CN110204675A - A method of for making the composition and production locating pad of locating pad - Google Patents
A method of for making the composition and production locating pad of locating pad Download PDFInfo
- Publication number
- CN110204675A CN110204675A CN201910366203.5A CN201910366203A CN110204675A CN 110204675 A CN110204675 A CN 110204675A CN 201910366203 A CN201910366203 A CN 201910366203A CN 110204675 A CN110204675 A CN 110204675A
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- Prior art keywords
- locating pad
- parts
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- packaging bag
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/48—Polyethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
- C08L75/04—Polyurethanes
- C08L75/08—Polyurethanes from polyethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2110/00—Foam properties
- C08G2110/0083—Foam properties prepared using water as the sole blowing agent
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
Abstract
The method of the composition and production locating pad that the invention discloses a kind of for making locating pad, wherein, the composition includes: polyether polyol 90-110 parts by weight, isocyanates 85-100 parts by weight, catalyst 1-5 parts by weight, foaming agent 1-5 parts by weight, foam stabiliser 5-10 parts by weight, nitrogen-doped graphene 0.5-2 parts by weight, modified halloysite nanotubes 1-3 parts by weight.The present invention makes performance of the locating pad in terms of the rate of collapsing, shore hardness be improved by the way that nitrogen-doped graphene is added, is modified halloysite nanotubes.
Description
Technical field
The invention belongs to medical instruments fields, specifically, being related to a kind of composition for making locating pad and production
The method of locating pad.
Background technique
Malignant tumour has seriously endangered the life and health of the mankind, and treatment method is also always focus concerned by people.Mesh
Before, the treatment means of malignant tumour mainly have operative treatment, radiotherapy (radiotherapy), chemotherapy (chemotherapy), freezing to control
Treatment and thermotherapy etc..Because its indication is than broad, selectivity is larger for radiotherapy, it has also become current oncotherapy is most effective most universal
One of method.
The maximum purpose of radiotherapy is that control radiological dose focuses on diseased region to the maximum extent, and normal surrounding tissue
Or organ is few by or from unnecessary irradiation.In order to avoid the influence of breathing or position etc., normal cell is caused to repair
Multiple damage, modern tumour accurate radiotherapy technology are developed rapidly.In accurate radiotherapy, the repeated and accurate of position is put
Property be ensure radiotherapeutic effect one of key factor.
Positioning method is to put the important guarantee of position accuracy and repeatability.The radiotherapy localization being clinically applied at present
Product mainly has vacuum pad, body mould and polyurethane foam pad etc..But there are still some problems for these products.Vacuum pad is deposited
In easy gas leakage, it is not easy the problems such as storing for a long time, is bad with patient's stickiness, while it is more complex using operating process.Body mould is
A kind of special thermoplastic macromolecule material, the material itself have certain morphotropism, not good enough to the fixed effect of patient,
And pendulum position repeatability is also undesirable.Polyurethane foam pad is because can effectively solve the problem that body mould and vacuum pad positioning moulding are inaccurate, pasting
The problems such as conjunction property is bad, has obtained the concern of people, but existing commercial polyurethane foam pad is during the reaction due to heat release
The problems such as temperature is excessively high, causes human body comfort poor, and there are used catalysts poisonous and harmful, products obtained therefrom collapses rate is high.
In view of this present invention is specifically proposed.
Summary of the invention
The invention solves the first technical problem be to overcome the deficiencies of the prior art and provide it is a kind of for making positioning
The composition of pad, to solve, existing foam locating pad exothermic heat of reaction temperature is high, rate of collapsing is high, the poisonous and hazardous technology of catalyst
Problem.
The invention solves the second technical problem be to overcome the deficiencies of the prior art and provide a kind of locating pad that makes
Method, to solve the technical problem of user experience effect difference.
To solve above-mentioned first technical problem, the present invention is using the basic conception of technical solution:
The present invention provides a kind of for making the composition of locating pad, comprising:
Polyether polyol 90-110 parts by weight
Isocyanates 85-100 parts by weight
Catalyst 1-5 parts by weight
Foaming agent 1-5 parts by weight
Foam stabiliser 5-10 parts by weight
Nitrogen-doped graphene 0.5-2 parts by weight
Modified halloysite nanotubes 1-3 parts by weight.
Further, composition includes:
Polyether polyol 90-110 parts by weight
Isocyanates 85-100 parts by weight
Catalyst 1-5 parts by weight
Foaming agent 1-5 parts by weight
Foam stabiliser 5-10 parts by weight
Nitrogen-doped graphene 0.5-2 parts by weight
Modified halloysite nanotubes 1-3 parts by weight
Cellulose nanocrystal body 0.5-1.5 parts by weight.
