CN110420150A - A kind of anti-aging skin care product composition containing Moringa seed extract - Google Patents

A kind of anti-aging skin care product composition containing Moringa seed extract Download PDF

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Publication number
CN110420150A
CN110420150A CN201910871506.2A CN201910871506A CN110420150A CN 110420150 A CN110420150 A CN 110420150A CN 201910871506 A CN201910871506 A CN 201910871506A CN 110420150 A CN110420150 A CN 110420150A
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extract
oil
care product
skin
skin care
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江艳
袁立新
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Shenzhen Yueqing Health Technology Co Ltd
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Shenzhen Yueqing Health Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Gerontology & Geriatric Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of anti-aging skin care product composition containing Moringa seed extract.By weight percentage, the raw material components which includes: emollient 7-20%;Moisturizer 5.05-10.5%;Emulsifier 1.0-3.0%;Plant extracts 0.5-1.0%;Plants essential oil compound 0.5-5%;Other skin conditioning agents 1.31-4.15%;Antioxidant 0.2-0.5%;Preservative 0.2-0.5%;Surplus is aqueous solvent.The anti-aging skin care product composition that the present invention contains Moringa seed extract can supplement skin moisture and nutrient, and moisturizing keeps skin soft and smooth, fine and smooth glossy.After clean skin, appropriate this product is taken to be applied to the bodies skin such as neck, back, abdomen and four limbs, professional gimmick is cooperated to carry out massage operation, can get persistently effective senile-resistant efficacy.

Description

A kind of anti-aging skin care product composition containing Moringa seed extract
Technical field
The present invention relates to a kind of ageing-resistant skin care compositions, belong to daily skin-protection product technical field, more particularly to one Anti-aging skin care product composition of the kind containing Moringa seed extract.
Background technique
Moringa seeds originate from India, are India most ancient medicinal, food plants.Using existing in Ayurvedic medicine More than 4000 years history, referred to as " tree of mystery " have very high health and medical value.
Studies have shown that Moringa tree is proved to be worth containing abundant nutrition, its health-care effect also thus become healthy food The new lover of product circle.Everybody, which may not believe, also contains Moringa seed extract inside cosmetics.
Since the ability of moringa seeds water conservation is very serious, cause enables it to grow in the adverse circumstances of limit arid area, because Contain the active constituent that can catch moisture for it.Therefore, moringa seeds are widely used in make-up and beauty industry.
In cosmetic industry, Moringa seed extract has many skin-care effects, but how by the shield of the Moringa seed extract Skin efficacy exertion is to greatly;And other skin care ingredients is cooperated to reach synergistic function, it is that the field technical staff is badly in need of The technical problem of solution.
Summary of the invention
The object of the present invention is to provide a kind of anti-aging skin care product composition containing Moringa seed extract, can quickly mend Skin moisture and nutrient are filled, moisturizing keeps skin soft and smooth, fine and smooth glossy.
The object of the invention to solve the technical problems adopts the following technical solutions to realize.It proposes according to the present invention A kind of anti-aging skin care product composition containing Moringa seed extract, by weight percentage, include following raw material components:
Emollient 7-20%;
Moisturizer 5.05-10.5%;
Emulsifier 1.0-3.0%;
Plant extracts 0.5-1.0%;
Plants essential oil compound 0.5-5%;
Other skin conditioning agents 1.31-4.15%;
Antioxidant 0.2-0.5%;
Preservative 0.2-0.5%;
Surplus is aqueous solvent.
Furthermore, in the anti-aging skin care product composition containing Moringa seed extract, the emollient is selected from Ring five dimethyl silicone polymer, one kind of saualane or its mixing;The emulsifier is selected from PEG-10 Polydimethylsiloxane.
Furthermore, in the anti-aging skin care product composition containing Moringa seed extract, the plant extracts It selects:
German chamomile flower extract;Gotu Kola P.E;Licorice root extract;Tea extract;Polygonum cuspidate root extract;Rosemary Leaf extract;Seven kinds of radix scutellariae root extract are the mixture of 1:1:1:1:1:1:1 according to mass ratio.
