CN110337325A - System and method for generating dry particl from liquid solution - Google Patents
System and method for generating dry particl from liquid solution Download PDFInfo
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- CN110337325A CN110337325A CN201880014206.6A CN201880014206A CN110337325A CN 110337325 A CN110337325 A CN 110337325A CN 201880014206 A CN201880014206 A CN 201880014206A CN 110337325 A CN110337325 A CN 110337325A
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- 239000006193 liquid solution Substances 0.000 title claims abstract description 36
- 238000000034 method Methods 0.000 title claims description 14
- 239000002245 particle Substances 0.000 claims abstract description 82
- 238000001035 drying Methods 0.000 claims abstract description 38
- 238000003860 storage Methods 0.000 claims description 10
- 239000011358 absorbing material Substances 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 9
- 230000015572 biosynthetic process Effects 0.000 claims description 8
- 230000005672 electromagnetic field Effects 0.000 claims description 8
- 230000005855 radiation Effects 0.000 claims description 8
- 238000011084 recovery Methods 0.000 claims description 5
- 238000009938 salting Methods 0.000 claims description 4
- 230000007613 environmental effect Effects 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 description 29
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 10
- 239000000443 aerosol Substances 0.000 description 9
- 230000008859 change Effects 0.000 description 7
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- 230000033001 locomotion Effects 0.000 description 7
- 230000005684 electric field Effects 0.000 description 6
- 230000008020 evaporation Effects 0.000 description 6
- 238000001704 evaporation Methods 0.000 description 6
- 210000000981 epithelium Anatomy 0.000 description 5
- 230000035876 healing Effects 0.000 description 5
- 238000010438 heat treatment Methods 0.000 description 5
- 239000011780 sodium chloride Substances 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 4
- 208000006673 asthma Diseases 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 238000002425 crystallisation Methods 0.000 description 3
- 230000008025 crystallization Effects 0.000 description 3
- 230000005611 electricity Effects 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 239000003595 mist Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 230000001133 acceleration Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 208000023504 respiratory system disease Diseases 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 201000003883 Cystic fibrosis Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 239000000090 biomarker Substances 0.000 description 1
- 201000009267 bronchiectasis Diseases 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
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- 230000007407 health benefit Effects 0.000 description 1
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- 210000003928 nasal cavity Anatomy 0.000 description 1
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 1
- 210000003695 paranasal sinus Anatomy 0.000 description 1
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B13/00—Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices
- B07B13/10—Grading or sorting solid materials by dry methods, not otherwise provided for; Sorting articles otherwise than by indirectly controlled devices using momentum effects
Abstract
The present invention provides a kind of equipment for generating the dry particl of predetermined size from liquid solution, which includes droplet generator, drying unit and partial size selector.Partial size selector includes deflected channel and movable sprinklers, and wherein movable sprinklers can be moved along deflected channel to collect the particle of required size.
Description
Technical field
The present invention relates to generate dry particl, and more specifically, doing from size needed for salting liquid generation from liquid solution
Salt particle.
Background technique
In recent years, the quantity of the anaphylactia, reaction and other severe complications that are generated due to drug therapy is had
Sizable growth.Therefore, clinician encourages exploitation without drug treatment.Salt mist therapy is exactly such a method, should
Method is to imitate the treatment mode of the mineral salt hole micro climate in controlled environment.The source artificial salt (NaCl) aerosol (aerosol)
(such as, salt fog chamber (halochamber), salt wetting system or inhalator) has become a kind of both sides in mineral salt aerosol source
Just again cheap alternative.Natural and artificial salt aerosol source for treatment can all improve the quality of living.
Salt aerosol improves the quality of atmosphere in many ways, including antiviral prevention and improvement participate in intense physical activity
People cardiovascular system and spiritual nervimotion (psychoneuromotor) system functional parameter.
