CN110279499A - The hydrophilic silicon stent of antibacterial - Google Patents
The hydrophilic silicon stent of antibacterial Download PDFInfo
- Publication number
- CN110279499A CN110279499A CN201810207317.0A CN201810207317A CN110279499A CN 110279499 A CN110279499 A CN 110279499A CN 201810207317 A CN201810207317 A CN 201810207317A CN 110279499 A CN110279499 A CN 110279499A
- Authority
- CN
- China
- Prior art keywords
- inner tube
- outer tube
- tube
- antibacterial
- silicon stent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2002/821—Ostial stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
Abstract
The present invention relates to the field of medical instrument technology, provide a kind of hydrophilic silicon stent of antibacterial, including the rack body with double layered tubular structure, outer tube that the rack body includes inner tube and is coaxially set in outside said inner tube；0.15 to 0.2 millimeter of outer path length of the internal diameter of the outer tube than inner tube；Multiple equally distributed perforative micropores are equipped on the side wall of said inner tube and outer tube, the micro-pore diameter is 0.008 to 0.01 millimeter.Silicon stent provided by the invention is while with preferable support performance, the effects of stimulation will not be generated to patient airway inside, while can also play lubrication, antiphlogistic antibacterial to air flue.
Description
Technical field
The present invention relates to the field of medical instrument technology, and in particular to a kind of hydrophilic silicon stent of antibacterial.
Background technique
When people breathes, air transtracheal and bronchus enter lung, because the lesions such as inflammatory granuloma, wound, tumour cause
Tracheae and bronchiostenosis, can cause the symptoms such as obstructive pneumonia, expiratory dyspnea, it is serious may threat to life.Tracheae
Bracket merging is one of the important means for the treatment of airway constriction, and most widely used at present is by materials systems such as Ultimum Tis
At metallic support.Compared with metal material, preparing trachea bracket using medical silicone material has many advantages, such as: due to material
It is soft, elastic good, it can accomplish lossless merging, original shape can be quickly recovered to after placement, and facilitate taking-up；Biofacies
Capacitive is good, and the stimulation generated to human body is small.
But since silicone material has adsorptivity to mucus, so that silicon stent is placed in one section of patient airway lesion locations
Mucus plugging is easy to happen after time, to influence air-flow normal through and then causing patient respiratory difficult again, so that silicone
Stented area is easy to happen a degree of infection.
Summary of the invention
The present invention provides a kind of new silicon stents, for being easy hair after solving existing silicon stent merging patient airway
Raw mucus plugging, the problem of so as to cause infection.
The purpose of the present invention is to provide a kind of hydrophilic silicon stents of antibacterial, including the bracket master with double layered tubular structure
Body, the outer tube that the rack body includes inner tube and is coaxially set in outside said inner tube；The internal diameter of the outer tube is than inner tube
Outer diameter is 0.15 to 0.2 millimeter big；Multiple equally distributed perforative micropores are equipped on the side wall of said inner tube and outer tube, it is described
The diameter of micropore is 0.008 to 0.01 millimeter.
Further, after said inner tube both ends are tightly connected with the outer tube both ends respectively, between said inner tube and outer tube
Form the load medicine cavity for storing drug.
Further, described to carry hydrophilic lubrication liquid and the antibacterials for storing that mass ratio is 100 to 300 in medicine cavity, institute
Stating hydrophilic lubrication liquid is polyethylene glycol and/or Amino End Group polyethylene glycol；The antibacterials are polyhexamethylene guanide and/or sharp good fortune
It is flat.
Further, said inner tube and outer tube are made of medical grade silicone material, and the shore hardness of the outer tube is 30
To 50HA；The shore hardness of said inner tube is 65 to 75HA.
The hydrophilic silicon stent structure of antibacterial provided by the invention is simple, by the way that double layered tubular structure is arranged, rises to air flue
While preferable supporting role, stimulation will not be generated to air flue inside；In addition, being stored using the load medicine cavity between inner and outer tubes
The effects of hydrophilic lubrication liquid and antibacterials can also play lubrication, antiphlogistic antibacterial to air flue.
Detailed description of the invention
Fig. 1 is the hydrophilic silicon stent structural schematic diagram of antibacterial in first embodiment of the invention.
Fig. 2 is the top view of the hydrophilic silicon stent of antibacterial in first embodiment of the invention.
Fig. 3 is the cross-sectional view in the face A-A in Fig. 2.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with drawings and the embodiments,
The present invention will be described in further detail.
