CN110250389A - A kind of the compound probiotic solid beverage and preparation method of auxiliary adjustment blood pressure and blood lipoid - Google Patents
A kind of the compound probiotic solid beverage and preparation method of auxiliary adjustment blood pressure and blood lipoid Download PDFInfo
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- CN110250389A CN110250389A CN201910641665.3A CN201910641665A CN110250389A CN 110250389 A CN110250389 A CN 110250389A CN 201910641665 A CN201910641665 A CN 201910641665A CN 110250389 A CN110250389 A CN 110250389A
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- compound probiotic
- powder
- solid beverage
- cfu
- probiotic solid
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention provides a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid and preparation methods, the compound probiotic solid beverage includes following raw material: based on mass percentage, prebiotics 20-90%, compound probiotic powder 0.1-20%, medicinal and edible plant powder 0.1-5% and fruit vegetable powder 0.1-15%.Due in medicinal and edible plant tissue fiber and polysaccharide can be used as the roles of prebiotics and utilized by probiotics, so that the effective component with blood pressure and blood lipoid regulatory function sealed up for safekeeping in plant tissue is released, therefore the present invention can further increase the regulating effect to blood pressure and blood lipoid.
Description
Technical field
The present invention relates to field of functional food, in particular to a kind of compound probiotic solid of auxiliary adjustment blood pressure and blood lipoid
Beverage and preparation method.
Background technique
Extremely as typical slow disease, drug therapy is only working blood pressure and blood lipoid in short term, and palliative, is only used for a small amount of
Critical patients, most mild or moderate blood pressure and blood lipoids are abnormal or based on the life styles adjustment such as diet movement, wherein especially
It is more crucial with diet modification.
Probiotics refers to the balance that can improve host (such as animals or humans) enteral Tiny ecosystem, and has positive benefit to host
Active microorganism, have alleviate lactase deficiency shape, prevention genital system infection, enhance human immunity, reduce serum gallbladder
Sterol, help absorb the effects of nutritional ingredient, enhancing plant metabolism.Beneficial bacterium or fungi master in human body, animal body
There are clostridium butyricum, lactic acid bacteria, Bifidobacterium, lactobacillus acidophilus, actinomyces, saccharomycete etc., is widely used in biological work
Journey, industrial or agricultural, food safety and life and health field.In April, 2010, China, which has issued, " can be used for the strain name of food
It is single ", by the part strain in three Bifidobacterium, lactobacillus and streptococcus Pseudomonas, such as bifidobacterium adolescentis, newborn bifid bar
The probiotics strain such as bacterium, Lactobacillus casei, lactobacillus plantarum, incorporates the strain range that can be used for food, and probiotics eats
It formally starts to walk in China.
Currently, probiotics is predominantly made an addition to baby milk powder, Yoghourt, drink in the application of field of food by China probiotics
In material, the market of the probiotics terminal consumer goods such as probiotic powder, bacterium piece and solid beverage is also in Fast Growth.In recent years,
Probiotic powder solid beverage market rapid development promotes intestinal health, maintains intestinal flora balance, improves the ability of immunity
Have become consumer to be known together.
It is existing more to research of the probiotics solid beverage in terms of enteron aisle adjusting and immunity adjusting, in blood pressure and blood lipoid tune
The research for saving aspect is very few.For example, currently existing scheme is mainly, screening has the bacterial strain of blood pressure and blood lipoid regulating power, then is made
It mixes as after freeze-dried powder with prebiotics, after this product mix is taken, is only played a role in enteron aisle with probiotics.
In addition, the first choice that conditioning is many people is carried out by integration of drinking and medicinal herbs product for blood glucose and dyslipidemia, while
Its effect is demonstrated in Chinese permanent traditional use, therefore integration of drinking and medicinal herbs class product is numerous in the market.
Under normal conditions, the special component in integration of drinking and medicinal herbs product can play the effect for adjusting blood glucose and blood lipid.But, medicine
Edible product is mostly directly mixed in product with plant leaf, rhizome, fruit powder, and effective component majority is mothballed in fiber, more
It in sugar and histocyte, also fails to be discharged well after taking, so that utilization rate substantially reduces, and then influences to adjust effect
Fruit.
As it can be seen that existing product is not ideal enough to the regulating effect of blood pressure and blood lipoid.
Summary of the invention
The present invention provides a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid and preparation method, Neng Goujin
One step improves the regulating effect to blood pressure and blood lipoid.
In order to achieve the above object, the present invention is achieved through the following technical solutions:
A kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, may include following raw material: by quality percentage
Content meter, prebiotics 20-90%, compound probiotic powder 0.1-20%, medicinal and edible plant powder 0.1-5% and fruit vegetable powder 0.1-
15%.Wherein, prebiotics, compound probiotic powder, medicinal and edible plant powder, fruit vegetable powder all can be this field conventional raw material.
Fruit vegetable powder can be Fruit powder and/or Vegetable powder.
This solid beverage at least can have following characteristics:
Feature 1: effective component contained in integration of drinking and medicinal herbs is preferably discharged.
Specifically, the role that the fiber in medicinal and edible plant tissue and polysaccharide can be used as prebiotics is utilized by probiotics,
It is obtained so that sealing effective component in plant tissue, with blood pressure and blood lipoid regulatory function up for safekeeping by fiber and polysaccharide in plant
Sufficiently release.
