CN110585049A - Sulforaphane sun cream - Google Patents

Sulforaphane sun cream Download PDF

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Publication number
CN110585049A
CN110585049A CN201911005279.1A CN201911005279A CN110585049A CN 110585049 A CN110585049 A CN 110585049A CN 201911005279 A CN201911005279 A CN 201911005279A CN 110585049 A CN110585049 A CN 110585049A
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CN
China
Prior art keywords
parts
sulforaphane
raw materials
extract
ultraviolet rays
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911005279.1A
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Chinese (zh)
Inventor
刘儒华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hua Han Bio Tech Ltd Ganzhou
Original Assignee
Hua Han Bio Tech Ltd Ganzhou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hua Han Bio Tech Ltd Ganzhou filed Critical Hua Han Bio Tech Ltd Ganzhou
Priority to CN201911005279.1A priority Critical patent/CN110585049A/en
Publication of CN110585049A publication Critical patent/CN110585049A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses sulforaphane sun cream which is prepared from the following raw materials in parts by weight: stearic acid 3-9 parts, SiO23-11 parts of solid particles, 2-4 parts of glutathione, 2-4 parts of hexadecanol, 5-10 parts of isopropyl palmitate, 2-6 parts of glycerol, 2-4 parts of olive oil, 2-5 parts of phenoxyethanol, 4-12 parts of titanium dioxide, 8-16 parts of zinc oxide, 1-3 parts of sulforaphane and 40-60 parts of deionized water. The raw materials without irritation, preservative and sensitization components are selected to effectively block and absorb ultraviolet rays in sunlight, and the sulforaphane component is added into the sunscreen cream for use, so that the sulforaphane can effectively prevent and inhibit radiation damage of ultraviolet rays to a human body, and can also perform anti-inflammation and sterilization effects on sunburned skin; on the other hand, the cost is lower, the resources are fully utilized, and the utilization value of the sulforaphane is expanded.

Description

Sulforaphane sun cream
Technical Field
The invention relates to the technical field of daily chemical products, in particular to sulforaphane sun cream.
Background
Ultraviolet (UV) rays in sunlight are a completely carcinogenic substance, and short-term concentrated or long-term intermittent ultraviolet radiation can cause skin damage, and especially, medium-wave Ultraviolet (UVB) rays in sunlight are closely related to various skin diseases including photoaging, skin inflammation and skin cancer. Therefore, it is important to protect the skin from sunlight.
With the enhancement of people's knowledge of ultraviolet radiation, more and more people can shield or absorb ultraviolet rays in sunlight by applying cosmetics containing sunscreen agents, and avoid damage of excessive radiation to human bodies. However, most of the current sunscreen agents have common sunscreen effect and short duration, and need frequent supplementary painting, so the application is not very convenient.
Sulforaphane is a type of isothiocyanate with the strongest anticancer activity found in vegetables so far, is one of the natural products with the best anticancer and cancer prevention effects recognized at present, has obvious blocking effect on cancer, is an inducer with the strongest capacity of inducing II-type detoxification enzymes in the nature, and also has pharmacological effects of protecting skin, resisting bacteria, improving the oxidation resistance and the immunity of organisms and the like. Sulforaphane is mainly prepared from glucosinolates in roots, stems, leaves and seeds of Brassica vegetables of Brassicaceae such as broccoli, cauliflower, caulis et folium Brassicae Capitatae, radix Raphani, and caulis et folium Brassicae Junceae by enzymolysis or hydrolysis. In recent years, the sulforaphane has a strong photoprotection effect, can effectively inhibit radiation damage of UVB to a human body, and can effectively inhibit acute skin inflammatory reaction caused by ultraviolet rays. Therefore, the sulforaphane, an effective active ingredient, is added into the sunscreen cream to effectively improve the sunscreen effect and inhibit skin injury and inflammation.
Disclosure of Invention
The invention aims to overcome the technical defects and provide the sulforaphane sunscreen cream which has a good sunscreen effect and can effectively inhibit skin inflammation.
In order to achieve the purpose of the invention, the invention adopts the technical scheme that: the sulforaphane sun cream is prepared from the following raw materials in parts by weight: stearic acid 3-9 parts, SiO23-11 parts of solid particles, 2-4 parts of glutathione, 2-4 parts of hexadecanol, 5-10 parts of isopropyl palmitate, 2-6 parts of glycerol, 2-4 parts of olive oil, 2-5 parts of phenoxyethanol, 4-12 parts of titanium dioxide, 8-16 parts of zinc oxide, 1-3 parts of sulforaphane and 40-60 parts of deionized water.
Further, the sulforaphane is an extract from broccoli or broccoli seeds.
Further, the method for extracting the sulforaphane comprises an ethanol extract, an ethyl acetate extract and a dichloromethane extract.
Further, the purity of the sulforaphane is 0.01-80%.
The invention has the beneficial effects that: the raw materials without irritation, preservative and sensitization components are selected to effectively block and absorb ultraviolet rays in sunlight, and the sulforaphane component is added into the sunscreen cream for use, so that the sulforaphane can effectively prevent and inhibit radiation damage of ultraviolet rays to a human body, and can also perform anti-inflammation and sterilization effects on sunburned skin; on the other hand, the cost is lower, the resources are fully utilized, and the utilization value of the sulforaphane is expanded.
Detailed Description
In order to make the content of the present invention more clearly understood, the technical solutions in the embodiments of the present invention are clearly and completely described below.
The composition of the invention is suitable for daily care of facial skin. Of course, other areas of the neck, torso, hands, arms, legs, etc. may be used to improve skin condition.
Example one
The sulforaphane sun cream is prepared from the following raw materials in parts by weight: stearic acid 3 parts, SiO23 parts of solid particles, 2 parts of glutathione, 2 parts of cetyl alcohol, 5 parts of isopropyl palmitate, 2 parts of glycerol, 2 parts of olive oil, 2 parts of phenoxyethanol, 4 parts of titanium dioxide, 8 parts of zinc oxide, 1 part of sulforaphane and 40 parts of deionized water; the sulforaphane is an extract from broccoli or broccoli seeds; the method for extracting the sulforaphane comprises the steps of extracting by using ethanol, extracting by using ethyl acetate and extracting by using dichloromethane; the sulforaphane has a purity of 0.01%.
Example two
The sulforaphane sun cream is prepared from the following raw materials in parts by weight: stearic acid 6 parts, SiO27 parts of solid particles, 3 parts of glutathione, 3 parts of hexadecanol, 8 parts of isopropyl palmitate, 4 parts of glycerol, 3 parts of olive oil, 4 parts of phenoxyethanol, 8 parts of titanium dioxide, 12 parts of zinc oxide, 2 parts of sulforaphane and 50 parts of deionized water; the sulforaphane is an extract from broccoli or broccoli seeds; the method for extracting the sulforaphane comprises the steps of extracting by using ethanol, extracting by using ethyl acetate and extracting by using dichloromethane; the sulforaphane has a purity of 40%。
EXAMPLE III
The sulforaphane sun cream is prepared from the following raw materials in parts by weight: 9 parts of stearic acid, SiO211 parts of solid particles, 4 parts of glutathione, 4 parts of hexadecanol, 10 parts of isopropyl palmitate, 6 parts of glycerol, 4 parts of olive oil, 5 parts of phenoxyethanol, 12 parts of titanium dioxide, 16 parts of zinc oxide, 3 parts of sulforaphane and 60 parts of deionized water; the sulforaphane is an extract from broccoli or broccoli seeds; the method for extracting the sulforaphane comprises the steps of extracting by using ethanol, extracting by using ethyl acetate and extracting by using dichloromethane; the sulforaphane has a purity of 80%.
The present invention and the embodiments thereof have been described above, but the description is not limited to the embodiments, but only one of the embodiments of the present invention, and the actual embodiments are not limited thereto. In conclusion, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (4)

