CN110463988A - A kind of full nutrient formulation powder of the hypotonic type of low fat and preparation method thereof - Google Patents

A kind of full nutrient formulation powder of the hypotonic type of low fat and preparation method thereof Download PDF

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Publication number
CN110463988A
CN110463988A CN201910671973.0A CN201910671973A CN110463988A CN 110463988 A CN110463988 A CN 110463988A CN 201910671973 A CN201910671973 A CN 201910671973A CN 110463988 A CN110463988 A CN 110463988A
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China
Prior art keywords
parts
vitamin
powder
low fat
nutrient formulation
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CN201910671973.0A
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Chinese (zh)
Inventor
张文杰
谢元德
斯智萍
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Zhejiang Nuclear Power Xinjian Pharmaceutical Co Ltd
Zhejiang Hejiansheng Nutrition Technology Co Ltd
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Zhejiang Nuclear Power Xinjian Pharmaceutical Co Ltd
Zhejiang Hejiansheng Nutrition Technology Co Ltd
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Priority to CN201910671973.0A priority Critical patent/CN110463988A/en
Publication of CN110463988A publication Critical patent/CN110463988A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pediatric Medicine (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses full nutrient formulation powder of the hypotonic type of a kind of low fat and preparation method thereof, a kind of full nutrient formulation powder of the hypotonic type of low fat includes the carbohydrate that weight ratio is 40~55 parts, 1~7 part of Medium chain fatty, 22~38 parts of high-quality protein, 1~5 part of L-Glutamine, 0~7 part of thickener, 0~10 part of sweetener, 0~3.5 part of edible essence, 0~2 part of emulsifier, 0~1.5 part of vitamin premixed powder, 0~2.5 part of L-carnitine, 1~1.5 part of acidity regulator, 0~1 part of Cardia Salt and 1.5~2.5 parts of minerals premixed powder, a kind of preparation method of the full nutrient formulation powder of the hypotonic type of low fat includes a) weighing;B) it crushes;C) it premixes;D) total mix and e) dispense, formula have the characteristics that low fat, high protein and Hi CHO, poor suitable for gastrointestinal function, Yi Fasheng diarrhea patient and other need the crowd of low fat, hypotonic diet.

