CN110226994A - A kind of nasal cavity bracket and preparation method thereof - Google Patents
A kind of nasal cavity bracket and preparation method thereof Download PDFInfo
- Publication number
- CN110226994A CN110226994A CN201810182342.8A CN201810182342A CN110226994A CN 110226994 A CN110226994 A CN 110226994A CN 201810182342 A CN201810182342 A CN 201810182342A CN 110226994 A CN110226994 A CN 110226994A
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- China
- Prior art keywords
- rack body
- nasal cavity
- cavity bracket
- bracket according
- radial dimension
- Prior art date
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- 210000003928 nasal cavity Anatomy 0.000 title claims abstract description 75
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 239000003814 drug Substances 0.000 claims abstract description 27
- 229940079593 drug Drugs 0.000 claims abstract description 27
- 230000015556 catabolic process Effects 0.000 claims abstract description 13
- 238000006731 degradation reaction Methods 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims abstract description 13
- 238000007493 shaping process Methods 0.000 claims abstract description 8
- 230000002093 peripheral effect Effects 0.000 claims abstract description 5
- 238000010438 heat treatment Methods 0.000 claims description 14
- 238000001816 cooling Methods 0.000 claims description 9
- 239000000835 fiber Substances 0.000 claims description 6
- 229920000642 polymer Polymers 0.000 claims description 6
- 239000007921 spray Substances 0.000 claims description 6
- 239000000853 adhesive Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 229910003460 diamond Inorganic materials 0.000 claims description 3
- 239000010432 diamond Substances 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 3
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims description 3
- 238000004513 sizing Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 5
- 210000003097 mucus Anatomy 0.000 description 4
- 210000003695 paranasal sinus Anatomy 0.000 description 4
- 208000000592 Nasal Polyps Diseases 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 206010061926 Purulence Diseases 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 208000016366 nasal cavity polyp Diseases 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 229920001610 polycaprolactone Polymers 0.000 description 2
- 206010039083 rhinitis Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000032034 Increased viscosity of nasal secretion Diseases 0.000 description 1
- 229920000715 Mucilage Polymers 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004081 cilia Anatomy 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000013129 endoscopic sinus surgery Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000012667 polymer degradation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0618—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The present invention provides a kind of nasal cavity bracket and preparation method thereof, nasal cavity bracket is for medicament-carried in nasal cavity, nasal cavity bracket includes: rack body, the rack body is formed as the column of both ends open, the peripheral wall of the rack body is formed as latticed, the radial dimension at rack body middle part in its axial direction is less than the radial dimension at both ends in its axial direction, and the rack body is formed as degradation material part, and the drug is sprayed on the rack body.Nasal cavity bracket according to an embodiment of the present invention, it is less than its axially upper radial dimension of column in both ends by the radial dimension that rack body is processed into axial upper middle part, rack body is by degradation material machine-shaping, drug is sprayed on rack body, the nasal cavity supporting structure is simple, supporting role is strong, and after drug release, nasal cavity bracket is degradable.
Description
Technical field
The present invention relates to a kind of brackets, more particularly, to a kind of nasal cavity bracket and preparation method thereof.
Background technique
Nasal sinus is the sclerotin chamber of multiple gassiness around nasal cavity, they are communicated with tubule with nasal cavity.Once because viral, thin
The invasion of bacterium or the stimulation of foreign matter, causing limpid mucilage secretion to become, purulence is thick or cilium loses the pulsation for having rule rate, all can
The feeling that the thick nasal mucus of purulence or nasal mucus are flow backwards is generated, and is led to rhinitis or nose film swelling, can all make these tubular occultations.When these
When tubular occultation, just influences whether that nasal cavity mucus remains in a standstill in nasal sinus, influence to discharge.If will be evolved into not as good as morning diagnosis and treatment
There is nasal polyp for nasosinusitis, allergic rhinitis or other rhinitis, serious person.The treatment method of nasal polyp has traditional nose at present
The methods of chamber administration, functional endoscopic sinus surgery.