In one of the embodiments, medicinal and edible plant powder may include kudzu-vine root powder, radix polygonati officinalis powder, lily root flour, mulberry leaf powder,
At least one of yam flour.It preferably, at least may include kudzu-vine root powder.
Feature 2: it can provide nutrition supply and promote probiotics flora proliferation.
Specifically, prebiotics and fiber and polysaccharide in medicinal and edible plant tissue, can be by probiotics as food.This
Outside, protein present in medicinal and edible plant, carbohydrate, lipid, minerals etc. can be used as carbon source, nitrogen source and microelement, from
And certain nutriment is provided for the growth of probiotics.
Feature 3: mouthfeel smell is fresh and clean, without adding artificial synthetic essence fragrance.
Specifically, natural fruit vegetable powder usually has specific flavor, so that the solid added with a certain amount of fruit vegetable powder is drunk
Material has corresponding particular flavor, and pure natural fragrance taste is easier to be received by consumer, without adding traditional flavors and fragrances
To adjust flavor.
Fruit vegetable powder preferably may include pumpkin powder in one of the embodiments,.
Feature 4: it is full of nutrition and balanced, be conducive to the adjusting of blood pressure and blood lipoid.
Specifically, fruit vegetable powder is full of nutrition, and the influence to blood pressure and blood lipoid is smaller, not only can be with using fruit vegetable powder as ingredient
Intake of the body to the ingredient for being unfavorable for blood pressure and blood lipoid is weakened, while can ensure that necessary nutriment is balanced.
Specifically, the nutritional ingredients such as vitamin rich in, minerals, protein in fruit vegetable powder, it is possible to provide human body is just
Nutrition necessary to being often metabolized.It, therefore can since blood pressure and blood lipoid exception person majority can be with the shortage problem of vitamin and mineral
Reasonable supplement is carried out to be improved by fruit vegetable powder, so that mode of the fruit vegetable powder through supplementing the nutrients carrys out indirect auxiliary adjustment
Blood pressure and blood lipoid.
In this way, compound probiotic solid beverage can also include the following raw material: grain dust in one of the embodiments,
And/or dietary fiber.
About effect:
In view of adaptability of the different probiotics for environment is mostly different, therefore the accounting of integration of drinking and medicinal herbs raw material is usual
Can not be too high, when avoiding integration of drinking and medicinal herbs excessive concentration, the activity component concentration in integration of drinking and medicinal herbs is accordingly excessively high, consequently, it is possible to right
Growth of probiotics has an impact.Certainly, required blood pressure and blood lipoid regulating effect is not achieved to avoid activity component concentration too low,
Therefore this accounting be also not easy it is too low.In this way, this accounting can be 0.1-5%, specifically can with value 0.1%, 0.3%,
0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5% etc..
It is insufficient to avoid the occurrence of probiotics fermention integration of drinking and medicinal herbs so that in integration of drinking and medicinal herbs active constituent bioavilability
The case where being affected, and to improve number of live bacteria of probiotics in human body intestinal canal, the accounting of compound probiotic powder is not easy too low.Such as
This, this accounting can be 0.1-20%, specifically can with value 0.1%, 0.5%, 1%, 3%, 5%, 10%, 15%,
18%, 20% etc..
To guarantee that probiotics has enough food, so as to preferably play blood pressure and blood lipoid adjustment effect, prebiotics
Accounting is not easy too low.In this way, this accounting can be 20-90%, specifically can with value 20%, 30%, 40%, 50%,
60%, 70%, 80%, 90% etc..
About mouthfeel:
The presence of fruit vegetable powder can contribute pure natural fragrance taste and mouthfeel, therefore the accounting of fruit vegetable powder can be 0.1-15%,
It specifically can be with value 0.1%, 0.3%, 0.5%, 1%, 3%, 5%, 10%, 13%, 15% etc..
In view of integration of drinking and medicinal herbs powder usually has particular flavor, therefore it can guarantee do not have the case where substantial influence to overall taste
Under, maximum is added to as far as possible.The accounting of medicinal and edible plant powder can be 0.1-5%.
In conclusion can be for the compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, by prebiotic for this
Mutual promoting action between bacterium and medicinal and edible plant not only can preferably discharge effective contained in medicinal and edible plant
Ingredient, while the Microflora of probiotics can be improved, so that blood pressure and blood lipoid regulating effect is improved.In addition, natural fruit and vegetables
The addition of powder can substitute existing artificial synthetic essence fragrance completely, while so that solid beverage has fresh and clean mouthfeel,
Offer enrich it is balanced nutritious, be conducive to assist blood pressure and blood lipoid adjust.
For above-mentioned compound probiotic solid beverage, organic acid and acylate in medicinal and edible plant usually may be used
Play pH buffering effect, thus have around probiotics provide one it is relatively stable and be suitable for its existence growth pH environment can
It can property.In addition, the substances such as flavonoids, saponins, alkaloid and volatile oil in medicinal and edible plant, usually there is inhibition harmful bacteria
The effect of growth, thus a possibility that promising proliferation of probiotics remains more spaces and nutriment.
Compound probiotic solid beverage further includes following raw material in one of the embodiments: calcium silicates and/or malt paste
Essence；Accordingly, the mass percentage of calcium silicates is not more than 5%, and the mass percentage of maltodextrin is not more than 40%.Its
In, calcium silicates, maltodextrin all can be this field conventional raw material.