Description

A kind of full nutrient formulation powder of the hypotonic type of low fat and preparation method thereof
[technical field]
The present invention relates to the technical field of Medical Nutritional food, the full nutrient formulation powder of the especially a kind of hypotonic type of low fat and its The technical field of preparation method.
[background technique]
With the progress of modern medicine, EN support is increasingly by the attention of medical field.EN support has Help guarantee that intestinal mucosa maintains normal secreting function, maintain gut barrier function, improve nutritional status, promotes body nitrogen flat Weighing apparatus and maintenance immunoregulation, therefore become the preferred nutritional intervention method of Critical Ill Patient.
But for patient after gastrointestinal surgery, due to the seriousness and complexity of its disease, quite a few disease There are the case where gastrointestinal tract does not tolerate, such as abdominal pain, diarrhea, abdominal distension and nausea and vomiting in regular meeting, therefore can not be according to reaching in the original plan Dosage is fed to target to reach nutrition treatment purpose.It, can direct shadow if long-term existence enteral nutrition gastrointestinal tract does not tolerate Enteron aisle normal physiological structure function is rung, function of intestinal mucosa barrier in patient is destroyed, leads to intestinal flora transposition, thus concurrent intestines source property endogenous toxic material Plain mass formed by blood stasis eventually leads to Multiple Organ Failure Syndrome MODS generation.Fat is an important factor for influencing gastrointestinal toleration. High fat diet easily causes stomach and does not tolerate, and as fat content > 20%, Incidence of Diarrhea is obviously increased.Bile acid concentration is lower than Normal critical concentration value will lead to steatorrhea, and excess fatty acids can induce organic matter and the absorption of electrolyte and reduce, and cause to seep Permeability diarrhea.Osmotic pressure is another main cause for influencing gastrointestinal toleration.If nutrient solution is hypertonicity diet, meeting Stimulation large quantity of moisture enters gastrointestinal tract with dilute solution concentration, and enterocinesia is stimulated to accelerate and diarrhea occurs.
Inflammatory bowel disease refers to the unknown enteron aisle chronic inflammation disease of reason, mainly includes Crohn disease and exedens knot Enteritis.Inflammatory bowel disease is easy to cause malnutritive, Hypoproteinemia and anaemia etc..Nutritional support treatment is inflammatory bowel disease (IBD) it is digested to have obtained state for the important component treated, the especially effect in Crohn disease (CD) treatment The extensive attention of section's medicine.The principle of nutrition treatment is to meet the nutritional need of patient, simultaneously by a variety of nutritional support modes The stimulation of intestines caused by inflammation is reduced to minimum.Extension property bowel disease, often occurs steatorrhea, at this time the rouge of malabsorption The hydroxy-acid derivative that fat acid and enteric bacteria generate, can stimulate colon secretion and aggravate symptom of diarrhea, therefore inflammatory bowel Patient should select low fat diet.
Bile is firstly stored among gall-bladder by hepatic secretion, when body dietary intake, gallbladder contraction, and bile discharge, It assists the lipolysis of bulky grain to be little particle, in order to which digestive ferment further digests.Human body is as occurred cholecystitis or gallbladder knot When the gallbladder diseases such as stone, paracholia, fatty digestion and absorption will receive influence, and fat food can promote The secretion of cholecystokinin makes gallbladder contraction, induces gallbladder pain, therefore gall-bladder class Disease is also required to low-fat nutrition food Product.
Therefore, it needs a kind of patient poor for gastrointestinal function, Yi Fasheng diarrhea and other needs the hypotonic drink of low fat The crowd of food, such as the patient of enteral nutrition is initially used after fasting, cholecystitis, gall stone, cholecystectomy, intestinal surgery are quasi- A kind of low fat of standby, patient after gastrointestinal procedures, the patient for needing low-cholesterol diet etc., hypotonic type nutrient formulation powder.
[summary of the invention]
The object of the invention is to solve the problems of the prior art, propose a kind of full nutrient formulation powder of the hypotonic type of low fat and Preparation method, formula have the characteristics that low fat, high protein and Hi CHO, and it is poor, easy to be suitable for gastrointestinal function Occur diarrhea patient and other need the crowd of low fat, hypotonic diet.
To achieve the above object, the present invention is achieved through the following technical solutions:
A kind of full nutrient formulation powder of the hypotonic type of low fat, including weight ratio be 40~55 parts carbohydrate, 1~7 part Medium chain fatty, 22~38 parts of high-quality protein, 1~5 part of L-Glutamine, 0~7 part of thickener, 0~10 part of sweet taste Agent, 0~3.5 part of edible essence, 0~2 part of emulsifier, 0~1.5 part of vitamin premixed powder, 0~2.5 part left-handed Carnitine, 1~1.5 part of acidity regulator, 0~1 part of Cardia Salt and 1.5~2.5 parts of minerals premixed powder.
