CN110539905A - Automatic liquid split-charging mechanism and working method thereof - Google Patents

Abstract

The invention relates to a liquid automatic split charging mechanism and a working method thereof, wherein the mechanism comprises a fixed frame, a liquid pumping structure and a liquid separating structure, the liquid pumping structure and the liquid separating structure are respectively connected to the fixed frame, the liquid separating structure comprises a tray for placing a freezing storage pipe and a liquid storage tank and a tray moving assembly for driving the tray to move, and the liquid pumping structure is positioned above the tray; when liquid split charging is needed, the tray moving assembly works to drive the tray to move, so that the liquid storage tank is located below the liquid pumping structure, after the liquid storage tank is pumped by the liquid pumping structure, the tray moving assembly works to drive the tray to move, so that the freezing pipe is located below the liquid pumping structure, and liquid is pumped out to the freezing pipe through the liquid pumping structure. The invention realizes automatic liquid subpackaging into the freezing storage tube, improves the liquid subpackaging efficiency and further improves the cell preparation efficiency.

Description

Automatic liquid split-charging mechanism and working method thereof

Technical Field

The invention relates to a liquid split charging mechanism, in particular to an automatic liquid split charging mechanism and a working method thereof.

Background

In the process of cell preparation, need carry out the partial shipment with the culture solution to accomplish the partial shipment culture of cell, the partial shipment mode that adopts at present carries out the partial shipment by the manual work, specifically uses electronic aspirator and a plurality of cryopreserving pipe to carry out the partial shipment, and this partial shipment method is consuming time and power more, and although the type of partial shipment device on the market is more, nevertheless does not appear can be used for the partial shipment device of cryopreserving pipe partial shipment liquid yet.

therefore, it is necessary to design a new mechanism for automatically dispensing liquid into the cryopreservation tube, thereby improving the liquid dispensing efficiency and further improving the cell preparation efficiency.

Disclosure of Invention

the invention aims to overcome the defects of the prior art and provides an automatic liquid split charging mechanism and a working method thereof.

In order to achieve the purpose, the invention adopts the following technical scheme: the automatic liquid split charging mechanism comprises a fixed frame, a liquid pumping structure and a liquid separating structure, wherein the liquid pumping structure and the liquid separating structure are respectively connected to the fixed frame, the liquid separating structure comprises a tray for placing a freezing pipe and a liquid storage tank and a tray moving assembly for driving the tray to move, and the liquid pumping structure is positioned above the tray; when liquid needs to be subpackaged, the tray moving assembly works to drive the tray to move so that the liquid storage tank is located below the liquid pumping structure, after the liquid storage tank is pumped by the liquid pumping structure, the tray moving assembly works to drive the tray to move so that the freezing storage pipe is located below the liquid pumping structure, and liquid is pumped out to the freezing storage pipe by the liquid pumping structure.

The further technical scheme is as follows: the pump liquid structure is including annotating the liquid head, annotating the liquid power supply, annotating the liquid mounting panel and annotating liquid removal subassembly, annotate the liquid removal subassembly connect in on the mount, annotate the liquid power supply and annotate the liquid head connect respectively in annotate on the liquid mounting panel, just annotate the liquid mounting panel with it connects to annotate the liquid removal subassembly.

The further technical scheme is as follows: annotate the liquid mounting panel including the vertical linkage segment of first vertical linkage segment, horizontal connection section and the vertical linkage segment of second that connects gradually, first vertical linkage segment with annotate the liquid and remove the subassembly and connect, annotate the liquid head and annotate the liquid power supply connect with on the vertical linkage segment of second.

The further technical scheme is as follows: the lower end of the liquid injection head extends to the lower part of the second vertical connecting section.

The further technical scheme is as follows: annotate liquid removal subassembly including annotating liquid servo module, annotate liquid servo module through annotating liquid installing support with the mount is connected, first vertical linkage segment connect in annotate on the liquid servo module.

The further technical scheme is as follows: the tray is provided with a plurality of jacks and a tank body support, the tray moving assembly is connected with a tray mounting plate, and the tray is connected with the tray mounting plate.

The further technical scheme is as follows: the tray moving assembly comprises an X-axis servo module and a Y-axis servo module, the X-axis servo module is connected to the fixing frame, and the Y-axis servo module is connected to the X-axis servo module.

The further technical scheme is as follows: the X-axis servo module is connected with the fixing frame through an X-axis connecting seat.

The further technical scheme is as follows: the Y-axis servo module is connected to the X-axis servo module through a Y-axis connecting seat

The invention also provides a working method of the automatic liquid split charging mechanism, which comprises the following steps:

When liquid split charging is needed, the tray moving assembly works to drive the tray to move, so that the liquid storage tank is located below the liquid pumping structure, the liquid pumping structure pumps the liquid storage tank and then returns to an initial position, the tray moving assembly works to drive the tray to move, so that the freezing pipe is located below the liquid pumping structure, and liquid is pumped out to the freezing pipe through the liquid pumping structure.