Powder is smooth in the certifiable production pouring process of calcium silicates is not adhered, in order to avoid occur may cause because carbohydrate is more
Be seriously adhered, cause production equipment can not the problems such as normal filling, product appearance and mouthfeel are bad, user experience reduces.It can
A certain amount of calcium silicates is added according to the technological requirements, and to be used for powder agglomeration resistance, good fluidity is not adhered equipment, reduces loss.
The accounting of calcium silicates can be 0-5%, for example, can for 0%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%,
4%, 4.5%, 5% etc..
Maltodextrin belongs to auxiliary material, the ratio that the mainly comprehensive optimal ratio of mouthfeel and production are easiest to.In view of benefit
Raw member mostly can be pleasantly sweet, directly oral to feel very sweet tea, and blood pressure and blood lipoid exception person generally can limit and eat sweet tea, in the sense of taste
Can be especially sensitive to sweet taste, therefore this sweetless component of a certain amount of maltodextrin can be used to reduce the sugariness of entire product.
The accounting of maltodextrin can be 0-40%, for example, can with value 0%, 5%, 10%, 15%, 20%, 25%, 30%, 35%,
40% etc..
The prebiotics include: polydextrose, oligofructose, at least one in lactitol in one of the embodiments,
Kind.Wherein, it is contemplated that oligofructose, lactitol are all pleasantly sweet, therefore can this sweetless component is entire to reduce with polydextrose
The sugariness of product.
The mass percentage of raw material in one of the embodiments, are as follows: polydextrose 5-25%, oligofructose 10-
40%, lactitol 10-40%.For example polydextrose can be 5%, 10%, 15%, 20%, 25% etc., oligofructose can be
10%, 15%, 20%, 25%, 30%, 35%, 40% etc., lactitol can for 10%, 15%, 20%, 25%, 30%,
35%, 40% etc..
Compound probiotic solid beverage includes the raw material of following mass percentage in one of the embodiments: poly- Portugal
Grape sugar 12-18%, oligofructose 15-20%, lactitol 22-28%, compound probiotic powder 8-12%, kudzu-vine root powder 0.1-3%, hair
Ferment pumpkin powder 3-8%, calcium silicates 0-3%, maltodextrin 22-28%.
For example, polydextrose can be 12%, 13%, 14%, 15%, 16%, 17%, 18% etc.；Oligofructose can be with
It is 15%, 16%, 17%, 18%, 19%, 20% etc.；Lactitol can for 22%, 23%, 24%, 25%, 26%, 27%,
28% etc.；Compound probiotic powder can be 8%, 9%, 10%, 11%, 12% etc.；Kudzu-vine root powder can for 0.1%, 0.3%,
0.5%, 1%, 1.5%, 2%, 2.5%, 3% etc.；The pumpkin powder that ferments can be 3%, 4%, 5%, 6%, 7%, 8% etc.；Silicon
Sour calcium can be 0%, 0.1%, 0.3%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3% etc.；Maltodextrin can for 22%,
23%, 24%, 25%, 26%, 27%, 28% etc..
In the embodiment of the present invention, pre-fermented pumpkin powder is can be selected in fruit vegetable powder.For example, can be take fresh pumpkin as original
Material after addition probiotics is fermented, then is concentrated by ultrafiltration and manufactured fermentation pumpkin powder after freeze drying process processing.This hair
In bright embodiment, kudzu-vine root powder is can be selected in medicinal and edible plant powder, it might even be possible to be pre-fermented kudzu-vine root powder.Specifically, fermentation is used
The bacterial strain of probiotics can select one or more existing bacterial strains on demand.
The medicinal and edible plant powder is pre-fermented medicinal and edible plant powder in one of the embodiments,.Due to pre-
Medicinal and edible plant powder after fermentation no longer needs to ferment, and can directly be absorbed, and so there is no need to use probiotics and solid in enteron aisle
Probiotics in beverage, so that can have more probiotics for adjusting blood pressure and blood lipoid in enteron aisle.
The fruit vegetable powder is pre-fermented fruit vegetable powder in one of the embodiments,.Probiotics fermention fruit vegetable powder, further
Nutritive value, enhancing auxiliary blood pressure and blood lipoid immunoregulation function are promoted, while mouthfeel is strong fragrant fresh and sweet.
Specifically, when probiotics fermention fruits and vegetables, it is non-but not make fruits and vegetables idiotrophic ingredient degradation lose, instead favorably
Nutritive value in promotion fruits and vegetables.In the metabolic process, the soluble substance in probiotics metabolism raw material, can drop partial fat
Solution becomes the beneficial short chain fatty acids of human body.Other part vitamin can be consumed by probiotics, regenerate the dimension life of the B such as folic acid race
Element.The organic acid that probiotics generates in the metabolic process can not only reduce system pH, enhance the stability of B family vitamin, and
And the cycling of elements ionic state such as make calcium and phosphorus, it is easier to which be absorbed by the body utilization.
In the following, introducing some existing clinical laboratory datas:
(1)
Bacterial strain: NCFM takes metering: 10,000,000,000 CFU/ days, the test period: 4 weeks；
Test population: type 2 diabetic patient 24, non-diabetic patients 24, randomized double-blind is distributed in probiotic group 24
Example and placebo 24；
Experiment conclusion: comparison placebo keeps preferable using the insulin sensitivity of probiotic group；
Original text document: British Journal of Nutrition (2010), 104,1831-1838.
