CN110494174A - The determination method and decision maker of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment - Google Patents
The determination method and decision maker of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment Download PDFInfo
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- CN110494174A CN110494174A CN201880023899.5A CN201880023899A CN110494174A CN 110494174 A CN110494174 A CN 110494174A CN 201880023899 A CN201880023899 A CN 201880023899A CN 110494174 A CN110494174 A CN 110494174A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
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Abstract
The present invention provides the determination method and decision maker that the connection status of replenisher pipeline and blood circuit can be simply determined in haemodialysis equipment.The determination method of the connection status of replenisher pipeline 140 and blood circuit 110A in haemodialysis equipment 100A includes: pump work process, wherein, it is connect in the one end of arterial side pipeline 111 with the one end of venous side pipeline 112, it is not filled by the blood circuit 110A of the state of liquid, blood pump 111a and fluid infusion is made to pump 140a work;Bubble detects process, wherein after making blood pump 111a and fluid infusion pump 140a work, in the state of after preset 1st time, carries out bubble detection by air-foam detector 111b (112b);And judgment process, wherein according to whether detecting that bubble determines that replenisher pipeline 140 is to connect with arterial side pipeline 111 or connect with venous side pipeline 112.
Description
Technical field
The present invention relates to the determination method of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment and sentence
Determine device.
Background technique
In the past, haemodialysis equipment was mainly made of components described below: dialyzer or hemodialysis filter
Haemodialysers such as (hemodialysis filter), purify the blood of patient;Blood circuit, it is saturating with blood
Parser connection, for making the blood circulation of patient;Dialysis fluid circuit is used to that dialyzate to be imported and exported to haemodialyser;
And replenisher pipeline, it is used for the replenisher of amount corresponding with the amount of moisture removed by haemodialyser to blood circuit
Liquor charging.
Using haemodialysis equipment carry out blood filtration dialysis in addition to using physiological saline as the offline mode of replenisher with
Outside, it is known that using dialyzate as the online mode of replenisher (referring to patent document 1).In addition, liquor charging of the replenisher to blood circuit
Method is divided into the position to blood circuit injection replenisher in the preceding dilution mode of the upstream side of haemodialyser and in downstream side
Two kinds of rear dilution mode.
In the case where preceding dilution mode, blood enters haemodialyser after being diluted by replenisher, and is filtered.Cause
This, is not susceptible to pachyemia in haemodialyser, and on the other hand, so that haemoconcentration is lower to equal in supplement liquid measure
In the case where, compared with rear dilution mode, the removal efficiency of level of uremic substances declines.In order to improve removal efficiency, with rear dilution
The case where mode, the supplement liquid measure treated each time was usually 24~96 liters compared to a large amount of replenisher is needed.
On the other hand, in the case where rear dilution mode, blood, which is not diluted, enters haemodialyser, is being filtered
Afterwards, it is diluted corresponding to water removal using replenisher.Due to pachyhematous degree not to occur in haemodialyser
By moisture removal, therefore supplement liquid measure is few compared with preceding dilution mode, and the supplement liquid measure treated each time is 20 liters or so.
Existing technical literature
Patent document
Patent document 1: Japanese Unexamined Patent Publication 2015-80595 bulletin
Summary of the invention
As it appears from the above, supplement liquid measure is different according to feeding method, therefore there are the companies of replenisher pipeline and blood circuit
A possibility that wrong accidentally leads to substantial risk.As a result, when the circuit of haemodialysis equipment assembles, need to confirm supplement liquid pipe
The operation whether corresponding with feeding method of the connection status of line and blood circuit.
But the blood circuit, dialysis fluid circuit after assembling are installed on haemodialysis equipment in a complex manner, are difficult wink
Between visually judge whether replenisher pipeline connect with blood circuit in correct position.
Therefore, the object of the present invention is to provide one kind can simply determine that replenisher pipeline is connect with blood circuit
Connection status determination method and decision maker.
It is described the present invention relates to the determination method of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment
Haemodialysis equipment has: haemodialyser;Blood circuit, with the connection of the artery of one end and object and another side
The arterial side pipeline and one end connecting with the haemodialyser are connect with the haemodialyser and another side and object
The venous side pipeline of the Connect of Vein of person;Blood pump is configured in the arterial side pipeline;Dialysis fluid circuit has to institute
Haemodialyser is stated to import the dialyzate importing pipeline of dialyzate and lead from the dialyzate of haemodialyser export dialyzate
Pipeline out;Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, and the conveying of Xiang Suoshu blood circuit is mended
Filling liquid;Fluid infusion pump, configures in the replenisher pipeline;And air-foam detector, it configures in the arterial side pipeline or institute
Venous side pipeline is stated, bubble is detected, the determination method includes: pump work process, wherein in the arterial side pipeline
One end connect with the one end of the venous side pipeline and in the blood circuit of the state of underfill liquid, make institute
State blood pump and the fluid infusion pump work;Bubble detects process, wherein after making the blood pump and the fluid infusion pump work,
In the state of after preset 1st time, bubble detection is carried out using the air-foam detector;And determine work
Sequence, wherein whether bubble is detected according to using the air-foam detector, to determine that the replenisher pipeline is moved with described
The connection of arteries and veins side pipe line is still connect with the venous side pipeline.
It is further preferred, that air-foam detector configuration in the arterial side pipeline with the replenisher pipeline
Connecting portion compared to the position for more leaning on one end, in the pump work process, so that replenisher is towards the artery side pipe
The mode of the one end flowing of line makes the blood pump work, in the judgment process, in the case where bubble is not detected
It is determined as that the replenisher pipeline is connect with the arterial side pipeline, the replenisher is determined as in the case where detecting bubble
Pipeline is connect with the venous side pipeline.
Moreover, it relates to which the judgement of the connection status of replenisher pipeline and blood circuit fills in haemodialysis equipment
It sets, the haemodialysis equipment has: haemodialyser;The blood circuit connects with the artery of one end and object
It connects and arterial side pipeline and one end that another side is connect with the haemodialyser is connect and another with the haemodialyser
The venous side pipeline of the Connect of Vein of one end and object;Blood pump is configured in the arterial side pipeline;Dialyzate returns
There is the dialyzate for importing dialyzate to the haemodialyser to import pipeline and export from the haemodialyser and dialyse for road
The dialyzate derivation pipeline of liquid;Replenisher pipeline is connect, Xiang Suoshu blood with the arterial side pipeline or the venous side pipeline
Liquid circuit conveys replenisher;Fluid infusion pump, configures in the replenisher pipeline;And air-foam detector, configuration is described dynamic
Arteries and veins side pipe line or the venous side pipeline, detect bubble, the decision maker has: pump work portion, described dynamic
The one end of arteries and veins side pipe line is connect with the one end of the venous side pipeline and the blood circuit of the state of underfill liquid
In, make the blood pump and the fluid infusion pump work;Bubble test section, using the pump work portion make the blood pump and
After the fluid infusion pump work, in the state of after preset 1st time, bubble is carried out using the air-foam detector
Detection;And determination unit, whether bubble is detected according to using the air-foam detector, to determine the replenisher pipeline
It is to connect with the arterial side pipeline or connect with the venous side pipeline.
It is further preferred, that the air-foam detector configuration is in the arterial side pipeline, the pump work portion is so that supplement
The mode that the one end of liquid towards the arterial side pipeline flows makes the blood pump work, and gas is being not detected in the determination unit
It is determined as that the replenisher pipeline is connect with the arterial side pipeline in the case where bubble, is determined as in the case where detecting bubble
The replenisher pipeline is connect with the venous side pipeline.
