CN110269039B

CN110269039B - Rat caudal vertebra oscillator

Info

Publication number: CN110269039B
Application number: CN201910206662.7A
Authority: CN
Inventors: 吴敏; 周平辉; 张文; 毛颖基; 管晶晶; 钱景瑜
Original assignee: Individual
Current assignee: First Affiliated Hospital of Bengbu Medical College
Priority date: 2019-03-19
Filing date: 2019-03-19
Publication date: 2021-06-25
Anticipated expiration: 2039-03-19
Also published as: CN110269039A

Abstract

The invention discloses a caudal vertebra oscillator, which comprises a first clamp and a second clamp fixed on a caudal vertebra, and at least one oscillator driving the first clamp and/or the second clamp to reciprocate along the direction of the caudal vertebra. The caudal vertebra oscillator is used for simulating the intervertebral disc degeneration, and then applying periodic tensile and compressive mechanical stimulation in vitro so as to realize quantitative research of the periodic mechanical stimulation on the reversion of the intervertebral disc degeneration.

Description

Rat caudal vertebra oscillator

Technical Field

The invention belongs to an experimental animal long bone experimental device, in particular to a rat caudal vertebra oscillator.

Background

The animal bone growth experiment has very important significance for researching the treatment of the intervertebral disc. Currently, studies on rat caudal vertebrae generally focus on in vitro stretching or compression for degenerative or prosthetic studies. At present, there is no study in the industry to apply periodic tensile and compressive mechanical stimulation to long bones that have degenerated in animals.

Disclosure of Invention

To overcome the above problems, the present invention provides a caudal vertebra oscillator that facilitates applying periodic tensile and compressive mechanical stimuli to a degenerated long bone of an animal.

The invention provides a caudal vertebra oscillator, which comprises a first clamp and a second clamp fixed on a caudal vertebra, and at least one oscillator driving the first clamp and/or the second clamp to reciprocate along the direction of the caudal vertebra.

Preferably, the oscillator comprises a hollow cylindrical guide cylinder, at least one sliding block is arranged in the guide cylinder, the first clamp is connected to the sliding block, and the oscillator further comprises at least one driving device for driving the sliding block to reciprocate in the guide cylinder.

Preferably, a permanent magnet is arranged on the sliding block, an electromagnet is arranged in the guide cylinder, the electromagnet is electrically connected with a control board and a power supply, and the control board controls the power supply to provide forward and reverse currents for the electromagnet according to a set frequency so as to form periodic suction and repulsion on the permanent magnet.

Preferably, the electromagnet is connected with the sliding block through a spring.

Preferably, the guide cylinder is provided with a scale, and the first clamp is provided with a plurality of connecting points on the sliding block.

Preferably, a screw rod is arranged on the sliding block, two fastening nuts are connected to the screw rod in a threaded mode, a sliding groove is formed in the side wall of the guide cylinder, one end of the first clamp penetrates through the sliding groove and extends into the guide cylinder, a through hole is formed in the first clamp, the screw rod penetrates through the through hole to be connected with the first clamp, and the two fastening nuts are arranged at two ends of the through hole respectively to fix the first clamp.

Preferably, the first clamp and the second clamp are both clamps with clamping force provided by springs.

Preferably, two slide blocks are arranged in the guide cylinder, the first clamp and the second clamp are respectively connected to one slide block, and the guide cylinder further comprises two driving devices.

The caudal vertebra oscillator is used for simulating the intervertebral disc degeneration, and then applying periodic tensile and compressive mechanical stimulation in vitro so as to realize quantitative research of the periodic mechanical stimulation on the reversion of the intervertebral disc degeneration.

Drawings

FIG. 1 is a schematic perspective view of a caudal vertebra oscillator according to a preferred embodiment of the present invention;

fig. 2 is a schematic structural view of a caudal vertebra oscillator according to a preferred embodiment of the present invention.

Detailed Description

The following describes in further detail embodiments of the present invention.

As shown in fig. 1 and 2, a caudal vertebra oscillator of the present invention includes a first clamp 10 and a second clamp 12 fixed to a caudal vertebra, and an oscillator driving the first clamp 10 to reciprocate in a direction of the caudal vertebra.

