CN1102404C - Superfined American ginseng capsule and preparation thereof - Google Patents

Superfined American ginseng capsule and preparation thereof Download PDF

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Publication number
CN1102404C
CN1102404C CN 97125218 CN97125218A CN1102404C CN 1102404 C CN1102404 C CN 1102404C CN 97125218 CN97125218 CN 97125218 CN 97125218 A CN97125218 A CN 97125218A CN 1102404 C CN1102404 C CN 1102404C
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China
Prior art keywords
american ginseng
capsule
glue shell
powder
superfined
Prior art date
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Expired - Lifetime
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CN 97125218
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Chinese (zh)
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CN1185968A (en
Inventor
范小兵
沙大年
徐明强
李慈娟
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ONLY CO Ltd SHANGHAI JIANTONG UNIV
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ONLY CO Ltd SHANGHAI JIANTONG UNIV
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Priority to CN 97125218 priority Critical patent/CN1102404C/en
Publication of CN1185968A publication Critical patent/CN1185968A/en
Application granted granted Critical
Publication of CN1102404C publication Critical patent/CN1102404C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention relates to an American ginseng superfine powder capsule and a preparation method thereof. The capsule comprises a capsule shell and a capsule core object, wherein the capsule shell comprises gelatin, glycerin, agar, edible pigment and hydroxy benzene ethyl formate and also comprises a biological catalyst; the capsule core object is about 500 meshes of American ginseng superfine powder with the water content of less than 4%. The American ginseng superfine powder is dried by a drying agent P2O5 by a closed drying method, the obtained powder is not agglomerated and is loose, and the original color, the original perfume and the original flavor of the American ginseng superfine powder are kept. The animal experiment proves that the absorptivity of the capsule is enhanced from 6% to 10%. The capsule is ideal Chinese patent medicine of American ginseng superfine powder.

Description

Superfined American ginseng capsule and preparation method thereof
The present invention is a kind of superfined American ginseng capsule and preparation method thereof.American ginseng capsule is a kind of Chinese patent medicine to specific medical treatment of human body and tonic effect.
Prior art
(1) application for a patent for invention (CN1139556A, A61K 35/78 A61J 3/02) discloses a kind of " ultramicro active ginseng powder and technology of preparing thereof " its inventor Zhang Jianqiu in and proposed to utilize jet mill to be capital equipment, various Radix Ginsengs pulverizing have been the ultramicro active ginseng powder of particle mean size less than 5 microns.
(2) author Cao Zhaobo and Zhang Shuxian " use the constant temperature hypobaric drying method and measure Chinese patent medicine moisture " 14 the 7th phases of volume of " Chinese herbal medicine " nineteen eighty-three of delivering, the 42nd page), proposition has concentrated sulphuric acid, silica gel, calcium fluoride, phosphorus pentoxide with desiccant, best with the phosphorus pentoxide effect, decompression freeze-day with constant temperature method is measured the moisture in the Chinese patent medicine.
(3) American ginseng capsule, as ten thousand basic Radix Panacis Quinquefoliis (manufacturing of Shenzhen Wan Ji pharmaceutical Co. Ltd), gold day board U.S.'s Radix Panacis Quinquefolii (Mei Hua pharmaceutical factory), a continent American ginseng pill (restriction Co., Ltd., Factory in a continent produces) etc., it consists of glue shell and capsule core material two parts.
Glue shell: contain gelatin, glycerol, agar, food coloring, ethylparaben.
Capsule core material: the American Ginseng powder about 80 orders.The Radix Panacis Quinquefolii composition contains total panaquilon, volatile oil, starch, protein, organic acid.
Capsule core material drying mode: pneumatic conveying drying or vacuum drying.
Above-mentioned prior art (1) is only pulverized various Radix Ginsengs, and that make at last is the Radix Ginseng powder,, the experiment proved that granularity is too little may not be favourable though granularity is absorbed by the body easily less than 5 microns the Radix Ginseng powder Radix Ginseng powder bigger than granularity.And take from being convenient for people to, more perfectly keep the color of Radix Panacis Quinquefolii itself enduringly and aspect such as be absorbed by the body more fully, also very undesirable.
Above-mentioned prior art (2) is a kind of method that is adopted when Chinese patent medicine is measured contained humidity, Chinese patent medicine itself is not handled, and the method that is adopted simultaneously is a decompression freeze-day with constant temperature method, promptly is the vacuum constant temperature seasoning.
Dimeric American ginseng capsule in the above-mentioned prior art (3) be difficult to guarantee the original color of Radix Panacis Quinquefolii and is absorbed fully fast by human body.
The objective of the invention is to prepare a kind of new American ginseng capsule, can remedy the deficiency of existing procucts, can guarantee that the original color of Radix Panacis Quinquefolii is not wandered away in the product, make dry thing more loose, be convenient to packing.Can make the utilization that is absorbed by the body fully fast of the effective ingredient of its health care again, improve health care usefulness.
American ginseng capsule of the present invention has bigger difference concrete the composition with existing products.Capsule of the present invention is made up of glue shell and capsule core material: the glue shell: contain gelatin, glycerol, agar, food coloring, ethylparaben and biocatalyzer.Wherein biocatalyzer such as α-Dian Fenmei, beta amylase, isoamylase, pectase, saccharifying enzyme etc.Adding biocatalyzer kind and consumption decides according to capsule core material composition and content thereof.As capsule core material is Radix Panacis Quinquefolii, and 30% starch is optional according to appointment adds alphalise starch acid according to the content of Radix Panacis Quinquefolii composition, and consumption is 71.7 (μ l/g) of glue shell.Impel in its reducing sugar experimental result susceptible of proof according to surveying and determination, glue shell that macromolecular starch can be transformed into micromolecular monosaccharide in the Radix Panacis Quinquefolii after enzyme-added, and not enzyme-added in the glue shell, the macromolecules starch difficulty is transformed into micromolecular monosaccharide.As shown in table 1.
After adding enzyme in the table 1 glue shell, the content of reducing sugar in the capsule
Capsule core material: the superfined American ginseng about 500 orders.Animal test results: the absorbance of 80 order left and right sides American Ginseng powders is that the absorbance of 6%, 500 order left and right sides American Ginseng powder is 10%.
Capsule core material drying mode: P 2O 5Close drying adopts this drying mode, can guarantee that the original color of Radix Panacis Quinquefolii do not wander away, and dried powder do not lump, and is more loose, is applicable to contain the volatile ingredient drying of the medicinal herb components of non-refractory again.
Preparation method: prepare the glue shell earlier, again the American Ginseng powder about 60 orders is carried out micronizing, make the superfines about 500 orders, use desiccant P 2O 5Carry out close drying, dry back water content gets final product in the glue shell of packing into below 4%.
Advantage of the present invention:
(1) American ginseng capsule of the present invention, in the glue shell, be added with biocatalyzer, impel that macromolecular starch is transformed into micromolecular monosaccharide in the Radix Panacis Quinquefolii of capsule core material, this has just more increased the health care usefulness of American ginseng capsule, this also is that prior art (1) institute is incomparable, and prior art (3) is unexistent.
(2) capsule core material is about 500 orders, and water content is less than 4% American Ginseng powder, do not lump, loose, be absorbed by the body easily.Through zoopery, the absorbance of American Ginseng powder is brought up to 10% by original 6%.
(3), adopted and used desiccant P to the dried of capsule core material American Ginseng powder 2O 2Close drying need not reduce pressure and evacuation.So method of the present invention is simply suitable, and guaranteed that the original color of Radix Panacis Quinquefolii is not wandered away in the capsule.Dried powder does not lump, loose, packing easily.
(4) American ginseng capsule of the present invention contains the capsule core material of the little ultra-fine American Ginseng powder of enzyme-added glue shell and water content, has dynamical medical care effect, and taking convenience is absorbed by the body again easily, so it is a kind of comparatively ideal Radix Panacis Quinquefolii Chinese patent medicine.
Embodiment:
Capsule core material: get Radix Panacis Quinquefolii, Radix Panacis Quinquefolii contains total Saponin, volatile oil, starch, protein, organic acid, wherein content of starch is 30%.
The glue shell: the quantity according to required preparation glue shell, take by weighing gelatin, glycerol, agar, food coloring, ethylparaben and biocatalyzer in proportion, wherein biocatalyzer is got α-Dian Fenmei, and content is the 71.7 microlitre/grams (μ l/g) of glue shell.
Preparation process:
1. by above-mentioned content preparation glue shell.
2. pulverizing Radix Panacis Quinquefolii, be crushed to 60 orders after, carry out micronizing again, until being crushed to about 500 orders.
3. American Ginseng powder carries out dried: use desiccant P 2O 5Carry out close drying.
4. with the American Ginseng powder after the dried, load in the glue shell, so far make American ginseng capsule.
The above-mentioned American ginseng capsule of making the experiment proved that human body is had good medical treatment and health-care effect really.