Furthermore, in the anti-aging skin care product composition containing Moringa seed extract, the moisturizer is selected from One of 1,3- propylene glycol, Sodium Hyaluronate or its mixing;
The antioxidant is selected from one of tocopherol acetate, vitamin C, vitamin E or its mixing;
The preservative is selected from one of Phenoxyethanol, hexylene glycol, Chlorphenesin or its mixing.
Furthermore, in the anti-aging skin care product composition containing Moringa seed extract, the plants essential oil is multiple Object is closed to be selected from:
5 kinds of seed oil of Moringa oleigera, patchouli oil, cinnamon oil, Java Cananga Oil, rose oil components are 1:1:1:1:1 according to mass ratio Mixture.
Furthermore, in the anti-aging skin care product composition containing Moringa seed extract, other described skin tune Managing agent includes Wild soybean oil 0.01-0.3%;Dipotassium glycyrrhizinate 0.05-0.3%;Polyglutamic acid sodium 0.05-0.3%;Sodium citrate 0.2-0.5%;Cornstarch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl methyl cellulose and CT77492 mixture 0.1- 0.5%.
The above-mentioned anti-aging skin care product composition containing Moringa seed extract is by weight percentage by following raw material Group is grouped as:
Ring five dimethyl silicone polymer 5-15%, 1,3- propylene glycol 5-10%, PEG-10 Polydimethylsiloxane -3%, angle Shark alkane 2-5%, Wild soybean oil 1-3%, plant extracts (are extracted comprising german chamomile flower extract, Gotu Kola P.E, licorice Object, tea extract, polygonum cuspidate root extract, rosemary leaf extract, radix scutellariae root extract) 0.5-1.0%, Sodium Hyaluronate 0.05-0.5%, dipotassium glycyrrhizinate 0.05-0.3%, polyglutamic acid sodium 0.05-0.3%, sodium citrate 0.2-0.5%, tocopherol Acetic acid esters 0.2-0.5%, seed oil of Moringa oleigera 0.1-1.0%, patchouli oil 0.1-1.0%, cinnamon oil 0.1-1.0%, Yilan caul-fat 0.1-1.0%, rose oil 0.1-1.0%, skin conditioning agent (include cornstarch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl Ylmethyl cellulose, CT77492) 0.1-0.5%, preservative (include hexylene glycol, Phenoxyethanol, Chlorphenesin) 0.2-0.5%, Surplus is water.
Furthermore, the preparation method of the above-mentioned anti-aging skin care product composition containing Moringa seed extract, be by with Lower processing step is made:
1) it adds water in water phase pot, opens stirring (50 revs/min), sequentially add 1,3-PD, Sodium Hyaluronate, gather Sodium glutamate, dipotassium glycyrrhizinate, sodium citrate are heated to 60 DEG C, dissolve fully transparent;
2) by ring five dimethyl silicone polymer, PEG-10 Polydimethylsiloxane, saualane, Wild soybean oil, tocopherol second Acid esters, seed oil of Moringa oleigera, patchouli oil, cinnamon oil, Yilan caul-fat, rose oil sequentially add in emulsion pot, open stirring;
3) it vacuumizes, slowly sucks water phase material, open homogeneous (2000 revs/min), homogeneous 15 minutes, start to drop Temperature;
4) plant extracts (german chamomile flower extract, Gotu Kola P.E, licorice root extract, tea extract, tiger is added Cane root extract, rosemary leaf extract, radix scutellariae root extract) and skin conditioning agent (cornstarch, microcrystalline cellulose, sucrose, Lactose, hydroxypropyl methyl cellulose, CI 77492), homogeneous 8 minutes;
5) it when being down to 40 DEG C, is added preservative (hexylene glycol, Phenoxyethanol, Chlorphenesin), 30 points of stirring (60 revs/min) Clock, discharging.
By above-mentioned technical proposal, the invention has the advantages that and advantageous effects:
1) present invention has softening epidermal cell, makes smooth skin, soft and moist, skin nutrition, supplement human amino acid, dispels Melanin inhibits tyrosinase to generate.Have a sterilization simultaneously, cleaning skin effect, can anti-acne, nti-freckle, it is dark yellow to improve skin, grows Profit, moisturizing, weight reducing and other effects can be widely used for cream, lotion, facial mask, hair-washing hair-care, eye.