Moreover, it relates in haemodialysis equipment the connection status of replenisher pipeline and blood circuit judgement side
Method, the haemodialysis equipment have: haemodialyser;Blood circuit, with the artery of one end and object connection and
The arterial side pipeline and one end is connect with the haemodialyser and the other end that another side is connect with the haemodialyser
The venous side pipeline of the Connect of Vein of side and object;Blood pump is configured in the arterial side pipeline;Dialysis fluid circuit,
Pipeline is imported with the dialyzate for importing dialyzate to the haemodialyser and exports dialyzate from the haemodialyser
Dialyzate derivation pipeline;Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, and Xiang Suoshu blood returns
Road conveys replenisher;Fluid infusion pump, configures in the replenisher pipeline;Arterial side air-foam detector is configured in the artery
Side pipe line, detects bubble;And venous side air-foam detector, configuration carry out bubble in the venous side pipeline
Detection, the determination method includes: pump work process, wherein is filled with liquid and the supplement liquid pipe in the blood circuit
Line is filled in the state of gas, on one side makes dialyzate reverse filtration it saturating from the dialysis fluid circuit injection blood
Parser makes the fluid infusion pump work on one side;Bubble detects process, wherein after making the fluid infusion pump work, starts based on described
The bubble of arterial side air-foam detector and the venous side air-foam detector is detected to detect bubble;And judgment process, wherein
A side in the arterial side air-foam detector or the venous side air-foam detector first detects bubble compared with another party
In the case where, determine that the replenisher pipeline is connect with which side in the arterial side pipeline or the venous side pipeline.
It is further preferred, that being filled with liquid and the supplement liquid pipe in the blood circuit in the pump work process
Line is filled in the state of gas, so that it is injected the blood from the dialysis fluid circuit dialyzate reverse filtration according to one side
Liquid dialyzer makes institute in a manner of being less than the one end that the flow of injection rate of dialyzate makes liquid flow to arterial side pipeline on one side
Blood pump work is stated, and makes the fluid infusion pump work, in the judgment process, is utilizing the arterial side air-foam detector
It is determined as that the replenisher pipeline is connect with the arterial side pipeline in the case where first detecting bubble, is utilizing the venous side
Air-foam detector is determined as that the replenisher pipeline is connect with the venous side pipeline in the case where first detecting bubble.
Moreover, it relates to which the judgement of the connection status of replenisher pipeline and blood circuit fills in haemodialysis equipment
It sets, the haemodialysis equipment has: haemodialyser;Blood circuit, with the artery of one end and object connection and
The arterial side pipeline and one end is connect with the haemodialyser and the other end that another side is connect with the haemodialyser
The venous side pipeline of the Connect of Vein of side and object;Blood pump is configured in the arterial side pipeline;Dialysis fluid circuit,
Pipeline is imported with the dialyzate for importing dialyzate to the haemodialyser and exports dialyzate from the haemodialyser
Dialyzate derivation pipeline;Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, and Xiang Suoshu blood returns
Road conveys replenisher;Fluid infusion pump, configures in the replenisher pipeline;Arterial side air-foam detector is configured in the artery
Side pipe line, detects bubble;And venous side air-foam detector, configuration carry out bubble in the venous side pipeline
Detection, the decision maker have: pump work portion, in the blood circuit filled with liquid and replenisher pipeline filling
In the state of having gas, dialyzate reverse filtration is made on one side it inject the haemodialyser from the dialysis fluid circuit,
Make the fluid infusion pump work on one side;Bubble test section pumps the blood pump and the fluid infusion using the pump work portion
After work, the bubble for starting based on the arterial side air-foam detector and the venous side air-foam detector is detected to detect gas
Bubble;And determination unit, a side and another party in the arterial side air-foam detector or the venous side air-foam detector
In the case where first detecting bubble, determine in the replenisher pipeline and the arterial side pipeline or the venous side pipeline
Which side connection.
It is further preferred, that the pump work portion is filled with liquid in the blood circuit and the replenisher pipeline is filled out
In the state of gas, keep it saturating from the dialysis fluid circuit injection blood dialyzate reverse filtration according to one side
Parser, on one side in a manner of the one end that the flow of the injection rate less than dialyzate makes liquid flow to arterial side pipeline, make described
Blood pump work, and make the fluid infusion pump work, the determination unit after starting bubble detection using the bubble test section,
It is determined as the replenisher pipeline and the artery in the case where first detecting bubble using the arterial side air-foam detector
The connection of side pipe line, the replenisher pipeline is determined as in the case where first detecting bubble using the venous side air-foam detector
It is connect with the venous side pipeline.
It is further preferred, that the liquor charging amount of the fluid infusion pump is less than the liquor charging amount of the blood pump, and it is less than from described
The injection rate of analysis liquid subtracts the amount that the liquor charging amount of the blood pump obtains.
It is further preferred, that being also equipped with: configuration part sets feeding method of the replenisher to the blood circuit;And
Notification unit, it is not corresponding in the feeding method set by the configuration part and the connection status determined using the determination unit
In the case of reported.
The effect of invention
In accordance with the invention it is possible to detect bubble by the air-foam detector for being configured at blood circuit, whether there is or not and based on it
Testing result simply determines the connection status of replenisher pipeline and blood circuit.
Detailed description of the invention
Fig. 1 is the figure for showing the schematic configuration of the haemodialysis equipment in the 1st embodiment.
Fig. 2 is the block diagram for showing the composition of haemodialysis equipment of the decision maker with the 1st embodiment.
Fig. 3 is the figure for showing the flow chart of determination method of the 1st embodiment of the invention.
Fig. 4 A shows the connection status in the circuit in the 1st embodiment in preceding dilution mode.
The connection status in the circuit after Fig. 4 B is shown in the 1st embodiment in dilution mode.
Fig. 5 shows the starting filling (priming) of the blood circuit in the 1st embodiment.
Fig. 6 is the figure for showing the flow chart of determination method of variation of the invention.
Fig. 7 is the figure for showing the schematic configuration of the haemodialysis equipment in the 2nd embodiment.
Fig. 8 is the block diagram for showing the composition of haemodialysis equipment of the decision maker with the 2nd embodiment.
Fig. 9 is the figure for showing the flow chart of determination method of second embodiment of the present invention.
Figure 10 shows the starting filling of the blood circuit in the 2nd embodiment.
Figure 11 A shows the circuit connection status in the preceding diluted situation in the 2nd embodiment.
Figure 11 B shows the circuit connection status in the rear diluted situation in the 2nd embodiment.
Specific embodiment
Explanation has each preferred of the haemodialysis equipment of determination method and decision maker of the invention referring to the drawings
Embodiment.Haemodialysis equipment of the invention purifies the blood of potential renal insufficiency patient, drug poisoning patient, and will
Excessive moisture removal in blood, and (fluid infusion) is kept the skin wet into blood as needed.
In addition, the haemodialysis equipment of present embodiment is continuous by the flowing of the dialyzate in control blood circuit
Automatically it carries out starting filling process, collapse due to massive hemorrhage process, fluid infusion process, the automatic blood dialysis apparatus for returning each process such as blood process.It is logical
Cross by determination method of the invention start filling process in be applied to haemodialysis equipment, can using start fill process come
Determine the connection status of replenisher pipeline and blood circuit.
<the 1st embodiment>
Illustrate the overall structure of the haemodialysis equipment 100A of the 1st embodiment referring to FIG. 1 and FIG. 2.Fig. 1 is to show this hair
The figure of the schematic configuration of haemodialysis equipment 100A in bright 1st embodiment, Fig. 2 are the structures for showing haemodialysis equipment 100A
At block diagram.
As shown in Figures 1 and 2, haemodialysis equipment 100A has: for making blood circuit 110A, the blood of blood flow
Pump 111a, arterial side air-foam detector 111b, venous side air-foam detector 112b, haemodialyser 120, dialysis fluid circuit 130,
Dialyzate liquor charging portion 133, replenisher pipeline 140, fluid infusion pump 140a and the control device 150 as decision maker.
Blood circuit 110A has arterial side pipeline 111, venous side pipeline 112 and tapping line 113.Arterial side pipeline
111, venous side pipeline 112 and tapping line 113 can be circulated with liquid and have based on soft pipe flexible and constituted.