There are also multiple health benefits for salt mist therapy, comprising: improves cardio-pulmonary function and spiritual neuromotor function, enhancing is immune
System improves asthma and phlegm is discharged from respiratory tract.Some clinical tests 75% Severe Asthma case, 85% it is slight
With moderate asthma case and 97% chronic bronchitis, achieve in bronchiectasis and cystic fibrosis case it is preferable
Clinical effectiveness (A.V.Chervinskaya, Journal of Aerosol Medicine, 1995,8,3).
Currently, salt room (salt fog chamber) is usually used to the salt hole micro climate of creation simulation；However, such treatment is simultaneously
Be not suitable for the consumer in home environment.In this case, salt aerosol generator is available.
Most of salt aerosol generators deliver liquid drop to consumer, these drops have unlike dry salt particle
Effect.Currently, inhalable dry NaCl particle (diameter D≤5 μm) utilize the preparation and delivering for passing through Diskus (DPI).Dry powder
Preparation process is complicated, and is expensive for the encapsulating of each dosage.Limited delivering method and high price limits
The possible application of salt therapy, this may prevent certain user (such as, the asthmatics in family, the patient in hospital, upper body
Educate the sportsman in the student and training court of class) use.Diskus is typically also in this way, Diskus has in this way
One additional drawback: user needs sharply to suck suitably to manage dosage.
Due to physical stability problem (such as, the moisture pick-up properties of salt particle), in-situ preparation inhalable (D≤5 μm) is simultaneously
And NaCl aerosol is done with certain challenge in stable (D≤2.5 μm) in terms of air force.By considering that dry NaCl particle exists
The optimum diameter of penetration depth and deposition efficiency in people's lung, dry salt particle should be lower than 2 μm.In general, only having less than 1 μm
The particle of diameter can deep enough alveolar region；However, the dry NaCl particle (D < 2 μm) of most of suckings can be deposited on respiratory tract.
Consumer with different respiratory diseases may need different size sum number purpose salt particles.For example, for
The problems in epithelium healing, diameter are that several microns of salt particle can reach impacted position；However, for asking in downtake
Topic, only the lesser salt particle of partial size can move to impacted position.In addition, some positions need nanoscale particle.
Currently, available solution be not based on the state of an illness of user select to user deliver particle size mechanism.
Summary of the invention
The present invention is defined by the claims.
According to the example of aspect according to the invention, provide a kind of for generating dry of predetermined size from liquid solution
Grain equipment, wherein equipment include:
Droplet generator, wherein droplet generator is adapted to be from liquid solution and generates drop；
Drying unit, wherein drying unit is adapted to be from drop formation dry particl；And
Partial size selector, wherein partial size selector include:
Deflected channel, wherein dry particl is deflected in deflected channel according to its size；And along deflected channel can
Moving nozzle, wherein movable sprinklers are adapted to be the dry particl for collecting predetermined size.
This equipment generates the dry particl of predetermined size from liquid solution.Droplet generator makes liquid solution nebulize, from
And form drop in the air in equipment.Drop is then supplied to drying unit, which makes liquid from drop
Evaporation, to generate dry particl, these dry particls are then supplied to partial size selector.In partial size selector, particle is based on
Its size is moved a certain distance along deflected channel.Movable sprinklers are moved to the travel distance of required partial size along deflected channel,
Then, particle particle at the travel distance is collected.
Nozzle according to circumstances can be moved to collect various sizes of particle.In this way it is possible to execute from liquid
The dry particl of liquid solution in-situ preparation and delivering predetermined size.
In one embodiment, liquid solution includes salting liquid.Therefore, equipment can generate various sizes of salt particle with
For salt therapy.Biggish salt particle can be used to the state of an illness in the epithelium healing for the treatment of user, and lesser particle is used to
Treat the state of an illness in downtake.
In some embodiments, droplet generator includes at least one of ultrasonic transducer and compressed air unit.
Drop can be generated by ultrasonic transducer or by compressed air.These methods can generate different sizes
Drop；However, the time long enough that the drop only with the diameter less than 5 μm will remain suspended in air, to be mentioned
Supply drying unit.