Further, modified halloysite nanotubes are coupling agent modified halloysite nanotubes, intercalation modifying galapectite nanometer
Pipe, surface coating modification halloysite nanotubes, radical modification halloysite nanotubes, surfactant-modified galapectite nanometer
The combination of one or more of pipe.
Further, the catalyst is the combination of one or more of polyalcohol, amine and ethers catalyst；It is preferred that
, polyalcohol is dipropylene glycol, and amines catalyst is dimethylethanolamine, and ethers catalyst is bis- (dimethylamino ethyl) ethers.
Further, the foam stabiliser by the polysiloxanes such as methyl-silicone oil, modified silicon oil one or more of groups
It closes.
Further, the polyether polyol by degree of functionality >=2 polyether polyol one or more of combinations.
Further, the isocyanates by degree of functionality >=2 isocyanates one or more combination；Preferably, institute
Stating isocyanates is one or more of 4-4 '-di-2-ethylhexylphosphine oxide phenyl isocyanate, poly methylene poly phenyl poly isocyanate
Combination.
To solve above-mentioned second technical problem, the present invention is using the basic conception of technical solution:
The present invention also provides the methods of a kind of as above any composition production locating pad, comprising:
(1) composition is mixed, obtains mixture；
(2) mixture that step (1) obtains is poured into curing molding in mold, obtains locating pad.
Further, in step (1), first by polyether polyol, catalyst, foaming agent, foam stabiliser, N doping graphite
Alkene, modified halloysite nanotubes mixing, obtain A material, and A material is mixed with isocyanates, obtain mixture；Preferably, step (1)
In, first by polyether polyol, catalyst, foaming agent, foam stabiliser, nitrogen-doped graphene, modified halloysite nanotubes, fibre
Plain nanocrystal mixing is tieed up, A material is obtained, A material is mixed with isocyanates, obtains mixture.
Further, in step (2), the mixture that step (1) obtains is poured into packaging bag, packaging bag is sealed after filling
Mouthful, the privileged site of locating pad user acts in packaging bag, constitutes mold after deforming packaging bag.
Specifically, locating pad of the invention is human body locating pad, and locating pad user is user.
After adopting the above technical scheme, compared with the prior art, the invention has the following beneficial effects:
1, the present invention keeps locating pad hard in the rate of collapsing, shore by the way that nitrogen-doped graphene is added, is modified halloysite nanotubes
The performance of degree aspect is improved.
2, the present invention makes locating pad by the way that nitrogen-doped graphene, modified halloysite nanotubes and Cellulose nanocrystal body is added
Performance in terms of the rate of collapsing, shore hardness is had been further upgraded.
3, locating pad used catalyst of the invention is nontoxic, low in cost.
4, locating pad preparation process of the invention is simple, in preparation process exothermic temperature it is lower≤55 DEG C, it is resistance to meet human body
By temperature, patient's usage comfort is good.
5, locating pad of the invention is collapsed, and rate is lower, and rate≤3% of collapsing after placing one month, product stability is good, uses
Service life is long.
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be to the technology in embodiment
Scheme is clearly and completely described, and the following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
One whole body human body locating pad of embodiment
1, raw material and formula composition are as follows:
Composition of raw materials
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil, nitrogen-doped graphene and
Modified halloysite nanotubes mixing, obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 52.8 DEG C.
Two whole body human body locating pad of embodiment
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 2 |
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil, nitrogen-doped graphene and
Modified halloysite nanotubes mixing, obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 52.7 DEG C.
Three whole body human body locating pad of embodiment
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Nitrogen-doped graphene | 2 |
| Modified halloysite nanotubes | 3 |
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil, nitrogen-doped graphene and
Modified halloysite nanotubes mixing, obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 52.5 DEG C.
Example IV whole body human body locating pad
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 1.5 |
| Cellulose nanocrystal body | 1.5 |
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil, nitrogen-doped graphene, change
Property halloysite nanotubes and Cellulose nanocrystal body mixing, obtain A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 50.8 DEG C.
Five whole body human body locating pad of embodiment
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 2 |
| Cellulose nanocrystal body | 1 |
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil, nitrogen-doped graphene, change
Property halloysite nanotubes and Cellulose nanocrystal body mixing, obtain A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 50.6 DEG C.
Six whole body human body locating pad of embodiment
1, raw material and formula composition are as follows:
Composition of raw materials
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil, nitrogen-doped graphene, change
Property halloysite nanotubes and Cellulose nanocrystal body mixing, obtain A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 50.4 DEG C.
One whole body human body locating pad of comparative example
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
2, preparation flow is as follows:
A, block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water and modified silicon oil are mixed, obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 62.8 DEG C.
Two whole body human body locating pad of comparative example
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Nitrogen-doped graphene | 1 |
2, preparation flow is as follows:
A, block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil and nitrogen-doped graphene is mixed
It closes, obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 60.8 DEG C.