(2)
Bacterial strain: HN001 takes metering: 6,000,000,000 CFU/ days, the test period: 10-15 weeks；
Test population: the pregnant woman of total 423 different pregnancy phases, random selection use probiotics 212, and selection is using comfort
Agent 211；
Experiment conclusion: comparison placebo, probiotics intervention group gestational diabetes mellitus disease incidence are lower；
Original text document: British Journal of Nutrition (2017), 117,804-813.
(3)
Bacterial strain: GG takes metering: 1,000,000,000 CFU/ days, the test period: 7-8 weeks；
Test population: 35 average 5.5 months monthly ages suffer from or the doubtful children with atopic dermatitis；
Experiment conclusion: GG probiotic group SCORAD scoring is significant to lower, and illustrates that probiotics is intervened and significantly reduces idiocrasy
The adverse reaction of dermatitis；
Original text document: J.Pediatr.Gastr.Nutr.2003,36,223-227.
(4)
Bacterial strain: HN019 takes metering: 27,200,000,000 CFU/ days, the test period: 45 days；
Test population: amount to 51 metabolic syndrome patients, be divided into 25 people of control group, 26 people of probiotic group；
Experiment conclusion: it periodically takes probiotics and advantageously reduces Metabolic syndrome and seek peace fat performance parameter；
Original text document: Nutrition 32 (2016) 716-719.
(5)
Bacterial strain: B-420 takes metering: 10,000,000,000 CFU/ days, the test period: 6 months；
Test population: 225 healthy volunteers are randomly divided into 4 groups；
Experiment conclusion: probiotics and dietary fiber or probiotics individually reduce the intake of energy and reduce total body fat
Amount；
Original text document: EBioMedicine 13 (2016) 190-200.
In detail, blood glucose and Dyslipidemia can cause metabolic syndrome, and human body is caused Obese Characteristics occur；Blood lipid is high
It will lead to body fat height；When hypoimmunity, atopic dermatitis can be caused, the problems such as blood pressure and blood lipoid is abnormal.
Based on this, the compound probiotic powder includes: lactobacillus acidophilus NCFM, rhamnose in one of the embodiments,
Lactobacillus HN001, Lactobacillus rhamnosus GG, bifidobacterium lactis HN-019, at least two in bifidobacterium lactis B-420.
Specifically, the probiotics strain for having clear effect is adjusted to blood pressure and blood lipoid according to what is filtered out in advance, carried out
Reasonable combination, available one group has the compound probiotic of definite effect to combine.It specifically, can be according to clinical trial to prove benefit
Bacteria strain is given birth to the immunoregulation function of blood pressure and blood lipoid, and is suitably increased according to the preferable additive amount of clinical trial effect.
Based on this, in one of the embodiments, in the compound probiotic solid beverage each probiotics total content
Are as follows: lactobacillus acidophilus NCFM:1.0-3.0 × 1010CFU；Lactobacillus rhamnosus HN001:2.0-10.0 × 109CFU；Rhamnose cream
Bacillus GG:2.0-10.0 × 109CFU；Bifidobacterium lactis HN-019:1.0-5.0 × 109CFU；Bifidobacterium lactis B-420:1.0-
5.0×109CFU。
For example, for this value interval of 1.0-3.0, specific value can for 1.0,1.2,1.5,2.0,2.5 or
3.0；For this value interval of 2.0-10.0, specific value can for 2.0,3.0,4.0,5.0,6.0,7.0,8.0,9.0 or
10.0；For this value interval of 1.0-5.0, specific value can be 1.0,2.0,3.0,4.0 or 5.0.
Any of the above-described compound probiotic solid beverage in one of the embodiments, can be applied to preparation and be used for
Adjust the functional food or health food of blood pressure and blood lipoid.
In addition, the present invention also provides a kind of preparation method for preparing any of the above-described compound probiotic solid beverage,
It may comprise steps of:
Step 1: it will be used to prepare each raw material stoving of compound probiotic solid beverage, and cross 40 meshes；
Step 2: each raw material after sieving is uniformly mixed in blender；
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer；
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Specifically, drying processing and sieving processing, it is ensured that good moisture content and granularity.It is dry through above-mentioned raw materials
The solid beverage product that mixed preparation process prepares, have stay in grade, viable count height, long shelf-life, storing require it is low, be not necessarily to
The features such as refrigerated storage, product market prospects are good.
In conclusion compared with prior art, the present invention can further increase the regulating effect to blood pressure and blood lipoid.
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described, it is clear that described embodiments are some of the embodiments of the present invention, rather than
Whole embodiments, based on the embodiments of the present invention, those of ordinary skill in the art are not before making creative work
Every other embodiment obtained is put, shall fall within the protection scope of the present invention.
It should be noted that experimental method described in following embodiments is unless otherwise specified conventional method, institute
Reagent and material are stated, unless otherwise specified, is commercially obtained.