Compared with the prior art, the invention has the beneficial effects that: according to the invention, by arranging the liquid pumping structure and the liquid separating structure, the tray moving assembly drives the tray to move, and the liquid injection moving assembly is matched with the tray to drive the liquid injection head to move, so that the liquid injection head can pump and pump liquid from the freezing storage pipe and/or the liquid storage tank on the tray, the liquid can be automatically subpackaged into the freezing storage pipe, the liquid subpackaging efficiency is improved, and the cell preparation efficiency is further improved.

The invention is further described below with reference to the accompanying drawings and specific embodiments.

Drawings

in order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

Fig. 1 is a schematic perspective view (with the fixing frame removed) of an automatic liquid dispensing mechanism according to an embodiment of the present invention;

Fig. 2 is a schematic diagram of an explosive structure of an automatic liquid dispensing mechanism according to an embodiment of the present invention (with the fixing frame removed);

FIG. 3 is a schematic perspective view of a pump structure according to an embodiment of the present invention;

Fig. 4 is a schematic perspective view of a tray according to another embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings and the detailed description.

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.

furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be connected or detachably connected or integrated; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above should not be understood to necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples described in this specification can be combined and combined by one skilled in the art.

As shown in the specific embodiments of fig. 1 to 4, the automatic liquid split charging mechanism provided in this embodiment may be used in a process of split charging a culture solution in a cell preparation process, and may also be used in other scenarios, for example, a scenario of split charging a culture solution in a laboratory, and when being used in a cell preparation process, may be used in an environment with a cleanliness of one hundred, so as to achieve injection of a liquid into the cryopreservation tube 30 or suction of a liquid from the cryopreservation tube 30.

Referring to fig. 1, the automatic liquid dispensing mechanism includes a fixing frame, a liquid pumping structure and a liquid separating structure, the liquid pumping structure and the liquid separating structure are respectively connected to the fixing frame, the liquid separating structure includes a tray 40 for placing the freezing storage tube 30 and the liquid storage tank 20 and a tray moving assembly for driving the tray 40 to move, and the liquid pumping structure is located above the tray 40; when liquid needs to be subpackaged, the tray moving assembly works to drive the tray 40 to move, so that the liquid storage tank 20 is located below the liquid pumping structure, after the liquid storage tank 20 is pumped by the liquid pumping structure, the tray moving assembly works to drive the tray 40 to move, so that the freezing pipe 30 is located below the liquid pumping structure, and liquid is pumped out of the liquid pumping structure to the freezing pipe 30.

In the initial state, the liquid pumping structure is located above the liquid separating structure and is at a certain distance from the tray 40, when the freezing tube 30 and the liquid storage tank 20 on the tray 40 are placed in place, the tray moving assembly moves on the X axis and the Y axis to enable the liquid storage tank 20 to be placed under the liquid pumping structure, the liquid pumping structure can automatically pump liquid after moving downwards, the liquid is pumped from the liquid storage tank 20 and temporarily stored in the liquid pumping structure, the liquid pumping structure stops pumping the liquid after the liquid with the corresponding volume is pumped each time by timing matched with the liquid pumping speed and the like, the liquid pumping structure moves upwards, when the tray moving assembly moves in place, the tray moving assembly works to drive the tray 40 to move, the liquid in the liquid pumping structure can be automatically pumped after the liquid pumping structure moves downwards, the liquid temporarily stored in the liquid pumping structure is pumped out and stored in the freezing tube 30, adopt the speed of timing cooperation pump-out liquid to pump out liquid in the liquid structure, afterwards, the liquid structure of pump moves up in order to resume initial condition to this automatic partial shipment process of accomplishing whole liquid improves the efficiency of liquid partial shipment, and then realizes the purpose that improves the efficiency of cell preparation.

In an embodiment, referring to fig. 3, the liquid pumping structure includes a liquid injection head 15, a liquid injection power source, a liquid injection mounting plate, and a liquid injection moving assembly, the liquid injection moving assembly is connected to the fixing frame, the liquid injection power source and the liquid injection head 15 are respectively connected to the liquid injection mounting plate, and the liquid injection mounting plate is connected to the liquid injection moving assembly.

In this embodiment, the number of the liquid injection heads 15 is several, so as to pump out multiple liquid portions at a time, and of course, the opening width of the liquid storage tank 20 needs to satisfy the requirement that all the liquid injection heads 15 can enter or exit simultaneously.

In this embodiment, the injection power source includes a peristaltic pump, and the peristaltic pump pumps or pumps out liquid to achieve the purpose of automatically pumping liquid.