The one end of arterial side pipeline 111 is connect with the blood introducing port 122a of aftermentioned haemodialyser 120.In artery
Side pipe line 111 configures blood pump 111a, arterial side air-foam detector 111b, arterial side fixture 111c and arterial side interconnecting piece
111d。
Blood pump 111a is constituted the pipe of arterial side pipeline 111 by squeezing with roller bearing, thus by arterial side pipeline 111
The blood in portion starts the submitting of the liquid such as servicing fluids.
As long as arterial side air-foam detector 111b is configured at connecting in arterial side pipeline 111 with aftermentioned replenisher pipeline 140
The connecting portion connect, which is compared, more leans on one end (can in the present embodiment, configure in arterial side pipeline 111 and blood pump
111a compares upstream side), to thering is bubble-free to detect in pipe.
Arterial side fixture 111c is configured in the upstream side compared with arterial side air-foam detector 111b.Arterial side fixture
111c is controlled according to the bubble testing result of arterial side air-foam detector 111b, makes the passage opening/closing of arterial side pipeline 111.
Arterial side interconnecting piece 111d configures the another side in arterial side pipeline 111.Arterial side interconnecting piece 111d and puncture
Needle connection in patient vessel.
The one end of venous side pipeline 112 is connect with the blood export mouth 122b of aftermentioned haemodialyser 120.In vein
On side pipe line 112, configuration drip chamber 112a, venous side air-foam detector 112b, venous side fixture 112c and venous side interconnecting piece
112d。
Drip chamber 112a accumulates certain to remove the bubble being mixed into venous side pipeline 112, cakey blood etc.
The blood of amount.
Venous side air-foam detector 112b is configured compared with drip chamber 112a bubble-free in downstream side, detection pipe.
Venous side fixture 112c is configured compared with venous side air-foam detector 112b in downstream side.Venous side fixture 112c root
It is controlled according to the bubble testing result of venous side air-foam detector 112b, makes the passage opening/closing of venous side pipeline 112.
Venous side interconnecting piece 112d configures the another side in venous side pipeline.Venous side interconnecting piece 112d is suffering from puncture
Needle connection in person's blood vessel.
Tapping line 113 is connect with drip chamber 112a.On tapping line 113, tapping line fixture 113a is configured.Row
Liquid pipe line 113 is in the aftermentioned pipeline for starting discharge in filling process and starting servicing fluids.
Haemodialyser 120 has the container body 121 for being formed as tubular and is housed in saturating inside the container body 121
It analyses film (not shown).As haemodialyser 120, dialyzer, hemodialysis filter are used.The inside of container body 121 by
Dialysis membrane is divided into blood effluent road and dialysis fluid side flow path (not shown).Container body 121 is formed with and blood circuit
The blood introducing port 122a and blood export mouth 122b of 110A connection and the dialyzate introducing port being connected to dialysis fluid circuit 130
123a and dialyzate export mouth 123b.
According to above blood circuit 110A and haemodialyser 120, taken out from the artery of object (dialysis patient)
Blood is circulated in arterial side pipeline 111 using blood pump 111a, and is imported into the blood effluent road of haemodialyser 120.
Import haemodialyser 120 in blood utilize via the dialyzate that dialysis membrane circulates in aftermentioned dialysis fluid circuit 130 and
It is cleaned.The blood purified in haemodialyser 120 circulates in venous side pipeline 112 and the vein of returning an object value person.
Dialysis fluid circuit 130 is made of the dialysis fluid circuit 130 of so-called sealed container control mode in the present embodiment.
The dialysis fluid circuit 130 have dialyzate supply pipeline 131a, dialyzate tapping line 131b, dialyzate import pipeline 132a,
Dialyzate derivation pipeline 132b and dialyzate liquor charging portion 133.
Dialyzate liquor charging portion 133 has dialysis fluid chamber 1331, bypass line 1332 and water removal/reverse filtration pump 1333.
Dialysis fluid chamber 1331 is by that can accommodate the rigid container structure of the dialyzate of constant volume (such as 300ml~500ml)
At the inside of the container is divided into liquor charging receiving portion 1331a and drain receiving portion 1331b by soft diaphragm (diaphragm).
Bypass line 1332 connects dialyzate derivation pipeline 132b and dialyzate tapping line 131b.
Water removal/1333 configuration of reverse filtration pump is in bypass line 1332.Water removal/reverse filtration pump 1333 is by can will be other
Dialyzate inside stylet 1332 is along the direction (water removal direction) led to dialyzate tapping line 131b effluent and to dialyzate
The pump that derivation pipeline 132b effluent logical direction (reverse filtration direction) drives to liquor charging is constituted.
The base end side of dialyzate supply pipeline 131a is connect with dialysate supply unit (not shown), front end side and dialyzate
Room 1331 connects.Dialyzate supply pipeline 131a supplies dialyzate to the liquor charging receiving portion 1331a of dialysis fluid chamber 1331.
Dialyzate imports the dialyzate introducing port 123a of pipeline 132a connection dialysis fluid chamber 1331 and haemodialyser 120,
The dialyzate being housed in the liquor charging receiving portion 1331a of dialysis fluid chamber 1331 is imported to the dialyzate effluent of haemodialyser 120
Road.
The dialyzate export 123b and dialysis fluid chamber 1331 of dialyzate derivation pipeline 132b connection haemodialyser 120, will
It is exported from the dialyzate that haemodialyser 120 is discharged to the drain receiving portion 1331b of dialysis fluid chamber 1331.
The base end side of dialyzate tapping line 131b is connect with dialysis fluid chamber 1331, will be housed in drain receiving portion 1331b
In dialyzate drain discharge.
According to above dialysis fluid circuit 130, by the way that dialysis fluid chamber 1331 will be constituted using soft diaphragm (diaphragm)
The inside of rigid container demarcate, capable of making the derived quantity of the dialyzate from dialysis fluid chamber 1331, (dialyzate is received to liquor charging
The supply amount of appearance portion 1331a) it is identical as the amount of drain being recovered in dialysis fluid chamber 1331 (drain receiving portion 1331b).
Thereby, it is possible to make to import to haemodialyser 120 in the state of stopped water removal/reverse filtration pump 1333
Dialyzate flow it is equal with the amount of dialyzate (drain) derived from the haemodialyser 120.
In addition, in the case where driving water removal/reverse filtration pump 1333 in a manner of to reverse filtration direction liquor charging, from
The a part for the drain that dialysis fluid chamber 1331 is discharged is recovered to again via bypass line 1332 and dialyzate derivation pipeline 132b
In dialysis fluid chamber 1331.It therefore, is from being recovered in dialysis fluid chamber 1331 from the amount of dialyzate derived from haemodialyser 120
Amount (amount of the dialyzate to circulate in pipeline 132a is imported in dialyzate) cuts the dialyzate to circulate in bypass line 1332
The amount measured.It is saturating from blood as a result, in the flow that dialyzate imports the dialyzate to circulate in pipeline 132a
The amount of dialyzate derived from parser 120 reduces the dialyzate being recovered to again in dialysis fluid chamber 1331 via bypass line 1332
The amount of (drain).That is, in the case where driving water removal/reverse filtration pump 1333 in a manner of to reverse filtration direction liquor charging,
In haemodialyser 120, to the dialyzate of blood circuit 110A injection (reverse filtration) specified amount.
On the other hand, in the case where driving water removal/reverse filtration pump 1333 in a manner of to water removal direction liquor charging, In
The amount of the dialyzate to circulate in dialyzate derivation pipeline 132b is the amount for the dialyzate being recovered in dialysis fluid chamber 1331 (i.e. saturating
Analysis liquid imports the amount of dialyzate to circulate in pipeline 132a) measuring plus the dialyzate to circulate in bypass line 1332
Amount.As a result, in the amount that dialyzate imports the dialyzate to circulate in pipeline 132a, in dialyzate derivation pipeline 132b
The amount of the dialyzate of middle circulation increases the dialyzate (row being discharged in dialyzate tapping line 131b via bypass line 1332
Liquid) amount.That is, in the case where driving water removal/reverse filtration pump 1333 in a manner of to water removal direction liquor charging, it is saturating in blood
In parser 120, the water of specified amount is removed from blood.
