CN110169934A - A kind of dual liposomes cosmetics - Google Patents

A kind of dual liposomes cosmetics Download PDF

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Publication number
CN110169934A
CN110169934A CN201910446759.5A CN201910446759A CN110169934A CN 110169934 A CN110169934 A CN 110169934A CN 201910446759 A CN201910446759 A CN 201910446759A CN 110169934 A CN110169934 A CN 110169934A
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Prior art keywords
liposomes
dual
cosmetics
skin
percentage
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CN201910446759.5A
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Chinese (zh)
Inventor
胡清香
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Individual
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Priority to CN201910446759.5A priority Critical patent/CN110169934A/en
Publication of CN110169934A publication Critical patent/CN110169934A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26Aluminium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of dual liposomes cosmetics, the toiletry bag contains following materials in percentage by mass: water 1.2%, propylene glycol 0.5%, glycerol 0.7%, trehalose 0.4%, glycine betaine 0.3%, hydrolecithin 0.6%, sodium carboxymethyl starch 0.5%, acetyl group tetrapeptide -5 0.8%, hydrolytic collagen 1.3%, hyaluronic acid 0.7%, allantoin 0.5%, purslane extract 22.8%, pentapeptide 22.5%, elastin hydrolysis 22.8%, aluminum magnesium silicate 0.2%, Apple cell culture extract 22.8%, 3-o- ethylascorbyl 0.5%, Phenoxyethanol 0.3%, Sensiva SC50 0.6%.A variety of active ingredients is wrapped up in this dual liposomes cosmetics, is promoted blood circulation, the adjustment colour of skin is improved;Securely and reliably, nontoxic to skin, without side-effects, can use everyday.