Three whole body human body locating pad of comparative example
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Modified halloysite nanotubes | 1.5 |
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil and modified galapectite nanometer
Pipe mixing obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 60.5 DEG C.
Four whole body human body locating pad of comparative example
1, raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Block copolymerization polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 90 |
| Bis- (dimethylamino ethyl) ethers | 3 |
| Water | 2 |
| Modified silicon oil | 6 |
| Cellulose nanocrystal body | 1.5 |
2, preparation flow is as follows:
A, by block copolymerization polyether polyol, bis- (dimethylamino ethyl) ethers, water, modified silicon oil and Cellulose nanocrystal body
Mixing obtains A material.
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material reacts in bag to be packaged
Curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the whole body human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 60.2 DEG C.
Test example 1
This test example tests human body locating pad the collapsing after room temperature is stood 30 days of embodiment 1-6 and comparative example 1-4
Rate and shore hardness, as a result as follows:
As can be seen from the above table, the present invention makes locating pad exist by the way that nitrogen-doped graphene is added, is modified halloysite nanotubes
The performance in terms of rate, shore hardness of collapsing is improved.The present invention is received by the way that nitrogen-doped graphene is added, is modified galapectite
Mitron and Cellulose nanocrystal body make performance of the locating pad in terms of the rate of collapsing, shore hardness have been further upgraded.
The medical accurate radiotherapy foam human body locating pad of seven incidence of embodiment
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 3 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil, nitrogen-doped graphene
With modified halloysite nanotubes mixing, A material is obtained；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 52.5 DEG C；
The medical accurate radiotherapy foam human body locating pad of eight incidence of embodiment
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 2 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil, nitrogen-doped graphene
With modified halloysite nanotubes mixing, A material is obtained；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 52.3 DEG C；
The medical accurate radiotherapy foam human body locating pad of nine incidence of embodiment
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Nitrogen-doped graphene | 2 |
| Modified halloysite nanotubes | 3 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil, nitrogen-doped graphene
With modified halloysite nanotubes mixing, A material is obtained；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 52.1 DEG C；
The medical accurate radiotherapy foam human body locating pad of ten incidence of embodiment
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 3 |
| Cellulose nanocrystal body | 1 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil, N doping graphite
Alkene, modified halloysite nanotubes and the mixing of Cellulose nanocrystal body, obtain A material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 50.1 DEG C；
The medical accurate radiotherapy foam human body locating pad of 11 incidence of embodiment
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Nitrogen-doped graphene | 1 |
| Modified halloysite nanotubes | 2 |
| Cellulose nanocrystal body | 1.5 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil, N doping graphite
Alkene, modified halloysite nanotubes and the mixing of Cellulose nanocrystal body, obtain A material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 50.0 DEG C；
The medical accurate radiotherapy foam human body locating pad of 12 incidence of embodiment
1. raw material and formula composition are as follows:
Composition of raw materials
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil, N doping graphite
Alkene, modified halloysite nanotubes and the mixing of Cellulose nanocrystal body, obtain A material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 50.1 DEG C；
The medical accurate radiotherapy foam human body locating pad of five incidence of comparative example
1. raw material and formula composition are as follows:
Composition of raw materials
2. preparation flow is as follows:
A, epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water and methyl-silicone oil are mixed, obtains A
Material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 61.2 DEG C；
The medical accurate radiotherapy foam human body locating pad of six incidence of comparative example
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Nitrogen-doped graphene | 1 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil and N doping graphite
Alkene mixing obtains A material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 60.5 DEG C；
The medical accurate radiotherapy foam human body locating pad of seven incidence of comparative example
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Modified halloysite nanotubes | 3 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil and modified galapectite
Nanotube mixing obtains A material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 60.3 DEG C；
The medical accurate radiotherapy foam human body locating pad of eight incidence of comparative example
1. raw material and formula composition are as follows:
Composition of raw materials
| Material name | Quality/g |
| Epoxy ethane-epoxy propane polyether polyol | 100 |
| Poly methylene poly phenyl poly isocyanate | 100 |
| Dimethylethanolamine | 2 |
| Water | 2 |
| Methyl-silicone oil | 5 |
| Cellulose nanocrystal body | 1 |
2. preparation flow is as follows:
A, by epoxy ethane-epoxy propane polyether polyol, dimethylethanolamine, water, methyl-silicone oil and cellulose nanometer
Crystal mixing obtains A material；
B, poly methylene poly phenyl poly isocyanate is poured into A material, shakes up 95s, pours into water-proof ventilating packaging bag, sealed
Mouthful；
C, the mixed material in water-proof ventilating packaging bag is uniformly paved, material is made uniformly to fill up packaging bag.
D, locating personnel's neck lies low in the packaging bag for being paved with material, waiting for quietly 15 minutes, and material occurs in bag to be packaged
React curing molding.