Replenisher pipeline 140 is the pipeline for directly supplying dialyzate to blood circuit 110A.As shown in Figure 1, mending
The upstream side of filling liquid pipeline 140 be connected to dialysis fluid circuit 130 dialyzate import pipeline 132a in dialysis fluid chamber 1331 with
Between dialyzate introducing port 123a.It is shown in solid such as Fig. 1, arterial side pipeline is connected in the downstream side of replenisher pipeline 140
The blood filtration of dilution mode is dialysed (referring to figure before being in the case where between blood pump 111a in 111 and haemodialyser 120
4A).In addition, as indicated by the dashed line in figure 1, the drip chamber 112a in the downstream side of replenisher pipeline 140 and venous side pipeline 112
The blood filtration that mode is diluted after being in the case where connection dialyses (B referring to fig. 4).
Control device 150 as decision maker is made of information processing unit (computer), have pump work portion 151,
Bubble test section 152, fixture work department 153, determination unit 154, configuration part 155 and notification unit 156.
Pump work portion 151 is to the various pumps configured in blood circuit 110A, dialysis fluid circuit 130 and replenisher pipeline 140
Work controlled.
Bubble test section 152 makes arterial side air-foam detector 111b and venous side air-foam detector 112b respectively as needed
Work is to carry out bubble detection and obtain testing result.
Work of the fixture work department 153 according to various pumps, the bubble testing result based on bubble test section 152 are come in blood
The work (opening and closing) of the nipper configured in liquid circuit 110A, dialysis fluid circuit 130 and replenisher pipeline 140 is controlled.
In the determination method of aftermentioned detailed description, determination unit 154 is based on the bubble detection obtained by bubble test section 152
As a result, determining that replenisher pipeline 140 is to connect with arterial side pipeline 111 or connect with venous side pipeline 112.
Configuration part 155 sets feeding method of the replenisher to blood circuit 110A liquor charging.Specifically, setting is to patient's reality
The hemodialysis applied is preceding dilution mode or rear dilution mode.
Notification unit 156 is in the feeding method set by configuration part 155 and the replenisher pipeline determined by determination unit 154
It is reported in 140 situations not corresponding with the connection status of blood circuit 110A.
The control program of control device 150 described above each process by performing the following instructions, and to haemodialysis
The work of device 100A is controlled and is allowed to run.
So-called each process refers to and is cleaned as to blood circuit 110A, haemodialyser 120 to be allowed to purifying
The starting of preparatory process makes the blood of patient be filled into blood circuit 110A and recycle it in vitro after filling process, puncture
Collapse due to massive hemorrhage process, carry out after collapse due to massive hemorrhage process and dialysis process of the dialysis to be purified carried out to blood, is controlled in dialysis
The rapidly fluid infusion process of progress and blood in blood circuit 110A is made to return to returning for patient's body when blood pressure is low in treatment etc.
Blood process etc..
In the present invention, make each circuit, each connection and in the starting filling process that carries out after being assembled into circuit, sentence
Whether fixed and blood circuit 110A connection replenisher pipeline 140 is in connection status corresponding with feeding method.In connection shape
In state situation not corresponding with feeding method, circuit is reconnected, completes to start filling process with correct connection status.So
Afterwards, by collapse due to massive hemorrhage process, in dialysis process, the feeding method by way of preceding dilution or rear dilution is on one side to blood circuit
110A conveying replenisher carries out blood reverse filtration dialysis on one side.
Next, illustrating the determination method of the 1st embodiment referring to Fig. 3 and Fig. 4.Fig. 3 is to show sentencing for the 1st embodiment
Determine the figure of the flow chart of method, the circuit connection status before Fig. 4 A is shown in dilution mode, after Fig. 4 B is shown in dilution mode
Circuit connection status.
As shown in fig. 4 a and fig. 4b, the determination method of present embodiment connect arterial side interconnecting piece 111d with venous side
Portion 112d connection and carry out in the case where starting filling being preferred.In this case, servicing fluids are started by from tapping line 113
Discharge.
Before starting filling process and starting, feeding method is set in configuration part 155 in advance.As shown in fig. 4 a and fig. 4b, will
Arterial side interconnecting piece 111d is connect with venous side interconnecting piece 112d, by tapping line fixture 113a, arterial side fixture 111c, quiet
Arteries and veins side fixture 112c and replenisher pipeline are set as open state with fixture 140b.Due to be start filling process start before,
It is the state for starting servicing fluids underfill in blood circuit 110A and being filled with air.In this state, Fig. 3 is started based on
Shown in determination method judgement and carry out start filling process.
Determine that the step S10A after starting is to make water removal/reverse filtration pump 1333, fluid infusion pump 140a by pump work portion 151
And the pump work process of blood pump 111a work.By making pump work in step S10A, thus from replenisher pipeline 140 to blood
Liquid circuit 110A is conveyed using defined liquor charging amount (for example, 50mL/min) starts servicing fluids as replenisher (dialyzate), carries out
The starting of replenisher pipeline 140 fills.
In the present embodiment, as an example, make blood pump 111a in arterial side pipeline 111 to arterial side interconnecting piece
The mode of the side 111d liquor charging works (A and 4B referring to fig. 4).
Step S20A is that bubble detects process, the time point the work from various pumps after the 1st time,
Air-foam detector is set to work to detect the presence of bubble by bubble test section 152.
Here, the 1st time be set as the starting servicing fluids conveyed from replenisher pipeline 140 to blood circuit 110A not via
Haemodialyser 120 and reach air-foam detector time, with start servicing fluids via haemodialyser 120 reach bubble detection
Time between the time of device.That is, passing through time point about the 1st time, with the connection status according to circuit by bubble
The different mode of the bubble testing result that detector obtains suitably set for the 1st time.When in the present embodiment, by the 1st
Between be set as 10 seconds.
In addition, starting servicing fluids in arterial side pipeline 111 from 120 side of haemodialyser to the side arterial side interconnecting piece 111d
Liquor charging, therefore arterial side air-foam detector 111b is first reached compared with venous side air-foam detector 112b.As a result, in the situation
Under, using preferably as air-foam detector can be set to for the 1st time shorter arterial side air-foam detector 111b.Make blood
, it is preferable to use venous side air-foam detector 112b is as air-foam detector, because of energy in the case that liquid pump 111a opposite direction works
Enough the 1st time of venous side air-foam detector 112b is set to shorter.
Step S30A is to be based on bubble testing result using determination unit 154 to determine replenisher pipeline 140 and blood circuit
The judgment process of the connection status of 110A.
In the present embodiment, blood pump 111a in arterial side pipeline 111 to the side arterial side interconnecting piece 111d liquor charging
Mode work, therefore in air-foam detector, as shown in Figure 4 A, connect in replenisher pipeline 140 with arterial side pipeline 111
In the case of, pass through time point in the 1st time, starts servicing fluids and have arrived at arterial side air-foam detector 111b, gas is not detected
Bubble.On the other hand, as shown in Figure 4 B, in the case where replenisher pipeline 140 is connect with venous side pipeline 112, passed through in the 1st time
Time point is spent, servicing fluids is started and does not reach arterial side air-foam detector 111b, therefore detect bubble.Detecting gas as a result,
In the case where bubble, it is determined as that replenisher pipeline 140 is connect with venous side pipeline 112, in the case where bubble is not detected, determines
It is connect for replenisher pipeline 140 with arterial side pipeline 111.
In step s 40, control device 150 judges that the feeding method set by configuration part 155 determines with by determination unit 154
Whether connection status out corresponds to.Terminate to determine under corresponding situation (YES), in not corresponding situation (no), in step
It is reported in S50 and terminates to determine.
In the present embodiment, as shown in table 1 about the condition reported by notification unit 156.