In this embodiment, the oscillator includes a hollow cylindrical guide 16, a slider 18 is provided in the guide 16, the first jig 10 is connected to the slider 18, and a driving unit 14 for driving the slider 18 to reciprocate in the guide 16. The slider 18 is provided with a permanent magnet (not shown), the guide cylinder 16 is provided with an electromagnet (not shown), the electromagnet is electrically connected with a control board (not shown) and a power supply (not shown), and the control board controls the power supply to provide forward and reverse currents for the electromagnet according to a set frequency so as to form periodic attraction and repulsion on the permanent magnet, so that the permanent magnet is attracted to move leftwards or rightwards periodically to achieve the effect of simulating stretching and compression.

Further, the electromagnet is connected with the sliding block 18 through a spring 20, buffering is achieved through the spring 20, and large oscillation is converted into a plurality of small oscillations, so that the experimental effect is improved.

The guide cylinder 16 is provided with a scale and the first clamp 10 has a plurality of attachment points on the slide 18 so that the magnitude of tension and compression can be adjusted.

In this embodiment, a screw 22 is disposed on the slider 18, two fastening nuts 24 are threadedly connected to the screw 22, a sliding slot 26 is disposed on the side wall of the guide cylinder 16, one end of the first fixture 10 passes through the sliding slot 26 and extends into the guide cylinder 16, a through hole (not shown) is disposed on the first fixture 10, the screw 22 passes through the through hole to connect the first fixture 10, and the two fastening nuts 24 are disposed at two ends of the through hole respectively to fix the first fixture 10. In this way, the function of the first gripper 10 for adjusting the position on the slide 18 is achieved.

In this embodiment, the first clamp 10 and the second clamp 12 are each a clip whose clamping force is provided by a spring (not shown).

Of course, it is also possible to move the two clamps simultaneously, i.e. to provide two slides 18 in the guide 16, to which slides 18 the first clamp 10 and the second clamp 12 are respectively connected, and to include two drive devices 14 for driving the first clamp 10 and the second clamp 12.

The above structure is matched with a control unit (not shown) connected with the driving device 14, so that the adjustment of the oscillation frequency, the force and the frequency can be realized, and the quantitative research can be carried out.

Of course, the structure is not limited to the embodiment, and those skilled in the art can make many alternative solutions according to the idea of the present invention. For example: the reciprocating motion of the slide block 18 is achieved by a motor driving an eccentric cam to rotate and then connecting the slide block 18 through a link. Or a linear motor is used to drive the slider 18 to reciprocate, etc. There are many alternatives for securing the first clamp 10 to the slide 18, such as using a clip to clip onto the slide 18.

The above embodiment is only one embodiment of the present invention, and the description thereof is specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A caudal vertebra oscillator, comprising a first clamp and a second clamp secured to a caudal vertebra, characterized in that: the device also comprises at least one oscillator for driving the first clamp and/or the second clamp to reciprocate along the direction of the caudal vertebra;

the oscillator comprises a hollow cylindrical guide cylinder, at least one sliding block is arranged in the guide cylinder, the first clamp is connected to the sliding block, and the oscillator further comprises at least one driving device for driving the sliding block to reciprocate in the guide cylinder;

the sliding block is provided with a permanent magnet, the guide cylinder is internally provided with an electromagnet, the electromagnet is electrically connected with a control board and a power supply, and the control board controls the power supply to provide forward and reverse currents for the electromagnet according to a set frequency so as to form periodic suction and repulsion to the permanent magnet;

the electromagnet is connected with the sliding block through a spring.

2. The caudal vertebra oscillator of claim 1, wherein: the guide cylinder is provided with scales, and the first clamp is provided with a plurality of connecting points on the sliding block.

3. The caudal vertebra oscillator of claim 2, wherein: the slider is provided with a screw rod, the screw rod is in threaded connection with two fastening nuts, a sliding groove is formed in the side wall of the guide cylinder, one end of the first clamp penetrates through the sliding groove and extends into the guide cylinder, a through hole is formed in the first clamp, the screw rod penetrates through the through hole to be connected with the first clamp, and the two fastening nuts are respectively arranged at two ends of the through hole to fix the first clamp.

4. The caudal vertebra oscillator of claim 3, wherein: the guide cylinder is internally provided with two sliding blocks, the first clamp and the second clamp are respectively connected to one sliding block, and the guide cylinder further comprises two driving devices.

5. The caudal vertebra oscillator of claim 4, wherein: the first clamp and the second clamp are both clamps with clamping force provided by springs.