CN110327057A - A kind of multiple determination strip - Google Patents
A kind of multiple determination strip Download PDFInfo
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- CN110327057A CN110327057A CN201910691818.5A CN201910691818A CN110327057A CN 110327057 A CN110327057 A CN 110327057A CN 201910691818 A CN201910691818 A CN 201910691818A CN 110327057 A CN110327057 A CN 110327057A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
- A61B5/150061—Means for enhancing collection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150358—Strips for collecting blood, e.g. absorbent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15101—Details
- A61B5/15103—Piercing procedure
- A61B5/15105—Purely manual piercing, i.e. the user pierces the skin without the assistance of any driving means or driving devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
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- Heart & Thoracic Surgery (AREA)
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- Optics & Photonics (AREA)
- Dermatology (AREA)
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a kind of multiple determination strips, from bottom to up successively include: substrate, are used to support the strip；Conductive layer, including multi-group electrode, wherein every group of electrode is for detecting a kind of corresponding physical signs；Insulating layer is covered on the conductive layer, and the corresponding multi-group electrode opens up multiple groups aperture to expose corresponding electrode, and the region of the multiple groups aperture overlapping corresponding with multi-group electrode is multiple reaction zones；Layers of two-sided is covered on the insulating layer, and corner location thereon opens up jagged, and the notch is located at injection port of the one end of corner as the strip, and the other end is connected to the multiple reaction zone；Hydrophilic membrane is covered in layers of two-sided, for promoting blood to enter each reaction zone from the injection port using siphonic effect, the present invention can solve multiple determination in the prior art it is existing time-consuming, speed is slow, and blood using amount is big, problem at high cost.
Description
Technical field
The present invention relates to bio-sensing strip technology fields, more particularly to a kind of multiple determination strip.
Background technique
With the development of the times, people's lives level is become better and better, but due to the accelerating rhythm of life, the pressure of people
Power is also increasing, and the number that body is in inferior health is also more and more.And the people to live under this sub-health state, very
It is easy to suffer from the diseases such as hyperglycemia, high lithemia, hyperlipidemia, hypertension, these diseases are exactly the " Metabolic syndrome that people are frequently referred to
Sign ".These diseases are all that metabolism aspect is abnormal caused, and it is interactional that the connection between them, which is very close,.Such as one
Personal uric acid is high, it is possible he blood glucose and blood lipid be also problematic in that.
Hyperlipidemia, which can arrive, leads to liver's function damage；Hyperglycemia will lead to eye ground capillary and hemangioma occurs；
High lithemia can cause urarthritis.Long-term hyperlipidemia, hyperglycemia, high lithemia can cause cirrhosis, artery sclerosis, pain
Wind, the diseases such as rheumatic arthritis.Therefore, this kind of chronic disease is very important index in people's daily life, therefore,
The health status of oneself is grasped in time, and the detection of early stage and in time control find the state of an illness compared with the later period, carries out drug therapy, show
It obtains even more important.
Now on the market, blood glucose can much be monitored by having, the instrument and strip of uric acid and blood lipid, but the examination of every kind of model
Item may only all detect a kind of index.And the patient for needing to monitor many indexes is it is necessary to prepare a plurality of instruments and strip, this
Sample monitoring there is that time-consuming, and speed is slow, and blood using amount is big, the problems such as at high cost.
Summary of the invention
In order to overcome the deficiencies of the above existing technologies, purpose of the present invention is to provide a kind of multiple determination strip,
With time-consuming existing for solution in the prior art multiple determination, speed is slow, and blood using amount is big, problem at high cost.
In view of the above and other objects, the present invention proposes a kind of multiple determination strip, successively include: from bottom to up
Substrate is used to support the strip；
Conductive layer, including N group electrode, wherein every group of electrode is for detecting a kind of corresponding physical signs；
Insulating layer is covered on the conductive layer, and to open up multiple groups aperture corresponding to expose for the corresponding multi-group electrode
Electrode, the region of the multiple groups aperture overlapping corresponding with multi-group electrode are multiple reaction zones；
Layers of two-sided is covered on the insulating layer, and corner location thereon opens up jagged, and the notch is located at corner
Injection port of the one end as the strip, the other end of the notch is connected to the multiple reaction zone；
Hydrophilic membrane is covered in layers of two-sided, for promoting blood to enter respectively from the injection port using siphonic effect
Reaction zone.
Preferably, the N group electrode that the conductive layer is corresponded on the insulating layer opens up N to aperture correspondingly to expose correspondence
Electrode, each pair of aperture for realizing a physical signs detection.