Preferably, the carbohydrate is maltodextrin, the Medium chain fatty is medium chain triglyceride powder and powder The mixture of one or both of linseed oil, the high-quality protein are one in PURE WHEY and soybean separation protein white powder Kind or two kinds of mixture, the thickener are the mixture of one or both of guar gum and xanthan gum, the sweet taste Agent is crystal diabetin, and the edible essence is the mixture of one or both of vanilla and milk powder essence, described Emulsifier is soybean lecithin, and the vitamin premixed powder includes vitamin A, vitamin D, vitamin E, vitamin B1, niacin, Pantothenic acid, vitamin B6, vitamin C, taurine, vitamin B2, folic acid and vitamin B12, the vitamin A based on its parts by weight 1120~1680 parts, 2.640~3.960 parts of vitamin D, 20580~30870 parts of vitamin E, vitamin B12816~ 4224 parts, 27616~41424 parts of niacin, 7824~11736 parts of pantothenic acid, vitamin B62624~3936 parts, vitamin C 300000~450000 parts, 201600~302400 parts of taurine, vitamin B22432~3648 parts, folic acid 349.4~ 524.2 part, vitamin B125.856~8.784 parts, the acidity regulator is sodium citrate, and the Cardia Salt is potassium chloride, The minerals premixed powder includes calcium, phosphorus, iron, magnesium and zinc, 180.7~271.0 parts of calcium, phosphorus 93.34 based on its parts by weight ~140.0 parts, 4.952~7.429 parts of iron, 54.86~82.29 parts of magnesium, 2.899~4.349 parts of zinc.
A kind of preparation method of the full nutrient formulation powder of the hypotonic type of low fat, includes the following steps:
A) weigh: accurate weighing weight ratio be 40~55 parts of carbohydrate, 1~7 part of Medium chain fatty,
22~38 parts of high-quality protein, 1~5 part of L-Glutamine, 0~7 part of thickener, 0~10 part of sweetener, 0~3.5 part of edible essence, 0~2 part of emulsifier, 0~1.5 part of vitamin premixed powder, 0~2.5 part of left-handed meat Alkali, 1~1.5 part of acidity regulator, 0~1 part of Cardia Salt and 1.5~2.5 parts of minerals premixed powder;
B) it crushes: after the bigger crushing material of granularity and will be sieved;
C) it premixes: the fewer material of additive amount is premixed and is sieved with portion carbohydrate;
D) total mix: all materials are subjected to total mix and merge sieving;
E) it dispenses: the material after total mix is distributed into the product of 30~50g/ packet.
Preferably, by the bigger crushing material of granularity to 30~50 mesh in the step b).
Beneficial effects of the present invention: formula of the invention has the characteristics that low fat, high protein and Hi CHO, Middle fat is entirely Medium chain fatty, and gastrointestinal tolerant is good, has stronger specific aim, can be improved the tolerance of enteral nutrition preparation Property, while providing fully nutrient, patient is made to be not susceptible to diarrhea, improve the nutrition condition of patient, improves the life of patient Quality is very suitable for the patient of the poor easy generation diarrhea of gastrointestinal function or needs the crowd of low fat diet, such as inflammation Property bowel disease, after the Pancreatitis Patients just transition of oral diet, patients with heart failure, fasting initially using the patient of enteral nutrition, After cholecystitis, Patients with Cholelithiasis, cholecystectomy patient, obese people, intestinal surgery prepare patient and gastrointestinal procedures Patient etc. integrally reconstitutes, saves conveniently, can better meet actual clinical application.
Feature and advantage of the invention will be described in detail by embodiment combination attached drawing.
[Detailed description of the invention]
Fig. 1 is the nutritional ingredient figure of embodiment one;
[specific embodiment]
Embodiment one:
The maltodextrin that 53.49 part of accurate weighing weight ratio, 2 parts of medium chain triglyceride powder, 18 parts of lactalbumin Powder, 12 parts of soybean separation protein white powder, 5 parts of crystal diabetin, 3 parts of L-Glutamine, 0.22 part of guar gum, 0.18 part Xanthan gum, 0.2 part of vanilla, 0.2 part of milk powder essence, 0.5 part of soybean lecithin, 0.1 part powder flax Seed oil, 0.5 part of vitamin premixed powder, 2.1 parts of minerals premixed powder, 0.66 part of L-carnitine, 1.3 parts of lemon Sour sodium and 0.55 part of potassium chloride.The bigger crystal diabetin of granularity, potassium chloride, L-carnitine and sodium citrate are crushed It is sieved after to 40 mesh.By the fewer powder linseed oil of additive amount, vitamin premixed powder, guar gum and xanthan gum and portion Maltodextrin is divided to be premixed and be sieved.By the fewer soybean lecithin of additive amount, minerals premixed powder, vanilla, ox Milk powdered flavor and L-Glutamine are premixed and are sieved with part maltodextrin.Will premix sieving after two premixes, Precomminution material after pulverizing and sieving carries out total mix with surplus material and merges sieving.Material after total mix is distributed into the production of 40g/ packet Product.
