CN110448805A - A kind of catagmatic magnet therapy bandage of additional steady magnetic field - Google Patents
A kind of catagmatic magnet therapy bandage of additional steady magnetic field Download PDFInfo
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- CN110448805A CN110448805A CN201910765335.5A CN201910765335A CN110448805A CN 110448805 A CN110448805 A CN 110448805A CN 201910765335 A CN201910765335 A CN 201910765335A CN 110448805 A CN110448805 A CN 110448805A
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- 238000002653 magnetic therapy Methods 0.000 title claims abstract description 28
- 230000035876 healing Effects 0.000 claims abstract description 20
- 210000000988 bone and bone Anatomy 0.000 claims description 38
- 241000700159 Rattus Species 0.000 claims description 28
- 210000000689 upper leg Anatomy 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 18
- 210000004417 patella Anatomy 0.000 claims description 14
- 206010002091 Anaesthesia Diseases 0.000 claims description 7
- 230000037005 anaesthesia Effects 0.000 claims description 7
- 230000001054 cortical effect Effects 0.000 claims description 7
- 238000003780 insertion Methods 0.000 claims description 7
- 230000037431 insertion Effects 0.000 claims description 7
- 239000007928 intraperitoneal injection Substances 0.000 claims description 7
- 230000003447 ipsilateral effect Effects 0.000 claims description 7
- 239000010410 layer Substances 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 210000003314 quadriceps muscle Anatomy 0.000 claims description 7
- 239000000243 solution Substances 0.000 claims description 7
- 206010052428 Wound Diseases 0.000 claims description 6
- 208000027418 Wounds and injury Diseases 0.000 claims description 6
- 239000006249 magnetic particle Substances 0.000 claims description 5
- 238000012795 verification Methods 0.000 claims description 5
- 239000002344 surface layer Substances 0.000 claims description 3
- 230000029663 wound healing Effects 0.000 claims description 3
- 238000002513 implantation Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 208000010392 Bone Fractures Diseases 0.000 abstract description 53
- 206010017076 Fracture Diseases 0.000 abstract description 48
- 230000000694 effects Effects 0.000 abstract description 8
- 230000001737 promoting effect Effects 0.000 abstract description 4
- 238000002474 experimental method Methods 0.000 abstract description 3
- 238000009940 knitting Methods 0.000 abstract description 3
- 208000008924 Femoral Fractures Diseases 0.000 description 5
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 description 4
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 description 4
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 230000005672 electromagnetic field Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 208000020084 Bone disease Diseases 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 206010006956 Calcium deficiency Diseases 0.000 description 1
- 102000003712 Complement factor B Human genes 0.000 description 1
- 108090000056 Complement factor B Proteins 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 208000015813 Familial avascular necrosis of femoral head Diseases 0.000 description 1
- 208000005214 Poroma Diseases 0.000 description 1
- 102000009618 Transforming Growth Factors Human genes 0.000 description 1
- 108010009583 Transforming Growth Factors Proteins 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 208000037873 arthrodesis Diseases 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 210000004271 bone marrow stromal cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000008358 core component Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 201000001013 eccrine acrospiroma Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000003716 mesoderm Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000004072 osteoblast differentiation Effects 0.000 description 1
- 230000002188 osteogenic effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000009256 replacement therapy Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/06—Magnetotherapy using magnetic fields produced by permanent magnets
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Magnetic Treatment Devices (AREA)
Abstract
The present invention relates to a kind of additional catagmatic magnet therapy bandages of steady magnetic field, are made of medical bandage and magnet, and in the side of medical bandage, there is a magnet in longitudinal direction every 2-8cm, and bandage length can be adjusted according to different fracture sites.The present invention has intuitively reacted the effect that magnetic field promotes union, the especially magnet therapy bandage of higher magnetic field intensity and has more preferably promoted knitting effect faster for fracturing to have, and is that application of the magnet therapy bandage in bone fracture is clinical provides fact basis.The present invention establishes SD rat fracture model, has intuitively reacted the science and reliability of data.Reaction condition is controllable in the present invention, and experimental method is simple, strong operability, has absolutely proved magnetic therapy in the application prospect in promoting bone fracture healing field.
Description
Technical field
The present invention relates to the magnet therapy bandage that a kind of additional steady magnetic field promotes union, specific verification method is to establish greatly
After mouse Femoral Fracture Model, additional steady magnetic field paster method is carried out to it and carries out therapeutic intervention, the results showed that, additional steady magnetic field
The healing of fracture is promoted, so having invented the practical magnet therapy bandage.The invention belongs to field of medical biology.