2) present invention plays excellent senile-resistant efficacy;It can also be used in fluid purification, extract the top grades such as manufacture water conservation, sun-proof The active material etc. of cosmetics;When as unloading cosmetics, plant active peptides and polyphenoils can be discharged, it is mild to purify in skin Harmful absurd creature.
3) present invention has dual senile-resistant efficacy, has good market prospects and enough attractions.
Specific embodiment
The invention discloses a kind of anti-aging skin care product composition containing Moringa seed extract.By weight percentage, The raw material components that the anti-apolexis composition includes: emollient 7-20%;Moisturizer 5.05-10.5%;Emulsifier 1.0-3.0%; Plant extracts 0.5-1.0%;Plants essential oil compound 0.5-5%;Other skin conditioning agents 1.31-4.15%;Antioxidant 0.2-0.5%;Preservative 0.2-0.5%;Surplus is aqueous solvent.
The anti-aging skin care product composition that the present invention contains Moringa seed extract can supplement skin moisture and nutrient, moisten Skin keeps skin soft and smooth, fine and smooth glossy.After clean skin, appropriate this product is taken to be applied to the bodies such as neck, back, abdomen and four limbs Skin cooperates professional gimmick to carry out massage operation, can get persistently effective senile-resistant efficacy.
Raw material sources and effect of the invention are described below:
Material component of the invention is commercial product.
Skin conditioning agent of the invention selects seven kinds of active ingredients of plants compounds below, has multiple efficacies, such as exempts from Epidemic disease adjusting, anti-inflammatory and antioxidation.
For the seven kinds of active ingredients of plants compounds especially chosen, inhibits ten several inflammatory factors comprehensively, quickly prevent Caused scytitis due to various reasons inhibits the pernicious chain physiological reaction in inflammation each stage, there is class effects of antibiotics And it is safe without side-effects, while also have it is anti-oxidant, releive and the cooperative effect of moisturizing, particularly with allergic skin and baby's skin Skin nursing has obvious clinical effectiveness.
German chamomile 1. (CHAMOMILLA RECUTITA) flower extract:
That is chamomile, containing volatile oil, flavone compound, amino acid, chlorogenic acid and microelement etc..It is mentioned based on chrysanthemum It takes object that there are the bioactivity such as antibacterial, anti-oxidant, anti-inflammatory, antiallergic of releiving, is widely used in cosmetics, can play and prevent Quick, moisturizing, prevention and treatment acne and anti-aging and other effects.
Centella 2. (CENTELLA ASIATICA) extract:
Gotu Kola P.E can make skin limber up with compact epidermis and corium coupling part, and help promotes skin corium Middle collagen is formed, and has the effect for enabling skin compact.Functionally, it can promote blood circulation;Improve acne skin;It prevents Pigementation;The collagen of skin is promoted to generate, improve skin elasticity, delaying skin aging;After solarization after ultraviolet light irradiation Reparation has all been proved remarkable result.
Centella main component asiaticosid has facilitation to fibroblasts from hypertrophic scars vigor, so there is the work for scar of dispelling With, it is fine with phospholipid material polymerization effect, there is obvious effect to whelk is eliminated, there is inhibition to make heteroside aldehydic acid enzyme With, in addition have antibiotic property, play the role of inhibiting body odor very well;Have good facilitation to the growth of hair, this with it Promote cell viability related, can be used as product for improving hair-growing.
Radix Glycyrrhizae 3. (GLYCYRRHIZA URALENSIS) root extract:
Proliferation function of the licorice root extract to myocyte, the facilitation to vascular endothelial cell proliferation, to collagen egg The promotion that white -4 type generates, to the studies have shown thats licorice root extracts such as the NO inhibition generated improve skin in terms of There is facilitation, can be used for anti-ageing cosmetics;Licorice root extract has inhibition melanin, the effect of skin whitening simultaneously;It is right Some bacteriums significantly inhibit, and can be used as anti-inflammatory agent.