Description

A kind of dual liposomes cosmetics
Technical field
The present invention relates to a kind of dual liposomes cosmetics, specially technical field of cosmetic preparation.
Background technique
The revolution liposomes technology of international cosmetic osmosis process is technology most top in current cosmetics osmosis process, Be a kind of special liposome various active constituents.This liposome emphasizes " water and oil balance ", can high-effective penetrating to skin Skin basal layer absorbs faster better effect than general skin care item, applies in basic skin care item, keep skin effect more perfect. Dual liposomes is wrapped in moisture and nutrient, and it (is to calculate with nanometer that diameter, which revolutionaryly reduces 1000 times than traditional skin care product, Unit), the gap of pore and corneocyte can be penetrated easily, into deep skin, the absorptivity of skin care item is allowed to improve To 82%, it means that more moisture and nutrient can be absorbed in skin, supplements corium nutrition transmission not to the maximum extent Foot, and remaining fraction nutrient stays on cuticula and protects scattering and disappearing for skin internal moisture, it is more preferable solve skin yearningly and Skin care item of this hungry science and technology, can preferably delaying skin aging.It can be described as problem in skin care history, keep skin real Moisten that full, vigor is unlimited, long-term apply puts the revolutionary invention used on the skin.
Dual liposomes technique for packing can solve the problems, such as that at all product composition is used effectively.This is a kind of special lipid Body is wrapped in the particle of various active constituents.The skin of people is made of one layer of fine and close cell, and cell membrane is to most of life Active substances, especially macromolecular bioactive substance are impermeable.With this technology, skin care ingredient is wrapped in diameter and is In the utricule of 25-30 (reducing 1000 times than traditional skin care product) nanometer, 50 nanometers of horn cell gap is penetrated easily, go directly skin Skin basal layer greatly improves the absorptivity of skin care item, continually supplies skin cell nutritional ingredient, it is made preferably to play beauty Hold skin-care effect;The deficiency of corium nutrition transmission can be supplemented to the maximum extent, and remaining fraction nutrient stays in cutin Scattering and disappearing for skin internal moisture is protected on layer, makes that skin is really moist, full, vigor is unlimited, is used for a long time and has been used this technology Cosmetics and skincare product, can preferably delaying skin aging.
Multiple-factor technique for packing is made using unique production technology, is a kind of colored stemness almost spherical particle, The ingredients such as hyaluronic acid, vitamin C are wrapped up.In massage can partial crushing, slow release decomposites active constituent and tiny Particle supplements the nutrients to skin.
Summary of the invention
The purpose of the present invention is to provide a kind of dual liposomes cosmetics.
To achieve the above object, the invention provides the following technical scheme: a kind of dual liposomes toiletry bag contains following matter Measure percentage raw material: water 1-3%, propylene glycol 0.3-0.8%, glycerol 0.73-1%, trehalose 0.3-1%, glycine betaine 0.3- 0.8%, hydrolecithin 0.3-0.8%, sodium carboxymethyl starch 0.3-0.8%, -5 0.6-1.2% of acetyl group tetrapeptide, hydrolysis glue Former 1.0-1.5%, hyaluronic acid 0.5-1%, allantoin 0.3-1%, purslane extract 20-25%, pentapeptide 20-25%, water Solve elastin laminin 20-25%, aluminum magnesium silicate 0.1-0.5%, Apple cell culture extract 20-25%, 3-o- ethyl Ascorbic acid 0.3-0.8%, Phenoxyethanol 0.2-0.8%, Sensiva SC50 0.3-0.8%.
Further preferably, the dual liposomes toiletry bag contains following materials in percentage by mass: water 1.2%, the third two Alcohol 0.5%, glycerol 0.7%, trehalose 0.4%, glycine betaine 0.3%, hydrolecithin 0.6%, sodium carboxymethyl starch 0.5%, Acetyl group tetrapeptide -5 0.8%, hydrolytic collagen 1.3%, hyaluronic acid 0.7%, allantoin 0.5%, purslane extract 22.8%, pentapeptide 22.5%, elastin hydrolysis 22.8%, aluminum magnesium silicate 0.2%, Apple cell culture extract 22.8%, 3-o- ethylascorbyl 0.5%, Phenoxyethanol 0.3%, Sensiva SC50 0.6%.
A kind of dual liposomes cosmetics the preparation method comprises the following steps: according to dual liposomes cosmetics materials in percentage by mass Polymerization autoclave is added in all raw materials after proportion, 3-5 hour is reacted into granular raw material, granular raw material is wrapped in In the utricule that diameter is 25-30 nanometers.
Compared with prior art, beneficial effects of the present invention are as follows: wrapping up various active in this dual liposomes cosmetics Ingredient prevents from aoxidizing, and when massage releases the active constituent wrapped up, while moisturizing;Soft massage skin promotes blood Circulation improves the adjustment colour of skin;Securely and reliably, nontoxic to skin, without side-effects, can use everyday.And effectively skin care ingredient is rapid It allows skin to be absorbed, reaches immediately and significant maintenance effect.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction in the embodiment of the present invention, it is clear that institute The embodiment of description is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, Every other embodiment obtained by those of ordinary skill in the art without making creative efforts, belongs to this hair The range of bright protection.
Embodiment 1:
A kind of dual liposomes cosmetics the preparation method comprises the following steps: according to dual liposomes cosmetics materials in percentage by mass Match wherein water 1.2%, propylene glycol 0.5%, glycerol 0.7%, trehalose 0.4%, glycine betaine 0.3%, hydrolecithin 0.6%, sodium carboxymethyl starch 0.5%, acetyl group tetrapeptide -5 0.8%, hydrolytic collagen 1.3%, hyaluronic acid 0.7%, allantoin 0.5%, purslane extract 22.8%, pentapeptide 22.5%, elastin hydrolysis 22.8%, aluminum magnesium silicate 0.2%, Apple Cell culture extract 22.8%, 3-o- ethylascorbyl 0.5%, Phenoxyethanol 0.3%, Sensiva SC50 0.6% Polymerization autoclave is added in all raw materials, reacts 4 hours into granular raw material, it is 28 that granular raw material, which is wrapped in diameter, In the utricule of nanometer.
Embodiment 2:
A kind of dual liposomes cosmetics the preparation method comprises the following steps: according to dual liposomes cosmetics materials in percentage by mass Match wherein water 1.2%, propylene glycol 0.5%, glycerol 0.7%, trehalose 0.4%, glycine betaine 0.3%, hydrolecithin 0.6%, sodium carboxymethyl starch 0.5%, acetyl group tetrapeptide -5 0.8%, hydrolytic collagen 1.3%, hyaluronic acid 0.7%, allantoin 0.5%, purslane extract 20.8%, pentapeptide 20.5%, elastin hydrolysis 24.8%, aluminum magnesium silicate 0.2%, Apple Cell culture extract 24.8%, 3-o- ethylascorbyl 0.5%, Phenoxyethanol 0.3%, Sensiva SC50 0.6% Polymerization autoclave is added in all raw materials, reacts 5 hours into granular raw material, it is 30 that granular raw material, which is wrapped in diameter, In the utricule of nanometer.
Embodiment 3:
A kind of dual liposomes cosmetics the preparation method comprises the following steps: according to dual liposomes cosmetics materials in percentage by mass Match wherein water 1.3%, propylene glycol 0.5%, glycerol 0.5%, trehalose 0.4%, glycine betaine 0.5%, hydrolecithin 0.4%, sodium carboxymethyl starch 0.5%, acetyl group tetrapeptide -5 0.8%, hydrolytic collagen 1.2%, hyaluronic acid 0.8%, allantoin 0.8%, purslane extract 20.5%, pentapeptide 20.8%, elastin hydrolysis 24.5%, aluminum magnesium silicate 0.2%, Apple Cell culture extract 24.8%, 3-o- ethylascorbyl 0.5%, Phenoxyethanol 0.3%, Sensiva SC50 0.6% Polymerization autoclave is added in all raw materials, reacts 3 hours into granular raw material, it is 28 that granular raw material, which is wrapped in diameter, In the utricule of nanometer.
To verify effect of the face cream of the present embodiment in terms of compact skin, moisturizing, 40 volunteers is selected to carry out Validity experiment, using double-dummy design, comparative experiments compares investigation.40 volunteers are the unlimited healthy population of men and women, year Age, 20 one group of people were randomly divided into 2 groups between 25~35 years old.Wherein A group is the dual liposomes using the embodiment of the present invention 1 Cosmetics;B group experiment skin care item conventional on the market.Regular follow-up investigation is carried out to every user, using skin test Instrument, every 10 days primary for stage test, and test position is two sides cheek.As a result it is recorded in following table.
Skin elasticity test
Skin elasticity Average D10-D0 (%) Average D20-D10 (%) Improvement number (%)
A 8.95 7.38 18/20=90%
B 2.25 2.02
Skin moisture test
Skin moisture Average D10-D0 Average D20-D10 Improvement number (%)
A 16.12 13.32 16/20=80%
B 3.68 3.92
From above embodiments and using effect comparison it can be seen that skin elasticity, in terms of, A group test Person's effect after 20 days is obviously improved compared with B group tester, therefore dual liposomes cosmetics of the invention have to skin There is significant maintenance effect.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (3)