1. The sulforaphane sun cream is characterized by being prepared from the following raw materials in parts by weight: stearic acid 3-9 parts, SiO23-11 parts of solid particles, 2-4 parts of glutathione, 2-4 parts of hexadecanol, 5-10 parts of isopropyl palmitate, 2-6 parts of glycerol, 2-4 parts of olive oil, 2-5 parts of phenoxyethanol, 4-12 parts of titanium dioxide, 8-16 parts of zinc oxide, 1-3 parts of sulforaphane and 40-60 parts of deionized water.
2. The sulforaphane sunscreen cream according to claim 1, characterized in that: the sulforaphane is an extract from broccoli or broccoli seeds.
3. The sulforaphane sunscreen cream according to claim 1, characterized in that: the method for extracting the sulforaphane comprises an ethanol extract, an ethyl acetate extract and a dichloromethane extract.
4. The sulforaphane sunscreen cream according to claim 1, characterized in that: the sulforaphane has the purity of 0.01-80%.
CN201911005279.1A 2019-10-22 2019-10-22 Sulforaphane sun cream Pending CN110585049A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911005279.1A CN110585049A (en) 2019-10-22 2019-10-22 Sulforaphane sun cream

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911005279.1A CN110585049A (en) 2019-10-22 2019-10-22 Sulforaphane sun cream

Publications (1)

Publication Number Publication Date
CN110585049A true CN110585049A (en) 2019-12-20

Family

ID=68849928

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911005279.1A Pending CN110585049A (en) 2019-10-22 2019-10-22 Sulforaphane sun cream

Country Status (1)

Country Link
CN (1) CN110585049A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101208079A (en) * 2005-04-29 2008-06-25 约翰斯霍普金斯大学 Methods of suppressing UV light-induced skin carcinogenesis
CN104042469A (en) * 2014-05-31 2014-09-17 青岛博泓海洋生物技术有限公司 Sun cream containing natural plants
CN105708752A (en) * 2016-01-25 2016-06-29 夏继英 Sunscreen cream
CN105997747A (en) * 2016-07-19 2016-10-12 广西驰胜农业科技有限公司 Sun cream for sensitive skin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101208079A (en) * 2005-04-29 2008-06-25 约翰斯霍普金斯大学 Methods of suppressing UV light-induced skin carcinogenesis
CN104042469A (en) * 2014-05-31 2014-09-17 青岛博泓海洋生物技术有限公司 Sun cream containing natural plants
CN105708752A (en) * 2016-01-25 2016-06-29 夏继英 Sunscreen cream
CN105997747A (en) * 2016-07-19 2016-10-12 广西驰胜农业科技有限公司 Sun cream for sensitive skin

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
人民军医出版社: "《医学疑难问题解答》", 31 December 1984, 解放军出版社 *
吴映蓉: "《吃对五色蔬果 营养学博士教你认识植物营养素》", 31 August 2011, 生活•读书•新知三联书店 *
国家食品药品监督管理局总局: "《化妆品安全技术规范2015年版》", 1 December 2016 *
宋晓秋: "《普通高等教育"十三五"规划教材 化妆品原料学》", 31 July 2018, 中国轻工业出版社 *
董华模: "《化学物的毒性及其环境保护参数手册》", 31 May 1988, 人民卫生出版社 *
阳晖等: "《食品工艺学实验》", 31 May 2019, 西南交通大学出版社 *

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