The nasal cavity bracket of the prior art can only play the role of drug release, but mucous membrane is more in nasal cavity, general to grow up
People about secretes 1 liter of mucus daily, the humidity inside nasal cavity and nasal sinus is maintained by these mucus, while adsorbing in air
Dust and foreign matter, to protect the health of respiratory tract, these mucous membranes can be entered by esophagus stomach discharge or by nostril row
Out, drug will soon be excreted, and can not achieve continuous action, and the nasal cavity support intensity of the prior art is low, cannot drop
Solution.
Summary of the invention
In view of this, the present invention provides a kind of nasal cavity bracket.
The present invention also provides a kind of preparation methods of nasal cavity bracket.
In order to solve the above technical problems, the invention adopts the following technical scheme:
The preparation method of the nasal cavity bracket of embodiment is used for medicament-carried in nasal cavity, nasal cavity according to a first aspect of the present invention
Bracket includes:
Rack body, the rack body are formed as the column of both ends open, and the peripheral wall of the rack body is formed as net
The radial dimension of trellis, rack body middle part in its axial direction is less than the radial dimension at both ends in its axial direction, the branch
Frame ontology is formed as degradation material part, and the drug is sprayed on the rack body.
Further, the rack body is formed as the axial ends from the rack body into the rack body
The column that portion's radial dimension is gradually reduced.
Further, the rack body is formed as from the neighbouring axial end positions of the rack body to the bracket
The cylinder that the middle part radial dimension of ontology is gradually reduced.
Further, the diamond that the grid is identical by row's size and apex angle is connected forms.
Further, the radial dimension of the grid each edge is 0.08mm-0.09mm.
Further, the degradation material is high molecular polymer.
Further, the high molecular polymer is one of PLGA, PGA, PDLLA, PCL.
The preparation method of the nasal cavity bracket of embodiment includes the following steps: according to a second aspect of the present invention
Fiber filament is put into mold to be woven into latticed ring support ontology by step S1；
The rack body and the mold are placed on progress pre-setting heat treatment in vacuum oven by step S2；
The rack body is taken out from the mold, and cuts the ending connecting pin of the rack body by step S3；
The rack body is put into setting tooling by step S4, and the rack body and the setting tooling are put
It sets and carries out shaping heat treatment in a vacuum drying oven；
Step S5, the cooling rack body and the setting tooling, and by the rack body from the setting tooling
Interior taking-up；
Step S6 is bonded using point of intersection of the adhesive to the rack body；
Step S7 sprays medication coat on the rack body；
The rack body is placed on vacuum oven to dry the medication coat by step S8.
Further, the setting tooling is formed as column, is defined in the setting tooling along its circumferentially extending and edge
Axially through annular positioning groove, the radial dimension at annular positioning groove middle part in its axial direction is less than both ends in its axial direction
Radial dimension, the fiber filament, which is placed in the annular positioning groove, forms the rack body.
Further, the annular positioning groove be formed as from the axial ends of the setting tooling to middle part radial dimension by
Decrescence small annular.
Further, the annular positioning groove is formed as from the neighbouring axial ends of the setting tooling to middle part radial ruler
The very little annular being gradually reduced.
Further, in the step S4, the temperature of the pre-setting heat treatment is 40 DEG C -90 DEG C, the pre-setting
The time of heat treatment is 10min-60min.
Further, in the step S5, the cooling rack body of air-cooler is used.
Further, in the step S5, the cooling temperature of the rack body is 0 DEG C -15 DEG C.
Further, in the step S6, the rack body is placed on progress intersection point bonding under magnifying glass.
Further, in the step S7, the rack body is using medication coat described in ultrasonic spray.
Further, in the step S8, drying temperature of the rack body in the vacuum oven is 30
℃-40℃。
The advantageous effects of the above technical solutions of the present invention are as follows:
Nasal cavity bracket according to an embodiment of the present invention is small by the radial dimension that rack body is processed into axial upper middle part
In the upper radial dimension of column in both ends of its axial direction, for rack body by degradation material machine-shaping, drug is sprayed on bracket sheet
On body, the nasal cavity supporting structure is simple, and supporting role is strong, and after drug release, nasal cavity bracket is degradable.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the setting tooling of nasal cavity bracket in the prior art；
Fig. 2 is the axial section of Fig. 1；
Fig. 3 is the structural schematic diagram of nasal cavity bracket in the prior art；
Fig. 4 is a structural schematic diagram according to nasal cavity bracket in the embodiment of the present invention；
Fig. 5 is another structural schematic diagram according to nasal cavity bracket in the embodiment of the present invention.