Embodiment two:
The maltodextrin that 45 part of accurate weighing weight ratio, 2 parts of medium chain triglyceride powder, 16 parts of PURE WHEY, 10 parts of soybean separation protein white powder, 3 parts of crystal diabetin, 2 parts of L-Glutamine, 1 part of guar gum, 1 part of xanthan gum, 0.5 part of vanilla, 0.5 part of milk powder essence, 0.5 part of soybean lecithin, 0.5 part of powder linseed oil, 0.5 part Vitamin premixed powder, 1.8 parts of minerals premixed powder, 1 part of L-carnitine, 1.2 parts of sodium citrate and 0.3 part Potassium chloride.It is sieved after the bigger crystal diabetin of granularity, potassium chloride, L-carnitine and sodium citrate are crushed to 40 mesh. By the fewer powder linseed oil of additive amount, vitamin premixed powder, guar gum and xanthan gum and part maltodextrin into Row is premixed and is sieved.By the fewer soybean lecithin of additive amount, minerals premixed powder, vanilla, milk powder essence and L-Glutamine is premixed and is sieved with part maltodextrin.After two premixes after being sieved will be premixed, pulverized and sieved Precomminution material carries out total mix with surplus material and merges sieving.Material after total mix is distributed into the product of 40g/ packet.
Embodiment three:
The maltodextrin that 50 part of accurate weighing weight ratio, 4 parts of medium chain triglyceride powder, 20 parts of PURE WHEY, 14 parts of soybean separation protein white powder, 7 parts of crystal diabetin, 4 parts of L-Glutamine, 3 parts of guar gum, 2 parts of xanthan gum, 1 part of vanilla, 1.5 parts of milk powder essence, 1.5 parts of soybean lecithin, 1.5 parts of powder linseed oil, 1 part of dimension Raw element premixed powder, 2.3 parts of minerals premixed powder, 2 parts of L-carnitine, 1.4 parts of sodium citrate and 0.7 part of chlorine Change potassium.It is sieved after the bigger crystal diabetin of granularity, potassium chloride, L-carnitine and sodium citrate are crushed to 40 mesh.It will add The fewer powder linseed oil of dosage, vitamin premixed powder, guar gum and xanthan gum and part maltodextrin carry out pre- It mixes and is sieved.By the fewer soybean lecithin of additive amount, minerals premixed powder, vanilla, milk powder essence and L- paddy Glutamine is premixed and is sieved with part maltodextrin.By the pre- powder after premixing two premixes after being sieved, pulverizing and sieving Particle carries out total mix with surplus material and merges sieving.Material after total mix is distributed into the product of 40g/ packet.
Eating method: it is recommended that daily 6 packet, 1 is wrapped every time;
Reconstitute step:
1. 30mL or so warm water (50 DEG C) is added;2. pouring into the packet of this product 1 to stir evenly;3. warm water is reconstituted to 200mL i.e. It can.
The present invention is hypotonic formula, and osmotic pressure is lower than 300mmol/L H2O, it is not easy to cause abdominal distension, diarrhea and other intestines Road reaction, Intestinal Mucosal Injury in Patients Undergoing tolerance are more preferable.Forced for vitamins and minerals addition of the present invention, can take the photograph according to China's resident's nutrient Enter guidelines addition multivitamin and minerals, a variety of diseases caused by lacking because of vitamin and mineral can be prevented and treated.Powder The enteral nutrition preparation of dosage form is easy to save, and is easily adjusted the amount reconstituted and osmotic pressure, and using flexible is orally available.
The present invention is free of seitan, is low slag formula, can reduce the mechanical irritation to enteron aisle, reduces intestinal tympanites and diarrhea hair Raw rate, the patient during being extremely suitable for that alimentary tract rest, function of intestinal canal is needed to restore, such as gastrointestinal function chump, Yi Fasheng diarrhea Initially using enteral nutrition person, patients with inflammatory bowel disease, Pancreatitis Patients, just the transition of oral diet, heart failure are suffered from after person, fasting The patients such as after person, intestinal surgery preparation patient, gastrointestinal procedures.
Present protein source is lactalbumin and soybean protein these high-quality proteins, it is necessary to amino acid content is abundant, Amino acid pattern is easily absorbed and utilized close to human body, and it can be gastrointestinal tract mucosa that contained glutamine, which is conditionally essential amino acid, Nutrition is provided.
The adipose-derived present invention is medium chain triglyceride powder, complete hydrolysis can be fatty acid and sweet under pancreatic lipase effect Oil is rapidly absorbed, and is but not easy again three ester of synthetic glycerine after by small intestinal absorption, is suitble to the bad person of fat absorption, is easy to disappear Change, can be absorbed in the case where pancreatic lipase and bile salt shortage.
Above-described embodiment is the description of the invention, is not limitation of the invention, after any pair of simple transformation of the present invention Scheme all belong to the scope of protection of the present invention.