Claims (3)

1. superfined American ginseng capsule, comprise in glue shell and the glue shell capsule core material is housed, wherein the glue shell contains gelatin, glycerol, agar, food coloring and ethylparaben, and capsule core material is an American Ginseng powder, it is characterized in that the glue shell also contains biocatalyzer; Capsule core material is the American Ginseng powder of water content about less than 4% 500 orders.
2. the preparation method of a superfined American ginseng capsule prepares the glue shell earlier, pulverizes Radix Panacis Quinquefolii, again American Ginseng powder is packed in the shell through dried, it is characterized in that American Ginseng powder through micronizing, the Radix Panacis Quinquefolii powder of making about 500 is last, uses desiccant P 2O 5After carrying out the close drying processing, in the packing glue shell.
3. according to the superfined American ginseng capsule of claim 1, it is characterized in that the biocatalyzer that the glue shell contains is a α-Dian Fenmei, or beta amylase, or isoamylase, or pectase, or saccharifying enzyme.
CN 97125218 1997-12-30 1997-12-30 Superfined American ginseng capsule and preparation thereof Expired - Lifetime CN1102404C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 97125218 CN1102404C (en) 1997-12-30 1997-12-30 Superfined American ginseng capsule and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 97125218 CN1102404C (en) 1997-12-30 1997-12-30 Superfined American ginseng capsule and preparation thereof

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CN1185968A CN1185968A (en) 1998-07-01
CN1102404C true CN1102404C (en) 2003-03-05

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100387242C (en) * 2004-12-01 2008-05-14 赵景辉 American ginseng and royal jelly soft capsule
CN103834066B (en) * 2014-03-05 2015-07-22 中国科学院青岛生物能源与过程研究所 Low-viscosity starch glue for preparing starch capsules as well as preparation method and application of low-viscosity starch glue
CN105030865B (en) * 2015-08-18 2018-06-19 深圳市盛元堂生物科技有限公司 A kind of American Ginseng super-micro wall-broken breaking method
CN106074450A (en) * 2016-06-27 2016-11-09 嘉兴杰顺工业设计有限公司 The bioactivity protective technique prepared for medical material superfine powder

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Applicant after: Only Co., Ltd., Shanghai Jiantong Univ.

Applicant before: Shanghai Jiaoda Only Biologic Products Co., Ltd.

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: SHANGHAI JIAODA ONLY BIOLOGIC PRODUCTS CO., LTD. TO: SJTU LP CORP.

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Granted publication date: 20030305