inside the bottle body 1 into two chambers, drinking water is poured into the chamber far away from the medicine storage box 6 in the bottle body 1 in advance, when the heating cup is used for taking medicine, the baffle 7 at the inner end of the medicine storage box 6 is firstly opened, the granules in the medicine storage box 6 fall into the chamber of the bottle body 1 near one side of the medicine storage box by inclining the bottle body 1, the rotating plate 3 rotates in the bottle body 1 by applying acting force on the rotating plate 3, the drinking water far away from the chamber of the medicine storage box 6 is driven to flow towards the water inlet groove 11 when the rotating plate 3 rotates to the position of the water inlet groove 11, the chambers at two sides of the rotating plate 3 are mutually communicated through the water inlet groove 11, the drinking water in the chamber at one side flows into the chamber at one side of the granules through the water inlet groove 11, so that the electuary in the cavity is mixed with part of drinking water, meanwhile, the edge of the rotating plate 3 is rotated away from the water inlet groove 11 by rotating the rotating plate 3 again, and the cavities on the two sides of the rotating plate 3 are isolated again, thereby playing the role of controlling the water quantity of the electuary; then the controller controls the heating plate 5 to heat the liquid medicine in the bottle body 1, and the electronic thermometer 4 monitors the temperature of the liquid medicine, so that volatilization and decomposition of volatile oil components in the medicinal granules caused by overhigh temperature in the bottle body 1 are reduced, and the using curative effect of the medicinal granules is effectively improved; the invention has the beneficial effects that: by storing the medicinal granules in the heating cup, the convenience of the medicinal granules in taking is improved, and the damage and decomposition of the volatile oil with medicinal value can be effectively reduced, so that the use curative effect of the medicinal granules for treating the cold is effectively improved.
As an embodiment of the present invention, the bottom end of the baffle 7 is in interference contact with the side surface of the rotating plate 3 when in a horizontal state, the side surface of the rotating plate 3 where the two plates are in contact is provided with a limiting groove 31, and the bottom end of the baffle 7 is provided with an elastic layer 71 made of a rubber material; when the rotary plate 3 rotates under the action of an uncontrollable external force during working, the rotary plate 3 can easily ensure that the matched liquid medicine and the drinking water are communicated in a proper proportion, and the matching proportion of the medicinal granules and the water is influenced, so that the medicine taking of a patient is influenced; and through when the liquid medicine heats, the artificial effort of exerting to baffle 7 bottom makes the elastic layer 71 extrusion of baffle 7 bottom advance spacing groove 31, make spacing groove 31 can fix and support the baffle 7 bottom that is located inside, reverse holding power is also exerted to 3 lateral walls of deflector to the baffle 7 bottom simultaneously, make deflector 3 fix the position of self under the effect of baffle 7 pressure, reduce the rotation that deflector 3 takes place under uncontrollable exogenic action, thereby the effectual stability of heating cup when taking the cold granules that has strengthened.
As an embodiment of the present invention, a first magnet 72 is disposed at the bottom end of the baffle 7, a second magnet 62 is disposed at the inner end of the bottom surface of the medicine storage box 6, and the first magnet 72 and the second magnet 62 have opposite magnetism; during operation, magnet 72 and No. two magnet 62 inter attraction for magnet 72 drives baffle 7 bottom under No. two magnet 62's appeal effect and closely laminates on the lateral wall of bottle 1, thereby makes baffle 7 carry out more effective sealed and save to the inside granule that catches a cold of drug storage box 6, reduces the granule and receives the pollution of external impurity and bacterium, the effectual storage quality and the effect of taking that improves the granule that catches a cold.
To verify the effect of the addition of Agastache rugosa and Schizonepeta tenuifolia according to the present invention, the following tests of examples 1-3 were carried out by the person skilled in the art.