Preferably, aperture is arranged close to the injection port by the N.
It preferably, is the background electricity in every group of electrode in the aperture reaction zone of the relatively close injection port in each pair of aperture
Pole is relatively distant from the aperture reaction zone of the injection port as the working electrode in every group of electrode.
Preferably, the notch of the layers of two-sided has N number of split channel, and N number of split channel respectively correspondingly covers
The N of the insulating layer is placed on in aperture, is led to forming the N number of sample introduction being connected between the injection port and multiple reaction zones
Road.
Preferably, the notch, which is cut into, is gradually broadened by injection port width and is divided into N number of sample intake passage to each
The shape of reaction zone.
Preferably, the injection port width is 0.5~2mm.
Preferably, Yu Suoshu insulating layer and/or the edge of the base correspond to the injection port and cut corresponding fillet.
Preferably, the hydrophilic membrane corresponds to the sample intake passage equipped with gas vent.
Preferably, each sample intake passage being corresponded on the hydrophilic membrane, one gas vent is at least set.
Compared with prior art, carbon is starched printing by carrying out silk-screen using halftone by a kind of multiple determination strip of the present invention
Conductive conductive layer is formed on to substrate, includes multi-group electrode in conductive layer, every group of electrode is for detecting a kind of corresponding life
Index is managed, is then separated electrode in forming insulating layer on conductive layer by screen painting, and described in corresponding on insulating layer
Multi-group electrode opens up multiple groups aperture to expose corresponding electrode, then will set double faced adhesive tape jaggy on the insulating layer, notch position
Injection port of the one end as the strip in corner, the other end of the notch are connected to the multiple reaction zone, finally will
Hydrophilic film is pasted on insulating layer by layers of two-sided, promotes blood to enter sample intake passage using siphonic effect, to realize one kind
The strip of detectable many indexes, the multiple determination strip realized through the invention can monitor many indexes, separately have and use blood
Amount is few, and sample introduction is fast, is easy to find accurately injection port, the few advantage of consumptive material, the monitoring convenience and high-efficiency for chronic disease and cost-effective, can
The experience of client is promoted well.
Detailed description of the invention
Fig. 1 is a kind of decomposition diagram of multiple determination strip of the present invention；
Fig. 2 is the schematic diagram of conductive layer 20 in the specific embodiment of the invention；
Fig. 3 is the schematic diagram of insulating layer 30 in the specific embodiment of the invention；
Fig. 4 is the schematic diagram of layers of two-sided 40 in the specific embodiment of the invention；
Fig. 5 is the schematic diagram of hydrophilic membrane 50 in the specific embodiment of the invention.
Specific embodiment
Below by way of specific specific example and embodiments of the present invention are described with reference to the drawings, those skilled in the art can
Understand further advantage and effect of the invention easily by content disclosed in the present specification.The present invention can also pass through other differences
Specific example implemented or applied, details in this specification can also be based on different perspectives and applications, without departing substantially from
Various modifications and change are carried out under spirit of the invention.
Fig. 1 is a kind of decomposition diagram of multiple determination strip of the present invention.As shown in Figure 1, as shown in Figure 1, the present invention
A kind of multiple determination strip successively includes substrate 10, conductive layer 20, insulating layer 30, layers of two-sided 40 and parent from bottom to up
Water film 50.
Wherein, substrate 10 are used to support the strip, and in the specific embodiment of the invention, substrate 10 is suitable using PET sheet etc.
The material for closing carbon film printing is printed using carbon film as the skeleton of strip and provides the support of certain degree of hardness.
Conductive layer 20, including N group electrode, wherein every group of electrode is for detecting a kind of corresponding physical signs, specifically, N
Background electrode D1, D3 that electrode includes N number of working electrode Wi (i=1,2 ... N) and is formed into a loop therewith are organized, is had in the present invention
In body embodiment, N=3 is taken, (theoretically i can take arbitrary integer, as long as strip structure can accommodate down, the present invention is or not i=1~3
As limit), i.e., conductive layer 20 includes 3 working electrode Wi and forms the background electrode of current loop with each working electrode Wi
D1 and D3, wherein D1 is the background electrode of W1, and D3 is the background electrode that W2 and W3 is shared, and D1 and W1 forming circuit are for detecting
The first physical signs, D3 and W2, W3 be respectively formed circuit for detect second, the third physical signs, the present invention tool
In body embodiment, corresponding N group electrode judges electrode A i (i=1,2 ... N) in also setting up N number of sample introduction degree on conductive layer, respectively into
Sample degree judges that the effect of electrode A i is mainly used for judging sample introduction degree, and is not involved in the detection of each physical signs project, herein
It will not go into details.Preferably, be additionally provided with impedance electrodes D2 on conductive layer 20, impedance electrodes D2 can with each working electrode W1, W2,
W3 is formed into a loop for detecting impedance.It should be noted that one kind that the distribution of 20 top electrode of conductive layer is only embodied here
Situation, the present invention is not limited thereto.