One, preparation example
Embodiment 1
The mass percentage of a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, raw material composition is as follows
It states shown in table 1:
Table 1
| Raw material | Number | Raw material | Number |
| Polydextrose | 15 | Kudzu-vine root powder | 0.1 |
| Oligofructose | 18 | Ferment pumpkin powder | 6 |
| Lactitol | 25 | Calcium silicates | 1 |
| Compound probiotic powder | 9.9 | Maltodextrin | 25 |
Wherein, compound probiotic powder includes: lactobacillus acidophilus NCFM:1.5 × 1010CFU；Lactobacillus rhamnosus HN001:
5.0×109CFU；Lactobacillus rhamnosus GG:5.0 × 109CFU；Bifidobacterium lactis HN-019:3.0 × 109CFU；Bifidobacterium lactis
B-420:2.0 × 109CFU。
Preparation method is as follows:
Step 1: by 15 parts of polydextrose, 18 parts of oligofructose, 25 parts of lactitol, 9.9 parts of compound probiotic powder, pueraria lobata
0.1 part of powder, fermentation 6 parts of pumpkin powder, 25 parts of 1 part of calcium silicates, maltodextrin these raw material stovings, and cross 40 meshes.
Step 2: each raw material after sieving is uniformly mixed in blender.
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer.
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Embodiment 2
The mass percentage of a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, raw material composition is as follows
It states shown in table 2:
Table 2
| Raw material | Number | Raw material | Number |
| Polydextrose | 15 | Kudzu-vine root powder | 1 |
| Oligofructose | 18 | Ferment pumpkin powder | 8 |
| Lactitol | 25 | Calcium silicates | 1 |
| Compound probiotic powder | 9.9 | Maltodextrin | 22.1 |
Wherein, compound probiotic powder includes: lactobacillus acidophilus NCFM:1.5 × 1010CFU；Lactobacillus rhamnosus HN001:
5.0×109CFU；Lactobacillus rhamnosus GG:5.0 × 109CFU；Bifidobacterium lactis HN-019:3.0 × 109CFU；Bifidobacterium lactis
B-420:2.0 × 109CFU。
Preparation method is as follows:
Step 1: by 15 parts of polydextrose, 18 parts of oligofructose, 25 parts of lactitol, 9.9 parts of compound probiotic powder, pueraria lobata
1 part of powder, fermentation 8 parts of pumpkin powder, 22.1 parts of 1 part of calcium silicates, maltodextrin these raw material stovings, and cross 40 meshes.
Step 2: each raw material after sieving is uniformly mixed in blender.
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer.
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Embodiment 3
The mass percentage of a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, raw material composition is as follows
It states shown in table 3:
Table 3
| Raw material | Number | Raw material | Number |
| Polydextrose | 15 | Kudzu-vine root powder | 5 |
| Oligofructose | 18 | Ferment pumpkin powder | 10 |
| Lactitol | 25 | Calcium silicates | 1 |
| Compound probiotic powder | 9.9 | Maltodextrin | 16.1 |
Wherein, compound probiotic powder includes: lactobacillus acidophilus NCFM:1.5 × 1010CFU；Lactobacillus rhamnosus HN001:
5.0×109CFU；Lactobacillus rhamnosus GG:5.0 × 109CFU；Bifidobacterium lactis HN-019:3.0 × 109CFU；Bifidobacterium lactis
B-420:2.0 × 109CFU。
Preparation method is as follows:
Step 1: by 15 parts of polydextrose, 18 parts of oligofructose, 25 parts of lactitol, 9.9 parts of compound probiotic powder, pueraria lobata
5 parts of powder, fermentation 10 parts of pumpkin powder, 16.1 parts of 1 part of calcium silicates, maltodextrin these raw material stovings, and cross 40 meshes.
Step 2: each raw material after sieving is uniformly mixed in blender.
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer.
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Embodiment 4
The mass percentage of a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, raw material composition is as follows
It states shown in table 4:
Table 4
| Raw material | Number | Raw material | Number |
| Polydextrose | 15 | Kudzu-vine root powder | 0.1 |
| Oligofructose | 18 | Ferment pumpkin powder | 6 |
| Lactitol | 25 | Calcium silicates | 1 |
| Compound probiotic powder | 16.5 | Maltodextrin | 18.4 |
Wherein, compound probiotic powder includes: lactobacillus acidophilus NCFM:2.5 × 1010CFU；Lactobacillus rhamnosus HN001:
8.3×109CFU；Lactobacillus rhamnosus GG:8.3 × 109CFU；Bifidobacterium lactis HN-019:5.0 × 109CFU；Bifidobacterium lactis
B-420:3.3 × 109CFU。
Preparation method is as follows:
Step 1: by 15 parts of polydextrose, 18 parts of oligofructose, 25 parts of lactitol, 16.5 parts of compound probiotic powder, pueraria lobata
0.1 part of powder, fermentation 6 parts of pumpkin powder, 18.4 parts of 1 part of calcium silicates, maltodextrin these raw material stovings, and cross 40 meshes.
Step 2: each raw material after sieving is uniformly mixed in blender.
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer.
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Embodiment 5
The mass percentage of a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, raw material composition is as follows
It states shown in table 5:
Table 5
| Raw material | Number | Raw material | Number |
| Polydextrose | 15 | Rhizoma polygonati powder | 0.5 |
| Oligofructose | 18 | Ferment carrot powder | 7 |
| Lactitol | 25 | Calcium silicates | 1 |
| Compound probiotic powder | 16.5 | Maltodextrin | 17 |
Wherein, compound probiotic powder includes: lactobacillus acidophilus NCFM:1.5 × 1010CFU；Lactobacillus rhamnosus HN001:
5.0×109CFU；Lactobacillus rhamnosus GG:5.0 × 109CFU；Bifidobacterium lactis HN-019:3.0 × 109CFU；Bifidobacterium lactis
B-420:2.0 × 109CFU。
Preparation method is as follows:
Step 1: by 15 parts of polydextrose, 18 parts of oligofructose, 25 parts of lactitol, 16.5 parts of compound probiotic powder, rhizoma polygonati
17 parts of 0.5 part of powder, 7 parts of ferment carrot powder, 1 part of calcium silicates, maltodextrin these raw material stovings, and cross 40 meshes.