[table 1]
After judgement and in the correct situation of connection status, filling the starting of replenisher pipeline 140 terminates.It is connecting
In the case where status error, stop the movement of various pumps, replenisher pipeline 140 is correctly being connect it with blood circuit 110A
Afterwards, the starting filling of replenisher pipeline 140 is carried out again.After the starting of replenisher pipeline 140 filling, as shown in Figure 5
Make various pump works, carries out the starting filling of blood circuit 110A, tied under correct connection status corresponding with feeding method
Do up dynamic filling process.
Determination method from the description above, by carrying out starting filling to blood circuit 110A in starting filling process
The preceding starting filling for carrying out replenisher pipeline 140, so as to determine company that replenisher pipeline 140 is connect with blood circuit 110A
Connect state.
According to the blood of the determination method and decision maker (control device 150) that have the 1st embodiment described above
Dialysis apparatus 100A can obtain following effect.
(1) one end (arterial side interconnecting piece 111d) of arterial side pipeline 111 is (quiet with the one end of venous side pipeline 112
Arteries and veins side interconnecting piece 112d) connection, in the blood circuit 110A of the state of underfill liquid, pump work portion 151, which executes, makes blood
The pump work process for pumping 111a and fluid infusion pump 140a work, makes replenisher flow into blood circuit 110A, gas from replenisher pipeline 140
Test section 152 is steeped in the state of after the 1st time, and the bubble of detection bubble is executed by air-foam detector 111b or 112b
Process is detected, determination unit 154 executes according to whether detecting bubble to determine the company of replenisher pipeline 140 Yu blood circuit 110A
Connect the judgment process of state.Thereby, it is possible to fill process using the starting in haemodialysis equipment 100A, supplement is simply determined
The connection status of liquid pipe line 140 and blood circuit 110A.
(2) the connecting portion phase with replenisher pipeline 140 being configured at air-foam detector 111b in arterial side pipeline 111
Than the position for more leaning on one end, pump work portion 151 makes blood pump 111a in pump work process so that replenisher is towards arterial side
The mode of the one end flowing of pipeline 111 works, and determination unit 154, in the case where bubble is not detected, is sentenced in judgment process
It is set to replenisher pipeline 140 to connect with venous side pipeline 112, replenisher pipeline 140 is determined as in the case where detecting bubble
It is connect with venous side pipeline 112.The one end of replenisher towards arterial side pipeline 111 flows as a result, therefore and air-foam detector
Configuration is compared in the case where venous side pipeline 112, can shorten the 1st time in bubble detection process.Thereby, it is possible to shorter
Time is attached the judgement of state.
(3) decision maker (control device 150) is also equipped with: configuration part 155, sets replenisher to blood circuit 110A's
Feeding method;And notification unit 156, in the feeding method set by configuration part 155 and the connection determined by determination unit 154
It is reported in the not corresponding situation of state.As a result, in the connection status mistake of replenisher pipeline 140 and blood circuit 110A
In the case of, it can quickly report medical personnel located.
<variation>
Next, illustrating the variation of the 1st embodiment referring to Fig. 6.
In the determination method of variation, whether bubble inspection is reached until the 1st time passed through according to starting servicing fluids
It surveys device and is attached state judgement.Other than the time point of beginning bubble detection is different from the 1st embodiment, with haemodialysis
The composition of device 100A is identical, and and the description is omitted.
In a same manner as in the first embodiment, liquor charging side is preset for configuration part 155 before starting filling process and starting
Method.As shown in fig. 4 a and fig. 4b, arterial side interconnecting piece 111d is connect with venous side interconnecting piece 112d, by tapping line fixture
113a, arterial side fixture 111c, venous side fixture 112c and replenisher pipeline are set as open state with fixture 140b.Due to being to start
Before filling process starts, therefore for underfill starts servicing fluids and fills in blood circuit 110A and in replenisher pipeline 140
There is the state of air.In this state, start to carry out the judgement based on determination method shown in fig. 6 and execute starting filling work
Sequence.
Determine that the step S10A after starting is to make water removal/reverse filtration pump 1333, fluid infusion pump 140a by pump work portion 151
And the pump work process of blood pump 111a work.By replenisher (dialyzate) as servicing fluids are started, with defined liquor charging amount (example
Such as, 50mL/min) from from replenisher pipeline 140 to blood circuit 110A liquor charging, the starting thereby executing replenisher pipeline 140 adds
Note.
Step S20A ' is so that air-foam detector is worked to examine by bubble test section 152 after the work of various pumps starts
Survey bubble whether there is or not bubble detect process.Bubble testing result is, is being until starting servicing fluids and reaching air-foam detector
There is bubble, is bubble-free after starting servicing fluids and reaching.
Step S30A ' is to start servicing fluids until by the 1st time according to from pump work by determination unit 154
Whether reach air-foam detector, whether detect bubble no longer to determine the company of replenisher pipeline 140 Yu blood circuit 110A
Connect the judgment process of state.Here, the 1st time can with 1 embodiment the case where in the same manner as set.
In variation, blood pump 111a in arterial side pipeline 111 to the side of the side arterial side interconnecting piece 111d liquor charging
Formula work, therefore in air-foam detector, the case where replenisher pipeline 140 as shown in Figure 4 A is connect with arterial side pipeline 111
Under, servicing fluids are started in the 1st time and have arrived at arterial side air-foam detector 111b by time point, and bubble is not detected.Separately
On the one hand, in the case where replenisher pipeline 140 as shown in Figure 4 B is connect with venous side pipeline 112, servicing fluids are started at the 1st
Between do not reach arterial side air-foam detector 111b by time point, therefore detect bubble.As a result, until the 1st time process
Until start servicing fluids and reach and no longer detect under the condition of bubble, be determined as that replenisher pipeline 140 and arterial side pipeline 111 connect
It connects, in the case where also not up to detecting bubble even across the 1st time starting servicing fluids, is determined as replenisher pipeline
140 connect with venous side pipeline 112.
In step s 40, control device 150 judges that the feeding method set by configuration part 155 determines with by determination unit 154
Whether connection status out corresponds to.Terminate to determine under corresponding situation (YES), in step S50 in not corresponding situation (no)
In reported by notification unit 156 and terminate to determine.
It is as shown in table 2 about the condition reported by notification unit 156 in variation.
[table 2]
After judgement and in the case where connection status mistake, stops the movement of various pumps, make replenisher pipeline 140
The starting filling of replenisher pipeline 140 is carried out after correctly connecting with blood circuit 110A again.In the starting of replenisher pipeline 140
After filling, the starting filling of blood circuit 110A is carried out.Specifically, as shown in figure 5, being set as making arterial side fixture
The shape that 111c, venous side fixture 112c and tapping line are out with fixture 113a and close replenisher pipeline with fixture 140b
State.Make various pump works as shown in Figure 5 by pump work portion 151, so that dialyzate is injected haemodialyser by reverse filtration
120, execute the starting filling of blood circuit 110A.
Make various pump works in the manner described above to carry out the starting of blood circuit 110A filling, with corresponding with feeding method
Correct connection status complete start filling process.
Determination method from the description above is held before carrying out starting filling to blood circuit 110A in starting filling process
The starting of row replenisher pipeline 140 fills, the presence or absence of the bubble detection after the 1st time of confirmation warp, so as to determine to supplement
The connection status of liquid pipe line 140 and blood circuit 110A.
It is filled according to the haemodialysis for the determination method and decision maker (control device 150) for having variation described above
100A is set, is had and said effect (1)~(3) identical effect.
<the 2nd embodiment>
Illustrate the 2nd embodiment referring next to Fig. 7~Figure 11.
Illustrate the overall structure of the haemodialysis equipment 100B of the 2nd embodiment referring to Fig. 7 and Fig. 8.Fig. 7 is to show this hair
The figure of the schematic configuration of haemodialysis equipment 100B in bright 2nd embodiment, Fig. 8 are to show haemodialysis equipment 100B
Block diagram.
2nd embodiment is different from the haemodialysis equipment 100A of the 1st embodiment in the following areas: haemodialysis equipment
Blood circuit 110B in 100B does not have drain pipeline and has ventilation line 114, and in addition haemodialysis equipment 100B has
There is liquid level adjustment pump 114b.Other are constituted and marks identical appended drawing reference and omits the description.