In arrangement, drying unit includes temperature control unit.
In this way, the temperature in drying unit can increase, and drop evaporation and dry particl is promoted to be formed.In addition, logical
The temperature for crossing the air in control drying unit, can reduce the relative humidity in equipment, to further promote in drop
Hydrone evaporation.
In some designs, temperature control unit includes at least one of the following: peltier (Peltier) equipment, electricity
Hinder heater, the source of infrared radiation and microwave radiation source.
Therefore, in order to control the temperature in drying unit, temperature control unit can be using individual equipment or equipment
Combination.
In one embodiment, drying unit includes absorbing material, which, which is adapted to be, reduces in drying unit
Opposite and absolute humidity.
By further decreasing the humidity in drying unit, promote drop evaporation.In this way, dry is generated from solution
Time needed for grain is likely to reduced, to allow to reduce the size of drying unit, and therefore, reduces the size of equipment.
In some arrangements, movable sprinklers collect diameter less than 2 μm, preferably dry particl of the diameter less than 1 μm.
In this way it is possible to select the particle of appropriate size for deep lung treatment.
In one embodiment, movable sprinklers include rotatable outlet.
It is thereby possible to select dry particl leaves the flow direction of equipment.For example, in breathing equipment, dry particl should be by
It is directed towards the nose or mouth of user.
In some embodiments, drying unit further comprises charge unit, which, which is adapted to be, makes dry particl
Electrification, and in a further embodiment, deflected channel includes electromagnetic field generator.
In this way, drying unit can make dry particl charged, to allow equipment further to control the fortune of dry particl
It is dynamic.By generating electromagnetic field, when charged particle movement passes through deflected channel, Lorentz force is applied to charged particle.?
Magnetic component will change the direction of travel of particle, and the electric component of field will change the total distance of particle traveling.
In arrangement, equipment further comprises flow generator.
By providing air-flow, dry particl can be made to leave equipment with required speed.For example, this can be used to dissipate particle
Cloth is indoors in environment.It sharply sucks in addition, this may reduce user to receive the needs of the dry particl of suitable dosage.
In one embodiment, equipment further comprises storage unit, which is adapted to be storage liquid solution.
In some embodiments, equipment further comprises recovery unit, and wherein recovery unit, which is adapted to be, makes not to be collected
Particle be moved to storage unit from partial size selector.
Recovery unit prevents the particle packing being not used by equipment, and allows to reuse particle, rather than locates
Reason falls particle.
According to the example of aspect according to the invention, provide a kind of for generating dry of predetermined size from liquid solution
Grain system, wherein system include:
Sensor, wherein sensor is adapted to be build environment data；
Above equipment；And
Control unit, the control unit are connected to equipment and sensor, and wherein control unit is adapted to be based on environment number
According to controlling equipment.
It can be controlled by using the environmental data from sensor by providing controller and sensor, equipment.Example
Such as, if a sensor senses that the user in facility environment (such as, in the identical room) coughs, then controller can be controlled
Control equipment generates dry particl and selects the dry particl with optimum size to treat cough.Controller also can receive to use by oneself
The input at family is to control equipment.
According to the example of aspect according to the invention, a kind of dry particl that predetermined size is generated from liquid solution is provided
Method, method include:
Drop is generated from liquid solution；
From drop formation dry particl；
Size based on dry particl deflects dry particl along deflected channel；And
Nozzle is set to be moved into the position of deflected channel to collect the dry particl of predetermined size.
Detailed description of the invention
Describe example of the invention in detail now with reference to attached drawing, in the accompanying drawings:
Fig. 1 shows the schematic diagram of the equipment for generating dry particl from liquid solution；
Fig. 2 shows granule densities to two charts of time；
Fig. 3 shows one embodiment of drying unit shown in FIG. 1；
Fig. 4 shows one embodiment of partial size selector shown in FIG. 1；
Fig. 5 shows an example of the travel distance of determining particle；
Fig. 6 shows the other example of the travel distance of determining particle；
Fig. 7 shows the movement of particle；And
Fig. 8 shows method of the invention.