Step 2: each raw material after sieving is uniformly mixed in blender.
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer.
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Embodiment 6
The mass percentage of a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, raw material composition is as follows
It states shown in table 6:
Table 6
| Raw material | Number | Raw material | Number |
| Polydextrose | 15 | Kudzu-vine root powder | 0.1 |
| Oligofructose | 18 | Ferment pumpkin powder | 6 |
| Lactitol | 25 | Calcium silicates | 1 |
| Compound probiotic powder | 10 | Maltodextrin | 24.9 |
Wherein, compound probiotic powder includes: lactobacillus acidophilus NCFM:1.0 × 1010CFU；Lactobacillus rhamnosus HN001:
5.0×109CFU；Lactobacillus rhamnosus GG:5.0 × 109CFU；Bifidobacterium lactis HN-019:5.0 × 109CFU；Bifidobacterium lactis
B-420:5.0 × 109CFU。
Preparation method is as follows:
Step 1: by 15 parts of polydextrose, 18 parts of oligofructose, 25 parts of lactitol, 10 parts of compound probiotic powder, kudzu-vine root powder
0.1 part, fermentation 6 parts of pumpkin powder, 24.9 parts of 1 part of calcium silicates, maltodextrin these raw material stovings, and cross 40 meshes.
Step 2: each raw material after sieving is uniformly mixed in blender.
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer.
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs close
Lattice.
Above embodiments 1-6 is while auxiliary using prebiotics, compound probiotic, medicinal and edible plant powder, fruit vegetable powder as major ingredient
With calcium silicates and maltodextrin, by adjusting the component accounting of different material, adjusting different strains viable count in compound probiotic,
And the type of medicinal and edible plant powder and the type of fruit vegetable powder are adjusted, to obtain different blood pressure and blood lipoid immunoregulation functions, difference
Flavor, different sugariness, different mouthfeels, different colours, the compound probiotic solid beverage that meets various people, but these solids
Beverage all has the effect of auxiliary adjustment blood pressure and blood lipoid.
One, test example
Embodiment 7
7.1, supplementary material: pure water, carrot meal, kudzu-vine root powder, compound probiotic freeze-dried powder, sodium hydroxide, potassium dihydrogen phosphate,
Citric acid.
7.2, experimental design:
(1) experimental group
1. blank group: except without in addition to kudzu-vine root powder, containing other all supplementary materials shown in 7.1, and main supplementary material adds
Dosage is as described in Table 7.
2. test group: all supplementary materials shown in containing 7.1, and the additive amount of main supplementary material is as described in Table 7.
Table 7
| Main component | Blank group | Test group |
| Pure water | 400ml | 400ml |
| Compound probiotic freeze-dried powder | 4.0×1010CFU | 4.0×1010CFU |
| Carrot meal | 20g | 20g |
| Kudzu-vine root powder | 10g | 0g |
Compound probiotic freeze-dried powder in table 7 specifically includes lactobacillus acidophilus (NCFM) 2.0 × 1010CFU, rhamnose cream
Bacillus (HN001) 6.7 × 109CFU, Lactobacillus rhamnosus (GG) 6.7 × 109CFU, bifidobacterium lactis (HN-019) 4.0 ×
109CFU, bifidobacterium lactis (B-420) 2.6 × 109CFU。
(2) experiment flow
Step 1: pure water, carrot meal, kudzu-vine root powder are fitted into according to a certain percentage in 500ml vial.
Step 2: solution is adjusted to the buffer system that pH value is 6.8 with sodium hydroxide, potassium dihydrogen phosphate and citric acid,
It adjusts that temperature is constant stirs evenly at 37 DEG C, stablizes certain time.
Step 3: compound probiotic freeze-dried powder being added in vial by a certain percentage, ferment at constant temperature for 24 hours, takes quantitative later
Fermentation liquid carry out Puerarin HPLC content and total plate count detection.
Wherein, certain time can be stablized in step 2, so that the Puerarin in kudzu-vine root powder dissolves out naturally, reach balance and stability
State.
(3) experimental result
Table 8
(4) test result analysis
Compared with before fermentation, after fermentation, Puerarin dissolution increases 48.39% to test group, and probiotics Microflora has
Increased, and total plate count increases 10.64% than blank group.The results show that the presence of kudzu-vine root powder is for probiotics flora number
Amount, which increases, facilitation, and the activity of probiotics and proliferation are obviously promoted effect to the release and dissolution of Puerarin.
Embodiment 8
8.1, supplementary material: with 7.1.
8.2, experimental design:
(1) experimental group
1. blank group: except without in addition to kudzu-vine root powder, containing other all supplementary materials shown in 8.1, and main supplementary material adds
Dosage is as described in Table 9.
2. test group: all supplementary materials shown in containing 8.1, and the additive amount of main supplementary material is as described in Table 9.
