CN110522678A - A kind of Jasmine long-acting mosquito-driving agent and preparation method thereof - Google Patents
A kind of Jasmine long-acting mosquito-driving agent and preparation method thereof Download PDFInfo
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention belongs to daily chemical product fields, and in particular to a kind of Jasmine long-acting mosquito-driving agent and preparation method thereof is prepared from the following raw materials in parts by weight: 5-7 parts of jasmine essential oil；10-20 parts of wormwood essential oil；10-15 parts of peppermint oil；5-10 parts of clove oil；3-6 parts of pepper volatile oil；2-3 parts of emulsifier；0.5-1.5 parts of preservative；14-17 parts of Arabic gum；14-17 parts of beta-cyclodextrin；1-3 parts of chitosan.It is that main mosquito repellent raw material is prepared that the Jasmine long-acting mosquito-driving agent, which is with plants essential oil, is free of common chemical insecticide, safe and environment-friendly, pollution-free, jasmine aroma with comfortable, naturally perfume is dissipated, and repelling effect duration is long, repelling effect is significant, long-acting.
Description
Technical field
The invention belongs to daily chemical product fields, and in particular to a kind of Jasmine long-acting mosquito-driving agent and preparation method thereof.
Background technique
Summer arrives, and the mosquito as one of " four pests " brings very big harm to people's lives.At present in the world about
There are more than 3500 kinds of mosquitoes and its a subspecies, the most common mosquito has Aedes, Culex and an Anopheles, and mosquito sucks people and various dynamic
The blood of object harasses the mankind and to propagate malaria, filariasis, Japanese Type-B encephalitis, West nile virus disease, dengue fever etc. with this more
Kind disease.The insects such as mosquito bring to human and animal creates disturbances to, injures and life threat, can also cause such as to influence sleep, pass
Broadcast the influence such as disease, welding.
For a long time, people control mosquito using various methods, and commonly resisting method has chemical mosquito repellent and physics to keep away mosquito.
Chemical mosquito repellent, for example using mosquito-repellent incense, electric mat, mosquito repellent liquid, mosquitocide aerosol etc., principle is by addition Metadelphene, removes
The chemical components such as worm pyrethroids, cypermethrin play the role of mosquito repellent desinsection, but the use of such method can often bring toxicity to ask
Topic, containing the ingredient being harmful to the human body, especially to specific groups such as pregnant woman, infants, there are poisoning hidden danger.And using this
The problem of when class method, mosquito is easy to produce resistance, and long-time service will cause serious environmental pollution, causes environmental protection aspect.Object
Reason keeps away mosquito, such as can effectively be resisted mosquito using the methods of mosquito net, mosquito repelling lamp and is created disturbances to, also without chemicals, but mosquito net
Using trouble, and the air circulation in mosquito net is stale slowly, mosquito repelling lamp uses the limited time in night, and vulnerable to other light sources shadow
It rings, to interfere repelling effect.Therefore, a nontoxic, harmless, safety-type mosquito repellent product is particularly important in summer, it
Good effectiveness can not only be played, it is more importantly seldom to the health hazards of human body, even without side effect, simultaneously for environment
There is no any pollution.
Plants essential oil refers to a kind of volatile flavour for refining and extracting from the flower of plant, leaf, stem, root or fruit
Matter, domestic and international researcher have found that various plants and its essential oil have mosquito and certain drive, refuse to keep away and smoke effect of catching up with, and tool
Have and safety is educated to people, is not likely to produce drug resistance, in a natural environment degradable feature.Thus much made of plants essential oil
Scent mosquito repellent product the sixth of the twelve Earthly Branches is widely used in household bedroom, the occasions such as office, hospital, outdoor.However existing scent mosquito repellent
Product, generally existing component is more, at high cost and mosquito repellent low efficiency, fragrance dullness put down the problems such as weary.Along with certain with higher
The most fragrance of folk prescription essential oil of mosquito repellent efficiency is strong, stimulates, and makes us using discomfort, existing essential oil mosquito repellent class product formula does not conform to
Reason, repelling effect, which is difficult to, to be continued.And essential oil product is as liquid form product, and extremely strong volatility is also brought to using
Inconvenience, directly also very short by mosquito-repellent action time of plants essential oil, generally at 1~2 hour, repelling effect is bad, because
This is also difficult to the requirement for meeting the majority of consumers.