Specific embodiment
The present invention provides it is a kind of for from liquid solution generate dry particl equipment, the equipment include droplet generator,
Drying unit and partial size selector.Partial size selector includes deflected channel and movable sprinklers, and wherein movable sprinklers can edge
The mobile particle to collect required size of deflected channel.
Fig. 1 shows equipment 10, which includes droplet generator 20, and wherein droplet generator is adapted to be from liquid
Solution (such as, salting liquid) generates drop 22.Droplet generator can be using ultrasonic transducer or compressed air so as to from liquid
Liquid solution generates drop.In the case where ultrasonic transducer, liquid solution can be provided to container, and the pedestal of the container is at least
Partly formed by ultrasonic transducer.In activation, ultrasonic transducer fast vibration, so that the liquid solution mist formation in container
Shape forms drop in container air above.Alternatively, compressed air can be conducted through liquid solution container or
Stream.The high speed of compressed air sprays into liquid solution in the air in droplet generator, to generate the liquid of liquid solution
Drop.Method can be independent or be used in combination with each other.Liquid solution can be provided to droplet generator from storage unit, this is deposited
Storage unit can form the part of equipment 10 or be provided separately.
Only the drop 22 of some size (diameter is less than 5 μm) remains suspended in the sufficiently long time in air, to reach
The drying unit 30 of equipment.The size of drop can be controlled by changing the concentration of liquid solution.Lower concentration will be led
Cause lesser and more evenly drop.
Drop 22 is provided to drying unit 30, which transfers from drop formation dry particl 32.Drop can be with
Air-flow by passing through equipment is provided to drying unit.Air-flow can by internal gas flow generator (such as, fan) or
It is generated by external source (such as, user's sucking of proximity device).In either case, drop 22 all can be around
Drying unit 30 is provided to when the flowing of air.
Temperature control unit 34 can be arranged in drying unit 30 to control local temperature.Temperature control unit can
To include at least one of the following: peltier device, resistance heater, the source of infrared radiation and microwave radiation source.
The peltier device for serving as heat pump being used in combination with heat exchanger (such as, cooling fin group) can be used for cooling and include
The surrounding air of drop, to reduce relative humidity.Generation heat from heat exchanger can be further used for heating through drying
Air to increase saturation pressure, while also keeping absolute vapour pressure low.Suspending drops are in through air that is dry and heating.
Low-humidity environment can speed up H2O hydrone is evaporated from drop, to generate dry particl.
Peltier device can be used in combination with other temperature control unit (such as, the source of infrared radiation).In this feelings
Under condition, dry particl of the diameter less than 1 μm can be generated, it is meant that particle can reach the downtake of user.Using appropriate excellent
Change, such as, using the liquid solution of various concentration, the power of the source of infrared radiation and treatment, can obtain with required range
The dry particl of size.
Fig. 2 shows granule density c to two charts of time t.Top chart 50 is shown does not answer in infrared therapeutic
The distribution of particle size when for drop, and bottom chart 51 shows the particle size when infrared therapeutic is applied to drop
Distribution.
First line 52 of top chart 50 shows particle of the diameter less than or equal to 10 μm with time change
Concentration.Article 2 line 53, Article 3 line 54 and the fourth line 55 respectively illustrate diameter less than or equal to 5 μm, 2.5 μm and 1 μ
This identical relationship of the particle of m.Double line indicates that the particle of only minimum overlapping classes is visible.For example, at top
In chart, first line, Article 2 line and Article 3 line are overlapped after past 3000s, it is meant that after such time, are not had
It is greater than 2.5 μm of particle with the presence of diameter.