Example 1
Weighing 4 g of wrinkled gianthyssop herb, 10 g of fineleaf schizonepeta herb, 5 g of manchurian wildginger and 15 g of mint according to the weight, respectively extracting volatile oil by a redistillation method, dividing volatile oil layers for later use, homogenizing dregs of medicinal herbs of 10 g of Chinese thorowax root, 20 g of honeysuckle flower, 15 g of kudzuvine root, 10 g of liquoric root, 18 g of heartleaf houttuynia herb, 2 g of perilla frutescens, 6 g of earthworm and 4 g of astragalus root, adding 10 times of clear water for soaking for 1 hour, decocting for 2 hours; adding 8 times of clear water into the decocted medicine residues, soaking for 1 hour, decocting for 1.5 hours, and filtering to obtain filtrate 2; mixing the filtrate 1 and the filtrate 2, concentrating into a traditional Chinese medicine extract, uniformly mixing the standby volatile oil layers, uniformly mixing with the traditional Chinese medicine extract, adding gypsum and soluble starch, granulating, drying, sieving and subpackaging to obtain cold granules, placing the product in a medicine storage box of a heating cup, extracting 100 volunteers with similar cold degree, half male and female, and the age of 20-40 years, treating 100 cold patients by taking the same amount of cold granules once in the morning and at night, and counting the condition improvement condition of the volunteers after one week.
Example 2
Weighing 8 g of wrinkled gianthyssop herb, 10 g of fineleaf schizonepeta herb, 5 g of manchurian wildginger and 15 g of mint according to the weight, respectively extracting volatile oil by a redistillation method, dividing volatile oil layers for later use, homogenizing dregs of medicinal herbs of 10 g of Chinese thorowax root, 20 g of honeysuckle flower, 15 g of kudzuvine root, 10 g of liquoric root, 18 g of heartleaf houttuynia herb, 2 g of perilla frutescens, 6 g of earthworm and 4 g of astragalus root, adding 10 times of clear water for soaking for 1 hour, decocting for 2 hours; adding 8 times of clear water into the decocted medicine residues, soaking for 1 hour, decocting for 1.5 hours, and filtering to obtain filtrate 2; mixing the filtrate 1 and the filtrate 2, concentrating into a traditional Chinese medicine extract, uniformly mixing the standby volatile oil layers, uniformly mixing with the traditional Chinese medicine extract, adding gypsum and soluble starch, granulating, drying, sieving and subpackaging to obtain cold granules, placing the product in a medicine storage box of a heating cup, extracting 100 volunteers with similar cold degree, half male and female, and the age of 20-40 years, treating 100 cold patients by taking the same amount of cold granules once in the morning and at night, and counting the condition improvement condition of the volunteers after one week.
Example 3
Weighing 4 g of wrinkled gianthyssop herb, 15 g of fineleaf schizonepeta herb, 5 g of manchurian wildginger and 15 g of mint according to the weight, respectively extracting volatile oil by a redistillation method, dividing volatile oil layers for later use, homogenizing dregs of medicinal herbs of 10 g of Chinese thorowax root, 20 g of honeysuckle flower, 15 g of kudzuvine root, 10 g of liquoric root, 18 g of heartleaf houttuynia herb, 2 g of perilla frutescens, 6 g of earthworm and 4 g of astragalus root, adding 10 times of clear water for soaking for 1 hour, decocting for 2 hours; adding 8 times of clear water into the decocted medicine residues, soaking for 1 hour, decocting for 1.5 hours, and filtering to obtain filtrate 2; mixing the filtrate 1 and the filtrate 2, concentrating into a traditional Chinese medicine extract, uniformly mixing the standby volatile oil layers, uniformly mixing with the traditional Chinese medicine extract, adding gypsum and soluble starch, granulating, drying, sieving and subpackaging to obtain cold granules, placing the product in a medicine storage box of a heating cup, extracting 100 volunteers with similar cold degree, half male and female, and the age of 20-40 years, treating 100 cold patients by taking the same amount of cold granules once in the morning and at night, and counting the condition improvement condition of the volunteers after one week.
The statistical results of examples 1 to 3 are shown in table one.