Fig. 6 is the structural schematic diagram according to the rack body of nasal cavity bracket in the embodiment of the present invention；
Fig. 7 is a structural schematic diagram according to setting tooling in the embodiment of the present invention；
Fig. 8 is the axial section of Fig. 7；
Fig. 9 is another structural schematic diagram according to setting tooling in the embodiment of the present invention；
Figure 10 is the axial section of Fig. 9.
Appended drawing reference:
Nasal cavity bracket 100；Rack body 10；Setting tooling 20；Locating slot 21.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention
Attached drawing, the technical solution of the embodiment of the present invention is clearly and completely described.Obviously, described embodiment is this hair
Bright a part of the embodiment, instead of all the embodiments.Based on described the embodiment of the present invention, ordinary skill
Personnel's every other embodiment obtained, shall fall within the protection scope of the present invention.
The present invention is present inventor based on the fact that made creation.
As depicted in figs. 1 and 2, setting tooling 1 can process the nasal cavity bracket 2 obtained in Fig. 3 according to prior art, should
Nasal cavity support intensity is low, and support force is small.
Based on above-mentioned technical problem of the existing technology, present inventor is directed to the nasal cavity bracket 2 of the prior art
It is studied and has been improved with nasal cavity bracket preparation method, propose a kind of preparation suitable for nasal cavity bracket 100 and nasal cavity bracket
Method.
Nasal cavity bracket 100 according to an embodiment of the present invention is specifically described in conjunction with attached drawing first below.
As shown in Figure 4 and Figure 5, the nasal cavity bracket 100 of embodiment is used to carry in nasal cavity according to a first aspect of the present invention
Drug, nasal cavity bracket 100 include rack body 10.
Specifically, rack body 10 is formed as the column of both ends open, the peripheral wall of rack body 10 is formed as latticed,
The radial dimension at the middle part in its axial direction of rack body 10 is less than the radial dimension at both ends in its axial direction, the formation of rack body 10
For degradation material part, drug is sprayed on rack body 10.
In other words, for nasal cavity bracket 100 for medicament-carried in nasal cavity, nasal cavity bracket 100 includes rack body 10,
In, rack body 10 is formed as the column of both ends open, as shown in fig. 6, the peripheral wall of rack body 10 is formed as latticed, bracket
The radial dimension at the middle part in its axial direction of ontology 10 is less than the radial dimension at both ends in its axial direction, and rack body 10 can held
When compression compression deformation, stronger radial support intensity is provided, resists from tissue edema bring pressure, keeps nasal sinus position not
Blocking, airflow smooth, rack body 10 is by degradation material machine-shaping, and drug is sprayed on rack body 10, rack body
10 are placed in nasal cavity, and after drug release on rack body 10, rack body 10 can degrade.
Nasal cavity bracket 100 according to an embodiment of the present invention as a result, by the way that rack body 10 is processed into axial upper middle part
Radial dimension is less than its axially upper radial dimension of column in both ends, and rack body 10 is by degradation material machine-shaping, drug
It is sprayed on rack body 10,100 structure of nasal cavity bracket is simple, and supporting role is strong, and after drug release, nasal cavity bracket 100 can
Degradation.
Some specific embodiments according to the present invention, as shown in figure 4, rack body 10 can be formed as from rack body 10
The column that is gradually reduced to the middle part radial dimension of rack body 10 of axial ends, this kind of structural strength height, it is ensured that foot
Enough strong support forces.
According to one embodiment of present invention, as shown in figure 5, rack body 10 can be formed as the neighbour from rack body 10
The paraxial cylinder being gradually reduced to end positions to the middle part radial dimension of rack body 10, which can be in compressive deformation
When, stronger radial support intensity is provided.
Preferably, the diamond that grid is identical by row's size and apex angle is connected forms, and the shape of grid can also basis
Specifically need for other shapes.
Further, the radial dimension of grid each edge can be 0.08mm-0.09mm.