In the chart 51 of lower section, first line 56 indicates the overlapping of particle of the diameter equal to or less than 10 μm and 5 μm
Classification, Article 2 line 57 indicate that diameter is equal to or less than 2.5 μm of particle, and Article 3 line 58 indicate diameter be equal to or
Particle less than 1 μm.As that can see from the bottom chart for depicting the scene including infrared therapeutic, only diameter be less than or
Particle of the person equal to 1 μm is visible over time, become；However, diameter is less than or equal to 2.5 μm in the chart of top
Particle concentration stablize after it is still visible.It therefore, include that can make in temperature control unit directly by infrared heater
Particle of the diameter less than or equal to 1 μm can be produced unanimously.
Dry particl is then supplied to partial size selector 40, which includes deflected channel 42 and removable spray
Mouth 44.
When entering deflected channel 42, dry particl 32 is deflected based on its size.Larger particles meeting with larger quality
Traveling short distance 45；The biggish distance 46 however, lesser particle can advance.Movable sprinklers 44 can be moved to required size
Particle estimation travel distance 47.In this way, equipment can generate from liquid solution, collect and be distributed predetermined size
Dry particl.In the case where needing dry particl to reach the downtake of user, movable sprinklers can be moved to collect diameter about 1
μm dry particl；However, movable sprinklers can be moved to collect diameter about it is only necessary to treat epithelium healing
2 μm of dry particl, the distance that this dry particl can be shorter along deflected channel traveling because of its size and quality.
Equipment 10 can be set in systems, which also comprises sensor and controller.Controller can be with hand
The operation of dynamic and automatic two kinds of operating modes.In a manual mode, the required running parameter of user input equipment, including liquid solution
Concentration, dry particl size, respiratory disorder type, delivering direction and duration.In automatic mode, sensor is used to monitor
The local environment of equipment, user exist and the biomarker of known breath tract disease.Controller can be generated based on sensor
The required running parameter of equipment is arranged in data automatically.For example, sound transducer can detecte the sound of user's cough.In response to
This, control unit can will be sized to several microns of diameter needed for dry salt particle, so that movable sprinklers are moved to phase
Position is answered to collect these particles, and delivers them to consumer to clear up their epithelium healing.
Fig. 3 shows one embodiment 30 ' of drying unit 30 shown in FIG. 1.In this embodiment, drying unit includes
Multiple temperature control units, multiple temperature control unit are positioned along at the discrete positions of dry channel.Temperature control is single
Member can be single sequential cells shown in FIG. 1, or may include any number of discrete heating unit.
In addition, drying unit 30 ' further comprises absorbing material 60, which is adapted to be reduction drying unit
Interior humidity.Absorbing material (for example, zeolite) can absorb H from the air around drop2O molecule, and reduce dry channel
Local humidity.Low-humidity environment, which can aid in, accelerates H2O molecule is evaporated from drop itself.Water absorbed in absorbing material
Dividing can be evaporated by the air stream of surrounding.
In general, the moisture content of surrounding air is lower than the air in dry channel.Surrounding air can also be by such as resistance
Heater wire heating, to promote moisture to evaporate from absorbing material.Surrounding air can be guided to flow through absorbing material, thus
Minimize the water content of surrounding air.
Humidity in drying unit 30 ' can be controlled by heating unit 34 (such as, peltier device) and absorbing material 60.
By controlling the local humidity of drying unit, the drop 22 of generation can be with rapid crystallization at solid particle 32.Gu the crystallization of particle/
The time scale of change is as unit of millisecond.Specifically, the smaller salt drop for diameter less than 1 μm, in 70% relative humidity
Under, the time is within 1 millisecond.This short crystallization time means that phase transformation can occur along short transport path, it is meant that
In the case where the generation for not sacrificing dry particl, the size of drying unit be can reduce, and therefore, the overall dimensions of equipment can subtract
It is small.For example, being 5 μm of salt drop for diameter under 70% relative humidity, evaporation time is less than 30ms.It means that right
It can be 30mm in the length of the air velocity of 1m/s, drying unit.