Summary of the invention
It is an object of the invention to there are problem and shortage, provided for above-mentioned it is a kind of with jasmine essential oil, wormwood essential oil,
What wintergreen etc. was prepared as a raw material, significant, long-acting, safe and non-toxic, without intense stimulus fragrance the Jasmine of repelling effect is long
Imitate culicifuge and preparation method thereof.
In order to achieve the object of the present invention, the present invention adopts the following technical scheme:
A kind of Jasmine long-acting mosquito-driving agent, is prepared from the following raw materials in parts by weight:
5-7 parts of jasmine essential oil；10-20 parts of wormwood essential oil；10-15 parts of peppermint oil；5-10 parts of clove oil；Pepper volatile oil 3-
6 parts；2-3 parts of emulsifier；0.5-1.5 parts of preservative；15-20 parts of Arabic gum；15-20 parts of beta-cyclodextrin；1-3 parts of chitosan.
Above-mentioned Jasmine long-acting mosquito-driving agent, the emulsifier are emulsifier op-10；The preservative is nipalgin
Ethyl ester.
Steps are as follows for the preparation method of the Jasmine long-acting mosquito-driving agent:
(1) each raw material for standby is taken in parts by weight, and jasmine essential oil, wormwood essential oil, peppermint oil, clove oil and Chinese prickly ash are volatilized
Oil is mixed to get mixed liquor A；
(2) water of 60 DEG C of addition stirs to dissolve and beta-cyclodextrin saturated solution is made in beta-cyclodextrin；Then while stirring
Mixed liquor A at the uniform velocity and is added slowly in beta-cyclodextrin saturated solution, is stirred evenly, is placed on magnetic stirring apparatus and stirs
25-35 minutes, obtain mixed emulsion B；
(3) Arabic gum is taken, suitable water is added, solution is formed and is added to mixed emulsion after solution temperature is heated up to 60 DEG C
In B, while chitosan, emulsifier and preservative is added, is mixed evenly, is put into homogenizer homogeneous 10-15 under 20Mpa
Minute, then half an hour is stood under room temperature；
(4) resulting material is dried, is placed in pelletizer and is granulated, Jasmine long-acting mosquito-driving agent can be obtained.
In the present invention, jasmine essential oil used is from jasmine plant (Classification system Jasminum sambac (L.)
Ait.) spend middle extraction, belong to Oleaceae, jasmine essential oil fragrant taste is charming, helps to pacify nerve, can releive gloomy
Mood inspires enthusiasm, promotes self-confidence, antidepression.It can nurse and improve simultaneously dry skin, water shortage, excessively oil and sensitive shape
Condition desalinates striae of pregnancy and scar, increases skin elasticity, skin is allowed to feel more tender.The fragrance of Jasmine has the effect of mosquito repellent, In
Jasmine essential oil is added in the present invention can not only improve the repelling effect of preparation-obtained culicifuge but also assign mosquito repellent
The light jasmin of agent makes culicifuge have effects that calm the nerves.
The wormwood essential oil be from the leaf of wormwood (scientific name: Artemisia argyi H. L é v. & Vaniot),
The extract of stem, extrusion and solvent extraction method refine the volatile flavor of extraction.Folium artemisiae argyi has antibacterial and antiviral work
With；It relievings asthma, antibechic and phlegm-dispelling functions；Hemostasis and blood coagulation resisting function；Calm and anti-allergic effects；Protect liver choleretic effect etc..Wormwood
With a kind of special fragrance, this special fragrance has effects that mosquito dispersing, and wormwood has special fragrance taste, is made into fragrance
Pillow helps there are also sleeping and sleeps the effect of recovering from fatigue.Wormwood leaf extractive, then dilution is watered shower, can be except small red pimple long with it.
