CN110403578A - A kind of heat conducting device measuring skin flap of rats nerve recovery - Google Patents

A kind of heat conducting device measuring skin flap of rats nerve recovery Download PDF

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Publication number
CN110403578A
CN110403578A CN201910818179.4A CN201910818179A CN110403578A CN 110403578 A CN110403578 A CN 110403578A CN 201910818179 A CN201910818179 A CN 201910818179A CN 110403578 A CN110403578 A CN 110403578A
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China
Prior art keywords
heat conductive
conductive rod
fixed station
skin flap
heat conducting
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Pending
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CN201910818179.4A
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Chinese (zh)
Inventor
庄跃宏
郑海波
马启明
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Fujian Medical University
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Fujian Medical University
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Priority to CN201910818179.4A priority Critical patent/CN110403578A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4041Evaluating nerves condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/006Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Finger-Pressure Massage (AREA)

Abstract

The present invention relates to a kind of heat conducting devices for measuring skin flap of rats nerve recovery, it include a fixed station, the positioning plate of an arch is installed on the fixed station, perforation offers port before and after the positioning plate, the strip-shaped hole protruded into for heat conductive rod is offered with side at the top of the positioning plate, the strip-shaped hole extends into port, the heat conductive rod is connected through conducting wire with a heating device, the heat conducting device of the measurement skin flap of rats nerve recovery is simple and reasonable, can validity test rat postoperative skin whether have the shrinkage area of shrinkage reaction and shrinkage position and the variation of shrinkage intensity.