Fig. 4 shows one embodiment 40 ' of partial size selector 40 shown in FIG. 1.In this embodiment, movable sprinklers
Further comprise rotatable outlet 62, the rotatable outlet 62 can be oriented to when collected dry particl leaves equipment
Required side boots up collected dry particl.For example, equipment can be arranged to close to be subjected in the first example cough and
The user of sinus block is subjected in the second example.In the first example, rotatable outlet 62 is oriented to towards user's mouth,
To ensure that dry particl as much as possible reaches epithelium healing；However, rotatable outlet is oriented to towards user in the second example
Nose to ensure that dry particl is advanced through nasal cavity and nasal sinus.For example, this point is especially heavy if equipment is incorporated into mask
It wants.
Rotatable outlet 62 can also have especially with the equipment in the air-conditioning system in the multiple rooms for being connected to building
Relationship.Position (for example, inputted by manual user or be automatically sensed indicated) based on user, rotatable outlet can be by
For dry particl is directed in occupied space.
In the case that charge unit in drying unit 30 of the dry particl 32 by equipment 10 is charged, partial size selector 40 '
It further comprise electromagnetic field generator 64.By establishing electromagnetic field in partial size selector, electrically charged particle can change them along inclined
Turn the propagation path in channel 42.Electromagnetic field can for example by apply a voltage to be located at deflected channel opposite side electrode come
It is generated.By the accurate selection of the intensity to electromagnetic field, the size of dry particl can be more accurately distinguished between.
In this arrangement, the motor behavior of three power control electrically charged particles.First power is gravity: G=g*m, wherein g table
Show the acceleration generated due to gravity, and m is the quality of dry particl.Due to the effect of gravity, compared with lesser particle
Compared with the distance that bulky grain can be shorter along deflected channel traveling.
Caused by other power are the electric and magnetic fields created due to electromagnetic field generator.When electrically charged particle movement passes through electricity
When magnetic field, electrically charged particle undergoes Lorentz force,F=m* (dv/ dt)=q* (E+V×B), wherein q is the net charge of dry particl,E
It is electric field strength,VIt is the speed of dry particl, andBIt is magnetic field strength.Both gravitation and electric field force can change salt particle
Speed.Magnetic field force can be such that particle deflects.Based on the interaction of gravity and electromagnetic force on electrically charged particle, of certain sizes
The travel distance of grain can be readily calculated.Therefore, the position of movable sprinklers can be determined that easily collect it is specific
The particle of size.
Partial size selector may further include recovery unit 66, which is adapted to be reception and is not moved
The dry particl that nozzle 44 is collected.The particle not being collected can be moved away from due to the air-flow caused by the electric field or power
Partial size selector, such as it is moved to storage unit.In this way, prevent the particle packing not being collected in partial size selector
In, and dry particl will not be wasted, because they can be used again in the process.
The travel distance of particle can determine in many ways.For example, Fig. 5 shows particle 32 with initial velocity V traveling
The deflected channel 42 for being D by diameter.In this case, it is assumed that particle enters channel from center.It is generated across deflected channel
The electric field of intensity E.Density, quality, diameter and the charge of dry particl are respectively defined as ρ, m, R and q.Charge q and initial velocity v
It can be measured by charge unit or pre-defined.For spheric granules, the relationship between quality m and radius R is given as:
In this case, electric field force and gravity control the movement 70 of particle by following equation:Wherein,It is the static(al) on particle, andIt is the acceleration generated because of gravity.So
Afterwards, the travel distance L of particle can be calculated by following equation:
The distance can be calculated by equipment or controller, needed for being collected according to particle along the travel distance of deflected channel
The particle of size.