In an embodiment, referring to fig. 3, the liquid injection mounting plate includes a first vertical connecting section 12, a horizontal connecting section 13, and a second vertical connecting section 14, which are connected in sequence, the first vertical connecting section 12 is connected to the liquid injection moving assembly, and the liquid injection head 15 and the liquid injection power source are connected to the second vertical connecting section 14.

The liquid injection mounting plate formed by connecting the first vertical connecting section 12, the horizontal connecting section 13 and the second vertical connecting section 14 can enable the liquid injection head 15 to be away from the fixing frame by a certain distance, so that the liquid injection head 15 can be smoothly inserted into the liquid storage tank 20 and the freezing storage pipe 30.

In one embodiment, referring to FIG. 3, the lower end of the liquid injection head 15 extends to below the second vertical connecting section 14. So that the entire pouring head 15 can be inserted into the liquid reservoir 20 and the freezing cylinder 30 as a whole.

In one embodiment, the liquid injection moving assembly comprises a liquid injection servo module 10, the liquid injection servo module 10 is connected with the fixed frame through a liquid injection mounting bracket 11, and the first vertical connecting section 12 is connected to the liquid injection servo module 10. The liquid injection servo module 10 is provided with a liquid injection sliding block, the liquid injection mounting plate is connected in the liquid injection sliding block, and the liquid injection head 15 can move up and down by sliding the liquid injection sliding block on the homepage servo module.

In one embodiment, the tray 40 is provided with a plurality of insertion holes and a tank bracket, the tray moving assembly is connected with a tray mounting plate 50, and the tray 40 is connected with the tray mounting plate 50. The tank body support is used for fixing the liquid storage tank 20, and the insertion holes are used for fixing the freezing storage pipes 30.

Specifically, the tank support includes a plurality of columns 41, a plurality of columns 41 and a tray 40 enclosing a cavity for the liquid storage tank 20 to be placed therein, and the tray 40 is provided with a fixing hole disposed in the cavity for positioning and fixing the conical liquid storage tank 20.

In one embodiment, referring to fig. 2, the tray moving assembly includes an X-axis servo module 70 and a Y-axis servo module 60, wherein the X-axis servo module 70 is connected to the fixing frame, and the Y-axis servo module 60 is connected to the X-axis servo module 70. By means of the matching of the X-axis servo module 70 and the Y-axis servo module 60, the tray 40 can move on the X axis and the Y axis and can be matched with the liquid injection moving assembly to achieve the purpose of automatically pumping liquid.

In one embodiment, referring to fig. 2, the X-axis servo module 70 is connected to the fixing frame through an X-axis connection base 72. The Y-axis servo module 60 is connected to the X-axis servo module 70 through a Y-axis connection base.

In one embodiment, a protective cover 71 is disposed on the periphery of the X-axis servo module 70 to protect the X-axis servo module 70 from dust.

Specifically, due to the positions of the tray mounting plate 50, the insertion holes on the tray 40, and the tank holders, the distances of each movement of the X-axis servo module 70, the Y-axis servo module 60, and the injection servo module 10 can be set.

Of course, in other embodiments, a plurality of sensors may be disposed on the fixing frame to detect and position the tray 40 and the liquid injection head 15, so as to perform corresponding detection on the moved positions, and further achieve the purpose of automatically dispensing liquid.

In another embodiment, referring to fig. 4, the tray 40 is provided with a plurality of insertion holes for placing the freezing tubes 30.

The tray 40 is connected to the tray mounting plate 50 by a fastener such as a screw.

In an embodiment, referring to fig. 1 and fig. 2, the second vertical connecting section 14 is provided with a clamping jaw 141, and the liquid injection head 15 is inserted into the clamping jaw 141 to fix the liquid injection head 15.

In the initial state, when the freezing tube 30 and the liquid storage tank 20 on the tray 40 are placed in place, the tray moving assembly moves on the X axis and the Y axis to enable the liquid storage tank 20 to be placed under the liquid injection head 15, the liquid injection head 15 can automatically pump liquid after the liquid injection moving assembly moves downwards, the liquid is pumped from the liquid storage tank 20 and temporarily stored in the liquid pumping structure, after the liquid with the corresponding volume is pumped each time by adopting timing matched with the liquid pumping speed and the like, the liquid injection head 15 stops pumping the liquid, the liquid injection moving assembly moves upwards, when the tray moving assembly moves in place, the tray moving assembly works to drive the tray 40 to move, and further after the freezing tube 30 moves under the liquid pumping structure, the liquid injection head 15 can automatically pump the liquid temporarily stored in the liquid pumping structure and stored in the freezing tube 30, and all the liquid in the liquid pumping structure is pumped out by adopting timing matched with the liquid pumping speed, thereafter, annotate liquid removal subassembly and upwards remove to make and annotate liquid head 15 and resume initial condition, accomplish the automatic partial shipment process of whole liquid with this, improve the efficiency of liquid partial shipment, and then realize improving the purpose of the efficiency of cell preparation.