E, after locating pad molding, locating personnel stands up to leave, and obtains the incidence human body locating pad of custom-made by size.
Wherein, during foaming and setting, real-time monitoring exothermic heat of reaction temperature, maximum temperature is 60.2 DEG C；
Test example 2
This test example tests human body locating pad the collapsing after room temperature is stood 30 days of embodiment 7-12 and comparative example 5-8
Rate and shore hardness, as a result as follows:
As can be seen from the above table, the present invention makes locating pad exist by the way that nitrogen-doped graphene is added, is modified halloysite nanotubes
The performance in terms of rate, shore hardness of collapsing is improved.The present invention is received by the way that nitrogen-doped graphene is added, is modified galapectite
Mitron and Cellulose nanocrystal body make performance of the locating pad in terms of the rate of collapsing, shore hardness have been further upgraded.
The above is only presently preferred embodiments of the present invention, is not intended to limit the present invention in any form, though
So the present invention has been disclosed as a preferred embodiment, and however, it is not intended to limit the invention, any technology people for being familiar with this patent
Member without departing from the scope of the present invention, when the technology contents using above-mentioned prompt make a little change or modification
For the equivalent embodiment of equivalent variations, but anything that does not depart from the technical scheme of the invention content, according to the technical essence of the invention
Any simple modification, equivalent change and modification to the above embodiments, in the range of still falling within the present invention program.
Claims (10)
1. a kind of for making the composition of locating pad characterized by comprising
Polyether polyol 90-110 parts by weight
Isocyanates 85-100 parts by weight
Catalyst 1-5 parts by weight
Foaming agent 1-5 parts by weight
Foam stabiliser 5-10 parts by weight
Nitrogen-doped graphene 0.5-2 parts by weight
Modified halloysite nanotubes 1-3 parts by weight.
2. according to claim 1 a kind of for making the composition of locating pad characterized by comprising
Polyether polyol 90-110 parts by weight
Isocyanates 85-100 parts by weight
Catalyst 1-5 parts by weight
Foaming agent 1-5 parts by weight
Foam stabiliser 5-10 parts by weight
Nitrogen-doped graphene 0.5-2 parts by weight
Modified halloysite nanotubes 1-3 parts by weight
Cellulose nanocrystal body 0.5-1.5 parts by weight.
3. according to claim 1 a kind of for making the composition of locating pad, which is characterized in that modified galapectite nanometer
Pipe is coupling agent modified halloysite nanotubes, intercalation modifying halloysite nanotubes, surface coating modification halloysite nanotubes, freedom
Base is modified the combination of one or more of halloysite nanotubes, surfactant-modified halloysite nanotubes.
4. according to claim 1 a kind of for making the composition of locating pad, which is characterized in that the catalyst is more
The combination of one or more of first alcohol, amine and ethers catalyst；Preferably, polyalcohol is dipropylene glycol, amines catalyst
For dimethylethanolamine, ethers catalyst is bis- (dimethylamino ethyl) ethers.
5. according to claim 1 a kind of for making the composition of locating pad, which is characterized in that the foam stabiliser
By one or more of combinations of the polysiloxanes such as methyl-silicone oil, modified silicon oil.
6. according to claim 1 a kind of for making the composition of locating pad, which is characterized in that the polyether polyol
By one or more of combinations of the polyether polyol of degree of functionality >=2.
7. according to claim 1 a kind of for making the composition of locating pad, which is characterized in that the isocyanates by
The combination of degree of functionality >=2 isocyanates one or more；Preferably, the isocyanates is 4-4 '-di-2-ethylhexylphosphine oxide isocyanic acid
The combination of one or more of phenyl ester, poly methylene poly phenyl poly isocyanate.
8. a kind of method of composition production locating pad as claimed in claim 1 to 7 characterized by comprising
(1) composition is mixed, obtains mixture；
(2) mixture that step (1) obtains is poured into curing molding in mold, obtains locating pad.
9. a kind of method for making locating pad according to claim 8, which is characterized in that first that polyethers is more in step (1)
First alcohol, catalyst, foaming agent, foam stabiliser, nitrogen-doped graphene, the mixing of modified halloysite nanotubes, obtain A material, A material with
Isocyanates mixing, obtains mixture；Preferably, first that polyether polyol, catalyst, foaming agent, foam is steady in step (1)
Determine agent, nitrogen-doped graphene, modified halloysite nanotubes, the mixing of Cellulose nanocrystal body, obtain A material, A material and isocyanates are mixed
It closes, obtains mixture.
10. a kind of method for making locating pad according to claim 8, which is characterized in that in step (2), by step (1)
Obtained mixture pours into packaging bag, and packaging bag is sealed after filling, and the privileged site of locating pad user acts on packaging bag
On, mold is constituted after deforming packaging bag.
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Application publication date: 20190906 |