Additionally it can prevent disease with mosquito repellent fly, sterilization.Wormwood essential oil has rationale blood, warm meridians, and dispellieg cold and dampness relieves pain, and resists
The effect of bacterium, anti-inflammatory motivate glandula digestive, and relieving cough and reducing sputum promotees to recycle, tonifying Qi, promotes immunity.
Peppermint oil is that the fresh stem of Lamiaceae plant peppermint (Mentha haplocalyx Briq.) and Ye Jing vapor steam
Evaporate oily, peppermint plays the role of desensitization, anti-inflammatory and antibacterial to bite by mosquitos skin；Also there is apparent stop to the infection of the upper respiratory tract
Cough, anti-inflammatory and bacteriostasis；There are swelling and pain relieving, antiphlogistic antibacterial to hemorrhoid, anal fissure.Peppermint oil is colourless or flaxen
Supernatant liquid has special refrigerant fragrance, is commonly used for expelling mosquito, alleviates physical fatigue, Peppermint essential oil, which has, soothes the spirit, relieves stress
And the effect of Vermins-proof and mosquito-driving, salubrious taste can be very good purification air, remove stink, by peppermint essence oil droplet in sponge,
There is good expelling mosquito in place more than room or mosquito.
Clove oil is by Myrtaceae Syzygium arbor cloves (Syzygium aromaticum. different name Eugenia
Aromaticu m. or Eugenia caryophyllata.) it refines, toothache, bronchitis, neuralgia, stomach can be treated
Acid mitigates discomfort and pain caused by dysentery, improves weak constitution and anaemia, expelling parasite promotes blood circulation.Clove oil has
Good deodorization can be instilled in water with expelling mosquito, hot summer with clove oil due to the pleasant aroma of cloves
It baths, light fragrance can not only bring body note, and relieving mood can also effective mosquito proof.
The pepper volatile oil refers to from Chinese prickly ash (Classification system Zanthoxylum bungeanum Maxim.) pericarp
The volatile component of middle extraction is it in fragrant and drug effect material base, and pepper volatile oil contains olefines, alcohols, ketone, ester
The various structures type small-molecule substance such as class and epoxies.Japan pepper essential oil causes rotten, pathomycete or bacteria suppression effect to food
Obviously, pepper volatile oil can not only inhibit Gram-negative bacteria, can also inhibit gram-positive bacteria, to such as golden yellow grape of bacterium
Coccus, bacillus subtilis, bacillus cereus, bacillus laterosporus and Escherichia coli can play certain inhibiting effect,
Also there is inhibitory activity to mould and fungi simultaneously, pepper volatile oil has good expelling parasite, insecticidal activity to storage pest, to mosquito
With good repellent effect.
Preservative ethylparaben also known as ethyl-para-hydroxybenzoate used in the present invention, molecular formula C9H10O3, colourless
Crystallization or white crystalline powder, there is mild flavor, slightly astringent taste.Parabens be the preservative that generally uses it
One, it can inhibit the respiratory enzyme of microbial cell and the activity of transmitting enzyme system, and destroy the cell membrane mechanism of microorganism, thus
There is extensive antibacterial action to mould, yeast and bacterium.Ethylparaben be the very strong substance of bactericidal properties, phenol coefficient 8.0,
Toxicity is extremely low, non-stimulated to human skin, and antibacterial ability is stronger than sorbic acid and benzoic acid, and antibacterial action is influenced not by ph value
Greatly, effect is good in the range of ph value 4~8.Ethylparaben is added when making culicifuge by the present invention can be improved mosquito repellent
The antibacterial and mouldproof performance of agent.
Chitosan used in the present invention is also referred to as chitosan, and being chitin sloughs N- acetyl group through concentrated base heat treatment
Product, chemical name is Chitosan (1-4) -2- amino-B-D glucose, and adhesive, thickener, steady is used as in industry
Determine agent, gelling agent etc., also serves as the mould inhibitor of acidic materials.Chitosan has good bioadhesive biocompatibility biology
Degradability and preferable film forming, due to its superior functional character and unique molecular structure, chitosan is used as can biology
Degradable material is used for novel Drug Delivery Systems, is greatly improved curative effect of medication by changing administration route, there is control release to increase
Targeting reduces stimulation and reduces toxic side effect, and improves the effects of hydrophobic drug increases medicine stability by cell membrane
The characteristics of.