According to one embodiment of present invention, degradation material can be high molecular polymer.
Further, one of materials such as high molecular polymer PLGA, PGA, PDLLA, PCL, these polymer
Degradation cycle is -60 days 30 days.
That is, the drug on rack body 10 discharges completely, nasal cavity bracket 100 completes support period, nasal cavity
Bracket 100 degrades and is excreted.
To sum up, nasal cavity bracket 100 according to an embodiment of the present invention, in rack body 10 is processed into axial direction
The radial dimension in portion is less than its axially upper radial dimension of column in both ends, rack body 10 by degradation material machine-shaping,
Drug is sprayed on rack body 10, and 100 structure of nasal cavity bracket is simple, and supporting role is strong, after drug release, nasal cavity bracket
100 is degradable.
The preparation method of a kind of nasal cavity bracket 100 of embodiment according to a second aspect of the present invention, includes the following steps:
Fiber filament is put into mold 20 to be woven into latticed ring support ontology 10 by step S1；
Rack body 10 and mold 20 are placed on progress pre-setting heat treatment in vacuum oven by step S2；
Rack body 10 is taken out from mold 20, and cuts the ending connecting pin of rack body 10 by step S3；
Rack body 10 is put into setting tooling by step S4, and rack body 10 and setting tooling are placed on vacuum
Heat treatment is carried out shaping in drying box；
Step S5, cooling holder ontology 10 and setting tooling, and rack body 10 is taken out out of setting tooling；
Step S6 is bonded using point of intersection of the adhesive to rack body 10；
Step S7 sprays medication coat on rack body 10；
Rack body 10 is placed on vacuum oven to dry medication coat by step S8.
The preparation method of nasal cavity bracket 100 according to an embodiment of the present invention as a result, easy to implement, easy to operate, pre-setting
Heat treatment and sizing heat treatment make nasal cavity bracket 100 obtain powerful radial support.
Some specific embodiments according to the present invention, setting tooling 20 are formed as column, define edge in setting tooling 20
Its circumferentially extend and along axially through annular positioning groove 21, annular positioning groove 21 in its axial direction middle part radial dimension be less than
The radial dimension at both ends in its axial direction, fiber filament, which is placed in annular positioning groove 21, forms rack body 10.
According to one embodiment of present invention, as shown in Figure 7 and Figure 8, annular positioning groove 21 can be formed as from sizing work
Fill the annular that 20 axial ends is gradually reduced to middle part radial dimension.
According to still another embodiment of the invention, as shown in Figure 9 and Figure 10, annular positioning groove 21 is formed as from setting tooling
The annular that 20 neighbouring axial ends is gradually reduced to middle part radial dimension.
Preferably, in step s 4, pre-setting heat treatment temperature be 40 DEG C -90 DEG C, pre-setting heat treatment time be
10min-60min。
Optionally, in step s 5, using air-cooler cooling holder ontology 10.
In one embodiment of the invention, in step s 5, the cooling temperature of rack body 10 can be 0 DEG C -15 DEG C.
Preferably, in step s 6, rack body 10 is placed on progress intersection point bonding under magnifying glass, bonding is convenient.
According to one embodiment of present invention, in the step s 7, rack body 10 uses ultrasonic spray medication coat, surpasses
Sound wave spraying is uniform.
Preferably, in step s 8, drying temperature of the rack body 10 in vacuum oven is 30 DEG C -40 DEG C.
The above is a preferred embodiment of the present invention, it is noted that for those skilled in the art
For, without departing from the principles of the present invention, it can also make several improvements and retouch, these improvements and modifications
It should be regarded as protection scope of the present invention.
Claims (17)
1. a kind of nasal cavity bracket, for medicament-carried in nasal cavity characterized by comprising
Rack body, the rack body are formed as the column of both ends open, and the peripheral wall of the rack body is formed as latticed,
The radial dimension at rack body middle part in its axial direction is less than the radial dimension at both ends in its axial direction, the rack body
Be formed as degradation material part, the drug is sprayed on the rack body.
2. nasal cavity bracket according to claim 1, which is characterized in that the rack body is formed as from the rack body
The column that is gradually reduced to the middle part radial dimension of the rack body of axial ends.