Fig. 6 shows the other example for the particle 32 advanced along deflected channel.In this case, in variable and Fig. 5
The variable of definition is identical；However, being applied in deflected channel by the magnetic field for the intensity B for intersecting (cross) expression.Particle is in electricity
Movement under both field and magnetic field is complicated.In order to simplify scene, we can be considered electric field force and generate with because of gravity
Dynamic balance example, it is meant that:
If magnetic field B, perpendicular to the initial velocity V of particle, particle can move in a circle 72.The radius of circular motion is logical
Following equation is crossed to provide:The circular motion 72 of particle is further depicted as in Fig. 7.
Therefore, the travel distance L of particle is defined as:
Fig. 8 shows method 80 of the invention.
In step 82, drop is generated from liquid solution.Drop can be by ultrasonic transducer or compressed air list
Member generates.
In step 84, dry particl is from drop formation.By controlling the temperature and humidity of the local environment of drop, promote
Into evaporation, thus from drop formation dry particl.
In step 86, dry particl is deflected based on its size along deflected channel.Compared with lesser particle, bulky grain
Can advance shorter distance.
In step 88, nozzle is moved to along the position of deflected channel, to collect the dry particl of predetermined size.
By the research to attached drawing, disclosure and appended claims, those skilled in the art are required by implementation
Other modifications of the disclosed embodiments are understood that and realized while the invention of protection.In the claims, word " packet
Include " be not excluded for other elements perhaps step and indefinite article " one " or "one" be not excluded for plural form.Mutually different
The pure fact for being recited in mutually different dependent certain measures do not illustrate that the combination of these measures can not be by advantageously
It uses.Any element symbol in claims is not necessarily to be construed as limitation range.
Claims (15)
1. a kind of equipment for generating the dry particl (32) of predetermined size from liquid solution, wherein the equipment includes:
Droplet generator (20), wherein the droplet generator, which is adapted to be from the liquid solution, generates drop (22)；
Drying unit (30), wherein the drying unit is adapted to be from the drop formation dry particl；And
Partial size selector (40), wherein the partial size selector includes:
Deflected channel (42), wherein the dry particl is deflected in the deflected channel according to its size；And
Along the movable sprinklers (44) of the deflected channel, wherein the movable sprinklers, which are adapted to be, collects predetermined size
Dry particl.
2. equipment according to claim 1, wherein the liquid solution includes salting liquid.
3. equipment according to any one of the preceding claims, wherein the droplet generator includes ultrasonic transducer and pressure
At least one of contracting air element.
4. equipment according to any one of the preceding claims, wherein the drying unit includes temperature control unit
(34)。
5. equipment according to claim 4, wherein the temperature control unit (34) includes at least one of following: amber
Ear note equipment, resistance heater, the source of infrared radiation and microwave radiation source.
6. equipment according to any one of the preceding claims, wherein the drying unit includes absorbing material (60), institute
It states absorbing material (60) and is adapted to be the humidity reduced in the drying unit.
7. equipment according to any one of the preceding claims, wherein the movable sprinklers (44) collect diameter less than 2 μ
M, preferably dry particl of the diameter less than 1 μm.
8. equipment according to any one of the preceding claims, wherein the movable sprinklers include rotatable outlet
(62), the rotatable outlet (62) is adapted to be the direction that control particle leaves the deflected channel.
9. equipment according to any one of the preceding claims, wherein the drying unit further comprises charge unit,
The charge unit, which is adapted to be, charges the dry particl.
10. equipment according to claim 9, wherein the deflected channel includes electromagnetic field generator (64).
11. equipment according to any one of the preceding claims, wherein the equipment further comprises flow generator.
12. equipment according to any one of the preceding claims, wherein the equipment further comprises storage unit, it is described
Storage unit is adapted to be the storage liquid solution.
13. equipment according to claim 12, wherein the equipment further comprises recovery unit (66), wherein described return
Receipts unit is adapted to be the particle for making not to be collected and is moved to the storage unit from the partial size selector.
14. a kind of system for generating the dry particl of predetermined size from liquid solution, wherein the system comprises:
Sensor, wherein the sensor is adapted to be build environment data；
Equipment according to any one of the preceding claims；And
Control unit, described control unit are connected to the equipment and the sensor, and wherein described control unit is adapted to be
The equipment is controlled based on the environmental data.