The beneficial effect comprise that:
1, a kind of Jasmine long-acting mosquito-driving agent of the present invention is with plants essential oils such as jasmine essential oil, wormwood essential oil, pepper volatile oils
It is prepared for main mosquito repellent raw material, is free of common chemical insecticide, safe and environment-friendly, pollution-free and used raw material pair
Mosquito has good dispersion effect, does not stimulate skin, can also play the role of calming the nerves to human body recovering from fatigue.
2, the various raw materials used in the present invention, which rationally assemble, makes its use, can play synergistic effect, and effectively
Solve the problems, such as single plant essential oil there are inefficiency and fragrance are single, repelling effect is good, and by using me
Primary glue, beta-cyclodextrin and chitosan carry out microencapsulation processing to plants essential oil, overcome the volatilization that essential oil fragrance is strong, strong
Property, stimulation, mosquito repelling action time short deficiency, so that the Jasmine long-acting mosquito-driving agent being prepared is without strong, stimulation is fragrant
Gas.By being used in compounding for several essential oils, so that the culicifuge being prepared has the jasmine aroma of comfortable, dissipate naturally
Perfume (or spice), and repelling effect duration is long, and repelling effect is good.
3, the Jasmine long-acting mosquito-driving agent being prepared using the method for the present invention is all very convenient using carrying, safe and non-toxic,
It is harmless, it is without side-effects to human body, simultaneously for environmental nonpollution.
Specific embodiment
Embodiment 1
A kind of Jasmine long-acting mosquito-driving agent, is prepared from the following raw materials in parts by weight:
5 parts of jasmine essential oil；10 parts of wormwood essential oil；10 parts of peppermint oil；5 parts of clove oil；3 parts of pepper volatile oil；Polyoxyethylene nonylphenol ether-
10 2 parts；0.5 part of preservative ethylparaben；15 parts of Arabic gum；15 parts of beta-cyclodextrin；1 part of chitosan.
Steps are as follows for the preparation method of the Jasmine long-acting mosquito-driving agent:
(1) each raw material for standby is taken in parts by weight, and jasmine essential oil, wormwood essential oil, peppermint oil, clove oil and Chinese prickly ash are volatilized
Oil is mixed to get mixed liquor A；
(2) water of 60 DEG C of addition stirs to dissolve and beta-cyclodextrin saturated solution is made in beta-cyclodextrin；Then while stirring
Mixed liquor A at the uniform velocity and is added slowly in beta-cyclodextrin saturated solution, is stirred evenly, is placed on magnetic stirring apparatus and stirs 25
Minute, obtain mixed emulsion B；
(3) Arabic gum is taken, suitable water is added, solution is formed and is added to mixed emulsion after solution temperature is heated up to 60 DEG C
In B, while chitosan, emulsifier and preservative is added, is mixed evenly, is put into homogenizer homogeneous 15 under 20Mpa and divides
Then clock stands half an hour under room temperature；
(4) resulting material is dried, is placed in pelletizer and is granulated, Jasmine long-acting mosquito-driving agent can be obtained.
Embodiment 2
A kind of Jasmine long-acting mosquito-driving agent, is prepared from the following raw materials in parts by weight:
6 parts of jasmine essential oil；15 parts of wormwood essential oil；13 parts of peppermint oil；7 parts of clove oil；5 parts of pepper volatile oil；Polyoxyethylene nonylphenol ether-
10 2.5 parts；1 part of preservative ethylparaben；17 parts of Arabic gum；17 parts of beta-cyclodextrin；2 parts of chitosan.