Insulating layer 30 is covered on conductive layer 20, and the N group electrode on corresponding conductive layer 20 opens up the aperture of N group to expose pair
The region of the electrode answered, the N group aperture overlapping corresponding with N group electrode forms multiple groups reaction zone.Specifically, the insulating layer
The N group electrode that the conductive layer 20 is corresponded on 30 opens up N to aperture correspondingly to expose corresponding working electrode Wi and background electricity
Pole D1, D3 cover an aperture HBi, work that is, for each physical signs detection project on corresponding background electrode
An aperture is covered on electrode Wi, two apertures form one group of reaction zone, and insulating layer 30 is used for the electrode (carbon film of conductive layer 20
Conducting wire) keep apart while reducing the influence of external environment, only in tapping under the connection of blood in detecting electrode and common electrical
Interpolar forms current path, and the region that the electrode of aperture and conductive layer is overlapped is corresponding reaction zone, i.e., each pair of aperture with lead
The region of the electrode overlapping of electric layer is respectively the operating current reaction zone and background current reaction zone to detecting electrode, insulating layer
30 aperture exposes the electrode of conductive layer 20, could make sample that can enter reaction zone from tapping in this way and envelope
Electrode, it should be noted that, the relative position between 20 electrode of aperture and conductive layer of insulating layer does not have particular requirement, permits in structure
Perhaps as close as possible to injection port under the premise of, therefore, in the specific embodiment of the invention, the N of insulating layer 30 to aperture HBi,
HWi is correspondingly arranged in the group electrode front end N close to injection port, be background electrode D1 in the aperture reaction zone of relatively close injection port,
D3 adds reagent, can enhance conductive capability for obtaining background current in the opening area where the electrode；Be relatively distant from into
It is working electrode Wi in the aperture reaction zone of sample mouth, it is each pair of to realize a finger for obtaining the operating current of corresponding detection project
Target detection corresponds to N group electrode (work electricity as shown in figure 3, insulating layer 30 is the insulating oil layer of ink designed by certain shapes
Pole and background electrode) the pairs of aperture being sized is formed to expose corresponding detecting electrode, for opening simultaneously electrode isolation
Reduce the influence of external environment, only forms electricity between working electrode and corresponding background electrode under the connection of blood in tapping
Logical circulation road.
Layers of two-sided 40 is covered on insulating layer 30, and corner location thereon opens up jagged 401, and the notch is located at
Injection port 402 of the one end of corner as the strip, the other end of the notch 401 are connected to the multiple reaction zone,
In the specific embodiment of the invention, the notch is the notch with N number of split channel, which respectively correspondingly covers
The N of the insulating layer is placed on in aperture, N number of sample intake passage between injection port and multiple reaction zones is connected to formation,
In the specific embodiment of the invention, the notch is cut into one from narrow to wide and is divided into N number of sample intake passage to each reaction zone
Shape obtains blood sample by its injection port 402 for being located at corner one end, and enters each reaction zone by N number of sample intake passage, at this
In invention specific embodiment, the injection port 402 is located at the upper right corner of layers of two-sided 40, and width is 0.5~2mm, two-sided
Notch on glue-line 40 constitutes sample intake passage for each reaction zone to be connect with injection port.
Preferably, for user convenience, the edge of Yu Suoshu insulating layer 30 and/or the base 10 it is corresponding it is described into
Sample mouth is cut corresponding fillet (301,101), the effect of these fillets, first is that the finger for positioning user, withstands on finger
Finger is positioned convenient for user on fillet and strip (because when acquisition blood sample, needs user first to puncture finger, then will go out on finger
The position of blood withstands on injection port, and strip size is smaller, and such fillet can facilitate user to position), second is that on double-sided adhesive
Opening constitutes overall clearance with fillet, is individually open bigger in void ratio layers of two-sided, blood is made to be easier to be inhaled into.
Hydrophilic membrane 50 is covered in layers of two-sided 40, and the hydrophilic membrane of gas vent 501 is had for certain shapes, is used
In using siphonic effect promote blood enter each sample intake passage.In the specific embodiment of the invention, as shown in figure 5, hydrophilic film 50
It is pasted on dielectric ink 30 by double-sided adhesive 40, a gas vent 501 is at least arranged in corresponding each sample intake passage, in sample introduction
Process quickly the air in channel is drained, reduce the resistance of sample introduction.