Tea 4. (CAMELLIA SINENSIS) leaf extract:
The extract of tealeaves is that tea polyphenols also known as tea tannin, tea rub matter, be it is a kind of be present in tealeaves mostly through base phenol Compound.Its main component is catechin (flavanol compound), two class of flavones and flavones, anthocyanidin and leucoanthocyanidin class and phenolic acid and contracting Four class such as phenolic acid class is the complex of more than 30 kinds of phenolic substancess composition.Pure natural extraction product has bodybuilding skin, delays The functions such as skin aging can remove intracorporal various free radicals, reach oxidation resistant effect, and wherein tea polyphenols have convergence Property, protein precipitation can be made to be denaturalized, therefore there is stronger antibacterial action.
Polygonum cuspidate 5. (POLYGONUM CUSPIDATUM) root extract:
There is good inhibiting effect to the activity of B-16 melanocyte, in addition, have facilitation to macrophage activity, Melanin content is reduced by the two aspects, can be used for whitening class cosmetics;There is inhibiting effect to elastoser, in conjunction with Inoxidizability is suitable for crease-resistant skin-active class skin care item.
Rosemary 6. (ROSMARINUS OFFICINALIS) leaf extract:
Rosemary Oil fragrance is pure and fresh, has sterilization, desinsection, anti-inflammatory isoreactivity, has very to red spider, mosquito and its worm's ovum Strong lethality, can be used for culicifuge and preparing essence.Rosemary leaf extract has fabulous antioxygenic property, a series of Cell culture test in, display the proliferation function to fiber sprout cell etc., the inhibition to elastoser, Collagenase and Antioxidant etc. illustrates that rosemary leaf extract has skin-active Antiageing effect;Also there is certain anti-inflammatory and convergent effect simultaneously.
Radix scutellariae 7. (SCUTELLARIA BAICALENSIS) root extract:
It can inhibit elastoser, interference secretion can eliminate free radical, to increase skin metabolism, increase skin Skin elasticity and wrinkle resistance, can be with anti-aging;Promote brain amide, and improving sebum keeps skin soft and moist;It can inhibit dermatitis, enhancing skin Resistance, have anti-inflammatory;The histamine that release can be neutralized, has the ability for preventing skin allergy.
2, the action principle and effect of plants essential oil compound are described as follows:
1. Moringa (MORINGA OLEIFERA) seed is oily: softening epidermal cell makes that skin is smooth, soft and moist, skin nutrition, benefit Fill human amino acid, dispel melanin, tyrosinase is inhibited to generate, there is a sterilization, cleaning skin effect, can anti-acne, nti-freckle improves Skin is dark yellow, moistens, moisturizing, weight reducing and other effects.
2. patchouli oil: there is special polymerization, this effect is the attribute to be scabbed by its convergence with promotion wound And come.This feature makes it be particularly helpful to promote wound because of the slack and undisciplined help Skin Cell regeneration of skin caused by excessively dieting It mouthful scabs, hence it is evident that the situation of dephlogistication improves the skin and various wounds and sore of coarse cracking.Also it can improve powder slightly Thorn, eczema, mycotic infection and scalp abnormal symptom.
3. cinnamon oil: antibiotic property is strong, there is strong analgesic activity, has the good effect of releiving for smooth muscle spasm.
4. Yilan caul-fat: Yilan is known as " flower in spending ", can stimulate adrenergic secretion, significant to alleviate depression, coke Consider and panic mood, loosen body & mind, open soul, therefore can make one to feel happy, the inspiring of creativity, enhancing it is self-confident and Self-respect.
5. rose oil: being known as " essential oil queen ", there is good beautifying skin-protection function, outer desalination spot is supported within energy Point promotes melanin to decompose, and improves dry skin, restores skin elasticity, and women is allowed to possess healthy flesh pale, full of elasticity Skin is the volatile oil for being suitable for female health.
Below by way of specific preferred embodiment combination effete test embodiment, invention is further described in detail, but the present invention It is not limited in embodiment below.Following degree is weight percent content.
Embodiment 1-3
A kind of anti-aging skin care product composition containing Moringa seed extract, by weight percentage, anti-aging combination Object is made of raw material components below, and wherein recipe ingredient and content are as shown in table 1 below.