Steps are as follows for the preparation method of the Jasmine long-acting mosquito-driving agent:
(1) each raw material for standby is taken in parts by weight, and jasmine essential oil, wormwood essential oil, peppermint oil, clove oil and Chinese prickly ash are volatilized
Oil is mixed to get mixed liquor A；
(2) water of 60 DEG C of addition stirs to dissolve and beta-cyclodextrin saturated solution is made in beta-cyclodextrin；Then while stirring
Mixed liquor A at the uniform velocity and is added slowly in beta-cyclodextrin saturated solution, is stirred evenly, is placed on magnetic stirring apparatus and stirs 30
Minute, obtain mixed emulsion B；
(3) Arabic gum is taken, suitable water is added, solution is formed and is added to mixed emulsion after solution temperature is heated up to 60 DEG C
In B, while chitosan, emulsifier and preservative is added, is mixed evenly, is put into homogenizer homogeneous 13 under 20Mpa and divides
Then clock stands half an hour under room temperature；
(4) resulting material is dried, is placed in pelletizer and is granulated, Jasmine long-acting mosquito-driving agent can be obtained.
Embodiment 3
A kind of Jasmine long-acting mosquito-driving agent, is prepared from the following raw materials in parts by weight:
7 parts of jasmine essential oil；20 parts of wormwood essential oil；15 parts of peppermint oil；10 parts of clove oil；6 parts of pepper volatile oil；Emulsifier
3 parts of OP-10；1.5 parts of preservative ethylparaben；20 parts of Arabic gum；20 parts of beta-cyclodextrin；3 parts of chitosan.
Steps are as follows for the preparation method of the Jasmine long-acting mosquito-driving agent:
(1) each raw material for standby is taken in parts by weight, and jasmine essential oil, wormwood essential oil, peppermint oil, clove oil and Chinese prickly ash are volatilized
Oil is mixed to get mixed liquor A；
(2) water of 60 DEG C of addition stirs to dissolve and beta-cyclodextrin saturated solution is made in beta-cyclodextrin；Then while stirring
Mixed liquor A at the uniform velocity and is added slowly in beta-cyclodextrin saturated solution, is stirred evenly, is placed on magnetic stirring apparatus and stirs 35
Minute, obtain mixed emulsion B；
(3) Arabic gum is taken, suitable water is added, solution is formed and is added to mixed emulsion after solution temperature is heated up to 60 DEG C
In B, while chitosan, emulsifier and preservative is added, is mixed evenly, is put into homogenizer homogeneous 10 under 20Mpa and divides
Then clock stands half an hour under room temperature；
(4) resulting material is dried, is placed in pelletizer and is granulated, Jasmine long-acting mosquito-driving agent can be obtained.
Embodiment 4
A kind of Jasmine long-acting mosquito-driving agent, is prepared from the following raw materials in parts by weight:
5 parts of jasmine essential oil；20 parts of wormwood essential oil；10 parts of peppermint oil；10 parts of clove oil；4 parts of pepper volatile oil；Emulsifier
2.7 parts of OP-10；1.2 parts of preservative ethylparaben；18 parts of Arabic gum；18 parts of beta-cyclodextrin；1.5 parts of chitosan.
Steps are as follows for the preparation method of the Jasmine long-acting mosquito-driving agent:
(1) each raw material for standby is taken in parts by weight, and jasmine essential oil, wormwood essential oil, peppermint oil, clove oil and Chinese prickly ash are volatilized
Oil is mixed to get mixed liquor A；
(2) water of 60 DEG C of addition stirs to dissolve and beta-cyclodextrin saturated solution is made in beta-cyclodextrin；Then while stirring
Mixed liquor A at the uniform velocity and is added slowly in beta-cyclodextrin saturated solution, is stirred evenly, is placed on magnetic stirring apparatus and stirs 30
Minute, obtain mixed emulsion B；
(3) Arabic gum is taken, suitable water is added, solution is formed and is added to mixed emulsion after solution temperature is heated up to 60 DEG C
In B, while chitosan, emulsifier and preservative is added, is mixed evenly, is put into homogenizer homogeneous 15 under 20Mpa and divides
Then clock stands half an hour under room temperature；
(4) resulting material is dried, is placed in pelletizer and is granulated, Jasmine long-acting mosquito-driving agent can be obtained.
Repelling effect experiment
(1) laboratory sample: Jasmine long-acting mosquito-driving agent that 1-4 of the embodiment of the present invention is prepared, certain commercially available mosquito-repellent perfume.