1. a kind of dual liposomes cosmetics, it is characterised in that: the toiletry bag contains following materials in percentage by mass: water 1- 3%, propylene glycol 0.3-0.8%, glycerol 0.73-1%, trehalose 0.3-1%, glycine betaine 0.3-0.8%, hydrolecithin 0.3- 0.8%, sodium carboxymethyl starch 0.3-0.8%, acetyl group tetrapeptide -50.6-1.2%, hydrolytic collagen 1.0-1.5%, hyaluronic acid 0.5-1%, allantoin 0.3-1%, purslane extract 20-25%, pentapeptide 20-25%, elastin hydrolysis 20-25%, silicon Sour magnalium 0.1-0.5%, Apple cell culture extract 20-25%, 3-o- ethylascorbyl 0.3-0.8%, benzene Oxyethanol 0.2-0.8%, Sensiva SC50 0.3-0.8%.
2. a kind of dual liposomes cosmetics according to claim 1, it is characterised in that: the dual liposomes makeup Product include following materials in percentage by mass: water 1.2%, propylene glycol 0.5%, glycerol 0.7%, trehalose 0.4%, glycine betaine 0.3%, hydrolecithin 0.6%, sodium carboxymethyl starch 0.5%, acetyl group tetrapeptide -5 0.8%, hydrolytic collagen 1.3%, transparent Matter acid 0.7%, allantoin 0.5%, purslane extract 22.8%, pentapeptide 22.5%, elastin hydrolysis 22.8%, alumina silicate Magnesium 0.2%, Apple cell culture extract 22.8%, 3-o- ethylascorbyl 0.5%, Phenoxyethanol 0.3%, second Base hexyl glycerol 0.6%.
3. a kind of preparation method of dual liposomes cosmetics, it is characterised in that: method particularly includes: it makes up according to dual liposomes All raw material is added polymerization autoclave after the materials in percentage by mass proportion of product, 3-5 hour of reaction at granular raw material, Granular raw material is wrapped in the utricule that diameter is 25-30 nanometers.
CN201910446759.5A 2019-05-27 2019-05-27 A kind of dual liposomes cosmetics Pending CN110169934A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110664635A (en) * 2019-11-05 2020-01-10 湖北创界生物科技有限公司 Moisturizing and hydrating mask composition, mask and preparation method of mask

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105078873A (en) * 2014-05-16 2015-11-25 天津强微特生物科技有限公司 Biological skin protecting composition with tightening and whitening effects
CN107137343A (en) * 2017-07-10 2017-09-08 北京鑫宝洪泽化妆品有限公司 A kind of skin base solution with self-regeneration microecological balance ability and preparation method thereof
CN109481327A (en) * 2018-12-04 2019-03-19 珠海依赛思生物科技有限公司 A kind of multiple-effect maintenance peptide essence composition and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105078873A (en) * 2014-05-16 2015-11-25 天津强微特生物科技有限公司 Biological skin protecting composition with tightening and whitening effects
CN107137343A (en) * 2017-07-10 2017-09-08 北京鑫宝洪泽化妆品有限公司 A kind of skin base solution with self-regeneration microecological balance ability and preparation method thereof
CN109481327A (en) * 2018-12-04 2019-03-19 珠海依赛思生物科技有限公司 A kind of multiple-effect maintenance peptide essence composition and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110664635A (en) * 2019-11-05 2020-01-10 湖北创界生物科技有限公司 Moisturizing and hydrating mask composition, mask and preparation method of mask
CN110664635B (en) * 2019-11-05 2021-05-07 湖北创界生物科技有限公司 Moisturizing and hydrating mask composition, mask and preparation method of mask

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Application publication date: 20190827