As shown in Figures 7 and 8, haemodialysis equipment 100B has blood circuit 110B, the blood for making blood flow
Pump 111a, arterial side air-foam detector 111b, venous side air-foam detector 112b, haemodialyser 120, dialysis fluid circuit 130,
Dialyzate liquor charging portion 133, replenisher pipeline 140, fluid infusion pump 140a, the control device 150 as decision maker, liquid level adjustment pump
114b。
Blood circuit 110B has arterial side pipeline 111, venous side pipeline 112, ventilation line 114.
The one end of venous side pipeline 112 is connect with the blood export mouth 122b of haemodialyser 120.Venous side pipeline
112 are configured with drip chamber 112a, venous side air-foam detector 112b, venous side fixture 112c and venous side interconnecting piece 112d.
Drip chamber 112a accumulates certain to remove the bubble being mixed into venous side pipeline 112, cakey blood etc.
The blood of amount.
Venous side air-foam detector 112b is configured compared with drip chamber 112a bubble-free in downstream side, detection pipe.
Venous side fixture 112c configuration is in the position of side farther downstream compared with venous side air-foam detector 112b.Venous side
Fixture 112c is controlled according to the bubble testing result of venous side air-foam detector 112b, makes the flow path of venous side pipeline 112
Opening and closing.
Venous side interconnecting piece 112d configures the another side in venous side pipeline.Venous side interconnecting piece 112d is suffering from puncture
Needle connection in person's blood vessel.
Ventilation line 114 is the pipe being arranged for making the air inflow and outflow in drip chamber 112a, one end and drip chamber
The top of 112a connects.Ventilation line 114 is configured with ventilation line fixture 114a, and the ventilation line is with fixture 114a by electromagnetism
Valve constitutes, makes the passage opening/closing of ventilation line 114.In addition, the another side in ventilation line 114 is pumped configured with liquid level adjustment
114b is used to pass air into outflow drip chamber 112a, to be adjusted the liquid level of liquid.
According to above blood circuit 110B and haemodialyser 120, taken out from the artery of object (dialysis patient)
Blood circulated in arterial side pipeline 111 using blood pump 111a, and led to the blood effluent road of haemodialyser 120
Enter.The blood for being directed into haemodialyser 120 utilizes the dialyzate to circulate in aftermentioned dialysis fluid circuit 130 via dialysis membrane
And it is cleaned.The blood being cleaned in haemodialyser 120 circulates in venous side pipeline 112, and returning an object value person's is quiet
Arteries and veins.
Illustrate the determination method of the 2nd embodiment referring next to Fig. 9~Figure 11.Fig. 9 is to show sentencing for the 2nd embodiment
Determine the figure of the flow chart of method, Figure 10 is to execute saying for the case where starting filling to blood circuit 110B in starting filling process
Bright figure.The connection status in the circuit before Figure 11 A is shown in dilution mode, the connection in the circuit after Figure 11 B is shown in dilution mode
State.
The determination method of present embodiment is as shown in Figures 10 and 11, connects arterial side interconnecting piece 111d and venous side
Socket part 112d connection and execute start filling in the case where be preferred.In this case, servicing fluids are started respectively by from artery
Side interconnecting piece 111d and venous side interconnecting piece 112d discharge.
In addition, executing starting to blood circuit 110B in advance before determining to start in the determination method of present embodiment
Filling, into blood circuit 110B, filling starts servicing fluids (reverse filtration dialyzate) and does not fill to replenisher pipeline 140
In the state of dynamic servicing fluids (dialyzate as replenisher) (being filled with gas), it is attached the judgement of state.
As shown in Figure 10, it is set as making arterial side fixture 111c, venous side fixture 112c and ventilation line fixture 114a
The state opened and close replenisher pipeline with fixture 140b.As shown in Figure 10, make various pump works using pump work portion 151,
Dialyzate is set to inject haemodialyser 120 from dialysis fluid circuit 130 using reverse filtration, the starting for executing blood circuit 110B adds
Note.Filled in the starting for being not carried out replenisher pipeline 140 and in replenisher pipeline 140 filled with air in the state of carry out with
The judgement of the connection status of lower explanation.In addition, the liquid level of drip chamber 112a leads in the starting filling of blood circuit 110B
It crosses liquid level adjustment pump 114b and is adjusted to defined liquid level.Then, make ventilation line fixture using fixture work department 153
114a works and is set as closed state, to keep liquid level.
Before determining to start, feeding method is preset by configuration part 155.
As shown in figure 9, determining that the step S10B after starting is following such pump work processes: making arterial side fixture
The state that 111c, venous side fixture 112c and replenisher pipeline are out with fixture 140b and close ventilation line with fixture 114a
Under, so that water removal/reverse filtration pump 1333, fluid infusion is pumped 140a and blood pump 111a and is worked by pump work portion 151.Utilize pump work
Portion 151 makes various pump works as shown in Figure 11 A and 11B, injects dialyzate with the flow of 350mL/min using reverse filtration
Haemodialyser 120 send replenisher (dialyzate) to blood circuit 110B from replenisher pipeline 140 with the flow of 50mL/min
Liquid.In addition, blood pump 111a works according in such a way that the flow of 200mL/min is to the side arterial side interconnecting piece 111d liquor charging.By
This, is started servicing fluids (reverse filtration dialyzate, replenisher) and is arranged with the flow of 200mL/min from arterial side interconnecting piece 111d
Out, it is in addition discharged with the flow of 200mL/min from venous side interconnecting piece 112d.
For the liquor charging amount of various pumps, set in the following manner, that is, in replenisher pipeline 140 and arterial side
In the case that pipeline 111 connects, a part for the air being filled in replenisher pipeline 140 first reaches arterial side air-foam detector
111b, other parts then reach venous side air-foam detector 112b by haemodialyser 120;In addition, being in the following manner
It can, that is, in the case where replenisher pipeline 140 is connect with venous side pipeline 112, a part of air first reaches venous side bubble
Detector 112b, other parts then reach arterial side air-foam detector 111b by haemodialyser 120.
In the present embodiment, fluid infusion pump 140a liquor charging amount be set as fewer than the liquor charging amount of blood pump 111a, and than from
To subtract the amount that the liquor charging amount of blood pump 111a obtains in the injection rate of the dialyzate of reverse filtration injection haemodialyser 120
It is few.The air of blood circuit 110B is delivered to from replenisher pipeline 140 as a result, in the case where not passing through haemodialyser 120
The one party being transported in arterial side air-foam detector 111b and venous side air-foam detector 112b.
Step S20B is to be made after the movement of the various pumps based on pump work portion 151 starts by bubble test section 152
Arteries and veins side air-foam detector 111b and venous side air-foam detector 112b work detect the bubble inspection of bubble to start bubble detection
Survey process.
As shown in Figure 11 A, in the case where replenisher pipeline 140 is connect with arterial side pipeline 111, it is filled in supplement liquid pipe
Air in line 140 reaches arterial side air-foam detector 111b and is detected.In addition, as shown in Figure 11 B, in replenisher pipeline
In the case that 140 connect with venous side pipeline 112, the air being filled in replenisher pipeline 140 reaches the detection of venous side bubble
Device 112b and be detected.
Step S30B is to determine replenisher pipeline 140 to blood circuit based on bubble testing result by determination unit 154
The judgment process of the connection status of 110B.
Determination unit 154 is first passing through arterial side air-foam detector after having started bubble detection by bubble test section 152
111b and in the case where detecting bubble, be determined as that replenisher pipeline 140 is connect with arterial side pipeline 111, first passing through vein
Side air-foam detector 112b and in the case where detecting bubble, be determined as that replenisher pipeline 140 is connect with venous side pipeline 112.
In step s 40, control device 150 judges that the feeding method set by configuration part 155 determines with by determination unit 154
Whether connection status out corresponds to.Terminate to determine in corresponding situation (YES), in not corresponding situation (no), in step S50
In reported and terminate to determine.