The anti-aging skin care product composite formula raw material (weight %) containing Moringa seed extract of 1 embodiment 1-3 of table
The preparation method of the anti-aging skin care product composition containing Moringa seed extract of above-described embodiment 1-3, including with Lower processing step:
1) it adds water in water phase pot, opens stirring (50 revs/min), sequentially add 1,3-PD, Sodium Hyaluronate, gather Sodium glutamate, dipotassium glycyrrhizinate, sodium citrate are heated to 60 DEG C, dissolve fully transparent;
2) by ring five dimethyl silicone polymer, PEG-10 Polydimethylsiloxane, saualane, Wild soybean (GLYCINE SOJA) oil, tocopherol acetate, Moringa (MORINGA OLEIFERA) seed are oily, Pogostemon cablin (POGOSTEMON CABLIN) is oily, Cortex cinnamomi (CINNAMOMUM CASSIA) oil, Yilan (CANANGA ODORATA) caul-fat, caul-fat is successively for rose (ROSA RUGOSA) It is added in emulsion pot, opens stirring;
3) it vacuumizes, slowly sucks water phase material, open homogeneous (2000 revs/min), homogeneous 15 minutes.Start to drop Temperature;
4) plant extracts (german chamomile (CHAMOMILLA RECUTITA) flower extract, centella (CENTELLA is added ASIATICA) extract, Radix Glycyrrhizae (GLYCYRRHIZA URALENSIS) root extract, tea (CAMELLIA SINENSIS) leaf mention Object, polygonum cuspidate (POLYGONUM CUSPIDATUM) root extract, rosemary (ROSMARINUS OFFICINALIS) leaf is taken to extract Object, radix scutellariae (SCUTELLARIA BAICALENSIS) root extract) and skin conditioning agent (corn (ZEA MAYS) starch, crystallite Cellulose, sucrose, lactose, hydroxypropyl methyl cellulose, CI 77492), homogeneous 8 minutes;
5) it when being down to 40 DEG C, is added preservative (hexylene glycol, Phenoxyethanol, Chlorphenesin), 30 points of stirring (60 revs/min) The anti-aging skin care product composition with creams dosage form is made in clock after discharging.
The following are the contents of effete test embodiment part.
Effete test embodiment 1
1, the measurement of secondary ultra-oxygen anion free radical Scavenging activity:
The Tris-HCl buffer 4mL for taking 0.03mol/L pH=8.0, preheats 20min in 25 DEG C of water-baths.It adds The pyrogallol solution of the 20mmol/L of 1mL sample and 0.3mL after mixing, react 5min in 25 DEG C of water-baths, 6mol/L are added HCl solution 1.0mL terminate reaction.
Make reference with Tris-HCl buffer, absorbance value is surveyed at 299nm.Test sample is to resist described in embodiment 1 Aging composite skin care product, blank control substitute sample with the solvent of 1mL sample.According to formula 1) calculate clearance rate (D).Experiment The results are shown in Table 1.
Clearance rate formula (%) D=[1- (A2/A1)] × 100%1)
A1 is the absorbance value of blank control in formula;A2 is the absorbance value of sample.
Effete test embodiment 2
2, the measurement to the Scavenging activity of hydroxy radical:
2mmol/L FeSO is sequentially added in 25mL colorimetric cylinder43mL, 1mmol/L H2O23mL shakes up, and is subsequently added into 6mmol/L salicylic acid 3mL, shakes up, and takes out after 37 DEG C of heating water bath 15min, surveys its absorbance;It is separately added into certain density Prepare liquid shakes up, and continues heating water bath 15min, takes out and surveys its absorbance.Prepare liquid sample is anti-ageing described in embodiment 1 Old composite skin care product, blank control substitute sample with the solvent of 1mL sample.
Formula 2) it is clearance rate of the prepare liquid to carboxylic free radical (OH).Free radical scavenging activity experimental result is as shown in table 1.
OH clearance rate (%)=(A3-A2)/A1 × 100%2)
A1 is the absorbance value of reaction system before non-dosing product in formula;A2 is the absorbance value that sample removes system after OH; A3 is the absorbance value that system after OH is removed in blank control.
1 natural plant composition free radical scavenging activity result of table
Experimental project Clearance rate (%)
To superoxide anion scavenging effect 45.51
Scavenging effect to hydroxy radical 42.50
As can be seen from Table 1, anti-aging skin care product composition of the present invention has preferable free radical scavenging ability.