Table 9
| Main component | Blank group | Test group |
| Pure water | 400ml | 400ml |
| Compound probiotic freeze-dried powder | 4.0×1010CFU | 4.0×1010CFU |
| Carrot meal | 20g | 20g |
| Kudzu-vine root powder | 20g | 0g |
The concrete composition of compound probiotic freeze-dried powder in table 9, with table 7.
(2) experiment flow
With above-mentioned steps 1-3.
(3) experimental result
Table 10
(4) test result analysis
Compared with before fermentation, after fermentation, Puerarin dissolution increases 61.82% to test group, and probiotics Microflora has
Increased, and total plate count increases 29.79% than blank group.The results show that the presence of kudzu-vine root powder is for probiotics flora number
Amount increases the effect that is obviously promoted, and the activity of probiotics and proliferation are obviously promoted effect to the release and dissolution of Puerarin.
Embodiment 9
9.1, supplementary material: with 7.1.
9.2, experimental design:
(1) experimental group
1. blank group: except without in addition to kudzu-vine root powder, containing other all supplementary materials shown in 9.1, and main supplementary material adds
Dosage is as shown in following tables 11.
2. test group: all supplementary materials shown in containing 9.1, and the additive amount of main supplementary material is as shown in following tables 11.
Table 11
| Main component | Blank group | Test group |
| Pure water | 400ml | 400ml |
| Compound probiotic freeze-dried powder | 4.0×1010CFU | 4.0×1010CFU |
| Carrot meal | 20g | 20g |
| Kudzu-vine root powder | 40g | 0g |
The concrete composition of compound probiotic freeze-dried powder in table 11, with table 7.
(2) experiment flow
With above-mentioned steps 1-3.
(3) experimental result
Table 12
(4) test result analysis
Compared with before fermentation, after fermentation, Puerarin dissolution increases 82.61% to test group, and probiotics Microflora has
Increased, and total plate count increases 44.68% than blank group.The results show that the presence of kudzu-vine root powder is for probiotics flora number
Amount increases the effect that remarkably promotes, and the activity of probiotics and proliferation remarkably promote effect to the release and dissolution of Puerarin.
Three, zoopery
Embodiment 10
10.1, experimental animal and grouping
Wister rat is 46 total, and half male and half female is randomly divided into 4 groups:
1. blank control group: 10, persistently giving normal diet until experiment terminates；
2. model control group: 12, giving high lipid food early period, give normal diet after modeling success；
3. intervention group one: 12, giving high lipid food early period, compound probiotic solid beverage+general is given after modeling success
Logical feed；
4. intervention group two: 12, giving high lipid food early period, giving compound probiotic solid beverage+height after modeling success
Rouge feed.
10.2, experimental material and method
(1) main experimental materials: normal diet, high lipid food, the compound probiotic solid prepared in above-described embodiment 1
Beverage (1.0 × 109CFU/ days/only), heparin tube, absolute alcohol, dimethylbenzene, embedding paraffin, OCT frozen tissue embedding medium, and
Other routine experiment consumptive materials.
(2) prepared by model: high lipid food is fed modeling 8 weeks.
(3) Testing index: at modeling 8 weeks, randomly selecting 4 animals from whole modeling samples, inspection model whether at
Function.Compound probiotic solid beverage intervention (1.0 × 10 is given after verifying modeling success9CFU/ days/only, continue 2 months altogether),
Eyeball is taken a blood sample when intervening 1 the end of month, detects blood biochemistry index.All animals are put to death at the end of intervention, detect blood biochemistry index.
10.3, experimental result
(1) influence (mean+SD, unit mmol/ of the compound probiotic solid beverage intervention to mouse blood sugar
L), table 13 is seen below.
Table 13
| Detection project | Blank control group | Model control group | Intervention group one | Intervention group two |
| Blood glucose before intervening | 5.31±0.58 | 11.46±1.84 | 11.21±2.13 | 11.73±2.06 |
| Intervene 30 days blood glucose | 5.78±0.49 | 11.97±2.08 | 10.01±1.22** | 10.55±1.34* |
| Intervene 60 days blood glucose | 5.56±0.67 | 11.38±1.79 | 7.83±1.52** | 8.98±1.13* |
Note: each intervention group is compared with model control group, * (P < 0.05)；**(P≤0.01).
(2) influence (mean+SD, list of the compound probiotic solid beverage intervention to blood lipid level in mice serum
Position is mmol/L), see below table 14.
Table 14
Note: each intervention group is compared with model control group, * (P < 0.05)；**(P≤0.01)；TC refers to total cholesterol；TG refers to
Total triglycerides；LDL-C index and low density lipoprotein cholesterol；HDL-C refers to high-density lipoprotein cholesterol.
10.4, analysis of experimental results
(1) it is directed to the influence of blood glucose
Compound probiotic solid beverage+normal diet is persistently given after one modeling of intervention group success, with model control group phase
Than intervention group mouse blood sugar level after probiotics is intervened is gradually reduced, and entire lowering is obvious；Two modeling of intervention group success
Compound probiotic solid beverage+high lipid food is persistently given afterwards, and compared with model control group, intervention group two is after probiotics is intervened
Mouse blood sugar level is equally gradually reduced, and is declined more obvious.
(2) it is directed to the influence of blood lipid
Compared with model control group, after probiotics is intervened, mouse TC level is gradually reduced intervention group, and is declined bright
It is aobvious；Compared with model control group, after probiotics is intervened, mouse TC level is equally declined intervention group two.