Description

A kind of heat conducting device measuring skin flap of rats nerve recovery
Technical field
The present invention relates to a kind of heat conducting devices for measuring skin flap of rats nerve recovery.
Background technique
Skin is the maximum organ of human body, and having prevents foreign bodies from invading, and adjusts body temperature, the function such as pain, touching, temperature sensation Energy.Also often because of soft tissue, underlying nerve damage caused by tumour, burn, knife wound etc..Clinically, skin flap transplantation is treatment soft tissue Damage unique method.Flap (skin flap) is with self-blood supply, the tissue block comprising skin histology.Tissue lacks The reparation and reconstruction of damage, histoorgan reconstruction etc. require flap.Mainly there are two aspects for postoperative skin flap transplanting evaluation: shape is repaired Multiple, sensory recovery.With the development of medicine, prominent question has been not present in the former, but the latter is often not fully up to expectations, gives patient Daily life brings puzzlement.For the flap of denervation due to a lack of neurotrophy and innervation, flap can be thinning, is prone to wear brokenly It bursts, the dry tarnish of appearance, numbness etc., and vasomotor disturbances in the flap of total denervation, lead to tissue edema, skin Skin anti-infection ability is low.In denervation infection flap, the area of septicopyemia lesion and soft tissue oedema is also dramatically increased.Cause This, flap sensory recovery has extremely important effect and meaning in Clinical Surgery.Flap sensory recovery is evaluated mainly by two Part forms: morphological observation, Behavior test.Rat dorsum skin layering respectively epidermis, skin corium, subcutaneous tissue, Fascia under sarcolemma (skeletal muscle) and sarcolemma.
With regard to there are many deficiencies in current flap nerve recovery judgment technology, i.e., it can not accurately judge sensory recovery degree, Mechanical hyperalgesia stimulates in the prior art, and postoperative rat experiment model reaction is unobvious, different time points, different researcher's operations Dynamics change greatly, can not criterion and quantity.
Summary of the invention
In view of the deficiencies in the prior art, technical problem to be solved by the invention is to provide a kind of measurement skin flap of rats nerves The heat conducting device of recovery, be not only simple in structure rationally, and can validity test rat postoperative skin whether have shrinkage reaction And shrinkage position shrinkage area and shrinkage intensity variation, and then judge journey is restored and restored to the feeling of flap whether Degree.
In order to solve the above-mentioned technical problem, the technical scheme is that a kind of heat for measuring skin flap of rats nerve recovery Conduction device includes a fixed station, and the positioning plate of an arch is installed on the fixed station, and perforation is opened before and after the positioning plate Equipped with port, the strip-shaped hole protruded into for heat conductive rod is offered with side at the top of the positioning plate, which extends into logical In mouthful, the heat conductive rod is connected through conducting wire with a heating device.
Further, the positioning plate offers limiting slot vertically at nearby rear end, plugs vertically in the limiting slot There is limit gate, the tail end which offers the card slot of arch from bottom to top to cooperate rat;Limit gate Middle part offers an aperture, and front and back, which is run through, in the aperture is inserted with gag lever post.
Further, the fixed station is rectangular, and the left and right sides is bolted with two binding posts respectively, every binding post side The opening stretched out for rat four limbs is offered on positioning plate.
Further, it is provided with head limiting device on the fixed station of the positioning front edge of board, the head limiting device packet The limited post that left and right two is vertically arranged on fixed station is included, two limited posts are symmetrically disposed on fixed station front end left and right sides, two limits Position column is equipped with a position-limited round rod in the equal left and right horizontal of place near to the upper end, and is spirally connected from top to bottom through the first bolt above limited post Enter limited post and contact with position-limited round rod to be positioned, the fixed station and two limited post lower end contact positions offer positioning groove, institute It states positioning groove and runs through fixed station and front and back extension, limited post and fixed station up and down through passing through the second bolt of positioning groove from bottom to top It is spirally connected.
Further, the heating device upper surface is equipped with temperature indicator, and temperature indicator side is installed with thermally conductive Stick places block, and the heat conductive rod places block upper surface and is extended with hanging rod upward vertically, and rear hanging rod is bent downwards, then curved upward Folding forms an opening up U-shaped hanging groove and mounts for heat conductive rod.
Further, it is socketed with shell outside to tail end in the middle part of the heat conductive rod, the bending of heat conductive rod head end is in 90 degree, and idle is led It is articulated in U-shaped hanging groove in the middle part of hot pin.
Further, the heating device front end face is provided with power switch, and power switch side is provided with thermoregulation knob.
Compared with prior art, the invention has the following advantages: by the present apparatus, heat conductive rod is passed through into the flap pair Whether the strip-shaped hole contact stimulus normal side and art side skin answered, observation skin have shrinkage reaction and shrinkage position or shrinkage area Variation, shrinkage intensity, judge whether the feeling of flap is restored and recovery extent as indication, and can be postoperative in rat Different time repeats, and carries out horizontal and vertical comparison according to experimental comparison group, can quantitatively calculate flap in each time The necrosis rate of node quantifies nerve recovery degree;The present invention is a kind of auxiliary assessment approach as nerve regneration, for experiment Standardization, the quantization of values and the evaluation of sensory nerve recovery extent provide preferable realization device and method.
The present invention will be further described in detail with reference to the accompanying drawings and detailed description.
Detailed description of the invention
Fig. 1 is the organigram that the embodiment of the present invention removes heating device;
Fig. 2 is the top view of heating device in the embodiment of the present invention;