Effete test embodiment 3
3, delay senescence test (testing in vitro)
Test sample: embodiment 1, embodiment 2, embodiment 3, reference examples
Test method:
1) cause the fibroblast aging of human normal with hydrogen peroxide.
2) then the composite skin care product containing Moringa seed extract and reference examples are cultivated respectively.
3) they are carried out with the activity analysis of beta-galactosidase, this enzyme can accumulate in the cell of aging, therefore it It is the biological marker of an aging.
It is identified by histochemistal staining technique, and shoots and calculate the quantity of staining cell under the microscope.
Experimental result is after dioxygen water process, and the cell quantity of aging increases three times.It is added to moringa seeds extraction Object, embodiment 1 staining cell quantity reduce 50%.
The result shows that: the cosmetic composition containing Moringa seed extract of the embodiment of the present invention 1 can be effectively prevent carefully Born of the same parents' aging.
We have carried out same test to embodiment 2, embodiment 3, similar experimental result all occur, sufficiently prove Anti-aging skin care product composition of the invention has definite effect in terms of preventing cell senescence.
Effete test embodiment 4
4, product safety assessment (human skin patch test result)
Evaluation method:
1) tested material: embodiment 1, embodiment 2, embodiment 3;
2) negative control: reference examples;
3) subject: totally 35 people, male 15 people, 20 people of female the age 18~40 years old, meet subject and volunteer inclusion criteria.
4) spot test method: selecting qualified spot tester, with enclosed patch test method, by tested material about 0.02ml~ 0.025ml is applied in spot tester, and external application special adhesive tape is pasted on subject's forearm song side, removes tested material after 24 hours, in going Except 30min after tested material spot tester, dermoreaction is observed after impression disappearance, by " cosmetics health specification " (version in 2007) Dermoreaction grade scale records its result.
5) evaluation of result: reaction result is recorded by table 2 (skin adverse reaction grading standard).
The record result of 2 dermoreaction of table
Test result see the table below shown in 3.
3 cosmetic skin patch test results of table
The human skin patch test result of table 3 is shown:
In embodiment 1-3,35 subjects skins are all negative (grading system: 0 grade).According to " cosmetics are defended Raw specification " (version in 2007) human skin class patch test judgment criteria, sample is to human body without skin adverse reaction.
Experiment conclusion: the formula mildness of the embodiment of the present invention is very high, is completely suitable for the crowd of all kinds of skin quality.
The above described is only a preferred embodiment of the present invention, be not intended to limit the present invention in any form, therefore Without departing from the technical solutions of the present invention, to the above embodiments according to the technical essence of the invention any simply to repair Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.

Claims (8)

1. a kind of anti-aging skin care product composition containing Moringa seed extract, which is characterized in that by weight percentage, include Following raw material components:
Emollient 7-20%;
Moisturizer 5.05-10.5%;
Emulsifier 1.0-3.0%;
Plant extracts 0.5-1.0%;
Plants essential oil compound 0.5-5%;
Other skin conditioning agents 1.31-4.15%%;
Antioxidant 0.2-0.5%;
Preservative 0.2-0.5%;
Surplus is aqueous solvent.
2. the anti-aging skin care product composition containing Moringa seed extract as described in claim 1, it is characterised in that: the profit Skin agent is selected from ring five dimethyl silicone polymer, one kind of saualane or its mixing;The emulsifier is selected from PEG-10 poly dimethyl Siloxanes.
3. the anti-aging skin care product composition containing Moringa seed extract as described in claim 1, it is characterised in that: the plant Object extract is selected:
German chamomile flower extract;Gotu Kola P.E;Licorice root extract;Tea extract;Polygonum cuspidate root extract;Rosemary leave mentions Take object;Seven kinds of radix scutellariae root extract are the mixture of 1:1:1:1:1:1:1 according to mass ratio.
4. the anti-aging skin care product composition containing Moringa seed extract as described in claim 1, it is characterised in that: the guarantor Humectant is selected from one of 1,3- propylene glycol, Sodium Hyaluronate or its mixing;
The antioxidant is selected from one of tocopherol acetate, vitamin C, vitamin E or its mixing;
The preservative includes one kind or its mixing of hexylene glycol, Phenoxyethanol, Chlorphenesin.