In the present embodiment, as shown in table 3 about the condition reported by notification unit 156.
[table 3]
After judgement, in the correct situation of connection status, starting filling is continued to execute, from blood circuit 110B and benefit
Air is removed in filling liquid pipeline 140 and completes to start filling process.In the case where connection status mistake, make the work of various pumps
Stop and after correctly connect replenisher pipeline 140 with blood circuit 110B, again progress replenisher pipeline 140 and blood time
The starting of road 110B fills, and completes to start filling process under correct connection status corresponding with feeding method.
Determination method from the description above starts filling executing to blood circuit 110B in starting filling process
And in the state of being full of by starting servicing fluids, the replenisher pipeline 140 filled with air is executed and starts filling, in artery side pipe
Bubble detection is carried out in line 111 and venous side pipeline 112, so as to determine replenisher pipeline 140 to blood circuit 110B's
Connection status.
According to the blood of the determination method and decision maker (control device 150) that have the 2nd embodiment described above
Dialysis apparatus 100B can obtain following effect.
(4) in the state that blood circuit 110B is filled with gas is filled in liquid and replenisher pipeline 140, pump work
Portion 151 executes pump work process, that is, carries out reverse filtration to dialyzate on one side and it is injected blood from dialysis fluid circuit 130
Dialyzer 120 flows liquid to the one end of arterial side pipeline 111 on one side with the few flow of the injection rate than dialyzate, presses
So that blood pump 111a is worked according to this mode and make fluid infusion pump 140a work, by pump work portion 151 make blood pump 111a and
After fluid infusion pumps 140a work, the execution of bubble test section 152 starts based on arterial side air-foam detector 111b and the inspection of venous side bubble
The bubble detection for surveying device 112b detects process to detect the bubble of bubble, and determination unit 154 executes judgment process, that is, is first passing through
The arterial side air-foam detector 111b and in the case where detecting bubble, be determined as replenisher pipeline 140 and arterial side pipeline 111
Connection, in the case where first passing through venous side air-foam detector 112b and detect bubble, be determined as replenisher pipeline 140 with it is quiet
Arteries and veins side pipe line 112 connects.Thus, it is possible to use the starting in haemodialysis equipment 100B to fill process, replenisher is simply determined
Connection status of the pipeline 140 to blood circuit 110B.
(5) liquor charging amount of fluid infusion pump 140a is made to be less than the liquor charging amount of blood pump 111a, and less than the injection rate from dialyzate
Subtract the amount that the liquor charging amount of blood pump 111a obtains.Exist as a result, from the air that replenisher pipeline 140 is delivered to blood circuit 110B
Not by being transported to arterial side air-foam detector 111b and venous side air-foam detector 112b in the case where haemodialyser 120
In one party.
(6) decision maker (control device 150) also includes configuration part 155, sets replenisher to blood circuit 110B's
Feeding method;And notification unit 156, the feeding method set by configuration part 155 are determined with by the determination unit 154
It is reported in the not corresponding situation of connection status.It is wrong in connection status of the replenisher pipeline 140 to blood circuit 110B as a result,
In the case where accidentally, medical personnel located can be quickly reported.
The preferred each embodiment and variation of determination method to connection status of the invention and decision maker above
It is illustrated, but the present invention is not limited to the respective embodiments described above and variations, can suitably change.
For example, in the 1st embodiment and variation, as an example, with from haemodialyser side in arterial side pipeline
Make blood pump work to the mode of arterial side interconnecting piece side liquor charging, in the state of after the 1st time, passes through arterial side bubble
The presence or absence of detector detection bubble (starting whether servicing fluids reach), but not limited to this.It is also possible to make in arterial side pipeline
Blood pump works in a manner of from arterial side interconnecting piece side to haemodialyser side liquor charging, or can also pass through the venous side gas
The presence or absence of bubble detector detection bubble (starting whether servicing fluids reach).
In addition, in the 2nd embodiment, in pump work process, according to one side to dialyzate carry out reverse filtration and from
Its dialysis fluid circuit 130 is injected into haemodialyser 120, makes liquid on one side to be less than the flow of the injection rate of dialyzate to artery
The mode of the one end flowing of side pipe line 111 makes blood pump 111a work and makes fluid infusion pump 140a work, but not limited to this.That is,
It can also implement pump work process in the case where not making blood pump work.
Description of symbols
100A, 100B haemodialysis equipment
110A, 110B blood circuit
111 arterial side pipelines
111a blood pump
111b arterial side air-foam detector
111d arterial side interconnecting piece
112 venous side pipelines
112b venous side air-foam detector
112d venous side interconnecting piece
120 haemodialysers
130 dialysis fluid circuits
131a dialyzate supply pipeline
131b dialyzate tapping line
132a dialyzate imports pipeline
132b dialyzate derivation pipeline
133 dialyzate liquor charging portions
1331 dialysis fluid chambers
1332 bypass lines
1333 water removals/reverse filtration pump
140 replenisher pipelines
140a fluid infusion pump
150A, 150B control device (decision maker)
151 pump work portions
152 bubble test sections
153 fixture work departments
154 determination units
155 configuration parts
156 notification units
Claims (12)
1. the determination method of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment, the haemodialysis equipment
Have:
Haemodialyser;
Blood circuit, with the connection of the artery of one end and object and what another side was connect with the haemodialyser moves
Arteries and veins side pipe line and one end are connect with the haemodialyser and the vein side pipe of the Connect of Vein of another side and object
Line;
Blood pump is configured in the arterial side pipeline;
Dialysis fluid circuit, have to the haemodialyser import dialyzate dialyzate import pipeline and from the blood it is saturating
The dialyzate derivation pipeline of parser export dialyzate;
Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, Xiang Suoshu blood circuit conveying supplement
Liquid;
Fluid infusion pump, configures in the replenisher pipeline;And
Air-foam detector is configured in the arterial side pipeline or the venous side pipeline, is detected to bubble,
The determination method includes:
Pump work process, wherein connect in the one end of the arterial side pipeline with the one end of the venous side pipeline and not
In the blood circuit of hydraulically full state, make the blood pump and the fluid infusion pump work;
Bubble detects process, wherein after making the blood pump and the fluid infusion pump work, when by the preset 1st
Between after in the state of, utilize the air-foam detector carry out bubble detection;And
Judgment process, wherein whether bubble is detected according to using the air-foam detector, to determine the replenisher pipeline
It is to connect with the arterial side pipeline or connect with the venous side pipeline.
2. determination method according to claim 1, wherein
The air-foam detector configures more leaning in the arterial side pipeline compared with the connecting portion of the replenisher pipeline
The position of one end,
In the pump work process, make the blood in such a way that the one end for making replenisher towards the arterial side pipeline flows
Liquid pump work,
In the judgment process, the replenisher pipeline and the artery side pipe are determined as in the case where bubble is not detected
Line connection, is determined as that the replenisher pipeline is connect with the venous side pipeline in the case where detecting bubble.
3. the decision maker of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment, the haemodialysis equipment
Have:
Haemodialyser;
The blood circuit, with the connection of the artery of one end and object and another side is connect with the haemodialyser
Arterial side pipeline and one end is connect with the haemodialyser and the venous side of the Connect of Vein of another side and object
Pipeline;
Blood pump is configured in the arterial side pipeline;
Dialysis fluid circuit, have to the haemodialyser import dialyzate dialyzate import pipeline and from the blood it is saturating
The dialyzate derivation pipeline of parser export dialyzate;
Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, Xiang Suoshu blood circuit conveying supplement
Liquid;
Fluid infusion pump, configures in the replenisher pipeline;And
Air-foam detector is configured in the arterial side pipeline or the venous side pipeline, is detected to bubble,
The decision maker has:
Pump work portion is connect and underfill in the one end of the arterial side pipeline with the one end of the venous side pipeline
In the blood circuit of the state of liquid, make the blood pump and the fluid infusion pump work;
Bubble test section, after making the blood pump and the fluid infusion pump work using the pump work portion, by preparatory
In the state of after 1st time of setting, bubble detection is carried out using the air-foam detector;And
Whether determination unit detects bubble according to using the air-foam detector, come determine the replenisher pipeline be with
The arterial side pipeline connection is still connect with the venous side pipeline.