Foretell automatic partial shipment mechanism of liquid through setting up pump liquid structure and dividing the liquid structure, moves the subassembly by the tray and drives tray 40 and remove, and the cooperation is annotated liquid and is moved the removal that the subassembly drove notes liquid head 15, realizes annotating liquid head 15 and carry out the pump of liquid and get and pump out in freezing pipe 30 and/or the liquid storage pot 20 on tray 40, realizes automatic partial shipment liquid to freezing in the pipe 30, improves liquid partial shipment efficiency, further improves the efficiency of cell preparation.

In one embodiment, the working method of the automatic liquid split charging mechanism is further included, and the working method comprises the following steps:

When liquid split charging is needed, the tray moving assembly works to drive the tray 40 to move, so that the liquid storage tank 20 is located below the liquid pumping structure, the liquid pumping structure pumps the liquid storage tank 20 and then returns to the initial position, the tray moving assembly works to drive the tray 40 to move, so that the freezing pipe 30 is located below the liquid pumping structure, and liquid is pumped out of the liquid pumping structure to the freezing pipe 30.

it should be noted that, as can be clearly understood by those skilled in the art, the specific implementation process of the working method of the automatic liquid dispensing mechanism may refer to the corresponding description in the foregoing embodiment of the automatic liquid dispensing mechanism, and for convenience and brevity of description, no further description is provided herein.

The technical contents of the present invention are further illustrated by the examples only for the convenience of the reader, but the embodiments of the present invention are not limited thereto, and any technical extension or re-creation based on the present invention is protected by the present invention. The protection scope of the invention is subject to the claims.

Claims (10)

1. The automatic liquid split charging mechanism is characterized by comprising a fixing frame, a liquid pumping structure and a liquid separating structure, wherein the liquid pumping structure and the liquid separating structure are respectively connected to the fixing frame; when liquid needs to be subpackaged, the tray moving assembly works to drive the tray to move so that the liquid storage tank is located below the liquid pumping structure, after the liquid storage tank is pumped by the liquid pumping structure, the tray moving assembly works to drive the tray to move so that the freezing storage pipe is located below the liquid pumping structure, and liquid is pumped out to the freezing storage pipe by the liquid pumping structure.

2. The automatic liquid subpackaging mechanism according to claim 1, wherein the liquid pumping structure comprises a liquid injecting head, a liquid injecting power source, a liquid injecting mounting plate and a liquid injecting moving assembly, the liquid injecting moving assembly is connected to the fixing frame, the liquid injecting power source and the liquid injecting head are respectively connected to the liquid injecting mounting plate, and the liquid injecting mounting plate is connected with the liquid injecting moving assembly.

3. The automatic liquid subpackaging mechanism according to claim 2, wherein the liquid injection mounting plate comprises a first vertical connecting section, a horizontal connecting section and a second vertical connecting section which are sequentially connected, the first vertical connecting section is connected with the liquid injection moving assembly, and the liquid injection head and the liquid injection power source are connected with the second vertical connecting section.

4. The automatic dispensing mechanism of claim 3, wherein the lower end of the filling head extends below the second vertical connecting section.

5. The automatic liquid subpackaging mechanism according to claim 4, wherein the liquid injecting moving assembly comprises a liquid injecting servo module, the liquid injecting servo module is connected with the fixed frame through a liquid injecting mounting bracket, and the first vertical connecting section is connected to the liquid injecting servo module.

6. the automatic liquid subpackaging mechanism according to any one of claims 1 to 5, wherein a plurality of jacks and a tank body support are arranged on the tray, a tray mounting plate is connected to the tray moving assembly, and the tray is connected with the tray mounting plate.

7. The mechanism of claim 6, wherein the tray moving assembly comprises an X-axis servo module and a Y-axis servo module, the X-axis servo module is connected to the fixing frame, and the Y-axis servo module is connected to the X-axis servo module.

8. The automatic liquid dispensing mechanism according to claim 7, wherein the X-axis servo module is connected to the fixing frame through an X-axis connecting seat.

9. The automatic dispensing mechanism of claim 7, wherein the Y-axis servo module is connected to the X-axis servo module through a Y-axis connection seat.

10. The working method of the automatic liquid split charging mechanism is characterized by comprising the following steps:

When liquid split charging is needed, the tray moving assembly works to drive the tray to move, so that the liquid storage tank is located below the liquid pumping structure, the liquid pumping structure pumps the liquid storage tank and then returns to an initial position, the tray moving assembly works to drive the tray to move, so that the freezing pipe is located below the liquid pumping structure, and liquid is pumped out to the freezing pipe through the liquid pumping structure.