Table one
The table I shows that the addition of the wrinkled gianthyssop herb and the fineleaf schizonepeta herb to the components of the cold medicinal granules can effectively improve the taking curative effect of the cold medicinal granules, and the curative effect of the cold medicinal granules is enhanced along with the increase of the components of the wrinkled gianthyssop herb and the fineleaf schizonepeta herb under the condition of ensuring that other components are unchanged.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are given by way of illustration of the principles of the present invention, and that various changes and modifications may be made without departing from the spirit and scope of the invention as defined by the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (6)

1. The cold granules are characterized in that: the cold granules comprise the following main active components in parts by weight:
2. the cold granule according to claim 1, wherein: also comprises 10-15 parts of schizonepeta, and the schizonepeta has mild taste, warm property, no toxicity and strong fragrance.
3. The granule for treating cold according to claim 2, wherein: the preparation method of the cold granules comprises the following steps:
s1: weighing 4-10 parts of wrinkled gianthyssop herb, 5-10 parts of asarum, 15-25 parts of mint and 10-15 parts of schizonepeta according to weight parts, respectively extracting volatile oil by a redistillation method, and separating volatile oil layers for later use;
s2: after a volatile oil layer is obtained in S1, homogenizing 10-16 parts of radix bupleuri, 20-40 parts of honeysuckle, 15-20 parts of radix puerariae, 10-15 parts of liquorice, 18-25 parts of houttuynia cordata, 2-8 parts of perilla, 6-12 parts of earthworm and 4-8 parts of astragalus membranaceus, adding 10 times of clear water to soak for 1 hour, decocting for 2 hours, and filtering to obtain a filtrate 1; adding 8 times of clear water into the decocted medicine residues, soaking for 1 hour, decocting for 1.5 hours, and filtering to obtain filtrate 2; mixing the filtrate 1 and the filtrate 2, and concentrating to obtain Chinese medicinal extract;
s3: after the concentrated traditional Chinese medicine extract is prepared in S2, the agastache rugosus, the asarum, the mint and the volatile oil layer of the schizonepeta are uniformly mixed, then the mixture is uniformly mixed with the traditional Chinese medicine extract, gypsum and soluble starch are added, and the mixture is granulated, dried, sieved and subpackaged to obtain a product, and the product is placed in a medicine storage box of a heating cup for storage and taking.
4. The granule for treating cold according to claim 3, wherein: the heating cup in the S3 comprises a bottle body (1) and a bottle cap (2), wherein the bottle cap (2) is installed at the top end of the bottle body (1), a rotating plate (3) is arranged inside the bottle body (1), the side face of the rotating plate (3) is installed on the inner wall of the bottle body (1) in an interference mode, the bottom end of the rotating plate (3) is rotatably connected with the bottom face inside the bottle body (1), and the rotating plate (3) can rotate in the bottle body (1) under the action of external force; an electronic thermometer (4) is arranged on the side wall of the bottom end of the bottle body (1), a heating plate (5) is arranged on the bottom surface of the bottle body (1), a heating box is arranged at the bottom of the heating plate (5), a lithium battery is arranged in the heating box, and the lithium battery is used for normal operation of the heating plate (5) and the electronic thermometer (4); a water inlet groove (11) is formed in one side of the inner wall of the bottle body (1), a medicine storage box (6) is arranged on the side wall of the top end of the bottle body (1), a medicine inlet cover (61) is arranged at the top of the medicine storage box (6), the inner end of the medicine storage box (6) is communicated with the inside of the bottle body (1), a baffle (7) is arranged at the communication position of the medicine storage box (6) and the bottle body (1), the top end of the baffle (7) is connected to the side wall of the bottle body (1) through a torsion spring, and the baffle (7) can seal the inside of the medicine storage box; the outer surface of the bottle body (1) is provided with a controller which controls the automatic operation of the heating cup.
5. The granule for treating cold according to claim 4, wherein: when being in a horizontal state, the bottom end of the baffle (7) is in interference contact with the side face of the rotating plate (3), a limiting groove (31) is formed in the side face of the rotating plate (3) at the contact position of the two plates, and an elastic layer (71) made of rubber materials is arranged at the bottom end of the baffle (7).
6. The granule for treating cold according to claim 5, wherein: the bottom end of the baffle (7) is provided with a first magnet (72), the inner end of the bottom surface of the medicine storage box (6) is provided with a second magnet (62), and the first magnet (72) and the second magnet (62) are opposite in magnetism.
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Application publication date: 20191224