Background technique
The intensity of steady magnetic field (SMF also cries magnetostatic field, stationary magnetic field etc.) does not change over time, most common in life
Steady magnetic field is the magnet of household, the core component of the magnetic resonance imager (MRI) in hospital and faint but be widely present
Earth's magnetic field is all the different steady magnetic field of intensity.The magnetic field strength that people touch is from the 0.05mT in earth's magnetic field to close to MRI's
10T etc..
Scientists have carried out the much research about magnetic field in terms of bone disease, it was demonstrated that magnetic field can promote osteopathy health
Multiple biological effect.1970s have scholar be put forward for the first time using electromagnetic field (electromagnetic field,
EMF) treat nonunion, later, electromagnetic field be suggested again can be used for congenital bone defect, arthrodesis fail, bone it is bad
Extremely (such as aseptic necrosis of head of femur), bone collection and the postoperative treatment of spinal vertebral Bony union, we guess steady magnetic field
There is same effect, moreover, for many years, magnetic field in treatment bone nonunion and promotes the bones such as knitting as a kind of physical replacement therapy
Section field, which has obtained extensive research, has shown that it in terms of promoting union, shortening healing time, improve
There is good curative effect.But it is up to the present still not clear with the specific mechanism of the above-mentioned disease of magnetic field treatment, many researchs confirm magnetic
Field stimulation can promote the proliferation of mesenchymal stem cell, and cause the secretion of bone relevant growth factors, and certain growth factors
It is directed differentiation to inducing bone mesenchymal stem cell (bone arrow mesenchymal stem cells, BMSCs)
The effect of bone.And have document report, fibroblast growth factor 2 (fibroblast growth factor-2, FGF-2)
Reach promotion bone with inhibition transforming growth factor B (trans ng growth factor-B, TF-B) signal path is passed through
Effect of the bone marrow-drived mesenchymal stem to osteoblast differentiation, for this reason, it is contemplated that electromagnetic stimulation can increase pipe marrow mesenchyma
The expression of stem cell FGF-2 or FGHR2=RNA, and will expose after the Bone Marrow Mesenchymal Stem Cells Transplantation after magnetic enters in vivo, it can be with
Promote the healing of fracture.Thus, it devises this experiment and has invented magnet therapy bandage, mainly studied in terms of external two in vivo steady
Contacting between state magnetic field and skeletonization is preferably applied for clinic for magnetic field and provides theoretical foundation.
Maximum a part belongs to self-control one kind in existing " magnetic therapy ", is mainly mentioned using various types of permanent magnets
Various diseases are treated for the static magnetic field of " continuous openness ".For example, magnetic bed mattress, embedded magnet type pillow, Magnetotherapeutic insole, magnetic
Property harness, magnetic bracelet etc., these magnetic therapy products can be used for the different parts of body, and magnetic field strength range is tens to arrive
Several hundred Gausses, the penetration that these magnetic fields rely primarily on magnetic field influence vital tissues or organ.
Currently, the physical therapy principle of steady magnetic field still lacks enough theory supports, do not received by mainstream health care, this
It is to go analysis factor relevant to magnetic field due to lacking the method for scientific system.Although can not temporarily be solved there are also many problems,
But the present invention has studied influence of the steady magnetic field to union, and devises reasonable promoting bone fracture healing bandage.
Summary of the invention
In view of the deficiencies of the prior art, it is an object of that present invention to provide the magnetic that a kind of additional steady magnetic field promotes union
Treat bandage.
The object of the invention is realized by following proposal: a kind of additional steady magnetic field promotes the magnet therapy bandage of union,
It is characterized in that: being made of medical bandage and magnet, in the side of medical bandage, there is a magnet in longitudinal direction every 2-8cm, and bandage is long
It is short to be adjusted according to different fracture sites.
The magnet is embedded magnetic sheet type, and position is fixed inside bandage and is implanted into suitable magnetic sheet, radius 1.0cm, thickness
Less than 5mm, intensity 0.2-0.4T, it is mainly used for lesser slight of specific position, fracture wound shorter away from skin surface distance
Fracture.
The magnet is the particles filled type of magnetic, strong magnetic particle is filled inside bandage, intensity 0.4-0.8T is mainly used for
Fixation is covered in fracture surface after the wound healing of surface layer, is suitable for biggish apart from the farther away fracture of body surface and fracture wound
Position.
Embedded magnetic sheet type bandage verification method is as follows:
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, and the modeling method rolled over using closed femur takes right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, and it is recessed to expose femoral intercondylar, from stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris, then takes out, inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful, then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture；One week
Embedded magnetic sheet type bandage is wound in fracture appearance afterwards, 1 X-ray observation fracture is clapped towards fracture, normal feeding in the pole N every 2 weeks
Healing.