Fig. 3 is the main view of heating device in the embodiment of the present invention;
Fig. 4 is fixed station and limited post attachment structure schematic diagram in the embodiment of the present invention;
Fig. 5 is the part drawing that gate is limited in the embodiment of the present invention.
In figure: 1- fixed station, 2- positioning plate, 3- port, 4- strip-shaped hole, 5- heating device, 6- limiting slot, 7- limit lock Door, 8- card slot, 9- aperture, 10- gag lever post, 11- binding post, 12- opening, 13- head limiting device, 14- limited post, 15- limit Circle of position bar, the first bolt of 16-, 17- positioning groove, the second bolt of 18-, 19- temperature indicator, 20- heat conductive rod place block, and 21- is hung Bar, 22-U type hanging groove, 23- shell, 24- power switch, 25- thermoregulation knob, 26- heat conductive rod, 27- heat conductive rod interface.
Specific embodiment
To make the foregoing features and advantages of the present invention clearer and more comprehensible, special embodiment below, and cooperate attached drawing, make detailed Carefully it is described as follows.
As shown in Fig. 1 ~ 5, a kind of heat conducting device measuring skin flap of rats nerve recovery, includes a fixed station 1, described Be installed with the positioning plate 2 of an arch on fixed station, perforation offers port 3 before and after the positioning plate, at the top of the positioning plate with Side offers the strip-shaped hole 4 protruded into for heat conductive rod 26, which extends into port, the heat conductive rod through conducting wire with One heating device 5 is connected.
In embodiments of the present invention, the positioning plate offers limiting slot 6 vertically at nearby rear end, in the limiting slot It is inserted with limit gate 7 vertically, which offers the card slot 8 of arch from bottom to top to cooperate rat end to end End;An aperture 9 is offered in the middle part of limit gate, through gag lever post 10 is inserted with, the limiting slot is settable for front and back in the aperture Have multiple, adapts to various sizes of rat so that limit gate plugs different limiting slot.
In embodiments of the present invention, the fixed station is rectangular, and the left and right sides is spirally connected respectively, and there are two binding posts 11, often The opening 12 stretched out for rat four limbs is offered on the positioning plate of binding post side, rat four limbs stretch out four respectively in positioning A opening, and rat four limbs are subjected to bind with corresponding binding post through cotton rope, complete the positioning of rat four limbs.
In embodiments of the present invention, it is provided with head limiting device 13 on the fixed station of the positioning front edge of board, the head Limiting device includes the limited post 14 that left and right two is vertically arranged on fixed station, and two limited posts are symmetrically disposed on fixed station front end Left and right sides, two limited posts are equipped with a position-limited round rod 15 in the equal left and right horizontal of place near to the upper end, and through the first spiral shell above limited post Bolt 16, which is screwed into limited post from top to bottom and contacts with position-limited round rod, to be positioned, the fixed station and two limited post lower end contact positions Positioning groove 17 is offered, the positioning groove runs through fixed station up and down and front and back extends, and limited post and fixed station are worn from bottom to top The second bolt 18 for crossing positioning groove is spirally connected;The height for being highly below positioning plate vertically of two limited posts, in favor of to rat head Portion is limited.
In embodiments of the present invention, the heating device upper surface is equipped with temperature indicator 19, temperature indicator side It is installed with heat conductive rod and places block 20, the heat conductive rod places block upper surface and is extended with hanging rod 21, the rear vertical court of hanging rod upward vertically Lower bending, then bend upward, it forms an opening up U-shaped hanging groove 22 and is mounted for heat conductive rod.
In embodiments of the present invention, it is socketed with shell 23 outside to tail end in the middle part of the heat conductive rod, the bending of heat conductive rod head end is in 90 degree, idle heat conductive rod middle part is articulated in U-shaped hanging groove, and heat conductive rod head end is the circular flat that diameter is 5mm, and calculating is facilitated to connect Contacting surface product.
In embodiments of the present invention, the heating device front end face is provided with power switch 24, the setting of power switch side There is thermoregulation knob 25.
A kind of working method for the heat conducting device measuring skin flap of rats nerve recovery, sequentially includes the following steps: and pulls out first Gag lever post out takes out limit gate, unscrews the first and second bolt, unscrew binding post, and it is fixed to be then packed into postoperative rat from port In the plate of position, rat four limbs is stretched out into opening, and rat four limbs are subjected to bind with corresponding binding post through cotton rope respectively, screw and connect Terminal is fixed, and then will further limit to rat in limit gate insertion limiting slot and gag lever post is inserted into aperture, can It is moved forward and backward the suitable fixed position of position selection of the limited post above positioning groove and screws the second bolt and fix, then left and right Two position-limited round rod are moved horizontally, make the equal apical grafting of two position-limited round rod at rat head both ends, the first bolt is then screwed and completes pair The positioning of rat;It is then turned on power switch, the heat conductive rod interface 27 opened up on heat conductive rod and heating device front end face is connect, Heat conductive rod and heating device are electrically connected, after placed from heat conductive rod and remove heat conductive rod on block, pass through thermoregulation knob and observed temperature Thermally conductive nose is then protruded into strip-shaped hole and contacted with Rat Epidermis and tested, and observed by display register heat conductive rod temperature Whether skin has the variation of shrinkage reaction and shrinkage position or shrinkage area.
The present invention is not limited to above-mentioned preferred forms, anyone can show that other are each under the inspiration of the present invention The heat conducting device of the measurement skin flap of rats nerve recovery of kind form.All equivalent changes done according to scope of the present invention patent With modification, it is all covered by the present invention.