With reference to Fig. 1, Fig. 2, first embodiment of the invention provides a kind of hydrophilic silicon stent 1 of antibacterial, including rack body
11, the rack body 11 is double layered tubular structure, the outer tube including inner tube 111 and being coaxially set in outside said inner tube 111
112；0.15 to 0.2 millimeter of outer path length of the internal diameter of the outer tube 112 than inner tube 111；The side of said inner tube 111 and outer tube 112
Multiple equally distributed perforative micropores 12 are equipped on wall, the diameter of the micropore 12 is 0.008 to 0.01 millimeter.
When operation, it can be and be directly placed in the patient the silicon stent of customized lengths, as needed will be also possible to
Longer silicon stent tube body is cut into specific length, then is placed in the patient.When the silicone for using customized lengths in operation
When bracket, said inner tube and outer tube both ends are formed between said inner tube and outer tube respectively and after the sealed connection of the outer tube both ends
For storing the load medicine cavity of drug；It, can be after cutting again by silicone when needing to cut silicon stent as needed when operation
Bracket inner tube both ends and outer tube both ends are tightly connected.
Further, described to carry hydrophilic lubrication liquid and the antibacterials for storing that mass ratio is 100 to 300 in medicine cavity, institute
State hydrophilic lubrication liquid level polyethylene glycol and/or Amino End Group polyethylene glycol；The antibacterials are polyhexamethylene guanide and/or sharp good fortune
It is flat.The hydrophilic lubrication liquid and antibacterials can be the injection before inner tube and outer tube end are tightly connected and carry medicine cavity.
The present embodiment passes through the silicon stent of setting double layered tubular structure, so as to utilize the load between inner and outer tubes
Medicine cavity stores hydrophilic lubrication liquid and antibacterials；After silicon stent is placed in patient airway lesion locations, silicon stent inner and outer pipes exist
It is squeezed in air flue, so that the hydrophilic lubrication liquid and antibacterials that carry in medicine cavity discharge constantly from micropore to outside, in silicone
Bracket can also play the therapeutic effects such as lubrication, antiphlogistic antibacterial to air flue while playing a supportive role to air flue, effectively prevent silicon
Occur to block again after the merging of ketone bracket.
Further, the silicon stent 1 further includes multiple anti-skid studs 13 being uniformly arranged on 112 outer wall of outer tube.This
The anti-skid stud of scheme can be stuck in patient airway position, be displaced or slide after avoiding silicon stent from being placed in.
Further, said inner tube and outer tube are made of medical grade silicone material, and the shore hardness of the outer tube is 30
To 50HA；The shore hardness of said inner tube is 65 to 75HA.The inner tube hardness of this programme is relatively large, can rise to air flue preferable
Supporting role, outer tube is flexible preferably, can reduce to the stimulation inside air flue.
The foregoing is merely better embodiments of the invention, are not intended to limit the invention, all of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within spirit and principle.
Claims (4)
1. a kind of hydrophilic silicon stent of antibacterial, which is characterized in that including the rack body with double layered tubular structure, the bracket
The outer tube that main body includes inner tube and is coaxially set in outside said inner tube；The internal diameter of the outer tube bigger than the outer diameter of inner tube 0.15 to
0.2 millimeter；Multiple equally distributed perforative micropores are equipped on the side wall of said inner tube and outer tube, the diameter of the micropore is
0.008 to 0.01 millimeter.
2. the hydrophilic silicon stent of antibacterial according to claim 1, which is characterized in that said inner tube both ends respectively with it is described outer
After pipe both ends are tightly connected, the load medicine cavity for storing drug is formed between said inner tube and outer tube.
3. the hydrophilic silicon stent of antibacterial according to claim 2, which is characterized in that store mass ratio in the load medicine cavity
For 100 to 300 hydrophilic lubrication liquid and antibacterials, the hydrophilic lubrication liquid is polyethylene glycol and/or Amino End Group polyethylene glycol；
The antibacterials are polyhexamethylene guanide and/or rifampin.