The particles filled type bandage verification method of magnetic is as follows:
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, and the modeling method rolled over using closed femur takes right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, and it is recessed to expose femoral intercondylar, from stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris, then takes out, inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful.Then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture；One week
The particles filled type bandage of magnetic is wound in fracture appearance afterwards, the pole N is towards fracture, and normal to feed, 1 X-ray of bat observes bone every 2 weeks
Roll over healing.
Influence of the steady magnetic field that the present invention arrives according to the observation to speed of fracture union, finds the steady magnetic field of certain field strength
It can promote union process.This method is controlled by intervene to the additional steady magnetic field paster method of rat fracture model progress
It treats, then with apparently analyzing and statistical analysis is drawn a conclusion the potential value for proving the invention in terms of medical treatment & health.
The present invention is using Rat Femoral Fracture as model.Control group is normally raised, and experimental group is normally raised additional steady after a week
The raising of state magnetic field, i.e. bondage magnet therapy bandage, the pole N is to fracture face, and surface magnetic strength is respectively 0.2T, 0.4T, and other conditions are identical, X
Light characterization result contrasting data each other.It can promote union for magnetic therapy and rationally application provides fact basis, and design
The magnet therapy bandage of union is gone out to effectively promote.
The present invention has the advantages that
(1) present invention has intuitively reacted the effect that magnetic field promotes union, the especially magnet therapy bandage pair of higher magnetic field intensity
There is more preferable rush knitting effect faster in fracture, provide fact basis for application of the magnet therapy bandage in bone fracture clinic.
(2) present invention establishes SD rat fracture model, has intuitively reacted the science and reliability of data.
(3) reaction condition is controllable in the present invention, and experimental method is simple, strong operability, has absolutely proved that magnetic therapy is promoting bone
Roll over the application prospect of healing art.
Detailed description of the invention
Attached drawing 1 is embedded magnetic sheet type bandage design schematic diagram；
Attached drawing 2 is the particles filled type bandage design schematic diagram of magnetic；
Attached drawing 3 is the healing state figure of 1 Rat Femoral Fracture of embodiment；
Attached drawing 4 is the healing state figure of 2 Rat Femoral Fracture of embodiment；
Attached drawing 5 is the healing state figure of 3 Rat Femoral Fracture of embodiment.
Specific embodiment
Below by way of specific embodiment, the technical scheme of the present invention will be further described.Embodiment below is to this
The further explanation of invention, and do not limit the scope of the invention.
Embodiment 1
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, the modeling method rolled over using closed femur.Take right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, it is recessed to expose femoral intercondylar.From stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris.It then takes out, it is inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful.Then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture.Normally
Feeding does not use magnet therapy bandage from beginning to end, claps 1 X-ray every 2 weeks and observes bone fracture healing, as a control group.
Control group does not use magnet therapy bandage.Attached drawing 3 is this group of healing state phenogram, wherein after model is established in figure a expression
Fracture situation at one week schemes b to be spaced the union figure clapped when third week.It can be seen that after two weeks, fracture has significantly
Healing, but former gap of fracturing is still more apparent.
Embodiment 2
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, the modeling method rolled over using closed femur.Take right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, it is recessed to expose femoral intercondylar.From stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris.It then takes out, it is inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful.Then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture.One week
Embedded magnetic sheet type bandage is wound in fracture appearance afterwards, and the pole N is towards fracture.1 X-ray observation fracture is clapped in normal feeding every 2 weeks
Healing.
Using embedded magnetic sheet type magnet therapy bandage group shown in FIG. 1, it is made of medical bandage and magnet, the one of medical bandage
Side is arranged in two rows, and there is a magnet in longitudinal direction every 2-8cm, and the magnet is embedded magnetic sheet type, and position is fixed inside bandage
It is implanted into the magnetic sheet of radius 1.0cm, thickness no more than 5mm and intensity 0.2-0.4T, for, fracture wound shorter away from skin surface distance
The lesser slight fracture of mouth.
As shown in Fig. 4, figure a indicate establish model it is latter week when fracture situation, scheme b to be clapped X-ray picture after three weeks,
Fracture has apparent healing, and has several spur to grow, and caused by possible calcium deficiency either osteogenic growth is too fast, but it is former to fracture
Gap, which obviously has, largely heals.
Embodiment 3
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, the modeling method rolled over using closed femur.Take right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, it is recessed to expose femoral intercondylar.From stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris.It then takes out, it is inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful.Then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture.One week
The particles filled type bandage of magnetic is wound in fracture appearance afterwards, the pole N is towards fracture.Normal feeding claps 1 X-ray every 2 weeks and observes bone
Roll over healing.
It is in two one group using the strong magnetic particle bandage group of filled-type as shown in Figure 2, the arrangement of two rows, every group of two intergranulars
Spacing be 2-8cm, the magnet be the strong magnetic particle of filled-type, inside bandage fill intensity be 0.4-0.8T strong magnetic
Grain is covered in fracture table for fixation after the larger and surface layer wound healing apart from the farther away fracture of body surface and fracture wound
Face.