Embodiment
Skeleton using the substrate 10 of PET sheet as strip carries out silk-screen using halftone and carbon slurry is printed onto shape on PET sheet
At conductive conductive layer 20, N group detecting electrode is formed on conductive layer 20, wherein every group of detecting electrode is for detecting corresponding one
Kind of physical signs, N group electrode include N number of working electrode Wi (the present embodiment N is 3, i.e. i=1,2,3) and background electrode D1,
D3, wherein D1 is the background electrode of W1, and D3 is the background electrode that W2 and W3 is shared, and D1 and W1 forming circuit are for detecting first
Kind physical signs, D3 and W2, W3 are respectively formed circuit, for detecting second, the third physical signs, then pass through halftone again
Dielectric ink is printed on formation insulating layer 30 on detecting electrode by printing, being separated with will test electrode, N group is corresponded on insulating layer 30
Electrode opens up N group aperture HBi, HWi (N=3, i.e., 3 groups) for being sized to leak out corresponding electrode, and aperture HBi, HWi are corresponding
Being set to N group electrode front end is background electrode in the injection port for being located at corner, the aperture reaction zone of relatively close injection port,
For obtaining background current, being relatively distant from the aperture reaction zone of injection port is working electrode, for obtaining corresponding detection project
Operating current, each pair of aperture realizes the detection of an index, and the region of the N group aperture overlapping corresponding with N group electrode is N number of
Reaction zone；Then double faced adhesive tape is used as to layers of two-sided 40 on dielectric ink again, the corner location in layers of two-sided 40 opens up
There is the notch with N number of split channel, which is located at injection port of the one end of corner as strip, N number of split channel point
The N of the insulating layer is not covered in accordingly to the N in aperture, being connected between the injection port and multiple reaction zones with formation
A sample intake passage, the notch are cut into one from narrow to wide and are divided into the shape of N number of sample intake passage to each reaction zone, finally
Hydrophilic film is pasted on insulating layer by layers of two-sided, each sample intake passage is corresponded in hydrophilic film and is provided with gas vent, with benefit
Promote blood to enter each sample intake passage with siphonic effect, after blood sample enters each channel, reacts shape with the enzyme solution on electrode hole
Convert micro-current to the test value that can be read at micro-current, then by detecting instrument, after posting hydrophilic film, by slitting and
Roller shear obtains complete multiple determination strip.
Multiple determination principle of the invention is as follows:
When blood sample enters insulation via each sample intake passage after entering each sample intake passage by notch from injection port instillation
The aperture (namely reaction zone) of layer can all have blood sample entrance, the reagent generationization on blood sample and electrode in two pairs of apertures
Reaction is learned, under the premise of detecting electrode of the detecting instrument to strip conductive layer applies voltage, electric current can be generated on electrode loop；
After the completion of sample introduction, detecting instrument, as operating current, is adopted by the electric current on reaction zone automatic collection working electrode
Collect the electric current on background electrode as background current, after getting two current values, calling is stored in advance in detecting instrument
Calculating function to calculate concentration value, and finally concentration value is shown on the display screen of instrument.
Compared with prior art, the multiple determination strip of the present invention has the advantages that
1, there is N number of sample intake passage, N kind index can be detected simultaneously, be 3 kinds in the embodiment of the present invention；
Need blood volume few 2. strip has, theoretically primary test can be completed in 1.5ul；
Strip of the present invention needs blood sample few related with the sample intake passage design of strip, in embodiments of the present invention, entire sample introduction
The floor space (area of injection port, reaction zone and sample intake passage) in channel only has 16.6mm2, the height of sample intake passage is only 0.09mm
(thickness for being equal to double-sided adhesive)；The sample intake passage volume formed in this way only has 1.5mm3(1.5ul)；And strip of the invention
Structure can measure three kinds of indexs, be equivalent to measure the blood sample that each index only needs 0.5ul in this way, and on current market
Strip needed for blood sample be both greater than 0.5ul substantially, therefore, strip structure of the present invention reduces the blood sample of test.
3. strip sample introduction speed is fast, three channels can be filled blood sample simultaneously substantially；
Firstly, the injection port width of strip of the present invention is 1mm, with the entrance of blood sample, the width in channel is increasing, this
Sample can greatly reduce the resistance of blood sample flowing, when blood sample flows to the maximum width in channel, and by sample division to three small
Channel can guarantee the blood sample of three passage aisles substantially in this way while be filled；Secondly, having one in the top in three small channels
Air in channel can be drained quickly in the process of sample introduction, reduce the resistance of sample introduction by a gas vent, can be quickly by blood sample
Suck sample intake passage.