(2) for test worm kind and strain: aedes albopictus (Aedes albopictus), the sensitive strain standard of laboratory rearing
Test worm, -5 days 4 days female insects that do not suck blood after emergence.
(3) test method:
1. attack is tested: mosquito 500 are put into 60 × 45 × 45cm mosquito cage, hand is protruded into 2min in mosquito cage by volunteer,
More than 30 persons of the test worm for stopping falling of coming are that attack is qualified, and this person and this mosquito can be used for mosquito repellent test.
2. according to GB/T 13917.9-2009 (" agriculture chemical registration hygienic insecticide indoor pharmacodynamic test and evaluation the 9th
Point: repellant ") test method tested, the volunteer of every group of the repellency test attack qualification of selection 10 tests,
Men and women is fifty-fifty.Jasmine long-acting mosquito-driving agent of the invention is packed into ventilative pouch (50mm*30mm, culicifuge in experimentation
The amount of being put into be sack capacity 1/5) in, volunteer is grasp with hand；And certain commercially available mosquito-repellent perfume then can Direct Uniform sprinkling
In on the exposed skin of volunteer's the back of the hand.Record the mean up time of repellent.
(4) experimental result
Above-mentioned each product is as shown in table 1 below to the effective protecting time of volunteer:
The repelling effect for the Jasmine long-acting mosquito-driving agent being prepared using the method for the present invention is good, repelling effect duration
It is long, hence it is evident that be better than certain commercially available mosquito-repellent perfume.
Claims (4)
1. a kind of Jasmine long-acting mosquito-driving agent, which is characterized in that be prepared from the following raw materials in parts by weight:
5-7 parts of jasmine essential oil；10-20 parts of wormwood essential oil；10-15 parts of peppermint oil；5-10 parts of clove oil；Pepper volatile oil 3-
6 parts；2-3 parts of emulsifier；0.5-1.5 parts of preservative；14-17 parts of Arabic gum；14-17 parts of beta-cyclodextrin；1-3 parts of chitosan.
2. Jasmine long-acting mosquito-driving agent according to claim 1, which is characterized in that the emulsifier is polyoxyethylene nonylphenol ether-
10。
3. Jasmine long-acting mosquito-driving agent according to claim 1, which is characterized in that the preservative is nipalgin second
Ester.
4. Jasmine long-acting mosquito-driving agent according to claim 1, which is characterized in that the Jasmine long-acting mosquito-driving agent
Steps are as follows for preparation method:
(1) each raw material for standby is taken in parts by weight, and jasmine essential oil, wormwood essential oil, peppermint oil, clove oil and Chinese prickly ash are volatilized
Oil is mixed to get mixed liquor A；
(2) water of 60 DEG C of addition stirs to dissolve and beta-cyclodextrin saturated solution is made in beta-cyclodextrin；Then while stirring
Mixed liquor A at the uniform velocity and is added slowly in beta-cyclodextrin saturated solution, is stirred evenly, is placed on magnetic stirring apparatus and stirs
25-35 minutes, obtain mixed emulsion B；
(3) Arabic gum is taken, suitable water is added, solution is formed and is added to mixed emulsion after solution temperature is heated up to 60 DEG C
In B, while chitosan, emulsifier and preservative is added, is mixed evenly, is put into homogenizer homogeneous 10-15 under 20Mpa
Minute, then half an hour is stood under room temperature；
(4) resulting material is dried, is placed in pelletizer and is granulated, Jasmine long-acting mosquito-driving agent can be obtained.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910993442.3A CN110522678A (en) | 2019-10-18 | 2019-10-18 | A kind of Jasmine long-acting mosquito-driving agent and preparation method thereof |
Applications Claiming Priority (1)
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| CN113854307A (en) * | 2021-10-20 | 2021-12-31 | 于军武 | Long-acting slow-release bird repellent and preparation method thereof |
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| CN113854307A (en) * | 2021-10-20 | 2021-12-31 | 于军武 | Long-acting slow-release bird repellent and preparation method thereof |
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