4. the hydrophilic silicon stent of band antibacterial according to claim 3, which is characterized in that said inner tube and outer tube are by medical
Grade silicone material is made, and the shore hardness of the outer tube is 30 to 50HA；The shore hardness of said inner tube is 65 to 75HA.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810207317.0A CN110279499A (en) | 2018-03-14 | 2018-03-14 | The hydrophilic silicon stent of antibacterial |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810207317.0A CN110279499A (en) | 2018-03-14 | 2018-03-14 | The hydrophilic silicon stent of antibacterial |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110279499A true CN110279499A (en) | 2019-09-27 |
Family
ID=68000734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810207317.0A Pending CN110279499A (en) | 2018-03-14 | 2018-03-14 | The hydrophilic silicon stent of antibacterial |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110279499A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112998906A (en) * | 2021-01-25 | 2021-06-22 | 广州睿康医疗科技有限公司 | Multilayer composite structure drug-loaded airway stent and preparation method thereof |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2093525U (en) * | 1991-02-27 | 1992-01-22 | 陈锡连 | Microporous tube carbonator |
| CN1260233A (en) * | 2000-01-31 | 2000-07-19 | 暨南大学 | Tubular catalytic membrane reactor for selective oxygenation of hydrocarbons |
| CN101045175A (en) * | 2006-03-29 | 2007-10-03 | 微创医疗器械(上海)有限公司 | Double-layered balloon catheter |
| CN101128227A (en) * | 2005-02-28 | 2008-02-20 | 庄臣及庄臣视力保护公司 | Methods for providing biomedical devices with hydrophilic antimicrobial coatings |
| CN203059985U (en) * | 2012-05-29 | 2013-07-17 | 李大可 | Absorbable cell carrier support for curing tubal infertility |
| CN203564386U (en) * | 2013-09-12 | 2014-04-30 | 徐贵丽 | Medical orifice support capable of slowly releasing medicine |
| CN204106256U (en) * | 2014-09-19 | 2015-01-21 | 上海市肺科医院 | A kind of fibrous membrane/yarn count frame of the novel nano for graft of trachea |
| CN104287869A (en) * | 2014-09-19 | 2015-01-21 | 上海市肺科医院 | Novel nanofiber membrane and yarn support for trachea transplantation and method for manufacturing novel nanofiber membrane and yarn support |
| US20160113788A1 (en) * | 2014-10-22 | 2016-04-28 | Boston Scientific Scimed, Inc. | Controlled tissue ingrowth stent covering |
| CN107115165A (en) * | 2017-05-11 | 2017-09-01 | 常州大学 | A kind of technology of preparing of reinforcement silicone airway stent |
-
2018
- 2018-03-14 CN CN201810207317.0A patent/CN110279499A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2093525U (en) * | 1991-02-27 | 1992-01-22 | 陈锡连 | Microporous tube carbonator |
| CN1260233A (en) * | 2000-01-31 | 2000-07-19 | 暨南大学 | Tubular catalytic membrane reactor for selective oxygenation of hydrocarbons |
| CN101128227A (en) * | 2005-02-28 | 2008-02-20 | 庄臣及庄臣视力保护公司 | Methods for providing biomedical devices with hydrophilic antimicrobial coatings |
| CN101045175A (en) * | 2006-03-29 | 2007-10-03 | 微创医疗器械(上海)有限公司 | Double-layered balloon catheter |
| CN203059985U (en) * | 2012-05-29 | 2013-07-17 | 李大可 | Absorbable cell carrier support for curing tubal infertility |
| CN203564386U (en) * | 2013-09-12 | 2014-04-30 | 徐贵丽 | Medical orifice support capable of slowly releasing medicine |
| CN204106256U (en) * | 2014-09-19 | 2015-01-21 | 上海市肺科医院 | A kind of fibrous membrane/yarn count frame of the novel nano for graft of trachea |
| CN104287869A (en) * | 2014-09-19 | 2015-01-21 | 上海市肺科医院 | Novel nanofiber membrane and yarn support for trachea transplantation and method for manufacturing novel nanofiber membrane and yarn support |
| US20160113788A1 (en) * | 2014-10-22 | 2016-04-28 | Boston Scientific Scimed, Inc. | Controlled tissue ingrowth stent covering |
| CN107115165A (en) * | 2017-05-11 | 2017-09-01 | 常州大学 | A kind of technology of preparing of reinforcement silicone airway stent |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112998906A (en) * | 2021-01-25 | 2021-06-22 | 广州睿康医疗科技有限公司 | Multilayer composite structure drug-loaded airway stent and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: Longgang District of Shenzhen City, Guangdong province 518116 Longgang Street Community 6 new road bridge Baolong Baolong Industrial Park building B building 1-3 floor Applicant after: Shenzhen meimeimeichuangyi Medical Technology Co., Ltd Address before: Longgang District of Shenzhen City, Guangdong province 518116 Longgang Street Community 6 new road bridge Baolong Baolong Industrial Park building B building 1-3 floor Applicant before: MEHOW INNOVATIVE Ltd. |
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| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190927 |