3. nasal cavity bracket according to claim 1, which is characterized in that the rack body is formed as from the rack body
The cylinder that is gradually reduced to the middle part radial dimension of the rack body of neighbouring axial end positions.
4. nasal cavity bracket according to claim 1, which is characterized in that the grid is identical by row's size and apex angle is connected
Diamond composition.
5. nasal cavity bracket according to claim 4, which is characterized in that the radial dimension of the grid each edge is
0.08mm-0.09mm。
6. nasal cavity bracket according to claim 1, which is characterized in that the degradation material is high molecular polymer.
7. nasal cavity bracket according to claim 6, which is characterized in that the high molecular polymer be PLGA, PGA,
One of PDLLA, PCL.
8. a kind of preparation method of nasal cavity bracket, which comprises the steps of:
Fiber filament is put into mold to be woven into latticed ring support ontology by step S1；
The rack body and the mold are placed on progress pre-setting heat treatment in vacuum oven by step S2；
The rack body is taken out from the mold, and cuts the ending connecting pin of the rack body by step S3；
The rack body is put into setting tooling by step S4, and the rack body and the setting tooling are placed on
Heat treatment is carried out shaping in vacuum oven；
Step S5, the cooling rack body and the setting tooling, and the rack body is taken out of described setting tooling
Out；
Step S6 is bonded using point of intersection of the adhesive to the rack body；
Step S7 sprays medication coat on the rack body；
The rack body is placed on vacuum oven to dry the medication coat by step S8.
9. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that the setting tooling is formed as column
Shape, define in the setting tooling along its circumferentially extending and along axially through annular positioning groove, the annular positioning groove exists
Axially above for the radial dimension at middle part less than the radial dimension at both ends in its axial direction, it is fixed that the fiber filament is placed on the annular for it
The rack body is formed in the slot of position.
10. the preparation method of nasal cavity bracket according to claim 9, which is characterized in that the annular positioning groove is formed as
The annular being gradually reduced from the axial ends of the setting tooling to middle part radial dimension.
11. the preparation method of nasal cavity bracket according to claim 9, which is characterized in that the annular positioning groove is formed as
The annular being gradually reduced from the neighbouring axial ends of the setting tooling to middle part radial dimension.
12. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that described pre- in the step S4
The temperature of sizing heat treatment is 40 DEG C -90 DEG C, and the time of the pre-setting heat treatment is 10min-60min.
13. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that in the step S5, use is cold
The cooling rack body of blower.
14. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that in the step S5, the branch
The cooling temperature of frame ontology is 0 DEG C -15 DEG C.
15. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that, will be described in the step S6
Rack body is placed on progress intersection point bonding under magnifying glass.
16. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that in the step S7, the branch
Frame ontology is using medication coat described in ultrasonic spray.
17. the preparation method of nasal cavity bracket according to claim 8, which is characterized in that in the step S8, the branch
Drying temperature of the frame ontology in the vacuum oven is 30 DEG C -40 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810182342.8A CN110226994A (en) | 2018-03-06 | 2018-03-06 | A kind of nasal cavity bracket and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810182342.8A CN110226994A (en) | 2018-03-06 | 2018-03-06 | A kind of nasal cavity bracket and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110226994A true CN110226994A (en) | 2019-09-13 |
Family
ID=67861770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810182342.8A Pending CN110226994A (en) | 2018-03-06 | 2018-03-06 | A kind of nasal cavity bracket and preparation method thereof |
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| CN (1) | CN110226994A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111529150A (en) * | 2020-04-28 | 2020-08-14 | 东南大学苏州医疗器械研究院 | Sinus duct stent and preparation method thereof |
| CN111544168A (en) * | 2020-05-13 | 2020-08-18 | 东华大学 | Integrated woven covered stent edge folding process |
| CN114701104A (en) * | 2022-04-29 | 2022-07-05 | 深圳市库珀科技发展有限公司 | Covered stent and monofilament pressing device thereof |
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| CN114701104A (en) * | 2022-04-29 | 2022-07-05 | 深圳市库珀科技发展有限公司 | Covered stent and monofilament pressing device thereof |
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