Claims (4)

1. a kind of full nutrient formulation powder of the hypotonic type of low fat, it is characterised in that: the carbon hydrate for being 40~55 parts including weight ratio Object, 1~7 part of Medium chain fatty, 22~38 parts of high-quality protein, 1~5 part of L-Glutamine, 0~7 part of thickener, 0~ 10 parts of sweetener, 0~3.5 part of edible essence, 0~2 part of emulsifier, 0~1.5 part of vitamin premixed powder, 0~ 2.5 parts of L-carnitine, 1~1.5 part of acidity regulator, 0~1 part of Cardia Salt and 1.5~2.5 parts of minerals premix Close powder.
2. a kind of full nutrient formulation powder of the hypotonic type of low fat as described in claim 1, it is characterised in that: the carbohydrate is Maltodextrin, the Medium chain fatty are the mixture of one or both of medium chain triglyceride powder and powder linseed oil, institute The mixture that high-quality protein is one or both of PURE WHEY and soybean separation protein white powder is stated, the thickener is Guar The mixture of one or both of bean gum and xanthan gum, the sweetener are crystal diabetin, and the edible essence is that vanilla is fragrant The mixture of essence and one or both of milk powder essence, the emulsifier are soybean lecithin, the vitamin premixing Powder includes vitamin A, vitamin D, vitamin E, vitamin B1, niacin, pantothenic acid, vitamin B6, vitamin C, taurine, dimension life Plain B2, folic acid and vitamin B12, 1120~1680 parts of vitamin A, vitamin D 2.640~3.960 based on its parts by weight Part, 20580~30870 parts of vitamin E, vitamin B12816~4224 parts, 27616~41424 parts of niacin, pantothenic acid 7824~ 11736 parts, vitamin B62624~3936 parts, 300000~450000 parts of vitamin C, taurine 201600~302400 Part, vitamin B22432~3648 parts, 349.4~524.2 parts of folic acid, vitamin B125.856~8.784 parts, the acidity tune Section agent is sodium citrate, and the Cardia Salt is potassium chloride, and the minerals premixed powder includes calcium, phosphorus, iron, magnesium and zinc, by it 180.7~271.0 parts of parts by weight meter calcium, 93.34~140.0 parts of phosphorus, 4.952~7.429 parts of iron, magnesium 54.86~82.29 Part, 2.899~4.349 parts of zinc.
3. a kind of preparation method of the full nutrient formulation powder of the hypotonic type of low fat, it is characterised in that include the following steps:
A) weigh: accurate weighing weight ratio is 40~55 parts of carbohydrate, 1~7 part of Medium chain fatty, 22~38 parts High-quality protein, 1~5 part of L-Glutamine, 0~7 part of thickener, 0~10 part of sweetener, 0~3.5 part of edible perfume (or spice) Essence, 0~2 part of emulsifier, 0~1.5 part of vitamin premixed powder, 0~2.5 part of L-carnitine, 1~1.5 part of acidity Regulator, 0~1 part of Cardia Salt and 1.5~2.5 parts of minerals premixed powder;
B) it crushes: after the bigger crushing material of granularity and will be sieved;
C) it premixes: the fewer material of additive amount is premixed and is sieved with portion carbohydrate;
D) total mix: all materials are subjected to total mix and merge sieving;
E) it dispenses: the material after total mix is distributed into the product of 30~50g/ packet.
4. a kind of full nutrient formulation powder of the hypotonic type of low fat as claimed in claim 3 and preparation method thereof, it is characterised in that: described By the bigger crushing material of granularity to 30~50 mesh in step b).
CN201910671973.0A 2019-07-24 2019-07-24 A kind of full nutrient formulation powder of the hypotonic type of low fat and preparation method thereof Pending CN110463988A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112890179A (en) * 2021-03-01 2021-06-04 成都尚医信息科技有限公司 Semi-solidified nutrient for solving enteral nutrition intolerance and preparation method thereof

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CA2944529A1 (en) * 2014-08-07 2016-02-11 Mingfu Lu Complete nutritional powder and preparation method thereof
CN106616998A (en) * 2016-12-30 2017-05-10 北京康比特体育科技股份有限公司 Nutrition meal replacement composition and application thereof
CN107252109A (en) * 2017-07-10 2017-10-17 北京素维生物科技有限公司 Function nutrition hardening agent composition and preparation method thereof
CN107307390A (en) * 2017-07-10 2017-11-03 北京素维生物科技有限公司 Function nutrition hardening agent composition and preparation method
CN107343657A (en) * 2017-06-05 2017-11-14 深圳市捷利康生物科技有限公司 High fat diet formula powder
CN108968046A (en) * 2018-07-25 2018-12-11 哈尔滨拜仑斯特临床营养有限公司 A kind of special medicine purposes full nutrition formula food and preparation method thereof

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CA2944529A1 (en) * 2014-08-07 2016-02-11 Mingfu Lu Complete nutritional powder and preparation method thereof
CN105054025A (en) * 2015-08-09 2015-11-18 青岛大学附属医院 Low-fat low-osmosis low-residue type enteral nutritional powder for patients with inflammatory bowel diseases
CN106616998A (en) * 2016-12-30 2017-05-10 北京康比特体育科技股份有限公司 Nutrition meal replacement composition and application thereof
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112890179A (en) * 2021-03-01 2021-06-04 成都尚医信息科技有限公司 Semi-solidified nutrient for solving enteral nutrition intolerance and preparation method thereof

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Application publication date: 20191119