4. strip design sample introduction, user from angle can more be easy to find injection port accurately.
5. the ingenious science of strip carbon film conductor layouts, each detecting electrode are arranged side by side, public electrode forming circuit is shared, and
By the oblique design of reaction zone, while injection port being designed to the consumption that rapidoprint is greatly reduced positioned at corner, final finished
Sample width only has 8.4mm
In conclusion carbon slurry is printed onto substrate by carrying out silk-screen using halftone by a kind of multiple determination strip of the present invention
It is upper to form conductive conductive layer, it include multi-group electrode in conductive layer, every group of electrode is used to detect a kind of corresponding physical signs,
Then electrode is separated in forming insulating layer on conductive layer by screen painting, and electric in corresponding to the multiple groups on insulating layer
Pole opens up multiple groups aperture to expose corresponding electrode, then will set double faced adhesive tape jaggy on the insulating layer, and notch is located at corner
Injection port of the one end as the strip, the other end of the notch is connected to the multiple reaction zone, finally by hydrophilic film
It is pasted on insulating layer by layers of two-sided, promotes blood to enter sample intake passage using siphonic effect, it is a kind of detectable to realize
The strip of many indexes, the multiple determination strip realized through the invention can monitor many indexes (the present embodiment is three kinds),
Separately have blood using amount few, sample introduction is fast, be easy to find accurately injection port, the few advantage of consumptive material, monitoring convenience and high-efficiency for chronic disease and
It is cost-effective, the experience of client can be promoted well.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.Any
Without departing from the spirit and scope of the present invention, modifications and changes are made to the above embodiments by field technical staff.Therefore,
The scope of the present invention, should be as listed in the claims.
Claims (10)
1. a kind of multiple determination strip, which is characterized in that successively include: from bottom to up
Substrate is used to support the strip；
Conductive layer, including multi-group electrode, wherein every group of electrode is for detecting a kind of corresponding physical signs；
Insulating layer is covered on the conductive layer, and the corresponding multi-group electrode opens up multiple groups aperture to expose corresponding electrode,
The region of the multiple groups aperture overlapping corresponding with multi-group electrode is multiple reaction zones；
Layers of two-sided is covered on the insulating layer, and corner location thereon opens up jagged, and the notch is located at the one of corner
The injection port as the strip is held, the other end is connected to the multiple reaction zone；
Hydrophilic membrane is covered in layers of two-sided, for promoting blood to enter each reaction from the injection port using siphonic effect
Area.
2. a kind of multiple determination strip as described in claim 1, it is characterised in that: correspond to the conduction on the insulating layer
The N group electrode of layer opens up N to aperture correspondingly to expose corresponding electrode, each pair of aperture for realizing a physical signs inspection
It surveys.
3. a kind of multiple determination strip as claimed in claim 2, it is characterised in that: the N is to aperture close to the sample introduction
Mouth setting.
4. a kind of multiple determination strip as claimed in claim 3, it is characterised in that: in each pair of aperture it is relatively close it is described into
It is the background electrode in every group of electrode in the aperture reaction zone of sample mouth, it is every for being relatively distant from the aperture reaction zone of the injection port
Working electrode in group electrode.
5. a kind of multiple determination strip as claimed in claim 2, it is characterised in that: the notch of the layers of two-sided has N
A split channel, N number of split channel are respectively correspondingly covered in the N of the insulating layer in aperture, are connected to being formed
N number of sample intake passage between the injection port and multiple reaction zones.
6. a kind of multiple determination strip as claimed in claim 5, it is characterised in that: the notch is cut by injection port
Width gradually broadens and is divided into the shape of N number of sample intake passage to each reaction zone.
7. a kind of multiple determination strip as claimed in claim 6, it is characterised in that: the injection port width is 0.5~
2mm。
8. a kind of multiple determination strip as described in claim 1, it is characterised in that: Yu Suoshu insulating layer and/or the base
The edge of layer corresponds to the injection port and cuts corresponding fillet.
9. a kind of multiple determination strip as described in claim 1, it is characterised in that: the hydrophilic membrane corresponds to the sample introduction
Channel is equipped with gas vent.
10. a kind of multiple determination strip as claimed in claim 9, it is characterised in that: corresponding each on the hydrophilic membrane
A gas vent is at least arranged in sample intake passage.
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