Compared with model control group, intervention group once probiotics intervene after, mouse TG level is gradually reduced, and decline compared with
It is obvious；Compared with model control group, after probiotics is intervened, mouse TG is horizontal equally to be had more significantly intervention group two
Decline.
Compared with model control group, intervention group after probiotics is intervened, mouse LDL-C level have it is more apparent under
Drop；Compared with model control group, after probiotics is intervened, the horizontal first half term variation of mouse LDL-C is not obvious intervention group two,
Intervening the second half has relatively apparent decline.
Compared with model control group, for intervention group after probiotics is intervened, ascendant trend is presented in mouse HDL-C level；
Compared with model control group, after probiotics is intervened, mouse HDL-C level slightly rises intervention group two.
(3) comprehensive analysis
On the whole, intervention group blood glucose level and blood lipid the indices oriented proper transition after probiotics is intervened
Trend, wherein persistently under the bad condition of high fat diet change degree it is on the weak side, and under the conditions of normal diet change degree it is stronger.
Illustrate that compound probiotic solid beverage product can play better blood glucose and regulating plasma lipid under conditions of keeping on a diet health
Effect, and poor eating habits and under the conditions of then fight fall a part of regulating power.
To sum up, the compound probiotic solid beverage in the embodiment of the present invention has the function of auxiliary adjustment blood pressure and blood lipoid.
It should be noted that, in this document, the terms "include", "comprise" or its any other variant are intended to non-row
His property includes, so that the process, method, article or equipment for including a series of elements not only includes those elements, and
And further include other elements that are not explicitly listed, or further include for this process, method, article or equipment institute it is intrinsic
Element.In the absence of more restrictions, the element limited by sentence " including a 〃 〃 ", it is not excluded that
There is also other identical factors in process, method, article or equipment including the element.
Finally, it should be noted that the foregoing is merely presently preferred embodiments of the present invention, it is merely to illustrate skill of the invention
Art scheme, is not intended to limit the scope of the present invention.Any modification for being made all within the spirits and principles of the present invention,
Equivalent replacement, improvement etc., are included within the scope of protection of the present invention.
Claims (10)
1. a kind of compound probiotic solid beverage of auxiliary adjustment blood pressure and blood lipoid, which is characterized in that including following raw material:
Based on mass percentage, prebiotics 20-90%, compound probiotic powder 0.1-20%, medicinal and edible plant powder 0.1-5%
With fruit vegetable powder 0.1-15%.
2. compound probiotic solid beverage according to claim 1, which is characterized in that
The compound probiotic solid beverage further includes following raw material: calcium silicates and/or maltodextrin；
Accordingly, the mass percentage of calcium silicates is not more than 5%, and the mass percentage of maltodextrin is not more than 40%.
3. compound probiotic solid beverage according to claim 1 or 2, which is characterized in that the prebiotics include: poly- Portugal
At least one of grape sugar, oligofructose, lactitol.
4. compound probiotic solid beverage according to claim 3, which is characterized in that the mass percentage of raw material are as follows:
Polydextrose 5-25%, oligofructose 10-40%, lactitol 10-40%.
5. compound probiotic solid beverage according to claim 4, which is characterized in that including following mass percentage
Raw material: polydextrose 12-18%, oligofructose 15-20%, lactitol 22-28%, compound probiotic powder 8-12%, kudzu-vine root powder
0.1-3%, fermentation pumpkin powder 3-8%, calcium silicates 0-3%, maltodextrin 22-28%.
6. compound probiotic solid beverage according to claim 1, which is characterized in that the compound probiotic powder includes:
Lactobacillus acidophilus NCFM, Lactobacillus rhamnosus HN001, Lactobacillus rhamnosus GG, bifidobacterium lactis HN-019, bifidobacterium lactis B-
At least two in 420.
7. compound probiotic solid beverage according to claim 6, which is characterized in that the compound probiotic solid beverage
In each probiotics total content are as follows:
Lactobacillus acidophilus NCFM:1.0-3.0 × 1010CFU；
Lactobacillus rhamnosus HN001:2.0-10.0 × 109CFU；
Lactobacillus rhamnosus GG:2.0-10.0 × 109CFU；
Bifidobacterium lactis HN-019:1.0-5.0 × 109CFU；
Bifidobacterium lactis B-420:1.0-5.0 × 109CFU。
8. according to claim 1 to any compound probiotic solid beverage in 7, which is characterized in that
The fruit vegetable powder is pre-fermented fruit vegetable powder；
And/or
The medicinal and edible plant powder is pre-fermented medicinal and edible plant powder.
9. the compound probiotic solid beverage as described in any in claim 1 to 8 is preparing the function for adjusting blood pressure and blood lipoid
Application in property food or health food.
10. a kind of preparation method for preparing the compound probiotic solid beverage as described in any in claim 1 to 8, feature exist
In, comprising the following steps:
Step 1: it will be used to prepare each raw material stoving of compound probiotic solid beverage, and cross 40 meshes；
Step 2: each raw material after sieving is uniformly mixed in blender；
Step 3: aseptically, uniformly mixed material combination is subjected to filling package with bottle placer；
Step 4: sampling Detection guarantees filling band viable count >=3.0 × 10 of institute10CFU, and other physical indexs are qualified.
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