As shown in Fig. 5, fracture situation when figure a indicates to establish model latter week, figure b is X-ray after three weeks.It can be seen that making
With the rat of the particles filled type bandage of magnetic, fracture has apparent healing, and poroma is obvious, and fracture heals substantially.More obvious after
It is better than without using magnet therapy bandage group and embedded magnetic sheet type magnet therapy bandage group.
Claims (5)
1. a kind of additional steady magnetic field promotes the magnet therapy bandage of union, using medical bandage as substrate, it is characterised in that: by curing
It is formed with bandage and magnet, in the side of medical bandage, there is a magnet in longitudinal direction every 2-8cm, and bandage length is according to different bones
Folding part position is adjusted.
2. additional steady magnetic field promotes the magnet therapy bandage of union according to claim 1, it is characterised in that: the magnet
To embed magnetic sheet type, position implantation radius 1.0cm, magnetic of the thickness no more than 5mm and intensity 0.2-0.4T are fixed inside bandage
Piece, for, fracture wound lesser slight fracture shorter away from skin surface distance.
3. additional steady magnetic field promotes the magnet therapy bandage of union according to claim 1, it is characterised in that: the magnet
For the strong magnetic particle of filled-type, the strong magnetic particle that intensity is 0.4-0.8T is filled inside bandage, for apart from the farther away bone of body surface
Folding and fracture after wound is larger and surface layer wound healing fixation be covered in fracture surface.
4. a kind of additional steady magnetic field according to claim 1 or claim 2 promotes the magnet therapy bandage verification method of union, special
Sign is that steps are as follows:
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, and the modeling method rolled over using closed femur takes right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, and it is recessed to expose femoral intercondylar, from stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris, then takes out, inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful, then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture；One week
Embedded magnetic sheet type bandage is wound in fracture appearance afterwards, 1 X-ray observation fracture is clapped towards fracture, normal feeding in the pole N every 2 weeks
Healing.
5. according to claim 1 or the magnet therapy bandage verification method of the 3 additional steady magnetic fields promotion unions, feature exist
In steps are as follows:
Female sd inbred rats three similar in of the same age and weight are chosen, with 10% chloraldurate solution according to 0.3mL/100g to rat
Intraperitoneal injection of anesthesia is carried out respectively, and the modeling method rolled over using closed femur takes right lower extremity kneecap inner incision longitudinal incision
About 1.0cm, quadriceps muscle of thigh key longitudinal incision part, kneecap is led and causes its dislocation outward, and it is recessed to expose femoral intercondylar, from stock
The intercondylar recess of bone is inserted into sterile No. 20 syringe needle and is inserted to femoral intertrochanteric expansion marrow along femoral bone cavitas medullaris, then takes out, inverse
To femoral intertrochanteric, the distal end of Kirschner wire is embedded under femoral intercondylar cortical bone row insertion Kirschner wire diameter, and layer-by-layer suture operation is cut
Mouthful.Then rat to be lain on the back, Ipsilateral femur outreach inward turning position is fixed on fracture apparatus, big midleg is then gently pressed with osteotome,
Assistant lifts counterweight to highly about 50cm, osteotome is hit by freely falling body, so that the middle section for hitting femur causes to fracture；One week
The particles filled type bandage of magnetic is wound in fracture appearance afterwards, the pole N is towards fracture, and normal to feed, 1 X-ray of bat observes bone every 2 weeks
Roll over healing.
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| CN201910765335.5A CN110448805A (en) | 2019-08-19 | 2019-08-19 | A kind of catagmatic magnet therapy bandage of additional steady magnetic field |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1093293A (en) * | 1994-02-04 | 1994-10-12 | 朱奋芝 | Magnetic therapeutic apparatus for treating fracture |
| CN106725971A (en) * | 2017-01-05 | 2017-05-31 | 中国人民解放军总医院 | One kind experiment fracture modeling pincers and its application method |
| CN108742923A (en) * | 2018-03-23 | 2018-11-06 | 云南省第人民医院 | A kind of construction method of osteoporotic fracture disease animal model and application |
-
2019
- 2019-08-19 CN CN201910765335.5A patent/CN110448805A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1093293A (en) * | 1994-02-04 | 1994-10-12 | 朱奋芝 | Magnetic therapeutic apparatus for treating fracture |
| CN106725971A (en) * | 2017-01-05 | 2017-05-31 | 中国人民解放军总医院 | One kind experiment fracture modeling pincers and its application method |
| CN108742923A (en) * | 2018-03-23 | 2018-11-06 | 云南省第人民医院 | A kind of construction method of osteoporotic fracture disease animal model and application |
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