Claims (7)

1. a kind of heat conducting device for measuring skin flap of rats nerve recovery, it is characterised in that: include a fixed station, the fixation The positioning plate of an arch is installed on platform, perforation offers port before and after the positioning plate, and the positioning plate top is equal with side The strip-shaped hole protruded into for heat conductive rod is offered, which extends into port, and the heat conductive rod is filled through conducting wire and a heating It sets connected.
2. a kind of heat conducting device for measuring skin flap of rats nerve recovery according to claim 1, it is characterised in that: described Positioning plate offers limiting slot vertically at nearby rear end, is inserted with limit gate vertically in the limiting slot, the limit gate Lower end offers the card slot of arch from bottom to top to cooperate the tail end of rat;An aperture is offered in the middle part of limit gate, this is small Front and back, which is run through, in hole is inserted with gag lever post.
3. a kind of heat conducting device for measuring skin flap of rats nerve recovery according to claim 1, it is characterised in that: described Fixed station be it is rectangular, the left and right sides is bolted with two binding posts respectively, is offered on the positioning plate of every binding post side for big The opening that mouse four limbs stretch out.
4. a kind of heat conducting device for measuring skin flap of rats nerve recovery according to claim 1, it is characterised in that: described It positions and is provided with head limiting device on the fixed station of front edge of board, which includes that left and right two is vertically arranged in admittedly Determine the limited post on platform, two limited posts are symmetrically disposed on fixed station front end left and right sides, and two limited posts are in place near to the upper end left and right water It is flat to be equipped with a position-limited round rod, and be screwed into limited post from top to bottom through the first bolt above limited post and contacted with position-limited round rod It is positioned, the fixed station and two limited post lower end contact positions offer positioning groove, and the positioning groove runs through fixed station up and down And front and back extends, limited post and fixed station are spirally connected through passing through the second bolt of positioning groove from bottom to top.
5. a kind of heat conducting device for measuring skin flap of rats nerve recovery according to claim 1, it is characterised in that: described Heating device upper surface is equipped with temperature indicator, and temperature indicator side is installed with heat conductive rod and places block, and the heat conductive rod is put It sets block upper surface and is extended with hanging rod upward vertically, rear hanging rod is bent downwards, then is bent upward, and an opening up U is formed Type hanging groove is mounted for heat conductive rod.
6. a kind of heat conducting device for measuring skin flap of rats nerve recovery according to claim 1 or 5, it is characterised in that: It is socketed with shell outside to tail end in the middle part of the heat conductive rod, the bending of heat conductive rod head end is in 90 degree, is articulated in the middle part of idle heat conductive rod U-shaped In hanging groove.
7. a kind of heat conducting device for measuring skin flap of rats nerve recovery according to claim 1, it is characterised in that: described Heating device front end face is provided with power switch, and power switch side is provided with thermoregulation knob.
CN201910818179.4A 2019-08-30 2019-08-30 A kind of heat conducting device measuring skin flap of rats nerve recovery Pending CN110403578A (en)

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Application Number Priority Date Filing Date Title
CN201910818179.4A CN110403578A (en) 2019-08-30 2019-08-30 A kind of heat conducting device measuring skin flap of rats nerve recovery

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Application Number Priority Date Filing Date Title
CN201910818179.4A CN110403578A (en) 2019-08-30 2019-08-30 A kind of heat conducting device measuring skin flap of rats nerve recovery

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1915186A (en) * 2006-09-05 2007-02-21 徐杰 Fixing device for experiment of stimulates of senses of pain and heat
CN102811676A (en) * 2010-01-05 2012-12-05 库罗医疗公司 Medical heating device and method with self-limiting electrical heating element
CN202699111U (en) * 2012-08-22 2013-01-30 胡斯旺 Novel real-time viewing window for animal tissue
CN203458493U (en) * 2013-09-12 2014-03-05 深圳先进技术研究院 Rat clamping device
CN204072054U (en) * 2014-08-11 2015-01-07 江毅 A kind of multi-functional superficial sensation examining instrument
EP2974656A1 (en) * 2014-07-14 2016-01-20 Universität Zürich Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner
CN105592788A (en) * 2013-03-06 2016-05-18 塞罗拉公司 Form factors for the multi-modal physiological assessment of brain health
CN205626168U (en) * 2016-03-10 2016-10-12 首都医科大学附属北京中医医院 Rat fixing device
CN108637419A (en) * 2018-04-18 2018-10-12 北京四方继保自动化股份有限公司 Intelligent electric iron equipment and the method operated with its control welding

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1915186A (en) * 2006-09-05 2007-02-21 徐杰 Fixing device for experiment of stimulates of senses of pain and heat
CN102811676A (en) * 2010-01-05 2012-12-05 库罗医疗公司 Medical heating device and method with self-limiting electrical heating element
CN202699111U (en) * 2012-08-22 2013-01-30 胡斯旺 Novel real-time viewing window for animal tissue
CN105592788A (en) * 2013-03-06 2016-05-18 塞罗拉公司 Form factors for the multi-modal physiological assessment of brain health
CN203458493U (en) * 2013-09-12 2014-03-05 深圳先进技术研究院 Rat clamping device
EP2974656A1 (en) * 2014-07-14 2016-01-20 Universität Zürich Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner
CN106714686A (en) * 2014-07-14 2017-05-24 苏黎世大学 Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner
CN204072054U (en) * 2014-08-11 2015-01-07 江毅 A kind of multi-functional superficial sensation examining instrument
CN205626168U (en) * 2016-03-10 2016-10-12 首都医科大学附属北京中医医院 Rat fixing device
CN108637419A (en) * 2018-04-18 2018-10-12 北京四方继保自动化股份有限公司 Intelligent electric iron equipment and the method operated with its control welding

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Application publication date: 20191105