5. the anti-aging skin care product composition containing Moringa seed extract as described in claim 1, it is characterised in that: the plant Object essential oil compound is selected from:
5 kinds of seed oil of Moringa oleigera, patchouli oil, cinnamon oil, Java Cananga Oil, rose oil components are the mixed of 1:1:1:1:1 according to mass ratio Close object.
6. the anti-aging skin care product composition containing Moringa seed extract as described in claim 1, it is characterised in that: it is described its His skin conditioning agent includes Wild soybean oil 0.01-0.3%;Dipotassium glycyrrhizinate 0.05-0.3%;Polyglutamic acid sodium 0.05-0.3%; Sodium citrate 0.2-0.5%;Cornstarch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl methyl cellulose and CT77492 it is mixed Close object 0.1-0.5%.
7. a kind of anti-aging skin care product composition containing Moringa seed extract, which is characterized in that by weight percentage, be by Following raw material components composition:
Ring five dimethyl silicone polymer 5-15%, 1,3- propylene glycol 5-10%, PEG-10 Polydimethylsiloxane -3%, saualane 2-5%, Wild soybean oil 1-3%, plant extracts (include german chamomile flower extract, Gotu Kola P.E, licorice root extract, tea Leaf extract, polygonum cuspidate root extract, rosemary leaf extract, radix scutellariae root extract) 0.5-1.0%, Sodium Hyaluronate 0.05- 0.5%, dipotassium glycyrrhizinate 0.05-0.3%, polyglutamic acid sodium 0.05-0.3%, sodium citrate 0.2-0.5%, tocopheryl acetate Ester 0.2-0.5%, seed oil of Moringa oleigera 0.1-1.0%, patchouli oil 0.1-1.0%, cinnamon oil 0.1-1.0%, Yilan caul-fat 0.1- 1.0%, rose oil 0.1-1.0%, skin conditioning agent (include cornstarch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl first Base cellulose, CT77492) 0.1-0.5%, preservative (including hexylene glycol, Phenoxyethanol, Chlorphenesin) 0.2-0.5%, surplus For water.
8. the anti-aging skin care product composition containing Moringa seed extract as claimed in claim 7, it is characterised in that: described anti- Aging composite skin care product is made by following processing step:
1) it adds water in water phase pot, opens stirring (50 revs/min), sequentially add 1,3-PD, Sodium Hyaluronate, polyglutamic Sour sodium, dipotassium glycyrrhizinate, sodium citrate are heated to 60 DEG C, dissolve fully transparent;
2) by ring five dimethyl silicone polymer, PEG-10 Polydimethylsiloxane, saualane, Wild soybean oil, tocopherol acetate, Seed oil of Moringa oleigera, patchouli oil, cinnamon oil, Yilan caul-fat, rose oil sequentially add in emulsion pot, open stirring;
3) it vacuumizes, slowly sucks water phase material, open homogeneous (2000 revs/min), homogeneous 15 minutes, start to cool down;
4) plant extracts (german chamomile flower extract, Gotu Kola P.E, licorice root extract, tea extract, polygoni cuspidati,radix is added Extract, rosemary leaf extract, radix scutellariae root extract) and skin conditioning agent (cornstarch, microcrystalline cellulose, sucrose, cream Sugar, hydroxypropyl methyl cellulose, CI 77492), homogeneous 8 minutes;
5) it when being down to 40 DEG C, is added preservative (hexylene glycol, Phenoxyethanol, Chlorphenesin), stirring (60 revs/min) 30 minutes, Discharging.
CN201910871506.2A 2019-09-16 2019-09-16 A kind of anti-aging skin care product composition containing Moringa seed extract Pending CN110420150A (en)

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FR3113452A1 (en) * 2020-06-22 2022-02-25 Laboratoire Astelia Mosquito Repellent Scent
CN114425030A (en) * 2022-02-16 2022-05-03 广州萃普生物科技有限公司 Plant extract composition, preparation method and application thereof
CN114594177A (en) * 2022-01-25 2022-06-07 中国科学院武汉植物园 Method for screening anti-aging active ligand
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FR3113452A1 (en) * 2020-06-22 2022-02-25 Laboratoire Astelia Mosquito Repellent Scent
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