4. decision maker according to claim 3, wherein
The air-foam detector is configured in the arterial side pipeline,
The pump work portion makes the blood pump work in such a way that the one end for making replenisher towards the arterial side pipeline flows
Make,
The determination unit is determined as that the replenisher pipeline is connect with the arterial side pipeline in the case where bubble is not detected,
It is determined as that the replenisher pipeline is connect with the venous side pipeline in the case where detecting bubble.
5. decision maker according to claim 3 or 4, is also equipped with:
Configuration part sets feeding method of the replenisher to the blood circuit;And
Notification unit is not right in the feeding method set by the configuration part and the connection status that is determined using the determination unit
It is reported in the case where answering.
6. the determination method of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment, the haemodialysis equipment
Have:
Haemodialyser;
Blood circuit, with the connection of the artery of one end and object and what another side was connect with the haemodialyser moves
Arteries and veins side pipe line and one end are connect with the haemodialyser and the vein side pipe of the Connect of Vein of another side and object
Line;
Blood pump is configured in the arterial side pipeline;
Dialysis fluid circuit, have to the haemodialyser import dialyzate dialyzate import pipeline and from the blood it is saturating
The dialyzate derivation pipeline of parser export dialyzate;
Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, Xiang Suoshu blood circuit conveying supplement
Liquid;
Fluid infusion pump, configures in the replenisher pipeline;
Arterial side air-foam detector is configured in the arterial side pipeline, is detected to bubble;And
Venous side air-foam detector is configured in the venous side pipeline, is detected to bubble,
The determination method includes:
Pump work process, wherein be filled with the state of gas filled with liquid and the replenisher pipeline in the blood circuit
Under, dialyzate reverse filtration is made on one side it inject the haemodialyser from the dialysis fluid circuit, makes the benefit on one side
Liquid pump work;
Bubble detects process, wherein after making the fluid infusion pump work, starts based on the arterial side air-foam detector and described
The bubble of venous side air-foam detector is detected to detect bubble;And
Judgment process, wherein a side in the arterial side air-foam detector or the venous side air-foam detector with it is another
Side determines the replenisher pipeline and the arterial side pipeline or the venous side pipeline compared in the case where first detecting bubble
In which side connection.
7. determination method according to claim 6, wherein
In the pump work process, the state of gas is filled with filled with liquid and the replenisher pipeline in the blood circuit
Under, so that it is injected the haemodialyser from the dialysis fluid circuit dialyzate reverse filtration according to one side, on one side with few
Make the blood pump work in the mode for the one end that the flow of the injection rate of dialyzate makes liquid flow to arterial side pipeline, and
Make the fluid infusion pump work,
In the judgment process, it is determined as in the case where first detecting bubble using the arterial side air-foam detector described
Replenisher pipeline is connect with the arterial side pipeline, in the case where first detecting bubble using the venous side air-foam detector
It is determined as that the replenisher pipeline is connect with the venous side pipeline.
8. determination method according to claim 6 or 7, wherein
The liquor charging amount of the fluid infusion pump is less than the liquor charging amount of the blood pump, and is less than from the injection rate of the dialyzate and subtracts institute
State the amount that the liquor charging amount of blood pump obtains.
9. the decision maker of the connection status of replenisher pipeline and blood circuit in haemodialysis equipment, the haemodialysis equipment
Have:
Haemodialyser;
Blood circuit, with the connection of the artery of one end and object and what another side was connect with the haemodialyser moves
Arteries and veins side pipe line and one end are connect with the haemodialyser and the vein side pipe of the Connect of Vein of another side and object
Line;
Blood pump is configured in the arterial side pipeline;
Dialysis fluid circuit, have to the haemodialyser import dialyzate dialyzate import pipeline and from the blood it is saturating
The dialyzate derivation pipeline of parser export dialyzate;
Replenisher pipeline is connect with the arterial side pipeline or the venous side pipeline, Xiang Suoshu blood circuit conveying supplement
Liquid;
Fluid infusion pump, configures in the replenisher pipeline;
Arterial side air-foam detector is configured in the arterial side pipeline, is detected to bubble;And
Venous side air-foam detector is configured in the venous side pipeline, is detected to bubble,
The decision maker has:
Pump work portion, in the state that the blood circuit is filled with liquid and the replenisher pipeline is filled with gas, one
While dialyzate reverse filtration is made it inject the haemodialyser from the dialysis fluid circuit, make the fluid infusion pump work on one side
Make;
Bubble test section starts based on institute after making the blood pump and the fluid infusion pump work using the pump work portion
The bubble for stating arterial side air-foam detector and the venous side air-foam detector is detected to detect bubble;And
Determination unit, the side in the arterial side air-foam detector or the venous side air-foam detector is compared with another party
In the case where first detecting bubble, which in the replenisher pipeline and the arterial side pipeline or the venous side pipeline is determined
One side connection.
10. decision maker according to claim 9, wherein
It is pressed in the state that the blood circuit is filled with liquid and the replenisher pipeline is filled with gas in the pump work portion
According on one side dialyzate reverse filtration is made its from the dialysis fluid circuit inject the haemodialyser, while with less than dialysis
The flow of the injection rate of liquid make liquid flow to arterial side pipeline one end mode, make the blood pump work, and make institute
Fluid infusion pump work is stated,
The determination unit is after starting bubble detection using the bubble test section, first using the arterial side air-foam detector
It is determined as that the replenisher pipeline is connect with the arterial side pipeline in the case where detecting bubble, is utilizing the venous side gas
Bubble detector is determined as that the replenisher pipeline is connect with the venous side pipeline in the case where first detecting bubble.
11. decision maker according to claim 9 or 10, wherein
The liquor charging amount of the fluid infusion pump is less than the liquor charging amount of the blood pump, and is less than from the injection rate of the dialyzate and subtracts institute
State the amount that the liquor charging amount of blood pump obtains.
12. the decision maker according to any one of claim 9~11, is also equipped with:
Configuration part sets feeding method of the replenisher to the blood circuit;And
Notification unit is not right in the feeding method set by the configuration part and the connection status that is determined using the determination unit
It is reported in the case where answering.
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JP2017-079826 | 2017-04-13 | ||
JP2017079826A JP6900756B2 (en) | 2017-04-13 | 2017-04-13 | Method and device for determining the connection status of the replenisher line to the blood circuit in the hemodialysis machine |
PCT/JP2018/015595 WO2018190433A1 (en) | 2017-04-13 | 2018-04-13 | Method and device for determining state of connection of liquid replenishing line to blood circuit in hemodialysis device |
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CN118142010A (en) * | 2024-05-10 | 2024-06-07 | 四川省肿瘤医院 | Intelligent detection system and method for faults of built-in system of hemodialysis instrument |
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JP7293761B2 (en) * | 2019-03-18 | 2023-06-20 | 株式会社ジェイ・エム・エス | Determining method for dialysis machine and circuit set |
JP6775056B2 (en) * | 2019-04-01 | 2020-10-28 | 日機装株式会社 | Blood purification device |
WO2021059573A1 (en) * | 2019-09-24 | 2021-04-01 | 株式会社ジェイ・エム・エス | Blood purification device |
JP2021049061A (en) * | 2019-09-24 | 2021-04-01 | 株式会社ジェイ・エム・エス | Blood purification device |
JP2023143290A (en) * | 2022-03-25 | 2023-10-06 | 株式会社ジェイ・エム・エス | Hemodialyzer including liquid supply line |
JP2024035694A (en) * | 2022-09-02 | 2024-03-14 | 澁谷工業株式会社 | Dialysis device and connection check method of fluid replacement passage |
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WO2018190433A1 (en) | 2018-10-18 |
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JP6900756B2 (en) | 2021-07-07 |
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