15. a kind of for generating the method (80) of the dry particl of predetermined size from liquid solution, which comprises
(82) drop is generated from the liquid solution；
From the drop formation (84) dry particl；
Size based on the dry particl makes the dry particl deflect (86) along deflected channel；And
Nozzle mobile (88) is set to collect the dry particl of predetermined size to the position along the deflected channel.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2017/000197 | 2017-02-28 | ||
| CN2017000197 | 2017-02-28 | ||
| EP17169880.6A EP3401005A1 (en) | 2017-05-08 | 2017-05-08 | Systems and method for generating dry particles from a liquid solution |
| EP17169880.6 | 2017-05-08 | ||
| PCT/EP2018/054969 WO2018158337A1 (en) | 2017-02-28 | 2018-02-28 | Systems and method for generating dry particles from a liquid solution |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110337325A true CN110337325A (en) | 2019-10-15 |
| CN110337325B CN110337325B (en) | 2022-03-18 |
Family
ID=61569248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880014206.6A Active CN110337325B (en) | 2017-02-28 | 2018-02-28 | System and method for generating dry particles from a liquid solution |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN110337325B (en) |
| WO (1) | WO2018158337A1 (en) |
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| US5722479A (en) * | 1994-07-11 | 1998-03-03 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Directional electrostatic accretion process employing acoustic droplet formation |
| US5868305A (en) * | 1995-09-25 | 1999-02-09 | Mpm Corporation | Jet soldering system and method |
| WO2001091525A2 (en) * | 2000-05-22 | 2001-11-29 | The Regents Of The University Of California | High-speed fabrication of highly uniform ultra-small metallic microspheres |
| CN1486215A (en) * | 2000-11-09 | 2004-03-31 | ����Τ�����ʹ�˾ | Spheres and method of forming a plurality of spheres |
| CN204699418U (en) * | 2014-11-24 | 2015-10-14 | 南通东概念新材料有限公司 | A kind of simple grain footpath spraying droplets drying tower |
| CN105102342A (en) * | 2012-11-01 | 2015-11-25 | 精密阀门有限公司 | Free flow aerosol valve |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2253353A1 (en) * | 1972-10-31 | 1974-07-11 | Knapsack Ag | SORTING DEVICE |
| US4801411A (en) * | 1986-06-05 | 1989-01-31 | Southwest Research Institute | Method and apparatus for producing monosize ceramic particles |
| US6491737B2 (en) * | 2000-05-22 | 2002-12-10 | The Regents Of The University Of California | High-speed fabrication of highly uniform ultra-small metallic microspheres |
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- 2018-02-28 WO PCT/EP2018/054969 patent/WO2018158337A1/en active Application Filing
- 2018-02-28 CN CN201880014206.6A patent/CN110337325B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5722479A (en) * | 1994-07-11 | 1998-03-03 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Directional electrostatic accretion process employing acoustic droplet formation |
| US5868305A (en) * | 1995-09-25 | 1999-02-09 | Mpm Corporation | Jet soldering system and method |
| WO2001091525A2 (en) * | 2000-05-22 | 2001-11-29 | The Regents Of The University Of California | High-speed fabrication of highly uniform ultra-small metallic microspheres |
| CN1486215A (en) * | 2000-11-09 | 2004-03-31 | ����Τ�����ʹ�˾ | Spheres and method of forming a plurality of spheres |
| CN105102342A (en) * | 2012-11-01 | 2015-11-25 | 精密阀门有限公司 | Free flow aerosol valve |
| CN204699418U (en) * | 2014-11-24 | 2015-10-14 | 南通东概念新材料有限公司 | A kind of simple grain footpath spraying droplets drying tower |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018158337A1 (en) | 2018-09-07 |
| CN110337325B (en) | 2022-03-18 |
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